Amino acid dipepetide frequency for Arachidicoccus ginsenosidivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.022AlaAla: 7.022 ± 0.104	0.648AlaCys: 0.648 ± 0.023	4.303AlaAsp: 4.303 ± 0.056	3.598AlaGlu: 3.598 ± 0.06	3.515AlaPhe: 3.515 ± 0.055	5.847AlaGly: 5.847 ± 0.072	1.399AlaHis: 1.399 ± 0.033	5.352AlaIle: 5.352 ± 0.068	4.634AlaLys: 4.634 ± 0.069	7.238AlaLeu: 7.238 ± 0.086	1.782AlaMet: 1.782 ± 0.039	3.464AlaAsn: 3.464 ± 0.053	2.805AlaPro: 2.805 ± 0.048	2.831AlaGln: 2.831 ± 0.05	2.648AlaArg: 2.648 ± 0.048	4.997AlaSer: 4.997 ± 0.06	4.548AlaThr: 4.548 ± 0.063	4.681AlaVal: 4.681 ± 0.057	0.841AlaTrp: 0.841 ± 0.027	3.037AlaTyr: 3.037 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.517CysAla: 0.517 ± 0.019	0.159CysCys: 0.159 ± 0.011	0.381CysAsp: 0.381 ± 0.017	0.291CysGlu: 0.291 ± 0.016	0.496CysPhe: 0.496 ± 0.02	0.64CysGly: 0.64 ± 0.022	0.21CysHis: 0.21 ± 0.013	0.619CysIle: 0.619 ± 0.022	0.513CysLys: 0.513 ± 0.019	0.931CysLeu: 0.931 ± 0.027	0.225CysMet: 0.225 ± 0.014	0.417CysAsn: 0.417 ± 0.017	0.334CysPro: 0.334 ± 0.019	0.348CysGln: 0.348 ± 0.015	0.32CysArg: 0.32 ± 0.016	0.605CysSer: 0.605 ± 0.022	0.442CysThr: 0.442 ± 0.017	0.432CysVal: 0.432 ± 0.018	0.117CysTrp: 0.117 ± 0.009	0.342CysTyr: 0.342 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.792AspAla: 3.792 ± 0.054	0.421AspCys: 0.421 ± 0.018	2.312AspAsp: 2.312 ± 0.068	2.518AspGlu: 2.518 ± 0.063	3.137AspPhe: 3.137 ± 0.049	4.057AspGly: 4.057 ± 0.074	1.198AspHis: 1.198 ± 0.03	3.927AspIle: 3.927 ± 0.056	3.869AspLys: 3.869 ± 0.068	5.393AspLeu: 5.393 ± 0.062	1.126AspMet: 1.126 ± 0.029	2.914AspAsn: 2.914 ± 0.055	2.483AspPro: 2.483 ± 0.042	2.557AspGln: 2.557 ± 0.05	2.174AspArg: 2.174 ± 0.037	3.801AspSer: 3.801 ± 0.064	2.668AspThr: 2.668 ± 0.054	2.818AspVal: 2.818 ± 0.047	0.936AspTrp: 0.936 ± 0.029	2.885AspTyr: 2.885 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	4.087GluAla: 4.087 ± 0.067	0.261GluCys: 0.261 ± 0.014	2.671GluAsp: 2.671 ± 0.064	2.534GluGlu: 2.534 ± 0.062	1.898GluPhe: 1.898 ± 0.043	3.294GluGly: 3.294 ± 0.048	0.977GluHis: 0.977 ± 0.029	3.728GluIle: 3.728 ± 0.063	4.254GluLys: 4.254 ± 0.066	4.936GluLeu: 4.936 ± 0.068	1.29GluMet: 1.29 ± 0.028	3.189GluAsn: 3.189 ± 0.052	1.508GluPro: 1.508 ± 0.035	2.476GluGln: 2.476 ± 0.05	2.066GluArg: 2.066 ± 0.046	2.569GluSer: 2.569 ± 0.054	2.381GluThr: 2.381 ± 0.045	3.207GluVal: 3.207 ± 0.058	0.556GluTrp: 0.556 ± 0.017	1.528GluTyr: 1.528 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	2.937PheAla: 2.937 ± 0.045	0.461PheCys: 0.461 ± 0.021	2.856PheAsp: 2.856 ± 0.053	2.494PheGlu: 2.494 ± 0.045	2.057PhePhe: 2.057 ± 0.042	3.332PheGly: 3.332 ± 0.053	0.867PheHis: 0.867 ± 0.029	3.209PheIle: 3.209 ± 0.052	3.374PheLys: 3.374 ± 0.056	3.994PheLeu: 3.994 ± 0.065	1.214PheMet: 1.214 ± 0.032	2.865PheAsn: 2.865 ± 0.05	1.713PhePro: 1.713 ± 0.038	1.587PheGln: 1.587 ± 0.035	1.725PheArg: 1.725 ± 0.038	3.535PheSer: 3.535 ± 0.056	2.875PheThr: 2.875 ± 0.045	2.599PheVal: 2.599 ± 0.05	0.661PheTrp: 0.661 ± 0.026	2.132PheTyr: 2.132 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	5.137GlyAla: 5.137 ± 0.079	0.669GlyCys: 0.669 ± 0.023	3.651GlyAsp: 3.651 ± 0.056	2.906GlyGlu: 2.906 ± 0.049	3.475GlyPhe: 3.475 ± 0.063	5.164GlyGly: 5.164 ± 0.096	1.556GlyHis: 1.556 ± 0.038	5.073GlyIle: 5.073 ± 0.061	5.396GlyLys: 5.396 ± 0.074	6.608GlyLeu: 6.608 ± 0.074	1.698GlyMet: 1.698 ± 0.037	3.912GlyAsn: 3.912 ± 0.068	1.84GlyPro: 1.84 ± 0.037	3.091GlyGln: 3.091 ± 0.046	2.758GlyArg: 2.758 ± 0.048	4.812GlySer: 4.812 ± 0.072	4.029GlyThr: 4.029 ± 0.068	4.401GlyVal: 4.401 ± 0.062	1.255GlyTrp: 1.255 ± 0.032	3.419GlyTyr: 3.419 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.19HisAla: 1.19 ± 0.028	0.198HisCys: 0.198 ± 0.011	0.879HisAsp: 0.879 ± 0.027	0.914HisGlu: 0.914 ± 0.027	1.365HisPhe: 1.365 ± 0.035	1.241HisGly: 1.241 ± 0.03	0.586HisHis: 0.586 ± 0.024	1.522HisIle: 1.522 ± 0.032	1.282HisLys: 1.282 ± 0.034	2.196HisLeu: 2.196 ± 0.043	0.462HisMet: 0.462 ± 0.015	1.043HisAsn: 1.043 ± 0.024	1.263HisPro: 1.263 ± 0.028	0.972HisGln: 0.972 ± 0.028	0.821HisArg: 0.821 ± 0.026	1.207HisSer: 1.207 ± 0.031	1.07HisThr: 1.07 ± 0.031	0.947HisVal: 0.947 ± 0.026	0.329HisTrp: 0.329 ± 0.017	1.165HisTyr: 1.165 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.285IleAla: 5.285 ± 0.076	0.756IleCys: 0.756 ± 0.023	4.146IleAsp: 4.146 ± 0.05	3.78IleGlu: 3.78 ± 0.057	2.94IlePhe: 2.94 ± 0.058	4.711IleGly: 4.711 ± 0.069	1.517IleHis: 1.517 ± 0.033	4.797IleIle: 4.797 ± 0.072	4.925IleLys: 4.925 ± 0.057	6.223IleLeu: 6.223 ± 0.084	1.398IleMet: 1.398 ± 0.032	4.03IleAsn: 4.03 ± 0.06	2.816IlePro: 2.816 ± 0.045	2.956IleGln: 2.956 ± 0.05	3.157IleArg: 3.157 ± 0.048	4.912IleSer: 4.912 ± 0.061	4.355IleThr: 4.355 ± 0.057	3.678IleVal: 3.678 ± 0.055	0.836IleTrp: 0.836 ± 0.023	2.896IleTyr: 2.896 ± 0.052	0.0IleXaa: 0.0 ± 0.0
Lys	5.484LysAla: 5.484 ± 0.076	0.36LysCys: 0.36 ± 0.017	4.45LysAsp: 4.45 ± 0.068	4.352LysGlu: 4.352 ± 0.069	2.323LysPhe: 2.323 ± 0.044	4.85LysGly: 4.85 ± 0.067	1.252LysHis: 1.252 ± 0.037	4.801LysIle: 4.801 ± 0.071	5.349LysLys: 5.349 ± 0.08	5.757LysLeu: 5.757 ± 0.056	1.976LysMet: 1.976 ± 0.041	3.997LysAsn: 3.997 ± 0.055	2.453LysPro: 2.453 ± 0.045	2.906LysGln: 2.906 ± 0.047	2.824LysArg: 2.824 ± 0.056	4.277LysSer: 4.277 ± 0.052	4.091LysThr: 4.091 ± 0.06	4.221LysVal: 4.221 ± 0.058	0.991LysTrp: 0.991 ± 0.028	2.799LysTyr: 2.799 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	6.625LeuAla: 6.625 ± 0.074	0.867LeuCys: 0.867 ± 0.028	5.067LeuAsp: 5.067 ± 0.062	4.788LeuGlu: 4.788 ± 0.072	4.582LeuPhe: 4.582 ± 0.067	6.028LeuGly: 6.028 ± 0.068	2.027LeuHis: 2.027 ± 0.043	6.489LeuIle: 6.489 ± 0.083	7.003LeuLys: 7.003 ± 0.073	9.649LeuLeu: 9.649 ± 0.121	2.326LeuMet: 2.326 ± 0.042	5.215LeuAsn: 5.215 ± 0.07	4.38LeuPro: 4.38 ± 0.055	4.222LeuGln: 4.222 ± 0.062	3.746LeuArg: 3.746 ± 0.055	7.212LeuSer: 7.212 ± 0.085	5.414LeuThr: 5.414 ± 0.07	4.939LeuVal: 4.939 ± 0.064	1.083LeuTrp: 1.083 ± 0.028	3.662LeuTyr: 3.662 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.173MetAla: 2.173 ± 0.039	0.139MetCys: 0.139 ± 0.009	1.546MetAsp: 1.546 ± 0.036	1.463MetGlu: 1.463 ± 0.038	0.732MetPhe: 0.732 ± 0.024	1.674MetGly: 1.674 ± 0.041	0.59MetHis: 0.59 ± 0.022	1.467MetIle: 1.467 ± 0.034	1.66MetLys: 1.66 ± 0.032	2.071MetLeu: 2.071 ± 0.037	0.646MetMet: 0.646 ± 0.023	1.128MetAsn: 1.128 ± 0.028	1.079MetPro: 1.079 ± 0.029	1.284MetGln: 1.284 ± 0.032	1.029MetArg: 1.029 ± 0.029	1.343MetSer: 1.343 ± 0.029	1.26MetThr: 1.26 ± 0.03	1.51MetVal: 1.51 ± 0.033	0.215MetTrp: 0.215 ± 0.013	0.664MetTyr: 0.664 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.848AsnAla: 3.848 ± 0.058	0.474AsnCys: 0.474 ± 0.022	2.557AsnAsp: 2.557 ± 0.041	2.464AsnGlu: 2.464 ± 0.047	2.375AsnPhe: 2.375 ± 0.045	4.344AsnGly: 4.344 ± 0.066	1.057AsnHis: 1.057 ± 0.03	3.871AsnIle: 3.871 ± 0.063	3.937AsnLys: 3.937 ± 0.055	4.926AsnLeu: 4.926 ± 0.067	1.184AsnMet: 1.184 ± 0.027	3.37AsnAsn: 3.37 ± 0.071	2.715AsnPro: 2.715 ± 0.048	2.407AsnGln: 2.407 ± 0.046	2.204AsnArg: 2.204 ± 0.043	3.316AsnSer: 3.316 ± 0.063	3.324AsnThr: 3.324 ± 0.064	2.71AsnVal: 2.71 ± 0.05	0.866AsnTrp: 0.866 ± 0.025	2.614AsnTyr: 2.614 ± 0.054	0.0AsnXaa: 0.0 ± 0.0
Pro	3.402ProAla: 3.402 ± 0.053	0.243ProCys: 0.243 ± 0.013	2.796ProAsp: 2.796 ± 0.046	2.675ProGlu: 2.675 ± 0.05	1.982ProPhe: 1.982 ± 0.042	3.046ProGly: 3.046 ± 0.054	0.723ProHis: 0.723 ± 0.027	2.569ProIle: 2.569 ± 0.042	2.432ProLys: 2.432 ± 0.047	3.613ProLeu: 3.613 ± 0.056	0.887ProMet: 0.887 ± 0.026	1.931ProAsn: 1.931 ± 0.041	1.108ProPro: 1.108 ± 0.033	1.292ProGln: 1.292 ± 0.034	1.212ProArg: 1.212 ± 0.028	2.493ProSer: 2.493 ± 0.047	2.234ProThr: 2.234 ± 0.043	2.983ProVal: 2.983 ± 0.047	0.57ProTrp: 0.57 ± 0.021	1.761ProTyr: 1.761 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.2GlnAla: 3.2 ± 0.053	0.235GlnCys: 0.235 ± 0.015	2.066GlnAsp: 2.066 ± 0.042	1.825GlnGlu: 1.825 ± 0.04	1.853GlnPhe: 1.853 ± 0.035	2.511GlnGly: 2.511 ± 0.044	0.916GlnHis: 0.916 ± 0.026	3.142GlnIle: 3.142 ± 0.049	3.209GlnLys: 3.209 ± 0.056	4.471GlnLeu: 4.471 ± 0.066	1.159GlnMet: 1.159 ± 0.03	2.447GlnAsn: 2.447 ± 0.045	1.864GlnPro: 1.864 ± 0.04	2.62GlnGln: 2.62 ± 0.061	1.705GlnArg: 1.705 ± 0.04	2.561GlnSer: 2.561 ± 0.04	2.333GlnThr: 2.333 ± 0.044	2.712GlnVal: 2.712 ± 0.052	0.526GlnTrp: 0.526 ± 0.019	1.837GlnTyr: 1.837 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.586ArgAla: 2.586 ± 0.05	0.273ArgCys: 0.273 ± 0.013	1.908ArgAsp: 1.908 ± 0.044	1.954ArgGlu: 1.954 ± 0.039	2.126ArgPhe: 2.126 ± 0.041	2.16ArgGly: 2.16 ± 0.044	0.844ArgHis: 0.844 ± 0.026	2.991ArgIle: 2.991 ± 0.047	2.813ArgLys: 2.813 ± 0.044	4.181ArgLeu: 4.181 ± 0.062	1.08ArgMet: 1.08 ± 0.028	1.977ArgAsn: 1.977 ± 0.041	1.598ArgPro: 1.598 ± 0.039	1.914ArgGln: 1.914 ± 0.037	1.668ArgArg: 1.668 ± 0.041	2.451ArgSer: 2.451 ± 0.043	2.106ArgThr: 2.106 ± 0.043	2.123ArgVal: 2.123 ± 0.042	0.645ArgTrp: 0.645 ± 0.024	1.854ArgTyr: 1.854 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	4.961SerAla: 4.961 ± 0.069	0.691SerCys: 0.691 ± 0.023	3.52SerAsp: 3.52 ± 0.058	2.962SerGlu: 2.962 ± 0.043	3.47SerPhe: 3.47 ± 0.047	5.223SerGly: 5.223 ± 0.074	1.195SerHis: 1.195 ± 0.03	4.836SerIle: 4.836 ± 0.058	3.999SerLys: 3.999 ± 0.059	6.486SerLeu: 6.486 ± 0.075	1.498SerMet: 1.498 ± 0.036	3.262SerAsn: 3.262 ± 0.062	2.523SerPro: 2.523 ± 0.04	2.364SerGln: 2.364 ± 0.04	2.42SerArg: 2.42 ± 0.04	4.582SerSer: 4.582 ± 0.065	3.877SerThr: 3.877 ± 0.065	4.063SerVal: 4.063 ± 0.055	1.064SerTrp: 1.064 ± 0.034	2.923SerTyr: 2.923 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	4.801ThrAla: 4.801 ± 0.065	0.418ThrCys: 0.418 ± 0.02	3.421ThrAsp: 3.421 ± 0.058	2.619ThrGlu: 2.619 ± 0.049	2.465ThrPhe: 2.465 ± 0.04	5.025ThrGly: 5.025 ± 0.072	1.145ThrHis: 1.145 ± 0.029	4.043ThrIle: 4.043 ± 0.055	3.424ThrLys: 3.424 ± 0.047	5.524ThrLeu: 5.524 ± 0.067	1.01ThrMet: 1.01 ± 0.03	2.772ThrAsn: 2.772 ± 0.047	2.687ThrPro: 2.687 ± 0.05	2.177ThrGln: 2.177 ± 0.044	2.065ThrArg: 2.065 ± 0.037	3.598ThrSer: 3.598 ± 0.061	3.706ThrThr: 3.706 ± 0.069	3.57ThrVal: 3.57 ± 0.053	0.738ThrTrp: 0.738 ± 0.028	2.347ThrTyr: 2.347 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.46ValAla: 4.46 ± 0.066	0.512ValCys: 0.512 ± 0.019	3.25ValAsp: 3.25 ± 0.051	2.763ValGlu: 2.763 ± 0.05	2.761ValPhe: 2.761 ± 0.045	3.564ValGly: 3.564 ± 0.059	1.259ValHis: 1.259 ± 0.032	4.306ValIle: 4.306 ± 0.056	3.751ValLys: 3.751 ± 0.057	5.572ValLeu: 5.572 ± 0.073	1.368ValMet: 1.368 ± 0.032	3.099ValAsn: 3.099 ± 0.054	2.412ValPro: 2.412 ± 0.041	2.299ValGln: 2.299 ± 0.041	2.317ValArg: 2.317 ± 0.04	4.104ValSer: 4.104 ± 0.055	3.51ValThr: 3.51 ± 0.054	3.553ValVal: 3.553 ± 0.052	0.709ValTrp: 0.709 ± 0.029	2.438ValTyr: 2.438 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.896TrpAla: 0.896 ± 0.03	0.145TrpCys: 0.145 ± 0.009	0.818TrpAsp: 0.818 ± 0.026	0.671TrpGlu: 0.671 ± 0.022	0.587TrpPhe: 0.587 ± 0.024	0.945TrpGly: 0.945 ± 0.026	0.367TrpHis: 0.367 ± 0.016	0.85TrpIle: 0.85 ± 0.029	0.878TrpLys: 0.878 ± 0.03	1.42TrpLeu: 1.42 ± 0.034	0.43TrpMet: 0.43 ± 0.018	0.794TrpAsn: 0.794 ± 0.028	0.455TrpPro: 0.455 ± 0.023	0.812TrpGln: 0.812 ± 0.028	0.578TrpArg: 0.578 ± 0.02	0.794TrpSer: 0.794 ± 0.029	0.777TrpThr: 0.777 ± 0.022	0.768TrpVal: 0.768 ± 0.026	0.274TrpTrp: 0.274 ± 0.015	0.586TrpTyr: 0.586 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.786TyrAla: 2.786 ± 0.048	0.407TyrCys: 0.407 ± 0.017	2.386TyrAsp: 2.386 ± 0.055	1.837TyrGlu: 1.837 ± 0.037	2.347TyrPhe: 2.347 ± 0.045	3.197TyrGly: 3.197 ± 0.053	0.967TyrHis: 0.967 ± 0.025	2.521TyrIle: 2.521 ± 0.041	2.811TyrLys: 2.811 ± 0.046	4.134TyrLeu: 4.134 ± 0.06	0.913TyrMet: 0.913 ± 0.028	2.735TyrAsn: 2.735 ± 0.053	1.918TyrPro: 1.918 ± 0.037	2.079TyrGln: 2.079 ± 0.041	1.817TyrArg: 1.817 ± 0.041	2.752TyrSer: 2.752 ± 0.053	2.553TyrThr: 2.553 ± 0.042	2.091TyrVal: 2.091 ± 0.042	0.634TyrTrp: 0.634 ± 0.024	2.288TyrTyr: 2.288 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4066 proteins (1369608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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