Amino acid dipepetide frequency for Lachnellula cervina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.465AlaAla: 8.465 ± 0.065	0.98AlaCys: 0.98 ± 0.015	3.996AlaAsp: 3.996 ± 0.033	4.994AlaGlu: 4.994 ± 0.041	3.219AlaPhe: 3.219 ± 0.03	5.961AlaGly: 5.961 ± 0.043	1.643AlaHis: 1.643 ± 0.018	4.509AlaIle: 4.509 ± 0.034	4.367AlaLys: 4.367 ± 0.036	7.694AlaLeu: 7.694 ± 0.046	1.905AlaMet: 1.905 ± 0.018	3.078AlaAsn: 3.078 ± 0.03	4.637AlaPro: 4.637 ± 0.044	3.182AlaGln: 3.182 ± 0.029	4.434AlaArg: 4.434 ± 0.034	7.341AlaSer: 7.341 ± 0.047	5.172AlaThr: 5.172 ± 0.037	5.262AlaVal: 5.262 ± 0.033	1.126AlaTrp: 1.126 ± 0.017	2.19AlaTyr: 2.19 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.866CysAla: 0.866 ± 0.015	0.203CysCys: 0.203 ± 0.007	0.588CysAsp: 0.588 ± 0.011	0.551CysGlu: 0.551 ± 0.011	0.541CysPhe: 0.541 ± 0.013	0.892CysGly: 0.892 ± 0.016	0.295CysHis: 0.295 ± 0.008	0.687CysIle: 0.687 ± 0.014	0.519CysLys: 0.519 ± 0.013	1.158CysLeu: 1.158 ± 0.018	0.256CysMet: 0.256 ± 0.007	0.416CysAsn: 0.416 ± 0.01	0.581CysPro: 0.581 ± 0.012	0.385CysGln: 0.385 ± 0.01	0.595CysArg: 0.595 ± 0.012	0.832CysSer: 0.832 ± 0.016	0.65CysThr: 0.65 ± 0.011	0.742CysVal: 0.742 ± 0.012	0.189CysTrp: 0.189 ± 0.007	0.336CysTyr: 0.336 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.481AspAla: 4.481 ± 0.035	0.586AspCys: 0.586 ± 0.013	3.88AspAsp: 3.88 ± 0.042	4.377AspGlu: 4.377 ± 0.044	2.34AspPhe: 2.34 ± 0.027	4.041AspGly: 4.041 ± 0.03	1.113AspHis: 1.113 ± 0.016	3.185AspIle: 3.185 ± 0.028	2.414AspLys: 2.414 ± 0.025	4.993AspLeu: 4.993 ± 0.04	1.247AspMet: 1.247 ± 0.019	1.888AspAsn: 1.888 ± 0.022	3.111AspPro: 3.111 ± 0.027	1.737AspGln: 1.737 ± 0.02	2.687AspArg: 2.687 ± 0.028	4.074AspSer: 4.074 ± 0.033	2.888AspThr: 2.888 ± 0.026	3.633AspVal: 3.633 ± 0.031	0.843AspTrp: 0.843 ± 0.015	1.583AspTyr: 1.583 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.29GluAla: 5.29 ± 0.041	0.57GluCys: 0.57 ± 0.011	4.212GluAsp: 4.212 ± 0.039	5.573GluGlu: 5.573 ± 0.056	2.017GluPhe: 2.017 ± 0.021	4.072GluGly: 4.072 ± 0.035	1.33GluHis: 1.33 ± 0.016	3.247GluIle: 3.247 ± 0.029	4.115GluLys: 4.115 ± 0.038	5.141GluLeu: 5.141 ± 0.042	1.512GluMet: 1.512 ± 0.018	2.457GluAsn: 2.457 ± 0.026	2.579GluPro: 2.579 ± 0.027	2.276GluGln: 2.276 ± 0.024	3.765GluArg: 3.765 ± 0.042	4.298GluSer: 4.298 ± 0.032	3.416GluThr: 3.416 ± 0.029	3.774GluVal: 3.774 ± 0.036	0.892GluTrp: 0.892 ± 0.014	1.704GluTyr: 1.704 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.153PheAla: 3.153 ± 0.029	0.554PheCys: 0.554 ± 0.012	2.32PheAsp: 2.32 ± 0.022	2.288PheGlu: 2.288 ± 0.023	1.665PhePhe: 1.665 ± 0.026	3.045PheGly: 3.045 ± 0.033	0.866PheHis: 0.866 ± 0.013	1.921PheIle: 1.921 ± 0.022	1.704PheLys: 1.704 ± 0.023	3.592PheLeu: 3.592 ± 0.03	0.824PheMet: 0.824 ± 0.013	1.547PheAsn: 1.547 ± 0.019	1.992PhePro: 1.992 ± 0.024	1.455PheGln: 1.455 ± 0.017	1.833PheArg: 1.833 ± 0.019	3.144PheSer: 3.144 ± 0.027	2.265PheThr: 2.265 ± 0.022	2.468PheVal: 2.468 ± 0.024	0.663PheTrp: 0.663 ± 0.012	1.152PheTyr: 1.152 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.501GlyAla: 5.501 ± 0.039	0.827GlyCys: 0.827 ± 0.014	3.651GlyAsp: 3.651 ± 0.031	3.916GlyGlu: 3.916 ± 0.033	3.048GlyPhe: 3.048 ± 0.029	6.328GlyGly: 6.328 ± 0.066	1.624GlyHis: 1.624 ± 0.021	3.86GlyIle: 3.86 ± 0.031	3.962GlyLys: 3.962 ± 0.039	6.205GlyLeu: 6.205 ± 0.039	1.764GlyMet: 1.764 ± 0.021	2.797GlyAsn: 2.797 ± 0.029	3.261GlyPro: 3.261 ± 0.032	2.419GlyGln: 2.419 ± 0.024	3.97GlyArg: 3.97 ± 0.036	5.889GlySer: 5.889 ± 0.045	4.178GlyThr: 4.178 ± 0.034	4.653GlyVal: 4.653 ± 0.036	1.186GlyTrp: 1.186 ± 0.018	2.18GlyTyr: 2.18 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.68HisAla: 1.68 ± 0.019	0.297HisCys: 0.297 ± 0.009	1.184HisAsp: 1.184 ± 0.018	1.26HisGlu: 1.26 ± 0.017	0.906HisPhe: 0.906 ± 0.016	1.6HisGly: 1.6 ± 0.02	0.77HisHis: 0.77 ± 0.018	1.2HisIle: 1.2 ± 0.016	0.988HisLys: 0.988 ± 0.015	2.129HisLeu: 2.129 ± 0.023	0.467HisMet: 0.467 ± 0.009	0.897HisAsn: 0.897 ± 0.015	1.546HisPro: 1.546 ± 0.019	0.913HisGln: 0.913 ± 0.015	1.323HisArg: 1.323 ± 0.016	1.773HisSer: 1.773 ± 0.021	1.25HisThr: 1.25 ± 0.018	1.336HisVal: 1.336 ± 0.018	0.32HisTrp: 0.32 ± 0.008	0.673HisTyr: 0.673 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.485IleAla: 4.485 ± 0.036	0.747IleCys: 0.747 ± 0.015	2.973IleAsp: 2.973 ± 0.027	3.065IleGlu: 3.065 ± 0.029	2.143IlePhe: 2.143 ± 0.022	3.509IleGly: 3.509 ± 0.035	1.215IleHis: 1.215 ± 0.017	2.862IleIle: 2.862 ± 0.03	2.519IleLys: 2.519 ± 0.028	4.86IleLeu: 4.86 ± 0.037	1.09IleMet: 1.09 ± 0.016	1.974IleAsn: 1.974 ± 0.02	3.229IlePro: 3.229 ± 0.024	1.957IleGln: 1.957 ± 0.022	2.689IleArg: 2.689 ± 0.025	4.263IleSer: 4.263 ± 0.035	3.104IleThr: 3.104 ± 0.027	3.306IleVal: 3.306 ± 0.028	0.759IleTrp: 0.759 ± 0.013	1.525IleTyr: 1.525 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	4.685LysAla: 4.685 ± 0.033	0.489LysCys: 0.489 ± 0.011	3.095LysAsp: 3.095 ± 0.031	3.805LysGlu: 3.805 ± 0.036	1.636LysPhe: 1.636 ± 0.018	3.468LysGly: 3.468 ± 0.032	1.176LysHis: 1.176 ± 0.017	2.598LysIle: 2.598 ± 0.025	3.813LysLys: 3.813 ± 0.051	4.416LysLeu: 4.416 ± 0.039	1.117LysMet: 1.117 ± 0.015	1.983LysAsn: 1.983 ± 0.02	2.913LysPro: 2.913 ± 0.029	1.891LysGln: 1.891 ± 0.023	3.393LysArg: 3.393 ± 0.034	3.996LysSer: 3.996 ± 0.039	3.159LysThr: 3.159 ± 0.027	3.137LysVal: 3.137 ± 0.026	0.72LysTrp: 0.72 ± 0.012	1.503LysTyr: 1.503 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	7.627LeuAla: 7.627 ± 0.048	1.135LeuCys: 1.135 ± 0.018	5.075LeuAsp: 5.075 ± 0.042	5.582LeuGlu: 5.582 ± 0.044	3.395LeuPhe: 3.395 ± 0.031	6.119LeuGly: 6.119 ± 0.041	2.116LeuHis: 2.116 ± 0.022	4.215LeuIle: 4.215 ± 0.037	4.672LeuLys: 4.672 ± 0.035	8.4LeuLeu: 8.4 ± 0.061	1.809LeuMet: 1.809 ± 0.019	3.326LeuAsn: 3.326 ± 0.027	5.432LeuPro: 5.432 ± 0.036	3.707LeuGln: 3.707 ± 0.033	5.232LeuArg: 5.232 ± 0.034	7.3LeuSer: 7.3 ± 0.047	4.867LeuThr: 4.867 ± 0.037	5.336LeuVal: 5.336 ± 0.036	1.161LeuTrp: 1.161 ± 0.017	2.373LeuTyr: 2.373 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.207MetAla: 2.207 ± 0.023	0.237MetCys: 0.237 ± 0.007	1.254MetAsp: 1.254 ± 0.018	1.303MetGlu: 1.303 ± 0.02	0.802MetPhe: 0.802 ± 0.013	1.608MetGly: 1.608 ± 0.021	0.47MetHis: 0.47 ± 0.011	1.054MetIle: 1.054 ± 0.016	1.126MetLys: 1.126 ± 0.017	1.843MetLeu: 1.843 ± 0.02	0.591MetMet: 0.591 ± 0.012	0.849MetAsn: 0.849 ± 0.015	1.231MetPro: 1.231 ± 0.018	0.865MetGln: 0.865 ± 0.016	1.182MetArg: 1.182 ± 0.015	1.93MetSer: 1.93 ± 0.022	1.275MetThr: 1.275 ± 0.016	1.306MetVal: 1.306 ± 0.016	0.263MetTrp: 0.263 ± 0.007	0.527MetTyr: 0.527 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.222AsnAla: 3.222 ± 0.03	0.441AsnCys: 0.441 ± 0.011	1.954AsnAsp: 1.954 ± 0.023	2.082AsnGlu: 2.082 ± 0.021	1.513AsnPhe: 1.513 ± 0.022	3.326AsnGly: 3.326 ± 0.03	0.874AsnHis: 0.874 ± 0.016	2.285AsnIle: 2.285 ± 0.023	1.749AsnLys: 1.749 ± 0.022	3.438AsnLeu: 3.438 ± 0.03	0.883AsnMet: 0.883 ± 0.015	1.634AsnAsn: 1.634 ± 0.025	2.544AsnPro: 2.544 ± 0.026	1.358AsnGln: 1.358 ± 0.021	1.857AsnArg: 1.857 ± 0.018	3.117AsnSer: 3.117 ± 0.031	2.502AsnThr: 2.502 ± 0.024	2.382AsnVal: 2.382 ± 0.022	0.562AsnTrp: 0.562 ± 0.012	1.118AsnTyr: 1.118 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.882ProAla: 4.882 ± 0.042	0.437ProCys: 0.437 ± 0.011	2.885ProAsp: 2.885 ± 0.027	3.691ProGlu: 3.691 ± 0.032	2.052ProPhe: 2.052 ± 0.022	3.758ProGly: 3.758 ± 0.033	1.268ProHis: 1.268 ± 0.015	2.791ProIle: 2.791 ± 0.023	3.005ProLys: 3.005 ± 0.027	4.68ProLeu: 4.68 ± 0.032	1.044ProMet: 1.044 ± 0.015	2.317ProAsn: 2.317 ± 0.025	4.865ProPro: 4.865 ± 0.064	2.439ProGln: 2.439 ± 0.031	3.099ProArg: 3.099 ± 0.031	5.797ProSer: 5.797 ± 0.045	4.008ProThr: 4.008 ± 0.03	3.382ProVal: 3.382 ± 0.029	0.683ProTrp: 0.683 ± 0.012	1.522ProTyr: 1.522 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.269GlnAla: 3.269 ± 0.032	0.403GlnCys: 0.403 ± 0.01	1.956GlnAsp: 1.956 ± 0.022	2.349GlnGlu: 2.349 ± 0.025	1.288GlnPhe: 1.288 ± 0.015	2.358GlnGly: 2.358 ± 0.027	0.997GlnHis: 0.997 ± 0.016	1.936GlnIle: 1.936 ± 0.022	2.119GlnLys: 2.119 ± 0.023	3.221GlnLeu: 3.221 ± 0.029	0.872GlnMet: 0.872 ± 0.015	1.671GlnAsn: 1.671 ± 0.022	2.202GlnPro: 2.202 ± 0.027	2.157GlnGln: 2.157 ± 0.046	2.392GlnArg: 2.392 ± 0.029	3.079GlnSer: 3.079 ± 0.031	2.304GlnThr: 2.304 ± 0.023	2.073GlnVal: 2.073 ± 0.023	0.552GlnTrp: 0.552 ± 0.012	1.19GlnTyr: 1.19 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.251ArgAla: 4.251 ± 0.034	0.58ArgCys: 0.58 ± 0.012	3.09ArgAsp: 3.09 ± 0.029	3.609ArgGlu: 3.609 ± 0.038	2.016ArgPhe: 2.016 ± 0.021	3.704ArgGly: 3.704 ± 0.036	1.325ArgHis: 1.325 ± 0.016	2.824ArgIle: 2.824 ± 0.023	3.496ArgLys: 3.496 ± 0.033	4.885ArgLeu: 4.885 ± 0.037	1.246ArgMet: 1.246 ± 0.015	2.247ArgAsn: 2.247 ± 0.026	3.107ArgPro: 3.107 ± 0.028	2.313ArgGln: 2.313 ± 0.03	4.33ArgArg: 4.33 ± 0.049	4.435ArgSer: 4.435 ± 0.042	3.057ArgThr: 3.057 ± 0.028	3.084ArgVal: 3.084 ± 0.025	0.84ArgTrp: 0.84 ± 0.014	1.518ArgTyr: 1.518 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.59SerAla: 6.59 ± 0.048	0.804SerCys: 0.804 ± 0.017	4.083SerAsp: 4.083 ± 0.032	4.207SerGlu: 4.207 ± 0.031	3.142SerPhe: 3.142 ± 0.032	5.772SerGly: 5.772 ± 0.042	1.836SerHis: 1.836 ± 0.02	4.421SerIle: 4.421 ± 0.034	4.267SerLys: 4.267 ± 0.035	7.207SerLeu: 7.207 ± 0.045	1.777SerMet: 1.777 ± 0.019	3.348SerAsn: 3.348 ± 0.035	5.5SerPro: 5.5 ± 0.048	3.256SerGln: 3.256 ± 0.031	4.729SerArg: 4.729 ± 0.04	9.049SerSer: 9.049 ± 0.08	5.892SerThr: 5.892 ± 0.041	4.52SerVal: 4.52 ± 0.034	1.096SerTrp: 1.096 ± 0.016	2.209SerTyr: 2.209 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.142ThrAla: 5.142 ± 0.034	0.667ThrCys: 0.667 ± 0.015	2.749ThrAsp: 2.749 ± 0.023	3.07ThrGlu: 3.07 ± 0.025	2.402ThrPhe: 2.402 ± 0.024	4.283ThrGly: 4.283 ± 0.038	1.268ThrHis: 1.268 ± 0.017	3.342ThrIle: 3.342 ± 0.029	2.902ThrLys: 2.902 ± 0.029	5.396ThrLeu: 5.396 ± 0.041	1.19ThrMet: 1.19 ± 0.016	2.336ThrAsn: 2.336 ± 0.025	4.43ThrPro: 4.43 ± 0.042	2.12ThrGln: 2.12 ± 0.022	2.963ThrArg: 2.963 ± 0.027	5.648ThrSer: 5.648 ± 0.041	4.319ThrThr: 4.319 ± 0.037	3.597ThrVal: 3.597 ± 0.032	0.831ThrTrp: 0.831 ± 0.013	1.691ThrTyr: 1.691 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.081ValAla: 5.081 ± 0.041	0.742ValCys: 0.742 ± 0.013	3.656ValAsp: 3.656 ± 0.031	4.031ValGlu: 4.031 ± 0.03	2.524ValPhe: 2.524 ± 0.026	4.247ValGly: 4.247 ± 0.035	1.289ValHis: 1.289 ± 0.016	3.035ValIle: 3.035 ± 0.026	3.204ValLys: 3.204 ± 0.026	5.624ValLeu: 5.624 ± 0.04	1.344ValMet: 1.344 ± 0.017	2.254ValAsn: 2.254 ± 0.026	3.427ValPro: 3.427 ± 0.028	2.296ValGln: 2.296 ± 0.025	3.128ValArg: 3.128 ± 0.028	4.557ValSer: 4.557 ± 0.034	3.413ValThr: 3.413 ± 0.029	4.351ValVal: 4.351 ± 0.037	0.854ValTrp: 0.854 ± 0.014	1.736ValTyr: 1.736 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.1TrpAla: 1.1 ± 0.017	0.182TrpCys: 0.182 ± 0.007	0.891TrpAsp: 0.891 ± 0.016	0.851TrpGlu: 0.851 ± 0.014	0.537TrpPhe: 0.537 ± 0.01	0.97TrpGly: 0.97 ± 0.017	0.333TrpHis: 0.333 ± 0.01	0.786TrpIle: 0.786 ± 0.015	0.806TrpLys: 0.806 ± 0.014	1.291TrpLeu: 1.291 ± 0.019	0.368TrpMet: 0.368 ± 0.01	0.644TrpAsn: 0.644 ± 0.01	0.562TrpPro: 0.562 ± 0.013	0.552TrpGln: 0.552 ± 0.013	0.871TrpArg: 0.871 ± 0.015	1.031TrpSer: 1.031 ± 0.016	0.904TrpThr: 0.904 ± 0.014	0.864TrpVal: 0.864 ± 0.013	0.269TrpTrp: 0.269 ± 0.008	0.427TrpTyr: 0.427 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.179TyrAla: 2.179 ± 0.023	0.401TyrCys: 0.401 ± 0.01	1.61TyrAsp: 1.61 ± 0.02	1.634TyrGlu: 1.634 ± 0.021	1.263TyrPhe: 1.263 ± 0.019	2.158TyrGly: 2.158 ± 0.025	0.705TyrHis: 0.705 ± 0.012	1.516TyrIle: 1.516 ± 0.021	1.248TyrLys: 1.248 ± 0.018	2.707TyrLeu: 2.707 ± 0.026	0.616TyrMet: 0.616 ± 0.011	1.177TyrAsn: 1.177 ± 0.016	1.456TyrPro: 1.456 ± 0.02	1.108TyrGln: 1.108 ± 0.018	1.486TyrArg: 1.486 ± 0.019	2.151TyrSer: 2.151 ± 0.021	1.722TyrThr: 1.722 ± 0.019	1.59TyrVal: 1.59 ± 0.02	0.429TyrTrp: 0.429 ± 0.011	0.95TyrTyr: 0.95 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9411 proteins (4670120 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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