Amino acid dipepetide frequency for Beihai tombus-like virus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.148AlaAla: 5.148 ± 1.649
0.0AlaCys: 0.0 ± 0.0
1.931AlaAsp: 1.931 ± 0.043
3.861AlaGlu: 3.861 ± 0.087
1.931AlaPhe: 1.931 ± 0.963
1.931AlaGly: 1.931 ± 0.963
0.644AlaHis: 0.644 ± 0.321
2.574AlaIle: 2.574 ± 1.284
5.792AlaLys: 5.792 ± 1.97
6.435AlaLeu: 6.435 ± 0.468
2.574AlaMet: 2.574 ± 1.475
3.218AlaAsn: 3.218 ± 0.686
3.218AlaPro: 3.218 ± 0.234
3.861AlaGln: 3.861 ± 0.087
5.792AlaArg: 5.792 ± 1.709
5.792AlaSer: 5.792 ± 0.13
5.792AlaThr: 5.792 ± 0.13
5.148AlaVal: 5.148 ± 2.568
0.644AlaTrp: 0.644 ± 0.321
0.644AlaTyr: 0.644 ± 0.321
0.0AlaXaa: 0.0 ± 0.0
Cys
0.644CysAla: 0.644 ± 0.599
0.0CysCys: 0.0 ± 0.0
1.931CysAsp: 1.931 ± 0.043
0.644CysGlu: 0.644 ± 0.599
0.644CysPhe: 0.644 ± 0.321
0.644CysGly: 0.644 ± 0.321
1.931CysHis: 1.931 ± 0.043
0.0CysIle: 0.0 ± 0.0
1.287CysLys: 1.287 ± 0.642
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.644CysPro: 0.644 ± 0.321
1.287CysGln: 1.287 ± 0.278
0.0CysArg: 0.0 ± 0.0
1.287CysSer: 1.287 ± 0.642
0.644CysThr: 0.644 ± 0.321
1.287CysVal: 1.287 ± 0.278
0.0CysTrp: 0.0 ± 0.0
0.644CysTyr: 0.644 ± 0.321
0.0CysXaa: 0.0 ± 0.0
Asp
3.218AspAla: 3.218 ± 1.605
0.0AspCys: 0.0 ± 0.0
5.792AspAsp: 5.792 ± 0.13
3.861AspGlu: 3.861 ± 1.007
3.861AspPhe: 3.861 ± 0.087
2.574AspGly: 2.574 ± 0.555
1.931AspHis: 1.931 ± 0.876
1.931AspIle: 1.931 ± 0.876
3.218AspLys: 3.218 ± 1.154
3.861AspLeu: 3.861 ± 1.007
1.287AspMet: 1.287 ± 0.278
2.574AspAsn: 2.574 ± 0.555
3.218AspPro: 3.218 ± 0.686
0.0AspGln: 0.0 ± 0.0
3.861AspArg: 3.861 ± 0.087
3.218AspSer: 3.218 ± 0.686
6.435AspThr: 6.435 ± 1.388
5.148AspVal: 5.148 ± 1.649
1.287AspTrp: 1.287 ± 1.197
3.861AspTyr: 3.861 ± 1.752
0.0AspXaa: 0.0 ± 0.0
Glu
2.574GluAla: 2.574 ± 0.555
2.574GluCys: 2.574 ± 0.555
3.218GluAsp: 3.218 ± 1.154
4.505GluGlu: 4.505 ± 1.431
3.218GluPhe: 3.218 ± 1.154
3.861GluGly: 3.861 ± 0.833
2.574GluHis: 2.574 ± 1.284
1.287GluIle: 1.287 ± 1.197
3.861GluLys: 3.861 ± 0.087
2.574GluLeu: 2.574 ± 0.365
2.574GluMet: 2.574 ± 0.555
0.644GluAsn: 0.644 ± 0.321
3.861GluPro: 3.861 ± 1.007
1.931GluGln: 1.931 ± 0.043
4.505GluArg: 4.505 ± 0.512
2.574GluSer: 2.574 ± 0.555
1.931GluThr: 1.931 ± 0.043
4.505GluVal: 4.505 ± 1.328
1.931GluTrp: 1.931 ± 0.043
3.861GluTyr: 3.861 ± 1.007
0.0GluXaa: 0.0 ± 0.0
Phe
2.574PheAla: 2.574 ± 0.365
0.644PheCys: 0.644 ± 0.599
3.861PheAsp: 3.861 ± 0.087
3.218PheGlu: 3.218 ± 2.073
0.644PhePhe: 0.644 ± 0.321
1.931PheGly: 1.931 ± 0.043
0.644PheHis: 0.644 ± 0.321
2.574PheIle: 2.574 ± 0.365
3.861PheLys: 3.861 ± 0.833
1.931PheLeu: 1.931 ± 0.876
1.287PheMet: 1.287 ± 0.278
1.931PheAsn: 1.931 ± 0.876
2.574PhePro: 2.574 ± 0.365
1.931PheGln: 1.931 ± 0.043
3.861PheArg: 3.861 ± 1.007
4.505PheSer: 4.505 ± 0.408
5.148PheThr: 5.148 ± 0.191
4.505PheVal: 4.505 ± 2.247
1.287PheTrp: 1.287 ± 0.642
2.574PheTyr: 2.574 ± 1.475
0.0PheXaa: 0.0 ± 0.0
Gly
7.079GlyAla: 7.079 ± 0.773
0.0GlyCys: 0.0 ± 0.0
3.861GlyAsp: 3.861 ± 0.833
1.931GlyGlu: 1.931 ± 0.043
5.792GlyPhe: 5.792 ± 0.789
1.931GlyGly: 1.931 ± 0.876
1.931GlyHis: 1.931 ± 0.963
1.931GlyIle: 1.931 ± 0.963
2.574GlyLys: 2.574 ± 0.555
5.792GlyLeu: 5.792 ± 0.789
2.574GlyMet: 2.574 ± 1.475
4.505GlyAsn: 4.505 ± 0.408
3.218GlyPro: 3.218 ± 1.605
2.574GlyGln: 2.574 ± 1.284
0.0GlyArg: 0.0 ± 0.0
2.574GlySer: 2.574 ± 1.284
6.435GlyThr: 6.435 ± 0.468
3.861GlyVal: 3.861 ± 0.087
0.644GlyTrp: 0.644 ± 0.321
1.287GlyTyr: 1.287 ± 0.278
0.0GlyXaa: 0.0 ± 0.0
His
0.644HisAla: 0.644 ± 0.321
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.644HisGlu: 0.644 ± 0.321
1.931HisPhe: 1.931 ± 0.963
0.644HisGly: 0.644 ± 0.321
1.931HisHis: 1.931 ± 0.876
1.287HisIle: 1.287 ± 0.278
4.505HisLys: 4.505 ± 2.351
1.931HisLeu: 1.931 ± 0.876
0.644HisMet: 0.644 ± 0.599
0.644HisAsn: 0.644 ± 0.321
0.644HisPro: 0.644 ± 0.321
1.931HisGln: 1.931 ± 0.043
1.287HisArg: 1.287 ± 1.197
1.287HisSer: 1.287 ± 0.278
1.931HisThr: 1.931 ± 0.963
1.287HisVal: 1.287 ± 0.278
0.644HisTrp: 0.644 ± 0.599
0.644HisTyr: 0.644 ± 0.599
0.0HisXaa: 0.0 ± 0.0
Ile
3.218IleAla: 3.218 ± 0.234
1.287IleCys: 1.287 ± 0.278
3.218IleAsp: 3.218 ± 0.234
3.861IleGlu: 3.861 ± 1.752
3.218IlePhe: 3.218 ± 0.686
3.861IleGly: 3.861 ± 0.087
0.644IleHis: 0.644 ± 0.321
1.931IleIle: 1.931 ± 0.043
4.505IleLys: 4.505 ± 1.431
4.505IleLeu: 4.505 ± 1.328
1.931IleMet: 1.931 ± 0.963
2.574IleAsn: 2.574 ± 0.555
3.218IlePro: 3.218 ± 1.605
0.0IleGln: 0.0 ± 0.0
1.287IleArg: 1.287 ± 0.642
0.644IleSer: 0.644 ± 0.321
4.505IleThr: 4.505 ± 0.408
1.287IleVal: 1.287 ± 0.278
0.644IleTrp: 0.644 ± 0.321
3.218IleTyr: 3.218 ± 0.234
0.0IleXaa: 0.0 ± 0.0
Lys
5.148LysAla: 5.148 ± 1.649
0.644LysCys: 0.644 ± 0.321
5.792LysAsp: 5.792 ± 1.709
5.148LysGlu: 5.148 ± 0.191
3.218LysPhe: 3.218 ± 1.154
4.505LysGly: 4.505 ± 3.271
0.644LysHis: 0.644 ± 0.599
1.931LysIle: 1.931 ± 0.876
3.861LysLys: 3.861 ± 1.752
8.366LysLeu: 8.366 ± 3.184
3.861LysMet: 3.861 ± 2.672
5.148LysAsn: 5.148 ± 2.03
1.931LysPro: 1.931 ± 0.043
1.931LysGln: 1.931 ± 0.043
4.505LysArg: 4.505 ± 1.328
3.218LysSer: 3.218 ± 0.234
5.148LysThr: 5.148 ± 0.191
4.505LysVal: 4.505 ± 1.328
1.287LysTrp: 1.287 ± 0.278
4.505LysTyr: 4.505 ± 0.512
0.0LysXaa: 0.0 ± 0.0
Leu
4.505LeuAla: 4.505 ± 1.328
0.644LeuCys: 0.644 ± 0.321
3.861LeuAsp: 3.861 ± 1.752
2.574LeuGlu: 2.574 ± 0.365
5.792LeuPhe: 5.792 ± 0.13
5.792LeuGly: 5.792 ± 0.13
1.931LeuHis: 1.931 ± 0.876
5.792LeuIle: 5.792 ± 1.05
2.574LeuLys: 2.574 ± 0.365
5.792LeuLeu: 5.792 ± 1.709
1.931LeuMet: 1.931 ± 0.043
4.505LeuAsn: 4.505 ± 1.328
5.792LeuPro: 5.792 ± 0.789
2.574LeuGln: 2.574 ± 0.365
2.574LeuArg: 2.574 ± 0.555
7.079LeuSer: 7.079 ± 1.067
3.861LeuThr: 3.861 ± 1.007
3.861LeuVal: 3.861 ± 0.833
0.0LeuTrp: 0.0 ± 0.0
3.861LeuTyr: 3.861 ± 1.752
0.0LeuXaa: 0.0 ± 0.0
Met
2.574MetAla: 2.574 ± 1.284
1.931MetCys: 1.931 ± 0.043
0.644MetAsp: 0.644 ± 0.321
2.574MetGlu: 2.574 ± 2.394
1.931MetPhe: 1.931 ± 0.876
1.287MetGly: 1.287 ± 0.642
1.287MetHis: 1.287 ± 0.278
1.287MetIle: 1.287 ± 0.278
3.218MetLys: 3.218 ± 0.234
1.287MetLeu: 1.287 ± 0.278
1.931MetMet: 1.931 ± 0.963
0.0MetAsn: 0.0 ± 0.0
2.574MetPro: 2.574 ± 0.555
0.644MetGln: 0.644 ± 0.599
2.574MetArg: 2.574 ± 1.475
1.931MetSer: 1.931 ± 0.876
2.574MetThr: 2.574 ± 0.555
0.644MetVal: 0.644 ± 0.599
0.0MetTrp: 0.0 ± 0.0
0.644MetTyr: 0.644 ± 0.599
0.0MetXaa: 0.0 ± 0.0
Asn
3.861AsnAla: 3.861 ± 0.833
0.644AsnCys: 0.644 ± 0.321
3.218AsnAsp: 3.218 ± 1.605
1.931AsnGlu: 1.931 ± 0.963
2.574AsnPhe: 2.574 ± 0.365
3.218AsnGly: 3.218 ± 0.686
1.287AsnHis: 1.287 ± 1.197
2.574AsnIle: 2.574 ± 0.365
4.505AsnLys: 4.505 ± 1.431
3.218AsnLeu: 3.218 ± 0.686
1.287AsnMet: 1.287 ± 0.182
2.574AsnAsn: 2.574 ± 0.365
1.931AsnPro: 1.931 ± 0.963
1.287AsnGln: 1.287 ± 0.642
1.287AsnArg: 1.287 ± 1.197
3.218AsnSer: 3.218 ± 0.234
2.574AsnThr: 2.574 ± 1.284
3.861AsnVal: 3.861 ± 0.087
0.644AsnTrp: 0.644 ± 0.599
0.644AsnTyr: 0.644 ± 0.321
0.0AsnXaa: 0.0 ± 0.0
Pro
3.218ProAla: 3.218 ± 0.686
0.644ProCys: 0.644 ± 0.321
3.218ProAsp: 3.218 ± 0.234
4.505ProGlu: 4.505 ± 0.408
0.644ProPhe: 0.644 ± 0.599
5.148ProGly: 5.148 ± 0.729
0.644ProHis: 0.644 ± 0.599
1.931ProIle: 1.931 ± 0.963
3.218ProLys: 3.218 ± 0.234
4.505ProLeu: 4.505 ± 1.328
0.644ProMet: 0.644 ± 0.599
1.931ProAsn: 1.931 ± 0.963
2.574ProPro: 2.574 ± 0.555
1.931ProGln: 1.931 ± 0.043
3.218ProArg: 3.218 ± 1.605
1.931ProSer: 1.931 ± 0.963
3.218ProThr: 3.218 ± 0.686
5.792ProVal: 5.792 ± 1.709
1.287ProTrp: 1.287 ± 0.278
0.644ProTyr: 0.644 ± 0.321
0.0ProXaa: 0.0 ± 0.0
Gln
3.218GlnAla: 3.218 ± 1.154
0.0GlnCys: 0.0 ± 0.0
3.218GlnAsp: 3.218 ± 1.605
0.644GlnGlu: 0.644 ± 0.321
3.218GlnPhe: 3.218 ± 0.234
2.574GlnGly: 2.574 ± 0.365
0.0GlnHis: 0.0 ± 0.0
1.931GlnIle: 1.931 ± 0.043
1.931GlnLys: 1.931 ± 0.043
3.861GlnLeu: 3.861 ± 0.087
1.287GlnMet: 1.287 ± 0.642
2.574GlnAsn: 2.574 ± 0.365
0.644GlnPro: 0.644 ± 0.321
0.644GlnGln: 0.644 ± 0.321
1.931GlnArg: 1.931 ± 0.963
1.287GlnSer: 1.287 ± 0.278
1.287GlnThr: 1.287 ± 0.278
0.644GlnVal: 0.644 ± 0.321
0.644GlnTrp: 0.644 ± 0.321
0.644GlnTyr: 0.644 ± 0.321
0.0GlnXaa: 0.0 ± 0.0
Arg
3.861ArgAla: 3.861 ± 1.007
0.644ArgCys: 0.644 ± 0.321
3.861ArgAsp: 3.861 ± 0.087
4.505ArgGlu: 4.505 ± 1.328
1.931ArgPhe: 1.931 ± 0.043
1.287ArgGly: 1.287 ± 0.278
1.287ArgHis: 1.287 ± 0.278
4.505ArgIle: 4.505 ± 2.247
6.435ArgLys: 6.435 ± 3.227
2.574ArgLeu: 2.574 ± 0.365
2.574ArgMet: 2.574 ± 0.365
3.218ArgAsn: 3.218 ± 0.686
2.574ArgPro: 2.574 ± 0.555
2.574ArgGln: 2.574 ± 0.365
3.218ArgArg: 3.218 ± 1.605
1.287ArgSer: 1.287 ± 0.278
3.218ArgThr: 3.218 ± 0.234
3.861ArgVal: 3.861 ± 1.752
0.0ArgTrp: 0.0 ± 0.0
0.644ArgTyr: 0.644 ± 0.599
0.0ArgXaa: 0.0 ± 0.0
Ser
2.574SerAla: 2.574 ± 0.555
0.644SerCys: 0.644 ± 0.599
4.505SerAsp: 4.505 ± 0.408
3.861SerGlu: 3.861 ± 1.926
1.931SerPhe: 1.931 ± 0.876
6.435SerGly: 6.435 ± 1.371
1.287SerHis: 1.287 ± 0.278
3.218SerIle: 3.218 ± 0.686
1.931SerLys: 1.931 ± 0.043
6.435SerLeu: 6.435 ± 0.452
0.644SerMet: 0.644 ± 0.599
1.931SerAsn: 1.931 ± 0.043
2.574SerPro: 2.574 ± 0.555
1.931SerGln: 1.931 ± 0.043
1.287SerArg: 1.287 ± 0.642
5.148SerSer: 5.148 ± 0.191
2.574SerThr: 2.574 ± 1.284
4.505SerVal: 4.505 ± 1.328
2.574SerTrp: 2.574 ± 2.394
1.287SerTyr: 1.287 ± 0.278
0.0SerXaa: 0.0 ± 0.0
Thr
5.792ThrAla: 5.792 ± 1.97
1.287ThrCys: 1.287 ± 0.642
5.148ThrAsp: 5.148 ± 1.649
0.0ThrGlu: 0.0 ± 0.0
0.644ThrPhe: 0.644 ± 0.321
7.079ThrGly: 7.079 ± 0.147
1.287ThrHis: 1.287 ± 0.278
3.861ThrIle: 3.861 ± 2.672
3.218ThrLys: 3.218 ± 0.234
5.148ThrLeu: 5.148 ± 0.729
1.931ThrMet: 1.931 ± 0.876
1.931ThrAsn: 1.931 ± 0.876
5.792ThrPro: 5.792 ± 0.789
2.574ThrGln: 2.574 ± 1.284
5.792ThrArg: 5.792 ± 0.13
5.148ThrSer: 5.148 ± 0.729
1.931ThrThr: 1.931 ± 0.963
3.861ThrVal: 3.861 ± 1.926
2.574ThrTrp: 2.574 ± 1.475
3.861ThrTyr: 3.861 ± 1.926
0.0ThrXaa: 0.0 ± 0.0
Val
3.218ValAla: 3.218 ± 0.686
1.287ValCys: 1.287 ± 0.642
2.574ValAsp: 2.574 ± 0.555
3.861ValGlu: 3.861 ± 0.087
4.505ValPhe: 4.505 ± 1.328
1.931ValGly: 1.931 ± 0.963
1.287ValHis: 1.287 ± 1.197
4.505ValIle: 4.505 ± 0.408
10.296ValLys: 10.296 ± 1.301
5.148ValLeu: 5.148 ± 0.191
0.644ValMet: 0.644 ± 0.599
5.148ValAsn: 5.148 ± 2.568
2.574ValPro: 2.574 ± 0.365
1.931ValGln: 1.931 ± 0.043
3.861ValArg: 3.861 ± 1.007
2.574ValSer: 2.574 ± 1.284
5.148ValThr: 5.148 ± 0.191
5.148ValVal: 5.148 ± 1.649
0.644ValTrp: 0.644 ± 0.321
1.287ValTyr: 1.287 ± 0.642
0.644ValXaa: 0.644 ± 0.321
Trp
1.931TrpAla: 1.931 ± 0.043
0.0TrpCys: 0.0 ± 0.0
0.644TrpAsp: 0.644 ± 0.599
1.287TrpGlu: 1.287 ± 0.278
1.287TrpPhe: 1.287 ± 1.197
0.644TrpGly: 0.644 ± 0.321
0.0TrpHis: 0.0 ± 0.0
0.644TrpIle: 0.644 ± 0.599
3.218TrpLys: 3.218 ± 2.073
0.644TrpLeu: 0.644 ± 0.599
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.644TrpPro: 0.644 ± 0.321
0.0TrpGln: 0.0 ± 0.0
1.287TrpArg: 1.287 ± 0.278
0.644TrpSer: 0.644 ± 0.321
1.931TrpThr: 1.931 ± 0.963
1.287TrpVal: 1.287 ± 0.278
0.644TrpTrp: 0.644 ± 0.321
0.644TrpTyr: 0.644 ± 0.599
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.931TyrAla: 1.931 ± 1.796
0.644TyrCys: 0.644 ± 0.321
0.644TyrAsp: 0.644 ± 0.599
5.148TyrGlu: 5.148 ± 1.11
2.574TyrPhe: 2.574 ± 0.365
3.218TyrGly: 3.218 ± 0.686
1.287TyrHis: 1.287 ± 0.278
3.218TyrIle: 3.218 ± 0.234
1.287TyrLys: 1.287 ± 0.278
1.287TyrLeu: 1.287 ± 0.278
1.287TyrMet: 1.287 ± 0.642
1.931TyrAsn: 1.931 ± 0.043
0.644TyrPro: 0.644 ± 0.321
0.644TyrGln: 0.644 ± 0.321
1.931TyrArg: 1.931 ± 0.876
1.931TyrSer: 1.931 ± 0.876
2.574TyrThr: 2.574 ± 0.365
3.218TyrVal: 3.218 ± 0.234
0.0TyrTrp: 0.0 ± 0.0
0.644TyrTyr: 0.644 ± 0.321
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.644XaaIle: 0.644 ± 0.321
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1555 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski