Amino acid dipepetide frequency for Roseivivax sediminis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.889AlaAla: 18.889 ± 0.219	1.122AlaCys: 1.122 ± 0.028	7.093AlaAsp: 7.093 ± 0.083	9.552AlaGlu: 9.552 ± 0.107	4.403AlaPhe: 4.403 ± 0.065	11.726AlaGly: 11.726 ± 0.145	2.449AlaHis: 2.449 ± 0.045	5.624AlaIle: 5.624 ± 0.068	2.926AlaLys: 2.926 ± 0.057	14.612AlaLeu: 14.612 ± 0.134	3.825AlaMet: 3.825 ± 0.063	2.28AlaAsn: 2.28 ± 0.043	6.798AlaPro: 6.798 ± 0.086	4.187AlaGln: 4.187 ± 0.057	10.316AlaArg: 10.316 ± 0.096	5.606AlaSer: 5.606 ± 0.076	6.167AlaThr: 6.167 ± 0.072	8.764AlaVal: 8.764 ± 0.083	1.65AlaTrp: 1.65 ± 0.04	2.442AlaTyr: 2.442 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.114CysAla: 1.114 ± 0.03	0.11CysCys: 0.11 ± 0.01	0.598CysAsp: 0.598 ± 0.022	0.431CysGlu: 0.431 ± 0.021	0.299CysPhe: 0.299 ± 0.014	0.99CysGly: 0.99 ± 0.034	0.288CysHis: 0.288 ± 0.017	0.353CysIle: 0.353 ± 0.017	0.147CysLys: 0.147 ± 0.01	0.869CysLeu: 0.869 ± 0.027	0.163CysMet: 0.163 ± 0.013	0.187CysAsn: 0.187 ± 0.012	0.483CysPro: 0.483 ± 0.02	0.221CysGln: 0.221 ± 0.014	0.633CysArg: 0.633 ± 0.021	0.413CysSer: 0.413 ± 0.018	0.462CysThr: 0.462 ± 0.018	0.61CysVal: 0.61 ± 0.022	0.117CysTrp: 0.117 ± 0.01	0.184CysTyr: 0.184 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.862AspAla: 7.862 ± 0.09	0.459AspCys: 0.459 ± 0.021	3.783AspAsp: 3.783 ± 0.101	3.619AspGlu: 3.619 ± 0.061	2.298AspPhe: 2.298 ± 0.043	6.203AspGly: 6.203 ± 0.112	1.401AspHis: 1.401 ± 0.033	2.982AspIle: 2.982 ± 0.049	1.335AspLys: 1.335 ± 0.033	6.513AspLeu: 6.513 ± 0.079	1.59AspMet: 1.59 ± 0.039	1.237AspAsn: 1.237 ± 0.041	3.989AspPro: 3.989 ± 0.067	1.464AspGln: 1.464 ± 0.036	5.003AspArg: 5.003 ± 0.064	2.249AspSer: 2.249 ± 0.048	3.369AspThr: 3.369 ± 0.063	4.406AspVal: 4.406 ± 0.065	1.245AspTrp: 1.245 ± 0.032	1.567AspTyr: 1.567 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	9.63GluAla: 9.63 ± 0.107	0.376GluCys: 0.376 ± 0.02	3.883GluAsp: 3.883 ± 0.061	4.244GluGlu: 4.244 ± 0.06	1.678GluPhe: 1.678 ± 0.037	5.409GluGly: 5.409 ± 0.07	1.133GluHis: 1.133 ± 0.03	3.691GluIle: 3.691 ± 0.055	1.716GluLys: 1.716 ± 0.037	5.129GluLeu: 5.129 ± 0.063	1.903GluMet: 1.903 ± 0.04	1.594GluAsn: 1.594 ± 0.039	2.828GluPro: 2.828 ± 0.052	1.669GluGln: 1.669 ± 0.04	5.049GluArg: 5.049 ± 0.069	2.457GluSer: 2.457 ± 0.046	4.342GluThr: 4.342 ± 0.062	4.729GluVal: 4.729 ± 0.06	0.719GluTrp: 0.719 ± 0.024	1.012GluTyr: 1.012 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.498PheAla: 4.498 ± 0.067	0.404PheCys: 0.404 ± 0.018	2.88PheAsp: 2.88 ± 0.043	2.332PheGlu: 2.332 ± 0.049	1.319PhePhe: 1.319 ± 0.036	3.622PheGly: 3.622 ± 0.06	0.733PheHis: 0.733 ± 0.029	1.378PheIle: 1.378 ± 0.039	0.695PheLys: 0.695 ± 0.023	3.302PheLeu: 3.302 ± 0.063	0.761PheMet: 0.761 ± 0.021	0.867PheAsn: 0.867 ± 0.024	1.544PhePro: 1.544 ± 0.034	0.891PheGln: 0.891 ± 0.025	2.3PheArg: 2.3 ± 0.038	1.833PheSer: 1.833 ± 0.034	1.951PheThr: 1.951 ± 0.04	2.746PheVal: 2.746 ± 0.045	0.548PheTrp: 0.548 ± 0.021	0.839PheTyr: 0.839 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	11.322GlyAla: 11.322 ± 0.141	0.862GlyCys: 0.862 ± 0.028	5.282GlyAsp: 5.282 ± 0.104	5.24GlyGlu: 5.24 ± 0.066	3.463GlyPhe: 3.463 ± 0.049	8.455GlyGly: 8.455 ± 0.159	1.99GlyHis: 1.99 ± 0.042	4.417GlyIle: 4.417 ± 0.065	2.499GlyLys: 2.499 ± 0.053	9.34GlyLeu: 9.34 ± 0.092	2.51GlyMet: 2.51 ± 0.046	2.053GlyAsn: 2.053 ± 0.053	4.106GlyPro: 4.106 ± 0.061	2.9GlyGln: 2.9 ± 0.049	6.812GlyArg: 6.812 ± 0.074	4.364GlySer: 4.364 ± 0.066	5.331GlyThr: 5.331 ± 0.101	6.34GlyVal: 6.34 ± 0.066	1.523GlyTrp: 1.523 ± 0.037	2.282GlyTyr: 2.282 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.529HisAla: 2.529 ± 0.042	0.212HisCys: 0.212 ± 0.012	1.405HisAsp: 1.405 ± 0.028	1.145HisGlu: 1.145 ± 0.033	0.764HisPhe: 0.764 ± 0.022	2.055HisGly: 2.055 ± 0.04	0.546HisHis: 0.546 ± 0.021	0.845HisIle: 0.845 ± 0.025	0.41HisLys: 0.41 ± 0.019	2.079HisLeu: 2.079 ± 0.046	0.522HisMet: 0.522 ± 0.02	0.418HisAsn: 0.418 ± 0.017	1.367HisPro: 1.367 ± 0.033	0.502HisGln: 0.502 ± 0.017	1.487HisArg: 1.487 ± 0.035	0.858HisSer: 0.858 ± 0.027	0.774HisThr: 0.774 ± 0.026	1.674HisVal: 1.674 ± 0.039	0.325HisTrp: 0.325 ± 0.013	0.528HisTyr: 0.528 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.801IleAla: 6.801 ± 0.081	0.545IleCys: 0.545 ± 0.02	3.458IleAsp: 3.458 ± 0.061	3.425IleGlu: 3.425 ± 0.054	1.616IlePhe: 1.616 ± 0.037	4.677IleGly: 4.677 ± 0.067	0.827IleHis: 0.827 ± 0.023	1.586IleIle: 1.586 ± 0.038	0.966IleLys: 0.966 ± 0.03	4.499IleLeu: 4.499 ± 0.063	0.882IleMet: 0.882 ± 0.028	1.047IleAsn: 1.047 ± 0.037	2.105IlePro: 2.105 ± 0.041	0.963IleGln: 0.963 ± 0.028	3.25IleArg: 3.25 ± 0.053	2.421IleSer: 2.421 ± 0.04	2.402IleThr: 2.402 ± 0.042	3.956IleVal: 3.956 ± 0.065	0.614IleTrp: 0.614 ± 0.023	1.01IleTyr: 1.01 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	3.015LysAla: 3.015 ± 0.053	0.149LysCys: 0.149 ± 0.01	1.403LysAsp: 1.403 ± 0.038	1.298LysGlu: 1.298 ± 0.037	0.64LysPhe: 0.64 ± 0.023	2.089LysGly: 2.089 ± 0.051	0.489LysHis: 0.489 ± 0.017	1.253LysIle: 1.253 ± 0.035	0.896LysLys: 0.896 ± 0.035	2.351LysLeu: 2.351 ± 0.049	0.655LysMet: 0.655 ± 0.023	0.574LysAsn: 0.574 ± 0.02	1.408LysPro: 1.408 ± 0.034	0.635LysGln: 0.635 ± 0.022	1.951LysArg: 1.951 ± 0.046	1.389LysSer: 1.389 ± 0.037	1.614LysThr: 1.614 ± 0.038	1.834LysVal: 1.834 ± 0.04	0.312LysTrp: 0.312 ± 0.014	0.491LysTyr: 0.491 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.438LeuAla: 13.438 ± 0.126	0.996LeuCys: 0.996 ± 0.028	6.356LeuAsp: 6.356 ± 0.081	5.514LeuGlu: 5.514 ± 0.067	3.436LeuPhe: 3.436 ± 0.058	8.758LeuGly: 8.758 ± 0.099	1.911LeuHis: 1.911 ± 0.043	4.608LeuIle: 4.608 ± 0.07	2.534LeuLys: 2.534 ± 0.043	8.755LeuLeu: 8.755 ± 0.122	2.463LeuMet: 2.463 ± 0.043	2.224LeuAsn: 2.224 ± 0.043	5.605LeuPro: 5.605 ± 0.07	2.447LeuGln: 2.447 ± 0.046	7.574LeuArg: 7.574 ± 0.087	6.759LeuSer: 6.759 ± 0.085	5.86LeuThr: 5.86 ± 0.064	7.134LeuVal: 7.134 ± 0.079	1.362LeuTrp: 1.362 ± 0.034	1.926LeuTyr: 1.926 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.208MetAla: 3.208 ± 0.056	0.174MetCys: 0.174 ± 0.012	1.302MetAsp: 1.302 ± 0.035	1.278MetGlu: 1.278 ± 0.03	0.752MetPhe: 0.752 ± 0.028	2.062MetGly: 2.062 ± 0.039	0.496MetHis: 0.496 ± 0.018	1.353MetIle: 1.353 ± 0.033	0.868MetLys: 0.868 ± 0.026	2.492MetLeu: 2.492 ± 0.044	0.694MetMet: 0.694 ± 0.03	0.738MetAsn: 0.738 ± 0.028	1.503MetPro: 1.503 ± 0.038	0.918MetGln: 0.918 ± 0.022	1.994MetArg: 1.994 ± 0.041	1.705MetSer: 1.705 ± 0.041	2.071MetThr: 2.071 ± 0.039	1.662MetVal: 1.662 ± 0.034	0.239MetTrp: 0.239 ± 0.013	0.303MetTyr: 0.303 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.863AsnAla: 2.863 ± 0.047	0.232AsnCys: 0.232 ± 0.014	1.367AsnAsp: 1.367 ± 0.044	1.084AsnGlu: 1.084 ± 0.034	0.814AsnPhe: 0.814 ± 0.025	2.106AsnGly: 2.106 ± 0.043	0.424AsnHis: 0.424 ± 0.02	1.077AsnIle: 1.077 ± 0.028	0.442AsnLys: 0.442 ± 0.02	2.182AsnLeu: 2.182 ± 0.043	0.558AsnMet: 0.558 ± 0.019	0.538AsnAsn: 0.538 ± 0.022	1.578AsnPro: 1.578 ± 0.04	0.576AsnGln: 0.576 ± 0.02	1.615AsnArg: 1.615 ± 0.036	0.957AsnSer: 0.957 ± 0.027	1.112AsnThr: 1.112 ± 0.032	1.801AsnVal: 1.801 ± 0.033	0.361AsnTrp: 0.361 ± 0.017	0.555AsnTyr: 0.555 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.429ProAla: 6.429 ± 0.08	0.373ProCys: 0.373 ± 0.019	4.207ProAsp: 4.207 ± 0.066	4.808ProGlu: 4.808 ± 0.07	1.955ProPhe: 1.955 ± 0.038	5.132ProGly: 5.132 ± 0.063	1.101ProHis: 1.101 ± 0.033	2.011ProIle: 2.011 ± 0.042	1.335ProLys: 1.335 ± 0.038	4.701ProLeu: 4.701 ± 0.071	1.236ProMet: 1.236 ± 0.029	1.132ProAsn: 1.132 ± 0.031	2.601ProPro: 2.601 ± 0.058	1.598ProGln: 1.598 ± 0.037	3.264ProArg: 3.264 ± 0.058	2.491ProSer: 2.491 ± 0.045	2.33ProThr: 2.33 ± 0.039	4.367ProVal: 4.367 ± 0.06	0.708ProTrp: 0.708 ± 0.024	1.13ProTyr: 1.13 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.615GlnAla: 3.615 ± 0.049	0.185GlnCys: 0.185 ± 0.013	1.642GlnAsp: 1.642 ± 0.037	1.625GlnGlu: 1.625 ± 0.048	0.863GlnPhe: 0.863 ± 0.028	2.383GlnGly: 2.383 ± 0.044	0.555GlnHis: 0.555 ± 0.021	1.664GlnIle: 1.664 ± 0.037	0.836GlnLys: 0.836 ± 0.027	2.405GlnLeu: 2.405 ± 0.045	0.862GlnMet: 0.862 ± 0.028	0.741GlnAsn: 0.741 ± 0.025	1.475GlnPro: 1.475 ± 0.035	0.897GlnGln: 0.897 ± 0.035	2.101GlnArg: 2.101 ± 0.042	1.675GlnSer: 1.675 ± 0.04	1.613GlnThr: 1.613 ± 0.042	2.081GlnVal: 2.081 ± 0.044	0.318GlnTrp: 0.318 ± 0.016	0.519GlnTyr: 0.519 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	9.548ArgAla: 9.548 ± 0.103	0.531ArgCys: 0.531 ± 0.02	4.634ArgAsp: 4.634 ± 0.066	4.449ArgGlu: 4.449 ± 0.069	2.875ArgPhe: 2.875 ± 0.047	5.432ArgGly: 5.432 ± 0.069	1.739ArgHis: 1.739 ± 0.037	4.064ArgIle: 4.064 ± 0.053	1.936ArgLys: 1.936 ± 0.048	8.107ArgLeu: 8.107 ± 0.086	2.058ArgMet: 2.058 ± 0.043	1.655ArgAsn: 1.655 ± 0.035	3.899ArgPro: 3.899 ± 0.073	2.351ArgGln: 2.351 ± 0.05	6.209ArgArg: 6.209 ± 0.088	3.517ArgSer: 3.517 ± 0.054	3.533ArgThr: 3.533 ± 0.052	5.288ArgVal: 5.288 ± 0.072	1.01ArgTrp: 1.01 ± 0.03	1.649ArgTyr: 1.649 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.002SerAla: 6.002 ± 0.069	0.441SerCys: 0.441 ± 0.018	3.38SerAsp: 3.38 ± 0.053	3.157SerGlu: 3.157 ± 0.054	2.011SerPhe: 2.011 ± 0.038	5.627SerGly: 5.627 ± 0.09	1.016SerHis: 1.016 ± 0.03	2.195SerIle: 2.195 ± 0.041	1.163SerLys: 1.163 ± 0.028	4.651SerLeu: 4.651 ± 0.063	1.193SerMet: 1.193 ± 0.031	1.161SerAsn: 1.161 ± 0.028	2.426SerPro: 2.426 ± 0.038	1.364SerGln: 1.364 ± 0.026	3.429SerArg: 3.429 ± 0.055	2.396SerSer: 2.396 ± 0.05	2.312SerThr: 2.312 ± 0.042	3.902SerVal: 3.902 ± 0.057	0.644SerTrp: 0.644 ± 0.022	1.272SerTyr: 1.272 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.304ThrAla: 6.304 ± 0.069	0.49ThrCys: 0.49 ± 0.018	3.378ThrAsp: 3.378 ± 0.062	3.389ThrGlu: 3.389 ± 0.057	2.058ThrPhe: 2.058 ± 0.041	5.733ThrGly: 5.733 ± 0.088	1.068ThrHis: 1.068 ± 0.027	2.571ThrIle: 2.571 ± 0.05	1.119ThrLys: 1.119 ± 0.03	6.4ThrLeu: 6.4 ± 0.083	1.24ThrMet: 1.24 ± 0.028	1.105ThrAsn: 1.105 ± 0.033	3.383ThrPro: 3.383 ± 0.05	1.364ThrGln: 1.364 ± 0.033	3.832ThrArg: 3.832 ± 0.057	2.582ThrSer: 2.582 ± 0.049	2.685ThrThr: 2.685 ± 0.053	4.235ThrVal: 4.235 ± 0.067	0.748ThrTrp: 0.748 ± 0.025	1.155ThrTyr: 1.155 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	9.389ValAla: 9.389 ± 0.097	0.645ValCys: 0.645 ± 0.022	4.142ValAsp: 4.142 ± 0.062	4.618ValGlu: 4.618 ± 0.064	2.871ValPhe: 2.871 ± 0.041	5.529ValGly: 5.529 ± 0.064	1.426ValHis: 1.426 ± 0.036	3.847ValIle: 3.847 ± 0.061	1.797ValLys: 1.797 ± 0.042	7.478ValLeu: 7.478 ± 0.082	1.912ValMet: 1.912 ± 0.041	1.792ValAsn: 1.792 ± 0.034	4.042ValPro: 4.042 ± 0.054	1.93ValGln: 1.93 ± 0.035	4.747ValArg: 4.747 ± 0.069	4.271ValSer: 4.271 ± 0.067	4.999ValThr: 4.999 ± 0.077	5.759ValVal: 5.759 ± 0.076	1.014ValTrp: 1.014 ± 0.027	1.475ValTyr: 1.475 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.471TrpAla: 1.471 ± 0.034	0.142TrpCys: 0.142 ± 0.01	0.763TrpAsp: 0.763 ± 0.026	0.702TrpGlu: 0.702 ± 0.022	0.525TrpPhe: 0.525 ± 0.019	1.038TrpGly: 1.038 ± 0.031	0.366TrpHis: 0.366 ± 0.017	0.71TrpIle: 0.71 ± 0.022	0.385TrpLys: 0.385 ± 0.016	1.618TrpLeu: 1.618 ± 0.04	0.372TrpMet: 0.372 ± 0.018	0.395TrpAsn: 0.395 ± 0.017	0.741TrpPro: 0.741 ± 0.023	0.588TrpGln: 0.588 ± 0.022	1.26TrpArg: 1.26 ± 0.031	0.782TrpSer: 0.782 ± 0.025	0.83TrpThr: 0.83 ± 0.025	0.85TrpVal: 0.85 ± 0.03	0.244TrpTrp: 0.244 ± 0.014	0.27TrpTyr: 0.27 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.504TyrAla: 2.504 ± 0.047	0.223TyrCys: 0.223 ± 0.012	1.617TyrAsp: 1.617 ± 0.037	1.281TyrGlu: 1.281 ± 0.033	0.805TyrPhe: 0.805 ± 0.025	2.067TyrGly: 2.067 ± 0.043	0.485TyrHis: 0.485 ± 0.018	0.818TyrIle: 0.818 ± 0.025	0.441TyrLys: 0.441 ± 0.019	2.177TyrLeu: 2.177 ± 0.044	0.414TyrMet: 0.414 ± 0.019	0.502TyrAsn: 0.502 ± 0.022	1.028TyrPro: 1.028 ± 0.027	0.592TyrGln: 0.592 ± 0.02	1.659TyrArg: 1.659 ± 0.038	1.018TyrSer: 1.018 ± 0.027	1.083TyrThr: 1.083 ± 0.032	1.545TyrVal: 1.545 ± 0.041	0.35TyrTrp: 0.35 ± 0.02	0.566TyrTyr: 0.566 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4371 proteins (1359608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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