Amino acid dipepetide frequency for Malvastrum yellow vein virus-[Y47]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.484AlaAla: 4.484 ± 2.468
1.794AlaCys: 1.794 ± 0.698
0.897AlaAsp: 0.897 ± 0.729
0.897AlaGlu: 0.897 ± 0.658
0.0AlaPhe: 0.0 ± 0.0
1.794AlaGly: 1.794 ± 1.141
1.794AlaHis: 1.794 ± 0.946
4.484AlaIle: 4.484 ± 2.118
4.484AlaLys: 4.484 ± 1.077
6.278AlaLeu: 6.278 ± 1.923
0.897AlaMet: 0.897 ± 0.905
2.691AlaAsn: 2.691 ± 1.011
0.897AlaPro: 0.897 ± 0.658
4.484AlaGln: 4.484 ± 1.322
2.691AlaArg: 2.691 ± 1.974
4.484AlaSer: 4.484 ± 2.248
3.587AlaThr: 3.587 ± 2.918
0.0AlaVal: 0.0 ± 0.0
2.691AlaTrp: 2.691 ± 1.382
1.794AlaTyr: 1.794 ± 1.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.897CysCys: 0.897 ± 0.873
0.0CysAsp: 0.0 ± 0.0
1.794CysGlu: 1.794 ± 0.698
0.897CysPhe: 0.897 ± 1.091
1.794CysGly: 1.794 ± 0.894
0.0CysHis: 0.0 ± 0.0
0.897CysIle: 0.897 ± 0.729
0.897CysLys: 0.897 ± 0.729
0.0CysLeu: 0.0 ± 0.0
1.794CysMet: 1.794 ± 1.298
3.587CysAsn: 3.587 ± 1.724
1.794CysPro: 1.794 ± 1.807
1.794CysGln: 1.794 ± 1.316
1.794CysArg: 1.794 ± 0.946
2.691CysSer: 2.691 ± 1.641
1.794CysThr: 1.794 ± 1.031
0.897CysVal: 0.897 ± 0.729
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.691AspAla: 2.691 ± 1.974
0.0AspCys: 0.0 ± 0.0
2.691AspAsp: 2.691 ± 1.094
2.691AspGlu: 2.691 ± 0.788
1.794AspPhe: 1.794 ± 0.698
1.794AspGly: 1.794 ± 1.316
1.794AspHis: 1.794 ± 0.894
2.691AspIle: 2.691 ± 0.907
0.0AspLys: 0.0 ± 0.0
6.278AspLeu: 6.278 ± 2.479
1.794AspMet: 1.794 ± 1.34
1.794AspAsn: 1.794 ± 1.172
3.587AspPro: 3.587 ± 1.724
1.794AspGln: 1.794 ± 1.008
2.691AspArg: 2.691 ± 1.267
3.587AspSer: 3.587 ± 1.447
1.794AspThr: 1.794 ± 0.946
6.278AspVal: 6.278 ± 2.465
1.794AspTrp: 1.794 ± 0.894
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.381GluAla: 5.381 ± 1.373
0.897GluCys: 0.897 ± 0.873
0.0GluAsp: 0.0 ± 0.0
6.278GluGlu: 6.278 ± 3.872
3.587GluPhe: 3.587 ± 1.496
4.484GluGly: 4.484 ± 1.712
0.897GluHis: 0.897 ± 0.873
0.897GluIle: 0.897 ± 1.091
1.794GluLys: 1.794 ± 1.316
5.381GluLeu: 5.381 ± 1.889
0.0GluMet: 0.0 ± 0.0
5.381GluAsn: 5.381 ± 1.964
2.691GluPro: 2.691 ± 1.384
2.691GluGln: 2.691 ± 1.384
0.0GluArg: 0.0 ± 0.0
2.691GluSer: 2.691 ± 0.788
2.691GluThr: 2.691 ± 1.236
0.897GluVal: 0.897 ± 0.905
0.897GluTrp: 0.897 ± 0.873
0.897GluTyr: 0.897 ± 0.658
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.897PheCys: 0.897 ± 0.729
3.587PheAsp: 3.587 ± 1.396
1.794PheGlu: 1.794 ± 0.698
1.794PhePhe: 1.794 ± 0.698
0.897PheGly: 0.897 ± 0.729
1.794PheHis: 1.794 ± 1.316
0.897PheIle: 0.897 ± 0.658
3.587PheLys: 3.587 ± 2.114
10.762PheLeu: 10.762 ± 3.536
0.897PheMet: 0.897 ± 0.658
2.691PheAsn: 2.691 ± 2.144
0.897PhePro: 0.897 ± 0.903
1.794PheGln: 1.794 ± 0.894
1.794PheArg: 1.794 ± 1.298
2.691PheSer: 2.691 ± 1.914
2.691PheThr: 2.691 ± 1.228
2.691PheVal: 2.691 ± 1.144
0.0PheTrp: 0.0 ± 0.0
1.794PheTyr: 1.794 ± 1.111
0.0PheXaa: 0.0 ± 0.0
Gly
5.381GlyAla: 5.381 ± 0.801
2.691GlyCys: 2.691 ± 0.788
2.691GlyAsp: 2.691 ± 1.144
1.794GlyGlu: 1.794 ± 1.359
1.794GlyPhe: 1.794 ± 1.22
2.691GlyGly: 2.691 ± 1.144
1.794GlyHis: 1.794 ± 0.894
2.691GlyIle: 2.691 ± 1.305
6.278GlyLys: 6.278 ± 2.584
2.691GlyLeu: 2.691 ± 1.352
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
4.484GlyPro: 4.484 ± 1.75
1.794GlyGln: 1.794 ± 1.141
0.897GlyArg: 0.897 ± 0.658
3.587GlySer: 3.587 ± 1.863
3.587GlyThr: 3.587 ± 1.227
1.794GlyVal: 1.794 ± 2.182
0.0GlyTrp: 0.0 ± 0.0
1.794GlyTyr: 1.794 ± 1.807
0.0GlyXaa: 0.0 ± 0.0
His
0.897HisAla: 0.897 ± 0.729
2.691HisCys: 2.691 ± 1.92
2.691HisAsp: 2.691 ± 1.389
1.794HisGlu: 1.794 ± 0.946
3.587HisPhe: 3.587 ± 1.911
3.587HisGly: 3.587 ± 1.724
1.794HisHis: 1.794 ± 1.747
1.794HisIle: 1.794 ± 1.141
2.691HisLys: 2.691 ± 1.594
1.794HisLeu: 1.794 ± 1.316
0.897HisMet: 0.897 ± 0.905
2.691HisAsn: 2.691 ± 1.305
2.691HisPro: 2.691 ± 1.176
0.0HisGln: 0.0 ± 0.0
3.587HisArg: 3.587 ± 2.061
0.897HisSer: 0.897 ± 0.729
0.897HisThr: 0.897 ± 0.729
1.794HisVal: 1.794 ± 1.057
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.897IleCys: 0.897 ± 0.658
0.897IleAsp: 0.897 ± 0.658
1.794IleGlu: 1.794 ± 1.057
3.587IlePhe: 3.587 ± 2.632
0.897IleGly: 0.897 ± 0.729
0.897IleHis: 0.897 ± 0.873
1.794IleIle: 1.794 ± 2.182
6.278IleLys: 6.278 ± 1.035
4.484IleLeu: 4.484 ± 2.063
0.897IleMet: 0.897 ± 0.905
4.484IleAsn: 4.484 ± 2.118
0.897IlePro: 0.897 ± 0.658
6.278IleGln: 6.278 ± 2.093
4.484IleArg: 4.484 ± 1.888
7.175IleSer: 7.175 ± 2.651
1.794IleThr: 1.794 ± 2.182
1.794IleVal: 1.794 ± 0.698
2.691IleTrp: 2.691 ± 2.144
1.794IleTyr: 1.794 ± 1.141
0.0IleXaa: 0.0 ± 0.0
Lys
2.691LysAla: 2.691 ± 1.442
2.691LysCys: 2.691 ± 1.382
3.587LysAsp: 3.587 ± 1.863
5.381LysGlu: 5.381 ± 2.319
4.484LysPhe: 4.484 ± 1.522
1.794LysGly: 1.794 ± 0.894
0.897LysHis: 0.897 ± 0.658
3.587LysIle: 3.587 ± 1.746
3.587LysLys: 3.587 ± 1.022
0.0LysLeu: 0.0 ± 0.0
0.897LysMet: 0.897 ± 0.905
4.484LysAsn: 4.484 ± 1.777
2.691LysPro: 2.691 ± 1.011
0.897LysGln: 0.897 ± 0.905
3.587LysArg: 3.587 ± 1.716
7.175LysSer: 7.175 ± 2.169
4.484LysThr: 4.484 ± 1.9
4.484LysVal: 4.484 ± 1.859
0.897LysTrp: 0.897 ± 0.729
3.587LysTyr: 3.587 ± 1.005
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.794LeuCys: 1.794 ± 1.316
5.381LeuAsp: 5.381 ± 2.609
3.587LeuGlu: 3.587 ± 1.365
1.794LeuPhe: 1.794 ± 1.406
4.484LeuGly: 4.484 ± 1.929
2.691LeuHis: 2.691 ± 1.382
4.484LeuIle: 4.484 ± 2.007
7.175LeuLys: 7.175 ± 1.631
2.691LeuLeu: 2.691 ± 2.045
0.897LeuMet: 0.897 ± 0.729
4.484LeuAsn: 4.484 ± 1.624
2.691LeuPro: 2.691 ± 1.514
4.484LeuGln: 4.484 ± 1.77
6.278LeuArg: 6.278 ± 3.31
5.381LeuSer: 5.381 ± 1.633
8.072LeuThr: 8.072 ± 1.881
2.691LeuVal: 2.691 ± 1.648
0.897LeuTrp: 0.897 ± 1.091
4.484LeuTyr: 4.484 ± 1.929
0.0LeuXaa: 0.0 ± 0.0
Met
0.897MetAla: 0.897 ± 0.729
0.897MetCys: 0.897 ± 0.729
3.587MetAsp: 3.587 ± 2.176
1.794MetGlu: 1.794 ± 1.181
2.691MetPhe: 2.691 ± 1.689
1.794MetGly: 1.794 ± 1.008
0.897MetHis: 0.897 ± 0.729
0.897MetIle: 0.897 ± 0.903
0.897MetLys: 0.897 ± 0.905
0.897MetLeu: 0.897 ± 0.729
0.0MetMet: 0.0 ± 0.0
1.794MetAsn: 1.794 ± 1.172
1.794MetPro: 1.794 ± 1.008
0.0MetGln: 0.0 ± 0.0
0.897MetArg: 0.897 ± 0.873
1.794MetSer: 1.794 ± 1.141
0.897MetThr: 0.897 ± 1.091
0.0MetVal: 0.0 ± 0.0
2.691MetTrp: 2.691 ± 0.914
2.691MetTyr: 2.691 ± 1.619
0.0MetXaa: 0.0 ± 0.0
Asn
4.484AsnAla: 4.484 ± 1.059
1.794AsnCys: 1.794 ± 1.22
1.794AsnAsp: 1.794 ± 1.316
1.794AsnGlu: 1.794 ± 1.111
0.897AsnPhe: 0.897 ± 0.729
0.897AsnGly: 0.897 ± 0.658
3.587AsnHis: 3.587 ± 1.716
2.691AsnIle: 2.691 ± 1.144
0.0AsnLys: 0.0 ± 0.0
8.072AsnLeu: 8.072 ± 3.108
3.587AsnMet: 3.587 ± 2.174
3.587AsnAsn: 3.587 ± 1.227
4.484AsnPro: 4.484 ± 1.038
2.691AsnGln: 2.691 ± 0.788
4.484AsnArg: 4.484 ± 1.232
3.587AsnSer: 3.587 ± 2.003
0.897AsnThr: 0.897 ± 0.658
4.484AsnVal: 4.484 ± 1.712
0.897AsnTrp: 0.897 ± 0.658
4.484AsnTyr: 4.484 ± 0.985
0.0AsnXaa: 0.0 ± 0.0
Pro
2.691ProAla: 2.691 ± 1.557
1.794ProCys: 1.794 ± 1.111
1.794ProAsp: 1.794 ± 1.111
1.794ProGlu: 1.794 ± 0.946
1.794ProPhe: 1.794 ± 1.057
0.897ProGly: 0.897 ± 0.658
3.587ProHis: 3.587 ± 1.911
2.691ProIle: 2.691 ± 2.071
4.484ProLys: 4.484 ± 2.609
6.278ProLeu: 6.278 ± 1.95
0.897ProMet: 0.897 ± 0.729
3.587ProAsn: 3.587 ± 1.38
0.897ProPro: 0.897 ± 0.658
6.278ProGln: 6.278 ± 1.449
6.278ProArg: 6.278 ± 2.36
6.278ProSer: 6.278 ± 3.157
5.381ProThr: 5.381 ± 2.023
1.794ProVal: 1.794 ± 0.698
0.0ProTrp: 0.0 ± 0.0
0.897ProTyr: 0.897 ± 0.729
0.0ProXaa: 0.0 ± 0.0
Gln
4.484GlnAla: 4.484 ± 2.135
0.0GlnCys: 0.0 ± 0.0
3.587GlnAsp: 3.587 ± 1.907
1.794GlnGlu: 1.794 ± 0.698
3.587GlnPhe: 3.587 ± 1.889
3.587GlnGly: 3.587 ± 2.003
1.794GlnHis: 1.794 ± 1.181
0.897GlnIle: 0.897 ± 0.658
0.897GlnLys: 0.897 ± 0.903
2.691GlnLeu: 2.691 ± 1.473
0.0GlnMet: 0.0 ± 0.0
2.691GlnAsn: 2.691 ± 1.082
4.484GlnPro: 4.484 ± 2.51
1.794GlnGln: 1.794 ± 0.698
1.794GlnArg: 1.794 ± 1.008
5.381GlnSer: 5.381 ± 2.319
3.587GlnThr: 3.587 ± 1.317
6.278GlnVal: 6.278 ± 2.236
0.0GlnTrp: 0.0 ± 0.0
0.897GlnTyr: 0.897 ± 0.729
0.0GlnXaa: 0.0 ± 0.0
Arg
2.691ArgAla: 2.691 ± 2.144
1.794ArgCys: 1.794 ± 1.22
2.691ArgAsp: 2.691 ± 1.267
3.587ArgGlu: 3.587 ± 1.272
1.794ArgPhe: 1.794 ± 0.698
3.587ArgGly: 3.587 ± 1.227
2.691ArgHis: 2.691 ± 1.889
5.381ArgIle: 5.381 ± 2.817
2.691ArgLys: 2.691 ± 1.689
1.794ArgLeu: 1.794 ± 1.031
2.691ArgMet: 2.691 ± 2.188
1.794ArgAsn: 1.794 ± 1.22
6.278ArgPro: 6.278 ± 1.635
2.691ArgGln: 2.691 ± 1.473
6.278ArgArg: 6.278 ± 3.127
6.278ArgSer: 6.278 ± 1.921
2.691ArgThr: 2.691 ± 2.045
5.381ArgVal: 5.381 ± 2.29
0.0ArgTrp: 0.0 ± 0.0
1.794ArgTyr: 1.794 ± 1.111
0.0ArgXaa: 0.0 ± 0.0
Ser
3.587SerAla: 3.587 ± 1.863
0.897SerCys: 0.897 ± 0.903
3.587SerAsp: 3.587 ± 1.51
5.381SerGlu: 5.381 ± 1.675
2.691SerPhe: 2.691 ± 0.788
3.587SerGly: 3.587 ± 1.38
2.691SerHis: 2.691 ± 1.514
8.072SerIle: 8.072 ± 2.827
8.072SerLys: 8.072 ± 3.125
3.587SerLeu: 3.587 ± 2.016
2.691SerMet: 2.691 ± 1.294
6.278SerAsn: 6.278 ± 2.172
8.072SerPro: 8.072 ± 2.077
0.897SerGln: 0.897 ± 0.658
6.278SerArg: 6.278 ± 1.304
13.453SerSer: 13.453 ± 4.488
3.587SerThr: 3.587 ± 1.946
1.794SerVal: 1.794 ± 1.459
0.0SerTrp: 0.0 ± 0.0
1.794SerTyr: 1.794 ± 0.894
0.0SerXaa: 0.0 ± 0.0
Thr
3.587ThrAla: 3.587 ± 1.066
0.897ThrCys: 0.897 ± 0.905
0.897ThrAsp: 0.897 ± 0.905
0.897ThrGlu: 0.897 ± 0.905
0.897ThrPhe: 0.897 ± 0.905
5.381ThrGly: 5.381 ± 2.333
4.484ThrHis: 4.484 ± 2.145
2.691ThrIle: 2.691 ± 2.045
2.691ThrLys: 2.691 ± 1.144
2.691ThrLeu: 2.691 ± 1.011
2.691ThrMet: 2.691 ± 2.045
2.691ThrAsn: 2.691 ± 1.619
5.381ThrPro: 5.381 ± 1.505
3.587ThrGln: 3.587 ± 1.311
1.794ThrArg: 1.794 ± 1.459
4.484ThrSer: 4.484 ± 1.9
1.794ThrThr: 1.794 ± 1.809
5.381ThrVal: 5.381 ± 3.296
0.0ThrTrp: 0.0 ± 0.0
2.691ThrTyr: 2.691 ± 1.382
0.0ThrXaa: 0.0 ± 0.0
Val
0.897ValAla: 0.897 ± 0.905
0.0ValCys: 0.0 ± 0.0
4.484ValAsp: 4.484 ± 1.779
1.794ValGlu: 1.794 ± 1.807
2.691ValPhe: 2.691 ± 1.389
2.691ValGly: 2.691 ± 1.889
2.691ValHis: 2.691 ± 1.384
3.587ValIle: 3.587 ± 1.066
3.587ValLys: 3.587 ± 1.946
4.484ValLeu: 4.484 ± 1.829
1.794ValMet: 1.794 ± 1.459
1.794ValAsn: 1.794 ± 1.111
3.587ValPro: 3.587 ± 1.227
4.484ValGln: 4.484 ± 1.664
4.484ValArg: 4.484 ± 3.647
0.897ValSer: 0.897 ± 0.873
4.484ValThr: 4.484 ± 2.652
3.587ValVal: 3.587 ± 1.946
0.0ValTrp: 0.0 ± 0.0
3.587ValTyr: 3.587 ± 1.946
0.0ValXaa: 0.0 ± 0.0
Trp
3.587TrpAla: 3.587 ± 1.731
0.0TrpCys: 0.0 ± 0.0
0.897TrpAsp: 0.897 ± 0.903
0.897TrpGlu: 0.897 ± 1.091
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.897TrpLys: 0.897 ± 1.091
0.0TrpLeu: 0.0 ± 0.0
0.897TrpMet: 0.897 ± 0.729
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.897TrpGln: 0.897 ± 0.658
0.897TrpArg: 0.897 ± 0.873
1.794TrpSer: 1.794 ± 1.406
0.897TrpThr: 0.897 ± 1.091
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.794TrpTyr: 1.794 ± 0.698
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.691TyrAla: 2.691 ± 1.267
0.0TyrCys: 0.0 ± 0.0
1.794TyrAsp: 1.794 ± 1.111
0.897TyrGlu: 0.897 ± 0.729
3.587TyrPhe: 3.587 ± 0.99
1.794TyrGly: 1.794 ± 0.698
0.0TyrHis: 0.0 ± 0.0
2.691TyrIle: 2.691 ± 1.382
0.897TyrLys: 0.897 ± 0.658
3.587TyrLeu: 3.587 ± 1.311
2.691TyrMet: 2.691 ± 1.233
2.691TyrAsn: 2.691 ± 0.907
1.794TyrPro: 1.794 ± 0.946
0.897TyrGln: 0.897 ± 0.729
3.587TyrArg: 3.587 ± 1.746
3.587TyrSer: 3.587 ± 1.142
0.0TyrThr: 0.0 ± 0.0
3.587TyrVal: 3.587 ± 1.746
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1116 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski