Amino acid dipepetide frequency for Tortoise microvirus 93

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.876AlaAla: 8.876 ± 2.169
0.0AlaCys: 0.0 ± 0.0
6.657AlaAsp: 6.657 ± 2.309
5.178AlaGlu: 5.178 ± 1.724
5.178AlaPhe: 5.178 ± 1.493
10.355AlaGly: 10.355 ± 3.888
2.959AlaHis: 2.959 ± 1.367
5.917AlaIle: 5.917 ± 1.513
2.959AlaLys: 2.959 ± 1.654
4.438AlaLeu: 4.438 ± 1.756
0.74AlaMet: 0.74 ± 0.658
4.438AlaAsn: 4.438 ± 1.161
2.959AlaPro: 2.959 ± 1.134
2.959AlaGln: 2.959 ± 1.284
5.178AlaArg: 5.178 ± 1.565
2.219AlaSer: 2.219 ± 1.335
4.438AlaThr: 4.438 ± 3.24
2.959AlaVal: 2.959 ± 1.367
2.959AlaTrp: 2.959 ± 1.423
3.698AlaTyr: 3.698 ± 1.11
0.0AlaXaa: 0.0 ± 0.0
Cys
0.74CysAla: 0.74 ± 1.162
0.74CysCys: 0.74 ± 0.658
0.74CysAsp: 0.74 ± 0.658
0.74CysGlu: 0.74 ± 0.658
0.0CysPhe: 0.0 ± 0.0
0.74CysGly: 0.74 ± 0.658
0.74CysHis: 0.74 ± 0.658
0.74CysIle: 0.74 ± 0.658
1.479CysLys: 1.479 ± 0.61
1.479CysLeu: 1.479 ± 1.316
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.74CysPro: 0.74 ± 0.658
0.74CysGln: 0.74 ± 0.519
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.657AspAla: 6.657 ± 1.291
0.0AspCys: 0.0 ± 0.0
0.74AspAsp: 0.74 ± 0.658
2.959AspGlu: 2.959 ± 1.852
2.219AspPhe: 2.219 ± 0.547
0.74AspGly: 0.74 ± 0.519
0.74AspHis: 0.74 ± 0.658
2.959AspIle: 2.959 ± 1.367
1.479AspLys: 1.479 ± 0.61
9.615AspLeu: 9.615 ± 2.737
2.219AspMet: 2.219 ± 1.558
1.479AspAsn: 1.479 ± 0.673
2.959AspPro: 2.959 ± 1.43
5.178AspGln: 5.178 ± 1.472
1.479AspArg: 1.479 ± 1.084
2.959AspSer: 2.959 ± 0.704
1.479AspThr: 1.479 ± 0.673
2.959AspVal: 2.959 ± 1.367
0.0AspTrp: 0.0 ± 0.0
3.698AspTyr: 3.698 ± 1.999
0.0AspXaa: 0.0 ± 0.0
Glu
2.219GluAla: 2.219 ± 1.109
1.479GluCys: 1.479 ± 0.61
0.74GluAsp: 0.74 ± 0.956
4.438GluGlu: 4.438 ± 1.431
1.479GluPhe: 1.479 ± 0.61
2.959GluGly: 2.959 ± 2.595
0.74GluHis: 0.74 ± 0.519
5.178GluIle: 5.178 ± 3.477
3.698GluLys: 3.698 ± 1.271
2.219GluLeu: 2.219 ± 1.501
0.74GluMet: 0.74 ± 0.682
2.219GluAsn: 2.219 ± 0.547
1.479GluPro: 1.479 ± 1.619
4.438GluGln: 4.438 ± 0.753
11.095GluArg: 11.095 ± 4.307
4.438GluSer: 4.438 ± 1.434
1.479GluThr: 1.479 ± 0.936
3.698GluVal: 3.698 ± 1.296
0.74GluTrp: 0.74 ± 0.519
4.438GluTyr: 4.438 ± 1.133
0.0GluXaa: 0.0 ± 0.0
Phe
2.959PheAla: 2.959 ± 2.077
0.0PheCys: 0.0 ± 0.0
2.219PheAsp: 2.219 ± 0.99
0.74PheGlu: 0.74 ± 0.519
1.479PhePhe: 1.479 ± 1.039
2.959PheGly: 2.959 ± 2.077
1.479PheHis: 1.479 ± 1.039
2.219PheIle: 2.219 ± 0.923
2.219PheLys: 2.219 ± 1.252
0.0PheLeu: 0.0 ± 0.0
2.219PheMet: 2.219 ± 0.886
1.479PheAsn: 1.479 ± 0.802
1.479PhePro: 1.479 ± 1.316
1.479PheGln: 1.479 ± 1.298
2.219PheArg: 2.219 ± 1.158
2.959PheSer: 2.959 ± 0.704
3.698PheThr: 3.698 ± 1.476
2.219PheVal: 2.219 ± 1.173
1.479PheTrp: 1.479 ± 0.673
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.178GlyAla: 5.178 ± 2.369
0.0GlyCys: 0.0 ± 0.0
4.438GlyAsp: 4.438 ± 2.396
3.698GlyGlu: 3.698 ± 2.325
0.0GlyPhe: 0.0 ± 0.0
2.959GlyGly: 2.959 ± 1.078
2.959GlyHis: 2.959 ± 1.134
2.219GlyIle: 2.219 ± 0.99
3.698GlyLys: 3.698 ± 2.424
3.698GlyLeu: 3.698 ± 2.112
0.74GlyMet: 0.74 ± 0.519
2.219GlyAsn: 2.219 ± 0.99
2.219GlyPro: 2.219 ± 1.454
4.438GlyGln: 4.438 ± 1.434
2.959GlyArg: 2.959 ± 0.685
5.917GlySer: 5.917 ± 1.994
3.698GlyThr: 3.698 ± 1.648
2.219GlyVal: 2.219 ± 0.547
0.74GlyTrp: 0.74 ± 1.162
2.959GlyTyr: 2.959 ± 1.367
0.0GlyXaa: 0.0 ± 0.0
His
3.698HisAla: 3.698 ± 2.524
0.74HisCys: 0.74 ± 0.519
1.479HisAsp: 1.479 ± 1.039
2.219HisGlu: 2.219 ± 1.074
2.219HisPhe: 2.219 ± 1.558
1.479HisGly: 1.479 ± 1.039
0.0HisHis: 0.0 ± 0.0
1.479HisIle: 1.479 ± 0.673
2.219HisLys: 2.219 ± 0.923
2.219HisLeu: 2.219 ± 1.558
0.74HisMet: 0.74 ± 0.682
0.0HisAsn: 0.0 ± 0.0
0.74HisPro: 0.74 ± 0.658
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.219HisSer: 2.219 ± 1.173
0.0HisThr: 0.0 ± 0.0
2.219HisVal: 2.219 ± 1.158
0.0HisTrp: 0.0 ± 0.0
0.74HisTyr: 0.74 ± 0.658
0.0HisXaa: 0.0 ± 0.0
Ile
5.178IleAla: 5.178 ± 2.406
0.0IleCys: 0.0 ± 0.0
2.959IleAsp: 2.959 ± 1.007
2.219IleGlu: 2.219 ± 0.923
3.698IlePhe: 3.698 ± 1.851
2.219IleGly: 2.219 ± 0.547
0.74IleHis: 0.74 ± 0.519
3.698IleIle: 3.698 ± 1.731
2.959IleLys: 2.959 ± 1.007
2.959IleLeu: 2.959 ± 1.395
2.219IleMet: 2.219 ± 0.525
2.959IleAsn: 2.959 ± 1.346
5.178IlePro: 5.178 ± 1.323
3.698IleGln: 3.698 ± 2.011
2.959IleArg: 2.959 ± 1.654
4.438IleSer: 4.438 ± 1.133
4.438IleThr: 4.438 ± 1.095
1.479IleVal: 1.479 ± 1.039
0.0IleTrp: 0.0 ± 0.0
3.698IleTyr: 3.698 ± 0.839
0.0IleXaa: 0.0 ± 0.0
Lys
5.917LysAla: 5.917 ± 0.662
1.479LysCys: 1.479 ± 1.298
0.0LysAsp: 0.0 ± 0.0
2.959LysGlu: 2.959 ± 1.414
2.959LysPhe: 2.959 ± 1.367
1.479LysGly: 1.479 ± 0.61
0.0LysHis: 0.0 ± 0.0
7.396LysIle: 7.396 ± 2.546
1.479LysLys: 1.479 ± 0.802
3.698LysLeu: 3.698 ± 1.476
1.479LysMet: 1.479 ± 0.622
2.219LysAsn: 2.219 ± 0.923
1.479LysPro: 1.479 ± 0.802
4.438LysGln: 4.438 ± 0.994
5.178LysArg: 5.178 ± 2.017
2.959LysSer: 2.959 ± 1.411
2.219LysThr: 2.219 ± 1.158
1.479LysVal: 1.479 ± 0.61
0.74LysTrp: 0.74 ± 0.682
0.74LysTyr: 0.74 ± 0.658
0.0LysXaa: 0.0 ± 0.0
Leu
4.438LeuAla: 4.438 ± 2.019
0.0LeuCys: 0.0 ± 0.0
5.178LeuAsp: 5.178 ± 1.384
4.438LeuGlu: 4.438 ± 1.763
0.74LeuPhe: 0.74 ± 0.658
6.657LeuGly: 6.657 ± 1.65
1.479LeuHis: 1.479 ± 0.802
2.959LeuIle: 2.959 ± 1.497
5.178LeuLys: 5.178 ± 3.204
4.438LeuLeu: 4.438 ± 1.901
0.74LeuMet: 0.74 ± 0.658
4.438LeuAsn: 4.438 ± 0.961
4.438LeuPro: 4.438 ± 1.795
7.396LeuGln: 7.396 ± 1.651
9.615LeuArg: 9.615 ± 2.864
8.136LeuSer: 8.136 ± 2.259
5.178LeuThr: 5.178 ± 1.58
4.438LeuVal: 4.438 ± 1.751
0.0LeuTrp: 0.0 ± 0.0
2.219LeuTyr: 2.219 ± 1.517
0.0LeuXaa: 0.0 ± 0.0
Met
0.74MetAla: 0.74 ± 0.519
0.74MetCys: 0.74 ± 0.658
0.0MetAsp: 0.0 ± 0.0
0.74MetGlu: 0.74 ± 0.682
0.0MetPhe: 0.0 ± 0.0
0.74MetGly: 0.74 ± 0.519
0.74MetHis: 0.74 ± 0.519
0.0MetIle: 0.0 ± 0.0
2.219MetLys: 2.219 ± 0.547
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
5.178MetPro: 5.178 ± 1.323
0.74MetGln: 0.74 ± 0.682
2.219MetArg: 2.219 ± 1.109
2.219MetSer: 2.219 ± 0.923
0.74MetThr: 0.74 ± 0.658
0.74MetVal: 0.74 ± 0.519
0.0MetTrp: 0.0 ± 0.0
1.479MetTyr: 1.479 ± 0.802
0.0MetXaa: 0.0 ± 0.0
Asn
6.657AsnAla: 6.657 ± 1.025
0.74AsnCys: 0.74 ± 0.658
3.698AsnAsp: 3.698 ± 1.61
3.698AsnGlu: 3.698 ± 2.704
2.959AsnPhe: 2.959 ± 1.007
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
2.219AsnIle: 2.219 ± 0.892
1.479AsnLys: 1.479 ± 0.802
5.178AsnLeu: 5.178 ± 1.925
0.0AsnMet: 0.0 ± 0.0
5.178AsnAsn: 5.178 ± 1.995
4.438AsnPro: 4.438 ± 1.395
0.0AsnGln: 0.0 ± 0.0
3.698AsnArg: 3.698 ± 1.11
3.698AsnSer: 3.698 ± 1.262
2.959AsnThr: 2.959 ± 1.963
2.219AsnVal: 2.219 ± 0.99
1.479AsnTrp: 1.479 ± 1.039
2.219AsnTyr: 2.219 ± 1.298
0.0AsnXaa: 0.0 ± 0.0
Pro
5.917ProAla: 5.917 ± 0.662
2.219ProCys: 2.219 ± 1.974
4.438ProAsp: 4.438 ± 2.59
2.219ProGlu: 2.219 ± 0.923
2.219ProPhe: 2.219 ± 0.923
2.219ProGly: 2.219 ± 1.109
1.479ProHis: 1.479 ± 0.61
4.438ProIle: 4.438 ± 1.554
2.959ProLys: 2.959 ± 1.367
5.178ProLeu: 5.178 ± 1.925
1.479ProMet: 1.479 ± 0.61
2.959ProAsn: 2.959 ± 1.346
1.479ProPro: 1.479 ± 0.61
3.698ProGln: 3.698 ± 1.296
3.698ProArg: 3.698 ± 1.283
3.698ProSer: 3.698 ± 3.034
2.959ProThr: 2.959 ± 2.144
4.438ProVal: 4.438 ± 1.095
0.0ProTrp: 0.0 ± 0.0
2.219ProTyr: 2.219 ± 1.935
0.0ProXaa: 0.0 ± 0.0
Gln
4.438GlnAla: 4.438 ± 1.402
0.0GlnCys: 0.0 ± 0.0
2.219GlnAsp: 2.219 ± 0.892
5.178GlnGlu: 5.178 ± 1.472
1.479GlnPhe: 1.479 ± 0.802
5.178GlnGly: 5.178 ± 1.587
0.0GlnHis: 0.0 ± 0.0
2.219GlnIle: 2.219 ± 1.298
4.438GlnLys: 4.438 ± 0.753
5.178GlnLeu: 5.178 ± 0.789
1.479GlnMet: 1.479 ± 1.365
3.698GlnAsn: 3.698 ± 1.717
4.438GlnPro: 4.438 ± 1.465
4.438GlnGln: 4.438 ± 1.431
2.219GlnArg: 2.219 ± 0.897
3.698GlnSer: 3.698 ± 1.308
6.657GlnThr: 6.657 ± 3.445
0.74GlnVal: 0.74 ± 0.682
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
9.615ArgAla: 9.615 ± 3.578
0.74ArgCys: 0.74 ± 0.658
4.438ArgAsp: 4.438 ± 0.753
2.959ArgGlu: 2.959 ± 0.685
1.479ArgPhe: 1.479 ± 0.673
3.698ArgGly: 3.698 ± 1.227
2.219ArgHis: 2.219 ± 0.897
5.178ArgIle: 5.178 ± 1.466
4.438ArgLys: 4.438 ± 1.554
8.136ArgLeu: 8.136 ± 3.095
0.0ArgMet: 0.0 ± 0.0
2.959ArgAsn: 2.959 ± 1.411
3.698ArgPro: 3.698 ± 1.476
4.438ArgGln: 4.438 ± 0.994
5.178ArgArg: 5.178 ± 1.876
3.698ArgSer: 3.698 ± 1.875
4.438ArgThr: 4.438 ± 2.509
0.74ArgVal: 0.74 ± 0.519
0.0ArgTrp: 0.0 ± 0.0
4.438ArgTyr: 4.438 ± 1.349
0.0ArgXaa: 0.0 ± 0.0
Ser
2.959SerAla: 2.959 ± 0.704
0.0SerCys: 0.0 ± 0.0
2.959SerAsp: 2.959 ± 0.988
6.657SerGlu: 6.657 ± 1.483
0.74SerPhe: 0.74 ± 0.519
3.698SerGly: 3.698 ± 1.696
0.74SerHis: 0.74 ± 0.519
4.438SerIle: 4.438 ± 1.846
2.959SerLys: 2.959 ± 2.632
8.136SerLeu: 8.136 ± 3.322
0.0SerMet: 0.0 ± 0.0
5.917SerAsn: 5.917 ± 1.408
5.917SerPro: 5.917 ± 2.457
2.959SerGln: 2.959 ± 1.901
5.178SerArg: 5.178 ± 1.065
3.698SerSer: 3.698 ± 1.11
4.438SerThr: 4.438 ± 1.901
5.178SerVal: 5.178 ± 1.077
0.0SerTrp: 0.0 ± 0.0
3.698SerTyr: 3.698 ± 1.308
0.0SerXaa: 0.0 ± 0.0
Thr
4.438ThrAla: 4.438 ± 2.504
0.74ThrCys: 0.74 ± 0.658
3.698ThrAsp: 3.698 ± 1.271
2.219ThrGlu: 2.219 ± 1.252
2.219ThrPhe: 2.219 ± 1.074
2.219ThrGly: 2.219 ± 1.158
0.74ThrHis: 0.74 ± 0.519
1.479ThrIle: 1.479 ± 1.057
2.959ThrLys: 2.959 ± 1.367
5.917ThrLeu: 5.917 ± 3.253
0.0ThrMet: 0.0 ± 0.772
3.698ThrAsn: 3.698 ± 2.546
5.178ThrPro: 5.178 ± 1.443
2.959ThrGln: 2.959 ± 1.682
3.698ThrArg: 3.698 ± 1.262
5.178ThrSer: 5.178 ± 2.912
3.698ThrThr: 3.698 ± 2.132
2.959ThrVal: 2.959 ± 1.284
0.0ThrTrp: 0.0 ± 0.0
2.219ThrTyr: 2.219 ± 1.668
0.0ThrXaa: 0.0 ± 0.0
Val
2.959ValAla: 2.959 ± 1.43
0.0ValCys: 0.0 ± 0.0
2.959ValAsp: 2.959 ± 1.43
2.219ValGlu: 2.219 ± 1.335
2.959ValPhe: 2.959 ± 1.43
3.698ValGly: 3.698 ± 1.308
2.219ValHis: 2.219 ± 0.923
0.74ValIle: 0.74 ± 0.519
1.479ValLys: 1.479 ± 0.61
3.698ValLeu: 3.698 ± 1.258
1.479ValMet: 1.479 ± 1.039
2.219ValAsn: 2.219 ± 0.99
4.438ValPro: 4.438 ± 2.05
0.74ValGln: 0.74 ± 0.956
0.74ValArg: 0.74 ± 0.519
4.438ValSer: 4.438 ± 1.235
1.479ValThr: 1.479 ± 1.316
1.479ValVal: 1.479 ± 1.039
0.74ValTrp: 0.74 ± 0.519
2.219ValTyr: 2.219 ± 0.892
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.479TrpGlu: 1.479 ± 0.673
0.0TrpPhe: 0.0 ± 0.0
0.74TrpGly: 0.74 ± 0.519
1.479TrpHis: 1.479 ± 0.673
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.74TrpLeu: 0.74 ± 0.519
0.0TrpMet: 0.0 ± 0.0
0.74TrpAsn: 0.74 ± 1.162
1.479TrpPro: 1.479 ± 1.039
0.74TrpGln: 0.74 ± 0.658
0.74TrpArg: 0.74 ± 1.162
0.74TrpSer: 0.74 ± 0.519
0.74TrpThr: 0.74 ± 0.658
0.0TrpVal: 0.0 ± 0.0
0.74TrpTrp: 0.74 ± 0.682
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.479TyrAla: 1.479 ± 0.61
0.0TyrCys: 0.0 ± 0.0
2.959TyrAsp: 2.959 ± 1.554
2.959TyrGlu: 2.959 ± 1.621
1.479TyrPhe: 1.479 ± 0.61
2.219TyrGly: 2.219 ± 1.059
2.959TyrHis: 2.959 ± 1.782
2.219TyrIle: 2.219 ± 1.558
0.0TyrLys: 0.0 ± 0.0
5.178TyrLeu: 5.178 ± 1.484
2.219TyrMet: 2.219 ± 0.931
3.698TyrAsn: 3.698 ± 1.616
0.0TyrPro: 0.0 ± 0.0
2.219TyrGln: 2.219 ± 1.558
4.438TyrArg: 4.438 ± 0.886
2.959TyrSer: 2.959 ± 2.215
2.219TyrThr: 2.219 ± 1.158
0.74TyrVal: 0.74 ± 0.658
0.74TyrTrp: 0.74 ± 0.519
3.698TyrTyr: 3.698 ± 1.476
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1353 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski