Lipotes vexillifer (Yangtze river dolphin)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Artiodactyla;

Average proteome isoelectric point is 6.64

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 26003 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A340Y3F5|A0A340Y3F5_LIPVE protein tyrosine phosphatase domain-containing protein 1 isoform X1 OS=Lipotes vexillifer OX=118797 GN=PTPDC1 PE=4 SV=1
MM1 pKa = 8.24DD2 pKa = 4.75FQQLADD8 pKa = 4.22VAEE11 pKa = 4.71KK12 pKa = 9.75WCSNTPFEE20 pKa = 5.73LIATEE25 pKa = 3.96EE26 pKa = 4.32TEE28 pKa = 4.33RR29 pKa = 11.84RR30 pKa = 11.84MDD32 pKa = 4.29FYY34 pKa = 11.47ADD36 pKa = 3.74PGVSFYY42 pKa = 10.98VLCPDD47 pKa = 4.64NGCGDD52 pKa = 3.96NFHH55 pKa = 6.3VWSEE59 pKa = 4.48SEE61 pKa = 3.97DD62 pKa = 3.63CLPFLQLAQDD72 pKa = 4.45YY73 pKa = 10.71ISSCGKK79 pKa = 8.56KK80 pKa = 7.94TLHH83 pKa = 6.31EE84 pKa = 4.11VLEE87 pKa = 4.47KK88 pKa = 10.61VFKK91 pKa = 10.63SFRR94 pKa = 11.84PLLGLPDD101 pKa = 4.83ADD103 pKa = 3.93DD104 pKa = 4.59DD105 pKa = 4.62AFEE108 pKa = 4.77EE109 pKa = 4.52YY110 pKa = 10.51SADD113 pKa = 3.68VEE115 pKa = 4.38EE116 pKa = 5.09EE117 pKa = 4.2EE118 pKa = 5.29PEE120 pKa = 4.13ADD122 pKa = 3.66HH123 pKa = 6.65PQMGVSQQQ131 pKa = 3.0

Molecular weight: 14.93 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A340Y9I5|A0A340Y9I5_LIPVE Acyl-coenzyme A oxidase OS=Lipotes vexillifer OX=118797 GN=ACOX2 PE=3 SV=1
MM1 pKa = 7.02STPVTQRR8 pKa = 11.84RR9 pKa = 11.84SAASTPITQSPLPSLSAAAQHH30 pKa = 6.43RR31 pKa = 11.84LPSLSARR38 pKa = 11.84HH39 pKa = 5.87SSASTPVTQRR49 pKa = 11.84RR50 pKa = 11.84SAASTPITQRR60 pKa = 11.84RR61 pKa = 11.84STASTLVAQRR71 pKa = 11.84RR72 pKa = 11.84STASTPVTQRR82 pKa = 11.84RR83 pKa = 11.84SSASTPVAQRR93 pKa = 11.84RR94 pKa = 11.84SSASTPVAQRR104 pKa = 11.84RR105 pKa = 11.84SSASTPVAQRR115 pKa = 11.84HH116 pKa = 5.31SSASTPVTQRR126 pKa = 11.84RR127 pKa = 11.84SAASTPITQRR137 pKa = 11.84RR138 pKa = 11.84STASTLVAQRR148 pKa = 11.84RR149 pKa = 11.84STASTPVTQRR159 pKa = 11.84RR160 pKa = 11.84SSASTPVAQRR170 pKa = 11.84RR171 pKa = 11.84SSASTPVAQRR181 pKa = 11.84RR182 pKa = 11.84SSASTPVAQRR192 pKa = 11.84HH193 pKa = 5.31SSASTPVTQRR203 pKa = 11.84RR204 pKa = 11.84SAASTPITHH213 pKa = 6.64CHH215 pKa = 5.73SSAPTLPQIPASLLPQVNSTQPP237 pKa = 2.97

Molecular weight: 24.82 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

18846

7157

26003

15020484

22

35482

577.6

64.24

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.228 ± 0.015

2.136 ± 0.011

4.886 ± 0.011

7.107 ± 0.019

3.598 ± 0.011

6.705 ± 0.02

2.564 ± 0.008

4.311 ± 0.014

5.648 ± 0.016

9.884 ± 0.022

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.148 ± 0.006

3.544 ± 0.01

6.317 ± 0.024

4.747 ± 0.016

5.782 ± 0.014

8.19 ± 0.018

5.217 ± 0.012

6.101 ± 0.015

1.199 ± 0.005

2.641 ± 0.008
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski