Amino acid dipepetide frequency for Folsomia candida (Springtail)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.494AlaAla: 4.494 ± 0.03	0.997AlaCys: 0.997 ± 0.01	2.693AlaAsp: 2.693 ± 0.018	3.403AlaGlu: 3.403 ± 0.019	2.478AlaPhe: 2.478 ± 0.015	3.464AlaGly: 3.464 ± 0.02	1.262AlaHis: 1.262 ± 0.01	3.51AlaIle: 3.51 ± 0.021	3.614AlaLys: 3.614 ± 0.023	5.051AlaLeu: 5.051 ± 0.024	1.411AlaMet: 1.411 ± 0.011	2.664AlaAsn: 2.664 ± 0.017	2.76AlaPro: 2.76 ± 0.023	2.002AlaGln: 2.002 ± 0.013	2.669AlaArg: 2.669 ± 0.014	4.559AlaSer: 4.559 ± 0.026	3.935AlaThr: 3.935 ± 0.023	3.83AlaVal: 3.83 ± 0.021	0.69AlaTrp: 0.69 ± 0.008	1.621AlaTyr: 1.621 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	1.046CysAla: 1.046 ± 0.009	0.479CysCys: 0.479 ± 0.007	1.13CysAsp: 1.13 ± 0.012	1.009CysGlu: 1.009 ± 0.011	0.879CysPhe: 0.879 ± 0.009	1.56CysGly: 1.56 ± 0.013	0.561CysHis: 0.561 ± 0.007	1.093CysIle: 1.093 ± 0.011	1.104CysLys: 1.104 ± 0.011	1.732CysLeu: 1.732 ± 0.012	0.383CysMet: 0.383 ± 0.005	0.877CysAsn: 0.877 ± 0.009	1.2CysPro: 1.2 ± 0.015	0.765CysGln: 0.765 ± 0.009	1.059CysArg: 1.059 ± 0.011	1.617CysSer: 1.617 ± 0.016	1.128CysThr: 1.128 ± 0.011	1.208CysVal: 1.208 ± 0.013	0.293CysTrp: 0.293 ± 0.012	0.643CysTyr: 0.643 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	2.993AspAla: 2.993 ± 0.017	0.928AspCys: 0.928 ± 0.01	4.081AspAsp: 4.081 ± 0.028	4.066AspGlu: 4.066 ± 0.023	2.558AspPhe: 2.558 ± 0.019	3.31AspGly: 3.31 ± 0.021	1.2AspHis: 1.2 ± 0.01	3.03AspIle: 3.03 ± 0.021	3.069AspLys: 3.069 ± 0.018	4.767AspLeu: 4.767 ± 0.028	1.142AspMet: 1.142 ± 0.014	2.464AspAsn: 2.464 ± 0.016	2.735AspPro: 2.735 ± 0.026	1.737AspGln: 1.737 ± 0.012	2.238AspArg: 2.238 ± 0.015	3.779AspSer: 3.779 ± 0.021	2.548AspThr: 2.548 ± 0.018	3.271AspVal: 3.271 ± 0.029	0.69AspTrp: 0.69 ± 0.007	1.674AspTyr: 1.674 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	3.259GluAla: 3.259 ± 0.022	1.007GluCys: 1.007 ± 0.014	3.808GluAsp: 3.808 ± 0.019	5.477GluGlu: 5.477 ± 0.045	2.62GluPhe: 2.62 ± 0.016	3.181GluGly: 3.181 ± 0.023	1.147GluHis: 1.147 ± 0.011	4.177GluIle: 4.177 ± 0.023	4.394GluLys: 4.394 ± 0.034	5.095GluLeu: 5.095 ± 0.024	1.648GluMet: 1.648 ± 0.01	3.39GluAsn: 3.39 ± 0.018	2.051GluPro: 2.051 ± 0.018	2.073GluGln: 2.073 ± 0.016	2.896GluArg: 2.896 ± 0.017	4.222GluSer: 4.222 ± 0.024	3.468GluThr: 3.468 ± 0.027	3.516GluVal: 3.516 ± 0.02	0.754GluTrp: 0.754 ± 0.008	1.745GluTyr: 1.745 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	2.625PheAla: 2.625 ± 0.017	1.05PheCys: 1.05 ± 0.009	2.384PheAsp: 2.384 ± 0.012	2.45PheGlu: 2.45 ± 0.016	2.084PhePhe: 2.084 ± 0.015	3.072PheGly: 3.072 ± 0.024	1.232PheHis: 1.232 ± 0.011	2.716PheIle: 2.716 ± 0.015	2.412PheLys: 2.412 ± 0.015	4.716PheLeu: 4.716 ± 0.026	0.998PheMet: 0.998 ± 0.008	2.05PheAsn: 2.05 ± 0.014	2.456PhePro: 2.456 ± 0.017	1.786PheGln: 1.786 ± 0.012	2.284PheArg: 2.284 ± 0.014	3.77PheSer: 3.77 ± 0.02	2.619PheThr: 2.619 ± 0.018	3.21PheVal: 3.21 ± 0.021	0.654PheTrp: 0.654 ± 0.007	1.622PheTyr: 1.622 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	3.205GlyAla: 3.205 ± 0.019	1.12GlyCys: 1.12 ± 0.012	3.23GlyAsp: 3.23 ± 0.021	3.4GlyGlu: 3.4 ± 0.02	2.719GlyPhe: 2.719 ± 0.016	6.134GlyGly: 6.134 ± 0.077	1.531GlyHis: 1.531 ± 0.012	3.617GlyIle: 3.617 ± 0.018	3.743GlyLys: 3.743 ± 0.018	4.862GlyLeu: 4.862 ± 0.023	1.4GlyMet: 1.4 ± 0.013	3.025GlyAsn: 3.025 ± 0.02	2.449GlyPro: 2.449 ± 0.028	2.281GlyGln: 2.281 ± 0.022	3.3GlyArg: 3.3 ± 0.022	4.999GlySer: 4.999 ± 0.033	3.367GlyThr: 3.367 ± 0.024	3.959GlyVal: 3.959 ± 0.026	0.887GlyTrp: 0.887 ± 0.01	2.109GlyTyr: 2.109 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	1.299HisAla: 1.299 ± 0.015	0.53HisCys: 0.53 ± 0.007	1.129HisAsp: 1.129 ± 0.009	1.248HisGlu: 1.248 ± 0.01	1.283HisPhe: 1.283 ± 0.011	1.505HisGly: 1.505 ± 0.012	1.318HisHis: 1.318 ± 0.019	1.404HisIle: 1.404 ± 0.011	1.248HisLys: 1.248 ± 0.01	2.514HisLeu: 2.514 ± 0.02	0.498HisMet: 0.498 ± 0.007	1.195HisAsn: 1.195 ± 0.011	1.617HisPro: 1.617 ± 0.013	1.105HisGln: 1.105 ± 0.011	1.284HisArg: 1.284 ± 0.011	1.898HisSer: 1.898 ± 0.013	1.241HisThr: 1.241 ± 0.012	1.58HisVal: 1.58 ± 0.016	0.311HisTrp: 0.311 ± 0.005	0.822HisTyr: 0.822 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.329IleAla: 3.329 ± 0.016	1.451IleCys: 1.451 ± 0.016	2.728IleAsp: 2.728 ± 0.016	2.985IleGlu: 2.985 ± 0.019	3.208IlePhe: 3.208 ± 0.02	3.193IleGly: 3.193 ± 0.021	1.475IleHis: 1.475 ± 0.011	3.664IleIle: 3.664 ± 0.02	3.275IleLys: 3.275 ± 0.018	6.387IleLeu: 6.387 ± 0.027	1.325IleMet: 1.325 ± 0.011	2.708IleAsn: 2.708 ± 0.017	3.428IlePro: 3.428 ± 0.02	2.303IleGln: 2.303 ± 0.015	3.091IleArg: 3.091 ± 0.017	5.292IleSer: 5.292 ± 0.025	3.395IleThr: 3.395 ± 0.021	3.87IleVal: 3.87 ± 0.022	0.768IleTrp: 0.768 ± 0.009	1.892IleTyr: 1.892 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	3.111LysAla: 3.111 ± 0.023	1.34LysCys: 1.34 ± 0.013	2.93LysAsp: 2.93 ± 0.017	3.809LysGlu: 3.809 ± 0.024	2.949LysPhe: 2.949 ± 0.016	2.967LysGly: 2.967 ± 0.016	1.322LysHis: 1.322 ± 0.013	4.126LysIle: 4.126 ± 0.024	4.821LysLys: 4.821 ± 0.036	5.939LysLeu: 5.939 ± 0.028	1.642LysMet: 1.642 ± 0.012	3.177LysAsn: 3.177 ± 0.018	2.729LysPro: 2.729 ± 0.025	2.05LysGln: 2.05 ± 0.016	3.376LysArg: 3.376 ± 0.02	4.98LysSer: 4.98 ± 0.023	3.449LysThr: 3.449 ± 0.017	3.679LysVal: 3.679 ± 0.024	0.818LysTrp: 0.818 ± 0.008	2.08LysTyr: 2.08 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	5.546LeuAla: 5.546 ± 0.024	1.737LeuCys: 1.737 ± 0.013	4.736LeuAsp: 4.736 ± 0.024	5.624LeuGlu: 5.624 ± 0.029	3.927LeuPhe: 3.927 ± 0.021	5.221LeuGly: 5.221 ± 0.028	2.383LeuHis: 2.383 ± 0.015	5.344LeuIle: 5.344 ± 0.024	5.883LeuLys: 5.883 ± 0.028	8.933LeuLeu: 8.933 ± 0.039	1.993LeuMet: 1.993 ± 0.015	4.33LeuAsn: 4.33 ± 0.02	4.953LeuPro: 4.953 ± 0.025	3.921LeuGln: 3.921 ± 0.018	4.979LeuArg: 4.979 ± 0.019	7.242LeuSer: 7.242 ± 0.028	5.464LeuThr: 5.464 ± 0.024	5.818LeuVal: 5.818 ± 0.019	1.069LeuTrp: 1.069 ± 0.009	2.599LeuTyr: 2.599 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	1.539MetAla: 1.539 ± 0.012	0.386MetCys: 0.386 ± 0.006	1.384MetAsp: 1.384 ± 0.012	1.651MetGlu: 1.651 ± 0.012	0.938MetPhe: 0.938 ± 0.008	1.42MetGly: 1.42 ± 0.012	0.489MetHis: 0.489 ± 0.007	1.21MetIle: 1.21 ± 0.01	1.558MetLys: 1.558 ± 0.015	1.85MetLeu: 1.85 ± 0.012	0.686MetMet: 0.686 ± 0.009	1.018MetAsn: 1.018 ± 0.01	0.976MetPro: 0.976 ± 0.01	0.858MetGln: 0.858 ± 0.009	1.125MetArg: 1.125 ± 0.01	1.889MetSer: 1.889 ± 0.012	1.434MetThr: 1.434 ± 0.01	1.342MetVal: 1.342 ± 0.01	0.292MetTrp: 0.292 ± 0.005	0.643MetTyr: 0.643 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.603AsnAla: 2.603 ± 0.018	1.089AsnCys: 1.089 ± 0.011	2.338AsnAsp: 2.338 ± 0.016	2.625AsnGlu: 2.625 ± 0.015	2.672AsnPhe: 2.672 ± 0.017	3.127AsnGly: 3.127 ± 0.021	1.254AsnHis: 1.254 ± 0.011	2.909AsnIle: 2.909 ± 0.018	2.693AsnLys: 2.693 ± 0.017	4.981AsnLeu: 4.981 ± 0.03	1.103AsnMet: 1.103 ± 0.01	3.193AsnAsn: 3.193 ± 0.029	2.735AsnPro: 2.735 ± 0.016	1.857AsnGln: 1.857 ± 0.015	2.22AsnArg: 2.22 ± 0.016	4.294AsnSer: 4.294 ± 0.022	2.301AsnThr: 2.301 ± 0.014	3.073AsnVal: 3.073 ± 0.018	0.651AsnTrp: 0.651 ± 0.007	1.831AsnTyr: 1.831 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	2.995ProAla: 2.995 ± 0.023	0.913ProCys: 0.913 ± 0.014	2.547ProAsp: 2.547 ± 0.017	3.088ProGlu: 3.088 ± 0.024	2.241ProPhe: 2.241 ± 0.015	2.848ProGly: 2.848 ± 0.029	1.345ProHis: 1.345 ± 0.015	2.996ProIle: 2.996 ± 0.019	2.958ProLys: 2.958 ± 0.022	4.361ProLeu: 4.361 ± 0.021	0.958ProMet: 0.958 ± 0.009	2.581ProAsn: 2.581 ± 0.021	4.88ProPro: 4.88 ± 0.054	2.112ProGln: 2.112 ± 0.022	2.427ProArg: 2.427 ± 0.015	4.86ProSer: 4.86 ± 0.03	3.966ProThr: 3.966 ± 0.045	3.278ProVal: 3.278 ± 0.024	0.596ProTrp: 0.596 ± 0.008	1.434ProTyr: 1.434 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	2.036GlnAla: 2.036 ± 0.016	0.716GlnCys: 0.716 ± 0.011	1.847GlnAsp: 1.847 ± 0.013	2.353GlnGlu: 2.353 ± 0.018	1.767GlnPhe: 1.767 ± 0.011	1.986GlnGly: 1.986 ± 0.02	1.056GlnHis: 1.056 ± 0.015	2.559GlnIle: 2.559 ± 0.017	2.253GlnLys: 2.253 ± 0.016	3.546GlnLeu: 3.546 ± 0.019	0.895GlnMet: 0.895 ± 0.012	2.141GlnAsn: 2.141 ± 0.013	1.964GlnPro: 1.964 ± 0.022	2.597GlnGln: 2.597 ± 0.042	2.003GlnArg: 2.003 ± 0.015	2.708GlnSer: 2.708 ± 0.018	2.069GlnThr: 2.069 ± 0.014	2.331GlnVal: 2.331 ± 0.014	0.418GlnTrp: 0.418 ± 0.006	1.125GlnTyr: 1.125 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	2.451ArgAla: 2.451 ± 0.016	0.966ArgCys: 0.966 ± 0.012	2.577ArgAsp: 2.577 ± 0.016	2.85ArgGlu: 2.85 ± 0.019	2.265ArgPhe: 2.265 ± 0.015	2.989ArgGly: 2.989 ± 0.026	1.486ArgHis: 1.486 ± 0.012	3.027ArgIle: 3.027 ± 0.018	3.766ArgLys: 3.766 ± 0.019	4.458ArgLeu: 4.458 ± 0.021	1.188ArgMet: 1.188 ± 0.01	2.831ArgAsn: 2.831 ± 0.015	2.587ArgPro: 2.587 ± 0.021	2.008ArgGln: 2.008 ± 0.013	3.698ArgArg: 3.698 ± 0.025	3.747ArgSer: 3.747 ± 0.019	2.631ArgThr: 2.631 ± 0.015	2.976ArgVal: 2.976 ± 0.016	0.665ArgTrp: 0.665 ± 0.007	1.544ArgTyr: 1.544 ± 0.011	0.0ArgXaa: 0.0 ± 0.0
Ser	4.567SerAla: 4.567 ± 0.023	1.616SerCys: 1.616 ± 0.015	4.197SerAsp: 4.197 ± 0.026	4.309SerGlu: 4.309 ± 0.021	3.51SerPhe: 3.51 ± 0.017	5.257SerGly: 5.257 ± 0.033	2.062SerHis: 2.062 ± 0.019	4.523SerIle: 4.523 ± 0.021	4.637SerLys: 4.637 ± 0.02	7.211SerLeu: 7.211 ± 0.032	1.615SerMet: 1.615 ± 0.011	4.04SerAsn: 4.04 ± 0.024	4.819SerPro: 4.819 ± 0.034	3.008SerGln: 3.008 ± 0.017	4.028SerArg: 4.028 ± 0.021	10.132SerSer: 10.132 ± 0.069	5.634SerThr: 5.634 ± 0.034	4.764SerVal: 4.764 ± 0.024	0.992SerTrp: 0.992 ± 0.009	2.375SerTyr: 2.375 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	3.468ThrAla: 3.468 ± 0.018	1.298ThrCys: 1.298 ± 0.013	2.655ThrAsp: 2.655 ± 0.024	3.253ThrGlu: 3.253 ± 0.034	2.968ThrPhe: 2.968 ± 0.02	3.44ThrGly: 3.44 ± 0.023	1.337ThrHis: 1.337 ± 0.013	3.624ThrIle: 3.624 ± 0.021	3.34ThrLys: 3.34 ± 0.018	5.557ThrLeu: 5.557 ± 0.027	1.322ThrMet: 1.322 ± 0.01	2.886ThrAsn: 2.886 ± 0.016	3.85ThrPro: 3.85 ± 0.043	1.926ThrGln: 1.926 ± 0.014	2.812ThrArg: 2.812 ± 0.014	5.456ThrSer: 5.456 ± 0.032	5.958ThrThr: 5.958 ± 0.094	3.638ThrVal: 3.638 ± 0.019	0.803ThrTrp: 0.803 ± 0.009	1.727ThrTyr: 1.727 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.112ValAla: 4.112 ± 0.024	1.239ValCys: 1.239 ± 0.012	3.406ValAsp: 3.406 ± 0.024	3.872ValGlu: 3.872 ± 0.021	2.745ValPhe: 2.745 ± 0.023	3.836ValGly: 3.836 ± 0.019	1.469ValHis: 1.469 ± 0.01	3.688ValIle: 3.688 ± 0.02	3.89ValLys: 3.89 ± 0.021	5.661ValLeu: 5.661 ± 0.024	1.44ValMet: 1.44 ± 0.012	2.765ValAsn: 2.765 ± 0.025	3.155ValPro: 3.155 ± 0.022	2.404ValGln: 2.404 ± 0.015	2.877ValArg: 2.877 ± 0.017	4.581ValSer: 4.581 ± 0.023	4.18ValThr: 4.18 ± 0.024	4.637ValVal: 4.637 ± 0.029	0.83ValTrp: 0.83 ± 0.01	1.786ValTyr: 1.786 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.702TrpAla: 0.702 ± 0.007	0.208TrpCys: 0.208 ± 0.004	0.755TrpAsp: 0.755 ± 0.009	0.797TrpGlu: 0.797 ± 0.008	0.523TrpPhe: 0.523 ± 0.007	0.876TrpGly: 0.876 ± 0.014	0.239TrpHis: 0.239 ± 0.005	0.919TrpIle: 0.919 ± 0.009	0.94TrpLys: 0.94 ± 0.008	1.111TrpLeu: 1.111 ± 0.01	0.382TrpMet: 0.382 ± 0.005	0.696TrpAsn: 0.696 ± 0.008	0.445TrpPro: 0.445 ± 0.005	0.363TrpGln: 0.363 ± 0.005	0.735TrpArg: 0.735 ± 0.007	0.92TrpSer: 0.92 ± 0.01	0.864TrpThr: 0.864 ± 0.008	0.779TrpVal: 0.779 ± 0.008	0.231TrpTrp: 0.231 ± 0.005	0.381TrpTyr: 0.381 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.727TyrAla: 1.727 ± 0.013	0.695TyrCys: 0.695 ± 0.008	1.727TyrAsp: 1.727 ± 0.025	1.657TyrGlu: 1.657 ± 0.012	1.858TyrPhe: 1.858 ± 0.013	1.947TyrGly: 1.947 ± 0.018	0.862TyrHis: 0.862 ± 0.008	1.632TyrIle: 1.632 ± 0.012	1.701TyrLys: 1.701 ± 0.013	2.968TyrLeu: 2.968 ± 0.018	0.659TyrMet: 0.659 ± 0.006	1.516TyrAsn: 1.516 ± 0.012	1.596TyrPro: 1.596 ± 0.013	1.213TyrGln: 1.213 ± 0.013	1.609TyrArg: 1.609 ± 0.015	2.353TyrSer: 2.353 ± 0.015	1.664TyrThr: 1.664 ± 0.012	1.817TyrVal: 1.817 ± 0.013	0.452TyrTrp: 0.452 ± 0.008	1.205TyrTyr: 1.205 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 28565 proteins (14149570 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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