Amino acid dipepetide frequency for Red clover cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.703AlaAla: 12.703 ± 5.195
0.0AlaCys: 0.0 ± 0.0
3.529AlaAsp: 3.529 ± 0.597
2.823AlaGlu: 2.823 ± 1.049
1.411AlaPhe: 1.411 ± 1.0
2.117AlaGly: 2.117 ± 0.549
3.529AlaHis: 3.529 ± 0.597
2.823AlaIle: 2.823 ± 0.097
2.117AlaLys: 2.117 ± 0.403
4.94AlaLeu: 4.94 ± 2.549
0.706AlaMet: 0.706 ± 0.452
3.529AlaAsn: 3.529 ± 1.549
8.469AlaPro: 8.469 ± 0.29
2.117AlaGln: 2.117 ± 0.403
6.351AlaArg: 6.351 ± 1.21
3.529AlaSer: 3.529 ± 0.597
7.057AlaThr: 7.057 ± 1.194
2.823AlaVal: 2.823 ± 1.049
0.0AlaTrp: 0.0 ± 0.0
4.94AlaTyr: 4.94 ± 0.645
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.706CysCys: 0.706 ± 0.452
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.706CysPhe: 0.706 ± 0.5
0.706CysGly: 0.706 ± 0.452
0.706CysHis: 0.706 ± 0.452
0.706CysIle: 0.706 ± 0.452
0.706CysLys: 0.706 ± 0.452
0.706CysLeu: 0.706 ± 0.5
2.117CysMet: 2.117 ± 1.501
0.706CysAsn: 0.706 ± 0.452
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.706CysArg: 0.706 ± 0.452
0.0CysSer: 0.0 ± 0.0
0.706CysThr: 0.706 ± 0.5
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.706CysTyr: 0.706 ± 0.452
0.0CysXaa: 0.0 ± 0.0
Asp
8.469AspAla: 8.469 ± 0.29
0.706AspCys: 0.706 ± 0.5
3.529AspAsp: 3.529 ± 1.307
2.117AspGlu: 2.117 ± 0.403
2.823AspPhe: 2.823 ± 0.855
2.823AspGly: 2.823 ± 0.855
1.411AspHis: 1.411 ± 0.048
2.823AspIle: 2.823 ± 0.097
0.0AspLys: 0.0 ± 0.0
4.94AspLeu: 4.94 ± 0.307
0.0AspMet: 0.0 ± 0.0
4.94AspAsn: 4.94 ± 0.307
4.234AspPro: 4.234 ± 2.711
2.823AspGln: 2.823 ± 1.049
3.529AspArg: 3.529 ± 0.597
3.529AspSer: 3.529 ± 0.597
4.234AspThr: 4.234 ± 1.097
4.234AspVal: 4.234 ± 0.145
0.706AspTrp: 0.706 ± 0.452
6.351AspTyr: 6.351 ± 0.694
0.0AspXaa: 0.0 ± 0.0
Glu
2.117GluAla: 2.117 ± 0.403
0.0GluCys: 0.0 ± 0.0
5.646GluAsp: 5.646 ± 0.193
1.411GluGlu: 1.411 ± 0.048
1.411GluPhe: 1.411 ± 0.048
0.0GluGly: 0.0 ± 0.0
0.706GluHis: 0.706 ± 0.452
2.117GluIle: 2.117 ± 0.403
1.411GluLys: 1.411 ± 0.904
4.234GluLeu: 4.234 ± 0.145
0.706GluMet: 0.706 ± 0.5
2.117GluAsn: 2.117 ± 1.355
0.0GluPro: 0.0 ± 0.0
2.117GluGln: 2.117 ± 1.355
2.823GluArg: 2.823 ± 1.807
6.351GluSer: 6.351 ± 1.646
2.823GluThr: 2.823 ± 0.855
1.411GluVal: 1.411 ± 0.904
0.0GluTrp: 0.0 ± 0.0
3.529GluTyr: 3.529 ± 2.259
0.0GluXaa: 0.0 ± 0.0
Phe
2.117PheAla: 2.117 ± 0.549
1.411PheCys: 1.411 ± 0.904
2.117PheAsp: 2.117 ± 0.549
1.411PheGlu: 1.411 ± 0.048
2.117PhePhe: 2.117 ± 0.549
4.234PheGly: 4.234 ± 0.807
2.117PheHis: 2.117 ± 0.549
4.234PheIle: 4.234 ± 1.759
2.117PheLys: 2.117 ± 0.403
7.763PheLeu: 7.763 ± 0.742
0.706PheMet: 0.706 ± 0.5
5.646PheAsn: 5.646 ± 0.193
4.234PhePro: 4.234 ± 0.145
1.411PheGln: 1.411 ± 0.048
2.117PheArg: 2.117 ± 0.549
3.529PheSer: 3.529 ± 0.597
3.529PheThr: 3.529 ± 1.549
2.117PheVal: 2.117 ± 0.403
0.0PheTrp: 0.0 ± 0.0
1.411PheTyr: 1.411 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
1.411GlyAsp: 1.411 ± 0.048
0.706GlyGlu: 0.706 ± 0.452
3.529GlyPhe: 3.529 ± 1.549
0.706GlyGly: 0.706 ± 0.5
0.706GlyHis: 0.706 ± 0.452
2.117GlyIle: 2.117 ± 0.403
1.411GlyLys: 1.411 ± 1.0
3.529GlyLeu: 3.529 ± 2.259
2.117GlyMet: 2.117 ± 0.549
2.117GlyAsn: 2.117 ± 0.549
0.706GlyPro: 0.706 ± 0.452
0.706GlyGln: 0.706 ± 0.452
0.706GlyArg: 0.706 ± 0.5
3.529GlySer: 3.529 ± 0.597
3.529GlyThr: 3.529 ± 0.355
0.706GlyVal: 0.706 ± 0.452
0.0GlyTrp: 0.0 ± 0.0
6.351GlyTyr: 6.351 ± 1.21
0.0GlyXaa: 0.0 ± 0.0
His
4.234HisAla: 4.234 ± 2.049
0.706HisCys: 0.706 ± 0.452
4.234HisAsp: 4.234 ± 1.097
0.0HisGlu: 0.0 ± 0.0
2.823HisPhe: 2.823 ± 1.807
2.117HisGly: 2.117 ± 0.403
0.706HisHis: 0.706 ± 0.5
4.234HisIle: 4.234 ± 0.145
0.706HisLys: 0.706 ± 0.452
0.706HisLeu: 0.706 ± 0.5
0.706HisMet: 0.706 ± 0.452
2.117HisAsn: 2.117 ± 1.355
0.706HisPro: 0.706 ± 0.5
1.411HisGln: 1.411 ± 0.904
0.706HisArg: 0.706 ± 0.452
0.706HisSer: 0.706 ± 0.452
4.234HisThr: 4.234 ± 1.097
0.706HisVal: 0.706 ± 0.5
0.0HisTrp: 0.0 ± 0.0
2.823HisTyr: 2.823 ± 0.097
0.0HisXaa: 0.0 ± 0.0
Ile
2.117IleAla: 2.117 ± 0.549
0.706IleCys: 0.706 ± 0.5
3.529IleAsp: 3.529 ± 1.307
4.94IleGlu: 4.94 ± 1.259
3.529IlePhe: 3.529 ± 1.549
2.823IleGly: 2.823 ± 0.855
1.411IleHis: 1.411 ± 1.0
3.529IleIle: 3.529 ± 0.355
2.117IleLys: 2.117 ± 0.403
3.529IleLeu: 3.529 ± 0.355
1.411IleMet: 1.411 ± 0.048
3.529IleAsn: 3.529 ± 1.307
5.646IlePro: 5.646 ± 0.759
0.706IleGln: 0.706 ± 0.5
2.823IleArg: 2.823 ± 0.855
2.823IleSer: 2.823 ± 1.807
4.234IleThr: 4.234 ± 2.049
3.529IleVal: 3.529 ± 0.355
0.706IleTrp: 0.706 ± 0.5
3.529IleTyr: 3.529 ± 1.307
0.0IleXaa: 0.0 ± 0.0
Lys
0.706LysAla: 0.706 ± 0.452
0.0LysCys: 0.0 ± 0.0
0.706LysAsp: 0.706 ± 0.5
2.117LysGlu: 2.117 ± 1.355
2.823LysPhe: 2.823 ± 1.049
0.706LysGly: 0.706 ± 0.452
2.117LysHis: 2.117 ± 0.403
0.706LysIle: 0.706 ± 0.452
0.0LysLys: 0.0 ± 0.0
2.823LysLeu: 2.823 ± 1.807
0.0LysMet: 0.0 ± 0.0
2.117LysAsn: 2.117 ± 0.549
2.117LysPro: 2.117 ± 0.403
2.823LysGln: 2.823 ± 1.807
2.117LysArg: 2.117 ± 1.355
3.529LysSer: 3.529 ± 0.597
2.823LysThr: 2.823 ± 0.855
4.234LysVal: 4.234 ± 1.097
0.706LysTrp: 0.706 ± 0.452
2.823LysTyr: 2.823 ± 0.855
0.0LysXaa: 0.0 ± 0.0
Leu
3.529LeuAla: 3.529 ± 0.355
1.411LeuCys: 1.411 ± 0.048
6.351LeuAsp: 6.351 ± 0.258
3.529LeuGlu: 3.529 ± 2.259
3.529LeuPhe: 3.529 ± 1.307
3.529LeuGly: 3.529 ± 0.597
3.529LeuHis: 3.529 ± 0.355
4.94LeuIle: 4.94 ± 0.307
3.529LeuLys: 3.529 ± 1.307
4.94LeuLeu: 4.94 ± 0.645
3.529LeuMet: 3.529 ± 0.355
3.529LeuAsn: 3.529 ± 0.597
9.88LeuPro: 9.88 ± 3.195
2.117LeuGln: 2.117 ± 0.549
5.646LeuArg: 5.646 ± 2.098
3.529LeuSer: 3.529 ± 0.355
5.646LeuThr: 5.646 ± 0.193
7.057LeuVal: 7.057 ± 0.71
0.706LeuTrp: 0.706 ± 0.5
4.94LeuTyr: 4.94 ± 0.307
0.0LeuXaa: 0.0 ± 0.0
Met
0.706MetAla: 0.706 ± 0.452
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.706MetGlu: 0.706 ± 0.5
3.529MetPhe: 3.529 ± 1.549
0.0MetGly: 0.0 ± 0.0
0.706MetHis: 0.706 ± 0.5
2.117MetIle: 2.117 ± 0.549
0.0MetLys: 0.0 ± 0.0
1.411MetLeu: 1.411 ± 0.904
0.0MetMet: 0.0 ± 0.0
2.823MetAsn: 2.823 ± 1.049
1.411MetPro: 1.411 ± 0.048
0.706MetGln: 0.706 ± 0.5
0.706MetArg: 0.706 ± 0.452
0.706MetSer: 0.706 ± 0.5
2.823MetThr: 2.823 ± 0.855
0.706MetVal: 0.706 ± 0.452
0.0MetTrp: 0.0 ± 0.0
2.823MetTyr: 2.823 ± 0.855
0.0MetXaa: 0.0 ± 0.0
Asn
3.529AsnAla: 3.529 ± 0.597
0.706AsnCys: 0.706 ± 0.5
4.234AsnAsp: 4.234 ± 0.807
2.823AsnGlu: 2.823 ± 1.049
4.234AsnPhe: 4.234 ± 0.807
1.411AsnGly: 1.411 ± 0.048
4.234AsnHis: 4.234 ± 0.807
0.706AsnIle: 0.706 ± 0.452
2.117AsnLys: 2.117 ± 1.355
9.88AsnLeu: 9.88 ± 1.291
2.117AsnMet: 2.117 ± 0.403
1.411AsnAsn: 1.411 ± 0.904
2.117AsnPro: 2.117 ± 0.549
0.706AsnGln: 0.706 ± 0.5
2.117AsnArg: 2.117 ± 0.549
3.529AsnSer: 3.529 ± 0.597
4.94AsnThr: 4.94 ± 0.307
2.823AsnVal: 2.823 ± 1.049
0.0AsnTrp: 0.0 ± 0.0
2.823AsnTyr: 2.823 ± 0.097
0.0AsnXaa: 0.0 ± 0.0
Pro
5.646ProAla: 5.646 ± 2.098
0.0ProCys: 0.0 ± 0.0
7.057ProAsp: 7.057 ± 0.71
4.94ProGlu: 4.94 ± 2.211
2.823ProPhe: 2.823 ± 0.855
4.94ProGly: 4.94 ± 2.549
2.117ProHis: 2.117 ± 0.403
4.94ProIle: 4.94 ± 0.307
2.117ProLys: 2.117 ± 1.355
4.234ProLeu: 4.234 ± 1.759
2.117ProMet: 2.117 ± 0.313
2.117ProAsn: 2.117 ± 1.501
3.529ProPro: 3.529 ± 0.597
0.706ProGln: 0.706 ± 0.5
3.529ProArg: 3.529 ± 1.549
5.646ProSer: 5.646 ± 1.711
9.88ProThr: 9.88 ± 0.339
4.94ProVal: 4.94 ± 0.307
0.0ProTrp: 0.0 ± 0.0
3.529ProTyr: 3.529 ± 0.597
0.0ProXaa: 0.0 ± 0.0
Gln
2.117GlnAla: 2.117 ± 0.549
0.706GlnCys: 0.706 ± 0.452
2.117GlnAsp: 2.117 ± 0.403
0.706GlnGlu: 0.706 ± 0.452
2.823GlnPhe: 2.823 ± 0.097
0.706GlnGly: 0.706 ± 0.452
0.0GlnHis: 0.0 ± 0.0
2.117GlnIle: 2.117 ± 0.403
0.706GlnLys: 0.706 ± 0.452
1.411GlnLeu: 1.411 ± 0.048
0.0GlnMet: 0.0 ± 0.0
1.411GlnAsn: 1.411 ± 1.0
2.823GlnPro: 2.823 ± 1.807
0.0GlnGln: 0.0 ± 0.0
2.823GlnArg: 2.823 ± 0.097
3.529GlnSer: 3.529 ± 0.355
1.411GlnThr: 1.411 ± 1.0
1.411GlnVal: 1.411 ± 0.904
0.0GlnTrp: 0.0 ± 0.0
1.411GlnTyr: 1.411 ± 0.904
0.0GlnXaa: 0.0 ± 0.0
Arg
3.529ArgAla: 3.529 ± 1.549
0.0ArgCys: 0.0 ± 0.0
2.823ArgAsp: 2.823 ± 0.855
0.706ArgGlu: 0.706 ± 0.5
1.411ArgPhe: 1.411 ± 0.048
0.706ArgGly: 0.706 ± 0.452
2.823ArgHis: 2.823 ± 1.049
4.234ArgIle: 4.234 ± 0.807
2.823ArgLys: 2.823 ± 0.855
4.94ArgLeu: 4.94 ± 0.307
1.411ArgMet: 1.411 ± 0.904
3.529ArgAsn: 3.529 ± 0.355
6.351ArgPro: 6.351 ± 0.694
0.706ArgGln: 0.706 ± 0.452
3.529ArgArg: 3.529 ± 0.355
3.529ArgSer: 3.529 ± 0.597
6.351ArgThr: 6.351 ± 0.258
3.529ArgVal: 3.529 ± 0.597
0.706ArgTrp: 0.706 ± 0.5
2.823ArgTyr: 2.823 ± 0.855
0.0ArgXaa: 0.0 ± 0.0
Ser
6.351SerAla: 6.351 ± 2.598
0.706SerCys: 0.706 ± 0.452
4.94SerAsp: 4.94 ± 0.645
3.529SerGlu: 3.529 ± 2.259
5.646SerPhe: 5.646 ± 0.193
1.411SerGly: 1.411 ± 0.048
1.411SerHis: 1.411 ± 1.0
3.529SerIle: 3.529 ± 0.597
5.646SerLys: 5.646 ± 1.711
4.94SerLeu: 4.94 ± 1.597
0.0SerMet: 0.0 ± 0.0
2.823SerAsn: 2.823 ± 0.097
3.529SerPro: 3.529 ± 0.355
2.117SerGln: 2.117 ± 0.549
4.234SerArg: 4.234 ± 0.807
4.94SerSer: 4.94 ± 2.549
3.529SerThr: 3.529 ± 0.597
1.411SerVal: 1.411 ± 0.048
0.706SerTrp: 0.706 ± 0.5
3.529SerTyr: 3.529 ± 1.307
0.0SerXaa: 0.0 ± 0.0
Thr
6.351ThrAla: 6.351 ± 1.646
0.706ThrCys: 0.706 ± 0.5
4.94ThrAsp: 4.94 ± 0.645
1.411ThrGlu: 1.411 ± 1.0
4.234ThrPhe: 4.234 ± 0.807
3.529ThrGly: 3.529 ± 0.355
1.411ThrHis: 1.411 ± 0.904
3.529ThrIle: 3.529 ± 1.549
5.646ThrLys: 5.646 ± 2.098
9.174ThrLeu: 9.174 ± 0.79
1.411ThrMet: 1.411 ± 0.904
2.117ThrAsn: 2.117 ± 0.549
5.646ThrPro: 5.646 ± 1.146
2.117ThrGln: 2.117 ± 0.403
4.94ThrArg: 4.94 ± 0.645
4.234ThrSer: 4.234 ± 1.097
3.529ThrThr: 3.529 ± 1.549
6.351ThrVal: 6.351 ± 0.694
1.411ThrTrp: 1.411 ± 0.048
5.646ThrTyr: 5.646 ± 0.759
0.0ThrXaa: 0.0 ± 0.0
Val
3.529ValAla: 3.529 ± 0.597
0.0ValCys: 0.0 ± 0.0
2.823ValAsp: 2.823 ± 0.097
2.117ValGlu: 2.117 ± 0.403
2.117ValPhe: 2.117 ± 1.501
0.0ValGly: 0.0 ± 0.0
2.823ValHis: 2.823 ± 0.097
5.646ValIle: 5.646 ± 0.759
1.411ValLys: 1.411 ± 0.048
7.763ValLeu: 7.763 ± 0.742
0.0ValMet: 0.0 ± 0.359
4.234ValAsn: 4.234 ± 1.097
7.057ValPro: 7.057 ± 0.242
1.411ValGln: 1.411 ± 0.904
2.117ValArg: 2.117 ± 0.403
0.0ValSer: 0.0 ± 0.0
2.823ValThr: 2.823 ± 0.097
2.117ValVal: 2.117 ± 0.403
0.706ValTrp: 0.706 ± 0.5
3.529ValTyr: 3.529 ± 0.355
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.706TrpAsn: 0.706 ± 0.452
0.706TrpPro: 0.706 ± 0.5
0.0TrpGln: 0.0 ± 0.0
1.411TrpArg: 1.411 ± 1.0
2.117TrpSer: 2.117 ± 0.549
0.0TrpThr: 0.0 ± 0.0
1.411TrpVal: 1.411 ± 1.0
0.0TrpTrp: 0.0 ± 0.0
0.706TrpTyr: 0.706 ± 0.452
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.763TyrAla: 7.763 ± 2.114
1.411TyrCys: 1.411 ± 0.048
4.234TyrAsp: 4.234 ± 0.807
4.94TyrGlu: 4.94 ± 1.259
2.823TyrPhe: 2.823 ± 0.855
2.117TyrGly: 2.117 ± 0.403
2.117TyrHis: 2.117 ± 1.355
2.117TyrIle: 2.117 ± 0.403
1.411TyrLys: 1.411 ± 0.048
3.529TyrLeu: 3.529 ± 1.307
2.117TyrMet: 2.117 ± 1.501
4.94TyrAsn: 4.94 ± 1.259
5.646TyrPro: 5.646 ± 1.711
3.529TyrGln: 3.529 ± 1.307
3.529TyrArg: 3.529 ± 0.355
5.646TyrSer: 5.646 ± 1.711
4.234TyrThr: 4.234 ± 2.049
1.411TyrVal: 1.411 ± 1.0
0.706TyrTrp: 0.706 ± 0.5
2.823TyrTyr: 2.823 ± 0.097
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1418 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski