Amino acid dipepetide frequency for Rudaeicoccus suwonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.73AlaAla: 19.73 ± 0.183	1.031AlaCys: 1.031 ± 0.033	8.465AlaAsp: 8.465 ± 0.099	6.563AlaGlu: 6.563 ± 0.087	3.413AlaPhe: 3.413 ± 0.057	11.85AlaGly: 11.85 ± 0.119	2.769AlaHis: 2.769 ± 0.057	5.436AlaIle: 5.436 ± 0.074	2.845AlaLys: 2.845 ± 0.065	12.474AlaLeu: 12.474 ± 0.131	2.899AlaMet: 2.899 ± 0.051	2.288AlaAsn: 2.288 ± 0.052	5.876AlaPro: 5.876 ± 0.074	4.37AlaGln: 4.37 ± 0.064	8.393AlaArg: 8.393 ± 0.106	6.912AlaSer: 6.912 ± 0.092	8.354AlaThr: 8.354 ± 0.093	11.01AlaVal: 11.01 ± 0.112	1.713AlaTrp: 1.713 ± 0.052	2.567AlaTyr: 2.567 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.024CysAla: 1.024 ± 0.035	0.11CysCys: 0.11 ± 0.01	0.567CysAsp: 0.567 ± 0.023	0.39CysGlu: 0.39 ± 0.02	0.256CysPhe: 0.256 ± 0.014	0.981CysGly: 0.981 ± 0.031	0.212CysHis: 0.212 ± 0.016	0.298CysIle: 0.298 ± 0.017	0.104CysLys: 0.104 ± 0.01	0.688CysLeu: 0.688 ± 0.024	0.146CysMet: 0.146 ± 0.01	0.17CysAsn: 0.17 ± 0.012	0.462CysPro: 0.462 ± 0.021	0.208CysGln: 0.208 ± 0.014	0.565CysArg: 0.565 ± 0.024	0.494CysSer: 0.494 ± 0.02	0.507CysThr: 0.507 ± 0.022	0.701CysVal: 0.701 ± 0.027	0.14CysTrp: 0.14 ± 0.011	0.167CysTyr: 0.167 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.94AspAla: 7.94 ± 0.091	0.402AspCys: 0.402 ± 0.019	4.505AspAsp: 4.505 ± 0.07	4.098AspGlu: 4.098 ± 0.073	1.685AspPhe: 1.685 ± 0.041	5.906AspGly: 5.906 ± 0.075	1.597AspHis: 1.597 ± 0.041	2.367AspIle: 2.367 ± 0.054	1.272AspLys: 1.272 ± 0.04	6.63AspLeu: 6.63 ± 0.084	0.95AspMet: 0.95 ± 0.026	1.228AspAsn: 1.228 ± 0.037	4.063AspPro: 4.063 ± 0.07	1.99AspGln: 1.99 ± 0.045	4.5AspArg: 4.5 ± 0.078	3.084AspSer: 3.084 ± 0.048	2.994AspThr: 2.994 ± 0.053	5.546AspVal: 5.546 ± 0.068	0.966AspTrp: 0.966 ± 0.032	1.283AspTyr: 1.283 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	5.893GluAla: 5.893 ± 0.075	0.372GluCys: 0.372 ± 0.017	2.341GluAsp: 2.341 ± 0.048	2.189GluGlu: 2.189 ± 0.046	1.549GluPhe: 1.549 ± 0.038	3.379GluGly: 3.379 ± 0.057	1.567GluHis: 1.567 ± 0.04	2.379GluIle: 2.379 ± 0.046	1.117GluLys: 1.117 ± 0.04	5.871GluLeu: 5.871 ± 0.081	0.956GluMet: 0.956 ± 0.034	0.911GluAsn: 0.911 ± 0.028	2.71GluPro: 2.71 ± 0.047	2.457GluGln: 2.457 ± 0.05	4.53GluArg: 4.53 ± 0.078	2.805GluSer: 2.805 ± 0.057	2.598GluThr: 2.598 ± 0.055	4.28GluVal: 4.28 ± 0.071	0.754GluTrp: 0.754 ± 0.025	0.874GluTyr: 0.874 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.885PheAla: 3.885 ± 0.059	0.316PheCys: 0.316 ± 0.02	2.121PheAsp: 2.121 ± 0.05	1.551PheGlu: 1.551 ± 0.038	0.939PhePhe: 0.939 ± 0.034	3.272PheGly: 3.272 ± 0.061	0.631PheHis: 0.631 ± 0.021	1.05PheIle: 1.05 ± 0.036	0.523PheLys: 0.523 ± 0.022	2.372PheLeu: 2.372 ± 0.045	0.466PheMet: 0.466 ± 0.027	0.735PheAsn: 0.735 ± 0.033	1.279PhePro: 1.279 ± 0.04	0.693PheGln: 0.693 ± 0.021	1.6PheArg: 1.6 ± 0.036	1.65PheSer: 1.65 ± 0.037	1.926PheThr: 1.926 ± 0.04	2.748PheVal: 2.748 ± 0.057	0.457PheTrp: 0.457 ± 0.022	0.62PheTyr: 0.62 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.951GlyAla: 9.951 ± 0.101	0.849GlyCys: 0.849 ± 0.028	5.046GlyAsp: 5.046 ± 0.064	4.282GlyGlu: 4.282 ± 0.066	3.032GlyPhe: 3.032 ± 0.055	7.857GlyGly: 7.857 ± 0.108	2.137GlyHis: 2.137 ± 0.052	4.055GlyIle: 4.055 ± 0.071	2.31GlyLys: 2.31 ± 0.058	8.563GlyLeu: 8.563 ± 0.087	2.141GlyMet: 2.141 ± 0.051	1.95GlyAsn: 1.95 ± 0.051	3.853GlyPro: 3.853 ± 0.055	2.972GlyGln: 2.972 ± 0.065	6.357GlyArg: 6.357 ± 0.081	6.051GlySer: 6.051 ± 0.087	5.475GlyThr: 5.475 ± 0.091	7.733GlyVal: 7.733 ± 0.086	1.67GlyTrp: 1.67 ± 0.039	2.297GlyTyr: 2.297 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.578HisAla: 2.578 ± 0.056	0.223HisCys: 0.223 ± 0.013	1.605HisAsp: 1.605 ± 0.036	1.295HisGlu: 1.295 ± 0.037	0.675HisPhe: 0.675 ± 0.025	2.188HisGly: 2.188 ± 0.05	0.775HisHis: 0.775 ± 0.03	0.822HisIle: 0.822 ± 0.031	0.36HisLys: 0.36 ± 0.019	2.442HisLeu: 2.442 ± 0.047	0.362HisMet: 0.362 ± 0.016	0.461HisAsn: 0.461 ± 0.02	1.572HisPro: 1.572 ± 0.043	0.737HisGln: 0.737 ± 0.032	1.872HisArg: 1.872 ± 0.043	1.197HisSer: 1.197 ± 0.037	1.429HisThr: 1.429 ± 0.035	1.95HisVal: 1.95 ± 0.042	0.352HisTrp: 0.352 ± 0.015	0.456HisTyr: 0.456 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.204IleAla: 6.204 ± 0.079	0.416IleCys: 0.416 ± 0.02	3.307IleAsp: 3.307 ± 0.05	2.493IleGlu: 2.493 ± 0.052	1.16IlePhe: 1.16 ± 0.033	4.384IleGly: 4.384 ± 0.077	0.77IleHis: 0.77 ± 0.026	1.41IleIle: 1.41 ± 0.04	0.824IleLys: 0.824 ± 0.029	3.015IleLeu: 3.015 ± 0.05	0.555IleMet: 0.555 ± 0.021	1.027IleAsn: 1.027 ± 0.036	2.174IlePro: 2.174 ± 0.041	1.009IleGln: 1.009 ± 0.038	2.683IleArg: 2.683 ± 0.049	2.416IleSer: 2.416 ± 0.054	2.853IleThr: 2.853 ± 0.06	3.982IleVal: 3.982 ± 0.062	0.544IleTrp: 0.544 ± 0.022	0.76IleTyr: 0.76 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.656LysAla: 2.656 ± 0.058	0.105LysCys: 0.105 ± 0.009	1.179LysAsp: 1.179 ± 0.039	0.915LysGlu: 0.915 ± 0.033	0.556LysPhe: 0.556 ± 0.028	1.677LysGly: 1.677 ± 0.047	0.476LysHis: 0.476 ± 0.021	0.918LysIle: 0.918 ± 0.031	0.766LysLys: 0.766 ± 0.044	1.877LysLeu: 1.877 ± 0.045	0.438LysMet: 0.438 ± 0.022	0.512LysAsn: 0.512 ± 0.021	1.284LysPro: 1.284 ± 0.037	0.804LysGln: 0.804 ± 0.029	1.429LysArg: 1.429 ± 0.046	1.317LysSer: 1.317 ± 0.036	1.385LysThr: 1.385 ± 0.041	2.004LysVal: 2.004 ± 0.04	0.285LysTrp: 0.285 ± 0.019	0.486LysTyr: 0.486 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.434LeuAla: 13.434 ± 0.12	0.731LeuCys: 0.731 ± 0.024	6.288LeuAsp: 6.288 ± 0.09	4.206LeuGlu: 4.206 ± 0.062	2.416LeuPhe: 2.416 ± 0.055	8.366LeuGly: 8.366 ± 0.089	2.177LeuHis: 2.177 ± 0.052	4.143LeuIle: 4.143 ± 0.072	1.818LeuLys: 1.818 ± 0.051	9.736LeuLeu: 9.736 ± 0.119	1.82LeuMet: 1.82 ± 0.041	1.883LeuAsn: 1.883 ± 0.039	5.693LeuPro: 5.693 ± 0.073	3.149LeuGln: 3.149 ± 0.05	7.651LeuArg: 7.651 ± 0.102	5.729LeuSer: 5.729 ± 0.078	6.599LeuThr: 6.599 ± 0.07	8.775LeuVal: 8.775 ± 0.116	1.225LeuTrp: 1.225 ± 0.035	1.55LeuTyr: 1.55 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.433MetAla: 2.433 ± 0.049	0.182MetCys: 0.182 ± 0.012	0.846MetAsp: 0.846 ± 0.03	0.706MetGlu: 0.706 ± 0.026	0.606MetPhe: 0.606 ± 0.029	1.38MetGly: 1.38 ± 0.037	0.424MetHis: 0.424 ± 0.018	0.814MetIle: 0.814 ± 0.028	0.45MetLys: 0.45 ± 0.021	1.946MetLeu: 1.946 ± 0.044	0.365MetMet: 0.365 ± 0.02	0.492MetAsn: 0.492 ± 0.02	1.285MetPro: 1.285 ± 0.033	0.644MetGln: 0.644 ± 0.025	1.497MetArg: 1.497 ± 0.03	1.837MetSer: 1.837 ± 0.043	2.058MetThr: 2.058 ± 0.035	1.546MetVal: 1.546 ± 0.039	0.265MetTrp: 0.265 ± 0.019	0.325MetTyr: 0.325 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.551AsnAla: 2.551 ± 0.069	0.181AsnCys: 0.181 ± 0.013	1.264AsnAsp: 1.264 ± 0.033	0.868AsnGlu: 0.868 ± 0.028	0.559AsnPhe: 0.559 ± 0.025	2.032AsnGly: 2.032 ± 0.055	0.455AsnHis: 0.455 ± 0.019	0.823AsnIle: 0.823 ± 0.031	0.484AsnLys: 0.484 ± 0.022	1.985AsnLeu: 1.985 ± 0.05	0.347AsnMet: 0.347 ± 0.018	0.588AsnAsn: 0.588 ± 0.026	1.649AsnPro: 1.649 ± 0.039	0.692AsnGln: 0.692 ± 0.028	1.272AsnArg: 1.272 ± 0.038	1.259AsnSer: 1.259 ± 0.039	1.217AsnThr: 1.217 ± 0.036	1.728AsnVal: 1.728 ± 0.038	0.344AsnTrp: 0.344 ± 0.016	0.5AsnTyr: 0.5 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.825ProAla: 6.825 ± 0.091	0.289ProCys: 0.289 ± 0.017	3.91ProAsp: 3.91 ± 0.061	3.065ProGlu: 3.065 ± 0.053	1.424ProPhe: 1.424 ± 0.035	5.098ProGly: 5.098 ± 0.075	1.175ProHis: 1.175 ± 0.034	1.926ProIle: 1.926 ± 0.046	1.131ProLys: 1.131 ± 0.036	4.598ProLeu: 4.598 ± 0.061	1.111ProMet: 1.111 ± 0.033	1.125ProAsn: 1.125 ± 0.034	2.48ProPro: 2.48 ± 0.059	1.995ProGln: 1.995 ± 0.054	3.277ProArg: 3.277 ± 0.053	3.33ProSer: 3.33 ± 0.063	3.795ProThr: 3.795 ± 0.068	5.03ProVal: 5.03 ± 0.067	0.926ProTrp: 0.926 ± 0.03	1.118ProTyr: 1.118 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.864GlnAla: 3.864 ± 0.06	0.216GlnCys: 0.216 ± 0.014	1.503GlnAsp: 1.503 ± 0.041	1.388GlnGlu: 1.388 ± 0.037	0.933GlnPhe: 0.933 ± 0.028	2.215GlnGly: 2.215 ± 0.056	0.929GlnHis: 0.929 ± 0.03	1.69GlnIle: 1.69 ± 0.04	0.592GlnLys: 0.592 ± 0.023	3.919GlnLeu: 3.919 ± 0.067	0.727GlnMet: 0.727 ± 0.028	0.654GlnAsn: 0.654 ± 0.028	2.064GlnPro: 2.064 ± 0.056	1.811GlnGln: 1.811 ± 0.056	2.86GlnArg: 2.86 ± 0.059	1.797GlnSer: 1.797 ± 0.041	1.927GlnThr: 1.927 ± 0.046	3.194GlnVal: 3.194 ± 0.053	0.637GlnTrp: 0.637 ± 0.026	0.566GlnTyr: 0.566 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.036ArgAla: 8.036 ± 0.096	0.58ArgCys: 0.58 ± 0.024	4.401ArgAsp: 4.401 ± 0.071	3.978ArgGlu: 3.978 ± 0.072	2.245ArgPhe: 2.245 ± 0.046	5.166ArgGly: 5.166 ± 0.097	1.956ArgHis: 1.956 ± 0.043	3.331ArgIle: 3.331 ± 0.056	1.543ArgLys: 1.543 ± 0.041	7.275ArgLeu: 7.275 ± 0.106	1.814ArgMet: 1.814 ± 0.032	1.435ArgAsn: 1.435 ± 0.038	3.818ArgPro: 3.818 ± 0.059	2.451ArgGln: 2.451 ± 0.054	6.62ArgArg: 6.62 ± 0.114	4.519ArgSer: 4.519 ± 0.077	4.298ArgThr: 4.298 ± 0.073	5.652ArgVal: 5.652 ± 0.07	1.323ArgTrp: 1.323 ± 0.036	1.487ArgTyr: 1.487 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.789SerAla: 7.789 ± 0.101	0.443SerCys: 0.443 ± 0.024	3.436SerAsp: 3.436 ± 0.06	2.63SerGlu: 2.63 ± 0.048	1.829SerPhe: 1.829 ± 0.046	6.357SerGly: 6.357 ± 0.103	1.234SerHis: 1.234 ± 0.032	2.409SerIle: 2.409 ± 0.046	1.192SerLys: 1.192 ± 0.031	5.327SerLeu: 5.327 ± 0.075	1.469SerMet: 1.469 ± 0.037	1.295SerAsn: 1.295 ± 0.038	3.162SerPro: 3.162 ± 0.062	1.773SerGln: 1.773 ± 0.044	3.956SerArg: 3.956 ± 0.063	4.163SerSer: 4.163 ± 0.102	4.133SerThr: 4.133 ± 0.076	4.955SerVal: 4.955 ± 0.073	1.053SerTrp: 1.053 ± 0.028	1.449SerTyr: 1.449 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	8.288ThrAla: 8.288 ± 0.106	0.516ThrCys: 0.516 ± 0.021	4.076ThrAsp: 4.076 ± 0.069	2.826ThrGlu: 2.826 ± 0.048	1.912ThrPhe: 1.912 ± 0.044	6.277ThrGly: 6.277 ± 0.07	1.287ThrHis: 1.287 ± 0.032	2.727ThrIle: 2.727 ± 0.059	1.381ThrLys: 1.381 ± 0.041	5.618ThrLeu: 5.618 ± 0.081	1.193ThrMet: 1.193 ± 0.033	1.357ThrAsn: 1.357 ± 0.038	3.874ThrPro: 3.874 ± 0.07	1.869ThrGln: 1.869 ± 0.04	3.845ThrArg: 3.845 ± 0.059	4.212ThrSer: 4.212 ± 0.074	4.853ThrThr: 4.853 ± 0.099	5.817ThrVal: 5.817 ± 0.077	1.066ThrTrp: 1.066 ± 0.036	1.532ThrTyr: 1.532 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	11.665ValAla: 11.665 ± 0.127	0.823ValCys: 0.823 ± 0.03	5.733ValAsp: 5.733 ± 0.077	4.535ValGlu: 4.535 ± 0.07	2.438ValPhe: 2.438 ± 0.05	7.138ValGly: 7.138 ± 0.078	1.962ValHis: 1.962 ± 0.047	4.112ValIle: 4.112 ± 0.07	1.657ValLys: 1.657 ± 0.043	9.067ValLeu: 9.067 ± 0.111	1.786ValMet: 1.786 ± 0.04	1.762ValAsn: 1.762 ± 0.041	4.47ValPro: 4.47 ± 0.059	2.55ValGln: 2.55 ± 0.052	6.197ValArg: 6.197 ± 0.086	5.026ValSer: 5.026 ± 0.073	6.124ValThr: 6.124 ± 0.094	9.085ValVal: 9.085 ± 0.115	1.225ValTrp: 1.225 ± 0.035	1.383ValTyr: 1.383 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.611TrpAla: 1.611 ± 0.042	0.217TrpCys: 0.217 ± 0.016	0.794TrpAsp: 0.794 ± 0.025	0.576TrpGlu: 0.576 ± 0.023	0.529TrpPhe: 0.529 ± 0.023	1.079TrpGly: 1.079 ± 0.035	0.459TrpHis: 0.459 ± 0.024	0.661TrpIle: 0.661 ± 0.024	0.301TrpLys: 0.301 ± 0.016	1.858TrpLeu: 1.858 ± 0.047	0.341TrpMet: 0.341 ± 0.019	0.429TrpAsn: 0.429 ± 0.023	0.817TrpPro: 0.817 ± 0.027	0.707TrpGln: 0.707 ± 0.023	1.361TrpArg: 1.361 ± 0.038	1.148TrpSer: 1.148 ± 0.034	0.937TrpThr: 0.937 ± 0.029	1.187TrpVal: 1.187 ± 0.033	0.423TrpTrp: 0.423 ± 0.023	0.259TrpTyr: 0.259 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.601TyrAla: 2.601 ± 0.052	0.191TyrCys: 0.191 ± 0.012	1.615TyrAsp: 1.615 ± 0.051	0.979TyrGlu: 0.979 ± 0.029	0.679TyrPhe: 0.679 ± 0.027	1.981TyrGly: 1.981 ± 0.05	0.357TyrHis: 0.357 ± 0.016	0.616TyrIle: 0.616 ± 0.024	0.398TyrLys: 0.398 ± 0.018	2.127TyrLeu: 2.127 ± 0.04	0.211TyrMet: 0.211 ± 0.015	0.499TyrAsn: 0.499 ± 0.028	1.043TyrPro: 1.043 ± 0.03	0.604TyrGln: 0.604 ± 0.029	1.463TyrArg: 1.463 ± 0.037	1.108TyrSer: 1.108 ± 0.038	1.065TyrThr: 1.065 ± 0.035	1.815TyrVal: 1.815 ± 0.036	0.327TyrTrp: 0.327 ± 0.015	0.473TyrTyr: 0.473 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3440 proteins (1140410 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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