Amino acid dipepetide frequency for Capybara microvirus Cap3_SP_443

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.874AlaAla: 8.874 ± 4.111
0.683AlaCys: 0.683 ± 0.666
2.73AlaAsp: 2.73 ± 1.251
6.143AlaGlu: 6.143 ± 2.676
2.048AlaPhe: 2.048 ± 1.329
9.556AlaGly: 9.556 ± 3.544
1.365AlaHis: 1.365 ± 1.46
1.365AlaIle: 1.365 ± 0.915
5.461AlaLys: 5.461 ± 1.538
4.778AlaLeu: 4.778 ± 2.093
2.73AlaMet: 2.73 ± 1.29
5.461AlaAsn: 5.461 ± 3.284
3.413AlaPro: 3.413 ± 1.241
4.096AlaGln: 4.096 ± 0.968
4.778AlaArg: 4.778 ± 2.272
5.461AlaSer: 5.461 ± 2.635
4.778AlaThr: 4.778 ± 1.377
6.143AlaVal: 6.143 ± 2.889
0.683AlaTrp: 0.683 ± 0.73
4.096AlaTyr: 4.096 ± 0.738
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.683CysGlu: 0.683 ± 0.666
0.683CysPhe: 0.683 ± 0.666
2.048CysGly: 2.048 ± 1.999
0.0CysHis: 0.0 ± 0.0
0.683CysIle: 0.683 ± 0.666
0.0CysLys: 0.0 ± 0.0
0.683CysLeu: 0.683 ± 0.423
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.683CysGln: 0.683 ± 0.666
0.683CysArg: 0.683 ± 0.666
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.683CysVal: 0.683 ± 0.866
0.683CysTrp: 0.683 ± 0.666
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.73AspAla: 2.73 ± 1.915
0.0AspCys: 0.0 ± 0.0
2.73AspAsp: 2.73 ± 1.226
9.556AspGlu: 9.556 ± 3.625
2.048AspPhe: 2.048 ± 1.132
6.143AspGly: 6.143 ± 1.05
2.048AspHis: 2.048 ± 0.852
0.683AspIle: 0.683 ± 0.423
2.048AspLys: 2.048 ± 0.852
5.461AspLeu: 5.461 ± 1.551
2.048AspMet: 2.048 ± 0.665
2.73AspAsn: 2.73 ± 2.464
2.048AspPro: 2.048 ± 1.132
3.413AspGln: 3.413 ± 1.311
0.683AspArg: 0.683 ± 0.423
3.413AspSer: 3.413 ± 1.552
4.778AspThr: 4.778 ± 0.782
1.365AspVal: 1.365 ± 0.685
1.365AspTrp: 1.365 ± 0.561
2.73AspTyr: 2.73 ± 1.111
0.0AspXaa: 0.0 ± 0.0
Glu
5.461GluAla: 5.461 ± 2.372
0.683GluCys: 0.683 ± 0.666
3.413GluAsp: 3.413 ± 1.638
3.413GluGlu: 3.413 ± 1.085
2.048GluPhe: 2.048 ± 1.268
4.778GluGly: 4.778 ± 0.865
2.048GluHis: 2.048 ± 0.737
6.143GluIle: 6.143 ± 1.868
4.778GluLys: 4.778 ± 1.217
4.778GluLeu: 4.778 ± 1.162
2.048GluMet: 2.048 ± 1.366
4.096GluAsn: 4.096 ± 2.292
2.73GluPro: 2.73 ± 0.929
3.413GluGln: 3.413 ± 0.873
2.73GluArg: 2.73 ± 1.803
4.096GluSer: 4.096 ± 1.289
5.461GluThr: 5.461 ± 2.048
4.096GluVal: 4.096 ± 2.044
0.0GluTrp: 0.0 ± 0.0
4.778GluTyr: 4.778 ± 3.783
0.0GluXaa: 0.0 ± 0.0
Phe
2.048PheAla: 2.048 ± 0.897
0.683PheCys: 0.683 ± 0.423
2.73PheAsp: 2.73 ± 1.958
1.365PheGlu: 1.365 ± 0.915
2.73PhePhe: 2.73 ± 1.063
2.048PheGly: 2.048 ± 0.507
1.365PheHis: 1.365 ± 0.561
4.096PheIle: 4.096 ± 1.486
1.365PheLys: 1.365 ± 0.915
2.048PheLeu: 2.048 ± 1.717
2.048PheMet: 2.048 ± 0.782
1.365PheAsn: 1.365 ± 1.332
0.683PhePro: 0.683 ± 0.423
1.365PheGln: 1.365 ± 0.915
0.683PheArg: 0.683 ± 0.423
2.73PheSer: 2.73 ± 0.851
4.096PheThr: 4.096 ± 1.836
2.73PheVal: 2.73 ± 0.929
0.683PheTrp: 0.683 ± 0.423
2.048PheTyr: 2.048 ± 0.782
0.0PheXaa: 0.0 ± 0.0
Gly
8.191GlyAla: 8.191 ± 3.933
0.683GlyCys: 0.683 ± 0.666
6.826GlyAsp: 6.826 ± 3.485
11.604GlyGlu: 11.604 ± 1.48
2.73GlyPhe: 2.73 ± 1.37
6.826GlyGly: 6.826 ± 3.422
0.683GlyHis: 0.683 ± 0.423
3.413GlyIle: 3.413 ± 1.729
5.461GlyLys: 5.461 ± 1.097
7.509GlyLeu: 7.509 ± 1.771
2.048GlyMet: 2.048 ± 0.897
2.048GlyAsn: 2.048 ± 0.861
2.048GlyPro: 2.048 ± 1.157
2.73GlyGln: 2.73 ± 1.472
1.365GlyArg: 1.365 ± 0.779
5.461GlySer: 5.461 ± 1.597
2.048GlyThr: 2.048 ± 0.897
6.143GlyVal: 6.143 ± 1.933
0.0GlyTrp: 0.0 ± 0.0
8.191GlyTyr: 8.191 ± 2.553
0.0GlyXaa: 0.0 ± 0.0
His
0.683HisAla: 0.683 ± 0.73
0.0HisCys: 0.0 ± 0.0
2.048HisAsp: 2.048 ± 0.852
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.73HisGly: 2.73 ± 0.514
1.365HisHis: 1.365 ± 0.845
0.683HisIle: 0.683 ± 0.666
2.73HisLys: 2.73 ± 1.624
0.683HisLeu: 0.683 ± 0.666
1.365HisMet: 1.365 ± 0.735
1.365HisAsn: 1.365 ± 0.561
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.683HisArg: 0.683 ± 0.666
2.048HisSer: 2.048 ± 0.897
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.683HisTrp: 0.683 ± 0.423
1.365HisTyr: 1.365 ± 0.561
0.0HisXaa: 0.0 ± 0.0
Ile
2.048IleAla: 2.048 ± 0.897
0.0IleCys: 0.0 ± 0.0
2.048IleAsp: 2.048 ± 1.268
4.778IleGlu: 4.778 ± 1.031
2.048IlePhe: 2.048 ± 1.132
3.413IleGly: 3.413 ± 1.165
0.683IleHis: 0.683 ± 0.666
4.096IleIle: 4.096 ± 2.629
4.096IleLys: 4.096 ± 0.738
3.413IleLeu: 3.413 ± 1.11
2.73IleMet: 2.73 ± 1.281
2.73IleAsn: 2.73 ± 1.399
1.365IlePro: 1.365 ± 1.332
2.73IleGln: 2.73 ± 1.123
4.096IleArg: 4.096 ± 1.223
0.683IleSer: 0.683 ± 0.666
1.365IleThr: 1.365 ± 0.7
2.048IleVal: 2.048 ± 1.268
2.048IleTrp: 2.048 ± 1.157
2.73IleTyr: 2.73 ± 0.713
0.0IleXaa: 0.0 ± 0.0
Lys
6.826LysAla: 6.826 ± 1.555
0.0LysCys: 0.0 ± 0.0
4.096LysAsp: 4.096 ± 2.63
3.413LysGlu: 3.413 ± 1.375
2.73LysPhe: 2.73 ± 1.281
6.826LysGly: 6.826 ± 1.391
0.683LysHis: 0.683 ± 0.666
5.461LysIle: 5.461 ± 1.426
2.73LysLys: 2.73 ± 1.849
3.413LysLeu: 3.413 ± 0.747
2.048LysMet: 2.048 ± 0.737
1.365LysAsn: 1.365 ± 0.685
4.096LysPro: 4.096 ± 1.651
0.683LysGln: 0.683 ± 0.666
2.73LysArg: 2.73 ± 1.803
3.413LysSer: 3.413 ± 0.783
2.73LysThr: 2.73 ± 0.713
2.73LysVal: 2.73 ± 1.888
2.048LysTrp: 2.048 ± 0.737
2.73LysTyr: 2.73 ± 1.063
0.0LysXaa: 0.0 ± 0.0
Leu
4.096LeuAla: 4.096 ± 1.703
0.683LeuCys: 0.683 ± 0.666
5.461LeuAsp: 5.461 ± 1.836
4.778LeuGlu: 4.778 ± 1.217
3.413LeuPhe: 3.413 ± 1.241
5.461LeuGly: 5.461 ± 1.966
0.683LeuHis: 0.683 ± 0.866
0.683LeuIle: 0.683 ± 0.423
5.461LeuLys: 5.461 ± 1.878
2.73LeuLeu: 2.73 ± 0.718
0.683LeuMet: 0.683 ± 0.789
1.365LeuAsn: 1.365 ± 0.915
6.143LeuPro: 6.143 ± 2.347
2.73LeuGln: 2.73 ± 0.929
3.413LeuArg: 3.413 ± 0.747
5.461LeuSer: 5.461 ± 1.362
3.413LeuThr: 3.413 ± 1.11
1.365LeuVal: 1.365 ± 0.845
0.683LeuTrp: 0.683 ± 0.423
1.365LeuTyr: 1.365 ± 0.845
0.0LeuXaa: 0.0 ± 0.0
Met
6.826MetAla: 6.826 ± 2.17
0.0MetCys: 0.0 ± 0.0
1.365MetAsp: 1.365 ± 0.845
2.048MetGlu: 2.048 ± 1.717
0.683MetPhe: 0.683 ± 0.423
3.413MetGly: 3.413 ± 2.113
0.0MetHis: 0.0 ± 0.0
1.365MetIle: 1.365 ± 0.7
4.096MetLys: 4.096 ± 2.664
0.683MetLeu: 0.683 ± 0.423
2.73MetMet: 2.73 ± 1.91
0.683MetAsn: 0.683 ± 0.423
0.683MetPro: 0.683 ± 0.423
2.048MetGln: 2.048 ± 1.268
2.048MetArg: 2.048 ± 1.132
2.73MetSer: 2.73 ± 0.955
1.365MetThr: 1.365 ± 0.7
0.0MetVal: 0.0 ± 0.0
0.683MetTrp: 0.683 ± 0.423
0.683MetTyr: 0.683 ± 0.789
0.0MetXaa: 0.0 ± 0.0
Asn
2.73AsnAla: 2.73 ± 1.497
0.683AsnCys: 0.683 ± 0.666
4.096AsnAsp: 4.096 ± 1.677
2.73AsnGlu: 2.73 ± 1.063
2.048AsnPhe: 2.048 ± 1.425
4.096AsnGly: 4.096 ± 2.099
0.683AsnHis: 0.683 ± 0.666
2.73AsnIle: 2.73 ± 0.851
2.73AsnLys: 2.73 ± 1.497
3.413AsnLeu: 3.413 ± 1.451
0.683AsnMet: 0.683 ± 0.423
0.683AsnAsn: 0.683 ± 0.423
2.048AsnPro: 2.048 ± 0.507
0.683AsnGln: 0.683 ± 0.73
2.73AsnArg: 2.73 ± 1.063
2.73AsnSer: 2.73 ± 1.125
5.461AsnThr: 5.461 ± 2.8
2.048AsnVal: 2.048 ± 1.268
2.048AsnTrp: 2.048 ± 1.636
1.365AsnTyr: 1.365 ± 0.779
0.0AsnXaa: 0.0 ± 0.0
Pro
4.778ProAla: 4.778 ± 1.436
0.683ProCys: 0.683 ± 0.666
1.365ProAsp: 1.365 ± 0.561
2.73ProGlu: 2.73 ± 1.123
2.048ProPhe: 2.048 ± 1.717
4.096ProGly: 4.096 ± 1.36
0.683ProHis: 0.683 ± 0.666
4.096ProIle: 4.096 ± 1.171
1.365ProLys: 1.365 ± 0.685
4.096ProLeu: 4.096 ± 1.475
0.683ProMet: 0.683 ± 0.423
2.048ProAsn: 2.048 ± 1.268
0.683ProPro: 0.683 ± 0.666
2.048ProGln: 2.048 ± 1.268
0.0ProArg: 0.0 ± 0.0
2.048ProSer: 2.048 ± 0.861
0.0ProThr: 0.0 ± 0.0
3.413ProVal: 3.413 ± 1.582
1.365ProTrp: 1.365 ± 0.845
2.048ProTyr: 2.048 ± 1.157
0.0ProXaa: 0.0 ± 0.0
Gln
4.096GlnAla: 4.096 ± 1.718
2.048GlnCys: 2.048 ± 1.425
1.365GlnAsp: 1.365 ± 1.12
4.096GlnGlu: 4.096 ± 0.818
0.683GlnPhe: 0.683 ± 0.423
2.73GlnGly: 2.73 ± 0.851
0.0GlnHis: 0.0 ± 0.0
0.683GlnIle: 0.683 ± 0.666
4.096GlnLys: 4.096 ± 1.686
1.365GlnLeu: 1.365 ± 0.561
1.365GlnMet: 1.365 ± 0.685
3.413GlnAsn: 3.413 ± 1.467
0.683GlnPro: 0.683 ± 0.423
1.365GlnGln: 1.365 ± 0.845
3.413GlnArg: 3.413 ± 0.793
6.143GlnSer: 6.143 ± 2.235
4.096GlnThr: 4.096 ± 1.793
2.73GlnVal: 2.73 ± 0.851
0.0GlnTrp: 0.0 ± 0.0
1.365GlnTyr: 1.365 ± 0.685
0.0GlnXaa: 0.0 ± 0.0
Arg
3.413ArgAla: 3.413 ± 1.245
0.683ArgCys: 0.683 ± 0.666
3.413ArgAsp: 3.413 ± 2.46
2.73ArgGlu: 2.73 ± 1.125
2.73ArgPhe: 2.73 ± 1.624
2.73ArgGly: 2.73 ± 1.443
0.0ArgHis: 0.0 ± 0.0
1.365ArgIle: 1.365 ± 0.561
3.413ArgLys: 3.413 ± 2.46
2.73ArgLeu: 2.73 ± 1.063
3.413ArgMet: 3.413 ± 1.11
1.365ArgAsn: 1.365 ± 0.561
1.365ArgPro: 1.365 ± 0.561
2.048ArgGln: 2.048 ± 0.507
4.096ArgArg: 4.096 ± 2.775
0.683ArgSer: 0.683 ± 0.423
2.73ArgThr: 2.73 ± 0.514
5.461ArgVal: 5.461 ± 1.463
0.0ArgTrp: 0.0 ± 0.0
2.73ArgTyr: 2.73 ± 0.929
0.0ArgXaa: 0.0 ± 0.0
Ser
6.143SerAla: 6.143 ± 2.235
0.0SerCys: 0.0 ± 0.0
2.048SerAsp: 2.048 ± 0.507
6.143SerGlu: 6.143 ± 1.637
3.413SerPhe: 3.413 ± 1.582
4.096SerGly: 4.096 ± 1.015
2.048SerHis: 2.048 ± 1.366
5.461SerIle: 5.461 ± 2.125
3.413SerLys: 3.413 ± 0.793
2.73SerLeu: 2.73 ± 0.851
2.048SerMet: 2.048 ± 0.507
5.461SerAsn: 5.461 ± 2.799
2.048SerPro: 2.048 ± 0.82
2.73SerGln: 2.73 ± 1.399
6.826SerArg: 6.826 ± 1.565
6.826SerSer: 6.826 ± 4.801
2.73SerThr: 2.73 ± 2.075
2.73SerVal: 2.73 ± 1.399
0.0SerTrp: 0.0 ± 0.0
4.096SerTyr: 4.096 ± 0.968
0.0SerXaa: 0.0 ± 0.0
Thr
5.461ThrAla: 5.461 ± 2.349
0.0ThrCys: 0.0 ± 0.0
3.413ThrAsp: 3.413 ± 0.436
1.365ThrGlu: 1.365 ± 0.973
2.73ThrPhe: 2.73 ± 1.214
5.461ThrGly: 5.461 ± 1.723
2.048ThrHis: 2.048 ± 1.268
2.048ThrIle: 2.048 ± 0.507
3.413ThrLys: 3.413 ± 1.582
3.413ThrLeu: 3.413 ± 1.693
0.683ThrMet: 0.683 ± 0.423
2.048ThrAsn: 2.048 ± 1.636
4.096ThrPro: 4.096 ± 1.972
4.096ThrGln: 4.096 ± 1.377
2.048ThrArg: 2.048 ± 0.737
5.461ThrSer: 5.461 ± 2.799
2.73ThrThr: 2.73 ± 1.69
3.413ThrVal: 3.413 ± 1.44
0.683ThrTrp: 0.683 ± 0.666
2.048ThrTyr: 2.048 ± 1.095
0.0ThrXaa: 0.0 ± 0.0
Val
5.461ValAla: 5.461 ± 1.467
0.0ValCys: 0.0 ± 0.0
2.73ValAsp: 2.73 ± 1.214
1.365ValGlu: 1.365 ± 0.845
0.0ValPhe: 0.0 ± 0.0
2.048ValGly: 2.048 ± 0.861
0.683ValHis: 0.683 ± 0.866
2.73ValIle: 2.73 ± 0.955
2.048ValLys: 2.048 ± 1.717
1.365ValLeu: 1.365 ± 1.46
2.048ValMet: 2.048 ± 1.083
4.096ValAsn: 4.096 ± 1.651
3.413ValPro: 3.413 ± 2.113
5.461ValGln: 5.461 ± 1.245
2.048ValArg: 2.048 ± 1.132
4.778ValSer: 4.778 ± 2.093
6.143ValThr: 6.143 ± 0.989
4.096ValVal: 4.096 ± 1.092
1.365ValTrp: 1.365 ± 0.845
2.73ValTyr: 2.73 ± 1.063
0.0ValXaa: 0.0 ± 0.0
Trp
1.365TrpAla: 1.365 ± 0.561
0.0TrpCys: 0.0 ± 0.0
2.048TrpAsp: 2.048 ± 1.999
0.0TrpGlu: 0.0 ± 0.0
2.048TrpPhe: 2.048 ± 0.737
1.365TrpGly: 1.365 ± 0.7
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.365TrpPro: 1.365 ± 0.845
1.365TrpGln: 1.365 ± 0.7
0.0TrpArg: 0.0 ± 0.0
2.048TrpSer: 2.048 ± 0.507
2.048TrpThr: 2.048 ± 1.268
0.683TrpVal: 0.683 ± 0.423
0.0TrpTrp: 0.0 ± 0.0
1.365TrpTyr: 1.365 ± 0.685
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.413TyrAla: 3.413 ± 1.717
0.0TyrCys: 0.0 ± 0.0
4.778TyrAsp: 4.778 ± 2.216
2.048TyrGlu: 2.048 ± 1.157
2.048TyrPhe: 2.048 ± 1.157
6.143TyrGly: 6.143 ± 1.522
1.365TyrHis: 1.365 ± 0.561
1.365TyrIle: 1.365 ± 0.561
2.048TyrLys: 2.048 ± 0.737
4.778TyrLeu: 4.778 ± 1.53
2.048TyrMet: 2.048 ± 0.782
4.096TyrAsn: 4.096 ± 0.968
1.365TyrPro: 1.365 ± 0.561
2.048TyrGln: 2.048 ± 1.366
2.048TyrArg: 2.048 ± 0.737
4.778TyrSer: 4.778 ± 0.865
0.683TyrThr: 0.683 ± 0.73
2.73TyrVal: 2.73 ± 1.803
0.683TyrTrp: 0.683 ± 0.423
5.461TyrTyr: 5.461 ± 2.841
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1466 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski