Amino acid dipepetide frequency for Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.089AlaAla: 17.089 ± 0.235	0.948AlaCys: 0.948 ± 0.035	7.273AlaAsp: 7.273 ± 0.096	8.197AlaGlu: 8.197 ± 0.115	4.663AlaPhe: 4.663 ± 0.081	9.641AlaGly: 9.641 ± 0.118	2.13AlaHis: 2.13 ± 0.052	6.145AlaIle: 6.145 ± 0.097	3.751AlaLys: 3.751 ± 0.07	13.617AlaLeu: 13.617 ± 0.162	3.029AlaMet: 3.029 ± 0.075	2.504AlaAsn: 2.504 ± 0.067	6.194AlaPro: 6.194 ± 0.104	4.116AlaGln: 4.116 ± 0.07	8.047AlaArg: 8.047 ± 0.112	6.12AlaSer: 6.12 ± 0.084	5.944AlaThr: 5.944 ± 0.094	8.316AlaVal: 8.316 ± 0.122	1.289AlaTrp: 1.289 ± 0.041	2.789AlaTyr: 2.789 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.906CysAla: 0.906 ± 0.033	0.098CysCys: 0.098 ± 0.011	0.454CysAsp: 0.454 ± 0.024	0.447CysGlu: 0.447 ± 0.023	0.275CysPhe: 0.275 ± 0.018	0.837CysGly: 0.837 ± 0.032	0.207CysHis: 0.207 ± 0.014	0.281CysIle: 0.281 ± 0.02	0.149CysLys: 0.149 ± 0.016	0.907CysLeu: 0.907 ± 0.036	0.11CysMet: 0.11 ± 0.01	0.148CysAsn: 0.148 ± 0.015	0.442CysPro: 0.442 ± 0.022	0.23CysGln: 0.23 ± 0.018	0.61CysArg: 0.61 ± 0.032	0.383CysSer: 0.383 ± 0.019	0.396CysThr: 0.396 ± 0.02	0.497CysVal: 0.497 ± 0.025	0.067CysTrp: 0.067 ± 0.01	0.148CysTyr: 0.148 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.479AspAla: 6.479 ± 0.111	0.464AspCys: 0.464 ± 0.028	4.211AspAsp: 4.211 ± 0.097	4.233AspGlu: 4.233 ± 0.083	2.261AspPhe: 2.261 ± 0.063	5.35AspGly: 5.35 ± 0.09	1.512AspHis: 1.512 ± 0.042	3.514AspIle: 3.514 ± 0.069	1.729AspLys: 1.729 ± 0.047	7.038AspLeu: 7.038 ± 0.096	1.199AspMet: 1.199 ± 0.038	1.398AspAsn: 1.398 ± 0.043	3.811AspPro: 3.811 ± 0.063	2.316AspGln: 2.316 ± 0.053	5.444AspArg: 5.444 ± 0.089	2.317AspSer: 2.317 ± 0.058	2.922AspThr: 2.922 ± 0.064	4.135AspVal: 4.135 ± 0.072	0.921AspTrp: 0.921 ± 0.037	1.682AspTyr: 1.682 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	9.016GluAla: 9.016 ± 0.114	0.293GluCys: 0.293 ± 0.019	3.99GluAsp: 3.99 ± 0.078	4.549GluGlu: 4.549 ± 0.086	1.685GluPhe: 1.685 ± 0.044	5.898GluGly: 5.898 ± 0.083	0.936GluHis: 0.936 ± 0.037	3.566GluIle: 3.566 ± 0.079	2.427GluLys: 2.427 ± 0.064	4.763GluLeu: 4.763 ± 0.081	1.535GluMet: 1.535 ± 0.047	1.784GluAsn: 1.784 ± 0.051	2.419GluPro: 2.419 ± 0.057	1.965GluGln: 1.965 ± 0.049	5.173GluArg: 5.173 ± 0.089	2.439GluSer: 2.439 ± 0.06	4.549GluThr: 4.549 ± 0.07	4.103GluVal: 4.103 ± 0.064	0.721GluTrp: 0.721 ± 0.03	0.989GluTyr: 0.989 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.535PheAla: 4.535 ± 0.073	0.363PheCys: 0.363 ± 0.021	2.795PheAsp: 2.795 ± 0.062	2.346PheGlu: 2.346 ± 0.053	1.499PhePhe: 1.499 ± 0.048	3.749PheGly: 3.749 ± 0.071	0.679PheHis: 0.679 ± 0.029	1.702PheIle: 1.702 ± 0.051	0.872PheLys: 0.872 ± 0.034	3.766PheLeu: 3.766 ± 0.074	0.732PheMet: 0.732 ± 0.03	0.87PheAsn: 0.87 ± 0.028	1.633PhePro: 1.633 ± 0.053	0.905PheGln: 0.905 ± 0.033	2.192PheArg: 2.192 ± 0.048	2.443PheSer: 2.443 ± 0.057	2.076PheThr: 2.076 ± 0.049	2.807PheVal: 2.807 ± 0.061	0.52PheTrp: 0.52 ± 0.026	0.918PheTyr: 0.918 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	9.654GlyAla: 9.654 ± 0.129	0.667GlyCys: 0.667 ± 0.028	5.089GlyAsp: 5.089 ± 0.096	5.633GlyGlu: 5.633 ± 0.097	3.346GlyPhe: 3.346 ± 0.07	7.506GlyGly: 7.506 ± 0.124	1.8GlyHis: 1.8 ± 0.055	4.116GlyIle: 4.116 ± 0.071	2.775GlyLys: 2.775 ± 0.069	8.982GlyLeu: 8.982 ± 0.114	1.957GlyMet: 1.957 ± 0.051	1.833GlyAsn: 1.833 ± 0.049	3.905GlyPro: 3.905 ± 0.061	3.051GlyGln: 3.051 ± 0.065	6.187GlyArg: 6.187 ± 0.1	4.208GlySer: 4.208 ± 0.075	4.657GlyThr: 4.657 ± 0.082	6.159GlyVal: 6.159 ± 0.093	1.115GlyTrp: 1.115 ± 0.04	2.209GlyTyr: 2.209 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.013HisAla: 2.013 ± 0.053	0.196HisCys: 0.196 ± 0.016	1.179HisAsp: 1.179 ± 0.037	1.005HisGlu: 1.005 ± 0.033	0.814HisPhe: 0.814 ± 0.028	1.669HisGly: 1.669 ± 0.048	0.581HisHis: 0.581 ± 0.026	0.921HisIle: 0.921 ± 0.03	0.454HisLys: 0.454 ± 0.026	2.127HisLeu: 2.127 ± 0.059	0.378HisMet: 0.378 ± 0.021	0.399HisAsn: 0.399 ± 0.025	1.319HisPro: 1.319 ± 0.043	0.63HisGln: 0.63 ± 0.026	1.569HisArg: 1.569 ± 0.05	0.856HisSer: 0.856 ± 0.033	0.79HisThr: 0.79 ± 0.026	1.172HisVal: 1.172 ± 0.041	0.283HisTrp: 0.283 ± 0.019	0.557HisTyr: 0.557 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.752IleAla: 6.752 ± 0.088	0.47IleCys: 0.47 ± 0.028	4.162IleAsp: 4.162 ± 0.074	3.864IleGlu: 3.864 ± 0.065	1.747IlePhe: 1.747 ± 0.047	4.965IleGly: 4.965 ± 0.088	0.82IleHis: 0.82 ± 0.027	2.231IleIle: 2.231 ± 0.055	1.392IleLys: 1.392 ± 0.042	4.874IleLeu: 4.874 ± 0.08	0.803IleMet: 0.803 ± 0.034	1.306IleAsn: 1.306 ± 0.043	2.262IlePro: 2.262 ± 0.052	1.144IleGln: 1.144 ± 0.037	3.042IleArg: 3.042 ± 0.058	2.867IleSer: 2.867 ± 0.058	2.619IleThr: 2.619 ± 0.061	4.265IleVal: 4.265 ± 0.081	0.542IleTrp: 0.542 ± 0.031	1.117IleTyr: 1.117 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.115LysAla: 4.115 ± 0.077	0.137LysCys: 0.137 ± 0.012	1.893LysAsp: 1.893 ± 0.056	1.883LysGlu: 1.883 ± 0.057	0.794LysPhe: 0.794 ± 0.033	2.657LysGly: 2.657 ± 0.065	0.499LysHis: 0.499 ± 0.031	1.592LysIle: 1.592 ± 0.053	1.31LysLys: 1.31 ± 0.051	2.471LysLeu: 2.471 ± 0.058	0.718LysMet: 0.718 ± 0.029	0.716LysAsn: 0.716 ± 0.03	1.62LysPro: 1.62 ± 0.048	0.856LysGln: 0.856 ± 0.034	2.312LysArg: 2.312 ± 0.054	1.825LysSer: 1.825 ± 0.045	1.968LysThr: 1.968 ± 0.054	2.03LysVal: 2.03 ± 0.054	0.348LysTrp: 0.348 ± 0.02	0.563LysTyr: 0.563 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.814LeuAla: 12.814 ± 0.161	0.876LeuCys: 0.876 ± 0.03	6.266LeuAsp: 6.266 ± 0.092	5.591LeuGlu: 5.591 ± 0.081	3.922LeuPhe: 3.922 ± 0.081	8.339LeuGly: 8.339 ± 0.117	1.747LeuHis: 1.747 ± 0.047	5.545LeuIle: 5.545 ± 0.083	3.463LeuLys: 3.463 ± 0.072	9.935LeuLeu: 9.935 ± 0.146	2.254LeuMet: 2.254 ± 0.055	2.589LeuAsn: 2.589 ± 0.061	5.67LeuPro: 5.67 ± 0.086	2.611LeuGln: 2.611 ± 0.062	7.018LeuArg: 7.018 ± 0.1	8.003LeuSer: 8.003 ± 0.117	6.531LeuThr: 6.531 ± 0.088	6.761LeuVal: 6.761 ± 0.104	1.23LeuTrp: 1.23 ± 0.04	2.219LeuTyr: 2.219 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	3.105MetAla: 3.105 ± 0.06	0.113MetCys: 0.113 ± 0.012	1.055MetAsp: 1.055 ± 0.035	1.065MetGlu: 1.065 ± 0.035	0.581MetPhe: 0.581 ± 0.028	1.7MetGly: 1.7 ± 0.046	0.304MetHis: 0.304 ± 0.02	1.326MetIle: 1.326 ± 0.041	0.822MetLys: 0.822 ± 0.028	1.816MetLeu: 1.816 ± 0.051	0.697MetMet: 0.697 ± 0.03	0.581MetAsn: 0.581 ± 0.024	1.342MetPro: 1.342 ± 0.036	0.631MetGln: 0.631 ± 0.027	1.561MetArg: 1.561 ± 0.044	1.583MetSer: 1.583 ± 0.046	1.926MetThr: 1.926 ± 0.042	1.506MetVal: 1.506 ± 0.043	0.156MetTrp: 0.156 ± 0.014	0.208MetTyr: 0.208 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.938AsnAla: 2.938 ± 0.064	0.177AsnCys: 0.177 ± 0.014	1.503AsnAsp: 1.503 ± 0.049	1.282AsnGlu: 1.282 ± 0.04	0.903AsnPhe: 0.903 ± 0.035	2.133AsnGly: 2.133 ± 0.058	0.474AsnHis: 0.474 ± 0.021	1.203AsnIle: 1.203 ± 0.044	0.649AsnLys: 0.649 ± 0.028	2.239AsnLeu: 2.239 ± 0.059	0.501AsnMet: 0.501 ± 0.024	0.633AsnAsn: 0.633 ± 0.032	1.503AsnPro: 1.503 ± 0.048	0.718AsnGln: 0.718 ± 0.032	1.764AsnArg: 1.764 ± 0.043	1.118AsnSer: 1.118 ± 0.043	1.091AsnThr: 1.091 ± 0.04	1.777AsnVal: 1.777 ± 0.051	0.361AsnTrp: 0.361 ± 0.026	0.639AsnTyr: 0.639 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.621ProAla: 5.621 ± 0.09	0.354ProCys: 0.354 ± 0.021	3.776ProAsp: 3.776 ± 0.068	3.639ProGlu: 3.639 ± 0.064	2.154ProPhe: 2.154 ± 0.054	4.208ProGly: 4.208 ± 0.065	1.082ProHis: 1.082 ± 0.034	2.54ProIle: 2.54 ± 0.056	1.615ProLys: 1.615 ± 0.047	5.437ProLeu: 5.437 ± 0.076	1.106ProMet: 1.106 ± 0.035	1.303ProAsn: 1.303 ± 0.042	3.058ProPro: 3.058 ± 0.067	1.802ProGln: 1.802 ± 0.051	2.943ProArg: 2.943 ± 0.061	3.474ProSer: 3.474 ± 0.062	2.868ProThr: 2.868 ± 0.06	3.891ProVal: 3.891 ± 0.069	0.604ProTrp: 0.604 ± 0.034	1.208ProTyr: 1.208 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.767GlnAla: 3.767 ± 0.067	0.242GlnCys: 0.242 ± 0.017	1.722GlnAsp: 1.722 ± 0.043	1.793GlnGlu: 1.793 ± 0.046	1.117GlnPhe: 1.117 ± 0.035	2.526GlnGly: 2.526 ± 0.051	0.511GlnHis: 0.511 ± 0.028	1.824GlnIle: 1.824 ± 0.042	1.067GlnLys: 1.067 ± 0.036	2.914GlnLeu: 2.914 ± 0.066	0.819GlnMet: 0.819 ± 0.032	0.817GlnAsn: 0.817 ± 0.034	1.438GlnPro: 1.438 ± 0.044	1.079GlnGln: 1.079 ± 0.037	2.54GlnArg: 2.54 ± 0.058	2.103GlnSer: 2.103 ± 0.051	1.903GlnThr: 1.903 ± 0.048	2.141GlnVal: 2.141 ± 0.056	0.402GlnTrp: 0.402 ± 0.024	0.635GlnTyr: 0.635 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.775ArgAla: 7.775 ± 0.108	0.466ArgCys: 0.466 ± 0.025	3.924ArgAsp: 3.924 ± 0.073	4.381ArgGlu: 4.381 ± 0.074	3.076ArgPhe: 3.076 ± 0.068	4.836ArgGly: 4.836 ± 0.079	1.667ArgHis: 1.667 ± 0.049	3.582ArgIle: 3.582 ± 0.073	1.947ArgLys: 1.947 ± 0.051	8.736ArgLeu: 8.736 ± 0.123	1.629ArgMet: 1.629 ± 0.043	1.64ArgAsn: 1.64 ± 0.041	3.813ArgPro: 3.813 ± 0.066	2.934ArgGln: 2.934 ± 0.069	6.339ArgArg: 6.339 ± 0.126	3.783ArgSer: 3.783 ± 0.073	3.582ArgThr: 3.582 ± 0.063	4.457ArgVal: 4.457 ± 0.078	0.919ArgTrp: 0.919 ± 0.037	1.892ArgTyr: 1.892 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.539SerAla: 6.539 ± 0.092	0.432SerCys: 0.432 ± 0.023	3.351SerAsp: 3.351 ± 0.063	3.014SerGlu: 3.014 ± 0.066	2.426SerPhe: 2.426 ± 0.057	5.22SerGly: 5.22 ± 0.079	1.045SerHis: 1.045 ± 0.035	2.612SerIle: 2.612 ± 0.061	1.366SerLys: 1.366 ± 0.042	6.51SerLeu: 6.51 ± 0.098	1.276SerMet: 1.276 ± 0.037	1.223SerAsn: 1.223 ± 0.038	3.409SerPro: 3.409 ± 0.069	1.642SerGln: 1.642 ± 0.041	3.684SerArg: 3.684 ± 0.072	3.257SerSer: 3.257 ± 0.07	2.886SerThr: 2.886 ± 0.059	4.258SerVal: 4.258 ± 0.074	0.674SerTrp: 0.674 ± 0.03	1.354SerTyr: 1.354 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.07ThrAla: 7.07 ± 0.094	0.404ThrCys: 0.404 ± 0.022	3.633ThrAsp: 3.633 ± 0.073	3.313ThrGlu: 3.313 ± 0.064	2.069ThrPhe: 2.069 ± 0.048	5.166ThrGly: 5.166 ± 0.077	0.975ThrHis: 0.975 ± 0.033	2.998ThrIle: 2.998 ± 0.062	1.536ThrLys: 1.536 ± 0.039	6.451ThrLeu: 6.451 ± 0.095	1.051ThrMet: 1.051 ± 0.038	1.268ThrAsn: 1.268 ± 0.044	3.56ThrPro: 3.56 ± 0.063	1.558ThrGln: 1.558 ± 0.044	3.076ThrArg: 3.076 ± 0.06	2.861ThrSer: 2.861 ± 0.063	2.981ThrThr: 2.981 ± 0.063	4.452ThrVal: 4.452 ± 0.078	0.555ThrTrp: 0.555 ± 0.027	1.427ThrTyr: 1.427 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	7.902ValAla: 7.902 ± 0.1	0.554ValCys: 0.554 ± 0.027	4.452ValAsp: 4.452 ± 0.083	4.521ValGlu: 4.521 ± 0.064	2.705ValPhe: 2.705 ± 0.053	5.281ValGly: 5.281 ± 0.094	1.212ValHis: 1.212 ± 0.04	4.016ValIle: 4.016 ± 0.065	2.075ValLys: 2.075 ± 0.053	7.113ValLeu: 7.113 ± 0.105	1.632ValMet: 1.632 ± 0.051	1.707ValAsn: 1.707 ± 0.046	3.645ValPro: 3.645 ± 0.065	1.829ValGln: 1.829 ± 0.042	4.721ValArg: 4.721 ± 0.072	4.502ValSer: 4.502 ± 0.085	4.88ValThr: 4.88 ± 0.073	5.128ValVal: 5.128 ± 0.104	0.782ValTrp: 0.782 ± 0.029	1.451ValTyr: 1.451 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.226TrpAla: 1.226 ± 0.041	0.11TrpCys: 0.11 ± 0.012	0.558TrpAsp: 0.558 ± 0.029	0.611TrpGlu: 0.611 ± 0.028	0.451TrpPhe: 0.451 ± 0.024	0.89TrpGly: 0.89 ± 0.037	0.264TrpHis: 0.264 ± 0.019	0.584TrpIle: 0.584 ± 0.027	0.317TrpLys: 0.317 ± 0.018	1.351TrpLeu: 1.351 ± 0.04	0.272TrpMet: 0.272 ± 0.018	0.296TrpAsn: 0.296 ± 0.02	0.619TrpPro: 0.619 ± 0.03	0.549TrpGln: 0.549 ± 0.025	1.185TrpArg: 1.185 ± 0.04	0.904TrpSer: 0.904 ± 0.037	0.702TrpThr: 0.702 ± 0.029	0.735TrpVal: 0.735 ± 0.027	0.177TrpTrp: 0.177 ± 0.015	0.245TrpTyr: 0.245 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.485TyrAla: 2.485 ± 0.053	0.229TyrCys: 0.229 ± 0.016	1.652TyrAsp: 1.652 ± 0.046	1.431TyrGlu: 1.431 ± 0.042	0.914TyrPhe: 0.914 ± 0.033	2.28TyrGly: 2.28 ± 0.056	0.465TyrHis: 0.465 ± 0.023	0.948TyrIle: 0.948 ± 0.037	0.588TyrLys: 0.588 ± 0.027	2.338TyrLeu: 2.338 ± 0.054	0.378TyrMet: 0.378 ± 0.02	0.589TyrAsn: 0.589 ± 0.03	1.022TyrPro: 1.022 ± 0.036	0.797TyrGln: 0.797 ± 0.032	1.97TyrArg: 1.97 ± 0.054	1.133TyrSer: 1.133 ± 0.036	1.135TyrThr: 1.135 ± 0.041	1.515TyrVal: 1.515 ± 0.044	0.38TyrTrp: 0.38 ± 0.019	0.673TyrTyr: 0.673 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2687 proteins (870527 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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