Amino acid dipepetide frequency for Balearica regulorum gibbericeps (East African grey crowned-crane)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.579AlaAla: 5.579 ± 0.058	1.305AlaCys: 1.305 ± 0.022	2.991AlaAsp: 2.991 ± 0.033	4.561AlaGlu: 4.561 ± 0.038	2.601AlaPhe: 2.601 ± 0.031	3.813AlaGly: 3.813 ± 0.039	1.325AlaHis: 1.325 ± 0.02	3.149AlaIle: 3.149 ± 0.034	3.727AlaLys: 3.727 ± 0.035	6.327AlaLeu: 6.327 ± 0.051	1.518AlaMet: 1.518 ± 0.022	2.281AlaAsn: 2.281 ± 0.024	2.79AlaPro: 2.79 ± 0.034	2.739AlaGln: 2.739 ± 0.029	2.9AlaArg: 2.9 ± 0.033	5.175AlaSer: 5.175 ± 0.046	3.334AlaThr: 3.334 ± 0.031	4.884AlaVal: 4.884 ± 0.036	0.696AlaTrp: 0.696 ± 0.013	1.649AlaTyr: 1.649 ± 0.023	0.002AlaXaa: 0.002 ± 0.001
Cys	1.169CysAla: 1.169 ± 0.022	0.663CysCys: 0.663 ± 0.018	1.08CysAsp: 1.08 ± 0.024	1.341CysGlu: 1.341 ± 0.027	0.926CysPhe: 0.926 ± 0.016	1.435CysGly: 1.435 ± 0.029	0.65CysHis: 0.65 ± 0.016	1.194CysIle: 1.194 ± 0.023	1.386CysLys: 1.386 ± 0.023	2.167CysLeu: 2.167 ± 0.033	0.467CysMet: 0.467 ± 0.01	0.941CysAsn: 0.941 ± 0.019	1.2CysPro: 1.2 ± 0.028	1.077CysGln: 1.077 ± 0.02	1.211CysArg: 1.211 ± 0.022	2.012CysSer: 2.012 ± 0.027	1.233CysThr: 1.233 ± 0.025	1.352CysVal: 1.352 ± 0.025	0.294CysTrp: 0.294 ± 0.009	0.696CysTyr: 0.696 ± 0.016	0.001CysXaa: 0.001 ± 0.0
Asp	2.892AspAla: 2.892 ± 0.028	1.114AspCys: 1.114 ± 0.021	2.915AspAsp: 2.915 ± 0.035	3.716AspGlu: 3.716 ± 0.039	2.291AspPhe: 2.291 ± 0.025	3.262AspGly: 3.262 ± 0.037	1.171AspHis: 1.171 ± 0.019	2.977AspIle: 2.977 ± 0.032	2.863AspLys: 2.863 ± 0.033	5.062AspLeu: 5.062 ± 0.043	1.175AspMet: 1.175 ± 0.02	2.029AspAsn: 2.029 ± 0.026	2.63AspPro: 2.63 ± 0.028	1.876AspGln: 1.876 ± 0.024	2.4AspArg: 2.4 ± 0.031	4.158AspSer: 4.158 ± 0.042	2.526AspThr: 2.526 ± 0.027	3.229AspVal: 3.229 ± 0.034	0.656AspTrp: 0.656 ± 0.016	1.678AspTyr: 1.678 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	4.629GluAla: 4.629 ± 0.046	1.34GluCys: 1.34 ± 0.037	4.544GluAsp: 4.544 ± 0.041	7.905GluGlu: 7.905 ± 0.082	2.252GluPhe: 2.252 ± 0.025	3.825GluGly: 3.825 ± 0.04	1.538GluHis: 1.538 ± 0.02	3.61GluIle: 3.61 ± 0.034	5.852GluLys: 5.852 ± 0.066	6.34GluLeu: 6.34 ± 0.055	1.818GluMet: 1.818 ± 0.028	3.58GluAsn: 3.58 ± 0.033	2.541GluPro: 2.541 ± 0.028	3.252GluGln: 3.252 ± 0.036	3.923GluArg: 3.923 ± 0.053	4.508GluSer: 4.508 ± 0.04	3.613GluThr: 3.613 ± 0.035	4.313GluVal: 4.313 ± 0.035	0.716GluTrp: 0.716 ± 0.015	1.856GluTyr: 1.856 ± 0.023	0.001GluXaa: 0.001 ± 0.001
Phe	2.167PheAla: 2.167 ± 0.025	1.036PheCys: 1.036 ± 0.018	1.855PheAsp: 1.855 ± 0.023	2.182PheGlu: 2.182 ± 0.028	1.851PhePhe: 1.851 ± 0.029	2.343PheGly: 2.343 ± 0.03	1.091PheHis: 1.091 ± 0.018	2.167PheIle: 2.167 ± 0.028	2.084PheLys: 2.084 ± 0.025	4.257PheLeu: 4.257 ± 0.042	0.812PheMet: 0.812 ± 0.013	1.569PheAsn: 1.569 ± 0.022	1.952PhePro: 1.952 ± 0.03	1.81PheGln: 1.81 ± 0.025	1.875PheArg: 1.875 ± 0.024	3.536PheSer: 3.536 ± 0.031	2.229PheThr: 2.229 ± 0.026	2.397PheVal: 2.397 ± 0.032	0.54PheTrp: 0.54 ± 0.012	1.373PheTyr: 1.373 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	3.397GlyAla: 3.397 ± 0.036	1.23GlyCys: 1.23 ± 0.02	2.942GlyAsp: 2.942 ± 0.038	3.734GlyGlu: 3.734 ± 0.052	2.504GlyPhe: 2.504 ± 0.034	3.787GlyGly: 3.787 ± 0.061	1.491GlyHis: 1.491 ± 0.02	3.15GlyIle: 3.15 ± 0.036	4.01GlyLys: 4.01 ± 0.039	5.118GlyLeu: 5.118 ± 0.057	1.37GlyMet: 1.37 ± 0.021	2.644GlyAsn: 2.644 ± 0.029	2.711GlyPro: 2.711 ± 0.086	2.524GlyGln: 2.524 ± 0.036	3.035GlyArg: 3.035 ± 0.038	4.952GlySer: 4.952 ± 0.051	3.4GlyThr: 3.4 ± 0.037	3.414GlyVal: 3.414 ± 0.036	0.742GlyTrp: 0.742 ± 0.017	1.888GlyTyr: 1.888 ± 0.026	0.001GlyXaa: 0.001 ± 0.001
His	1.328HisAla: 1.328 ± 0.02	0.724HisCys: 0.724 ± 0.015	0.929HisAsp: 0.929 ± 0.016	1.374HisGlu: 1.374 ± 0.018	1.091HisPhe: 1.091 ± 0.017	1.446HisGly: 1.446 ± 0.021	0.863HisHis: 0.863 ± 0.019	1.342HisIle: 1.342 ± 0.016	1.413HisLys: 1.413 ± 0.02	2.806HisLeu: 2.806 ± 0.03	0.587HisMet: 0.587 ± 0.014	1.007HisAsn: 1.007 ± 0.018	1.46HisPro: 1.46 ± 0.025	1.181HisGln: 1.181 ± 0.02	1.414HisArg: 1.414 ± 0.019	2.194HisSer: 2.194 ± 0.025	1.306HisThr: 1.306 ± 0.02	1.528HisVal: 1.528 ± 0.02	0.343HisTrp: 0.343 ± 0.011	0.884HisTyr: 0.884 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	3.091IleAla: 3.091 ± 0.031	1.275IleCys: 1.275 ± 0.023	2.399IleAsp: 2.399 ± 0.029	2.957IleGlu: 2.957 ± 0.034	2.253IlePhe: 2.253 ± 0.029	2.565IleGly: 2.565 ± 0.029	1.415IleHis: 1.415 ± 0.019	2.856IleIle: 2.856 ± 0.032	3.115IleLys: 3.115 ± 0.035	5.042IleLeu: 5.042 ± 0.052	1.098IleMet: 1.098 ± 0.017	2.264IleAsn: 2.264 ± 0.023	2.89IlePro: 2.89 ± 0.028	2.486IleGln: 2.486 ± 0.028	2.52IleArg: 2.52 ± 0.029	4.195IleSer: 4.195 ± 0.035	2.933IleThr: 2.933 ± 0.031	2.997IleVal: 2.997 ± 0.029	0.604IleTrp: 0.604 ± 0.013	1.655IleTyr: 1.655 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.115LysAla: 4.115 ± 0.043	1.265LysCys: 1.265 ± 0.02	3.573LysAsp: 3.573 ± 0.036	5.838LysGlu: 5.838 ± 0.061	1.966LysPhe: 1.966 ± 0.025	3.486LysGly: 3.486 ± 0.055	1.612LysHis: 1.612 ± 0.027	3.253LysIle: 3.253 ± 0.036	5.508LysLys: 5.508 ± 0.07	5.778LysLeu: 5.778 ± 0.057	1.601LysMet: 1.601 ± 0.022	2.865LysAsn: 2.865 ± 0.033	3.104LysPro: 3.104 ± 0.039	3.079LysGln: 3.079 ± 0.039	3.58LysArg: 3.58 ± 0.037	4.38LysSer: 4.38 ± 0.042	3.495LysThr: 3.495 ± 0.032	3.774LysVal: 3.774 ± 0.035	0.682LysTrp: 0.682 ± 0.013	1.945LysTyr: 1.945 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	6.166LeuAla: 6.166 ± 0.05	2.204LeuCys: 2.204 ± 0.031	4.788LeuAsp: 4.788 ± 0.036	6.981LeuGlu: 6.981 ± 0.067	3.627LeuPhe: 3.627 ± 0.041	5.11LeuGly: 5.11 ± 0.04	2.655LeuHis: 2.655 ± 0.033	4.346LeuIle: 4.346 ± 0.041	6.485LeuLys: 6.485 ± 0.053	10.083LeuLeu: 10.083 ± 0.091	2.065LeuMet: 2.065 ± 0.026	3.947LeuAsn: 3.947 ± 0.039	5.311LeuPro: 5.311 ± 0.054	5.691LeuGln: 5.691 ± 0.052	5.072LeuArg: 5.072 ± 0.047	7.839LeuSer: 7.839 ± 0.063	5.062LeuThr: 5.062 ± 0.045	5.474LeuVal: 5.474 ± 0.048	1.085LeuTrp: 1.085 ± 0.017	2.804LeuTyr: 2.804 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	1.658MetAla: 1.658 ± 0.023	0.429MetCys: 0.429 ± 0.013	1.301MetAsp: 1.301 ± 0.018	1.907MetGlu: 1.907 ± 0.027	0.867MetPhe: 0.867 ± 0.014	1.248MetGly: 1.248 ± 0.021	0.537MetHis: 0.537 ± 0.013	1.015MetIle: 1.015 ± 0.015	1.623MetLys: 1.623 ± 0.024	2.089MetLeu: 2.089 ± 0.026	0.62MetMet: 0.62 ± 0.016	1.035MetAsn: 1.035 ± 0.017	1.04MetPro: 1.04 ± 0.021	1.066MetGln: 1.066 ± 0.02	1.056MetArg: 1.056 ± 0.018	1.574MetSer: 1.574 ± 0.022	1.194MetThr: 1.194 ± 0.018	1.443MetVal: 1.443 ± 0.021	0.261MetTrp: 0.261 ± 0.008	0.678MetTyr: 0.678 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.363AsnAla: 2.363 ± 0.027	1.021AsnCys: 1.021 ± 0.021	1.767AsnAsp: 1.767 ± 0.022	2.67AsnGlu: 2.67 ± 0.028	1.686AsnPhe: 1.686 ± 0.02	2.799AsnGly: 2.799 ± 0.035	1.023AsnHis: 1.023 ± 0.017	2.594AsnIle: 2.594 ± 0.032	2.688AsnLys: 2.688 ± 0.03	4.159AsnLeu: 4.159 ± 0.04	1.03AsnMet: 1.03 ± 0.02	1.937AsnAsn: 1.937 ± 0.028	2.349AsnPro: 2.349 ± 0.033	1.761AsnGln: 1.761 ± 0.025	2.033AsnArg: 2.033 ± 0.026	3.544AsnSer: 3.544 ± 0.036	2.336AsnThr: 2.336 ± 0.031	2.574AsnVal: 2.574 ± 0.026	0.507AsnTrp: 0.507 ± 0.011	1.344AsnTyr: 1.344 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	3.605ProAla: 3.605 ± 0.041	1.026ProCys: 1.026 ± 0.023	2.632ProAsp: 2.632 ± 0.026	3.806ProGlu: 3.806 ± 0.038	1.916ProPhe: 1.916 ± 0.025	3.665ProGly: 3.665 ± 0.127	1.23ProHis: 1.23 ± 0.02	2.005ProIle: 2.005 ± 0.028	2.779ProLys: 2.779 ± 0.035	4.602ProLeu: 4.602 ± 0.037	0.963ProMet: 0.963 ± 0.018	1.929ProAsn: 1.929 ± 0.025	4.152ProPro: 4.152 ± 0.082	2.314ProGln: 2.314 ± 0.037	2.427ProArg: 2.427 ± 0.027	4.818ProSer: 4.818 ± 0.052	2.669ProThr: 2.669 ± 0.034	3.726ProVal: 3.726 ± 0.045	0.546ProTrp: 0.546 ± 0.013	1.456ProTyr: 1.456 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.002GlnAla: 3.002 ± 0.03	0.98GlnCys: 0.98 ± 0.02	2.241GlnAsp: 2.241 ± 0.024	3.75GlnGlu: 3.75 ± 0.043	1.459GlnPhe: 1.459 ± 0.022	2.452GlnGly: 2.452 ± 0.038	1.292GlnHis: 1.292 ± 0.021	2.292GlnIle: 2.292 ± 0.027	3.27GlnLys: 3.27 ± 0.035	4.631GlnLeu: 4.631 ± 0.047	1.133GlnMet: 1.133 ± 0.018	2.091GlnAsn: 2.091 ± 0.024	2.364GlnPro: 2.364 ± 0.039	3.106GlnGln: 3.106 ± 0.067	2.639GlnArg: 2.639 ± 0.033	3.237GlnSer: 3.237 ± 0.038	2.426GlnThr: 2.426 ± 0.032	2.782GlnVal: 2.782 ± 0.03	0.516GlnTrp: 0.516 ± 0.013	1.322GlnTyr: 1.322 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	2.965ArgAla: 2.965 ± 0.031	1.119ArgCys: 1.119 ± 0.028	2.59ArgAsp: 2.59 ± 0.034	3.65ArgGlu: 3.65 ± 0.045	1.869ArgPhe: 1.869 ± 0.022	2.776ArgGly: 2.776 ± 0.041	1.415ArgHis: 1.415 ± 0.019	2.641ArgIle: 2.641 ± 0.026	3.95ArgLys: 3.95 ± 0.045	4.713ArgLeu: 4.713 ± 0.045	1.18ArgMet: 1.18 ± 0.016	2.312ArgAsn: 2.312 ± 0.025	2.38ArgPro: 2.38 ± 0.031	2.477ArgGln: 2.477 ± 0.033	3.586ArgArg: 3.586 ± 0.037	3.942ArgSer: 3.942 ± 0.046	2.715ArgThr: 2.715 ± 0.028	2.862ArgVal: 2.862 ± 0.031	0.604ArgTrp: 0.604 ± 0.013	1.605ArgTyr: 1.605 ± 0.02	0.002ArgXaa: 0.002 ± 0.001
Ser	5.053SerAla: 5.053 ± 0.048	1.85SerCys: 1.85 ± 0.027	4.039SerAsp: 4.039 ± 0.042	5.179SerGlu: 5.179 ± 0.043	3.191SerPhe: 3.191 ± 0.031	4.889SerGly: 4.889 ± 0.042	2.04SerHis: 2.04 ± 0.025	3.674SerIle: 3.674 ± 0.033	4.624SerLys: 4.624 ± 0.047	7.964SerLeu: 7.964 ± 0.058	1.645SerMet: 1.645 ± 0.02	3.174SerAsn: 3.174 ± 0.034	5.071SerPro: 5.071 ± 0.066	3.697SerGln: 3.697 ± 0.037	4.04SerArg: 4.04 ± 0.044	9.161SerSer: 9.161 ± 0.11	4.638SerThr: 4.638 ± 0.046	5.138SerVal: 5.138 ± 0.044	0.964SerTrp: 0.964 ± 0.017	2.308SerTyr: 2.308 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	3.829ThrAla: 3.829 ± 0.033	1.346ThrCys: 1.346 ± 0.028	2.763ThrAsp: 2.763 ± 0.032	3.814ThrGlu: 3.814 ± 0.037	2.205ThrPhe: 2.205 ± 0.028	3.409ThrGly: 3.409 ± 0.034	1.184ThrHis: 1.184 ± 0.017	2.654ThrIle: 2.654 ± 0.028	2.979ThrLys: 2.979 ± 0.031	5.214ThrLeu: 5.214 ± 0.039	1.142ThrMet: 1.142 ± 0.016	1.998ThrAsn: 1.998 ± 0.023	3.129ThrPro: 3.129 ± 0.037	2.162ThrGln: 2.162 ± 0.025	2.322ThrArg: 2.322 ± 0.023	4.75ThrSer: 4.75 ± 0.053	3.09ThrThr: 3.09 ± 0.039	4.165ThrVal: 4.165 ± 0.038	0.671ThrTrp: 0.671 ± 0.014	1.62ThrTyr: 1.62 ± 0.025	0.001ThrXaa: 0.001 ± 0.0
Val	4.038ValAla: 4.038 ± 0.036	1.538ValCys: 1.538 ± 0.022	3.093ValAsp: 3.093 ± 0.036	3.951ValGlu: 3.951 ± 0.035	2.667ValPhe: 2.667 ± 0.034	3.302ValGly: 3.302 ± 0.034	1.598ValHis: 1.598 ± 0.021	3.353ValIle: 3.353 ± 0.032	3.885ValLys: 3.885 ± 0.036	6.274ValLeu: 6.274 ± 0.045	1.4ValMet: 1.4 ± 0.018	2.625ValAsn: 2.625 ± 0.029	3.42ValPro: 3.42 ± 0.038	2.816ValGln: 2.816 ± 0.029	2.962ValArg: 2.962 ± 0.032	5.04ValSer: 5.04 ± 0.04	3.931ValThr: 3.931 ± 0.037	4.21ValVal: 4.21 ± 0.044	0.716ValTrp: 0.716 ± 0.016	1.892ValTyr: 1.892 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.655TrpAla: 0.655 ± 0.013	0.243TrpCys: 0.243 ± 0.008	0.664TrpAsp: 0.664 ± 0.017	0.782TrpGlu: 0.782 ± 0.016	0.476TrpPhe: 0.476 ± 0.011	0.618TrpGly: 0.618 ± 0.017	0.291TrpHis: 0.291 ± 0.009	0.631TrpIle: 0.631 ± 0.013	0.91TrpLys: 0.91 ± 0.018	1.176TrpLeu: 1.176 ± 0.018	0.322TrpMet: 0.322 ± 0.009	0.61TrpAsn: 0.61 ± 0.015	0.421TrpPro: 0.421 ± 0.011	0.535TrpGln: 0.535 ± 0.014	0.633TrpArg: 0.633 ± 0.013	0.889TrpSer: 0.889 ± 0.019	0.663TrpThr: 0.663 ± 0.013	0.656TrpVal: 0.656 ± 0.012	0.189TrpTrp: 0.189 ± 0.008	0.377TrpTyr: 0.377 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.646TyrAla: 1.646 ± 0.02	0.784TyrCys: 0.784 ± 0.015	1.512TyrAsp: 1.512 ± 0.021	1.859TyrGlu: 1.859 ± 0.024	1.427TyrPhe: 1.427 ± 0.021	1.813TyrGly: 1.813 ± 0.03	0.799TyrHis: 0.799 ± 0.015	1.707TyrIle: 1.707 ± 0.022	1.749TyrLys: 1.749 ± 0.022	2.995TyrLeu: 2.995 ± 0.032	0.698TyrMet: 0.698 ± 0.013	1.346TyrAsn: 1.346 ± 0.023	1.351TyrPro: 1.351 ± 0.02	1.336TyrGln: 1.336 ± 0.019	1.725TyrArg: 1.725 ± 0.024	2.431TyrSer: 2.431 ± 0.028	1.653TyrThr: 1.653 ± 0.023	1.792TyrVal: 1.792 ± 0.025	0.408TyrTrp: 0.408 ± 0.013	1.143TyrTyr: 1.143 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.031XaaXaa: 0.031 ± 0.008

Statistics based on 8821 proteins (3859431 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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