Amino acid dipepetide frequency for Botryotinia calthae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.079AlaAla: 7.079 ± 0.053	0.934AlaCys: 0.934 ± 0.014	3.595AlaAsp: 3.595 ± 0.028	4.678AlaGlu: 4.678 ± 0.04	2.87AlaPhe: 2.87 ± 0.025	5.073AlaGly: 5.073 ± 0.038	1.54AlaHis: 1.54 ± 0.015	4.374AlaIle: 4.374 ± 0.029	4.118AlaLys: 4.118 ± 0.031	6.746AlaLeu: 6.746 ± 0.043	1.832AlaMet: 1.832 ± 0.02	3.043AlaAsn: 3.043 ± 0.024	4.194AlaPro: 4.194 ± 0.036	3.026AlaGln: 3.026 ± 0.028	4.061AlaArg: 4.061 ± 0.033	6.79AlaSer: 6.79 ± 0.045	4.927AlaThr: 4.927 ± 0.037	4.457AlaVal: 4.457 ± 0.032	0.988AlaTrp: 0.988 ± 0.016	2.02AlaTyr: 2.02 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.846CysAla: 0.846 ± 0.013	0.236CysCys: 0.236 ± 0.008	0.641CysAsp: 0.641 ± 0.011	0.634CysGlu: 0.634 ± 0.013	0.538CysPhe: 0.538 ± 0.01	0.932CysGly: 0.932 ± 0.015	0.294CysHis: 0.294 ± 0.007	0.721CysIle: 0.721 ± 0.012	0.581CysLys: 0.581 ± 0.013	1.16CysLeu: 1.16 ± 0.016	0.284CysMet: 0.284 ± 0.008	0.472CysAsn: 0.472 ± 0.009	0.63CysPro: 0.63 ± 0.013	0.419CysGln: 0.419 ± 0.009	0.645CysArg: 0.645 ± 0.011	0.926CysSer: 0.926 ± 0.015	0.7CysThr: 0.7 ± 0.012	0.737CysVal: 0.737 ± 0.011	0.188CysTrp: 0.188 ± 0.006	0.354CysTyr: 0.354 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.063AspAla: 4.063 ± 0.028	0.632AspCys: 0.632 ± 0.013	4.104AspAsp: 4.104 ± 0.041	4.627AspGlu: 4.627 ± 0.04	2.25AspPhe: 2.25 ± 0.021	3.873AspGly: 3.873 ± 0.03	1.164AspHis: 1.164 ± 0.014	3.386AspIle: 3.386 ± 0.028	2.451AspLys: 2.451 ± 0.026	4.916AspLeu: 4.916 ± 0.034	1.26AspMet: 1.26 ± 0.015	2.138AspAsn: 2.138 ± 0.02	2.929AspPro: 2.929 ± 0.026	1.771AspGln: 1.771 ± 0.019	2.746AspArg: 2.746 ± 0.032	4.337AspSer: 4.337 ± 0.031	3.02AspThr: 3.02 ± 0.025	3.431AspVal: 3.431 ± 0.027	0.863AspTrp: 0.863 ± 0.013	1.63AspTyr: 1.63 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.914GluAla: 4.914 ± 0.036	0.645GluCys: 0.645 ± 0.014	4.428GluAsp: 4.428 ± 0.037	6.237GluGlu: 6.237 ± 0.06	2.106GluPhe: 2.106 ± 0.021	4.0GluGly: 4.0 ± 0.033	1.328GluHis: 1.328 ± 0.014	3.799GluIle: 3.799 ± 0.028	4.519GluLys: 4.519 ± 0.039	5.202GluLeu: 5.202 ± 0.038	1.664GluMet: 1.664 ± 0.018	2.971GluAsn: 2.971 ± 0.024	2.581GluPro: 2.581 ± 0.029	2.359GluGln: 2.359 ± 0.028	4.019GluArg: 4.019 ± 0.044	4.8GluSer: 4.8 ± 0.039	3.554GluThr: 3.554 ± 0.028	3.751GluVal: 3.751 ± 0.027	0.918GluTrp: 0.918 ± 0.014	1.788GluTyr: 1.788 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.814PheAla: 2.814 ± 0.027	0.557PheCys: 0.557 ± 0.01	2.299PheAsp: 2.299 ± 0.021	2.342PheGlu: 2.342 ± 0.021	1.57PhePhe: 1.57 ± 0.019	2.887PheGly: 2.887 ± 0.027	0.893PheHis: 0.893 ± 0.013	1.945PheIle: 1.945 ± 0.019	1.726PheLys: 1.726 ± 0.02	3.423PheLeu: 3.423 ± 0.029	0.831PheMet: 0.831 ± 0.012	1.613PheAsn: 1.613 ± 0.018	1.964PhePro: 1.964 ± 0.018	1.428PheGln: 1.428 ± 0.018	1.826PheArg: 1.826 ± 0.017	3.163PheSer: 3.163 ± 0.027	2.277PheThr: 2.277 ± 0.025	2.274PheVal: 2.274 ± 0.023	0.633PheTrp: 0.633 ± 0.011	1.115PheTyr: 1.115 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.651GlyAla: 4.651 ± 0.038	0.835GlyCys: 0.835 ± 0.014	3.479GlyAsp: 3.479 ± 0.026	3.92GlyGlu: 3.92 ± 0.031	2.773GlyPhe: 2.773 ± 0.027	5.733GlyGly: 5.733 ± 0.054	1.543GlyHis: 1.543 ± 0.02	3.782GlyIle: 3.782 ± 0.028	3.93GlyLys: 3.93 ± 0.035	5.685GlyLeu: 5.685 ± 0.037	1.708GlyMet: 1.708 ± 0.02	2.961GlyAsn: 2.961 ± 0.031	2.901GlyPro: 2.901 ± 0.03	2.268GlyGln: 2.268 ± 0.024	3.769GlyArg: 3.769 ± 0.029	5.763GlySer: 5.763 ± 0.043	3.987GlyThr: 3.987 ± 0.033	4.16GlyVal: 4.16 ± 0.03	1.127GlyTrp: 1.127 ± 0.016	2.177GlyTyr: 2.177 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.555HisAla: 1.555 ± 0.02	0.311HisCys: 0.311 ± 0.008	1.244HisAsp: 1.244 ± 0.016	1.336HisGlu: 1.336 ± 0.016	0.908HisPhe: 0.908 ± 0.013	1.554HisGly: 1.554 ± 0.018	0.762HisHis: 0.762 ± 0.014	1.261HisIle: 1.261 ± 0.015	1.023HisLys: 1.023 ± 0.014	2.045HisLeu: 2.045 ± 0.022	0.485HisMet: 0.485 ± 0.009	0.969HisAsn: 0.969 ± 0.015	1.488HisPro: 1.488 ± 0.016	0.974HisGln: 0.974 ± 0.015	1.336HisArg: 1.336 ± 0.017	1.916HisSer: 1.916 ± 0.02	1.323HisThr: 1.323 ± 0.017	1.252HisVal: 1.252 ± 0.015	0.302HisTrp: 0.302 ± 0.008	0.692HisTyr: 0.692 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.304IleAla: 4.304 ± 0.032	0.804IleCys: 0.804 ± 0.013	3.22IleAsp: 3.22 ± 0.027	3.497IleGlu: 3.497 ± 0.028	2.273IlePhe: 2.273 ± 0.022	3.473IleGly: 3.473 ± 0.028	1.297IleHis: 1.297 ± 0.015	3.126IleIle: 3.126 ± 0.029	2.74IleLys: 2.74 ± 0.022	5.052IleLeu: 5.052 ± 0.035	1.159IleMet: 1.159 ± 0.014	2.278IleAsn: 2.278 ± 0.021	3.498IlePro: 3.498 ± 0.025	2.116IleGln: 2.116 ± 0.022	2.817IleArg: 2.817 ± 0.025	4.836IleSer: 4.836 ± 0.033	3.35IleThr: 3.35 ± 0.031	3.375IleVal: 3.375 ± 0.028	0.79IleTrp: 0.79 ± 0.015	1.612IleTyr: 1.612 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.283LysAla: 4.283 ± 0.032	0.586LysCys: 0.586 ± 0.011	3.148LysAsp: 3.148 ± 0.028	4.142LysGlu: 4.142 ± 0.041	1.774LysPhe: 1.774 ± 0.019	3.288LysGly: 3.288 ± 0.03	1.185LysHis: 1.185 ± 0.016	2.993LysIle: 2.993 ± 0.023	4.131LysLys: 4.131 ± 0.044	4.451LysLeu: 4.451 ± 0.029	1.196LysMet: 1.196 ± 0.016	2.32LysAsn: 2.32 ± 0.021	2.788LysPro: 2.788 ± 0.028	1.895LysGln: 1.895 ± 0.021	3.585LysArg: 3.585 ± 0.034	4.44LysSer: 4.44 ± 0.034	3.181LysThr: 3.181 ± 0.029	3.128LysVal: 3.128 ± 0.026	0.746LysTrp: 0.746 ± 0.012	1.552LysTyr: 1.552 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	6.789LeuAla: 6.789 ± 0.041	1.133LeuCys: 1.133 ± 0.016	4.823LeuAsp: 4.823 ± 0.029	5.65LeuGlu: 5.65 ± 0.045	3.203LeuPhe: 3.203 ± 0.029	5.552LeuGly: 5.552 ± 0.039	2.045LeuHis: 2.045 ± 0.024	4.24LeuIle: 4.24 ± 0.033	4.682LeuLys: 4.682 ± 0.041	7.772LeuLeu: 7.772 ± 0.056	1.792LeuMet: 1.792 ± 0.02	3.508LeuAsn: 3.508 ± 0.026	5.228LeuPro: 5.228 ± 0.035	3.701LeuGln: 3.701 ± 0.033	5.083LeuArg: 5.083 ± 0.039	7.343LeuSer: 7.343 ± 0.042	4.76LeuThr: 4.76 ± 0.029	4.851LeuVal: 4.851 ± 0.037	1.125LeuTrp: 1.125 ± 0.016	2.297LeuTyr: 2.297 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.052MetAla: 2.052 ± 0.018	0.244MetCys: 0.244 ± 0.007	1.305MetAsp: 1.305 ± 0.018	1.498MetGlu: 1.498 ± 0.02	0.768MetPhe: 0.768 ± 0.014	1.575MetGly: 1.575 ± 0.018	0.471MetHis: 0.471 ± 0.01	1.179MetIle: 1.179 ± 0.015	1.229MetLys: 1.229 ± 0.016	1.748MetLeu: 1.748 ± 0.019	0.618MetMet: 0.618 ± 0.012	0.998MetAsn: 0.998 ± 0.015	1.192MetPro: 1.192 ± 0.014	0.856MetGln: 0.856 ± 0.015	1.235MetArg: 1.235 ± 0.016	2.016MetSer: 2.016 ± 0.017	1.307MetThr: 1.307 ± 0.017	1.305MetVal: 1.305 ± 0.017	0.258MetTrp: 0.258 ± 0.007	0.545MetTyr: 0.545 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.236AsnAla: 3.236 ± 0.022	0.503AsnCys: 0.503 ± 0.009	2.311AsnAsp: 2.311 ± 0.024	2.504AsnGlu: 2.504 ± 0.026	1.674AsnPhe: 1.674 ± 0.017	3.414AsnGly: 3.414 ± 0.035	1.049AsnHis: 1.049 ± 0.014	2.565AsnIle: 2.565 ± 0.022	1.929AsnLys: 1.929 ± 0.018	3.711AsnLeu: 3.711 ± 0.028	0.967AsnMet: 0.967 ± 0.014	2.009AsnAsn: 2.009 ± 0.024	2.642AsnPro: 2.642 ± 0.027	1.596AsnGln: 1.596 ± 0.019	2.091AsnArg: 2.091 ± 0.022	3.691AsnSer: 3.691 ± 0.03	2.754AsnThr: 2.754 ± 0.025	2.456AsnVal: 2.456 ± 0.022	0.598AsnTrp: 0.598 ± 0.011	1.261AsnTyr: 1.261 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.285ProAla: 4.285 ± 0.029	0.456ProCys: 0.456 ± 0.01	2.763ProAsp: 2.763 ± 0.023	3.588ProGlu: 3.588 ± 0.028	1.964ProPhe: 1.964 ± 0.021	3.41ProGly: 3.41 ± 0.031	1.24ProHis: 1.24 ± 0.016	3.013ProIle: 3.013 ± 0.026	2.918ProLys: 2.918 ± 0.025	4.517ProLeu: 4.517 ± 0.03	1.048ProMet: 1.048 ± 0.015	2.44ProAsn: 2.44 ± 0.024	4.555ProPro: 4.555 ± 0.058	2.423ProGln: 2.423 ± 0.031	3.1ProArg: 3.1 ± 0.029	6.015ProSer: 6.015 ± 0.049	4.045ProThr: 4.045 ± 0.032	3.197ProVal: 3.197 ± 0.031	0.642ProTrp: 0.642 ± 0.012	1.519ProTyr: 1.519 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.044GlnAla: 3.044 ± 0.029	0.414GlnCys: 0.414 ± 0.007	1.972GlnAsp: 1.972 ± 0.02	2.443GlnGlu: 2.443 ± 0.026	1.332GlnPhe: 1.332 ± 0.016	2.189GlnGly: 2.189 ± 0.024	0.977GlnHis: 0.977 ± 0.016	2.135GlnIle: 2.135 ± 0.018	2.259GlnLys: 2.259 ± 0.023	3.139GlnLeu: 3.139 ± 0.027	0.897GlnMet: 0.897 ± 0.014	1.901GlnAsn: 1.901 ± 0.02	2.17GlnPro: 2.17 ± 0.027	2.178GlnGln: 2.178 ± 0.041	2.345GlnArg: 2.345 ± 0.023	3.308GlnSer: 3.308 ± 0.031	2.317GlnThr: 2.317 ± 0.022	2.02GlnVal: 2.02 ± 0.022	0.535GlnTrp: 0.535 ± 0.009	1.211GlnTyr: 1.211 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	3.896ArgAla: 3.896 ± 0.029	0.63ArgCys: 0.63 ± 0.011	3.08ArgAsp: 3.08 ± 0.034	3.926ArgGlu: 3.926 ± 0.041	1.949ArgPhe: 1.949 ± 0.02	3.6ArgGly: 3.6 ± 0.032	1.311ArgHis: 1.311 ± 0.018	2.983ArgIle: 2.983 ± 0.024	3.723ArgLys: 3.723 ± 0.032	4.665ArgLeu: 4.665 ± 0.033	1.274ArgMet: 1.274 ± 0.015	2.527ArgAsn: 2.527 ± 0.024	2.972ArgPro: 2.972 ± 0.027	2.27ArgGln: 2.27 ± 0.022	4.383ArgArg: 4.383 ± 0.044	4.649ArgSer: 4.649 ± 0.038	3.022ArgThr: 3.022 ± 0.026	2.947ArgVal: 2.947 ± 0.023	0.793ArgTrp: 0.793 ± 0.013	1.568ArgTyr: 1.568 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.287SerAla: 6.287 ± 0.048	0.9SerCys: 0.9 ± 0.013	4.369SerAsp: 4.369 ± 0.033	4.668SerGlu: 4.668 ± 0.03	3.217SerPhe: 3.217 ± 0.028	5.652SerGly: 5.652 ± 0.045	2.055SerHis: 2.055 ± 0.023	4.974SerIle: 4.974 ± 0.038	4.513SerLys: 4.513 ± 0.037	7.279SerLeu: 7.279 ± 0.046	1.836SerMet: 1.836 ± 0.02	3.899SerAsn: 3.899 ± 0.028	5.661SerPro: 5.661 ± 0.053	3.493SerGln: 3.493 ± 0.028	4.868SerArg: 4.868 ± 0.037	10.138SerSer: 10.138 ± 0.095	6.463SerThr: 6.463 ± 0.053	4.478SerVal: 4.478 ± 0.032	1.08SerTrp: 1.08 ± 0.012	2.308SerTyr: 2.308 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.72ThrAla: 4.72 ± 0.037	0.754ThrCys: 0.754 ± 0.014	2.771ThrAsp: 2.771 ± 0.025	3.279ThrGlu: 3.279 ± 0.023	2.373ThrPhe: 2.373 ± 0.023	4.09ThrGly: 4.09 ± 0.031	1.312ThrHis: 1.312 ± 0.016	3.705ThrIle: 3.705 ± 0.029	3.046ThrLys: 3.046 ± 0.027	5.227ThrLeu: 5.227 ± 0.036	1.244ThrMet: 1.244 ± 0.015	2.59ThrAsn: 2.59 ± 0.022	4.487ThrPro: 4.487 ± 0.036	2.197ThrGln: 2.197 ± 0.023	2.967ThrArg: 2.967 ± 0.027	6.241ThrSer: 6.241 ± 0.051	4.72ThrThr: 4.72 ± 0.053	3.455ThrVal: 3.455 ± 0.029	0.796ThrTrp: 0.796 ± 0.013	1.716ThrTyr: 1.716 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.572ValAla: 4.572 ± 0.03	0.738ValCys: 0.738 ± 0.012	3.476ValAsp: 3.476 ± 0.028	4.041ValGlu: 4.041 ± 0.032	2.295ValPhe: 2.295 ± 0.026	3.844ValGly: 3.844 ± 0.034	1.231ValHis: 1.231 ± 0.014	3.074ValIle: 3.074 ± 0.027	3.121ValLys: 3.121 ± 0.03	5.04ValLeu: 5.04 ± 0.034	1.302ValMet: 1.302 ± 0.016	2.302ValAsn: 2.302 ± 0.021	3.21ValPro: 3.21 ± 0.027	2.146ValGln: 2.146 ± 0.022	2.952ValArg: 2.952 ± 0.026	4.515ValSer: 4.515 ± 0.031	3.339ValThr: 3.339 ± 0.025	3.915ValVal: 3.915 ± 0.032	0.8ValTrp: 0.8 ± 0.013	1.621ValTyr: 1.621 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.953TrpAla: 0.953 ± 0.014	0.196TrpCys: 0.196 ± 0.006	0.853TrpAsp: 0.853 ± 0.014	0.903TrpGlu: 0.903 ± 0.013	0.513TrpPhe: 0.513 ± 0.01	0.94TrpGly: 0.94 ± 0.014	0.315TrpHis: 0.315 ± 0.007	0.807TrpIle: 0.807 ± 0.012	0.884TrpLys: 0.884 ± 0.012	1.21TrpLeu: 1.21 ± 0.016	0.377TrpMet: 0.377 ± 0.008	0.695TrpAsn: 0.695 ± 0.011	0.534TrpPro: 0.534 ± 0.012	0.512TrpGln: 0.512 ± 0.009	0.821TrpArg: 0.821 ± 0.012	1.022TrpSer: 1.022 ± 0.014	0.864TrpThr: 0.864 ± 0.012	0.81TrpVal: 0.81 ± 0.013	0.259TrpTrp: 0.259 ± 0.007	0.414TrpTyr: 0.414 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.999TyrAla: 1.999 ± 0.019	0.431TyrCys: 0.431 ± 0.01	1.707TyrAsp: 1.707 ± 0.021	1.672TyrGlu: 1.672 ± 0.02	1.23TyrPhe: 1.23 ± 0.016	2.074TyrGly: 2.074 ± 0.022	0.725TyrHis: 0.725 ± 0.012	1.557TyrIle: 1.557 ± 0.017	1.29TyrLys: 1.29 ± 0.014	2.591TyrLeu: 2.591 ± 0.026	0.627TyrMet: 0.627 ± 0.011	1.325TyrAsn: 1.325 ± 0.017	1.517TyrPro: 1.517 ± 0.018	1.156TyrGln: 1.156 ± 0.017	1.518TyrArg: 1.518 ± 0.017	2.227TyrSer: 2.227 ± 0.018	1.779TyrThr: 1.779 ± 0.019	1.537TyrVal: 1.537 ± 0.019	0.437TyrTrp: 0.437 ± 0.01	0.982TyrTyr: 0.982 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12263 proteins (5604297 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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