Amino acid dipepetide frequency for Lacinutrix sp. (strain 5H-3-7-4)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.926AlaAla: 3.926 ± 0.074	0.517AlaCys: 0.517 ± 0.023	2.993AlaAsp: 2.993 ± 0.082	3.921AlaGlu: 3.921 ± 0.069	3.592AlaPhe: 3.592 ± 0.058	3.894AlaGly: 3.894 ± 0.076	1.042AlaHis: 1.042 ± 0.038	5.757AlaIle: 5.757 ± 0.085	5.248AlaLys: 5.248 ± 0.085	6.527AlaLeu: 6.527 ± 0.103	1.469AlaMet: 1.469 ± 0.047	4.015AlaAsn: 4.015 ± 0.068	1.833AlaPro: 1.833 ± 0.054	2.5AlaGln: 2.5 ± 0.061	1.756AlaArg: 1.756 ± 0.05	4.163AlaSer: 4.163 ± 0.066	4.017AlaThr: 4.017 ± 0.099	3.978AlaVal: 3.978 ± 0.073	0.562AlaTrp: 0.562 ± 0.028	2.43AlaTyr: 2.43 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.456CysAla: 0.456 ± 0.022	0.085CysCys: 0.085 ± 0.008	0.554CysAsp: 0.554 ± 0.054	0.525CysGlu: 0.525 ± 0.027	0.422CysPhe: 0.422 ± 0.021	0.617CysGly: 0.617 ± 0.035	0.16CysHis: 0.16 ± 0.014	0.63CysIle: 0.63 ± 0.025	0.531CysLys: 0.531 ± 0.023	0.628CysLeu: 0.628 ± 0.024	0.139CysMet: 0.139 ± 0.013	0.486CysAsn: 0.486 ± 0.024	0.329CysPro: 0.329 ± 0.025	0.186CysGln: 0.186 ± 0.015	0.15CysArg: 0.15 ± 0.011	0.575CysSer: 0.575 ± 0.037	0.407CysThr: 0.407 ± 0.022	0.447CysVal: 0.447 ± 0.026	0.072CysTrp: 0.072 ± 0.015	0.295CysTyr: 0.295 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.074AspAla: 4.074 ± 0.09	0.535AspCys: 0.535 ± 0.047	3.047AspAsp: 3.047 ± 0.068	3.58AspGlu: 3.58 ± 0.071	3.575AspPhe: 3.575 ± 0.064	3.738AspGly: 3.738 ± 0.134	0.766AspHis: 0.766 ± 0.028	4.504AspIle: 4.504 ± 0.068	3.972AspLys: 3.972 ± 0.078	5.072AspLeu: 5.072 ± 0.08	0.986AspMet: 0.986 ± 0.031	3.717AspAsn: 3.717 ± 0.071	1.603AspPro: 1.603 ± 0.1	1.284AspGln: 1.284 ± 0.043	1.616AspArg: 1.616 ± 0.04	3.277AspSer: 3.277 ± 0.059	3.143AspThr: 3.143 ± 0.074	3.794AspVal: 3.794 ± 0.074	0.67AspTrp: 0.67 ± 0.028	2.851AspTyr: 2.851 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	4.674GluAla: 4.674 ± 0.088	0.335GluCys: 0.335 ± 0.02	3.851GluAsp: 3.851 ± 0.072	4.48GluGlu: 4.48 ± 0.092	2.886GluPhe: 2.886 ± 0.051	3.235GluGly: 3.235 ± 0.067	1.148GluHis: 1.148 ± 0.039	5.417GluIle: 5.417 ± 0.076	5.601GluLys: 5.601 ± 0.095	5.77GluLeu: 5.77 ± 0.083	1.288GluMet: 1.288 ± 0.037	5.166GluAsn: 5.166 ± 0.093	1.577GluPro: 1.577 ± 0.051	2.292GluGln: 2.292 ± 0.054	2.292GluArg: 2.292 ± 0.062	3.342GluSer: 3.342 ± 0.058	4.363GluThr: 4.363 ± 0.075	4.055GluVal: 4.055 ± 0.078	0.52GluTrp: 0.52 ± 0.024	2.322GluTyr: 2.322 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	2.933PheAla: 2.933 ± 0.055	0.434PheCys: 0.434 ± 0.02	3.192PheAsp: 3.192 ± 0.063	3.27PheGlu: 3.27 ± 0.057	2.706PhePhe: 2.706 ± 0.07	3.563PheGly: 3.563 ± 0.062	0.759PheHis: 0.759 ± 0.029	4.056PheIle: 4.056 ± 0.073	4.493PheLys: 4.493 ± 0.093	4.525PheLeu: 4.525 ± 0.087	1.013PheMet: 1.013 ± 0.031	4.076PheAsn: 4.076 ± 0.069	1.534PhePro: 1.534 ± 0.039	1.47PheGln: 1.47 ± 0.042	1.422PheArg: 1.422 ± 0.041	4.08PheSer: 4.08 ± 0.075	3.422PheThr: 3.422 ± 0.081	2.901PheVal: 2.901 ± 0.052	0.516PheTrp: 0.516 ± 0.024	2.199PheTyr: 2.199 ± 0.054	0.0PheXaa: 0.0 ± 0.0
Gly	3.854GlyAla: 3.854 ± 0.08	0.562GlyCys: 0.562 ± 0.036	3.559GlyAsp: 3.559 ± 0.095	3.594GlyGlu: 3.594 ± 0.066	3.573GlyPhe: 3.573 ± 0.071	4.058GlyGly: 4.058 ± 0.083	1.035GlyHis: 1.035 ± 0.034	4.905GlyIle: 4.905 ± 0.076	4.62GlyLys: 4.62 ± 0.079	5.442GlyLeu: 5.442 ± 0.08	1.385GlyMet: 1.385 ± 0.044	3.76GlyAsn: 3.76 ± 0.087	1.229GlyPro: 1.229 ± 0.038	1.693GlyGln: 1.693 ± 0.047	1.836GlyArg: 1.836 ± 0.048	3.693GlySer: 3.693 ± 0.082	3.986GlyThr: 3.986 ± 0.114	4.092GlyVal: 4.092 ± 0.08	0.641GlyTrp: 0.641 ± 0.027	2.569GlyTyr: 2.569 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	0.888HisAla: 0.888 ± 0.032	0.173HisCys: 0.173 ± 0.014	0.848HisAsp: 0.848 ± 0.031	0.916HisGlu: 0.916 ± 0.034	1.127HisPhe: 1.127 ± 0.04	0.921HisGly: 0.921 ± 0.032	0.405HisHis: 0.405 ± 0.023	1.405HisIle: 1.405 ± 0.043	1.232HisLys: 1.232 ± 0.04	1.659HisLeu: 1.659 ± 0.046	0.298HisMet: 0.298 ± 0.016	1.024HisAsn: 1.024 ± 0.028	0.726HisPro: 0.726 ± 0.028	0.57HisGln: 0.57 ± 0.024	0.53HisArg: 0.53 ± 0.024	0.934HisSer: 0.934 ± 0.035	0.893HisThr: 0.893 ± 0.03	0.848HisVal: 0.848 ± 0.033	0.183HisTrp: 0.183 ± 0.011	0.784HisTyr: 0.784 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.682IleAla: 5.682 ± 0.086	0.597IleCys: 0.597 ± 0.028	5.066IleAsp: 5.066 ± 0.074	6.0IleGlu: 6.0 ± 0.083	3.544IlePhe: 3.544 ± 0.065	4.893IleGly: 4.893 ± 0.074	1.191IleHis: 1.191 ± 0.033	6.759IleIle: 6.759 ± 0.105	6.588IleLys: 6.588 ± 0.097	7.137IleLeu: 7.137 ± 0.118	1.336IleMet: 1.336 ± 0.037	5.616IleAsn: 5.616 ± 0.096	3.039IlePro: 3.039 ± 0.055	2.386IleGln: 2.386 ± 0.053	2.113IleArg: 2.113 ± 0.048	5.566IleSer: 5.566 ± 0.081	5.632IleThr: 5.632 ± 0.087	4.943IleVal: 4.943 ± 0.078	0.63IleTrp: 0.63 ± 0.026	2.803IleTyr: 2.803 ± 0.057	0.0IleXaa: 0.0 ± 0.0
Lys	5.565LysAla: 5.565 ± 0.095	0.351LysCys: 0.351 ± 0.02	4.586LysAsp: 4.586 ± 0.09	5.896LysGlu: 5.896 ± 0.111	3.031LysPhe: 3.031 ± 0.06	4.299LysGly: 4.299 ± 0.072	1.618LysHis: 1.618 ± 0.042	6.398LysIle: 6.398 ± 0.093	7.284LysLys: 7.284 ± 0.121	7.017LysLeu: 7.017 ± 0.101	1.973LysMet: 1.973 ± 0.051	6.058LysAsn: 6.058 ± 0.105	2.672LysPro: 2.672 ± 0.053	3.311LysGln: 3.311 ± 0.063	2.945LysArg: 2.945 ± 0.067	4.782LysSer: 4.782 ± 0.083	5.682LysThr: 5.682 ± 0.093	4.66LysVal: 4.66 ± 0.084	0.759LysTrp: 0.759 ± 0.034	3.208LysTyr: 3.208 ± 0.067	0.0LysXaa: 0.0 ± 0.0
Leu	5.602LeuAla: 5.602 ± 0.092	0.689LeuCys: 0.689 ± 0.026	5.216LeuAsp: 5.216 ± 0.086	6.192LeuGlu: 6.192 ± 0.093	4.746LeuPhe: 4.746 ± 0.09	5.353LeuGly: 5.353 ± 0.092	1.375LeuHis: 1.375 ± 0.041	7.116LeuIle: 7.116 ± 0.1	8.385LeuLys: 8.385 ± 0.119	8.206LeuLeu: 8.206 ± 0.13	1.878LeuMet: 1.878 ± 0.043	6.577LeuAsn: 6.577 ± 0.09	3.244LeuPro: 3.244 ± 0.057	3.125LeuGln: 3.125 ± 0.063	2.802LeuArg: 2.802 ± 0.054	6.317LeuSer: 6.317 ± 0.093	5.181LeuThr: 5.181 ± 0.076	5.149LeuVal: 5.149 ± 0.083	0.732LeuTrp: 0.732 ± 0.027	3.127LeuTyr: 3.127 ± 0.064	0.0LeuXaa: 0.0 ± 0.0
Met	1.539MetAla: 1.539 ± 0.044	0.123MetCys: 0.123 ± 0.011	0.956MetAsp: 0.956 ± 0.033	1.17MetGlu: 1.17 ± 0.037	0.84MetPhe: 0.84 ± 0.03	1.061MetGly: 1.061 ± 0.034	0.402MetHis: 0.402 ± 0.023	1.318MetIle: 1.318 ± 0.042	2.02MetLys: 2.02 ± 0.047	1.868MetLeu: 1.868 ± 0.043	0.477MetMet: 0.477 ± 0.022	1.152MetAsn: 1.152 ± 0.034	0.841MetPro: 0.841 ± 0.032	0.866MetGln: 0.866 ± 0.03	0.725MetArg: 0.725 ± 0.03	1.399MetSer: 1.399 ± 0.037	1.018MetThr: 1.018 ± 0.032	1.201MetVal: 1.201 ± 0.036	0.147MetTrp: 0.147 ± 0.013	0.668MetTyr: 0.668 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	4.47AsnAla: 4.47 ± 0.068	0.629AsnCys: 0.629 ± 0.036	3.596AsnAsp: 3.596 ± 0.081	4.166AsnGlu: 4.166 ± 0.074	3.41AsnPhe: 3.41 ± 0.071	4.391AsnGly: 4.391 ± 0.102	1.055AsnHis: 1.055 ± 0.033	5.748AsnIle: 5.748 ± 0.084	5.637AsnLys: 5.637 ± 0.105	6.126AsnLeu: 6.126 ± 0.1	1.263AsnMet: 1.263 ± 0.035	5.447AsnAsn: 5.447 ± 0.11	2.809AsnPro: 2.809 ± 0.067	2.405AsnGln: 2.405 ± 0.053	2.161AsnArg: 2.161 ± 0.052	4.15AsnSer: 4.15 ± 0.077	5.129AsnThr: 5.129 ± 0.11	3.959AsnVal: 3.959 ± 0.075	0.762AsnTrp: 0.762 ± 0.027	3.342AsnTyr: 3.342 ± 0.066	0.0AsnXaa: 0.0 ± 0.0
Pro	1.742ProAla: 1.742 ± 0.061	0.252ProCys: 0.252 ± 0.031	1.844ProAsp: 1.844 ± 0.049	2.706ProGlu: 2.706 ± 0.054	1.791ProPhe: 1.791 ± 0.037	1.754ProGly: 1.754 ± 0.054	0.524ProHis: 0.524 ± 0.023	2.622ProIle: 2.622 ± 0.062	2.649ProLys: 2.649 ± 0.057	2.776ProLeu: 2.776 ± 0.06	0.625ProMet: 0.625 ± 0.026	2.43ProAsn: 2.43 ± 0.062	0.674ProPro: 0.674 ± 0.03	1.091ProGln: 1.091 ± 0.038	0.76ProArg: 0.76 ± 0.027	1.872ProSer: 1.872 ± 0.049	2.038ProThr: 2.038 ± 0.068	2.146ProVal: 2.146 ± 0.053	0.259ProTrp: 0.259 ± 0.016	1.35ProTyr: 1.35 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.158GlnAla: 2.158 ± 0.057	0.195GlnCys: 0.195 ± 0.015	2.021GlnAsp: 2.021 ± 0.048	2.324GlnGlu: 2.324 ± 0.057	1.782GlnPhe: 1.782 ± 0.048	1.769GlnGly: 1.769 ± 0.049	0.592GlnHis: 0.592 ± 0.024	2.527GlnIle: 2.527 ± 0.044	2.534GlnLys: 2.534 ± 0.057	3.281GlnLeu: 3.281 ± 0.064	0.726GlnMet: 0.726 ± 0.027	2.208GlnAsn: 2.208 ± 0.052	1.051GlnPro: 1.051 ± 0.036	1.324GlnGln: 1.324 ± 0.052	1.045GlnArg: 1.045 ± 0.031	1.864GlnSer: 1.864 ± 0.043	2.255GlnThr: 2.255 ± 0.068	1.998GlnVal: 1.998 ± 0.046	0.33GlnTrp: 0.33 ± 0.018	1.338GlnTyr: 1.338 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	1.975ArgAla: 1.975 ± 0.048	0.179ArgCys: 0.179 ± 0.015	1.67ArgAsp: 1.67 ± 0.037	1.995ArgGlu: 1.995 ± 0.044	1.729ArgPhe: 1.729 ± 0.045	1.737ArgGly: 1.737 ± 0.043	0.514ArgHis: 0.514 ± 0.024	2.517ArgIle: 2.517 ± 0.056	2.469ArgLys: 2.469 ± 0.054	2.926ArgLeu: 2.926 ± 0.06	0.718ArgMet: 0.718 ± 0.028	1.904ArgAsn: 1.904 ± 0.049	0.924ArgPro: 0.924 ± 0.03	1.013ArgGln: 1.013 ± 0.032	1.16ArgArg: 1.16 ± 0.039	1.635ArgSer: 1.635 ± 0.045	1.701ArgThr: 1.701 ± 0.045	2.034ArgVal: 2.034 ± 0.045	0.304ArgTrp: 0.304 ± 0.02	1.335ArgTyr: 1.335 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.68SerAla: 3.68 ± 0.064	0.684SerCys: 0.684 ± 0.038	3.238SerAsp: 3.238 ± 0.068	3.403SerGlu: 3.403 ± 0.061	3.722SerPhe: 3.722 ± 0.063	4.319SerGly: 4.319 ± 0.078	1.045SerHis: 1.045 ± 0.034	5.361SerIle: 5.361 ± 0.075	5.442SerLys: 5.442 ± 0.086	5.666SerLeu: 5.666 ± 0.078	1.065SerMet: 1.065 ± 0.034	4.577SerAsn: 4.577 ± 0.073	1.926SerPro: 1.926 ± 0.044	2.304SerGln: 2.304 ± 0.048	1.969SerArg: 1.969 ± 0.044	3.986SerSer: 3.986 ± 0.078	3.844SerThr: 3.844 ± 0.089	3.727SerVal: 3.727 ± 0.067	0.616SerTrp: 0.616 ± 0.029	2.626SerTyr: 2.626 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.088ThrAla: 4.088 ± 0.11	0.424ThrCys: 0.424 ± 0.026	3.323ThrAsp: 3.323 ± 0.106	3.832ThrGlu: 3.832 ± 0.071	3.473ThrPhe: 3.473 ± 0.075	3.959ThrGly: 3.959 ± 0.091	0.963ThrHis: 0.963 ± 0.036	5.857ThrIle: 5.857 ± 0.098	4.671ThrLys: 4.671 ± 0.087	5.855ThrLeu: 5.855 ± 0.084	0.999ThrMet: 0.999 ± 0.037	4.444ThrAsn: 4.444 ± 0.107	2.479ThrPro: 2.479 ± 0.064	2.174ThrGln: 2.174 ± 0.059	1.637ThrArg: 1.637 ± 0.049	4.004ThrSer: 4.004 ± 0.087	4.231ThrThr: 4.231 ± 0.104	4.426ThrVal: 4.426 ± 0.107	0.581ThrTrp: 0.581 ± 0.03	2.542ThrTyr: 2.542 ± 0.062	0.0ThrXaa: 0.0 ± 0.0
Val	3.994ValAla: 3.994 ± 0.064	0.489ValCys: 0.489 ± 0.025	3.609ValAsp: 3.609 ± 0.08	4.049ValGlu: 4.049 ± 0.072	3.527ValPhe: 3.527 ± 0.07	3.653ValGly: 3.653 ± 0.081	0.841ValHis: 0.841 ± 0.03	4.995ValIle: 4.995 ± 0.074	4.511ValLys: 4.511 ± 0.082	5.823ValLeu: 5.823 ± 0.076	1.221ValMet: 1.221 ± 0.037	3.976ValAsn: 3.976 ± 0.07	1.944ValPro: 1.944 ± 0.052	1.534ValGln: 1.534 ± 0.041	1.765ValArg: 1.765 ± 0.046	4.377ValSer: 4.377 ± 0.075	3.95ValThr: 3.95 ± 0.099	4.146ValVal: 4.146 ± 0.083	0.533ValTrp: 0.533 ± 0.026	2.238ValTyr: 2.238 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.515TrpAla: 0.515 ± 0.024	0.089TrpCys: 0.089 ± 0.01	0.548TrpAsp: 0.548 ± 0.027	0.63TrpGlu: 0.63 ± 0.03	0.556TrpPhe: 0.556 ± 0.022	0.451TrpGly: 0.451 ± 0.024	0.202TrpHis: 0.202 ± 0.014	0.656TrpIle: 0.656 ± 0.029	0.704TrpLys: 0.704 ± 0.031	0.961TrpLeu: 0.961 ± 0.032	0.279TrpMet: 0.279 ± 0.018	0.663TrpAsn: 0.663 ± 0.023	0.191TrpPro: 0.191 ± 0.015	0.398TrpGln: 0.398 ± 0.023	0.334TrpArg: 0.334 ± 0.017	0.595TrpSer: 0.595 ± 0.026	0.549TrpThr: 0.549 ± 0.03	0.536TrpVal: 0.536 ± 0.023	0.124TrpTrp: 0.124 ± 0.011	0.407TrpTyr: 0.407 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.323TyrAla: 2.323 ± 0.049	0.352TyrCys: 0.352 ± 0.019	2.088TyrAsp: 2.088 ± 0.054	1.967TyrGlu: 1.967 ± 0.045	2.532TyrPhe: 2.532 ± 0.055	2.421TyrGly: 2.421 ± 0.057	0.727TyrHis: 0.727 ± 0.031	2.971TyrIle: 2.971 ± 0.06	3.505TyrLys: 3.505 ± 0.073	3.751TyrLeu: 3.751 ± 0.07	0.652TyrMet: 0.652 ± 0.026	3.357TyrAsn: 3.357 ± 0.069	1.275TyrPro: 1.275 ± 0.04	1.396TyrGln: 1.396 ± 0.042	1.42TyrArg: 1.42 ± 0.042	2.59TyrSer: 2.59 ± 0.055	2.523TyrThr: 2.523 ± 0.065	2.134TyrVal: 2.134 ± 0.042	0.448TyrTrp: 0.448 ± 0.022	1.835TyrTyr: 1.835 ± 0.051	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2958 proteins (1005557 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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