Amino acid dipepetide frequency for fungal sp. No.14919

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.063AlaAla: 9.063 ± 0.053
1.083AlaCys: 1.083 ± 0.014
4.425AlaAsp: 4.425 ± 0.031
5.034AlaGlu: 5.034 ± 0.035
3.186AlaPhe: 3.186 ± 0.027
5.826AlaGly: 5.826 ± 0.038
1.828AlaHis: 1.828 ± 0.019
4.437AlaIle: 4.437 ± 0.029
3.944AlaLys: 3.944 ± 0.03
7.903AlaLeu: 7.903 ± 0.041
1.84AlaMet: 1.84 ± 0.015
3.005AlaAsn: 3.005 ± 0.025
4.663AlaPro: 4.663 ± 0.035
3.329AlaGln: 3.329 ± 0.024
5.095AlaArg: 5.095 ± 0.035
7.271AlaSer: 7.271 ± 0.038
5.533AlaThr: 5.533 ± 0.035
5.556AlaVal: 5.556 ± 0.036
1.192AlaTrp: 1.192 ± 0.013
2.25AlaTyr: 2.25 ± 0.018
0.0AlaXaa: 0.0 ± 0.0
Cys
0.937CysAla: 0.937 ± 0.014
0.248CysCys: 0.248 ± 0.008
0.696CysAsp: 0.696 ± 0.012
0.622CysGlu: 0.622 ± 0.011
0.524CysPhe: 0.524 ± 0.009
0.945CysGly: 0.945 ± 0.015
0.337CysHis: 0.337 ± 0.007
0.703CysIle: 0.703 ± 0.011
0.482CysLys: 0.482 ± 0.009
1.237CysLeu: 1.237 ± 0.015
0.249CysMet: 0.249 ± 0.006
0.434CysAsn: 0.434 ± 0.008
0.659CysPro: 0.659 ± 0.012
0.437CysGln: 0.437 ± 0.008
0.801CysArg: 0.801 ± 0.012
0.904CysSer: 0.904 ± 0.014
0.689CysThr: 0.689 ± 0.012
0.798CysVal: 0.798 ± 0.011
0.207CysTrp: 0.207 ± 0.006
0.361CysTyr: 0.361 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.856AspAla: 4.856 ± 0.029
0.658AspCys: 0.658 ± 0.011
4.368AspAsp: 4.368 ± 0.043
4.449AspGlu: 4.449 ± 0.032
2.255AspPhe: 2.255 ± 0.02
4.306AspGly: 4.306 ± 0.025
1.243AspHis: 1.243 ± 0.014
3.186AspIle: 3.186 ± 0.027
2.31AspLys: 2.31 ± 0.022
5.066AspLeu: 5.066 ± 0.031
1.231AspMet: 1.231 ± 0.013
1.984AspAsn: 1.984 ± 0.021
3.348AspPro: 3.348 ± 0.026
1.838AspGln: 1.838 ± 0.02
3.082AspArg: 3.082 ± 0.026
4.165AspSer: 4.165 ± 0.027
3.122AspThr: 3.122 ± 0.023
3.798AspVal: 3.798 ± 0.024
0.931AspTrp: 0.931 ± 0.011
1.685AspTyr: 1.685 ± 0.015
0.0AspXaa: 0.0 ± 0.0
Glu
5.404GluAla: 5.404 ± 0.039
0.648GluCys: 0.648 ± 0.01
4.042GluAsp: 4.042 ± 0.028
4.871GluGlu: 4.871 ± 0.044
1.977GluPhe: 1.977 ± 0.018
3.728GluGly: 3.728 ± 0.024
1.397GluHis: 1.397 ± 0.015
3.14GluIle: 3.14 ± 0.023
3.438GluLys: 3.438 ± 0.028
5.3GluLeu: 5.3 ± 0.032
1.355GluMet: 1.355 ± 0.016
2.335GluAsn: 2.335 ± 0.021
2.854GluPro: 2.854 ± 0.03
2.307GluGln: 2.307 ± 0.021
3.938GluArg: 3.938 ± 0.034
4.262GluSer: 4.262 ± 0.027
3.502GluThr: 3.502 ± 0.028
3.447GluVal: 3.447 ± 0.025
0.916GluTrp: 0.916 ± 0.014
1.733GluTyr: 1.733 ± 0.019
0.0GluXaa: 0.0 ± 0.0
Phe
3.052PheAla: 3.052 ± 0.027
0.522PheCys: 0.522 ± 0.009
2.321PheAsp: 2.321 ± 0.022
2.166PheGlu: 2.166 ± 0.02
1.576PhePhe: 1.576 ± 0.02
2.849PheGly: 2.849 ± 0.025
0.903PheHis: 0.903 ± 0.012
1.846PheIle: 1.846 ± 0.021
1.47PheLys: 1.47 ± 0.015
3.442PheLeu: 3.442 ± 0.03
0.732PheMet: 0.732 ± 0.011
1.438PheAsn: 1.438 ± 0.016
1.971PhePro: 1.971 ± 0.016
1.385PheGln: 1.385 ± 0.015
2.059PheArg: 2.059 ± 0.019
2.956PheSer: 2.956 ± 0.022
2.186PheThr: 2.186 ± 0.019
2.41PheVal: 2.41 ± 0.018
0.651PheTrp: 0.651 ± 0.011
1.114PheTyr: 1.114 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.623GlyAla: 5.623 ± 0.036
0.866GlyCys: 0.866 ± 0.014
3.895GlyAsp: 3.895 ± 0.027
3.668GlyGlu: 3.668 ± 0.024
2.81GlyPhe: 2.81 ± 0.02
5.848GlyGly: 5.848 ± 0.05
1.763GlyHis: 1.763 ± 0.018
3.61GlyIle: 3.61 ± 0.03
3.279GlyLys: 3.279 ± 0.027
6.245GlyLeu: 6.245 ± 0.031
1.422GlyMet: 1.422 ± 0.015
2.682GlyAsn: 2.682 ± 0.019
3.475GlyPro: 3.475 ± 0.029
2.485GlyGln: 2.485 ± 0.022
4.27GlyArg: 4.27 ± 0.028
5.809GlySer: 5.809 ± 0.034
4.094GlyThr: 4.094 ± 0.029
4.528GlyVal: 4.528 ± 0.029
1.19GlyTrp: 1.19 ± 0.015
2.176GlyTyr: 2.176 ± 0.02
0.0GlyXaa: 0.0 ± 0.0
His
1.816HisAla: 1.816 ± 0.018
0.345HisCys: 0.345 ± 0.008
1.381HisAsp: 1.381 ± 0.014
1.388HisGlu: 1.388 ± 0.017
0.909HisPhe: 0.909 ± 0.012
1.784HisGly: 1.784 ± 0.017
0.852HisHis: 0.852 ± 0.014
1.265HisIle: 1.265 ± 0.016
0.895HisLys: 0.895 ± 0.012
2.22HisLeu: 2.22 ± 0.019
0.497HisMet: 0.497 ± 0.01
0.863HisAsn: 0.863 ± 0.011
1.606HisPro: 1.606 ± 0.018
0.989HisGln: 0.989 ± 0.014
1.55HisArg: 1.55 ± 0.019
1.831HisSer: 1.831 ± 0.018
1.295HisThr: 1.295 ± 0.015
1.449HisVal: 1.449 ± 0.015
0.355HisTrp: 0.355 ± 0.008
0.723HisTyr: 0.723 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.312IleAla: 4.312 ± 0.03
0.755IleCys: 0.755 ± 0.012
3.032IleAsp: 3.032 ± 0.022
2.97IleGlu: 2.97 ± 0.021
1.985IlePhe: 1.985 ± 0.02
3.322IleGly: 3.322 ± 0.027
1.209IleHis: 1.209 ± 0.013
2.637IleIle: 2.637 ± 0.028
2.142IleLys: 2.142 ± 0.019
4.604IleLeu: 4.604 ± 0.039
0.998IleMet: 0.998 ± 0.012
1.859IleAsn: 1.859 ± 0.016
3.133IlePro: 3.133 ± 0.024
1.942IleGln: 1.942 ± 0.02
2.962IleArg: 2.962 ± 0.022
3.944IleSer: 3.944 ± 0.026
3.004IleThr: 3.004 ± 0.022
3.25IleVal: 3.25 ± 0.024
0.777IleTrp: 0.777 ± 0.012
1.433IleTyr: 1.433 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.107LysAla: 4.107 ± 0.032
0.479LysCys: 0.479 ± 0.01
2.585LysAsp: 2.585 ± 0.023
3.037LysGlu: 3.037 ± 0.029
1.434LysPhe: 1.434 ± 0.016
2.874LysGly: 2.874 ± 0.025
1.064LysHis: 1.064 ± 0.014
2.253LysIle: 2.253 ± 0.019
2.978LysLys: 2.978 ± 0.03
4.017LysLeu: 4.017 ± 0.027
0.921LysMet: 0.921 ± 0.012
1.646LysAsn: 1.646 ± 0.017
2.669LysPro: 2.669 ± 0.023
1.719LysGln: 1.719 ± 0.018
3.264LysArg: 3.264 ± 0.033
3.348LysSer: 3.348 ± 0.027
2.762LysThr: 2.762 ± 0.022
2.613LysVal: 2.613 ± 0.023
0.675LysTrp: 0.675 ± 0.011
1.351LysTyr: 1.351 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
8.03LeuAla: 8.03 ± 0.042
1.214LeuCys: 1.214 ± 0.014
5.294LeuAsp: 5.294 ± 0.031
5.565LeuGlu: 5.565 ± 0.041
3.321LeuPhe: 3.321 ± 0.028
6.206LeuGly: 6.206 ± 0.034
2.216LeuHis: 2.216 ± 0.02
3.985LeuIle: 3.985 ± 0.029
4.024LeuLys: 4.024 ± 0.03
8.439LeuLeu: 8.439 ± 0.056
1.666LeuMet: 1.666 ± 0.017
3.138LeuAsn: 3.138 ± 0.024
5.427LeuPro: 5.427 ± 0.034
3.699LeuGln: 3.699 ± 0.03
5.928LeuArg: 5.928 ± 0.032
7.3LeuSer: 7.3 ± 0.044
4.781LeuThr: 4.781 ± 0.03
5.61LeuVal: 5.61 ± 0.037
1.282LeuTrp: 1.282 ± 0.013
2.404LeuTyr: 2.404 ± 0.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.149MetAla: 2.149 ± 0.018
0.222MetCys: 0.222 ± 0.005
1.167MetAsp: 1.167 ± 0.014
1.178MetGlu: 1.178 ± 0.013
0.672MetPhe: 0.672 ± 0.011
1.352MetGly: 1.352 ± 0.016
0.453MetHis: 0.453 ± 0.009
0.94MetIle: 0.94 ± 0.011
0.95MetLys: 0.95 ± 0.015
1.731MetLeu: 1.731 ± 0.016
0.548MetMet: 0.548 ± 0.01
0.756MetAsn: 0.756 ± 0.012
1.222MetPro: 1.222 ± 0.012
0.783MetGln: 0.783 ± 0.013
1.282MetArg: 1.282 ± 0.014
1.737MetSer: 1.737 ± 0.016
1.232MetThr: 1.232 ± 0.015
1.22MetVal: 1.22 ± 0.015
0.247MetTrp: 0.247 ± 0.007
0.479MetTyr: 0.479 ± 0.009
0.0MetXaa: 0.0 ± 0.0
Asn
3.132AsnAla: 3.132 ± 0.026
0.467AsnCys: 0.467 ± 0.009
2.032AsnAsp: 2.032 ± 0.018
2.09AsnGlu: 2.09 ± 0.019
1.378AsnPhe: 1.378 ± 0.016
3.027AsnGly: 3.027 ± 0.029
0.861AsnHis: 0.861 ± 0.012
2.112AsnIle: 2.112 ± 0.019
1.503AsnLys: 1.503 ± 0.017
3.238AsnLeu: 3.238 ± 0.024
0.815AsnMet: 0.815 ± 0.012
1.551AsnAsn: 1.551 ± 0.019
2.494AsnPro: 2.494 ± 0.02
1.349AsnGln: 1.349 ± 0.017
2.01AsnArg: 2.01 ± 0.018
2.849AsnSer: 2.849 ± 0.022
2.333AsnThr: 2.333 ± 0.021
2.285AsnVal: 2.285 ± 0.021
0.578AsnTrp: 0.578 ± 0.008
1.092AsnTyr: 1.092 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
4.969ProAla: 4.969 ± 0.039
0.519ProCys: 0.519 ± 0.01
3.298ProAsp: 3.298 ± 0.024
3.817ProGlu: 3.817 ± 0.031
2.058ProPhe: 2.058 ± 0.019
4.048ProGly: 4.048 ± 0.033
1.338ProHis: 1.338 ± 0.016
2.701ProIle: 2.701 ± 0.022
2.537ProLys: 2.537 ± 0.023
4.758ProLeu: 4.758 ± 0.029
1.023ProMet: 1.023 ± 0.012
2.354ProAsn: 2.354 ± 0.021
5.009ProPro: 5.009 ± 0.061
2.411ProGln: 2.411 ± 0.026
3.565ProArg: 3.565 ± 0.029
5.94ProSer: 5.94 ± 0.043
4.146ProThr: 4.146 ± 0.036
3.474ProVal: 3.474 ± 0.028
0.812ProTrp: 0.812 ± 0.012
1.563ProTyr: 1.563 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
3.356GlnAla: 3.356 ± 0.025
0.459GlnCys: 0.459 ± 0.01
2.065GlnAsp: 2.065 ± 0.02
2.234GlnGlu: 2.234 ± 0.019
1.278GlnPhe: 1.278 ± 0.014
2.44GlnGly: 2.44 ± 0.021
1.057GlnHis: 1.057 ± 0.014
1.872GlnIle: 1.872 ± 0.018
1.834GlnLys: 1.834 ± 0.019
3.435GlnLeu: 3.435 ± 0.024
0.8GlnMet: 0.8 ± 0.014
1.513GlnAsn: 1.513 ± 0.018
2.527GlnPro: 2.527 ± 0.025
2.206GlnGln: 2.206 ± 0.046
2.561GlnArg: 2.561 ± 0.02
3.016GlnSer: 3.016 ± 0.027
2.266GlnThr: 2.266 ± 0.021
2.132GlnVal: 2.132 ± 0.019
0.601GlnTrp: 0.601 ± 0.01
1.177GlnTyr: 1.177 ± 0.014
0.0GlnXaa: 0.0 ± 0.0
Arg
4.896ArgAla: 4.896 ± 0.032
0.751ArgCys: 0.751 ± 0.013
3.65ArgAsp: 3.65 ± 0.03
3.914ArgGlu: 3.914 ± 0.033
2.187ArgPhe: 2.187 ± 0.02
3.965ArgGly: 3.965 ± 0.028
1.647ArgHis: 1.647 ± 0.019
3.039ArgIle: 3.039 ± 0.022
3.285ArgLys: 3.285 ± 0.028
5.678ArgLeu: 5.678 ± 0.032
1.296ArgMet: 1.296 ± 0.014
2.352ArgAsn: 2.352 ± 0.02
3.626ArgPro: 3.626 ± 0.029
2.572ArgGln: 2.572 ± 0.022
5.227ArgArg: 5.227 ± 0.042
4.714ArgSer: 4.714 ± 0.034
3.289ArgThr: 3.289 ± 0.026
3.539ArgVal: 3.539 ± 0.026
0.98ArgTrp: 0.98 ± 0.011
1.73ArgTyr: 1.73 ± 0.019
0.0ArgXaa: 0.0 ± 0.0
Ser
6.533SerAla: 6.533 ± 0.032
0.861SerCys: 0.861 ± 0.015
4.25SerAsp: 4.25 ± 0.03
4.097SerGlu: 4.097 ± 0.029
3.016SerPhe: 3.016 ± 0.026
5.654SerGly: 5.654 ± 0.038
2.003SerHis: 2.003 ± 0.019
4.123SerIle: 4.123 ± 0.029
3.512SerLys: 3.512 ± 0.025
7.213SerLeu: 7.213 ± 0.041
1.608SerMet: 1.608 ± 0.014
3.034SerAsn: 3.034 ± 0.024
5.425SerPro: 5.425 ± 0.039
3.292SerGln: 3.292 ± 0.024
5.168SerArg: 5.168 ± 0.036
8.562SerSer: 8.562 ± 0.064
5.611SerThr: 5.611 ± 0.046
4.573SerVal: 4.573 ± 0.029
1.193SerTrp: 1.193 ± 0.014
2.152SerTyr: 2.152 ± 0.017
0.0SerXaa: 0.0 ± 0.0
Thr
5.336ThrAla: 5.336 ± 0.035
0.762ThrCys: 0.762 ± 0.014
2.884ThrAsp: 2.884 ± 0.022
3.153ThrGlu: 3.153 ± 0.025
2.228ThrPhe: 2.228 ± 0.021
4.207ThrGly: 4.207 ± 0.03
1.318ThrHis: 1.318 ± 0.014
3.209ThrIle: 3.209 ± 0.027
2.598ThrLys: 2.598 ± 0.025
5.28ThrLeu: 5.28 ± 0.031
1.165ThrMet: 1.165 ± 0.015
2.225ThrAsn: 2.225 ± 0.02
4.402ThrPro: 4.402 ± 0.041
2.121ThrGln: 2.121 ± 0.016
3.33ThrArg: 3.33 ± 0.024
5.437ThrSer: 5.437 ± 0.046
4.495ThrThr: 4.495 ± 0.048
3.774ThrVal: 3.774 ± 0.029
0.896ThrTrp: 0.896 ± 0.012
1.695ThrTyr: 1.695 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.428ValAla: 5.428 ± 0.031
0.79ValCys: 0.79 ± 0.01
3.788ValAsp: 3.788 ± 0.029
3.844ValGlu: 3.844 ± 0.028
2.483ValPhe: 2.483 ± 0.021
4.151ValGly: 4.151 ± 0.032
1.375ValHis: 1.375 ± 0.013
3.012ValIle: 3.012 ± 0.025
2.75ValLys: 2.75 ± 0.023
5.659ValLeu: 5.659 ± 0.036
1.22ValMet: 1.22 ± 0.014
2.283ValAsn: 2.283 ± 0.021
3.585ValPro: 3.585 ± 0.03
2.262ValGln: 2.262 ± 0.02
3.533ValArg: 3.533 ± 0.024
4.681ValSer: 4.681 ± 0.029
3.613ValThr: 3.613 ± 0.025
4.428ValVal: 4.428 ± 0.032
0.874ValTrp: 0.874 ± 0.011
1.77ValTyr: 1.77 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.245TrpAla: 1.245 ± 0.015
0.204TrpCys: 0.204 ± 0.006
0.969TrpAsp: 0.969 ± 0.013
0.894TrpGlu: 0.894 ± 0.012
0.571TrpPhe: 0.571 ± 0.009
0.991TrpGly: 0.991 ± 0.014
0.369TrpHis: 0.369 ± 0.009
0.781TrpIle: 0.781 ± 0.011
0.769TrpLys: 0.769 ± 0.012
1.405TrpLeu: 1.405 ± 0.015
0.335TrpMet: 0.335 ± 0.007
0.649TrpAsn: 0.649 ± 0.009
0.667TrpPro: 0.667 ± 0.01
0.583TrpGln: 0.583 ± 0.01
1.014TrpArg: 1.014 ± 0.013
1.054TrpSer: 1.054 ± 0.013
0.921TrpThr: 0.921 ± 0.013
0.941TrpVal: 0.941 ± 0.012
0.277TrpTrp: 0.277 ± 0.007
0.467TrpTyr: 0.467 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.22TyrAla: 2.22 ± 0.02
0.418TyrCys: 0.418 ± 0.009
1.737TyrAsp: 1.737 ± 0.016
1.601TyrGlu: 1.601 ± 0.017
1.202TyrPhe: 1.202 ± 0.013
2.214TyrGly: 2.214 ± 0.021
0.779TyrHis: 0.779 ± 0.012
1.42TyrIle: 1.42 ± 0.019
1.092TyrLys: 1.092 ± 0.014
2.661TyrLeu: 2.661 ± 0.025
0.6TyrMet: 0.6 ± 0.01
1.098TyrAsn: 1.098 ± 0.013
1.577TyrPro: 1.577 ± 0.021
1.119TyrGln: 1.119 ± 0.014
1.699TyrArg: 1.699 ± 0.019
2.101TyrSer: 2.101 ± 0.021
1.643TyrThr: 1.643 ± 0.016
1.702TyrVal: 1.702 ± 0.018
0.474TyrTrp: 0.474 ± 0.008
0.989TyrTyr: 0.989 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 14332 proteins (6368111 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski