Amino acid dipepetide frequency for Tautonia sociabilis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.124AlaAla: 14.124 ± 0.129	1.035AlaCys: 1.035 ± 0.025	7.176AlaAsp: 7.176 ± 0.07	8.665AlaGlu: 8.665 ± 0.086	4.018AlaPhe: 4.018 ± 0.052	10.259AlaGly: 10.259 ± 0.094	1.703AlaHis: 1.703 ± 0.03	5.785AlaIle: 5.785 ± 0.058	2.251AlaLys: 2.251 ± 0.041	12.865AlaLeu: 12.865 ± 0.126	2.654AlaMet: 2.654 ± 0.039	2.067AlaAsn: 2.067 ± 0.047	6.519AlaPro: 6.519 ± 0.09	2.681AlaGln: 2.681 ± 0.041	9.811AlaArg: 9.811 ± 0.1	7.266AlaSer: 7.266 ± 0.077	5.079AlaThr: 5.079 ± 0.054	8.706AlaVal: 8.706 ± 0.078	1.505AlaTrp: 1.505 ± 0.032	1.963AlaTyr: 1.963 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	0.724CysAla: 0.724 ± 0.025	0.196CysCys: 0.196 ± 0.015	0.517CysAsp: 0.517 ± 0.017	0.447CysGlu: 0.447 ± 0.015	0.295CysPhe: 0.295 ± 0.012	0.862CysGly: 0.862 ± 0.024	0.373CysHis: 0.373 ± 0.021	0.271CysIle: 0.271 ± 0.014	0.162CysLys: 0.162 ± 0.01	0.968CysLeu: 0.968 ± 0.024	0.124CysMet: 0.124 ± 0.008	0.19CysAsn: 0.19 ± 0.012	0.672CysPro: 0.672 ± 0.02	0.249CysGln: 0.249 ± 0.01	0.929CysArg: 0.929 ± 0.027	0.61CysSer: 0.61 ± 0.018	0.357CysThr: 0.357 ± 0.016	0.568CysVal: 0.568 ± 0.017	0.202CysTrp: 0.202 ± 0.011	0.239CysTyr: 0.239 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.748AspAla: 6.748 ± 0.064	0.468AspCys: 0.468 ± 0.018	4.121AspAsp: 4.121 ± 0.058	4.087AspGlu: 4.087 ± 0.055	1.823AspPhe: 1.823 ± 0.032	6.266AspGly: 6.266 ± 0.087	1.405AspHis: 1.405 ± 0.032	1.578AspIle: 1.578 ± 0.031	0.723AspLys: 0.723 ± 0.022	7.095AspLeu: 7.095 ± 0.075	0.646AspMet: 0.646 ± 0.019	0.889AspAsn: 0.889 ± 0.028	6.06AspPro: 6.06 ± 0.072	1.737AspGln: 1.737 ± 0.036	7.849AspArg: 7.849 ± 0.079	2.723AspSer: 2.723 ± 0.036	1.946AspThr: 1.946 ± 0.038	3.79AspVal: 3.79 ± 0.047	1.024AspTrp: 1.024 ± 0.025	1.293AspTyr: 1.293 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	9.208GluAla: 9.208 ± 0.082	0.387GluCys: 0.387 ± 0.016	3.122GluAsp: 3.122 ± 0.049	4.181GluGlu: 4.181 ± 0.058	1.814GluPhe: 1.814 ± 0.032	5.519GluGly: 5.519 ± 0.059	1.507GluHis: 1.507 ± 0.034	2.651GluIle: 2.651 ± 0.039	1.331GluLys: 1.331 ± 0.036	6.663GluLeu: 6.663 ± 0.068	1.027GluMet: 1.027 ± 0.023	1.154GluAsn: 1.154 ± 0.028	4.65GluPro: 4.65 ± 0.052	2.304GluGln: 2.304 ± 0.041	5.447GluArg: 5.447 ± 0.068	2.977GluSer: 2.977 ± 0.042	2.833GluThr: 2.833 ± 0.04	4.922GluVal: 4.922 ± 0.058	0.695GluTrp: 0.695 ± 0.022	1.093GluTyr: 1.093 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.565PheAla: 3.565 ± 0.044	0.302PheCys: 0.302 ± 0.015	2.672PheAsp: 2.672 ± 0.042	2.371PheGlu: 2.371 ± 0.04	1.107PhePhe: 1.107 ± 0.026	3.448PheGly: 3.448 ± 0.047	0.668PheHis: 0.668 ± 0.02	1.039PheIle: 1.039 ± 0.026	0.551PheLys: 0.551 ± 0.018	3.554PheLeu: 3.554 ± 0.051	0.43PheMet: 0.43 ± 0.015	0.774PheAsn: 0.774 ± 0.021	1.829PhePro: 1.829 ± 0.033	0.878PheGln: 0.878 ± 0.023	2.743PheArg: 2.743 ± 0.034	1.966PheSer: 1.966 ± 0.034	1.361PheThr: 1.361 ± 0.036	2.471PheVal: 2.471 ± 0.038	0.494PheTrp: 0.494 ± 0.018	0.725PheTyr: 0.725 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	8.566GlyAla: 8.566 ± 0.088	0.906GlyCys: 0.906 ± 0.025	5.246GlyAsp: 5.246 ± 0.074	5.258GlyGlu: 5.258 ± 0.063	3.172GlyPhe: 3.172 ± 0.046	8.423GlyGly: 8.423 ± 0.107	1.856GlyHis: 1.856 ± 0.034	3.768GlyIle: 3.768 ± 0.045	2.29GlyLys: 2.29 ± 0.04	9.926GlyLeu: 9.926 ± 0.088	2.046GlyMet: 2.046 ± 0.046	2.013GlyAsn: 2.013 ± 0.105	6.534GlyPro: 6.534 ± 0.077	2.758GlyGln: 2.758 ± 0.045	8.842GlyArg: 8.842 ± 0.081	5.66GlySer: 5.66 ± 0.08	4.739GlyThr: 4.739 ± 0.061	6.206GlyVal: 6.206 ± 0.081	1.536GlyTrp: 1.536 ± 0.031	1.947GlyTyr: 1.947 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	1.879HisAla: 1.879 ± 0.034	0.251HisCys: 0.251 ± 0.011	1.139HisAsp: 1.139 ± 0.027	1.052HisGlu: 1.052 ± 0.024	0.695HisPhe: 0.695 ± 0.02	1.739HisGly: 1.739 ± 0.034	0.581HisHis: 0.581 ± 0.018	0.6HisIle: 0.6 ± 0.017	0.322HisLys: 0.322 ± 0.014	2.21HisLeu: 2.21 ± 0.041	0.262HisMet: 0.262 ± 0.012	0.425HisAsn: 0.425 ± 0.016	1.746HisPro: 1.746 ± 0.037	0.528HisGln: 0.528 ± 0.017	2.022HisArg: 2.022 ± 0.037	0.895HisSer: 0.895 ± 0.022	0.697HisThr: 0.697 ± 0.021	1.324HisVal: 1.324 ± 0.027	0.4HisTrp: 0.4 ± 0.016	0.491HisTyr: 0.491 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	5.713IleAla: 5.713 ± 0.06	0.381IleCys: 0.381 ± 0.016	3.502IleAsp: 3.502 ± 0.045	3.179IleGlu: 3.179 ± 0.047	1.121IlePhe: 1.121 ± 0.028	4.432IleGly: 4.432 ± 0.059	0.778IleHis: 0.778 ± 0.021	1.365IleIle: 1.365 ± 0.033	0.857IleLys: 0.857 ± 0.025	3.904IleLeu: 3.904 ± 0.047	0.441IleMet: 0.441 ± 0.019	1.022IleAsn: 1.022 ± 0.03	2.626IlePro: 2.626 ± 0.037	1.033IleGln: 1.033 ± 0.024	3.988IleArg: 3.988 ± 0.045	2.081IleSer: 2.081 ± 0.039	1.901IleThr: 1.901 ± 0.041	3.36IleVal: 3.36 ± 0.04	0.46IleTrp: 0.46 ± 0.015	0.827IleTyr: 0.827 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	2.652LysAla: 2.652 ± 0.041	0.135LysCys: 0.135 ± 0.01	1.169LysAsp: 1.169 ± 0.026	1.171LysGlu: 1.171 ± 0.03	0.552LysPhe: 0.552 ± 0.02	1.698LysGly: 1.698 ± 0.033	0.397LysHis: 0.397 ± 0.015	0.954LysIle: 0.954 ± 0.026	0.677LysLys: 0.677 ± 0.023	1.924LysLeu: 1.924 ± 0.036	0.354LysMet: 0.354 ± 0.013	0.468LysAsn: 0.468 ± 0.016	1.405LysPro: 1.405 ± 0.03	0.662LysGln: 0.662 ± 0.024	1.6LysArg: 1.6 ± 0.032	0.95LysSer: 0.95 ± 0.026	1.199LysThr: 1.199 ± 0.028	1.657LysVal: 1.657 ± 0.038	0.219LysTrp: 0.219 ± 0.011	0.487LysTyr: 0.487 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	14.434LeuAla: 14.434 ± 0.112	0.984LeuCys: 0.984 ± 0.028	7.391LeuAsp: 7.391 ± 0.074	6.164LeuGlu: 6.164 ± 0.064	3.196LeuPhe: 3.196 ± 0.044	9.955LeuGly: 9.955 ± 0.077	1.774LeuHis: 1.774 ± 0.038	4.643LeuIle: 4.643 ± 0.057	2.349LeuLys: 2.349 ± 0.04	11.307LeuLeu: 11.307 ± 0.11	1.737LeuMet: 1.737 ± 0.031	2.05LeuAsn: 2.05 ± 0.037	6.73LeuPro: 6.73 ± 0.059	2.333LeuGln: 2.333 ± 0.037	8.726LeuArg: 8.726 ± 0.087	5.924LeuSer: 5.924 ± 0.065	4.849LeuThr: 4.849 ± 0.06	8.062LeuVal: 8.062 ± 0.068	1.318LeuTrp: 1.318 ± 0.028	1.995LeuTyr: 1.995 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.42MetAla: 2.42 ± 0.033	0.106MetCys: 0.106 ± 0.009	0.848MetAsp: 0.848 ± 0.021	0.884MetGlu: 0.884 ± 0.023	0.446MetPhe: 0.446 ± 0.017	1.409MetGly: 1.409 ± 0.039	0.33MetHis: 0.33 ± 0.013	0.963MetIle: 0.963 ± 0.022	0.461MetLys: 0.461 ± 0.017	1.886MetLeu: 1.886 ± 0.04	0.409MetMet: 0.409 ± 0.021	0.505MetAsn: 0.505 ± 0.015	1.369MetPro: 1.369 ± 0.027	0.432MetGln: 0.432 ± 0.014	1.353MetArg: 1.353 ± 0.027	1.071MetSer: 1.071 ± 0.026	1.207MetThr: 1.207 ± 0.023	1.199MetVal: 1.199 ± 0.026	0.138MetTrp: 0.138 ± 0.009	0.274MetTyr: 0.274 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.248AsnAla: 2.248 ± 0.047	0.214AsnCys: 0.214 ± 0.011	1.196AsnAsp: 1.196 ± 0.034	0.935AsnGlu: 0.935 ± 0.021	0.715AsnPhe: 0.715 ± 0.024	1.868AsnGly: 1.868 ± 0.045	0.481AsnHis: 0.481 ± 0.017	0.769AsnIle: 0.769 ± 0.02	0.33AsnLys: 0.33 ± 0.014	2.303AsnLeu: 2.303 ± 0.051	0.298AsnMet: 0.298 ± 0.012	0.561AsnAsn: 0.561 ± 0.023	1.759AsnPro: 1.759 ± 0.035	0.653AsnGln: 0.653 ± 0.02	1.89AsnArg: 1.89 ± 0.036	0.952AsnSer: 0.952 ± 0.032	0.98AsnThr: 0.98 ± 0.036	1.535AsnVal: 1.535 ± 0.041	0.31AsnTrp: 0.31 ± 0.012	0.542AsnTyr: 0.542 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.743ProAla: 7.743 ± 0.089	0.436ProCys: 0.436 ± 0.017	5.482ProAsp: 5.482 ± 0.068	5.897ProGlu: 5.897 ± 0.059	2.106ProPhe: 2.106 ± 0.037	7.476ProGly: 7.476 ± 0.08	1.11ProHis: 1.11 ± 0.023	3.358ProIle: 3.358 ± 0.048	1.403ProLys: 1.403 ± 0.033	5.537ProLeu: 5.537 ± 0.057	1.46ProMet: 1.46 ± 0.031	1.553ProAsn: 1.553 ± 0.037	5.525ProPro: 5.525 ± 0.083	1.369ProGln: 1.369 ± 0.031	4.955ProArg: 4.955 ± 0.052	4.837ProSer: 4.837 ± 0.068	3.532ProThr: 3.532 ± 0.05	4.669ProVal: 4.669 ± 0.054	0.95ProTrp: 0.95 ± 0.024	1.189ProTyr: 1.189 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.514GlnAla: 3.514 ± 0.05	0.233GlnCys: 0.233 ± 0.012	1.305GlnAsp: 1.305 ± 0.029	1.534GlnGlu: 1.534 ± 0.032	0.946GlnPhe: 0.946 ± 0.022	2.314GlnGly: 2.314 ± 0.039	0.504GlnHis: 0.504 ± 0.018	1.305GlnIle: 1.305 ± 0.03	0.615GlnLys: 0.615 ± 0.02	2.627GlnLeu: 2.627 ± 0.039	0.492GlnMet: 0.492 ± 0.017	0.55GlnAsn: 0.55 ± 0.018	1.608GlnPro: 1.608 ± 0.033	0.925GlnGln: 0.925 ± 0.028	2.063GlnArg: 2.063 ± 0.034	1.263GlnSer: 1.263 ± 0.029	1.296GlnThr: 1.296 ± 0.024	2.192GlnVal: 2.192 ± 0.032	0.362GlnTrp: 0.362 ± 0.015	0.567GlnTyr: 0.567 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	9.118ArgAla: 9.118 ± 0.09	0.813ArgCys: 0.813 ± 0.023	4.986ArgAsp: 4.986 ± 0.061	5.322ArgGlu: 5.322 ± 0.056	3.589ArgPhe: 3.589 ± 0.044	6.403ArgGly: 6.403 ± 0.06	1.813ArgHis: 1.813 ± 0.038	4.189ArgIle: 4.189 ± 0.058	1.829ArgLys: 1.829 ± 0.032	10.51ArgLeu: 10.51 ± 0.099	1.797ArgMet: 1.797 ± 0.03	1.716ArgAsn: 1.716 ± 0.033	6.508ArgPro: 6.508 ± 0.072	2.478ArgGln: 2.478 ± 0.041	9.214ArgArg: 9.214 ± 0.1	5.813ArgSer: 5.813 ± 0.057	3.792ArgThr: 3.792 ± 0.045	6.088ArgVal: 6.088 ± 0.067	1.645ArgTrp: 1.645 ± 0.032	1.933ArgTyr: 1.933 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.337SerAla: 6.337 ± 0.077	0.636SerCys: 0.636 ± 0.022	3.094SerAsp: 3.094 ± 0.045	2.94SerGlu: 2.94 ± 0.042	1.895SerPhe: 1.895 ± 0.036	6.178SerGly: 6.178 ± 0.093	1.02SerHis: 1.02 ± 0.026	2.368SerIle: 2.368 ± 0.033	1.119SerLys: 1.119 ± 0.025	5.403SerLeu: 5.403 ± 0.055	0.996SerMet: 0.996 ± 0.026	1.187SerAsn: 1.187 ± 0.031	4.866SerPro: 4.866 ± 0.066	1.438SerGln: 1.438 ± 0.029	5.286SerArg: 5.286 ± 0.053	3.826SerSer: 3.826 ± 0.069	2.612SerThr: 2.612 ± 0.041	3.659SerVal: 3.659 ± 0.046	1.243SerTrp: 1.243 ± 0.026	1.444SerTyr: 1.444 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	4.898ThrAla: 4.898 ± 0.057	0.387ThrCys: 0.387 ± 0.014	2.555ThrAsp: 2.555 ± 0.042	2.292ThrGlu: 2.292 ± 0.041	1.817ThrPhe: 1.817 ± 0.033	4.353ThrGly: 4.353 ± 0.056	0.788ThrHis: 0.788 ± 0.021	2.84ThrIle: 2.84 ± 0.044	0.902ThrLys: 0.902 ± 0.023	5.211ThrLeu: 5.211 ± 0.058	0.837ThrMet: 0.837 ± 0.025	1.049ThrAsn: 1.049 ± 0.029	3.392ThrPro: 3.392 ± 0.052	0.954ThrGln: 0.954 ± 0.024	3.246ThrArg: 3.246 ± 0.041	2.436ThrSer: 2.436 ± 0.041	2.399ThrThr: 2.399 ± 0.042	3.707ThrVal: 3.707 ± 0.058	0.639ThrTrp: 0.639 ± 0.019	1.047ThrTyr: 1.047 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	8.789ValAla: 8.789 ± 0.076	0.684ValCys: 0.684 ± 0.026	4.523ValAsp: 4.523 ± 0.056	5.09ValGlu: 5.09 ± 0.059	2.291ValPhe: 2.291 ± 0.038	6.292ValGly: 6.292 ± 0.07	1.246ValHis: 1.246 ± 0.028	3.215ValIle: 3.215 ± 0.051	1.404ValLys: 1.404 ± 0.032	8.035ValLeu: 8.035 ± 0.075	1.112ValMet: 1.112 ± 0.026	1.497ValAsn: 1.497 ± 0.03	4.714ValPro: 4.714 ± 0.062	1.679ValGln: 1.679 ± 0.027	6.027ValArg: 6.027 ± 0.066	4.32ValSer: 4.32 ± 0.051	3.279ValThr: 3.279 ± 0.048	6.685ValVal: 6.685 ± 0.076	0.82ValTrp: 0.82 ± 0.019	1.418ValTyr: 1.418 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.504TrpAla: 1.504 ± 0.03	0.151TrpCys: 0.151 ± 0.009	0.848TrpAsp: 0.848 ± 0.021	0.809TrpGlu: 0.809 ± 0.021	0.536TrpPhe: 0.536 ± 0.018	1.063TrpGly: 1.063 ± 0.023	0.342TrpHis: 0.342 ± 0.014	0.67TrpIle: 0.67 ± 0.02	0.331TrpLys: 0.331 ± 0.014	1.705TrpLeu: 1.705 ± 0.032	0.306TrpMet: 0.306 ± 0.015	0.343TrpAsn: 0.343 ± 0.014	0.942TrpPro: 0.942 ± 0.022	0.409TrpGln: 0.409 ± 0.016	1.291TrpArg: 1.291 ± 0.027	0.944TrpSer: 0.944 ± 0.024	0.802TrpThr: 0.802 ± 0.022	0.959TrpVal: 0.959 ± 0.026	0.287TrpTrp: 0.287 ± 0.013	0.338TrpTyr: 0.338 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.945TyrAla: 1.945 ± 0.034	0.248TyrCys: 0.248 ± 0.012	1.379TyrAsp: 1.379 ± 0.031	1.21TyrGlu: 1.21 ± 0.027	0.813TyrPhe: 0.813 ± 0.023	1.737TyrGly: 1.737 ± 0.034	0.582TyrHis: 0.582 ± 0.019	0.638TyrIle: 0.638 ± 0.019	0.422TyrLys: 0.422 ± 0.015	2.289TyrLeu: 2.289 ± 0.036	0.287TyrMet: 0.287 ± 0.012	0.526TyrAsn: 0.526 ± 0.017	1.133TyrPro: 1.133 ± 0.025	0.713TyrGln: 0.713 ± 0.019	2.274TyrArg: 2.274 ± 0.039	1.033TyrSer: 1.033 ± 0.023	0.891TyrThr: 0.891 ± 0.022	1.364TyrVal: 1.364 ± 0.03	0.332TyrTrp: 0.332 ± 0.015	0.615TyrTyr: 0.615 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4914 proteins (1862055 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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