Amino acid dipepetide frequency for Leptonychotes weddellii papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.369AlaAla: 6.369 ± 1.831
0.425AlaCys: 0.425 ± 0.37
4.246AlaAsp: 4.246 ± 1.313
6.369AlaGlu: 6.369 ± 0.812
2.972AlaPhe: 2.972 ± 0.882
2.972AlaGly: 2.972 ± 1.342
1.274AlaHis: 1.274 ± 0.423
2.123AlaIle: 2.123 ± 0.848
2.548AlaLys: 2.548 ± 1.487
5.52AlaLeu: 5.52 ± 1.632
0.425AlaMet: 0.425 ± 0.412
2.123AlaAsn: 2.123 ± 1.422
2.972AlaPro: 2.972 ± 1.172
2.972AlaGln: 2.972 ± 0.575
2.972AlaArg: 2.972 ± 1.575
3.822AlaSer: 3.822 ± 1.086
2.123AlaThr: 2.123 ± 1.047
3.397AlaVal: 3.397 ± 1.827
0.849AlaTrp: 0.849 ± 0.596
2.548AlaTyr: 2.548 ± 1.24
0.0AlaXaa: 0.0 ± 0.0
Cys
1.699CysAla: 1.699 ± 0.965
0.425CysCys: 0.425 ± 0.529
0.425CysAsp: 0.425 ± 0.529
0.0CysGlu: 0.0 ± 0.0
1.699CysPhe: 1.699 ± 0.843
2.548CysGly: 2.548 ± 1.285
0.425CysHis: 0.425 ± 0.529
0.849CysIle: 0.849 ± 0.573
2.123CysLys: 2.123 ± 0.96
1.274CysLeu: 1.274 ± 0.859
0.849CysMet: 0.849 ± 0.74
0.0CysAsn: 0.0 ± 0.0
1.699CysPro: 1.699 ± 0.573
0.849CysGln: 0.849 ± 0.77
0.849CysArg: 0.849 ± 0.573
2.123CysSer: 2.123 ± 0.718
0.849CysThr: 0.849 ± 0.424
0.849CysVal: 0.849 ± 0.624
0.425CysTrp: 0.425 ± 0.37
0.425CysTyr: 0.425 ± 0.519
0.0CysXaa: 0.0 ± 0.0
Asp
5.945AspAla: 5.945 ± 1.925
1.699AspCys: 1.699 ± 0.864
2.123AspAsp: 2.123 ± 0.888
6.369AspGlu: 6.369 ± 1.085
1.274AspPhe: 1.274 ± 0.445
3.822AspGly: 3.822 ± 1.267
0.849AspHis: 0.849 ± 0.495
4.246AspIle: 4.246 ± 1.25
4.246AspLys: 4.246 ± 1.077
5.096AspLeu: 5.096 ± 2.104
0.849AspMet: 0.849 ± 0.424
3.397AspAsn: 3.397 ± 0.961
3.397AspPro: 3.397 ± 1.73
1.274AspGln: 1.274 ± 0.708
0.849AspArg: 0.849 ± 0.495
5.096AspSer: 5.096 ± 1.261
2.123AspThr: 2.123 ± 0.559
3.822AspVal: 3.822 ± 0.65
0.849AspTrp: 0.849 ± 0.74
1.699AspTyr: 1.699 ± 0.675
0.0AspXaa: 0.0 ± 0.0
Glu
2.123GluAla: 2.123 ± 0.808
0.425GluCys: 0.425 ± 0.37
3.397GluAsp: 3.397 ± 1.02
7.219GluGlu: 7.219 ± 2.041
1.699GluPhe: 1.699 ± 0.848
3.397GluGly: 3.397 ± 1.066
0.849GluHis: 0.849 ± 0.756
2.548GluIle: 2.548 ± 0.802
3.822GluLys: 3.822 ± 1.512
8.068GluLeu: 8.068 ± 1.879
0.425GluMet: 0.425 ± 0.416
5.52GluAsn: 5.52 ± 1.178
3.397GluPro: 3.397 ± 0.774
4.246GluGln: 4.246 ± 1.148
3.822GluArg: 3.822 ± 1.182
2.548GluSer: 2.548 ± 1.163
3.397GluThr: 3.397 ± 1.325
4.246GluVal: 4.246 ± 1.173
1.274GluTrp: 1.274 ± 0.743
1.274GluTyr: 1.274 ± 1.134
0.0GluXaa: 0.0 ± 0.0
Phe
2.123PheAla: 2.123 ± 0.401
2.123PheCys: 2.123 ± 1.28
4.671PheAsp: 4.671 ± 1.267
2.548PheGlu: 2.548 ± 1.489
4.246PhePhe: 4.246 ± 1.403
2.123PheGly: 2.123 ± 0.912
0.849PheHis: 0.849 ± 0.424
1.274PheIle: 1.274 ± 0.334
3.397PheLys: 3.397 ± 1.669
5.945PheLeu: 5.945 ± 1.451
1.699PheMet: 1.699 ± 0.559
2.548PheAsn: 2.548 ± 0.989
2.123PhePro: 2.123 ± 0.944
2.123PheGln: 2.123 ± 0.689
1.699PheArg: 1.699 ± 0.669
2.123PheSer: 2.123 ± 1.009
2.972PheThr: 2.972 ± 1.184
2.123PheVal: 2.123 ± 0.756
1.699PheTrp: 1.699 ± 0.654
1.699PheTyr: 1.699 ± 1.119
0.0PheXaa: 0.0 ± 0.0
Gly
1.699GlyAla: 1.699 ± 0.59
0.849GlyCys: 0.849 ± 0.596
5.52GlyAsp: 5.52 ± 1.615
4.671GlyGlu: 4.671 ± 1.592
1.699GlyPhe: 1.699 ± 0.559
6.369GlyGly: 6.369 ± 3.45
0.849GlyHis: 0.849 ± 0.756
2.123GlyIle: 2.123 ± 0.756
2.972GlyLys: 2.972 ± 1.517
6.369GlyLeu: 6.369 ± 1.29
1.699GlyMet: 1.699 ± 0.605
3.397GlyAsn: 3.397 ± 1.064
2.972GlyPro: 2.972 ± 1.184
2.972GlyGln: 2.972 ± 0.372
4.246GlyArg: 4.246 ± 0.873
3.822GlySer: 3.822 ± 1.543
3.822GlyThr: 3.822 ± 1.158
5.945GlyVal: 5.945 ± 1.324
0.0GlyTrp: 0.0 ± 0.0
0.849GlyTyr: 0.849 ± 0.781
0.0GlyXaa: 0.0 ± 0.0
His
0.849HisAla: 0.849 ± 0.495
0.849HisCys: 0.849 ± 0.636
1.274HisAsp: 1.274 ± 0.334
0.849HisGlu: 0.849 ± 0.424
1.274HisPhe: 1.274 ± 0.672
0.849HisGly: 0.849 ± 0.611
0.425HisHis: 0.425 ± 0.37
0.849HisIle: 0.849 ± 0.473
0.849HisLys: 0.849 ± 0.424
1.274HisLeu: 1.274 ± 0.713
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.849HisPro: 0.849 ± 0.429
1.699HisGln: 1.699 ± 0.947
0.849HisArg: 0.849 ± 0.573
1.699HisSer: 1.699 ± 1.252
2.972HisThr: 2.972 ± 1.044
0.849HisVal: 0.849 ± 0.424
0.425HisTrp: 0.425 ± 0.378
1.274HisTyr: 1.274 ± 0.334
0.0HisXaa: 0.0 ± 0.0
Ile
3.822IleAla: 3.822 ± 1.073
1.699IleCys: 1.699 ± 0.894
3.822IleAsp: 3.822 ± 0.958
3.397IleGlu: 3.397 ± 0.318
2.972IlePhe: 2.972 ± 0.991
3.397IleGly: 3.397 ± 0.609
0.849IleHis: 0.849 ± 0.596
2.123IleIle: 2.123 ± 0.437
2.123IleLys: 2.123 ± 1.11
2.548IleLeu: 2.548 ± 0.61
0.0IleMet: 0.0 ± 0.0
1.274IleAsn: 1.274 ± 0.334
4.246IlePro: 4.246 ± 2.534
1.699IleGln: 1.699 ± 0.573
2.548IleArg: 2.548 ± 0.856
4.671IleSer: 4.671 ± 1.36
1.699IleThr: 1.699 ± 0.206
2.123IleVal: 2.123 ± 0.712
0.849IleTrp: 0.849 ± 0.573
2.548IleTyr: 2.548 ± 0.61
0.0IleXaa: 0.0 ± 0.0
Lys
3.397LysAla: 3.397 ± 0.55
1.274LysCys: 1.274 ± 0.446
1.274LysAsp: 1.274 ± 0.446
3.822LysGlu: 3.822 ± 0.989
3.397LysPhe: 3.397 ± 1.189
2.548LysGly: 2.548 ± 0.964
1.274LysHis: 1.274 ± 0.694
2.972LysIle: 2.972 ± 0.738
5.096LysLys: 5.096 ± 2.342
1.699LysLeu: 1.699 ± 1.128
1.699LysMet: 1.699 ± 1.023
1.699LysAsn: 1.699 ± 0.848
2.972LysPro: 2.972 ± 1.642
1.274LysGln: 1.274 ± 0.672
4.671LysArg: 4.671 ± 0.966
2.972LysSer: 2.972 ± 1.291
3.397LysThr: 3.397 ± 1.115
2.548LysVal: 2.548 ± 0.971
0.849LysTrp: 0.849 ± 0.74
2.972LysTyr: 2.972 ± 0.372
0.0LysXaa: 0.0 ± 0.0
Leu
3.397LeuAla: 3.397 ± 0.74
2.123LeuCys: 2.123 ± 1.161
4.671LeuAsp: 4.671 ± 1.231
5.945LeuGlu: 5.945 ± 1.53
6.794LeuPhe: 6.794 ± 1.959
5.945LeuGly: 5.945 ± 2.681
2.123LeuHis: 2.123 ± 1.144
5.945LeuIle: 5.945 ± 1.767
3.397LeuLys: 3.397 ± 1.115
7.219LeuLeu: 7.219 ± 2.617
1.699LeuMet: 1.699 ± 0.663
3.822LeuAsn: 3.822 ± 1.838
6.794LeuPro: 6.794 ± 2.388
4.246LeuGln: 4.246 ± 0.795
6.369LeuArg: 6.369 ± 1.458
5.096LeuSer: 5.096 ± 2.998
6.369LeuThr: 6.369 ± 2.335
4.246LeuVal: 4.246 ± 0.86
0.425LeuTrp: 0.425 ± 0.412
3.822LeuTyr: 3.822 ± 1.26
0.0LeuXaa: 0.0 ± 0.0
Met
0.849MetAla: 0.849 ± 0.756
0.0MetCys: 0.0 ± 0.0
0.425MetAsp: 0.425 ± 0.412
1.699MetGlu: 1.699 ± 0.628
0.425MetPhe: 0.425 ± 0.378
0.425MetGly: 0.425 ± 0.37
0.849MetHis: 0.849 ± 0.624
0.849MetIle: 0.849 ± 0.424
1.274MetLys: 1.274 ± 0.694
1.274MetLeu: 1.274 ± 0.445
0.425MetMet: 0.425 ± 0.378
1.274MetAsn: 1.274 ± 0.713
0.425MetPro: 0.425 ± 0.519
0.0MetGln: 0.0 ± 0.0
0.849MetArg: 0.849 ± 0.824
1.699MetSer: 1.699 ± 0.848
0.849MetThr: 0.849 ± 0.429
1.274MetVal: 1.274 ± 0.7
0.0MetTrp: 0.0 ± 0.0
0.425MetTyr: 0.425 ± 0.37
0.0MetXaa: 0.0 ± 0.0
Asn
1.699AsnAla: 1.699 ± 0.725
0.849AsnCys: 0.849 ± 0.74
2.548AsnAsp: 2.548 ± 1.24
2.123AsnGlu: 2.123 ± 1.097
1.274AsnPhe: 1.274 ± 0.334
1.274AsnGly: 1.274 ± 0.713
0.849AsnHis: 0.849 ± 0.424
1.699AsnIle: 1.699 ± 0.858
2.548AsnLys: 2.548 ± 0.856
5.096AsnLeu: 5.096 ± 1.376
0.0AsnMet: 0.0 ± 0.0
2.548AsnAsn: 2.548 ± 1.272
2.548AsnPro: 2.548 ± 1.457
0.425AsnGln: 0.425 ± 0.378
2.123AsnArg: 2.123 ± 0.767
5.52AsnSer: 5.52 ± 2.411
2.123AsnThr: 2.123 ± 0.656
3.397AsnVal: 3.397 ± 1.151
0.849AsnTrp: 0.849 ± 0.424
2.548AsnTyr: 2.548 ± 0.859
0.0AsnXaa: 0.0 ± 0.0
Pro
5.945ProAla: 5.945 ± 2.643
0.425ProCys: 0.425 ± 0.529
4.246ProAsp: 4.246 ± 1.991
2.972ProGlu: 2.972 ± 0.876
2.548ProPhe: 2.548 ± 0.673
2.548ProGly: 2.548 ± 0.773
0.849ProHis: 0.849 ± 0.483
2.548ProIle: 2.548 ± 1.457
3.822ProLys: 3.822 ± 0.667
6.794ProLeu: 6.794 ± 0.976
0.0ProMet: 0.0 ± 0.0
3.397ProAsn: 3.397 ± 1.58
7.219ProPro: 7.219 ± 1.265
2.548ProGln: 2.548 ± 0.598
5.945ProArg: 5.945 ± 1.772
5.52ProSer: 5.52 ± 1.925
1.699ProThr: 1.699 ± 0.967
3.397ProVal: 3.397 ± 1.692
0.425ProTrp: 0.425 ± 0.412
2.123ProTyr: 2.123 ± 1.177
0.0ProXaa: 0.0 ± 0.0
Gln
1.699GlnAla: 1.699 ± 0.63
0.425GlnCys: 0.425 ± 0.37
1.274GlnAsp: 1.274 ± 0.445
4.246GlnGlu: 4.246 ± 1.006
0.849GlnPhe: 0.849 ± 0.424
1.699GlnGly: 1.699 ± 1.001
0.849GlnHis: 0.849 ± 0.624
2.123GlnIle: 2.123 ± 0.437
2.123GlnLys: 2.123 ± 0.401
5.096GlnLeu: 5.096 ± 1.031
1.699GlnMet: 1.699 ± 0.894
2.548GlnAsn: 2.548 ± 1.273
1.699GlnPro: 1.699 ± 0.579
4.671GlnGln: 4.671 ± 1.383
2.548GlnArg: 2.548 ± 1.657
2.123GlnSer: 2.123 ± 0.434
4.246GlnThr: 4.246 ± 1.607
1.274GlnVal: 1.274 ± 0.807
0.425GlnTrp: 0.425 ± 0.37
1.274GlnTyr: 1.274 ± 0.733
0.0GlnXaa: 0.0 ± 0.0
Arg
2.548ArgAla: 2.548 ± 1.453
0.849ArgCys: 0.849 ± 0.77
2.123ArgAsp: 2.123 ± 0.718
2.972ArgGlu: 2.972 ± 1.159
3.397ArgPhe: 3.397 ± 1.587
4.671ArgGly: 4.671 ± 1.236
2.972ArgHis: 2.972 ± 0.726
2.972ArgIle: 2.972 ± 0.53
2.548ArgLys: 2.548 ± 1.008
6.794ArgLeu: 6.794 ± 1.582
0.425ArgMet: 0.425 ± 0.412
1.699ArgAsn: 1.699 ± 0.455
5.096ArgPro: 5.096 ± 2.169
2.123ArgGln: 2.123 ± 1.588
4.246ArgArg: 4.246 ± 1.308
8.493ArgSer: 8.493 ± 1.624
2.123ArgThr: 2.123 ± 0.821
7.643ArgVal: 7.643 ± 1.508
0.0ArgTrp: 0.0 ± 0.0
3.397ArgTyr: 3.397 ± 1.401
0.0ArgXaa: 0.0 ± 0.0
Ser
5.52SerAla: 5.52 ± 1.162
1.699SerCys: 1.699 ± 0.865
6.369SerAsp: 6.369 ± 2.197
2.548SerGlu: 2.548 ± 0.897
4.671SerPhe: 4.671 ± 0.943
6.794SerGly: 6.794 ± 2.107
0.425SerHis: 0.425 ± 0.37
2.548SerIle: 2.548 ± 0.898
2.972SerLys: 2.972 ± 0.586
5.945SerLeu: 5.945 ± 1.129
0.425SerMet: 0.425 ± 0.451
2.972SerAsn: 2.972 ± 1.202
4.671SerPro: 4.671 ± 0.722
4.246SerGln: 4.246 ± 1.543
8.068SerArg: 8.068 ± 2.139
7.219SerSer: 7.219 ± 1.74
5.52SerThr: 5.52 ± 2.108
4.246SerVal: 4.246 ± 0.866
0.425SerTrp: 0.425 ± 0.37
0.849SerTyr: 0.849 ± 0.74
0.0SerXaa: 0.0 ± 0.0
Thr
3.822ThrAla: 3.822 ± 1.26
2.123ThrCys: 2.123 ± 1.092
3.822ThrAsp: 3.822 ± 1.989
0.849ThrGlu: 0.849 ± 0.429
3.822ThrPhe: 3.822 ± 1.28
3.397ThrGly: 3.397 ± 0.885
0.0ThrHis: 0.0 ± 0.0
2.123ThrIle: 2.123 ± 0.856
0.849ThrLys: 0.849 ± 0.495
5.52ThrLeu: 5.52 ± 1.563
1.274ThrMet: 1.274 ± 0.708
0.849ThrAsn: 0.849 ± 0.473
6.369ThrPro: 6.369 ± 1.462
0.849ThrGln: 0.849 ± 0.424
5.096ThrArg: 5.096 ± 0.957
5.945ThrSer: 5.945 ± 2.17
2.972ThrThr: 2.972 ± 1.746
3.397ThrVal: 3.397 ± 1.328
0.849ThrTrp: 0.849 ± 0.824
1.699ThrTyr: 1.699 ± 0.769
0.0ThrXaa: 0.0 ± 0.0
Val
2.548ValAla: 2.548 ± 0.537
1.699ValCys: 1.699 ± 1.584
4.246ValAsp: 4.246 ± 0.884
2.972ValGlu: 2.972 ± 0.598
2.972ValPhe: 2.972 ± 0.586
3.397ValGly: 3.397 ± 1.271
2.548ValHis: 2.548 ± 0.934
4.246ValIle: 4.246 ± 0.954
1.699ValLys: 1.699 ± 1.001
4.246ValLeu: 4.246 ± 0.692
0.849ValMet: 0.849 ± 0.74
1.699ValAsn: 1.699 ± 0.573
3.397ValPro: 3.397 ± 1.19
2.972ValGln: 2.972 ± 0.372
7.219ValArg: 7.219 ± 1.725
5.945ValSer: 5.945 ± 1.183
3.822ValThr: 3.822 ± 1.504
1.699ValVal: 1.699 ± 0.573
0.849ValTrp: 0.849 ± 0.756
1.699ValTyr: 1.699 ± 0.746
0.0ValXaa: 0.0 ± 0.0
Trp
1.274TrpAla: 1.274 ± 0.446
0.0TrpCys: 0.0 ± 0.0
0.425TrpAsp: 0.425 ± 0.378
0.425TrpGlu: 0.425 ± 0.529
0.425TrpPhe: 0.425 ± 0.37
1.699TrpGly: 1.699 ± 0.725
0.425TrpHis: 0.425 ± 0.378
1.274TrpIle: 1.274 ± 0.7
1.699TrpLys: 1.699 ± 1.117
0.849TrpLeu: 0.849 ± 0.424
0.425TrpMet: 0.425 ± 0.378
0.425TrpAsn: 0.425 ± 0.37
0.0TrpPro: 0.0 ± 0.0
0.849TrpGln: 0.849 ± 0.824
0.425TrpArg: 0.425 ± 0.412
0.0TrpSer: 0.0 ± 0.0
1.274TrpThr: 1.274 ± 1.236
1.274TrpVal: 1.274 ± 1.11
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.699TyrAla: 1.699 ± 0.725
0.425TyrCys: 0.425 ± 0.412
2.123TyrAsp: 2.123 ± 0.674
2.123TyrGlu: 2.123 ± 0.798
1.699TyrPhe: 1.699 ± 0.828
2.972TyrGly: 2.972 ± 1.111
0.425TyrHis: 0.425 ± 0.378
2.972TyrIle: 2.972 ± 1.052
1.699TyrLys: 1.699 ± 1.059
3.822TyrLeu: 3.822 ± 1.433
0.0TyrMet: 0.0 ± 0.0
0.849TyrAsn: 0.849 ± 0.74
2.123TyrPro: 2.123 ± 0.974
0.849TyrGln: 0.849 ± 0.495
1.699TyrArg: 1.699 ± 0.601
1.699TyrSer: 1.699 ± 0.675
1.274TyrThr: 1.274 ± 0.807
2.972TyrVal: 2.972 ± 1.368
1.699TyrTrp: 1.699 ± 0.613
1.274TyrTyr: 1.274 ± 1.236
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2356 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski