Amino acid dipepetide frequency for Atlantibacter hermannii NBRC 105704

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.64AlaAla: 10.64 ± 0.121	1.153AlaCys: 1.153 ± 0.034	5.159AlaAsp: 5.159 ± 0.125	5.504AlaGlu: 5.504 ± 0.074	3.78AlaPhe: 3.78 ± 0.066	7.815AlaGly: 7.815 ± 0.093	1.927AlaHis: 1.927 ± 0.042	5.917AlaIle: 5.917 ± 0.07	3.801AlaLys: 3.801 ± 0.064	12.45AlaLeu: 12.45 ± 0.121	3.084AlaMet: 3.084 ± 0.054	3.16AlaAsn: 3.16 ± 0.055	3.902AlaPro: 3.902 ± 0.065	4.683AlaGln: 4.683 ± 0.07	5.98AlaArg: 5.98 ± 0.083	5.79AlaSer: 5.79 ± 0.077	4.892AlaThr: 4.892 ± 0.068	6.916AlaVal: 6.916 ± 0.078	1.725AlaTrp: 1.725 ± 0.034	1.994AlaTyr: 1.994 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.07CysAla: 1.07 ± 0.03	0.178CysCys: 0.178 ± 0.011	0.651CysAsp: 0.651 ± 0.024	0.617CysGlu: 0.617 ± 0.022	0.429CysPhe: 0.429 ± 0.016	1.096CysGly: 1.096 ± 0.03	0.339CysHis: 0.339 ± 0.017	0.556CysIle: 0.556 ± 0.021	0.331CysLys: 0.331 ± 0.018	0.989CysLeu: 0.989 ± 0.027	0.252CysMet: 0.252 ± 0.013	0.326CysAsn: 0.326 ± 0.017	0.552CysPro: 0.552 ± 0.021	0.466CysGln: 0.466 ± 0.02	0.631CysArg: 0.631 ± 0.026	0.617CysSer: 0.617 ± 0.024	0.463CysThr: 0.463 ± 0.023	0.777CysVal: 0.777 ± 0.028	0.178CysTrp: 0.178 ± 0.01	0.317CysTyr: 0.317 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.769AspAla: 5.769 ± 0.123	0.506AspCys: 0.506 ± 0.021	3.003AspAsp: 3.003 ± 0.056	3.584AspGlu: 3.584 ± 0.058	2.08AspPhe: 2.08 ± 0.042	3.906AspGly: 3.906 ± 0.075	1.013AspHis: 1.013 ± 0.031	3.481AspIle: 3.481 ± 0.052	2.474AspLys: 2.474 ± 0.046	4.544AspLeu: 4.544 ± 0.058	1.379AspMet: 1.379 ± 0.034	2.199AspAsn: 2.199 ± 0.045	2.32AspPro: 2.32 ± 0.046	1.647AspGln: 1.647 ± 0.041	2.762AspArg: 2.762 ± 0.051	2.794AspSer: 2.794 ± 0.053	2.61AspThr: 2.61 ± 0.049	3.956AspVal: 3.956 ± 0.06	0.837AspTrp: 0.837 ± 0.026	1.87AspTyr: 1.87 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	5.513GluAla: 5.513 ± 0.067	0.475GluCys: 0.475 ± 0.018	2.343GluAsp: 2.343 ± 0.042	3.318GluGlu: 3.318 ± 0.057	1.806GluPhe: 1.806 ± 0.031	3.651GluGly: 3.651 ± 0.054	1.394GluHis: 1.394 ± 0.037	3.26GluIle: 3.26 ± 0.057	3.15GluLys: 3.15 ± 0.056	5.761GluLeu: 5.761 ± 0.078	1.794GluMet: 1.794 ± 0.043	2.357GluAsn: 2.357 ± 0.036	2.283GluPro: 2.283 ± 0.047	3.392GluGln: 3.392 ± 0.059	3.641GluArg: 3.641 ± 0.059	2.951GluSer: 2.951 ± 0.049	2.998GluThr: 2.998 ± 0.055	3.727GluVal: 3.727 ± 0.059	0.802GluTrp: 0.802 ± 0.026	1.405GluTyr: 1.405 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.731PheAla: 3.731 ± 0.05	0.514PheCys: 0.514 ± 0.022	2.363PheAsp: 2.363 ± 0.047	1.761PheGlu: 1.761 ± 0.038	1.654PhePhe: 1.654 ± 0.039	3.213PheGly: 3.213 ± 0.056	0.816PheHis: 0.816 ± 0.024	2.542PheIle: 2.542 ± 0.049	1.282PheLys: 1.282 ± 0.032	3.22PheLeu: 3.22 ± 0.051	1.001PheMet: 1.001 ± 0.03	1.758PheAsn: 1.758 ± 0.038	1.515PhePro: 1.515 ± 0.037	1.115PheGln: 1.115 ± 0.03	1.945PheArg: 1.945 ± 0.039	3.054PheSer: 3.054 ± 0.054	2.528PheThr: 2.528 ± 0.044	2.508PheVal: 2.508 ± 0.05	0.622PheTrp: 0.622 ± 0.021	1.195PheTyr: 1.195 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	6.565GlyAla: 6.565 ± 0.081	1.034GlyCys: 1.034 ± 0.029	3.917GlyAsp: 3.917 ± 0.068	4.69GlyGlu: 4.69 ± 0.059	3.331GlyPhe: 3.331 ± 0.05	5.417GlyGly: 5.417 ± 0.083	1.672GlyHis: 1.672 ± 0.038	5.039GlyIle: 5.039 ± 0.063	3.941GlyLys: 3.941 ± 0.06	7.619GlyLeu: 7.619 ± 0.092	2.451GlyMet: 2.451 ± 0.05	2.796GlyAsn: 2.796 ± 0.075	2.068GlyPro: 2.068 ± 0.042	2.994GlyGln: 2.994 ± 0.054	3.737GlyArg: 3.737 ± 0.052	4.126GlySer: 4.126 ± 0.076	3.773GlyThr: 3.773 ± 0.076	6.011GlyVal: 6.011 ± 0.072	1.272GlyTrp: 1.272 ± 0.032	2.594GlyTyr: 2.594 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.01HisAla: 2.01 ± 0.041	0.336HisCys: 0.336 ± 0.016	1.21HisAsp: 1.21 ± 0.035	1.168HisGlu: 1.168 ± 0.031	1.074HisPhe: 1.074 ± 0.027	1.729HisGly: 1.729 ± 0.039	0.849HisHis: 0.849 ± 0.028	1.369HisIle: 1.369 ± 0.032	0.738HisLys: 0.738 ± 0.022	2.265HisLeu: 2.265 ± 0.04	0.527HisMet: 0.527 ± 0.018	0.83HisAsn: 0.83 ± 0.027	1.375HisPro: 1.375 ± 0.036	1.204HisGln: 1.204 ± 0.031	1.284HisArg: 1.284 ± 0.034	1.249HisSer: 1.249 ± 0.029	1.069HisThr: 1.069 ± 0.026	1.341HisVal: 1.341 ± 0.029	0.398HisTrp: 0.398 ± 0.015	0.873HisTyr: 0.873 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.453IleAla: 6.453 ± 0.066	0.646IleCys: 0.646 ± 0.025	3.577IleAsp: 3.577 ± 0.051	3.286IleGlu: 3.286 ± 0.061	1.948IlePhe: 1.948 ± 0.046	4.615IleGly: 4.615 ± 0.064	1.195IleHis: 1.195 ± 0.032	3.284IleIle: 3.284 ± 0.059	2.321IleLys: 2.321 ± 0.047	4.865IleLeu: 4.865 ± 0.074	1.219IleMet: 1.219 ± 0.035	2.653IleAsn: 2.653 ± 0.044	2.712IlePro: 2.712 ± 0.045	1.822IleGln: 1.822 ± 0.037	2.993IleArg: 2.993 ± 0.051	3.705IleSer: 3.705 ± 0.06	3.639IleThr: 3.639 ± 0.068	3.957IleVal: 3.957 ± 0.056	0.685IleTrp: 0.685 ± 0.021	1.458IleTyr: 1.458 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.291LysAla: 4.291 ± 0.06	0.273LysCys: 0.273 ± 0.014	1.933LysAsp: 1.933 ± 0.04	2.333LysGlu: 2.333 ± 0.052	1.099LysPhe: 1.099 ± 0.025	2.932LysGly: 2.932 ± 0.049	0.887LysHis: 0.887 ± 0.024	2.303LysIle: 2.303 ± 0.048	2.111LysLys: 2.111 ± 0.051	4.156LysLeu: 4.156 ± 0.065	1.175LysMet: 1.175 ± 0.027	1.653LysAsn: 1.653 ± 0.035	2.217LysPro: 2.217 ± 0.04	1.883LysGln: 1.883 ± 0.041	2.547LysArg: 2.547 ± 0.056	2.269LysSer: 2.269 ± 0.037	2.458LysThr: 2.458 ± 0.04	2.82LysVal: 2.82 ± 0.049	0.454LysTrp: 0.454 ± 0.019	1.085LysTyr: 1.085 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.675LeuAla: 11.675 ± 0.108	1.311LeuCys: 1.311 ± 0.034	5.538LeuAsp: 5.538 ± 0.066	5.467LeuGlu: 5.467 ± 0.076	4.228LeuPhe: 4.228 ± 0.068	7.268LeuGly: 7.268 ± 0.084	2.255LeuHis: 2.255 ± 0.046	5.955LeuIle: 5.955 ± 0.075	4.42LeuLys: 4.42 ± 0.059	11.782LeuLeu: 11.782 ± 0.147	3.015LeuMet: 3.015 ± 0.048	4.342LeuAsn: 4.342 ± 0.058	5.624LeuPro: 5.624 ± 0.077	3.95LeuGln: 3.95 ± 0.064	6.182LeuArg: 6.182 ± 0.086	7.098LeuSer: 7.098 ± 0.072	6.525LeuThr: 6.525 ± 0.075	7.059LeuVal: 7.059 ± 0.084	1.481LeuTrp: 1.481 ± 0.04	2.557LeuTyr: 2.557 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.987MetAla: 2.987 ± 0.054	0.209MetCys: 0.209 ± 0.011	1.245MetAsp: 1.245 ± 0.029	1.252MetGlu: 1.252 ± 0.029	0.908MetPhe: 0.908 ± 0.028	1.915MetGly: 1.915 ± 0.043	0.537MetHis: 0.537 ± 0.02	1.526MetIle: 1.526 ± 0.039	1.379MetLys: 1.379 ± 0.033	3.176MetLeu: 3.176 ± 0.049	0.942MetMet: 0.942 ± 0.029	1.108MetAsn: 1.108 ± 0.03	1.383MetPro: 1.383 ± 0.028	1.197MetGln: 1.197 ± 0.033	1.514MetArg: 1.514 ± 0.032	1.847MetSer: 1.847 ± 0.037	1.772MetThr: 1.772 ± 0.039	2.007MetVal: 2.007 ± 0.045	0.247MetTrp: 0.247 ± 0.015	0.504MetTyr: 0.504 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.764AsnAla: 3.764 ± 0.051	0.334AsnCys: 0.334 ± 0.016	2.079AsnAsp: 2.079 ± 0.036	1.925AsnGlu: 1.925 ± 0.035	1.328AsnPhe: 1.328 ± 0.036	3.1AsnGly: 3.1 ± 0.067	0.842AsnHis: 0.842 ± 0.024	2.186AsnIle: 2.186 ± 0.044	1.494AsnLys: 1.494 ± 0.036	3.506AsnLeu: 3.506 ± 0.052	0.903AsnMet: 0.903 ± 0.028	1.626AsnAsn: 1.626 ± 0.047	2.194AsnPro: 2.194 ± 0.04	1.705AsnGln: 1.705 ± 0.039	2.073AsnArg: 2.073 ± 0.039	1.953AsnSer: 1.953 ± 0.043	1.991AsnThr: 1.991 ± 0.048	2.613AsnVal: 2.613 ± 0.054	0.574AsnTrp: 0.574 ± 0.021	1.141AsnTyr: 1.141 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	4.75ProAla: 4.75 ± 0.07	0.417ProCys: 0.417 ± 0.017	2.981ProAsp: 2.981 ± 0.056	3.346ProGlu: 3.346 ± 0.049	1.883ProPhe: 1.883 ± 0.036	3.691ProGly: 3.691 ± 0.053	1.053ProHis: 1.053 ± 0.028	1.742ProIle: 1.742 ± 0.039	1.447ProLys: 1.447 ± 0.032	5.197ProLeu: 5.197 ± 0.077	1.132ProMet: 1.132 ± 0.03	1.292ProAsn: 1.292 ± 0.03	1.737ProPro: 1.737 ± 0.045	2.279ProGln: 2.279 ± 0.042	2.086ProArg: 2.086 ± 0.044	2.174ProSer: 2.174 ± 0.041	2.122ProThr: 2.122 ± 0.045	4.179ProVal: 4.179 ± 0.06	0.801ProTrp: 0.801 ± 0.027	1.112ProTyr: 1.112 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.771GlnAla: 4.771 ± 0.065	0.422GlnCys: 0.422 ± 0.02	1.896GlnAsp: 1.896 ± 0.04	2.133GlnGlu: 2.133 ± 0.043	1.455GlnPhe: 1.455 ± 0.031	3.148GlnGly: 3.148 ± 0.05	1.245GlnHis: 1.245 ± 0.033	2.234GlnIle: 2.234 ± 0.04	1.803GlnLys: 1.803 ± 0.04	4.899GlnLeu: 4.899 ± 0.067	1.161GlnMet: 1.161 ± 0.03	1.439GlnAsn: 1.439 ± 0.036	2.233GlnPro: 2.233 ± 0.044	3.249GlnGln: 3.249 ± 0.064	3.076GlnArg: 3.076 ± 0.058	2.289GlnSer: 2.289 ± 0.051	2.313GlnThr: 2.313 ± 0.049	2.947GlnVal: 2.947 ± 0.055	0.675GlnTrp: 0.675 ± 0.025	1.167GlnTyr: 1.167 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	4.843ArgAla: 4.843 ± 0.065	0.62ArgCys: 0.62 ± 0.024	3.181ArgAsp: 3.181 ± 0.05	3.869ArgGlu: 3.869 ± 0.062	2.626ArgPhe: 2.626 ± 0.053	3.454ArgGly: 3.454 ± 0.055	1.643ArgHis: 1.643 ± 0.041	3.416ArgIle: 3.416 ± 0.053	2.301ArgLys: 2.301 ± 0.042	6.49ArgLeu: 6.49 ± 0.087	1.611ArgMet: 1.611 ± 0.036	2.126ArgAsn: 2.126 ± 0.045	2.294ArgPro: 2.294 ± 0.038	3.056ArgGln: 3.056 ± 0.06	3.572ArgArg: 3.572 ± 0.061	2.752ArgSer: 2.752 ± 0.047	2.587ArgThr: 2.587 ± 0.046	3.9ArgVal: 3.9 ± 0.051	0.982ArgTrp: 0.982 ± 0.031	2.183ArgTyr: 2.183 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.67SerAla: 5.67 ± 0.076	0.552SerCys: 0.552 ± 0.021	3.055SerAsp: 3.055 ± 0.052	3.232SerGlu: 3.232 ± 0.048	2.235SerPhe: 2.235 ± 0.045	5.316SerGly: 5.316 ± 0.091	1.403SerHis: 1.403 ± 0.03	2.788SerIle: 2.788 ± 0.044	1.9SerLys: 1.9 ± 0.038	6.632SerLeu: 6.632 ± 0.076	1.499SerMet: 1.499 ± 0.034	1.77SerAsn: 1.77 ± 0.045	2.619SerPro: 2.619 ± 0.045	2.594SerGln: 2.594 ± 0.048	3.498SerArg: 3.498 ± 0.049	3.44SerSer: 3.44 ± 0.069	2.897SerThr: 2.897 ± 0.054	4.355SerVal: 4.355 ± 0.056	0.945SerTrp: 0.945 ± 0.031	1.508SerTyr: 1.508 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	5.069ThrAla: 5.069 ± 0.066	0.514ThrCys: 0.514 ± 0.022	2.677ThrAsp: 2.677 ± 0.057	2.612ThrGlu: 2.612 ± 0.043	2.015ThrPhe: 2.015 ± 0.04	4.699ThrGly: 4.699 ± 0.069	1.326ThrHis: 1.326 ± 0.034	2.795ThrIle: 2.795 ± 0.054	1.45ThrLys: 1.45 ± 0.034	7.581ThrLeu: 7.581 ± 0.094	1.163ThrMet: 1.163 ± 0.028	1.554ThrAsn: 1.554 ± 0.041	3.299ThrPro: 3.299 ± 0.05	2.214ThrGln: 2.214 ± 0.045	3.261ThrArg: 3.261 ± 0.046	2.829ThrSer: 2.829 ± 0.053	2.893ThrThr: 2.893 ± 0.06	4.112ThrVal: 4.112 ± 0.092	0.877ThrTrp: 0.877 ± 0.028	1.097ThrTyr: 1.097 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.246ValAla: 7.246 ± 0.08	0.788ValCys: 0.788 ± 0.024	3.754ValAsp: 3.754 ± 0.058	4.071ValGlu: 4.071 ± 0.058	2.584ValPhe: 2.584 ± 0.045	4.93ValGly: 4.93 ± 0.068	1.292ValHis: 1.292 ± 0.031	4.612ValIle: 4.612 ± 0.071	3.096ValLys: 3.096 ± 0.052	7.254ValLeu: 7.254 ± 0.084	2.328ValMet: 2.328 ± 0.042	2.86ValAsn: 2.86 ± 0.059	3.053ValPro: 3.053 ± 0.058	2.312ValGln: 2.312 ± 0.045	3.746ValArg: 3.746 ± 0.061	4.534ValSer: 4.534 ± 0.06	4.56ValThr: 4.56 ± 0.098	5.743ValVal: 5.743 ± 0.078	1.011ValTrp: 1.011 ± 0.032	1.717ValTyr: 1.717 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.027TrpAla: 1.027 ± 0.028	0.186TrpCys: 0.186 ± 0.012	0.657TrpAsp: 0.657 ± 0.022	0.634TrpGlu: 0.634 ± 0.026	0.712TrpPhe: 0.712 ± 0.024	0.91TrpGly: 0.91 ± 0.028	0.495TrpHis: 0.495 ± 0.022	0.741TrpIle: 0.741 ± 0.028	0.53TrpLys: 0.53 ± 0.02	2.372TrpLeu: 2.372 ± 0.047	0.452TrpMet: 0.452 ± 0.019	0.502TrpAsn: 0.502 ± 0.018	0.719TrpPro: 0.719 ± 0.025	1.159TrpGln: 1.159 ± 0.033	1.152TrpArg: 1.152 ± 0.036	0.8TrpSer: 0.8 ± 0.028	0.599TrpThr: 0.599 ± 0.022	0.961TrpVal: 0.961 ± 0.027	0.24TrpTrp: 0.24 ± 0.014	0.414TrpTyr: 0.414 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.43TyrAla: 2.43 ± 0.042	0.366TyrCys: 0.366 ± 0.015	1.515TyrAsp: 1.515 ± 0.037	1.219TyrGlu: 1.219 ± 0.027	1.162TyrPhe: 1.162 ± 0.029	2.241TyrGly: 2.241 ± 0.039	0.713TyrHis: 0.713 ± 0.023	1.287TyrIle: 1.287 ± 0.032	0.911TyrLys: 0.911 ± 0.024	2.976TyrLeu: 2.976 ± 0.047	0.564TyrMet: 0.564 ± 0.021	0.982TyrAsn: 0.982 ± 0.027	1.323TyrPro: 1.323 ± 0.035	1.634TyrGln: 1.634 ± 0.035	1.826TyrArg: 1.826 ± 0.041	1.637TyrSer: 1.637 ± 0.041	1.348TyrThr: 1.348 ± 0.029	1.604TyrVal: 1.604 ± 0.038	0.454TyrTrp: 0.454 ± 0.021	0.858TyrTyr: 0.858 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4159 proteins (1323175 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---