Amino acid dipepetide frequency for Capybara microvirus Cap3_SP_449

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.312AlaAla: 8.312 ± 4.447
1.918AlaCys: 1.918 ± 1.796
5.754AlaAsp: 5.754 ± 1.002
2.558AlaGlu: 2.558 ± 1.288
3.836AlaPhe: 3.836 ± 0.995
2.558AlaGly: 2.558 ± 1.501
0.639AlaHis: 0.639 ± 0.718
3.197AlaIle: 3.197 ± 2.036
10.87AlaLys: 10.87 ± 3.532
4.476AlaLeu: 4.476 ± 2.05
1.918AlaMet: 1.918 ± 0.77
1.918AlaAsn: 1.918 ± 1.274
3.836AlaPro: 3.836 ± 1.513
4.476AlaGln: 4.476 ± 1.606
5.115AlaArg: 5.115 ± 1.555
4.476AlaSer: 4.476 ± 2.652
7.033AlaThr: 7.033 ± 3.36
5.754AlaVal: 5.754 ± 1.823
0.639AlaTrp: 0.639 ± 0.415
2.558AlaTyr: 2.558 ± 0.757
0.0AlaXaa: 0.0 ± 0.0
Cys
0.639CysAla: 0.639 ± 0.599
1.279CysCys: 1.279 ± 0.881
0.0CysAsp: 0.0 ± 0.0
0.639CysGlu: 0.639 ± 0.883
0.0CysPhe: 0.0 ± 0.0
1.918CysGly: 1.918 ± 1.796
0.639CysHis: 0.639 ± 0.599
1.279CysIle: 1.279 ± 0.83
1.279CysLys: 1.279 ± 0.653
1.279CysLeu: 1.279 ± 0.976
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.639CysGln: 0.639 ± 0.415
1.279CysArg: 1.279 ± 1.197
1.918CysSer: 1.918 ± 0.839
0.0CysThr: 0.0 ± 0.0
1.279CysVal: 1.279 ± 1.32
0.0CysTrp: 0.0 ± 0.0
1.279CysTyr: 1.279 ± 0.653
0.0CysXaa: 0.0 ± 0.0
Asp
4.476AspAla: 4.476 ± 1.418
0.639AspCys: 0.639 ± 0.415
7.033AspAsp: 7.033 ± 2.608
3.197AspGlu: 3.197 ± 1.123
3.836AspPhe: 3.836 ± 1.098
4.476AspGly: 4.476 ± 1.823
1.279AspHis: 1.279 ± 0.915
1.279AspIle: 1.279 ± 0.753
3.197AspLys: 3.197 ± 1.841
7.033AspLeu: 7.033 ± 1.343
0.639AspMet: 0.639 ± 0.658
3.836AspAsn: 3.836 ± 2.047
3.836AspPro: 3.836 ± 1.496
2.558AspGln: 2.558 ± 1.299
0.639AspArg: 0.639 ± 0.708
3.836AspSer: 3.836 ± 0.828
1.918AspThr: 1.918 ± 1.328
1.279AspVal: 1.279 ± 0.829
2.558AspTrp: 2.558 ± 1.173
3.836AspTyr: 3.836 ± 1.259
0.0AspXaa: 0.0 ± 0.0
Glu
3.197GluAla: 3.197 ± 2.336
1.279GluCys: 1.279 ± 1.04
3.197GluAsp: 3.197 ± 1.751
7.033GluGlu: 7.033 ± 4.539
7.033GluPhe: 7.033 ± 1.607
3.836GluGly: 3.836 ± 1.405
2.558GluHis: 2.558 ± 1.105
5.115GluIle: 5.115 ± 1.387
3.197GluLys: 3.197 ± 2.015
7.033GluLeu: 7.033 ± 1.447
0.639GluMet: 0.639 ± 0.906
2.558GluAsn: 2.558 ± 0.889
0.639GluPro: 0.639 ± 0.599
1.918GluGln: 1.918 ± 0.988
3.197GluArg: 3.197 ± 1.388
2.558GluSer: 2.558 ± 1.756
1.918GluThr: 1.918 ± 1.039
3.836GluVal: 3.836 ± 1.845
1.918GluTrp: 1.918 ± 1.045
3.197GluTyr: 3.197 ± 1.583
0.0GluXaa: 0.0 ± 0.0
Phe
4.476PheAla: 4.476 ± 2.174
0.0PheCys: 0.0 ± 0.0
1.918PheAsp: 1.918 ± 0.555
2.558PheGlu: 2.558 ± 0.936
0.0PhePhe: 0.0 ± 0.0
2.558PheGly: 2.558 ± 1.306
0.0PheHis: 0.0 ± 0.0
3.836PheIle: 3.836 ± 1.588
1.279PheLys: 1.279 ± 0.954
4.476PheLeu: 4.476 ± 1.071
0.0PheMet: 0.0 ± 0.0
1.918PheAsn: 1.918 ± 0.77
1.918PhePro: 1.918 ± 2.649
0.639PheGln: 0.639 ± 0.676
1.918PheArg: 1.918 ± 1.182
1.918PheSer: 1.918 ± 1.321
6.394PheThr: 6.394 ± 1.462
2.558PheVal: 2.558 ± 0.757
0.0PheTrp: 0.0 ± 0.0
2.558PheTyr: 2.558 ± 1.112
0.0PheXaa: 0.0 ± 0.0
Gly
6.394GlyAla: 6.394 ± 2.278
1.279GlyCys: 1.279 ± 0.653
5.115GlyAsp: 5.115 ± 0.987
5.115GlyGlu: 5.115 ± 1.665
3.197GlyPhe: 3.197 ± 0.977
4.476GlyGly: 4.476 ± 1.901
1.279GlyHis: 1.279 ± 0.942
7.033GlyIle: 7.033 ± 1.618
3.836GlyLys: 3.836 ± 1.345
4.476GlyLeu: 4.476 ± 1.586
1.918GlyMet: 1.918 ± 1.055
3.836GlyAsn: 3.836 ± 1.612
0.639GlyPro: 0.639 ± 0.726
1.918GlyGln: 1.918 ± 1.408
3.197GlyArg: 3.197 ± 2.488
9.591GlySer: 9.591 ± 4.058
5.115GlyThr: 5.115 ± 1.739
3.836GlyVal: 3.836 ± 1.487
0.639GlyTrp: 0.639 ± 0.415
2.558GlyTyr: 2.558 ± 1.14
0.0GlyXaa: 0.0 ± 0.0
His
1.918HisAla: 1.918 ± 0.876
0.639HisCys: 0.639 ± 0.726
1.279HisAsp: 1.279 ± 0.653
0.639HisGlu: 0.639 ± 0.726
0.639HisPhe: 0.639 ± 0.599
0.639HisGly: 0.639 ± 0.969
0.0HisHis: 0.0 ± 0.0
0.639HisIle: 0.639 ± 0.676
1.918HisLys: 1.918 ± 1.041
1.279HisLeu: 1.279 ± 1.197
0.0HisMet: 0.0 ± 0.0
1.918HisAsn: 1.918 ± 0.555
1.918HisPro: 1.918 ± 0.915
0.639HisGln: 0.639 ± 0.415
0.639HisArg: 0.639 ± 0.599
0.639HisSer: 0.639 ± 0.718
1.279HisThr: 1.279 ± 0.829
0.639HisVal: 0.639 ± 0.415
1.279HisTrp: 1.279 ± 0.915
1.918HisTyr: 1.918 ± 1.182
0.0HisXaa: 0.0 ± 0.0
Ile
4.476IleAla: 4.476 ± 1.741
0.639IleCys: 0.639 ± 0.599
1.279IleAsp: 1.279 ± 0.778
5.754IleGlu: 5.754 ± 2.381
0.639IlePhe: 0.639 ± 0.718
5.754IleGly: 5.754 ± 1.869
1.279IleHis: 1.279 ± 0.611
3.197IleIle: 3.197 ± 1.396
3.197IleLys: 3.197 ± 1.204
4.476IleLeu: 4.476 ± 1.248
0.639IleMet: 0.639 ± 0.883
2.558IleAsn: 2.558 ± 1.291
3.197IlePro: 3.197 ± 1.535
3.197IleGln: 3.197 ± 1.071
3.197IleArg: 3.197 ± 2.07
2.558IleSer: 2.558 ± 1.517
2.558IleThr: 2.558 ± 1.143
1.279IleVal: 1.279 ± 0.915
0.639IleTrp: 0.639 ± 0.415
1.279IleTyr: 1.279 ± 0.753
0.0IleXaa: 0.0 ± 0.0
Lys
3.197LysAla: 3.197 ± 2.246
0.639LysCys: 0.639 ± 0.599
3.197LysAsp: 3.197 ± 2.681
8.951LysGlu: 8.951 ± 4.002
0.0LysPhe: 0.0 ± 0.0
7.033LysGly: 7.033 ± 2.21
2.558LysHis: 2.558 ± 1.315
4.476LysIle: 4.476 ± 1.793
3.836LysLys: 3.836 ± 1.877
5.115LysLeu: 5.115 ± 1.792
1.918LysMet: 1.918 ± 0.941
3.197LysAsn: 3.197 ± 1.912
1.918LysPro: 1.918 ± 1.182
1.918LysGln: 1.918 ± 0.919
4.476LysArg: 4.476 ± 2.048
2.558LysSer: 2.558 ± 1.451
3.197LysThr: 3.197 ± 1.984
3.836LysVal: 3.836 ± 1.184
1.279LysTrp: 1.279 ± 0.653
1.918LysTyr: 1.918 ± 0.986
0.0LysXaa: 0.0 ± 0.0
Leu
7.033LeuAla: 7.033 ± 1.646
1.279LeuCys: 1.279 ± 0.954
7.033LeuAsp: 7.033 ± 1.74
4.476LeuGlu: 4.476 ± 1.325
3.836LeuPhe: 3.836 ± 1.838
7.033LeuGly: 7.033 ± 2.38
1.279LeuHis: 1.279 ± 1.197
3.836LeuIle: 3.836 ± 1.183
2.558LeuLys: 2.558 ± 0.819
6.394LeuLeu: 6.394 ± 1.593
1.918LeuMet: 1.918 ± 1.182
4.476LeuAsn: 4.476 ± 1.859
6.394LeuPro: 6.394 ± 2.415
5.754LeuGln: 5.754 ± 1.934
5.754LeuArg: 5.754 ± 1.377
3.197LeuSer: 3.197 ± 0.901
2.558LeuThr: 2.558 ± 1.373
5.115LeuVal: 5.115 ± 1.533
1.918LeuTrp: 1.918 ± 0.555
0.639LeuTyr: 0.639 ± 0.415
0.0LeuXaa: 0.0 ± 0.0
Met
1.279MetAla: 1.279 ± 0.778
0.639MetCys: 0.639 ± 0.883
1.918MetAsp: 1.918 ± 0.988
1.279MetGlu: 1.279 ± 0.915
0.0MetPhe: 0.0 ± 0.0
0.639MetGly: 0.639 ± 0.676
0.0MetHis: 0.0 ± 0.0
1.279MetIle: 1.279 ± 0.653
0.639MetLys: 0.639 ± 0.676
1.918MetLeu: 1.918 ± 0.77
0.639MetMet: 0.639 ± 0.718
0.639MetAsn: 0.639 ± 0.415
0.639MetPro: 0.639 ± 0.883
1.279MetGln: 1.279 ± 0.829
1.918MetArg: 1.918 ± 0.796
4.476MetSer: 4.476 ± 2.246
1.279MetThr: 1.279 ± 1.13
1.279MetVal: 1.279 ± 0.83
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.558AsnAla: 2.558 ± 0.775
0.0AsnCys: 0.0 ± 0.0
1.918AsnAsp: 1.918 ± 0.845
5.754AsnGlu: 5.754 ± 1.366
1.918AsnPhe: 1.918 ± 0.915
1.918AsnGly: 1.918 ± 1.057
0.639AsnHis: 0.639 ± 0.599
2.558AsnIle: 2.558 ± 1.342
1.918AsnLys: 1.918 ± 0.845
5.754AsnLeu: 5.754 ± 1.828
3.197AsnMet: 3.197 ± 1.401
2.558AsnAsn: 2.558 ± 1.582
1.918AsnPro: 1.918 ± 0.93
1.918AsnGln: 1.918 ± 1.101
0.639AsnArg: 0.639 ± 0.415
2.558AsnSer: 2.558 ± 1.658
1.918AsnThr: 1.918 ± 1.944
2.558AsnVal: 2.558 ± 1.351
0.0AsnTrp: 0.0 ± 0.0
1.918AsnTyr: 1.918 ± 0.988
0.0AsnXaa: 0.0 ± 0.0
Pro
4.476ProAla: 4.476 ± 1.655
0.639ProCys: 0.639 ± 0.599
1.279ProAsp: 1.279 ± 1.214
2.558ProGlu: 2.558 ± 1.05
2.558ProPhe: 2.558 ± 1.363
3.836ProGly: 3.836 ± 2.034
1.279ProHis: 1.279 ± 1.197
1.279ProIle: 1.279 ± 0.829
1.918ProLys: 1.918 ± 1.284
5.115ProLeu: 5.115 ± 2.069
0.639ProMet: 0.639 ± 0.415
1.918ProAsn: 1.918 ± 1.762
0.639ProPro: 0.639 ± 0.599
2.558ProGln: 2.558 ± 1.658
0.0ProArg: 0.0 ± 0.0
3.197ProSer: 3.197 ± 1.43
3.197ProThr: 3.197 ± 1.267
4.476ProVal: 4.476 ± 2.902
1.279ProTrp: 1.279 ± 0.829
1.918ProTyr: 1.918 ± 1.262
0.0ProXaa: 0.0 ± 0.0
Gln
5.115GlnAla: 5.115 ± 2.719
0.0GlnCys: 0.0 ± 0.0
0.639GlnAsp: 0.639 ± 0.676
2.558GlnGlu: 2.558 ± 1.525
0.639GlnPhe: 0.639 ± 0.415
3.197GlnGly: 3.197 ± 0.723
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
5.754GlnLys: 5.754 ± 2.379
3.197GlnLeu: 3.197 ± 1.289
1.279GlnMet: 1.279 ± 0.976
3.197GlnAsn: 3.197 ± 1.914
2.558GlnPro: 2.558 ± 1.658
1.279GlnGln: 1.279 ± 0.954
2.558GlnArg: 2.558 ± 1.558
2.558GlnSer: 2.558 ± 1.342
3.197GlnThr: 3.197 ± 0.943
0.639GlnVal: 0.639 ± 0.969
0.0GlnTrp: 0.0 ± 0.0
0.639GlnTyr: 0.639 ± 0.415
0.0GlnXaa: 0.0 ± 0.0
Arg
3.836ArgAla: 3.836 ± 2.521
1.279ArgCys: 1.279 ± 0.653
3.836ArgAsp: 3.836 ± 1.123
2.558ArgGlu: 2.558 ± 0.975
1.918ArgPhe: 1.918 ± 0.796
4.476ArgGly: 4.476 ± 2.192
0.0ArgHis: 0.0 ± 0.0
3.197ArgIle: 3.197 ± 2.138
3.836ArgLys: 3.836 ± 1.351
3.197ArgLeu: 3.197 ± 0.723
1.918ArgMet: 1.918 ± 0.805
1.918ArgAsn: 1.918 ± 1.07
1.918ArgPro: 1.918 ± 1.182
1.279ArgGln: 1.279 ± 1.451
3.836ArgArg: 3.836 ± 1.344
5.115ArgSer: 5.115 ± 1.437
2.558ArgThr: 2.558 ± 0.976
1.918ArgVal: 1.918 ± 0.845
0.639ArgTrp: 0.639 ± 0.599
1.918ArgTyr: 1.918 ± 1.796
0.0ArgXaa: 0.0 ± 0.0
Ser
7.033SerAla: 7.033 ± 2.825
0.0SerCys: 0.0 ± 0.0
3.197SerAsp: 3.197 ± 1.682
3.836SerGlu: 3.836 ± 1.517
3.836SerPhe: 3.836 ± 1.608
5.754SerGly: 5.754 ± 2.547
1.279SerHis: 1.279 ± 0.676
3.836SerIle: 3.836 ± 1.167
5.754SerLys: 5.754 ± 1.74
1.918SerLeu: 1.918 ± 1.244
0.639SerMet: 0.639 ± 0.676
1.918SerAsn: 1.918 ± 0.84
4.476SerPro: 4.476 ± 1.947
1.279SerGln: 1.279 ± 0.618
6.394SerArg: 6.394 ± 1.957
8.312SerSer: 8.312 ± 1.902
7.033SerThr: 7.033 ± 2.392
3.836SerVal: 3.836 ± 0.995
1.918SerTrp: 1.918 ± 1.182
1.279SerTyr: 1.279 ± 0.942
0.0SerXaa: 0.0 ± 0.0
Thr
3.836ThrAla: 3.836 ± 1.775
0.639ThrCys: 0.639 ± 0.599
4.476ThrAsp: 4.476 ± 2.46
3.197ThrGlu: 3.197 ± 1.204
2.558ThrPhe: 2.558 ± 0.931
6.394ThrGly: 6.394 ± 1.92
1.918ThrHis: 1.918 ± 0.986
3.197ThrIle: 3.197 ± 1.237
4.476ThrLys: 4.476 ± 2.06
5.754ThrLeu: 5.754 ± 1.568
1.279ThrMet: 1.279 ± 0.653
0.0ThrAsn: 0.0 ± 0.0
3.836ThrPro: 3.836 ± 0.767
2.558ThrGln: 2.558 ± 1.291
2.558ThrArg: 2.558 ± 0.872
8.951ThrSer: 8.951 ± 2.667
2.558ThrThr: 2.558 ± 1.658
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
3.197ThrTyr: 3.197 ± 1.289
0.0ThrXaa: 0.0 ± 0.0
Val
6.394ValAla: 6.394 ± 1.334
0.639ValCys: 0.639 ± 0.883
0.639ValAsp: 0.639 ± 0.415
0.639ValGlu: 0.639 ± 0.969
1.279ValPhe: 1.279 ± 0.881
5.754ValGly: 5.754 ± 3.483
1.918ValHis: 1.918 ± 1.039
2.558ValIle: 2.558 ± 1.692
3.836ValLys: 3.836 ± 0.767
4.476ValLeu: 4.476 ± 1.723
0.639ValMet: 0.639 ± 0.547
2.558ValAsn: 2.558 ± 1.372
1.279ValPro: 1.279 ± 0.829
0.639ValGln: 0.639 ± 0.676
3.836ValArg: 3.836 ± 1.709
3.197ValSer: 3.197 ± 1.641
3.836ValThr: 3.836 ± 1.619
3.197ValVal: 3.197 ± 1.874
0.0ValTrp: 0.0 ± 0.0
2.558ValTyr: 2.558 ± 1.315
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.279TrpAsp: 1.279 ± 0.618
0.639TrpGlu: 0.639 ± 0.969
1.279TrpPhe: 1.279 ± 1.197
0.639TrpGly: 0.639 ± 0.415
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.279TrpLys: 1.279 ± 0.829
1.279TrpLeu: 1.279 ± 0.653
0.0TrpMet: 0.0 ± 0.0
2.558TrpAsn: 2.558 ± 1.136
1.918TrpPro: 1.918 ± 1.244
0.639TrpGln: 0.639 ± 0.718
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
2.558TrpThr: 2.558 ± 0.645
0.0TrpVal: 0.0 ± 0.0
0.639TrpTrp: 0.639 ± 0.415
1.279TrpTyr: 1.279 ± 0.611
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.197TyrAla: 3.197 ± 1.138
1.918TyrCys: 1.918 ± 0.807
6.394TyrAsp: 6.394 ± 2.128
2.558TyrGlu: 2.558 ± 1.205
1.918TyrPhe: 1.918 ± 0.919
2.558TyrGly: 2.558 ± 0.978
1.918TyrHis: 1.918 ± 1.182
0.0TyrIle: 0.0 ± 0.0
0.639TyrLys: 0.639 ± 0.676
3.836TyrLeu: 3.836 ± 1.47
1.279TyrMet: 1.279 ± 0.829
0.639TyrAsn: 0.639 ± 0.415
1.279TyrPro: 1.279 ± 0.829
1.918TyrGln: 1.918 ± 1.07
0.0TyrArg: 0.0 ± 0.0
1.918TyrSer: 1.918 ± 0.988
1.279TyrThr: 1.279 ± 0.653
2.558TyrVal: 2.558 ± 1.857
0.639TyrTrp: 0.639 ± 0.415
1.279TyrTyr: 1.279 ± 0.829
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski