Amino acid dipepetide frequency for Torque teno canis virus (isolate Cf-TTV10)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.322AlaAla: 16.322 ± 10.288
0.0AlaCys: 0.0 ± 0.0
4.353AlaAsp: 4.353 ± 2.583
2.176AlaGlu: 2.176 ± 2.612
1.088AlaPhe: 1.088 ± 0.646
7.617AlaGly: 7.617 ± 4.594
0.0AlaHis: 0.0 ± 0.0
3.264AlaIle: 3.264 ± 0.9
1.088AlaLys: 1.088 ± 0.646
3.264AlaLeu: 3.264 ± 0.9
3.264AlaMet: 3.264 ± 3.313
0.0AlaAsn: 0.0 ± 0.0
7.617AlaPro: 7.617 ± 0.792
0.0AlaGln: 0.0 ± 0.0
4.353AlaArg: 4.353 ± 1.283
2.176AlaSer: 2.176 ± 1.291
2.176AlaThr: 2.176 ± 1.291
3.264AlaVal: 3.264 ± 2.058
4.353AlaTrp: 4.353 ± 1.574
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.088CysAla: 1.088 ± 0.646
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
4.353CysGly: 4.353 ± 1.574
4.353CysHis: 4.353 ± 5.225
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.088CysLeu: 1.088 ± 0.646
0.0CysMet: 0.0 ± 0.0
2.176CysAsn: 2.176 ± 1.291
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.176CysSer: 2.176 ± 2.612
0.0CysThr: 0.0 ± 0.0
1.088CysVal: 1.088 ± 0.646
1.088CysTrp: 1.088 ± 1.281
1.088CysTyr: 1.088 ± 0.646
0.0CysXaa: 0.0 ± 0.0
Asp
6.529AspAla: 6.529 ± 4.115
1.088AspCys: 1.088 ± 1.281
3.264AspAsp: 3.264 ± 2.058
2.176AspGlu: 2.176 ± 2.612
3.264AspPhe: 3.264 ± 1.937
1.088AspGly: 1.088 ± 0.646
1.088AspHis: 1.088 ± 0.646
1.088AspIle: 1.088 ± 0.646
4.353AspLys: 4.353 ± 2.583
5.441AspLeu: 5.441 ± 3.65
0.0AspMet: 0.0 ± 0.0
1.088AspAsn: 1.088 ± 0.646
6.529AspPro: 6.529 ± 1.401
2.176AspGln: 2.176 ± 1.291
3.264AspArg: 3.264 ± 2.058
4.353AspSer: 4.353 ± 1.798
5.441AspThr: 5.441 ± 3.228
2.176AspVal: 2.176 ± 1.291
4.353AspTrp: 4.353 ± 1.574
2.176AspTyr: 2.176 ± 1.291
0.0AspXaa: 0.0 ± 0.0
Glu
2.176GluAla: 2.176 ± 2.612
2.176GluCys: 2.176 ± 2.612
5.441GluAsp: 5.441 ± 2.033
4.353GluGlu: 4.353 ± 2.583
1.088GluPhe: 1.088 ± 0.646
5.441GluGly: 5.441 ± 2.033
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
1.088GluLys: 1.088 ± 0.646
5.441GluLeu: 5.441 ± 2.033
0.0GluMet: 0.0 ± 0.0
1.088GluAsn: 1.088 ± 0.646
3.264GluPro: 3.264 ± 2.058
1.088GluGln: 1.088 ± 0.646
6.529GluArg: 6.529 ± 4.774
6.529GluSer: 6.529 ± 4.115
6.529GluThr: 6.529 ± 3.012
2.176GluVal: 2.176 ± 0.899
2.176GluTrp: 2.176 ± 1.291
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.088PheAla: 1.088 ± 0.646
0.0PheCys: 0.0 ± 0.0
3.264PheAsp: 3.264 ± 2.058
2.176PheGlu: 2.176 ± 0.899
2.176PhePhe: 2.176 ± 1.291
1.088PheGly: 1.088 ± 0.646
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
2.176PheLys: 2.176 ± 1.291
2.176PheLeu: 2.176 ± 1.291
1.088PheMet: 1.088 ± 0.702
1.088PheAsn: 1.088 ± 0.646
2.176PhePro: 2.176 ± 1.291
0.0PheGln: 0.0 ± 0.0
2.176PheArg: 2.176 ± 1.291
1.088PheSer: 1.088 ± 0.646
0.0PheThr: 0.0 ± 0.0
2.176PheVal: 2.176 ± 1.291
1.088PheTrp: 1.088 ± 0.646
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.353GlyAla: 4.353 ± 1.574
1.088GlyCys: 1.088 ± 0.646
4.353GlyAsp: 4.353 ± 1.574
3.264GlyGlu: 3.264 ± 2.058
1.088GlyPhe: 1.088 ± 1.281
8.705GlyGly: 8.705 ± 3.991
0.0GlyHis: 0.0 ± 0.0
2.176GlyIle: 2.176 ± 1.291
5.441GlyLys: 5.441 ± 3.228
6.529GlyLeu: 6.529 ± 1.401
2.176GlyMet: 2.176 ± 2.021
4.353GlyAsn: 4.353 ± 1.283
6.529GlyPro: 6.529 ± 1.401
1.088GlyGln: 1.088 ± 0.646
2.176GlyArg: 2.176 ± 1.291
3.264GlySer: 3.264 ± 2.058
6.529GlyThr: 6.529 ± 1.211
3.264GlyVal: 3.264 ± 2.116
0.0GlyTrp: 0.0 ± 0.0
5.441GlyTyr: 5.441 ± 1.247
0.0GlyXaa: 0.0 ± 0.0
His
1.088HisAla: 1.088 ± 1.281
4.353HisCys: 4.353 ± 5.225
2.176HisAsp: 2.176 ± 2.612
2.176HisGlu: 2.176 ± 2.612
0.0HisPhe: 0.0 ± 0.0
2.176HisGly: 2.176 ± 2.612
0.0HisHis: 0.0 ± 0.0
1.088HisIle: 1.088 ± 0.646
1.088HisLys: 1.088 ± 0.646
4.353HisLeu: 4.353 ± 1.574
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.176HisPro: 2.176 ± 1.291
1.088HisGln: 1.088 ± 0.646
1.088HisArg: 1.088 ± 0.646
1.088HisSer: 1.088 ± 0.646
3.264HisThr: 3.264 ± 1.937
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.353IleAla: 4.353 ± 2.583
0.0IleCys: 0.0 ± 0.0
1.088IleAsp: 1.088 ± 0.646
1.088IleGlu: 1.088 ± 0.646
1.088IlePhe: 1.088 ± 0.646
0.0IleGly: 0.0 ± 0.0
1.088IleHis: 1.088 ± 0.646
0.0IleIle: 0.0 ± 0.0
3.264IleLys: 3.264 ± 1.937
2.176IleLeu: 2.176 ± 1.291
3.264IleMet: 3.264 ± 1.937
1.088IleAsn: 1.088 ± 0.646
3.264IlePro: 3.264 ± 1.937
1.088IleGln: 1.088 ± 0.646
1.088IleArg: 1.088 ± 1.281
2.176IleSer: 2.176 ± 1.291
2.176IleThr: 2.176 ± 1.291
1.088IleVal: 1.088 ± 0.646
1.088IleTrp: 1.088 ± 0.646
2.176IleTyr: 2.176 ± 1.291
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.176LysAsp: 2.176 ± 0.899
4.353LysGlu: 4.353 ± 1.574
0.0LysPhe: 0.0 ± 0.0
4.353LysGly: 4.353 ± 1.283
1.088LysHis: 1.088 ± 0.646
2.176LysIle: 2.176 ± 1.291
8.705LysLys: 8.705 ± 1.947
2.176LysLeu: 2.176 ± 1.291
1.088LysMet: 1.088 ± 0.527
0.0LysAsn: 0.0 ± 0.0
5.441LysPro: 5.441 ± 3.228
5.441LysGln: 5.441 ± 1.247
4.353LysArg: 4.353 ± 2.672
4.353LysSer: 4.353 ± 2.672
1.088LysThr: 1.088 ± 0.646
3.264LysVal: 3.264 ± 1.937
5.441LysTrp: 5.441 ± 3.228
1.088LysTyr: 1.088 ± 0.646
0.0LysXaa: 0.0 ± 0.0
Leu
5.441LeuAla: 5.441 ± 1.247
2.176LeuCys: 2.176 ± 1.291
3.264LeuAsp: 3.264 ± 1.937
3.264LeuGlu: 3.264 ± 2.116
1.088LeuPhe: 1.088 ± 0.646
5.441LeuGly: 5.441 ± 1.821
0.0LeuHis: 0.0 ± 0.0
1.088LeuIle: 1.088 ± 0.646
6.529LeuLys: 6.529 ± 1.211
6.529LeuLeu: 6.529 ± 2.412
3.264LeuMet: 3.264 ± 1.937
2.176LeuAsn: 2.176 ± 0.899
2.176LeuPro: 2.176 ± 0.899
0.0LeuGln: 0.0 ± 0.0
3.264LeuArg: 3.264 ± 0.9
3.264LeuSer: 3.264 ± 1.937
4.353LeuThr: 4.353 ± 1.798
6.529LeuVal: 6.529 ± 5.208
3.264LeuTrp: 3.264 ± 2.058
2.176LeuTyr: 2.176 ± 0.899
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.088MetAsp: 1.088 ± 0.646
1.088MetGlu: 1.088 ± 0.646
0.0MetPhe: 0.0 ± 0.0
1.088MetGly: 1.088 ± 0.646
1.088MetHis: 1.088 ± 0.646
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
5.441MetLeu: 5.441 ± 2.033
1.088MetMet: 1.088 ± 0.646
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.088MetGln: 1.088 ± 0.646
1.088MetArg: 1.088 ± 0.646
4.353MetSer: 4.353 ± 1.574
3.264MetThr: 3.264 ± 0.9
0.0MetVal: 0.0 ± 0.0
1.088MetTrp: 1.088 ± 1.281
1.088MetTyr: 1.088 ± 0.646
0.0MetXaa: 0.0 ± 0.0
Asn
1.088AsnAla: 1.088 ± 0.646
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.088AsnGlu: 1.088 ± 0.646
1.088AsnPhe: 1.088 ± 0.646
1.088AsnGly: 1.088 ± 0.646
0.0AsnHis: 0.0 ± 0.0
1.088AsnIle: 1.088 ± 0.646
0.0AsnLys: 0.0 ± 0.0
1.088AsnLeu: 1.088 ± 0.646
0.0AsnMet: 0.0 ± 0.0
2.176AsnAsn: 2.176 ± 0.899
6.529AsnPro: 6.529 ± 3.874
2.176AsnGln: 2.176 ± 0.899
4.353AsnArg: 4.353 ± 3.381
5.441AsnSer: 5.441 ± 1.679
3.264AsnThr: 3.264 ± 1.937
1.088AsnVal: 1.088 ± 0.646
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.529ProAla: 6.529 ± 1.401
2.176ProCys: 2.176 ± 1.291
2.176ProAsp: 2.176 ± 2.612
6.529ProGlu: 6.529 ± 1.8
3.264ProPhe: 3.264 ± 0.9
8.705ProGly: 8.705 ± 3.991
1.088ProHis: 1.088 ± 0.646
2.176ProIle: 2.176 ± 1.291
5.441ProLys: 5.441 ± 1.821
2.176ProLeu: 2.176 ± 0.899
1.088ProMet: 1.088 ± 0.646
3.264ProAsn: 3.264 ± 1.937
8.705ProPro: 8.705 ± 2.54
4.353ProGln: 4.353 ± 1.283
8.705ProArg: 8.705 ± 2.54
1.088ProSer: 1.088 ± 1.281
5.441ProThr: 5.441 ± 2.033
0.0ProVal: 0.0 ± 0.0
4.353ProTrp: 4.353 ± 1.574
3.264ProTyr: 3.264 ± 1.937
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
3.264GlnAsp: 3.264 ± 1.937
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.176GlnGly: 2.176 ± 1.291
3.264GlnHis: 3.264 ± 2.058
5.441GlnIle: 5.441 ± 3.228
0.0GlnLys: 0.0 ± 0.0
2.176GlnLeu: 2.176 ± 1.291
0.0GlnMet: 0.0 ± 0.0
1.088GlnAsn: 1.088 ± 1.281
4.353GlnPro: 4.353 ± 1.798
1.088GlnGln: 1.088 ± 0.646
1.088GlnArg: 1.088 ± 0.646
1.088GlnSer: 1.088 ± 0.646
3.264GlnThr: 3.264 ± 0.9
0.0GlnVal: 0.0 ± 0.0
2.176GlnTrp: 2.176 ± 1.291
2.176GlnTyr: 2.176 ± 0.899
0.0GlnXaa: 0.0 ± 0.0
Arg
6.529ArgAla: 6.529 ± 2.697
0.0ArgCys: 0.0 ± 0.0
4.353ArgAsp: 4.353 ± 3.381
9.793ArgGlu: 9.793 ± 7.192
1.088ArgPhe: 1.088 ± 0.646
3.264ArgGly: 3.264 ± 1.937
5.441ArgHis: 5.441 ± 4.658
1.088ArgIle: 1.088 ± 0.646
3.264ArgLys: 3.264 ± 0.9
2.176ArgLeu: 2.176 ± 1.291
1.088ArgMet: 1.088 ± 0.646
3.264ArgAsn: 3.264 ± 2.116
4.353ArgPro: 4.353 ± 1.798
3.264ArgGln: 3.264 ± 1.937
26.115ArgArg: 26.115 ± 7.698
2.176ArgSer: 2.176 ± 0.899
2.176ArgThr: 2.176 ± 2.561
1.088ArgVal: 1.088 ± 0.646
6.529ArgTrp: 6.529 ± 1.211
4.353ArgTyr: 4.353 ± 2.583
0.0ArgXaa: 0.0 ± 0.0
Ser
3.264SerAla: 3.264 ± 2.058
0.0SerCys: 0.0 ± 0.0
5.441SerAsp: 5.441 ± 2.033
4.353SerGlu: 4.353 ± 1.798
4.353SerPhe: 4.353 ± 1.574
5.441SerGly: 5.441 ± 4.658
4.353SerHis: 4.353 ± 1.574
3.264SerIle: 3.264 ± 1.937
3.264SerLys: 3.264 ± 2.058
2.176SerLeu: 2.176 ± 0.899
1.088SerMet: 1.088 ± 0.646
2.176SerAsn: 2.176 ± 0.899
3.264SerPro: 3.264 ± 2.058
2.176SerGln: 2.176 ± 0.899
1.088SerArg: 1.088 ± 0.646
6.529SerSer: 6.529 ± 2.697
7.617SerThr: 7.617 ± 2.12
0.0SerVal: 0.0 ± 0.0
5.441SerTrp: 5.441 ± 2.033
4.353SerTyr: 4.353 ± 1.798
0.0SerXaa: 0.0 ± 0.0
Thr
4.353ThrAla: 4.353 ± 1.283
1.088ThrCys: 1.088 ± 0.646
3.264ThrAsp: 3.264 ± 1.937
5.441ThrGlu: 5.441 ± 1.247
0.0ThrPhe: 0.0 ± 0.0
3.264ThrGly: 3.264 ± 0.9
4.353ThrHis: 4.353 ± 1.283
2.176ThrIle: 2.176 ± 1.291
2.176ThrLys: 2.176 ± 1.291
4.353ThrLeu: 4.353 ± 1.283
0.0ThrMet: 0.0 ± 0.0
3.264ThrAsn: 3.264 ± 1.937
8.705ThrPro: 8.705 ± 3.552
3.264ThrGln: 3.264 ± 0.9
8.705ThrArg: 8.705 ± 5.344
6.529ThrSer: 6.529 ± 2.697
7.617ThrThr: 7.617 ± 5.961
0.0ThrVal: 0.0 ± 0.0
1.088ThrTrp: 1.088 ± 0.646
2.176ThrTyr: 2.176 ± 1.291
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.353ValAsp: 4.353 ± 1.574
3.264ValGlu: 3.264 ± 3.313
1.088ValPhe: 1.088 ± 0.646
2.176ValGly: 2.176 ± 1.291
0.0ValHis: 0.0 ± 0.0
2.176ValIle: 2.176 ± 1.291
2.176ValLys: 2.176 ± 1.291
1.088ValLeu: 1.088 ± 0.646
1.088ValMet: 1.088 ± 0.646
0.0ValAsn: 0.0 ± 0.0
1.088ValPro: 1.088 ± 1.281
0.0ValGln: 0.0 ± 0.0
2.176ValArg: 2.176 ± 1.291
4.353ValSer: 4.353 ± 2.672
1.088ValThr: 1.088 ± 1.281
0.0ValVal: 0.0 ± 0.0
2.176ValTrp: 2.176 ± 1.291
1.088ValTyr: 1.088 ± 0.646
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
4.353TrpCys: 4.353 ± 1.574
3.264TrpAsp: 3.264 ± 1.937
0.0TrpGlu: 0.0 ± 0.0
2.176TrpPhe: 2.176 ± 1.291
3.264TrpGly: 3.264 ± 1.937
0.0TrpHis: 0.0 ± 0.0
1.088TrpIle: 1.088 ± 0.646
5.441TrpLys: 5.441 ± 5.828
3.264TrpLeu: 3.264 ± 1.937
1.088TrpMet: 1.088 ± 1.281
3.264TrpAsn: 3.264 ± 1.937
3.264TrpPro: 3.264 ± 0.9
1.088TrpGln: 1.088 ± 0.646
3.264TrpArg: 3.264 ± 1.937
6.529TrpSer: 6.529 ± 4.115
3.264TrpThr: 3.264 ± 2.058
1.088TrpVal: 1.088 ± 0.646
1.088TrpTrp: 1.088 ± 0.646
2.176TrpTyr: 2.176 ± 1.291
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.176TyrAla: 2.176 ± 1.291
0.0TyrCys: 0.0 ± 0.0
4.353TyrAsp: 4.353 ± 2.583
0.0TyrGlu: 0.0 ± 0.0
2.176TyrPhe: 2.176 ± 1.291
1.088TyrGly: 1.088 ± 0.646
0.0TyrHis: 0.0 ± 0.0
3.264TyrIle: 3.264 ± 1.937
1.088TyrLys: 1.088 ± 1.281
2.176TyrLeu: 2.176 ± 0.899
1.088TyrMet: 1.088 ± 0.646
0.0TyrAsn: 0.0 ± 0.0
1.088TyrPro: 1.088 ± 0.646
2.176TyrGln: 2.176 ± 0.899
6.529TyrArg: 6.529 ± 1.211
1.088TyrSer: 1.088 ± 0.646
3.264TyrThr: 3.264 ± 0.9
1.088TyrVal: 1.088 ± 0.646
2.176TyrTrp: 2.176 ± 1.291
5.441TyrTyr: 5.441 ± 3.228
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (920 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski