Amino acid dipepetide frequency for Hubei permutotetra-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.945AlaAla: 4.945 ± 1.088
0.0AlaCys: 0.0 ± 0.0
3.297AlaAsp: 3.297 ± 2.547
4.396AlaGlu: 4.396 ± 1.599
2.747AlaPhe: 2.747 ± 0.697
7.143AlaGly: 7.143 ± 1.996
1.099AlaHis: 1.099 ± 0.513
1.648AlaIle: 1.648 ± 0.363
6.044AlaLys: 6.044 ± 3.312
4.945AlaLeu: 4.945 ± 2.149
0.549AlaMet: 0.549 ± 0.321
0.549AlaAsn: 0.549 ± 0.321
3.297AlaPro: 3.297 ± 0.973
0.549AlaGln: 0.549 ± 0.774
6.044AlaArg: 6.044 ± 4.186
4.396AlaSer: 4.396 ± 1.171
3.297AlaThr: 3.297 ± 1.538
4.945AlaVal: 4.945 ± 1.913
1.648AlaTrp: 1.648 ± 0.363
1.099AlaTyr: 1.099 ± 0.641
0.0AlaXaa: 0.0 ± 0.0
Cys
1.099CysAla: 1.099 ± 1.316
1.099CysCys: 1.099 ± 1.316
1.648CysAsp: 1.648 ± 0.962
2.198CysGlu: 2.198 ± 1.025
1.099CysPhe: 1.099 ± 0.513
1.099CysGly: 1.099 ± 0.513
0.549CysHis: 0.549 ± 0.321
0.549CysIle: 0.549 ± 0.774
1.648CysLys: 1.648 ± 0.962
0.549CysLeu: 0.549 ± 0.96
0.549CysMet: 0.549 ± 0.321
0.0CysAsn: 0.0 ± 0.0
2.198CysPro: 2.198 ± 2.636
0.0CysGln: 0.0 ± 0.0
1.099CysArg: 1.099 ± 0.641
1.099CysSer: 1.099 ± 0.641
0.0CysThr: 0.0 ± 0.0
1.648CysVal: 1.648 ± 0.783
0.0CysTrp: 0.0 ± 0.0
0.549CysTyr: 0.549 ± 0.321
0.0CysXaa: 0.0 ± 0.0
Asp
2.198AspAla: 2.198 ± 1.025
2.198AspCys: 2.198 ± 0.737
0.549AspAsp: 0.549 ± 0.321
4.945AspGlu: 4.945 ± 1.131
1.648AspPhe: 1.648 ± 0.962
3.297AspGly: 3.297 ± 0.725
2.747AspHis: 2.747 ± 1.603
2.747AspIle: 2.747 ± 0.697
4.396AspLys: 4.396 ± 2.564
5.495AspLeu: 5.495 ± 1.825
0.0AspMet: 0.0 ± 0.0
1.099AspAsn: 1.099 ± 0.513
3.297AspPro: 3.297 ± 0.985
2.198AspGln: 2.198 ± 1.282
3.297AspArg: 3.297 ± 0.985
3.297AspSer: 3.297 ± 0.725
1.648AspThr: 1.648 ± 0.962
3.297AspVal: 3.297 ± 1.538
2.198AspTrp: 2.198 ± 0.454
1.099AspTyr: 1.099 ± 0.815
0.0AspXaa: 0.0 ± 0.0
Glu
4.945GluAla: 4.945 ± 0.06
1.099GluCys: 1.099 ± 0.815
4.945GluAsp: 4.945 ± 1.131
6.593GluGlu: 6.593 ± 1.61
0.549GluPhe: 0.549 ± 0.321
8.242GluGly: 8.242 ± 0.668
1.099GluHis: 1.099 ± 0.641
3.297GluIle: 3.297 ± 1.923
7.143GluLys: 7.143 ± 1.576
6.593GluLeu: 6.593 ± 0.841
2.198GluMet: 2.198 ± 0.454
3.297GluAsn: 3.297 ± 0.725
2.198GluPro: 2.198 ± 1.025
2.198GluGln: 2.198 ± 1.282
3.297GluArg: 3.297 ± 1.3
1.648GluSer: 1.648 ± 0.783
4.945GluThr: 4.945 ± 1.203
6.593GluVal: 6.593 ± 1.361
1.099GluTrp: 1.099 ± 0.815
2.198GluTyr: 2.198 ± 0.454
0.0GluXaa: 0.0 ± 0.0
Phe
2.198PheAla: 2.198 ± 0.454
0.549PheCys: 0.549 ± 0.321
1.648PheAsp: 1.648 ± 0.962
2.198PheGlu: 2.198 ± 0.454
1.099PhePhe: 1.099 ± 0.641
2.747PheGly: 2.747 ± 1.061
0.549PheHis: 0.549 ± 0.321
1.099PheIle: 1.099 ± 0.513
4.396PheLys: 4.396 ± 0.907
5.495PheLeu: 5.495 ± 1.274
0.0PheMet: 0.0 ± 0.0
0.549PheAsn: 0.549 ± 0.774
1.648PhePro: 1.648 ± 1.752
1.648PheGln: 1.648 ± 0.962
0.549PheArg: 0.549 ± 0.321
3.846PheSer: 3.846 ± 0.756
1.099PheThr: 1.099 ± 0.641
3.297PheVal: 3.297 ± 2.0
1.648PheTrp: 1.648 ± 0.363
1.648PheTyr: 1.648 ± 0.962
0.0PheXaa: 0.0 ± 0.0
Gly
7.692GlyAla: 7.692 ± 1.512
0.0GlyCys: 0.0 ± 0.0
3.297GlyAsp: 3.297 ± 0.985
4.396GlyGlu: 4.396 ± 1.171
3.846GlyPhe: 3.846 ± 0.653
5.495GlyGly: 5.495 ± 1.014
1.099GlyHis: 1.099 ± 0.815
0.549GlyIle: 0.549 ± 0.321
2.747GlyLys: 2.747 ± 0.507
10.989GlyLeu: 10.989 ± 1.136
1.099GlyMet: 1.099 ± 0.513
4.396GlyAsn: 4.396 ± 1.215
3.297GlyPro: 3.297 ± 0.42
2.747GlyGln: 2.747 ± 0.507
3.297GlyArg: 3.297 ± 2.446
4.396GlySer: 4.396 ± 2.434
6.044GlyThr: 6.044 ± 2.346
4.396GlyVal: 4.396 ± 1.599
0.549GlyTrp: 0.549 ± 0.321
1.648GlyTyr: 1.648 ± 1.017
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.549HisCys: 0.549 ± 0.321
0.549HisAsp: 0.549 ± 0.321
2.747HisGlu: 2.747 ± 1.603
1.648HisPhe: 1.648 ± 0.962
3.297HisGly: 3.297 ± 1.923
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.198HisLys: 2.198 ± 1.631
2.747HisLeu: 2.747 ± 1.566
0.549HisMet: 0.549 ± 0.774
1.099HisAsn: 1.099 ± 0.641
1.099HisPro: 1.099 ± 0.641
1.099HisGln: 1.099 ± 0.513
0.549HisArg: 0.549 ± 0.321
1.648HisSer: 1.648 ± 0.962
0.0HisThr: 0.0 ± 0.0
1.648HisVal: 1.648 ± 0.962
0.549HisTrp: 0.549 ± 0.96
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.648IleAla: 1.648 ± 0.363
0.0IleCys: 0.0 ± 0.0
1.648IleAsp: 1.648 ± 0.962
2.747IleGlu: 2.747 ± 0.828
0.549IlePhe: 0.549 ± 0.774
0.549IleGly: 0.549 ± 0.321
0.549IleHis: 0.549 ± 0.321
1.099IleIle: 1.099 ± 0.641
3.846IleLys: 3.846 ± 1.329
2.747IleLeu: 2.747 ± 1.061
1.099IleMet: 1.099 ± 0.591
0.549IleAsn: 0.549 ± 0.774
1.648IlePro: 1.648 ± 0.363
1.099IleGln: 1.099 ± 0.641
1.648IleArg: 1.648 ± 1.017
2.198IleSer: 2.198 ± 1.025
1.648IleThr: 1.648 ± 0.783
2.198IleVal: 2.198 ± 1.282
1.099IleTrp: 1.099 ± 0.513
0.549IleTyr: 0.549 ± 0.321
0.0IleXaa: 0.0 ± 0.0
Lys
6.044LysAla: 6.044 ± 1.523
1.648LysCys: 1.648 ± 0.962
3.297LysAsp: 3.297 ± 0.725
7.143LysGlu: 7.143 ± 1.84
1.648LysPhe: 1.648 ± 0.962
5.495LysGly: 5.495 ± 1.274
1.648LysHis: 1.648 ± 0.962
1.648LysIle: 1.648 ± 0.783
6.044LysLys: 6.044 ± 1.676
8.242LysLeu: 8.242 ± 0.956
0.549LysMet: 0.549 ± 0.321
3.297LysAsn: 3.297 ± 0.985
5.495LysPro: 5.495 ± 1.096
3.846LysGln: 3.846 ± 0.756
4.945LysArg: 4.945 ± 1.059
2.747LysSer: 2.747 ± 0.697
5.495LysThr: 5.495 ± 2.762
5.495LysVal: 5.495 ± 1.393
1.099LysTrp: 1.099 ± 0.641
3.297LysTyr: 3.297 ± 2.547
0.0LysXaa: 0.0 ± 0.0
Leu
6.593LeuAla: 6.593 ± 2.958
2.747LeuCys: 2.747 ± 1.293
4.945LeuAsp: 4.945 ± 2.885
6.593LeuGlu: 6.593 ± 2.6
4.945LeuPhe: 4.945 ± 0.06
6.593LeuGly: 6.593 ± 4.556
3.297LeuHis: 3.297 ± 2.446
2.198LeuIle: 2.198 ± 0.876
7.692LeuLys: 7.692 ± 1.626
10.989LeuLeu: 10.989 ± 5.183
0.549LeuMet: 0.549 ± 1.114
4.945LeuAsn: 4.945 ± 1.203
4.396LeuPro: 4.396 ± 0.335
4.396LeuGln: 4.396 ± 0.335
8.791LeuArg: 8.791 ± 1.367
8.791LeuSer: 8.791 ± 2.645
4.945LeuThr: 4.945 ± 1.081
7.692LeuVal: 7.692 ± 1.512
1.648LeuTrp: 1.648 ± 0.962
2.198LeuTyr: 2.198 ± 1.613
0.0LeuXaa: 0.0 ± 0.0
Met
1.099MetAla: 1.099 ± 0.513
1.099MetCys: 1.099 ± 1.549
0.549MetAsp: 0.549 ± 0.321
1.648MetGlu: 1.648 ± 1.017
0.549MetPhe: 0.549 ± 0.321
0.0MetGly: 0.0 ± 0.0
0.549MetHis: 0.549 ± 0.321
0.0MetIle: 0.0 ± 0.0
0.549MetLys: 0.549 ± 0.321
1.099MetLeu: 1.099 ± 0.641
0.0MetMet: 0.0 ± 0.0
0.549MetAsn: 0.549 ± 0.321
0.549MetPro: 0.549 ± 0.321
0.549MetGln: 0.549 ± 0.96
0.549MetArg: 0.549 ± 0.321
1.099MetSer: 1.099 ± 1.316
2.198MetThr: 2.198 ± 1.613
0.549MetVal: 0.549 ± 0.96
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.747AsnAla: 2.747 ± 1.78
0.549AsnCys: 0.549 ± 0.96
2.198AsnAsp: 2.198 ± 0.454
2.747AsnGlu: 2.747 ± 0.828
2.198AsnPhe: 2.198 ± 1.025
2.198AsnGly: 2.198 ± 1.025
0.0AsnHis: 0.0 ± 0.0
1.099AsnIle: 1.099 ± 0.513
2.198AsnLys: 2.198 ± 1.282
4.945AsnLeu: 4.945 ± 2.149
1.099AsnMet: 1.099 ± 0.815
2.198AsnAsn: 2.198 ± 2.045
3.297AsnPro: 3.297 ± 1.3
1.099AsnGln: 1.099 ± 0.513
1.099AsnArg: 1.099 ± 1.316
1.648AsnSer: 1.648 ± 0.363
2.747AsnThr: 2.747 ± 0.507
2.198AsnVal: 2.198 ± 0.876
0.549AsnTrp: 0.549 ± 0.321
0.549AsnTyr: 0.549 ± 0.321
0.0AsnXaa: 0.0 ± 0.0
Pro
1.099ProAla: 1.099 ± 0.641
0.549ProCys: 0.549 ± 0.774
1.648ProAsp: 1.648 ± 0.363
5.495ProGlu: 5.495 ± 1.382
2.198ProPhe: 2.198 ± 0.454
3.846ProGly: 3.846 ± 2.427
0.0ProHis: 0.0 ± 0.0
2.198ProIle: 2.198 ± 1.025
2.747ProLys: 2.747 ± 0.697
6.593ProLeu: 6.593 ± 2.84
0.549ProMet: 0.549 ± 0.601
2.747ProAsn: 2.747 ± 0.507
2.747ProPro: 2.747 ± 1.061
2.747ProGln: 2.747 ± 1.78
3.297ProArg: 3.297 ± 1.538
2.198ProSer: 2.198 ± 1.613
4.396ProThr: 4.396 ± 1.474
5.495ProVal: 5.495 ± 1.382
0.549ProTrp: 0.549 ± 0.321
2.747ProTyr: 2.747 ± 0.697
0.0ProXaa: 0.0 ± 0.0
Gln
2.198GlnAla: 2.198 ± 0.454
0.0GlnCys: 0.0 ± 0.0
2.747GlnAsp: 2.747 ± 0.507
1.648GlnGlu: 1.648 ± 0.363
0.549GlnPhe: 0.549 ± 0.96
2.747GlnGly: 2.747 ± 1.061
2.198GlnHis: 2.198 ± 0.454
0.549GlnIle: 0.549 ± 0.774
4.396GlnLys: 4.396 ± 0.795
3.297GlnLeu: 3.297 ± 1.538
1.099GlnMet: 1.099 ± 0.815
0.549GlnAsn: 0.549 ± 0.321
2.747GlnPro: 2.747 ± 1.603
1.648GlnGln: 1.648 ± 1.017
3.846GlnArg: 3.846 ± 1.329
1.648GlnSer: 1.648 ± 0.363
2.198GlnThr: 2.198 ± 0.876
3.846GlnVal: 3.846 ± 0.55
1.648GlnTrp: 1.648 ± 0.962
1.099GlnTyr: 1.099 ± 0.513
0.0GlnXaa: 0.0 ± 0.0
Arg
3.297ArgAla: 3.297 ± 0.725
0.0ArgCys: 0.0 ± 0.0
5.495ArgAsp: 5.495 ± 2.229
3.846ArgGlu: 3.846 ± 1.309
2.747ArgPhe: 2.747 ± 1.673
3.846ArgGly: 3.846 ± 2.29
1.648ArgHis: 1.648 ± 0.962
2.198ArgIle: 2.198 ± 0.454
6.593ArgLys: 6.593 ± 0.306
6.044ArgLeu: 6.044 ± 4.186
0.549ArgMet: 0.549 ± 0.774
2.198ArgAsn: 2.198 ± 0.454
1.648ArgPro: 1.648 ± 0.783
3.297ArgGln: 3.297 ± 0.985
4.396ArgArg: 4.396 ± 1.215
3.846ArgSer: 3.846 ± 2.427
1.648ArgThr: 1.648 ± 0.962
6.044ArgVal: 6.044 ± 3.526
1.648ArgTrp: 1.648 ± 2.17
0.549ArgTyr: 0.549 ± 0.321
0.0ArgXaa: 0.0 ± 0.0
Ser
4.396SerAla: 4.396 ± 1.171
0.549SerCys: 0.549 ± 0.321
2.198SerAsp: 2.198 ± 1.025
3.846SerGlu: 3.846 ± 1.569
1.099SerPhe: 1.099 ± 0.641
5.495SerGly: 5.495 ± 1.393
1.099SerHis: 1.099 ± 0.815
2.198SerIle: 2.198 ± 0.454
6.044SerLys: 6.044 ± 2.596
6.044SerLeu: 6.044 ± 1.974
0.549SerMet: 0.549 ± 0.96
3.846SerAsn: 3.846 ± 0.653
3.297SerPro: 3.297 ± 2.0
2.198SerGln: 2.198 ± 0.454
3.846SerArg: 3.846 ± 0.756
4.396SerSer: 4.396 ± 2.05
2.747SerThr: 2.747 ± 0.828
6.044SerVal: 6.044 ± 1.523
1.648SerTrp: 1.648 ± 0.783
2.198SerTyr: 2.198 ± 0.454
0.0SerXaa: 0.0 ± 0.0
Thr
3.846ThrAla: 3.846 ± 0.756
0.549ThrCys: 0.549 ± 0.321
5.495ThrAsp: 5.495 ± 1.648
1.099ThrGlu: 1.099 ± 1.316
4.396ThrPhe: 4.396 ± 1.599
2.747ThrGly: 2.747 ± 0.828
1.099ThrHis: 1.099 ± 0.641
2.198ThrIle: 2.198 ± 1.025
2.747ThrLys: 2.747 ± 1.603
3.846ThrLeu: 3.846 ± 0.55
0.0ThrMet: 0.0 ± 0.0
2.747ThrAsn: 2.747 ± 1.78
2.747ThrPro: 2.747 ± 2.848
3.846ThrGln: 3.846 ± 1.63
2.747ThrArg: 2.747 ± 1.061
6.593ThrSer: 6.593 ± 2.305
3.846ThrThr: 3.846 ± 1.569
2.747ThrVal: 2.747 ± 0.828
0.549ThrTrp: 0.549 ± 0.321
1.648ThrTyr: 1.648 ± 0.783
0.0ThrXaa: 0.0 ± 0.0
Val
4.945ValAla: 4.945 ± 0.06
3.846ValCys: 3.846 ± 0.756
4.945ValAsp: 4.945 ± 1.131
7.692ValGlu: 7.692 ± 2.578
3.297ValPhe: 3.297 ± 0.42
4.396ValGly: 4.396 ± 1.171
1.099ValHis: 1.099 ± 0.641
1.099ValIle: 1.099 ± 1.549
5.495ValLys: 5.495 ± 1.096
7.692ValLeu: 7.692 ± 0.782
0.549ValMet: 0.549 ± 0.96
1.099ValAsn: 1.099 ± 0.641
7.692ValPro: 7.692 ± 0.782
3.297ValGln: 3.297 ± 1.566
3.846ValArg: 3.846 ± 2.244
5.495ValSer: 5.495 ± 2.229
3.846ValThr: 3.846 ± 1.289
4.396ValVal: 4.396 ± 1.37
0.549ValTrp: 0.549 ± 0.321
1.648ValTyr: 1.648 ± 0.962
0.0ValXaa: 0.0 ± 0.0
Trp
0.549TrpAla: 0.549 ± 0.321
0.549TrpCys: 0.549 ± 0.321
0.0TrpAsp: 0.0 ± 0.0
1.099TrpGlu: 1.099 ± 0.513
0.0TrpPhe: 0.0 ± 0.0
1.099TrpGly: 1.099 ± 0.641
0.0TrpHis: 0.0 ± 0.0
1.099TrpIle: 1.099 ± 0.641
2.198TrpLys: 2.198 ± 0.876
4.945TrpLeu: 4.945 ± 3.181
0.549TrpMet: 0.549 ± 0.321
0.549TrpAsn: 0.549 ± 0.321
0.0TrpPro: 0.0 ± 0.0
1.099TrpGln: 1.099 ± 0.513
2.198TrpArg: 2.198 ± 1.282
1.648TrpSer: 1.648 ± 2.323
0.0TrpThr: 0.0 ± 0.0
2.198TrpVal: 2.198 ± 1.282
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.099TyrAla: 1.099 ± 0.513
1.099TyrCys: 1.099 ± 0.513
0.549TyrAsp: 0.549 ± 0.774
1.099TyrGlu: 1.099 ± 0.513
1.099TyrPhe: 1.099 ± 0.641
1.648TyrGly: 1.648 ± 0.363
1.648TyrHis: 1.648 ± 0.962
1.648TyrIle: 1.648 ± 0.783
0.0TyrLys: 0.0 ± 0.0
2.198TyrLeu: 2.198 ± 0.876
0.549TyrMet: 0.549 ± 0.321
1.099TyrAsn: 1.099 ± 0.815
0.549TyrPro: 0.549 ± 0.321
1.099TyrGln: 1.099 ± 0.513
2.198TyrArg: 2.198 ± 0.454
1.099TyrSer: 1.099 ± 0.641
2.747TyrThr: 2.747 ± 0.828
2.198TyrVal: 2.198 ± 1.613
1.099TyrTrp: 1.099 ± 0.641
0.549TyrTyr: 0.549 ± 0.774
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1821 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski