Amino acid dipepetide frequency for Gemycircularvirus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.199AlaAla: 1.199 ± 0.838
1.199AlaCys: 1.199 ± 0.838
3.597AlaAsp: 3.597 ± 1.346
4.796AlaGlu: 4.796 ± 3.353
3.597AlaPhe: 3.597 ± 1.346
3.597AlaGly: 3.597 ± 1.421
0.0AlaHis: 0.0 ± 0.0
3.597AlaIle: 3.597 ± 0.518
3.597AlaLys: 3.597 ± 1.642
2.398AlaLeu: 2.398 ± 1.677
4.796AlaMet: 4.796 ± 0.824
0.0AlaAsn: 0.0 ± 0.0
2.398AlaPro: 2.398 ± 1.757
1.199AlaGln: 1.199 ± 0.838
10.791AlaArg: 10.791 ± 3.417
3.597AlaSer: 3.597 ± 2.324
1.199AlaThr: 1.199 ± 1.284
1.199AlaVal: 1.199 ± 0.838
0.0AlaTrp: 0.0 ± 0.0
3.597AlaTyr: 3.597 ± 1.346
0.0AlaXaa: 0.0 ± 0.0
Cys
1.199CysAla: 1.199 ± 0.838
0.0CysCys: 0.0 ± 0.0
2.398CysAsp: 2.398 ± 1.677
0.0CysGlu: 0.0 ± 0.0
1.199CysPhe: 1.199 ± 0.879
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.398CysIle: 2.398 ± 1.677
1.199CysLys: 1.199 ± 0.838
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.199CysAsn: 1.199 ± 0.879
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.199CysVal: 1.199 ± 0.838
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
4.796AspAsp: 4.796 ± 2.107
4.796AspGlu: 4.796 ± 1.801
1.199AspPhe: 1.199 ± 0.838
5.995AspGly: 5.995 ± 3.017
3.597AspHis: 3.597 ± 1.601
5.995AspIle: 5.995 ± 2.108
2.398AspLys: 2.398 ± 0.767
7.194AspLeu: 7.194 ± 2.476
1.199AspMet: 1.199 ± 0.838
1.199AspAsn: 1.199 ± 0.838
2.398AspPro: 2.398 ± 1.677
2.398AspGln: 2.398 ± 1.677
2.398AspArg: 2.398 ± 1.183
4.796AspSer: 4.796 ± 0.824
4.796AspThr: 4.796 ± 2.353
7.194AspVal: 7.194 ± 5.03
2.398AspTrp: 2.398 ± 0.767
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.199GluAla: 1.199 ± 1.284
1.199GluCys: 1.199 ± 0.838
3.597GluAsp: 3.597 ± 1.601
0.0GluGlu: 0.0 ± 0.0
1.199GluPhe: 1.199 ± 0.838
2.398GluGly: 2.398 ± 0.767
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
2.398GluLys: 2.398 ± 1.183
5.995GluLeu: 5.995 ± 3.458
1.199GluMet: 1.199 ± 0.678
3.597GluAsn: 3.597 ± 2.307
1.199GluPro: 1.199 ± 1.284
1.199GluGln: 1.199 ± 0.879
4.796GluArg: 4.796 ± 1.801
7.194GluSer: 7.194 ± 2.692
2.398GluThr: 2.398 ± 1.183
3.597GluVal: 3.597 ± 2.324
1.199GluTrp: 1.199 ± 0.838
1.199GluTyr: 1.199 ± 0.838
0.0GluXaa: 0.0 ± 0.0
Phe
2.398PheAla: 2.398 ± 1.184
1.199PheCys: 1.199 ± 0.838
3.597PheAsp: 3.597 ± 1.601
0.0PheGlu: 0.0 ± 0.0
2.398PhePhe: 2.398 ± 1.184
4.796PheGly: 4.796 ± 3.353
1.199PheHis: 1.199 ± 0.838
2.398PheIle: 2.398 ± 0.767
2.398PheLys: 2.398 ± 0.767
7.194PheLeu: 7.194 ± 4.369
0.0PheMet: 0.0 ± 0.0
2.398PheAsn: 2.398 ± 0.767
3.597PhePro: 3.597 ± 1.601
1.199PheGln: 1.199 ± 1.284
3.597PheArg: 3.597 ± 1.346
3.597PheSer: 3.597 ± 2.636
2.398PheThr: 2.398 ± 1.757
1.199PheVal: 1.199 ± 0.838
0.0PheTrp: 0.0 ± 0.0
2.398PheTyr: 2.398 ± 0.767
0.0PheXaa: 0.0 ± 0.0
Gly
8.393GlyAla: 8.393 ± 2.75
0.0GlyCys: 0.0 ± 0.0
2.398GlyAsp: 2.398 ± 0.767
2.398GlyGlu: 2.398 ± 0.767
2.398GlyPhe: 2.398 ± 1.184
7.194GlyGly: 7.194 ± 3.73
0.0GlyHis: 0.0 ± 0.0
1.199GlyIle: 1.199 ± 0.838
3.597GlyLys: 3.597 ± 1.346
8.393GlyLeu: 8.393 ± 0.959
1.199GlyMet: 1.199 ± 0.879
4.796GlyAsn: 4.796 ± 2.235
5.995GlyPro: 5.995 ± 1.623
1.199GlyGln: 1.199 ± 0.838
1.199GlyArg: 1.199 ± 0.838
8.393GlySer: 8.393 ± 2.332
8.393GlyThr: 8.393 ± 3.343
3.597GlyVal: 3.597 ± 1.421
1.199GlyTrp: 1.199 ± 0.879
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.199HisAla: 1.199 ± 0.838
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.199HisGlu: 1.199 ± 0.879
2.398HisPhe: 2.398 ± 1.677
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.199HisIle: 1.199 ± 0.879
0.0HisLys: 0.0 ± 0.0
2.398HisLeu: 2.398 ± 1.677
1.199HisMet: 1.199 ± 1.284
0.0HisAsn: 0.0 ± 0.0
1.199HisPro: 1.199 ± 0.838
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.199HisSer: 1.199 ± 1.284
0.0HisThr: 0.0 ± 0.0
2.398HisVal: 2.398 ± 0.767
1.199HisTrp: 1.199 ± 1.284
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.199IleAla: 1.199 ± 0.838
0.0IleCys: 0.0 ± 0.0
2.398IleAsp: 2.398 ± 0.767
3.597IleGlu: 3.597 ± 1.421
3.597IlePhe: 3.597 ± 1.346
1.199IleGly: 1.199 ± 0.879
1.199IleHis: 1.199 ± 0.879
0.0IleIle: 0.0 ± 0.0
1.199IleLys: 1.199 ± 0.879
8.393IleLeu: 8.393 ± 2.793
1.199IleMet: 1.199 ± 1.284
0.0IleAsn: 0.0 ± 0.0
1.199IlePro: 1.199 ± 0.838
0.0IleGln: 0.0 ± 0.0
1.199IleArg: 1.199 ± 0.879
4.796IleSer: 4.796 ± 1.801
2.398IleThr: 2.398 ± 1.677
4.796IleVal: 4.796 ± 1.535
1.199IleTrp: 1.199 ± 0.838
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.199LysAla: 1.199 ± 0.838
0.0LysCys: 0.0 ± 0.0
3.597LysAsp: 3.597 ± 2.515
0.0LysGlu: 0.0 ± 0.0
2.398LysPhe: 2.398 ± 1.677
2.398LysGly: 2.398 ± 0.767
0.0LysHis: 0.0 ± 0.0
1.199LysIle: 1.199 ± 1.284
5.995LysLys: 5.995 ± 3.084
2.398LysLeu: 2.398 ± 1.183
2.398LysMet: 2.398 ± 1.536
4.796LysAsn: 4.796 ± 2.235
1.199LysPro: 1.199 ± 0.838
0.0LysGln: 0.0 ± 0.0
5.995LysArg: 5.995 ± 4.394
4.796LysSer: 4.796 ± 2.235
3.597LysThr: 3.597 ± 2.324
1.199LysVal: 1.199 ± 1.284
2.398LysTrp: 2.398 ± 1.677
3.597LysTyr: 3.597 ± 1.421
0.0LysXaa: 0.0 ± 0.0
Leu
2.398LeuAla: 2.398 ± 1.677
1.199LeuCys: 1.199 ± 0.838
7.194LeuAsp: 7.194 ± 3.553
3.597LeuGlu: 3.597 ± 3.851
3.597LeuPhe: 3.597 ± 2.307
2.398LeuGly: 2.398 ± 1.677
2.398LeuHis: 2.398 ± 0.767
2.398LeuIle: 2.398 ± 1.184
4.796LeuLys: 4.796 ± 2.366
8.393LeuLeu: 8.393 ± 7.372
3.597LeuMet: 3.597 ± 3.851
4.796LeuAsn: 4.796 ± 0.737
3.597LeuPro: 3.597 ± 1.421
2.398LeuGln: 2.398 ± 1.183
9.592LeuArg: 9.592 ± 2.099
4.796LeuSer: 4.796 ± 5.135
8.393LeuThr: 8.393 ± 1.936
7.194LeuVal: 7.194 ± 2.304
1.199LeuTrp: 1.199 ± 1.284
4.796LeuTyr: 4.796 ± 1.535
0.0LeuXaa: 0.0 ± 0.0
Met
2.398MetAla: 2.398 ± 1.183
0.0MetCys: 0.0 ± 0.0
1.199MetAsp: 1.199 ± 0.879
2.398MetGlu: 2.398 ± 2.568
2.398MetPhe: 2.398 ± 1.183
2.398MetGly: 2.398 ± 0.767
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.199MetLys: 1.199 ± 0.838
5.995MetLeu: 5.995 ± 3.085
1.199MetMet: 1.199 ± 0.879
1.199MetAsn: 1.199 ± 1.284
1.199MetPro: 1.199 ± 1.284
3.597MetGln: 3.597 ± 1.421
1.199MetArg: 1.199 ± 1.284
1.199MetSer: 1.199 ± 0.879
1.199MetThr: 1.199 ± 0.838
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.597AsnAla: 3.597 ± 1.346
1.199AsnCys: 1.199 ± 0.838
3.597AsnAsp: 3.597 ± 1.421
1.199AsnGlu: 1.199 ± 1.284
2.398AsnPhe: 2.398 ± 2.568
3.597AsnGly: 3.597 ± 2.307
1.199AsnHis: 1.199 ± 1.284
2.398AsnIle: 2.398 ± 0.767
1.199AsnLys: 1.199 ± 0.879
2.398AsnLeu: 2.398 ± 1.757
0.0AsnMet: 0.0 ± 0.0
1.199AsnAsn: 1.199 ± 0.879
2.398AsnPro: 2.398 ± 0.767
3.597AsnGln: 3.597 ± 1.421
3.597AsnArg: 3.597 ± 1.421
3.597AsnSer: 3.597 ± 2.636
4.796AsnThr: 4.796 ± 2.235
1.199AsnVal: 1.199 ± 0.879
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.398ProAla: 2.398 ± 1.183
1.199ProCys: 1.199 ± 0.879
3.597ProAsp: 3.597 ± 0.518
3.597ProGlu: 3.597 ± 1.601
0.0ProPhe: 0.0 ± 0.0
5.995ProGly: 5.995 ± 0.257
1.199ProHis: 1.199 ± 0.838
2.398ProIle: 2.398 ± 0.767
1.199ProLys: 1.199 ± 0.838
4.796ProLeu: 4.796 ± 5.135
1.199ProMet: 1.199 ± 1.076
2.398ProAsn: 2.398 ± 0.767
3.597ProPro: 3.597 ± 2.324
2.398ProGln: 2.398 ± 1.677
2.398ProArg: 2.398 ± 1.677
4.796ProSer: 4.796 ± 5.135
7.194ProThr: 7.194 ± 1.065
0.0ProVal: 0.0 ± 0.0
2.398ProTrp: 2.398 ± 1.757
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.199GlnCys: 1.199 ± 0.838
2.398GlnAsp: 2.398 ± 0.767
1.199GlnGlu: 1.199 ± 1.284
0.0GlnPhe: 0.0 ± 0.0
1.199GlnGly: 1.199 ± 0.838
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.398GlnLeu: 2.398 ± 1.677
1.199GlnMet: 1.199 ± 1.284
2.398GlnAsn: 2.398 ± 1.757
1.199GlnPro: 1.199 ± 0.838
0.0GlnGln: 0.0 ± 0.0
4.796GlnArg: 4.796 ± 0.737
1.199GlnSer: 1.199 ± 1.284
2.398GlnThr: 2.398 ± 1.757
2.398GlnVal: 2.398 ± 0.767
0.0GlnTrp: 0.0 ± 0.0
4.796GlnTyr: 4.796 ± 2.235
0.0GlnXaa: 0.0 ± 0.0
Arg
8.393ArgAla: 8.393 ± 1.749
0.0ArgCys: 0.0 ± 0.0
7.194ArgAsp: 7.194 ± 0.927
3.597ArgGlu: 3.597 ± 1.346
1.199ArgPhe: 1.199 ± 0.838
5.995ArgGly: 5.995 ± 3.15
0.0ArgHis: 0.0 ± 0.0
4.796ArgIle: 4.796 ± 2.366
8.393ArgLys: 8.393 ± 1.936
3.597ArgLeu: 3.597 ± 1.421
1.199ArgMet: 1.199 ± 0.879
0.0ArgAsn: 0.0 ± 0.0
1.199ArgPro: 1.199 ± 0.879
0.0ArgGln: 0.0 ± 0.0
5.995ArgArg: 5.995 ± 1.622
5.995ArgSer: 5.995 ± 1.491
5.995ArgThr: 5.995 ± 3.085
5.995ArgVal: 5.995 ± 1.623
2.398ArgTrp: 2.398 ± 1.677
3.597ArgTyr: 3.597 ± 1.346
0.0ArgXaa: 0.0 ± 0.0
Ser
4.796SerAla: 4.796 ± 1.801
0.0SerCys: 0.0 ± 0.0
4.796SerAsp: 4.796 ± 0.824
0.0SerGlu: 0.0 ± 0.0
2.398SerPhe: 2.398 ± 0.767
9.592SerGly: 9.592 ± 1.647
1.199SerHis: 1.199 ± 0.838
2.398SerIle: 2.398 ± 1.757
3.597SerLys: 3.597 ± 1.421
3.597SerLeu: 3.597 ± 1.346
2.398SerMet: 2.398 ± 2.568
1.199SerAsn: 1.199 ± 0.879
9.592SerPro: 9.592 ± 5.332
4.796SerGln: 4.796 ± 0.824
3.597SerArg: 3.597 ± 1.421
9.592SerSer: 9.592 ± 4.339
13.189SerThr: 13.189 ± 2.614
5.995SerVal: 5.995 ± 1.623
3.597SerTrp: 3.597 ± 3.851
3.597SerTyr: 3.597 ± 1.421
0.0SerXaa: 0.0 ± 0.0
Thr
5.995ThrAla: 5.995 ± 4.394
1.199ThrCys: 1.199 ± 0.879
3.597ThrAsp: 3.597 ± 1.346
4.796ThrGlu: 4.796 ± 2.369
5.995ThrPhe: 5.995 ± 1.603
4.796ThrGly: 4.796 ± 0.824
2.398ThrHis: 2.398 ± 1.184
4.796ThrIle: 4.796 ± 0.737
2.398ThrLys: 2.398 ± 0.767
5.995ThrLeu: 5.995 ± 1.603
1.199ThrMet: 1.199 ± 0.879
4.796ThrAsn: 4.796 ± 2.353
4.796ThrPro: 4.796 ± 2.353
1.199ThrGln: 1.199 ± 0.879
5.995ThrArg: 5.995 ± 3.085
9.592ThrSer: 9.592 ± 7.03
3.597ThrThr: 3.597 ± 0.518
0.0ThrVal: 0.0 ± 0.0
1.199ThrTrp: 1.199 ± 0.838
2.398ThrTyr: 2.398 ± 0.767
0.0ThrXaa: 0.0 ± 0.0
Val
3.597ValAla: 3.597 ± 2.515
1.199ValCys: 1.199 ± 0.838
4.796ValAsp: 4.796 ± 2.235
2.398ValGlu: 2.398 ± 0.767
3.597ValPhe: 3.597 ± 1.421
2.398ValGly: 2.398 ± 0.767
0.0ValHis: 0.0 ± 0.0
2.398ValIle: 2.398 ± 0.767
1.199ValLys: 1.199 ± 0.838
3.597ValLeu: 3.597 ± 2.324
1.199ValMet: 1.199 ± 0.838
5.995ValAsn: 5.995 ± 0.257
2.398ValPro: 2.398 ± 2.568
3.597ValGln: 3.597 ± 0.518
2.398ValArg: 2.398 ± 1.677
5.995ValSer: 5.995 ± 1.623
3.597ValThr: 3.597 ± 1.346
3.597ValVal: 3.597 ± 1.421
0.0ValTrp: 0.0 ± 0.0
2.398ValTyr: 2.398 ± 1.677
0.0ValXaa: 0.0 ± 0.0
Trp
1.199TrpAla: 1.199 ± 0.838
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.597TrpGlu: 3.597 ± 2.307
2.398TrpPhe: 2.398 ± 0.767
2.398TrpGly: 2.398 ± 0.767
1.199TrpHis: 1.199 ± 0.879
0.0TrpIle: 0.0 ± 0.0
1.199TrpLys: 1.199 ± 0.838
3.597TrpLeu: 3.597 ± 1.601
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.398TrpPro: 2.398 ± 1.184
0.0TrpGln: 0.0 ± 0.0
1.199TrpArg: 1.199 ± 0.879
2.398TrpSer: 2.398 ± 0.767
1.199TrpThr: 1.199 ± 1.284
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.199TrpTyr: 1.199 ± 0.879
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.597TyrAla: 3.597 ± 2.515
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.398TyrGlu: 2.398 ± 1.677
3.597TyrPhe: 3.597 ± 1.346
3.597TyrGly: 3.597 ± 1.421
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.199TyrLys: 1.199 ± 0.838
0.0TyrLeu: 0.0 ± 0.0
1.199TyrMet: 1.199 ± 0.838
1.199TyrAsn: 1.199 ± 0.879
2.398TyrPro: 2.398 ± 0.767
0.0TyrGln: 0.0 ± 0.0
4.796TyrArg: 4.796 ± 2.235
2.398TyrSer: 2.398 ± 0.767
0.0TyrThr: 0.0 ± 0.0
3.597TyrVal: 3.597 ± 1.421
3.597TyrTrp: 3.597 ± 2.636
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (835 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski