Amino acid dipepetide frequency for [Candida] haemuloni

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.701AlaAla: 5.701 ± 0.073	0.719AlaCys: 0.719 ± 0.017	3.438AlaAsp: 3.438 ± 0.037	4.356AlaGlu: 4.356 ± 0.054	2.856AlaPhe: 2.856 ± 0.035	3.833AlaGly: 3.833 ± 0.055	1.343AlaHis: 1.343 ± 0.022	3.757AlaIle: 3.757 ± 0.043	4.541AlaLys: 4.541 ± 0.052	6.29AlaLeu: 6.29 ± 0.058	1.396AlaMet: 1.396 ± 0.025	3.057AlaAsn: 3.057 ± 0.04	3.523AlaPro: 3.523 ± 0.062	2.648AlaGln: 2.648 ± 0.036	3.024AlaArg: 3.024 ± 0.035	6.615AlaSer: 6.615 ± 0.061	3.858AlaThr: 3.858 ± 0.038	4.206AlaVal: 4.206 ± 0.048	0.618AlaTrp: 0.618 ± 0.015	1.969AlaTyr: 1.969 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	0.62CysAla: 0.62 ± 0.015	0.211CysCys: 0.211 ± 0.009	0.612CysAsp: 0.612 ± 0.016	0.583CysGlu: 0.583 ± 0.016	0.613CysPhe: 0.613 ± 0.016	0.767CysGly: 0.767 ± 0.019	0.29CysHis: 0.29 ± 0.013	0.694CysIle: 0.694 ± 0.015	0.605CysLys: 0.605 ± 0.013	1.159CysLeu: 1.159 ± 0.021	0.22CysMet: 0.22 ± 0.008	0.451CysAsn: 0.451 ± 0.014	0.486CysPro: 0.486 ± 0.015	0.361CysGln: 0.361 ± 0.013	0.44CysArg: 0.44 ± 0.014	0.857CysSer: 0.857 ± 0.021	0.514CysThr: 0.514 ± 0.014	0.753CysVal: 0.753 ± 0.017	0.139CysTrp: 0.139 ± 0.007	0.412CysTyr: 0.412 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	3.854AspAla: 3.854 ± 0.045	0.573AspCys: 0.573 ± 0.016	4.824AspAsp: 4.824 ± 0.067	5.348AspGlu: 5.348 ± 0.059	2.877AspPhe: 2.877 ± 0.036	3.302AspGly: 3.302 ± 0.071	1.244AspHis: 1.244 ± 0.021	3.564AspIle: 3.564 ± 0.036	3.591AspLys: 3.591 ± 0.042	5.692AspLeu: 5.692 ± 0.045	1.162AspMet: 1.162 ± 0.019	2.568AspAsn: 2.568 ± 0.033	2.772AspPro: 2.772 ± 0.034	1.958AspGln: 1.958 ± 0.03	2.236AspArg: 2.236 ± 0.031	5.212AspSer: 5.212 ± 0.067	2.915AspThr: 2.915 ± 0.032	3.893AspVal: 3.893 ± 0.04	0.642AspTrp: 0.642 ± 0.018	2.146AspTyr: 2.146 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	4.709GluAla: 4.709 ± 0.052	0.562GluCys: 0.562 ± 0.015	4.782GluAsp: 4.782 ± 0.051	7.027GluGlu: 7.027 ± 0.099	2.652GluPhe: 2.652 ± 0.039	3.245GluGly: 3.245 ± 0.046	1.373GluHis: 1.373 ± 0.022	3.613GluIle: 3.613 ± 0.042	5.44GluLys: 5.44 ± 0.065	6.224GluLeu: 6.224 ± 0.055	1.29GluMet: 1.29 ± 0.023	3.399GluAsn: 3.399 ± 0.036	2.813GluPro: 2.813 ± 0.046	2.704GluGln: 2.704 ± 0.035	3.091GluArg: 3.091 ± 0.04	5.604GluSer: 5.604 ± 0.064	3.738GluThr: 3.738 ± 0.048	4.13GluVal: 4.13 ± 0.043	0.681GluTrp: 0.681 ± 0.017	2.093GluTyr: 2.093 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	2.825PheAla: 2.825 ± 0.031	0.542PheCys: 0.542 ± 0.014	2.925PheAsp: 2.925 ± 0.033	2.789PheGlu: 2.789 ± 0.033	2.155PhePhe: 2.155 ± 0.035	2.963PheGly: 2.963 ± 0.054	1.022PheHis: 1.022 ± 0.02	2.434PheIle: 2.434 ± 0.037	2.715PheLys: 2.715 ± 0.032	3.97PheLeu: 3.97 ± 0.048	0.941PheMet: 0.941 ± 0.018	2.287PheAsn: 2.287 ± 0.031	1.852PhePro: 1.852 ± 0.039	1.638PheGln: 1.638 ± 0.027	1.811PheArg: 1.811 ± 0.026	3.722PheSer: 3.722 ± 0.04	2.468PheThr: 2.468 ± 0.053	2.957PheVal: 2.957 ± 0.034	0.56PheTrp: 0.56 ± 0.017	1.517PheTyr: 1.517 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	3.893GlyAla: 3.893 ± 0.062	0.691GlyCys: 0.691 ± 0.019	3.216GlyAsp: 3.216 ± 0.042	3.353GlyGlu: 3.353 ± 0.044	2.754GlyPhe: 2.754 ± 0.036	3.952GlyGly: 3.952 ± 0.068	1.295GlyHis: 1.295 ± 0.024	3.173GlyIle: 3.173 ± 0.039	3.621GlyLys: 3.621 ± 0.044	4.951GlyLeu: 4.951 ± 0.052	1.126GlyMet: 1.126 ± 0.018	2.714GlyAsn: 2.714 ± 0.047	2.318GlyPro: 2.318 ± 0.048	2.013GlyGln: 2.013 ± 0.037	2.462GlyArg: 2.462 ± 0.039	5.756GlySer: 5.756 ± 0.102	3.058GlyThr: 3.058 ± 0.05	3.659GlyVal: 3.659 ± 0.057	0.67GlyTrp: 0.67 ± 0.017	1.975GlyTyr: 1.975 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	1.232HisAla: 1.232 ± 0.021	0.288HisCys: 0.288 ± 0.01	1.298HisAsp: 1.298 ± 0.023	1.457HisGlu: 1.457 ± 0.025	1.041HisPhe: 1.041 ± 0.021	1.329HisGly: 1.329 ± 0.025	0.771HisHis: 0.771 ± 0.024	1.257HisIle: 1.257 ± 0.023	1.352HisLys: 1.352 ± 0.021	2.163HisLeu: 2.163 ± 0.032	0.445HisMet: 0.445 ± 0.014	1.031HisAsn: 1.031 ± 0.022	1.207HisPro: 1.207 ± 0.022	0.989HisGln: 0.989 ± 0.026	1.075HisArg: 1.075 ± 0.021	1.947HisSer: 1.947 ± 0.031	1.069HisThr: 1.069 ± 0.02	1.284HisVal: 1.284 ± 0.024	0.245HisTrp: 0.245 ± 0.011	0.787HisTyr: 0.787 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	3.621IleAla: 3.621 ± 0.034	0.684IleCys: 0.684 ± 0.018	3.58IleAsp: 3.58 ± 0.037	3.498IleGlu: 3.498 ± 0.041	2.433IlePhe: 2.433 ± 0.036	2.997IleGly: 2.997 ± 0.04	1.237IleHis: 1.237 ± 0.022	2.983IleIle: 2.983 ± 0.043	3.461IleLys: 3.461 ± 0.04	4.913IleLeu: 4.913 ± 0.055	1.094IleMet: 1.094 ± 0.019	2.704IleAsn: 2.704 ± 0.034	2.811IlePro: 2.811 ± 0.036	1.939IleGln: 1.939 ± 0.03	2.433IleArg: 2.433 ± 0.029	4.587IleSer: 4.587 ± 0.048	3.052IleThr: 3.052 ± 0.037	3.607IleVal: 3.607 ± 0.053	0.606IleTrp: 0.606 ± 0.015	1.736IleTyr: 1.736 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.694LysAla: 4.694 ± 0.056	0.639LysCys: 0.639 ± 0.016	4.03LysAsp: 4.03 ± 0.043	5.171LysGlu: 5.171 ± 0.065	2.686LysPhe: 2.686 ± 0.036	3.103LysGly: 3.103 ± 0.035	1.571LysHis: 1.571 ± 0.023	3.46LysIle: 3.46 ± 0.038	6.048LysLys: 6.048 ± 0.082	6.369LysLeu: 6.369 ± 0.061	1.29LysMet: 1.29 ± 0.025	3.238LysAsn: 3.238 ± 0.038	3.244LysPro: 3.244 ± 0.042	2.791LysGln: 2.791 ± 0.036	3.63LysArg: 3.63 ± 0.042	5.402LysSer: 5.402 ± 0.056	3.639LysThr: 3.639 ± 0.047	4.08LysVal: 4.08 ± 0.047	0.714LysTrp: 0.714 ± 0.016	2.327LysTyr: 2.327 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	6.365LeuAla: 6.365 ± 0.054	1.125LeuCys: 1.125 ± 0.021	5.411LeuAsp: 5.411 ± 0.052	5.828LeuGlu: 5.828 ± 0.059	3.833LeuPhe: 3.833 ± 0.048	5.022LeuGly: 5.022 ± 0.049	2.095LeuHis: 2.095 ± 0.031	4.792LeuIle: 4.792 ± 0.056	6.189LeuLys: 6.189 ± 0.054	8.502LeuLeu: 8.502 ± 0.072	1.804LeuMet: 1.804 ± 0.026	4.493LeuAsn: 4.493 ± 0.05	4.562LeuPro: 4.562 ± 0.047	3.884LeuGln: 3.884 ± 0.036	4.737LeuArg: 4.737 ± 0.049	8.234LeuSer: 8.234 ± 0.062	4.933LeuThr: 4.933 ± 0.047	5.756LeuVal: 5.756 ± 0.054	0.909LeuTrp: 0.909 ± 0.017	2.787LeuTyr: 2.787 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	1.601MetAla: 1.601 ± 0.025	0.236MetCys: 0.236 ± 0.008	1.186MetAsp: 1.186 ± 0.019	1.213MetGlu: 1.213 ± 0.023	0.892MetPhe: 0.892 ± 0.028	1.205MetGly: 1.205 ± 0.024	0.344MetHis: 0.344 ± 0.01	0.999MetIle: 0.999 ± 0.021	1.366MetLys: 1.366 ± 0.024	1.706MetLeu: 1.706 ± 0.029	0.453MetMet: 0.453 ± 0.015	1.043MetAsn: 1.043 ± 0.021	0.975MetPro: 0.975 ± 0.022	0.585MetGln: 0.585 ± 0.016	0.853MetArg: 0.853 ± 0.02	2.09MetSer: 2.09 ± 0.026	1.05MetThr: 1.05 ± 0.021	1.281MetVal: 1.281 ± 0.022	0.182MetTrp: 0.182 ± 0.009	0.584MetTyr: 0.584 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.097AsnAla: 3.097 ± 0.04	0.503AsnCys: 0.503 ± 0.016	3.046AsnAsp: 3.046 ± 0.036	3.242AsnGlu: 3.242 ± 0.041	2.161AsnPhe: 2.161 ± 0.027	3.163AsnGly: 3.163 ± 0.064	1.07AsnHis: 1.07 ± 0.022	2.64AsnIle: 2.64 ± 0.034	2.932AsnLys: 2.932 ± 0.04	4.324AsnLeu: 4.324 ± 0.044	0.998AsnMet: 0.998 ± 0.021	2.482AsnAsn: 2.482 ± 0.043	2.39AsnPro: 2.39 ± 0.038	1.834AsnGln: 1.834 ± 0.035	1.951AsnArg: 1.951 ± 0.028	4.028AsnSer: 4.028 ± 0.049	2.523AsnThr: 2.523 ± 0.031	3.036AsnVal: 3.036 ± 0.037	0.555AsnTrp: 0.555 ± 0.015	1.801AsnTyr: 1.801 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	3.331ProAla: 3.331 ± 0.053	0.365ProCys: 0.365 ± 0.01	2.532ProAsp: 2.532 ± 0.027	3.888ProGlu: 3.888 ± 0.043	1.958ProPhe: 1.958 ± 0.028	2.628ProGly: 2.628 ± 0.041	1.117ProHis: 1.117 ± 0.029	2.337ProIle: 2.337 ± 0.033	3.385ProLys: 3.385 ± 0.052	3.872ProLeu: 3.872 ± 0.041	0.832ProMet: 0.832 ± 0.018	2.15ProAsn: 2.15 ± 0.033	3.262ProPro: 3.262 ± 0.089	2.537ProGln: 2.537 ± 0.048	2.081ProArg: 2.081 ± 0.033	4.998ProSer: 4.998 ± 0.065	2.92ProThr: 2.92 ± 0.049	3.256ProVal: 3.256 ± 0.047	0.48ProTrp: 0.48 ± 0.015	1.464ProTyr: 1.464 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	2.655GlnAla: 2.655 ± 0.039	0.365GlnCys: 0.365 ± 0.011	1.966GlnAsp: 1.966 ± 0.029	2.716GlnGlu: 2.716 ± 0.036	1.664GlnPhe: 1.664 ± 0.031	2.052GlnGly: 2.052 ± 0.033	1.031GlnHis: 1.031 ± 0.024	1.995GlnIle: 1.995 ± 0.027	2.742GlnLys: 2.742 ± 0.033	3.703GlnLeu: 3.703 ± 0.042	0.879GlnMet: 0.879 ± 0.023	1.931GlnAsn: 1.931 ± 0.034	2.099GlnPro: 2.099 ± 0.046	2.775GlnGln: 2.775 ± 0.095	2.028GlnArg: 2.028 ± 0.03	3.171GlnSer: 3.171 ± 0.039	2.012GlnThr: 2.012 ± 0.038	2.205GlnVal: 2.205 ± 0.027	0.424GlnTrp: 0.424 ± 0.015	1.28GlnTyr: 1.28 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	2.943ArgAla: 2.943 ± 0.033	0.495ArgCys: 0.495 ± 0.013	2.533ArgAsp: 2.533 ± 0.037	2.901ArgGlu: 2.901 ± 0.038	2.117ArgPhe: 2.117 ± 0.029	2.302ArgGly: 2.302 ± 0.037	1.062ArgHis: 1.062 ± 0.023	2.471ArgIle: 2.471 ± 0.034	3.537ArgLys: 3.537 ± 0.034	4.39ArgLeu: 4.39 ± 0.043	0.953ArgMet: 0.953 ± 0.02	2.204ArgAsn: 2.204 ± 0.031	2.006ArgPro: 2.006 ± 0.032	1.923ArgGln: 1.923 ± 0.026	2.964ArgArg: 2.964 ± 0.043	4.043ArgSer: 4.043 ± 0.042	2.322ArgThr: 2.322 ± 0.029	2.659ArgVal: 2.659 ± 0.029	0.506ArgTrp: 0.506 ± 0.013	1.534ArgTyr: 1.534 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	5.884SerAla: 5.884 ± 0.055	0.835SerCys: 0.835 ± 0.017	5.306SerAsp: 5.306 ± 0.059	5.471SerGlu: 5.471 ± 0.059	3.966SerPhe: 3.966 ± 0.043	5.492SerGly: 5.492 ± 0.096	1.934SerHis: 1.934 ± 0.032	4.851SerIle: 4.851 ± 0.043	6.003SerLys: 6.003 ± 0.058	8.303SerLeu: 8.303 ± 0.063	1.845SerMet: 1.845 ± 0.036	4.303SerAsn: 4.303 ± 0.05	4.626SerPro: 4.626 ± 0.066	3.47SerGln: 3.47 ± 0.039	4.16SerArg: 4.16 ± 0.048	10.866SerSer: 10.866 ± 0.161	5.425SerThr: 5.425 ± 0.074	5.428SerVal: 5.428 ± 0.043	0.898SerTrp: 0.898 ± 0.019	2.602SerTyr: 2.602 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	3.664ThrAla: 3.664 ± 0.043	0.572ThrCys: 0.572 ± 0.016	2.99ThrAsp: 2.99 ± 0.078	3.477ThrGlu: 3.477 ± 0.058	2.433ThrPhe: 2.433 ± 0.038	3.289ThrGly: 3.289 ± 0.052	1.095ThrHis: 1.095 ± 0.021	3.115ThrIle: 3.115 ± 0.046	3.595ThrLys: 3.595 ± 0.038	4.766ThrLeu: 4.766 ± 0.047	0.983ThrMet: 0.983 ± 0.02	2.513ThrAsn: 2.513 ± 0.029	3.311ThrPro: 3.311 ± 0.047	1.928ThrGln: 1.928 ± 0.032	2.34ThrArg: 2.34 ± 0.029	5.356ThrSer: 5.356 ± 0.104	3.956ThrThr: 3.956 ± 0.225	3.546ThrVal: 3.546 ± 0.053	0.647ThrTrp: 0.647 ± 0.033	1.74ThrTyr: 1.74 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	4.456ValAla: 4.456 ± 0.047	0.762ValCys: 0.762 ± 0.017	3.913ValAsp: 3.913 ± 0.043	4.147ValGlu: 4.147 ± 0.041	2.867ValPhe: 2.867 ± 0.038	3.388ValGly: 3.388 ± 0.04	1.335ValHis: 1.335 ± 0.025	3.47ValIle: 3.47 ± 0.049	4.194ValLys: 4.194 ± 0.05	5.778ValLeu: 5.778 ± 0.057	1.21ValMet: 1.21 ± 0.024	2.939ValAsn: 2.939 ± 0.033	3.425ValPro: 3.425 ± 0.046	2.1ValGln: 2.1 ± 0.028	2.599ValArg: 2.599 ± 0.035	5.691ValSer: 5.691 ± 0.05	3.498ValThr: 3.498 ± 0.068	4.433ValVal: 4.433 ± 0.056	0.671ValTrp: 0.671 ± 0.017	1.962ValTyr: 1.962 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	0.68TrpAla: 0.68 ± 0.02	0.19TrpCys: 0.19 ± 0.009	0.664TrpAsp: 0.664 ± 0.016	0.625TrpGlu: 0.625 ± 0.016	0.536TrpPhe: 0.536 ± 0.014	0.601TrpGly: 0.601 ± 0.016	0.229TrpHis: 0.229 ± 0.009	0.611TrpIle: 0.611 ± 0.014	0.763TrpLys: 0.763 ± 0.02	1.049TrpLeu: 1.049 ± 0.022	0.219TrpMet: 0.219 ± 0.009	0.581TrpAsn: 0.581 ± 0.014	0.337TrpPro: 0.337 ± 0.011	0.348TrpGln: 0.348 ± 0.011	0.557TrpArg: 0.557 ± 0.016	0.855TrpSer: 0.855 ± 0.019	0.663TrpThr: 0.663 ± 0.04	0.647TrpVal: 0.647 ± 0.015	0.183TrpTrp: 0.183 ± 0.01	0.392TrpTyr: 0.392 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.923TyrAla: 1.923 ± 0.027	0.429TyrCys: 0.429 ± 0.014	2.119TyrAsp: 2.119 ± 0.031	2.082TyrGlu: 2.082 ± 0.029	1.6TyrPhe: 1.6 ± 0.028	2.015TyrGly: 2.015 ± 0.031	0.807TyrHis: 0.807 ± 0.016	1.762TyrIle: 1.762 ± 0.026	2.046TyrLys: 2.046 ± 0.029	3.136TyrLeu: 3.136 ± 0.041	0.704TyrMet: 0.704 ± 0.018	1.69TyrAsn: 1.69 ± 0.03	1.372TyrPro: 1.372 ± 0.026	1.268TyrGln: 1.268 ± 0.024	1.395TyrArg: 1.395 ± 0.023	2.636TyrSer: 2.636 ± 0.035	1.699TyrThr: 1.699 ± 0.033	2.024TyrVal: 2.024 ± 0.028	0.401TyrTrp: 0.401 ± 0.012	1.309TyrTyr: 1.309 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5240 proteins (2783537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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