Amino acid dipepetide frequency for Sanxia tombus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.979AlaAla: 2.979 ± 1.231
0.0AlaCys: 0.0 ± 0.0
2.979AlaAsp: 2.979 ± 2.532
0.993AlaGlu: 0.993 ± 0.609
3.972AlaPhe: 3.972 ± 1.377
2.979AlaGly: 2.979 ± 2.539
1.986AlaHis: 1.986 ± 0.48
2.979AlaIle: 2.979 ± 1.826
5.958AlaLys: 5.958 ± 2.461
3.972AlaLeu: 3.972 ± 2.435
0.0AlaMet: 0.0 ± 0.0
5.958AlaAsn: 5.958 ± 1.399
7.944AlaPro: 7.944 ± 1.699
2.979AlaGln: 2.979 ± 1.975
1.986AlaArg: 1.986 ± 1.688
8.937AlaSer: 8.937 ± 2.488
0.993AlaThr: 0.993 ± 0.844
3.972AlaVal: 3.972 ± 0.96
1.986AlaTrp: 1.986 ± 1.472
0.993AlaTyr: 0.993 ± 0.844
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.993CysCys: 0.993 ± 1.362
0.993CysAsp: 0.993 ± 0.609
0.993CysGlu: 0.993 ± 0.609
0.993CysPhe: 0.993 ± 0.609
0.993CysGly: 0.993 ± 0.609
0.993CysHis: 0.993 ± 0.609
0.0CysIle: 0.0 ± 0.0
0.993CysLys: 0.993 ± 0.609
0.993CysLeu: 0.993 ± 1.362
0.993CysMet: 0.993 ± 0.609
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.986CysGln: 1.986 ± 1.217
1.986CysArg: 1.986 ± 0.48
2.979CysSer: 2.979 ± 2.539
0.0CysThr: 0.0 ± 0.0
1.986CysVal: 1.986 ± 1.217
0.0CysTrp: 0.0 ± 0.0
1.986CysTyr: 1.986 ± 1.246
0.0CysXaa: 0.0 ± 0.0
Asp
1.986AspAla: 1.986 ± 1.246
1.986AspCys: 1.986 ± 1.246
0.993AspAsp: 0.993 ± 0.609
0.993AspGlu: 0.993 ± 0.609
1.986AspPhe: 1.986 ± 0.48
2.979AspGly: 2.979 ± 1.975
0.993AspHis: 0.993 ± 0.609
2.979AspIle: 2.979 ± 1.826
0.993AspLys: 0.993 ± 0.609
8.937AspLeu: 8.937 ± 3.011
0.993AspMet: 0.993 ± 0.609
0.993AspAsn: 0.993 ± 0.844
4.965AspPro: 4.965 ± 3.413
3.972AspGln: 3.972 ± 0.775
0.993AspArg: 0.993 ± 0.844
0.993AspSer: 0.993 ± 0.844
0.0AspThr: 0.0 ± 0.0
1.986AspVal: 1.986 ± 0.48
0.993AspTrp: 0.993 ± 1.362
2.979AspTyr: 2.979 ± 2.532
0.0AspXaa: 0.0 ± 0.0
Glu
0.993GluAla: 0.993 ± 0.844
0.993GluCys: 0.993 ± 0.609
4.965GluAsp: 4.965 ± 1.797
0.0GluGlu: 0.0 ± 0.0
1.986GluPhe: 1.986 ± 1.217
5.958GluGly: 5.958 ± 0.328
0.993GluHis: 0.993 ± 0.609
3.972GluIle: 3.972 ± 2.055
4.965GluLys: 4.965 ± 1.797
4.965GluLeu: 4.965 ± 1.666
0.993GluMet: 0.993 ± 0.609
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
3.972GluGln: 3.972 ± 2.435
2.979GluArg: 2.979 ± 1.826
4.965GluSer: 4.965 ± 1.797
2.979GluThr: 2.979 ± 1.231
2.979GluVal: 2.979 ± 0.7
0.0GluTrp: 0.0 ± 0.0
0.993GluTyr: 0.993 ± 0.844
0.0GluXaa: 0.0 ± 0.0
Phe
3.972PheAla: 3.972 ± 1.377
1.986PheCys: 1.986 ± 1.217
2.979PheAsp: 2.979 ± 0.7
2.979PheGlu: 2.979 ± 0.7
1.986PhePhe: 1.986 ± 1.688
2.979PheGly: 2.979 ± 1.826
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
0.993PheLys: 0.993 ± 0.609
0.993PheLeu: 0.993 ± 1.362
0.0PheMet: 0.0 ± 0.0
2.979PheAsn: 2.979 ± 1.231
3.972PhePro: 3.972 ± 1.22
2.979PheGln: 2.979 ± 0.7
1.986PheArg: 1.986 ± 0.48
5.958PheSer: 5.958 ± 0.328
5.958PheThr: 5.958 ± 3.73
3.972PheVal: 3.972 ± 0.775
1.986PheTrp: 1.986 ± 1.246
3.972PheTyr: 3.972 ± 1.22
0.0PheXaa: 0.0 ± 0.0
Gly
2.979GlyAla: 2.979 ± 1.975
0.993GlyCys: 0.993 ± 0.609
3.972GlyAsp: 3.972 ± 2.435
4.965GlyGlu: 4.965 ± 1.666
3.972GlyPhe: 3.972 ± 0.96
3.972GlyGly: 3.972 ± 0.775
0.993GlyHis: 0.993 ± 1.362
4.965GlyIle: 4.965 ± 0.964
2.979GlyLys: 2.979 ± 1.826
6.951GlyLeu: 6.951 ± 1.69
2.979GlyMet: 2.979 ± 0.73
3.972GlyAsn: 3.972 ± 1.377
0.0GlyPro: 0.0 ± 0.0
2.979GlyGln: 2.979 ± 1.006
3.972GlyArg: 3.972 ± 1.781
4.965GlySer: 4.965 ± 0.795
3.972GlyThr: 3.972 ± 1.377
3.972GlyVal: 3.972 ± 1.22
0.993GlyTrp: 0.993 ± 0.609
4.965GlyTyr: 4.965 ± 1.034
0.0GlyXaa: 0.0 ± 0.0
His
0.993HisAla: 0.993 ± 0.844
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.993HisGlu: 0.993 ± 0.609
0.993HisPhe: 0.993 ± 0.609
0.993HisGly: 0.993 ± 0.609
0.993HisHis: 0.993 ± 0.609
0.993HisIle: 0.993 ± 1.362
0.993HisLys: 0.993 ± 1.362
0.993HisLeu: 0.993 ± 0.609
0.0HisMet: 0.0 ± 0.0
0.993HisAsn: 0.993 ± 0.609
0.0HisPro: 0.0 ± 0.0
1.986HisGln: 1.986 ± 1.217
0.993HisArg: 0.993 ± 0.844
1.986HisSer: 1.986 ± 1.217
0.993HisThr: 0.993 ± 0.844
0.993HisVal: 0.993 ± 0.609
1.986HisTrp: 1.986 ± 1.217
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.986IleAla: 1.986 ± 1.217
0.0IleCys: 0.0 ± 0.0
3.972IleAsp: 3.972 ± 0.775
2.979IleGlu: 2.979 ± 1.231
4.965IlePhe: 4.965 ± 0.795
0.0IleGly: 0.0 ± 0.0
0.993IleHis: 0.993 ± 0.609
3.972IleIle: 3.972 ± 2.346
1.986IleLys: 1.986 ± 1.688
5.958IleLeu: 5.958 ± 0.328
0.0IleMet: 0.0 ± 0.0
1.986IleAsn: 1.986 ± 1.688
3.972IlePro: 3.972 ± 2.493
0.993IleGln: 0.993 ± 0.844
0.993IleArg: 0.993 ± 0.609
5.958IleSer: 5.958 ± 3.652
1.986IleThr: 1.986 ± 0.48
0.993IleVal: 0.993 ± 0.844
0.993IleTrp: 0.993 ± 0.844
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.986LysAla: 1.986 ± 1.217
0.993LysCys: 0.993 ± 0.609
0.993LysAsp: 0.993 ± 0.609
0.0LysGlu: 0.0 ± 0.0
2.979LysPhe: 2.979 ± 1.231
5.958LysGly: 5.958 ± 2.39
1.986LysHis: 1.986 ± 0.48
0.993LysIle: 0.993 ± 0.609
0.993LysLys: 0.993 ± 1.362
3.972LysLeu: 3.972 ± 0.96
0.993LysMet: 0.993 ± 0.609
0.993LysAsn: 0.993 ± 0.844
2.979LysPro: 2.979 ± 1.231
4.965LysGln: 4.965 ± 0.964
2.979LysArg: 2.979 ± 0.7
0.993LysSer: 0.993 ± 1.362
0.993LysThr: 0.993 ± 0.844
3.972LysVal: 3.972 ± 1.781
1.986LysTrp: 1.986 ± 0.48
4.965LysTyr: 4.965 ± 1.034
0.0LysXaa: 0.0 ± 0.0
Leu
6.951LeuAla: 6.951 ± 3.341
0.0LeuCys: 0.0 ± 0.0
5.958LeuAsp: 5.958 ± 2.013
7.944LeuGlu: 7.944 ± 1.699
6.951LeuPhe: 6.951 ± 2.229
4.965LeuGly: 4.965 ± 0.795
0.0LeuHis: 0.0 ± 0.0
3.972LeuIle: 3.972 ± 0.775
4.965LeuLys: 4.965 ± 1.797
5.958LeuLeu: 5.958 ± 2.019
3.972LeuMet: 3.972 ± 5.448
1.986LeuAsn: 1.986 ± 1.217
2.979LeuPro: 2.979 ± 1.412
4.965LeuGln: 4.965 ± 0.795
7.944LeuArg: 7.944 ± 1.132
5.958LeuSer: 5.958 ± 1.413
3.972LeuThr: 3.972 ± 1.377
2.979LeuVal: 2.979 ± 0.7
1.986LeuTrp: 1.986 ± 1.246
0.993LeuTyr: 0.993 ± 0.609
0.0LeuXaa: 0.0 ± 0.0
Met
1.986MetAla: 1.986 ± 1.688
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.979MetGlu: 2.979 ± 1.826
0.0MetPhe: 0.0 ± 0.0
2.979MetGly: 2.979 ± 1.006
0.993MetHis: 0.993 ± 0.609
0.0MetIle: 0.0 ± 0.0
0.993MetLys: 0.993 ± 0.844
1.986MetLeu: 1.986 ± 1.246
0.0MetMet: 0.0 ± 0.0
1.986MetAsn: 1.986 ± 1.217
0.993MetPro: 0.993 ± 0.609
1.986MetGln: 1.986 ± 1.688
2.979MetArg: 2.979 ± 2.539
2.979MetSer: 2.979 ± 2.539
0.993MetThr: 0.993 ± 0.844
5.958MetVal: 5.958 ± 1.413
0.0MetTrp: 0.0 ± 0.0
0.993MetTyr: 0.993 ± 0.844
0.0MetXaa: 0.0 ± 0.0
Asn
3.972AsnAla: 3.972 ± 2.055
1.986AsnCys: 1.986 ± 1.217
0.993AsnAsp: 0.993 ± 0.844
0.0AsnGlu: 0.0 ± 0.0
1.986AsnPhe: 1.986 ± 1.217
5.958AsnGly: 5.958 ± 1.44
0.0AsnHis: 0.0 ± 0.0
0.993AsnIle: 0.993 ± 0.609
2.979AsnLys: 2.979 ± 1.231
3.972AsnLeu: 3.972 ± 2.493
0.993AsnMet: 0.993 ± 1.362
4.965AsnAsn: 4.965 ± 1.034
2.979AsnPro: 2.979 ± 1.231
2.979AsnGln: 2.979 ± 2.532
0.993AsnArg: 0.993 ± 0.609
2.979AsnSer: 2.979 ± 1.231
2.979AsnThr: 2.979 ± 1.231
2.979AsnVal: 2.979 ± 1.231
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.979ProAla: 2.979 ± 1.231
0.0ProCys: 0.0 ± 0.0
1.986ProAsp: 1.986 ± 1.688
0.993ProGlu: 0.993 ± 0.609
0.0ProPhe: 0.0 ± 0.0
2.979ProGly: 2.979 ± 2.707
0.993ProHis: 0.993 ± 0.844
0.0ProIle: 0.0 ± 0.0
0.993ProLys: 0.993 ± 0.609
3.972ProLeu: 3.972 ± 1.377
3.972ProMet: 3.972 ± 0.775
0.993ProAsn: 0.993 ± 0.844
1.986ProPro: 1.986 ± 1.217
3.972ProGln: 3.972 ± 1.22
4.965ProArg: 4.965 ± 1.797
3.972ProSer: 3.972 ± 1.377
5.958ProThr: 5.958 ± 3.73
5.958ProVal: 5.958 ± 3.652
0.993ProTrp: 0.993 ± 0.844
2.979ProTyr: 2.979 ± 1.006
0.0ProXaa: 0.0 ± 0.0
Gln
1.986GlnAla: 1.986 ± 1.688
0.993GlnCys: 0.993 ± 0.609
1.986GlnAsp: 1.986 ± 1.688
3.972GlnGlu: 3.972 ± 1.22
2.979GlnPhe: 2.979 ± 0.7
1.986GlnGly: 1.986 ± 0.48
3.972GlnHis: 3.972 ± 1.781
2.979GlnIle: 2.979 ± 1.006
1.986GlnLys: 1.986 ± 0.48
3.972GlnLeu: 3.972 ± 0.96
2.979GlnMet: 2.979 ± 2.532
2.979GlnAsn: 2.979 ± 2.532
2.979GlnPro: 2.979 ± 1.412
3.972GlnGln: 3.972 ± 0.96
3.972GlnArg: 3.972 ± 1.781
3.972GlnSer: 3.972 ± 2.944
5.958GlnThr: 5.958 ± 1.399
3.972GlnVal: 3.972 ± 1.22
0.993GlnTrp: 0.993 ± 0.609
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.958ArgAla: 5.958 ± 2.39
2.979ArgCys: 2.979 ± 1.412
2.979ArgAsp: 2.979 ± 1.006
2.979ArgGlu: 2.979 ± 1.006
2.979ArgPhe: 2.979 ± 1.231
3.972ArgGly: 3.972 ± 1.22
0.993ArgHis: 0.993 ± 0.609
5.958ArgIle: 5.958 ± 2.461
1.986ArgLys: 1.986 ± 0.48
3.972ArgLeu: 3.972 ± 2.435
2.979ArgMet: 2.979 ± 0.7
3.972ArgAsn: 3.972 ± 2.493
0.0ArgPro: 0.0 ± 0.0
4.965ArgGln: 4.965 ± 0.964
1.986ArgArg: 1.986 ± 1.217
2.979ArgSer: 2.979 ± 1.412
1.986ArgThr: 1.986 ± 1.246
5.958ArgVal: 5.958 ± 2.785
0.0ArgTrp: 0.0 ± 0.0
3.972ArgTyr: 3.972 ± 1.781
0.0ArgXaa: 0.0 ± 0.0
Ser
6.951SerAla: 6.951 ± 2.26
1.986SerCys: 1.986 ± 1.217
1.986SerAsp: 1.986 ± 0.48
0.993SerGlu: 0.993 ± 0.609
3.972SerPhe: 3.972 ± 1.781
10.924SerGly: 10.924 ± 1.5
0.0SerHis: 0.0 ± 0.0
1.986SerIle: 1.986 ± 0.48
4.965SerLys: 4.965 ± 0.795
2.979SerLeu: 2.979 ± 2.539
0.993SerMet: 0.993 ± 1.463
4.965SerAsn: 4.965 ± 1.666
4.965SerPro: 4.965 ± 1.666
1.986SerGln: 1.986 ± 1.688
7.944SerArg: 7.944 ± 4.986
6.951SerSer: 6.951 ± 3.911
4.965SerThr: 4.965 ± 2.593
5.958SerVal: 5.958 ± 0.328
0.993SerTrp: 0.993 ± 0.609
1.986SerTyr: 1.986 ± 1.217
0.0SerXaa: 0.0 ± 0.0
Thr
7.944ThrAla: 7.944 ± 4.11
2.979ThrCys: 2.979 ± 2.707
0.0ThrAsp: 0.0 ± 0.0
2.979ThrGlu: 2.979 ± 0.7
1.986ThrPhe: 1.986 ± 0.48
3.972ThrGly: 3.972 ± 1.377
0.0ThrHis: 0.0 ± 0.0
2.979ThrIle: 2.979 ± 0.7
0.993ThrLys: 0.993 ± 0.609
3.972ThrLeu: 3.972 ± 1.377
1.986ThrMet: 1.986 ± 1.217
2.979ThrAsn: 2.979 ± 2.532
4.965ThrPro: 4.965 ± 0.795
0.993ThrGln: 0.993 ± 0.844
3.972ThrArg: 3.972 ± 1.22
5.958ThrSer: 5.958 ± 1.44
4.965ThrThr: 4.965 ± 4.219
2.979ThrVal: 2.979 ± 2.532
0.0ThrTrp: 0.0 ± 0.0
0.993ThrTyr: 0.993 ± 0.844
0.0ThrXaa: 0.0 ± 0.0
Val
6.951ValAla: 6.951 ± 1.452
0.993ValCys: 0.993 ± 0.609
3.972ValAsp: 3.972 ± 0.775
6.951ValGlu: 6.951 ± 1.894
4.965ValPhe: 4.965 ± 3.043
3.972ValGly: 3.972 ± 1.781
0.993ValHis: 0.993 ± 0.609
2.979ValIle: 2.979 ± 1.975
2.979ValLys: 2.979 ± 1.826
8.937ValLeu: 8.937 ± 2.737
0.993ValMet: 0.993 ± 0.565
0.993ValAsn: 0.993 ± 0.609
4.965ValPro: 4.965 ± 2.89
3.972ValGln: 3.972 ± 2.055
2.979ValArg: 2.979 ± 1.826
2.979ValSer: 2.979 ± 1.006
2.979ValThr: 2.979 ± 1.231
2.979ValVal: 2.979 ± 0.7
0.993ValTrp: 0.993 ± 0.609
0.993ValTyr: 0.993 ± 0.609
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.993TrpAsp: 0.993 ± 1.362
0.993TrpGlu: 0.993 ± 0.609
1.986TrpPhe: 1.986 ± 0.48
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.993TrpLys: 0.993 ± 1.362
6.951TrpLeu: 6.951 ± 2.26
0.993TrpMet: 0.993 ± 0.609
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.993TrpArg: 0.993 ± 0.609
0.0TrpSer: 0.0 ± 0.0
3.972TrpThr: 3.972 ± 1.22
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.993TyrAla: 0.993 ± 0.844
0.0TyrCys: 0.0 ± 0.0
0.993TyrAsp: 0.993 ± 0.844
3.972TyrGlu: 3.972 ± 0.96
0.993TyrPhe: 0.993 ± 1.362
0.993TyrGly: 0.993 ± 0.609
0.0TyrHis: 0.0 ± 0.0
1.986TyrIle: 1.986 ± 0.48
1.986TyrLys: 1.986 ± 1.217
0.993TyrLeu: 0.993 ± 0.609
2.979TyrMet: 2.979 ± 0.7
0.993TyrAsn: 0.993 ± 0.609
0.0TyrPro: 0.0 ± 0.0
1.986TyrGln: 1.986 ± 1.217
5.958TyrArg: 5.958 ± 0.328
2.979TyrSer: 2.979 ± 1.231
0.993TyrThr: 0.993 ± 0.609
3.972TyrVal: 3.972 ± 1.377
0.993TyrTrp: 0.993 ± 0.844
0.993TyrTyr: 0.993 ± 0.844
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1008 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski