Petromyzon marinus (Sea lamprey)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Cyclostomata; Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon

Average proteome isoelectric point is 6.78

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11407 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|S4RPW3|S4RPW3_PETMA Isoform of S4RPV9 BRF1 RNA polymerase III transcription initiation factor subunit OS=Petromyzon marinus OX=7757 PE=4 SV=1
TT1 pKa = 7.43ALLGNDD7 pKa = 3.15NVYY10 pKa = 10.78EE11 pKa = 4.16LNLDD15 pKa = 3.86YY16 pKa = 11.39NQLQTLSAGVFDD28 pKa = 6.15DD29 pKa = 3.79LTEE32 pKa = 4.7LGTLGLANNQLASLPLGVFADD53 pKa = 4.79LAPTDD58 pKa = 4.62DD59 pKa = 5.16LYY61 pKa = 12.08LNINQLKK68 pKa = 9.37SLPSGVFDD76 pKa = 4.87SLTKK80 pKa = 9.99LTILQLDD87 pKa = 4.13YY88 pKa = 11.43NQLQSVPHH96 pKa = 6.1GAFDD100 pKa = 5.0RR101 pKa = 11.84LTNLQTMQLHH111 pKa = 6.26SDD113 pKa = 3.84VLQSVPNGAFNALTKK128 pKa = 10.88LEE130 pKa = 4.56TITLNVNVWDD140 pKa = 4.88CSSCDD145 pKa = 3.21ILYY148 pKa = 10.69LSEE151 pKa = 4.02

Molecular weight:
16.52 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|S4RWB8|S4RWB8_PETMA RNA-binding motif protein 42 OS=Petromyzon marinus OX=7757 PE=3 SV=1
PP1 pKa = 7.3SPLDD5 pKa = 3.43SSEE8 pKa = 3.94AATAQRR14 pKa = 11.84AKK16 pKa = 10.45FADD19 pKa = 3.92SSSSTLFTSMAALNHH34 pKa = 6.51YY35 pKa = 7.63DD36 pKa = 3.53THH38 pKa = 7.6CNGYY42 pKa = 8.44HH43 pKa = 6.46CKK45 pKa = 10.2HH46 pKa = 5.26VVRR49 pKa = 11.84LISRR53 pKa = 11.84HH54 pKa = 5.18LIARR58 pKa = 11.84KK59 pKa = 9.57VNVVRR64 pKa = 11.84LIIRR68 pKa = 11.84HH69 pKa = 5.17LNARR73 pKa = 11.84KK74 pKa = 9.83VNVVRR79 pKa = 11.84LIIRR83 pKa = 11.84HH84 pKa = 5.91LIARR88 pKa = 11.84KK89 pKa = 9.27VNVVRR94 pKa = 11.84LISRR98 pKa = 11.84HH99 pKa = 5.18LIARR103 pKa = 11.84KK104 pKa = 9.57VNVVRR109 pKa = 11.84LIIRR113 pKa = 11.84HH114 pKa = 5.91LIARR118 pKa = 11.84KK119 pKa = 9.27VNVVRR124 pKa = 11.84LIIRR128 pKa = 11.84HH129 pKa = 5.91LIARR133 pKa = 11.84KK134 pKa = 9.37VNMVRR139 pKa = 11.84LISRR143 pKa = 11.84HH144 pKa = 5.17LIARR148 pKa = 11.84KK149 pKa = 9.57VNVVRR154 pKa = 11.84LIIRR158 pKa = 11.84HH159 pKa = 5.17LNARR163 pKa = 11.84KK164 pKa = 9.83VNVVRR169 pKa = 11.84LIIRR173 pKa = 11.84HH174 pKa = 5.24LNARR178 pKa = 11.84KK179 pKa = 9.21HH180 pKa = 5.65LIARR184 pKa = 11.84KK185 pKa = 8.92VNVVRR190 pKa = 11.84LIIRR194 pKa = 11.84HH195 pKa = 5.17LNARR199 pKa = 11.84KK200 pKa = 9.83VNVVRR205 pKa = 11.84LIIRR209 pKa = 11.84HH210 pKa = 5.91LIARR214 pKa = 11.84KK215 pKa = 9.27VNVVRR220 pKa = 11.84LIIRR224 pKa = 11.84HH225 pKa = 5.91LIARR229 pKa = 11.84KK230 pKa = 9.27VNVVRR235 pKa = 11.84LIIRR239 pKa = 11.84HH240 pKa = 5.55LNARR244 pKa = 11.84HH245 pKa = 5.07LNARR249 pKa = 11.84KK250 pKa = 10.39VNVHH254 pKa = 6.53LIARR258 pKa = 11.84KK259 pKa = 9.14VNVVRR264 pKa = 11.84LIIRR268 pKa = 11.84HH269 pKa = 5.17LNARR273 pKa = 11.84KK274 pKa = 9.83VNVVRR279 pKa = 11.84LIILHH284 pKa = 6.41LIARR288 pKa = 11.84KK289 pKa = 9.81VNVVRR294 pKa = 11.84LIIRR298 pKa = 11.84HH299 pKa = 5.91LIARR303 pKa = 11.84KK304 pKa = 9.27VNVVRR309 pKa = 11.84LIIRR313 pKa = 11.84HH314 pKa = 5.17LNARR318 pKa = 11.84KK319 pKa = 10.12VNVVHH324 pKa = 7.05LIIRR328 pKa = 11.84HH329 pKa = 5.63LIARR333 pKa = 11.84KK334 pKa = 9.27VNVVRR339 pKa = 11.84LIIQHH344 pKa = 6.61LIARR348 pKa = 11.84KK349 pKa = 8.99VNVVRR354 pKa = 11.84LIIRR358 pKa = 11.84HH359 pKa = 5.17LNARR363 pKa = 11.84KK364 pKa = 9.83VNVVRR369 pKa = 11.84LIIRR373 pKa = 11.84HH374 pKa = 5.91LIARR378 pKa = 11.84KK379 pKa = 9.27VNVVRR384 pKa = 11.84LIIRR388 pKa = 11.84HH389 pKa = 5.91LIARR393 pKa = 11.84KK394 pKa = 9.27VNVVRR399 pKa = 11.84LIIRR403 pKa = 11.84HH404 pKa = 5.91LIARR408 pKa = 11.84KK409 pKa = 9.27VNVVRR414 pKa = 11.84LIIRR418 pKa = 11.84HH419 pKa = 5.17LNARR423 pKa = 11.84KK424 pKa = 9.83VNVVRR429 pKa = 11.84LIIRR433 pKa = 11.84HH434 pKa = 5.29LNARR438 pKa = 11.84KK439 pKa = 9.99ANVVRR444 pKa = 11.84LIIRR448 pKa = 11.84HH449 pKa = 5.17LNARR453 pKa = 11.84KK454 pKa = 9.83VNVVRR459 pKa = 11.84LIIRR463 pKa = 11.84HH464 pKa = 5.91LIARR468 pKa = 11.84KK469 pKa = 9.27VNVVRR474 pKa = 11.84LIIRR478 pKa = 11.84HH479 pKa = 5.91LIARR483 pKa = 11.84KK484 pKa = 9.27VNVVRR489 pKa = 11.84LIIRR493 pKa = 11.84HH494 pKa = 5.91LIARR498 pKa = 11.84KK499 pKa = 9.27VNVVRR504 pKa = 11.84LIIRR508 pKa = 11.84HH509 pKa = 5.17LNARR513 pKa = 11.84KK514 pKa = 10.36VNVV517 pKa = 3.29

Molecular weight:
60.71 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10375

1032

11407

4607059

9

18900

403.9

44.84

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.042 ± 0.029

2.376 ± 0.025

5.078 ± 0.019

6.47 ± 0.032

3.634 ± 0.018

7.049 ± 0.034

2.772 ± 0.014

3.971 ± 0.02

4.81 ± 0.031

9.97 ± 0.041

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.235 ± 0.012

3.419 ± 0.019

5.557 ± 0.032

4.355 ± 0.025

6.482 ± 0.025

7.628 ± 0.026

5.287 ± 0.024

6.914 ± 0.021

1.28 ± 0.01

2.666 ± 0.014

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski