Amino acid dipepetide frequency for Hespellia stercorisuis DSM 15480

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.156AlaAla: 7.156 ± 0.129	1.092AlaCys: 1.092 ± 0.031	4.773AlaAsp: 4.773 ± 0.073	5.728AlaGlu: 5.728 ± 0.075	3.004AlaPhe: 3.004 ± 0.054	6.198AlaGly: 6.198 ± 0.094	1.151AlaHis: 1.151 ± 0.028	5.172AlaIle: 5.172 ± 0.085	5.049AlaLys: 5.049 ± 0.065	6.794AlaLeu: 6.794 ± 0.087	2.445AlaMet: 2.445 ± 0.051	2.702AlaAsn: 2.702 ± 0.053	2.001AlaPro: 2.001 ± 0.042	2.448AlaGln: 2.448 ± 0.054	2.881AlaArg: 2.881 ± 0.057	3.92AlaSer: 3.92 ± 0.066	3.615AlaThr: 3.615 ± 0.069	6.316AlaVal: 6.316 ± 0.093	0.607AlaTrp: 0.607 ± 0.023	2.845AlaTyr: 2.845 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.037CysAla: 1.037 ± 0.031	0.235CysCys: 0.235 ± 0.015	0.835CysAsp: 0.835 ± 0.029	1.033CysGlu: 1.033 ± 0.03	0.615CysPhe: 0.615 ± 0.022	1.446CysGly: 1.446 ± 0.037	0.286CysHis: 0.286 ± 0.017	1.054CysIle: 1.054 ± 0.03	0.756CysLys: 0.756 ± 0.024	1.089CysLeu: 1.089 ± 0.032	0.448CysMet: 0.448 ± 0.02	0.533CysAsn: 0.533 ± 0.022	0.585CysPro: 0.585 ± 0.028	0.419CysGln: 0.419 ± 0.017	0.756CysArg: 0.756 ± 0.023	0.929CysSer: 0.929 ± 0.026	0.789CysThr: 0.789 ± 0.03	1.025CysVal: 1.025 ± 0.031	0.108CysTrp: 0.108 ± 0.009	0.578CysTyr: 0.578 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	4.45AspAla: 4.45 ± 0.07	0.827AspCys: 0.827 ± 0.028	2.988AspAsp: 2.988 ± 0.066	4.76AspGlu: 4.76 ± 0.072	2.569AspPhe: 2.569 ± 0.05	4.541AspGly: 4.541 ± 0.083	0.924AspHis: 0.924 ± 0.03	4.448AspIle: 4.448 ± 0.065	3.58AspLys: 3.58 ± 0.061	4.447AspLeu: 4.447 ± 0.059	1.933AspMet: 1.933 ± 0.039	2.304AspAsn: 2.304 ± 0.05	1.657AspPro: 1.657 ± 0.04	1.492AspGln: 1.492 ± 0.04	2.424AspArg: 2.424 ± 0.049	3.273AspSer: 3.273 ± 0.066	3.258AspThr: 3.258 ± 0.068	3.939AspVal: 3.939 ± 0.053	0.573AspTrp: 0.573 ± 0.025	2.742AspTyr: 2.742 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	5.327GluAla: 5.327 ± 0.071	0.888GluCys: 0.888 ± 0.028	4.313GluAsp: 4.313 ± 0.065	7.317GluGlu: 7.317 ± 0.107	2.542GluPhe: 2.542 ± 0.053	4.274GluGly: 4.274 ± 0.065	1.457GluHis: 1.457 ± 0.032	5.556GluIle: 5.556 ± 0.072	6.965GluLys: 6.965 ± 0.086	6.925GluLeu: 6.925 ± 0.075	2.664GluMet: 2.664 ± 0.047	4.157GluAsn: 4.157 ± 0.058	1.942GluPro: 1.942 ± 0.042	3.317GluGln: 3.317 ± 0.054	3.509GluArg: 3.509 ± 0.065	3.73GluSer: 3.73 ± 0.06	4.02GluThr: 4.02 ± 0.066	4.799GluVal: 4.799 ± 0.071	0.697GluTrp: 0.697 ± 0.025	3.204GluTyr: 3.204 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	3.029PheAla: 3.029 ± 0.052	0.708PheCys: 0.708 ± 0.027	2.478PheAsp: 2.478 ± 0.051	2.606PheGlu: 2.606 ± 0.051	1.667PhePhe: 1.667 ± 0.047	2.898PheGly: 2.898 ± 0.059	0.777PheHis: 0.777 ± 0.025	2.574PheIle: 2.574 ± 0.057	1.93PheLys: 1.93 ± 0.047	3.687PheLeu: 3.687 ± 0.074	1.103PheMet: 1.103 ± 0.031	1.472PheAsn: 1.472 ± 0.035	1.3PhePro: 1.3 ± 0.034	1.347PheGln: 1.347 ± 0.035	1.67PheArg: 1.67 ± 0.04	2.667PheSer: 2.667 ± 0.047	2.345PheThr: 2.345 ± 0.053	2.872PheVal: 2.872 ± 0.051	0.368PheTrp: 0.368 ± 0.019	1.624PheTyr: 1.624 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.139GlyAla: 5.139 ± 0.083	1.194GlyCys: 1.194 ± 0.032	3.559GlyAsp: 3.559 ± 0.055	4.802GlyGlu: 4.802 ± 0.07	2.971GlyPhe: 2.971 ± 0.052	5.006GlyGly: 5.006 ± 0.092	1.204GlyHis: 1.204 ± 0.033	6.024GlyIle: 6.024 ± 0.076	5.345GlyLys: 5.345 ± 0.062	5.671GlyLeu: 5.671 ± 0.072	2.47GlyMet: 2.47 ± 0.05	3.2GlyAsn: 3.2 ± 0.061	1.157GlyPro: 1.157 ± 0.034	2.126GlyGln: 2.126 ± 0.046	3.036GlyArg: 3.036 ± 0.062	4.102GlySer: 4.102 ± 0.066	4.605GlyThr: 4.605 ± 0.096	5.231GlyVal: 5.231 ± 0.077	0.678GlyTrp: 0.678 ± 0.026	3.167GlyTyr: 3.167 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.159HisAla: 1.159 ± 0.032	0.315HisCys: 0.315 ± 0.017	0.973HisAsp: 0.973 ± 0.03	1.113HisGlu: 1.113 ± 0.028	0.834HisPhe: 0.834 ± 0.024	1.25HisGly: 1.25 ± 0.035	0.399HisHis: 0.399 ± 0.019	1.365HisIle: 1.365 ± 0.03	1.007HisLys: 1.007 ± 0.032	1.516HisLeu: 1.516 ± 0.036	0.548HisMet: 0.548 ± 0.022	0.697HisAsn: 0.697 ± 0.023	0.83HisPro: 0.83 ± 0.028	0.558HisGln: 0.558 ± 0.024	0.773HisArg: 0.773 ± 0.023	0.969HisSer: 0.969 ± 0.03	1.054HisThr: 1.054 ± 0.025	1.084HisVal: 1.084 ± 0.031	0.137HisTrp: 0.137 ± 0.014	0.721HisTyr: 0.721 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.847IleAla: 5.847 ± 0.08	1.328IleCys: 1.328 ± 0.037	3.989IleAsp: 3.989 ± 0.064	4.926IleGlu: 4.926 ± 0.071	2.791IlePhe: 2.791 ± 0.06	5.128IleGly: 5.128 ± 0.077	1.331IleHis: 1.331 ± 0.034	4.808IleIle: 4.808 ± 0.092	3.995IleLys: 3.995 ± 0.058	6.661IleLeu: 6.661 ± 0.096	1.995IleMet: 1.995 ± 0.046	2.852IleAsn: 2.852 ± 0.058	3.107IlePro: 3.107 ± 0.052	2.443IleGln: 2.443 ± 0.045	3.634IleArg: 3.634 ± 0.059	4.764IleSer: 4.764 ± 0.068	4.265IleThr: 4.265 ± 0.072	5.027IleVal: 5.027 ± 0.084	0.616IleTrp: 0.616 ± 0.026	2.651IleTyr: 2.651 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.12LysAla: 5.12 ± 0.068	0.719LysCys: 0.719 ± 0.026	3.99LysAsp: 3.99 ± 0.062	6.56LysGlu: 6.56 ± 0.083	1.846LysPhe: 1.846 ± 0.043	3.953LysGly: 3.953 ± 0.057	1.04LysHis: 1.04 ± 0.028	4.794LysIle: 4.794 ± 0.06	6.313LysLys: 6.313 ± 0.091	5.421LysLeu: 5.421 ± 0.075	2.223LysMet: 2.223 ± 0.047	3.762LysAsn: 3.762 ± 0.06	1.944LysPro: 1.944 ± 0.042	2.522LysGln: 2.522 ± 0.051	3.147LysArg: 3.147 ± 0.065	3.71LysSer: 3.71 ± 0.053	4.031LysThr: 4.031 ± 0.059	4.41LysVal: 4.41 ± 0.061	0.628LysTrp: 0.628 ± 0.024	2.875LysTyr: 2.875 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	6.676LeuAla: 6.676 ± 0.077	1.39LeuCys: 1.39 ± 0.038	5.008LeuAsp: 5.008 ± 0.065	6.32LeuGlu: 6.32 ± 0.073	3.623LeuPhe: 3.623 ± 0.071	5.905LeuGly: 5.905 ± 0.069	1.548LeuHis: 1.548 ± 0.039	5.836LeuIle: 5.836 ± 0.073	5.893LeuLys: 5.893 ± 0.069	8.12LeuLeu: 8.12 ± 0.114	2.562LeuMet: 2.562 ± 0.047	3.765LeuAsn: 3.765 ± 0.059	3.277LeuPro: 3.277 ± 0.054	3.065LeuGln: 3.065 ± 0.055	3.733LeuArg: 3.733 ± 0.072	5.793LeuSer: 5.793 ± 0.072	5.095LeuThr: 5.095 ± 0.067	5.541LeuVal: 5.541 ± 0.075	0.713LeuTrp: 0.713 ± 0.026	3.169LeuTyr: 3.169 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	2.464MetAla: 2.464 ± 0.042	0.358MetCys: 0.358 ± 0.016	1.953MetAsp: 1.953 ± 0.04	2.562MetGlu: 2.562 ± 0.052	1.02MetPhe: 1.02 ± 0.03	2.061MetGly: 2.061 ± 0.042	0.465MetHis: 0.465 ± 0.017	2.259MetIle: 2.259 ± 0.044	2.613MetLys: 2.613 ± 0.048	2.732MetLeu: 2.732 ± 0.055	0.975MetMet: 0.975 ± 0.029	1.708MetAsn: 1.708 ± 0.041	1.127MetPro: 1.127 ± 0.034	1.189MetGln: 1.189 ± 0.036	1.267MetArg: 1.267 ± 0.031	1.901MetSer: 1.901 ± 0.036	1.838MetThr: 1.838 ± 0.033	1.969MetVal: 1.969 ± 0.042	0.213MetTrp: 0.213 ± 0.014	0.903MetTyr: 0.903 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.229AsnAla: 3.229 ± 0.054	0.635AsnCys: 0.635 ± 0.026	2.079AsnAsp: 2.079 ± 0.044	2.91AsnGlu: 2.91 ± 0.053	1.499AsnPhe: 1.499 ± 0.037	3.5AsnGly: 3.5 ± 0.062	0.91AsnHis: 0.91 ± 0.027	3.303AsnIle: 3.303 ± 0.059	2.663AsnLys: 2.663 ± 0.046	3.877AsnLeu: 3.877 ± 0.059	1.368AsnMet: 1.368 ± 0.028	1.818AsnAsn: 1.818 ± 0.042	2.047AsnPro: 2.047 ± 0.042	1.651AsnGln: 1.651 ± 0.039	2.107AsnArg: 2.107 ± 0.043	2.325AsnSer: 2.325 ± 0.05	2.446AsnThr: 2.446 ± 0.049	2.999AsnVal: 2.999 ± 0.053	0.436AsnTrp: 0.436 ± 0.018	1.854AsnTyr: 1.854 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	2.298ProAla: 2.298 ± 0.05	0.401ProCys: 0.401 ± 0.019	2.207ProAsp: 2.207 ± 0.043	3.201ProGlu: 3.201 ± 0.059	1.478ProPhe: 1.478 ± 0.034	2.137ProGly: 2.137 ± 0.044	0.54ProHis: 0.54 ± 0.023	2.072ProIle: 2.072 ± 0.039	1.893ProLys: 1.893 ± 0.043	2.56ProLeu: 2.56 ± 0.048	0.905ProMet: 0.905 ± 0.027	1.238ProAsn: 1.238 ± 0.03	0.73ProPro: 0.73 ± 0.026	1.048ProGln: 1.048 ± 0.027	1.011ProArg: 1.011 ± 0.028	1.738ProSer: 1.738 ± 0.04	1.688ProThr: 1.688 ± 0.039	2.765ProVal: 2.765 ± 0.047	0.273ProTrp: 0.273 ± 0.017	1.359ProTyr: 1.359 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.471GlnAla: 2.471 ± 0.05	0.395GlnCys: 0.395 ± 0.019	1.66GlnAsp: 1.66 ± 0.034	2.876GlnGlu: 2.876 ± 0.059	1.227GlnPhe: 1.227 ± 0.034	2.049GlnGly: 2.049 ± 0.041	0.518GlnHis: 0.518 ± 0.022	2.797GlnIle: 2.797 ± 0.052	2.876GlnLys: 2.876 ± 0.053	2.952GlnLeu: 2.952 ± 0.05	1.305GlnMet: 1.305 ± 0.032	1.751GlnAsn: 1.751 ± 0.037	0.941GlnPro: 0.941 ± 0.03	1.381GlnGln: 1.381 ± 0.043	1.49GlnArg: 1.49 ± 0.037	1.897GlnSer: 1.897 ± 0.044	1.88GlnThr: 1.88 ± 0.042	2.211GlnVal: 2.211 ± 0.042	0.307GlnTrp: 0.307 ± 0.014	1.397GlnTyr: 1.397 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.787ArgAla: 2.787 ± 0.054	0.575ArgCys: 0.575 ± 0.023	2.266ArgAsp: 2.266 ± 0.049	4.025ArgGlu: 4.025 ± 0.071	1.774ArgPhe: 1.774 ± 0.045	2.539ArgGly: 2.539 ± 0.047	0.746ArgHis: 0.746 ± 0.024	3.432ArgIle: 3.432 ± 0.062	3.531ArgLys: 3.531 ± 0.06	3.719ArgLeu: 3.719 ± 0.068	1.681ArgMet: 1.681 ± 0.042	2.017ArgAsn: 2.017 ± 0.04	1.247ArgPro: 1.247 ± 0.038	1.684ArgGln: 1.684 ± 0.041	2.243ArgArg: 2.243 ± 0.044	2.174ArgSer: 2.174 ± 0.04	2.332ArgThr: 2.332 ± 0.043	2.784ArgVal: 2.784 ± 0.048	0.376ArgTrp: 0.376 ± 0.016	1.887ArgTyr: 1.887 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.409SerAla: 4.409 ± 0.063	0.831SerCys: 0.831 ± 0.029	3.46SerAsp: 3.46 ± 0.056	4.047SerGlu: 4.047 ± 0.057	2.487SerPhe: 2.487 ± 0.051	5.11SerGly: 5.11 ± 0.081	1.029SerHis: 1.029 ± 0.028	4.048SerIle: 4.048 ± 0.051	3.46SerLys: 3.46 ± 0.052	4.829SerLeu: 4.829 ± 0.062	1.874SerMet: 1.874 ± 0.045	2.335SerAsn: 2.335 ± 0.058	1.625SerPro: 1.625 ± 0.033	1.873SerGln: 1.873 ± 0.042	2.714SerArg: 2.714 ± 0.049	3.49SerSer: 3.49 ± 0.069	3.118SerThr: 3.118 ± 0.056	4.411SerVal: 4.411 ± 0.073	0.554SerTrp: 0.554 ± 0.021	2.369SerTyr: 2.369 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	4.901ThrAla: 4.901 ± 0.098	0.685ThrCys: 0.685 ± 0.025	3.465ThrAsp: 3.465 ± 0.071	4.202ThrGlu: 4.202 ± 0.074	2.277ThrPhe: 2.277 ± 0.052	4.758ThrGly: 4.758 ± 0.083	0.863ThrHis: 0.863 ± 0.028	4.17ThrIle: 4.17 ± 0.067	3.475ThrLys: 3.475 ± 0.05	4.962ThrLeu: 4.962 ± 0.082	1.593ThrMet: 1.593 ± 0.035	2.173ThrAsn: 2.173 ± 0.055	2.087ThrPro: 2.087 ± 0.041	1.667ThrGln: 1.667 ± 0.038	2.016ThrArg: 2.016 ± 0.041	3.082ThrSer: 3.082 ± 0.063	3.264ThrThr: 3.264 ± 0.079	4.6ThrVal: 4.6 ± 0.079	0.515ThrTrp: 0.515 ± 0.022	2.214ThrTyr: 2.214 ± 0.056	0.001ThrXaa: 0.001 ± 0.001
Val	5.039ValAla: 5.039 ± 0.08	1.171ValCys: 1.171 ± 0.029	4.022ValAsp: 4.022 ± 0.058	4.914ValGlu: 4.914 ± 0.074	2.867ValPhe: 2.867 ± 0.055	4.427ValGly: 4.427 ± 0.075	1.113ValHis: 1.113 ± 0.032	5.06ValIle: 5.06 ± 0.071	4.681ValLys: 4.681 ± 0.065	6.639ValLeu: 6.639 ± 0.088	2.056ValMet: 2.056 ± 0.043	2.901ValAsn: 2.901 ± 0.043	2.465ValPro: 2.465 ± 0.044	2.205ValGln: 2.205 ± 0.043	3.042ValArg: 3.042 ± 0.055	4.758ValSer: 4.758 ± 0.065	4.458ValThr: 4.458 ± 0.09	5.009ValVal: 5.009 ± 0.081	0.662ValTrp: 0.662 ± 0.028	2.677ValTyr: 2.677 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.514TrpAla: 0.514 ± 0.021	0.166TrpCys: 0.166 ± 0.015	0.531TrpAsp: 0.531 ± 0.023	0.655TrpGlu: 0.655 ± 0.026	0.358TrpPhe: 0.358 ± 0.016	0.63TrpGly: 0.63 ± 0.025	0.144TrpHis: 0.144 ± 0.012	0.649TrpIle: 0.649 ± 0.022	0.71TrpLys: 0.71 ± 0.023	0.804TrpLeu: 0.804 ± 0.024	0.304TrpMet: 0.304 ± 0.016	0.533TrpAsn: 0.533 ± 0.022	0.184TrpPro: 0.184 ± 0.013	0.361TrpGln: 0.361 ± 0.017	0.385TrpArg: 0.385 ± 0.019	0.509TrpSer: 0.509 ± 0.024	0.454TrpThr: 0.454 ± 0.021	0.503TrpVal: 0.503 ± 0.021	0.092TrpTrp: 0.092 ± 0.009	0.386TrpTyr: 0.386 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.842TyrAla: 2.842 ± 0.047	0.642TyrCys: 0.642 ± 0.028	2.579TyrAsp: 2.579 ± 0.043	3.047TyrGlu: 3.047 ± 0.051	1.673TyrPhe: 1.673 ± 0.038	2.876TyrGly: 2.876 ± 0.051	0.856TyrHis: 0.856 ± 0.027	2.739TyrIle: 2.739 ± 0.048	2.274TyrLys: 2.274 ± 0.041	3.627TyrLeu: 3.627 ± 0.06	1.126TyrMet: 1.126 ± 0.027	1.739TyrAsn: 1.739 ± 0.039	1.289TyrPro: 1.289 ± 0.034	1.585TyrGln: 1.585 ± 0.038	1.982TyrArg: 1.982 ± 0.046	2.342TyrSer: 2.342 ± 0.05	2.417TyrThr: 2.417 ± 0.057	2.67TyrVal: 2.67 ± 0.048	0.319TyrTrp: 0.319 ± 0.018	1.816TyrTyr: 1.816 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.001

Statistics based on 4054 proteins (1281107 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---