Amino acid dipepetide frequency for Yongsan tombus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.89AlaAla: 4.89 ± 0.972
0.815AlaCys: 0.815 ± 0.592
4.075AlaAsp: 4.075 ± 0.681
4.075AlaGlu: 4.075 ± 0.925
3.26AlaPhe: 3.26 ± 1.817
4.89AlaGly: 4.89 ± 0.366
1.63AlaHis: 1.63 ± 0.636
4.075AlaIle: 4.075 ± 1.943
6.52AlaLys: 6.52 ± 1.395
6.52AlaLeu: 6.52 ± 2.69
2.445AlaMet: 2.445 ± 1.035
1.63AlaAsn: 1.63 ± 0.755
7.335AlaPro: 7.335 ± 0.549
3.26AlaGln: 3.26 ± 1.598
4.075AlaArg: 4.075 ± 0.388
8.15AlaSer: 8.15 ± 2.045
6.52AlaThr: 6.52 ± 1.374
4.075AlaVal: 4.075 ± 1.488
1.63AlaTrp: 1.63 ± 1.184
0.815AlaTyr: 0.815 ± 0.592
0.0AlaXaa: 0.0 ± 0.0
Cys
1.63CysAla: 1.63 ± 0.511
0.0CysCys: 0.0 ± 0.0
1.63CysAsp: 1.63 ± 1.184
0.815CysGlu: 0.815 ± 0.592
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.445CysIle: 2.445 ± 1.776
1.63CysLys: 1.63 ± 0.511
0.815CysLeu: 0.815 ± 0.592
0.0CysMet: 0.0 ± 0.0
0.815CysAsn: 0.815 ± 0.592
0.0CysPro: 0.0 ± 0.0
1.63CysGln: 1.63 ± 1.184
0.815CysArg: 0.815 ± 0.592
0.815CysSer: 0.815 ± 0.592
0.0CysThr: 0.0 ± 0.0
1.63CysVal: 1.63 ± 1.184
0.815CysTrp: 0.815 ± 0.642
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.815AspAla: 0.815 ± 0.592
0.815AspCys: 0.815 ± 0.592
1.63AspAsp: 1.63 ± 1.184
1.63AspGlu: 1.63 ± 1.326
2.445AspPhe: 2.445 ± 1.035
4.89AspGly: 4.89 ± 1.623
4.075AspHis: 4.075 ± 2.123
1.63AspIle: 1.63 ± 1.184
3.26AspLys: 3.26 ± 1.272
2.445AspLeu: 2.445 ± 0.183
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
2.445AspPro: 2.445 ± 0.901
2.445AspGln: 2.445 ± 0.901
2.445AspArg: 2.445 ± 0.183
2.445AspSer: 2.445 ± 1.776
1.63AspThr: 1.63 ± 1.326
2.445AspVal: 2.445 ± 0.998
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.26GluAla: 3.26 ± 1.877
0.815GluCys: 0.815 ± 0.592
0.0GluAsp: 0.0 ± 0.0
7.335GluGlu: 7.335 ± 1.634
1.63GluPhe: 1.63 ± 1.283
0.815GluGly: 0.815 ± 0.663
4.89GluHis: 4.89 ± 2.697
2.445GluIle: 2.445 ± 0.183
0.0GluLys: 0.0 ± 0.0
5.705GluLeu: 5.705 ± 1.679
0.0GluMet: 0.0 ± 0.0
0.815GluAsn: 0.815 ± 0.642
3.26GluPro: 3.26 ± 0.827
2.445GluGln: 2.445 ± 0.901
4.075GluArg: 4.075 ± 0.681
1.63GluSer: 1.63 ± 1.326
0.815GluThr: 0.815 ± 0.663
3.26GluVal: 3.26 ± 1.022
1.63GluTrp: 1.63 ± 1.184
0.815GluTyr: 0.815 ± 0.592
0.0GluXaa: 0.0 ± 0.0
Phe
2.445PheAla: 2.445 ± 0.183
0.815PheCys: 0.815 ± 0.592
2.445PheAsp: 2.445 ± 1.035
1.63PheGlu: 1.63 ± 0.511
0.815PhePhe: 0.815 ± 0.663
0.815PheGly: 0.815 ± 0.592
0.0PheHis: 0.0 ± 0.0
2.445PheIle: 2.445 ± 0.183
0.815PheLys: 0.815 ± 0.592
4.89PheLeu: 4.89 ± 0.718
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.815PhePro: 0.815 ± 0.642
2.445PheGln: 2.445 ± 1.234
0.0PheArg: 0.0 ± 0.0
1.63PheSer: 1.63 ± 1.283
4.89PheThr: 4.89 ± 0.718
1.63PheVal: 1.63 ± 0.511
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.705GlyAla: 5.705 ± 2.605
0.0GlyCys: 0.0 ± 0.0
3.26GlyAsp: 3.26 ± 1.437
1.63GlyGlu: 1.63 ± 0.755
1.63GlyPhe: 1.63 ± 1.184
3.26GlyGly: 3.26 ± 0.697
3.26GlyHis: 3.26 ± 0.827
1.63GlyIle: 1.63 ± 0.636
0.0GlyLys: 0.0 ± 0.0
5.705GlyLeu: 5.705 ± 1.258
1.63GlyMet: 1.63 ± 0.636
4.075GlyAsn: 4.075 ± 0.388
3.26GlyPro: 3.26 ± 0.827
2.445GlyGln: 2.445 ± 0.183
4.075GlyArg: 4.075 ± 2.004
6.52GlySer: 6.52 ± 0.891
3.26GlyThr: 3.26 ± 0.697
2.445GlyVal: 2.445 ± 0.183
0.0GlyTrp: 0.0 ± 0.0
1.63GlyTyr: 1.63 ± 0.511
0.0GlyXaa: 0.0 ± 0.0
His
3.26HisAla: 3.26 ± 1.272
0.0HisCys: 0.0 ± 0.0
0.815HisAsp: 0.815 ± 0.663
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.63HisGly: 1.63 ± 1.184
0.0HisHis: 0.0 ± 0.0
0.815HisIle: 0.815 ± 0.592
3.26HisLys: 3.26 ± 1.561
4.075HisLeu: 4.075 ± 1.612
0.0HisMet: 0.0 ± 0.0
2.445HisAsn: 2.445 ± 1.776
3.26HisPro: 3.26 ± 0.697
1.63HisGln: 1.63 ± 0.636
0.815HisArg: 0.815 ± 0.592
3.26HisSer: 3.26 ± 0.697
1.63HisThr: 1.63 ± 1.184
3.26HisVal: 3.26 ± 1.561
0.815HisTrp: 0.815 ± 0.592
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.52IleAla: 6.52 ± 2.045
0.815IleCys: 0.815 ± 0.642
3.26IleAsp: 3.26 ± 1.561
3.26IleGlu: 3.26 ± 1.272
0.0IlePhe: 0.0 ± 0.0
2.445IleGly: 2.445 ± 0.183
0.0IleHis: 0.0 ± 0.0
2.445IleIle: 2.445 ± 0.901
0.0IleLys: 0.0 ± 0.0
1.63IleLeu: 1.63 ± 0.755
0.0IleMet: 0.0 ± 0.0
2.445IleAsn: 2.445 ± 1.776
3.26IlePro: 3.26 ± 0.446
3.26IleGln: 3.26 ± 1.022
1.63IleArg: 1.63 ± 1.283
3.26IleSer: 3.26 ± 1.022
8.15IleThr: 8.15 ± 0.915
2.445IleVal: 2.445 ± 0.901
0.0IleTrp: 0.0 ± 0.0
1.63IleTyr: 1.63 ± 0.755
0.0IleXaa: 0.0 ± 0.0
Lys
2.445LysAla: 2.445 ± 1.776
0.0LysCys: 0.0 ± 0.0
2.445LysAsp: 2.445 ± 1.035
0.0LysGlu: 0.0 ± 0.0
2.445LysPhe: 2.445 ± 1.156
4.075LysGly: 4.075 ± 1.612
4.075LysHis: 4.075 ± 1.612
0.815LysIle: 0.815 ± 0.642
3.26LysLys: 3.26 ± 0.697
6.52LysLeu: 6.52 ± 0.326
3.26LysMet: 3.26 ± 1.191
2.445LysAsn: 2.445 ± 0.901
1.63LysPro: 1.63 ± 0.511
2.445LysGln: 2.445 ± 0.901
2.445LysArg: 2.445 ± 0.901
1.63LysSer: 1.63 ± 0.636
4.075LysThr: 4.075 ± 0.388
1.63LysVal: 1.63 ± 0.636
1.63LysTrp: 1.63 ± 0.511
1.63LysTyr: 1.63 ± 0.636
0.0LysXaa: 0.0 ± 0.0
Leu
4.075LeuAla: 4.075 ± 0.388
0.815LeuCys: 0.815 ± 0.592
2.445LeuAsp: 2.445 ± 1.035
8.15LeuGlu: 8.15 ± 1.372
4.075LeuPhe: 4.075 ± 1.943
3.26LeuGly: 3.26 ± 1.272
0.815LeuHis: 0.815 ± 0.592
3.26LeuIle: 3.26 ± 0.446
4.89LeuLys: 4.89 ± 2.697
10.595LeuLeu: 10.595 ± 0.381
0.815LeuMet: 0.815 ± 0.642
4.075LeuAsn: 4.075 ± 1.488
6.52LeuPro: 6.52 ± 0.891
4.89LeuGln: 4.89 ± 2.15
9.78LeuArg: 9.78 ± 0.946
8.965LeuSer: 8.965 ± 2.605
4.89LeuThr: 4.89 ± 3.054
5.705LeuVal: 5.705 ± 1.589
0.0LeuTrp: 0.0 ± 0.0
5.705LeuTyr: 5.705 ± 2.586
0.0LeuXaa: 0.0 ± 0.0
Met
0.815MetAla: 0.815 ± 0.642
0.0MetCys: 0.0 ± 0.0
0.815MetAsp: 0.815 ± 0.592
0.815MetGlu: 0.815 ± 0.592
1.63MetPhe: 1.63 ± 1.184
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.815MetIle: 0.815 ± 0.642
2.445MetLys: 2.445 ± 1.776
1.63MetLeu: 1.63 ± 0.511
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.815MetPro: 0.815 ± 0.642
0.815MetGln: 0.815 ± 0.642
2.445MetArg: 2.445 ± 1.988
1.63MetSer: 1.63 ± 1.184
1.63MetThr: 1.63 ± 0.636
0.815MetVal: 0.815 ± 0.663
1.63MetTrp: 1.63 ± 1.326
0.815MetTyr: 0.815 ± 0.642
0.0MetXaa: 0.0 ± 0.0
Asn
1.63AsnAla: 1.63 ± 1.283
1.63AsnCys: 1.63 ± 1.184
1.63AsnAsp: 1.63 ± 1.184
1.63AsnGlu: 1.63 ± 1.184
0.815AsnPhe: 0.815 ± 0.642
3.26AsnGly: 3.26 ± 1.022
0.0AsnHis: 0.0 ± 0.0
2.445AsnIle: 2.445 ± 0.998
4.075AsnLys: 4.075 ± 1.612
4.89AsnLeu: 4.89 ± 1.908
1.63AsnMet: 1.63 ± 0.511
1.63AsnAsn: 1.63 ± 0.636
2.445AsnPro: 2.445 ± 0.998
2.445AsnGln: 2.445 ± 0.183
0.815AsnArg: 0.815 ± 0.592
4.075AsnSer: 4.075 ± 0.925
4.89AsnThr: 4.89 ± 1.268
1.63AsnVal: 1.63 ± 0.511
2.445AsnTrp: 2.445 ± 0.901
0.815AsnTyr: 0.815 ± 0.592
0.0AsnXaa: 0.0 ± 0.0
Pro
6.52ProAla: 6.52 ± 2.69
0.815ProCys: 0.815 ± 0.592
0.815ProAsp: 0.815 ± 0.663
3.26ProGlu: 3.26 ± 1.272
1.63ProPhe: 1.63 ± 1.184
4.075ProGly: 4.075 ± 1.45
3.26ProHis: 3.26 ± 0.697
6.52ProIle: 6.52 ± 1.374
1.63ProLys: 1.63 ± 1.326
4.89ProLeu: 4.89 ± 1.965
0.0ProMet: 0.0 ± 0.0
4.075ProAsn: 4.075 ± 0.681
3.26ProPro: 3.26 ± 0.827
2.445ProGln: 2.445 ± 0.183
4.89ProArg: 4.89 ± 1.45
5.705ProSer: 5.705 ± 3.684
4.075ProThr: 4.075 ± 1.943
8.15ProVal: 8.15 ± 1.85
1.63ProTrp: 1.63 ± 1.184
0.815ProTyr: 0.815 ± 0.663
0.0ProXaa: 0.0 ± 0.0
Gln
4.89GlnAla: 4.89 ± 2.264
2.445GlnCys: 2.445 ± 1.776
0.0GlnAsp: 0.0 ± 0.0
0.815GlnGlu: 0.815 ± 0.663
0.815GlnPhe: 0.815 ± 0.592
2.445GlnGly: 2.445 ± 0.998
0.815GlnHis: 0.815 ± 0.663
0.815GlnIle: 0.815 ± 0.592
0.815GlnLys: 0.815 ± 0.642
3.26GlnLeu: 3.26 ± 0.446
1.63GlnMet: 1.63 ± 0.511
1.63GlnAsn: 1.63 ± 0.511
3.26GlnPro: 3.26 ± 1.817
2.445GlnGln: 2.445 ± 0.901
4.89GlnArg: 4.89 ± 0.718
4.89GlnSer: 4.89 ± 2.469
3.26GlnThr: 3.26 ± 1.598
3.26GlnVal: 3.26 ± 1.51
0.0GlnTrp: 0.0 ± 0.0
3.26GlnTyr: 3.26 ± 1.437
0.0GlnXaa: 0.0 ± 0.0
Arg
8.965ArgAla: 8.965 ± 4.042
0.815ArgCys: 0.815 ± 0.592
2.445ArgAsp: 2.445 ± 1.156
1.63ArgGlu: 1.63 ± 0.755
0.815ArgPhe: 0.815 ± 0.592
2.445ArgGly: 2.445 ± 0.183
1.63ArgHis: 1.63 ± 1.184
0.815ArgIle: 0.815 ± 0.642
4.89ArgLys: 4.89 ± 1.623
7.335ArgLeu: 7.335 ± 2.425
2.445ArgMet: 2.445 ± 1.035
5.705ArgAsn: 5.705 ± 1.458
4.89ArgPro: 4.89 ± 2.312
2.445ArgGln: 2.445 ± 1.234
6.52ArgArg: 6.52 ± 2.69
6.52ArgSer: 6.52 ± 2.69
2.445ArgThr: 2.445 ± 1.234
4.89ArgVal: 4.89 ± 1.36
0.815ArgTrp: 0.815 ± 0.642
3.26ArgTyr: 3.26 ± 1.561
0.0ArgXaa: 0.0 ± 0.0
Ser
7.335SerAla: 7.335 ± 0.549
2.445SerCys: 2.445 ± 0.901
0.0SerAsp: 0.0 ± 0.0
3.26SerGlu: 3.26 ± 1.022
0.815SerPhe: 0.815 ± 0.642
7.335SerGly: 7.335 ± 2.591
1.63SerHis: 1.63 ± 0.636
2.445SerIle: 2.445 ± 0.998
3.26SerLys: 3.26 ± 0.697
9.78SerLeu: 9.78 ± 1.645
0.815SerMet: 0.815 ± 0.592
3.26SerAsn: 3.26 ± 1.022
9.78SerPro: 9.78 ± 3.575
3.26SerGln: 3.26 ± 1.817
4.075SerArg: 4.075 ± 1.488
4.075SerSer: 4.075 ± 1.978
8.15SerThr: 8.15 ± 2.976
2.445SerVal: 2.445 ± 1.267
0.0SerTrp: 0.0 ± 0.0
1.63SerTyr: 1.63 ± 1.184
0.0SerXaa: 0.0 ± 0.0
Thr
4.89ThrAla: 4.89 ± 2.264
0.0ThrCys: 0.0 ± 0.0
2.445ThrAsp: 2.445 ± 0.901
2.445ThrGlu: 2.445 ± 1.925
1.63ThrPhe: 1.63 ± 0.511
3.26ThrGly: 3.26 ± 1.598
2.445ThrHis: 2.445 ± 1.776
5.705ThrIle: 5.705 ± 0.998
4.075ThrLys: 4.075 ± 1.744
4.89ThrLeu: 4.89 ± 0.962
1.63ThrMet: 1.63 ± 1.076
2.445ThrAsn: 2.445 ± 0.998
8.15ThrPro: 8.15 ± 1.85
2.445ThrGln: 2.445 ± 0.183
8.15ThrArg: 8.15 ± 3.041
4.89ThrSer: 4.89 ± 1.36
11.41ThrThr: 11.41 ± 3.348
8.15ThrVal: 8.15 ± 2.655
0.815ThrTrp: 0.815 ± 0.642
0.815ThrTyr: 0.815 ± 0.592
0.0ThrXaa: 0.0 ± 0.0
Val
8.15ValAla: 8.15 ± 1.601
2.445ValCys: 2.445 ± 0.901
4.89ValAsp: 4.89 ± 0.962
0.815ValGlu: 0.815 ± 0.663
4.075ValPhe: 4.075 ± 1.34
4.075ValGly: 4.075 ± 0.681
0.815ValHis: 0.815 ± 0.592
3.26ValIle: 3.26 ± 1.437
0.815ValLys: 0.815 ± 0.592
3.26ValLeu: 3.26 ± 1.022
1.63ValMet: 1.63 ± 0.755
4.075ValAsn: 4.075 ± 0.925
4.075ValPro: 4.075 ± 1.943
0.815ValGln: 0.815 ± 0.642
7.335ValArg: 7.335 ± 1.634
4.075ValSer: 4.075 ± 1.488
4.075ValThr: 4.075 ± 1.943
4.075ValVal: 4.075 ± 2.429
0.815ValTrp: 0.815 ± 0.592
2.445ValTyr: 2.445 ± 0.183
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.815TrpAsp: 0.815 ± 0.592
1.63TrpGlu: 1.63 ± 0.755
0.0TrpPhe: 0.0 ± 0.0
0.815TrpGly: 0.815 ± 0.592
0.815TrpHis: 0.815 ± 0.642
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.63TrpLeu: 1.63 ± 1.184
0.0TrpMet: 0.0 ± 0.0
1.63TrpAsn: 1.63 ± 0.511
0.0TrpPro: 0.0 ± 0.0
0.815TrpGln: 0.815 ± 0.642
1.63TrpArg: 1.63 ± 0.636
0.0TrpSer: 0.0 ± 0.0
1.63TrpThr: 1.63 ± 0.511
1.63TrpVal: 1.63 ± 1.184
0.0TrpTrp: 0.0 ± 0.0
1.63TrpTyr: 1.63 ± 1.184
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.445TyrAla: 2.445 ± 1.035
0.0TyrCys: 0.0 ± 0.0
1.63TyrAsp: 1.63 ± 0.511
0.815TyrGlu: 0.815 ± 0.592
0.0TyrPhe: 0.0 ± 0.0
1.63TyrGly: 1.63 ± 1.184
0.815TyrHis: 0.815 ± 0.592
1.63TyrIle: 1.63 ± 1.184
3.26TyrLys: 3.26 ± 1.022
3.26TyrLeu: 3.26 ± 1.877
0.815TyrMet: 0.815 ± 0.51
1.63TyrAsn: 1.63 ± 1.184
0.0TyrPro: 0.0 ± 0.0
0.815TyrGln: 0.815 ± 0.642
0.815TyrArg: 0.815 ± 0.592
1.63TyrSer: 1.63 ± 1.283
4.075TyrThr: 4.075 ± 1.34
2.445TyrVal: 2.445 ± 0.183
0.0TyrTrp: 0.0 ± 0.0
1.63TyrTyr: 1.63 ± 0.511
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1228 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski