Amino acid dipepetide frequency for Fusarium oxysporum (Fusarium vascular wilt)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.333AlaAla: 8.333 ± 0.049	1.158AlaCys: 1.158 ± 0.014	4.119AlaAsp: 4.119 ± 0.024	4.977AlaGlu: 4.977 ± 0.034	3.17AlaPhe: 3.17 ± 0.024	5.541AlaGly: 5.541 ± 0.032	1.687AlaHis: 1.687 ± 0.014	4.546AlaIle: 4.546 ± 0.027	4.113AlaLys: 4.113 ± 0.03	7.594AlaLeu: 7.594 ± 0.041	1.995AlaMet: 1.995 ± 0.016	2.945AlaAsn: 2.945 ± 0.019	4.528AlaPro: 4.528 ± 0.036	3.268AlaGln: 3.268 ± 0.024	4.497AlaArg: 4.497 ± 0.026	6.955AlaSer: 6.955 ± 0.036	5.212AlaThr: 5.212 ± 0.037	5.248AlaVal: 5.248 ± 0.03	1.238AlaTrp: 1.238 ± 0.013	2.186AlaTyr: 2.186 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.945CysAla: 0.945 ± 0.011	0.269CysCys: 0.269 ± 0.008	0.744CysAsp: 0.744 ± 0.011	0.664CysGlu: 0.664 ± 0.009	0.591CysPhe: 0.591 ± 0.009	0.983CysGly: 0.983 ± 0.015	0.36CysHis: 0.36 ± 0.007	0.797CysIle: 0.797 ± 0.011	0.604CysLys: 0.604 ± 0.011	1.334CysLeu: 1.334 ± 0.014	0.298CysMet: 0.298 ± 0.006	0.486CysAsn: 0.486 ± 0.008	0.685CysPro: 0.685 ± 0.012	0.514CysGln: 0.514 ± 0.008	0.796CysArg: 0.796 ± 0.011	0.984CysSer: 0.984 ± 0.012	0.748CysThr: 0.748 ± 0.009	0.85CysVal: 0.85 ± 0.012	0.24CysTrp: 0.24 ± 0.006	0.407CysTyr: 0.407 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.615AspAla: 4.615 ± 0.025	0.695AspCys: 0.695 ± 0.009	4.317AspAsp: 4.317 ± 0.03	4.542AspGlu: 4.542 ± 0.038	2.292AspPhe: 2.292 ± 0.017	4.094AspGly: 4.094 ± 0.027	1.292AspHis: 1.292 ± 0.014	3.3AspIle: 3.3 ± 0.022	2.695AspLys: 2.695 ± 0.023	5.148AspLeu: 5.148 ± 0.027	1.363AspMet: 1.363 ± 0.015	2.083AspAsn: 2.083 ± 0.017	3.289AspPro: 3.289 ± 0.023	1.973AspGln: 1.973 ± 0.018	2.977AspArg: 2.977 ± 0.024	4.142AspSer: 4.142 ± 0.025	3.062AspThr: 3.062 ± 0.023	3.699AspVal: 3.699 ± 0.025	0.965AspTrp: 0.965 ± 0.012	1.643AspTyr: 1.643 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.508GluAla: 5.508 ± 0.036	0.681GluCys: 0.681 ± 0.011	4.121GluAsp: 4.121 ± 0.033	5.176GluGlu: 5.176 ± 0.052	2.011GluPhe: 2.011 ± 0.016	3.645GluGly: 3.645 ± 0.026	1.437GluHis: 1.437 ± 0.012	3.098GluIle: 3.098 ± 0.021	3.636GluLys: 3.636 ± 0.031	5.189GluLeu: 5.189 ± 0.032	1.479GluMet: 1.479 ± 0.013	2.344GluAsn: 2.344 ± 0.016	2.939GluPro: 2.939 ± 0.029	2.42GluGln: 2.42 ± 0.018	3.716GluArg: 3.716 ± 0.029	4.296GluSer: 4.296 ± 0.026	3.798GluThr: 3.798 ± 0.031	3.588GluVal: 3.588 ± 0.024	0.941GluTrp: 0.941 ± 0.01	1.692GluTyr: 1.692 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.013PheAla: 3.013 ± 0.022	0.607PheCys: 0.607 ± 0.008	2.38PheAsp: 2.38 ± 0.018	2.217PheGlu: 2.217 ± 0.017	1.722PhePhe: 1.722 ± 0.019	2.918PheGly: 2.918 ± 0.026	0.932PheHis: 0.932 ± 0.009	2.015PheIle: 2.015 ± 0.017	1.661PheLys: 1.661 ± 0.015	3.517PheLeu: 3.517 ± 0.025	0.86PheMet: 0.86 ± 0.011	1.56PheAsn: 1.56 ± 0.015	1.93PhePro: 1.93 ± 0.017	1.456PheGln: 1.456 ± 0.013	1.93PheArg: 1.93 ± 0.017	3.002PheSer: 3.002 ± 0.024	2.256PheThr: 2.256 ± 0.016	2.426PheVal: 2.426 ± 0.018	0.701PheTrp: 0.701 ± 0.011	1.144PheTyr: 1.144 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.077GlyAla: 5.077 ± 0.03	0.944GlyCys: 0.944 ± 0.012	3.741GlyAsp: 3.741 ± 0.029	3.473GlyGlu: 3.473 ± 0.027	2.905GlyPhe: 2.905 ± 0.024	5.324GlyGly: 5.324 ± 0.049	1.725GlyHis: 1.725 ± 0.014	3.737GlyIle: 3.737 ± 0.024	3.458GlyLys: 3.458 ± 0.026	6.135GlyLeu: 6.135 ± 0.037	1.577GlyMet: 1.577 ± 0.015	2.684GlyAsn: 2.684 ± 0.024	3.265GlyPro: 3.265 ± 0.026	2.59GlyGln: 2.59 ± 0.021	3.916GlyArg: 3.916 ± 0.025	5.644GlySer: 5.644 ± 0.036	4.03GlyThr: 4.03 ± 0.035	4.224GlyVal: 4.224 ± 0.03	1.239GlyTrp: 1.239 ± 0.014	2.2GlyTyr: 2.2 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.743HisAla: 1.743 ± 0.016	0.344HisCys: 0.344 ± 0.007	1.415HisAsp: 1.415 ± 0.015	1.391HisGlu: 1.391 ± 0.014	0.952HisPhe: 0.952 ± 0.011	1.745HisGly: 1.745 ± 0.016	0.834HisHis: 0.834 ± 0.012	1.296HisIle: 1.296 ± 0.013	0.97HisLys: 0.97 ± 0.013	2.258HisLeu: 2.258 ± 0.02	0.518HisMet: 0.518 ± 0.009	0.874HisAsn: 0.874 ± 0.01	1.545HisPro: 1.545 ± 0.017	1.008HisGln: 1.008 ± 0.012	1.476HisArg: 1.476 ± 0.013	1.752HisSer: 1.752 ± 0.017	1.213HisThr: 1.213 ± 0.012	1.446HisVal: 1.446 ± 0.013	0.376HisTrp: 0.376 ± 0.007	0.726HisTyr: 0.726 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.372IleAla: 4.372 ± 0.027	0.823IleCys: 0.823 ± 0.011	3.066IleAsp: 3.066 ± 0.02	3.082IleGlu: 3.082 ± 0.022	2.105IlePhe: 2.105 ± 0.018	3.385IleGly: 3.385 ± 0.026	1.276IleHis: 1.276 ± 0.013	2.822IleIle: 2.822 ± 0.024	2.391IleLys: 2.391 ± 0.02	4.717IleLeu: 4.717 ± 0.027	1.117IleMet: 1.117 ± 0.013	1.993IleAsn: 1.993 ± 0.015	3.101IlePro: 3.101 ± 0.022	2.022IleGln: 2.022 ± 0.015	2.876IleArg: 2.876 ± 0.022	4.02IleSer: 4.02 ± 0.026	3.057IleThr: 3.057 ± 0.027	3.302IleVal: 3.302 ± 0.022	0.86IleTrp: 0.86 ± 0.011	1.505IleTyr: 1.505 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.374LysAla: 4.374 ± 0.027	0.586LysCys: 0.586 ± 0.01	3.069LysAsp: 3.069 ± 0.02	3.399LysGlu: 3.399 ± 0.031	1.542LysPhe: 1.542 ± 0.014	3.088LysGly: 3.088 ± 0.025	1.198LysHis: 1.198 ± 0.012	2.356LysIle: 2.356 ± 0.02	3.336LysLys: 3.336 ± 0.032	4.224LysLeu: 4.224 ± 0.026	1.051LysMet: 1.051 ± 0.014	1.891LysAsn: 1.891 ± 0.018	2.866LysPro: 2.866 ± 0.024	1.885LysGln: 1.885 ± 0.016	3.269LysArg: 3.269 ± 0.027	3.572LysSer: 3.572 ± 0.028	3.075LysThr: 3.075 ± 0.024	2.922LysVal: 2.922 ± 0.022	0.751LysTrp: 0.751 ± 0.009	1.425LysTyr: 1.425 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.699LeuAla: 7.699 ± 0.037	1.267LeuCys: 1.267 ± 0.013	5.258LeuAsp: 5.258 ± 0.031	5.553LeuGlu: 5.553 ± 0.035	3.423LeuPhe: 3.423 ± 0.021	5.96LeuGly: 5.96 ± 0.036	2.195LeuHis: 2.195 ± 0.019	4.218LeuIle: 4.218 ± 0.029	4.29LeuLys: 4.29 ± 0.026	8.156LeuLeu: 8.156 ± 0.044	1.876LeuMet: 1.876 ± 0.015	3.235LeuAsn: 3.235 ± 0.021	5.273LeuPro: 5.273 ± 0.029	3.762LeuGln: 3.762 ± 0.026	5.449LeuArg: 5.449 ± 0.033	7.161LeuSer: 7.161 ± 0.034	4.858LeuThr: 4.858 ± 0.029	5.465LeuVal: 5.465 ± 0.03	1.282LeuTrp: 1.282 ± 0.015	2.392LeuTyr: 2.392 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.309MetAla: 2.309 ± 0.017	0.266MetCys: 0.266 ± 0.006	1.266MetAsp: 1.266 ± 0.013	1.276MetGlu: 1.276 ± 0.012	0.788MetPhe: 0.788 ± 0.01	1.506MetGly: 1.506 ± 0.015	0.496MetHis: 0.496 ± 0.008	1.11MetIle: 1.11 ± 0.013	1.077MetLys: 1.077 ± 0.011	1.872MetLeu: 1.872 ± 0.017	0.621MetMet: 0.621 ± 0.01	0.847MetAsn: 0.847 ± 0.012	1.317MetPro: 1.317 ± 0.013	0.855MetGln: 0.855 ± 0.01	1.208MetArg: 1.208 ± 0.011	1.992MetSer: 1.992 ± 0.017	1.375MetThr: 1.375 ± 0.013	1.357MetVal: 1.357 ± 0.014	0.275MetTrp: 0.275 ± 0.006	0.536MetTyr: 0.536 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.087AsnAla: 3.087 ± 0.019	0.513AsnCys: 0.513 ± 0.008	2.128AsnAsp: 2.128 ± 0.018	2.123AsnGlu: 2.123 ± 0.018	1.426AsnPhe: 1.426 ± 0.013	3.049AsnGly: 3.049 ± 0.027	0.879AsnHis: 0.879 ± 0.01	2.171AsnIle: 2.171 ± 0.017	1.777AsnLys: 1.777 ± 0.015	3.352AsnLeu: 3.352 ± 0.022	0.931AsnMet: 0.931 ± 0.013	1.634AsnAsn: 1.634 ± 0.017	2.408AsnPro: 2.408 ± 0.017	1.4AsnGln: 1.4 ± 0.014	1.966AsnArg: 1.966 ± 0.017	2.836AsnSer: 2.836 ± 0.022	2.292AsnThr: 2.292 ± 0.019	2.324AsnVal: 2.324 ± 0.021	0.644AsnTrp: 0.644 ± 0.01	1.085AsnTyr: 1.085 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.741ProAla: 4.741 ± 0.037	0.563ProCys: 0.563 ± 0.007	3.28ProAsp: 3.28 ± 0.022	3.99ProGlu: 3.99 ± 0.025	2.092ProPhe: 2.092 ± 0.017	3.923ProGly: 3.923 ± 0.042	1.246ProHis: 1.246 ± 0.014	2.571ProIle: 2.571 ± 0.018	2.784ProLys: 2.784 ± 0.025	4.506ProLeu: 4.506 ± 0.026	1.102ProMet: 1.102 ± 0.014	2.196ProAsn: 2.196 ± 0.018	4.446ProPro: 4.446 ± 0.057	2.426ProGln: 2.426 ± 0.024	3.198ProArg: 3.198 ± 0.023	5.499ProSer: 5.499 ± 0.038	3.786ProThr: 3.786 ± 0.028	3.551ProVal: 3.551 ± 0.024	0.818ProTrp: 0.818 ± 0.011	1.516ProTyr: 1.516 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.46GlnAla: 3.46 ± 0.025	0.473GlnCys: 0.473 ± 0.009	2.271GlnAsp: 2.271 ± 0.017	2.459GlnGlu: 2.459 ± 0.021	1.298GlnPhe: 1.298 ± 0.012	2.531GlnGly: 2.531 ± 0.022	1.059GlnHis: 1.059 ± 0.013	1.895GlnIle: 1.895 ± 0.017	1.964GlnLys: 1.964 ± 0.016	3.434GlnLeu: 3.434 ± 0.027	0.89GlnMet: 0.89 ± 0.012	1.585GlnAsn: 1.585 ± 0.017	2.54GlnPro: 2.54 ± 0.027	2.329GlnGln: 2.329 ± 0.04	2.523GlnArg: 2.523 ± 0.02	3.009GlnSer: 3.009 ± 0.024	2.309GlnThr: 2.309 ± 0.019	2.269GlnVal: 2.269 ± 0.019	0.623GlnTrp: 0.623 ± 0.008	1.16GlnTyr: 1.16 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.28ArgAla: 4.28 ± 0.026	0.748ArgCys: 0.748 ± 0.01	3.37ArgAsp: 3.37 ± 0.029	3.565ArgGlu: 3.565 ± 0.028	2.134ArgPhe: 2.134 ± 0.018	3.495ArgGly: 3.495 ± 0.026	1.526ArgHis: 1.526 ± 0.015	2.868ArgIle: 2.868 ± 0.021	3.282ArgLys: 3.282 ± 0.022	5.362ArgLeu: 5.362 ± 0.028	1.277ArgMet: 1.277 ± 0.012	2.253ArgAsn: 2.253 ± 0.017	3.288ArgPro: 3.288 ± 0.025	2.555ArgGln: 2.555 ± 0.024	4.73ArgArg: 4.73 ± 0.04	4.43ArgSer: 4.43 ± 0.032	3.099ArgThr: 3.099 ± 0.019	3.275ArgVal: 3.275 ± 0.023	0.98ArgTrp: 0.98 ± 0.012	1.687ArgTyr: 1.687 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.147SerAla: 6.147 ± 0.035	0.972SerCys: 0.972 ± 0.012	4.346SerAsp: 4.346 ± 0.022	4.184SerGlu: 4.184 ± 0.023	3.102SerPhe: 3.102 ± 0.02	5.427SerGly: 5.427 ± 0.038	1.935SerHis: 1.935 ± 0.017	4.192SerIle: 4.192 ± 0.027	3.811SerLys: 3.811 ± 0.027	7.124SerLeu: 7.124 ± 0.037	1.758SerMet: 1.758 ± 0.015	3.013SerAsn: 3.013 ± 0.022	5.048SerPro: 5.048 ± 0.036	3.296SerGln: 3.296 ± 0.024	4.742SerArg: 4.742 ± 0.037	8.06SerSer: 8.06 ± 0.055	5.325SerThr: 5.325 ± 0.031	4.541SerVal: 4.541 ± 0.026	1.244SerTrp: 1.244 ± 0.012	2.123SerTyr: 2.123 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	5.125ThrAla: 5.125 ± 0.03	0.832ThrCys: 0.832 ± 0.012	2.922ThrAsp: 2.922 ± 0.021	3.331ThrGlu: 3.331 ± 0.024	2.296ThrPhe: 2.296 ± 0.018	4.202ThrGly: 4.202 ± 0.031	1.25ThrHis: 1.25 ± 0.012	3.367ThrIle: 3.367 ± 0.037	2.872ThrLys: 2.872 ± 0.023	5.194ThrLeu: 5.194 ± 0.027	1.222ThrMet: 1.222 ± 0.015	2.213ThrAsn: 2.213 ± 0.016	4.099ThrPro: 4.099 ± 0.035	2.169ThrGln: 2.169 ± 0.02	3.102ThrArg: 3.102 ± 0.021	5.204ThrSer: 5.204 ± 0.043	4.377ThrThr: 4.377 ± 0.06	3.815ThrVal: 3.815 ± 0.042	0.946ThrTrp: 0.946 ± 0.012	1.691ThrTyr: 1.691 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	5.118ValAla: 5.118 ± 0.029	0.879ValCys: 0.879 ± 0.013	3.709ValAsp: 3.709 ± 0.023	3.842ValGlu: 3.842 ± 0.027	2.563ValPhe: 2.563 ± 0.02	3.924ValGly: 3.924 ± 0.029	1.368ValHis: 1.368 ± 0.015	3.205ValIle: 3.205 ± 0.022	3.049ValLys: 3.049 ± 0.024	5.528ValLeu: 5.528 ± 0.028	1.361ValMet: 1.361 ± 0.011	2.288ValAsn: 2.288 ± 0.019	3.516ValPro: 3.516 ± 0.021	2.386ValGln: 2.386 ± 0.018	3.206ValArg: 3.206 ± 0.02	4.638ValSer: 4.638 ± 0.025	3.689ValThr: 3.689 ± 0.04	4.282ValVal: 4.282 ± 0.031	0.892ValTrp: 0.892 ± 0.011	1.782ValTyr: 1.782 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.23TrpAla: 1.23 ± 0.013	0.22TrpCys: 0.22 ± 0.006	0.96TrpAsp: 0.96 ± 0.014	0.887TrpGlu: 0.887 ± 0.012	0.619TrpPhe: 0.619 ± 0.01	1.017TrpGly: 1.017 ± 0.013	0.393TrpHis: 0.393 ± 0.008	0.875TrpIle: 0.875 ± 0.011	0.899TrpLys: 0.899 ± 0.011	1.463TrpLeu: 1.463 ± 0.014	0.394TrpMet: 0.394 ± 0.007	0.7TrpAsn: 0.7 ± 0.01	0.677TrpPro: 0.677 ± 0.009	0.618TrpGln: 0.618 ± 0.009	0.966TrpArg: 0.966 ± 0.011	1.142TrpSer: 1.142 ± 0.014	1.008TrpThr: 1.008 ± 0.012	0.965TrpVal: 0.965 ± 0.011	0.31TrpTrp: 0.31 ± 0.007	0.49TrpTyr: 0.49 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.133TyrAla: 2.133 ± 0.018	0.456TyrCys: 0.456 ± 0.008	1.704TyrAsp: 1.704 ± 0.015	1.584TyrGlu: 1.584 ± 0.016	1.215TyrPhe: 1.215 ± 0.015	2.132TyrGly: 2.132 ± 0.02	0.796TyrHis: 0.796 ± 0.012	1.451TyrIle: 1.451 ± 0.015	1.211TyrLys: 1.211 ± 0.013	2.664TyrLeu: 2.664 ± 0.02	0.658TyrMet: 0.658 ± 0.009	1.2TyrAsn: 1.2 ± 0.014	1.477TyrPro: 1.477 ± 0.016	1.149TyrGln: 1.149 ± 0.014	1.663TyrArg: 1.663 ± 0.015	2.053TyrSer: 2.053 ± 0.018	1.657TyrThr: 1.657 ± 0.017	1.679TyrVal: 1.679 ± 0.015	0.51TyrTrp: 0.51 ± 0.008	0.96TyrTyr: 0.96 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 18061 proteins (8091687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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