Clostridium cavendishii DSM 21758

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae; Clostridium; Clostridium cavendishii

Average proteome isoelectric point is 6.58

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4475 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A1M6DE85|A0A1M6DE85_9CLOT Ferrous iron transport protein A OS=Clostridium cavendishii DSM 21758 OX=1121302 GN=SAMN02745163_00706 PE=4 SV=1
GG1 pKa = 6.25ATGVTGATGVTGATGVTGATGITGPLSTGNNAQFITAVSQQLADD45 pKa = 3.43NDD47 pKa = 3.85YY48 pKa = 10.23VEE50 pKa = 5.25LVNSVINGSNITHH63 pKa = 5.99VNGTTDD69 pKa = 3.62IILQGVHH76 pKa = 5.77TYY78 pKa = 9.43YY79 pKa = 11.07VSWEE83 pKa = 3.86IIAIVSVAASVFDD96 pKa = 6.21GILEE100 pKa = 4.46LNDD103 pKa = 3.63QIISGSLGSSGTIQLIGNEE122 pKa = 4.22GAASGSAVFVATKK135 pKa = 10.7VGDD138 pKa = 3.53NVLRR142 pKa = 11.84LQYY145 pKa = 7.61MTSDD149 pKa = 3.22GGINTITSASVSVIEE164 pKa = 4.85LAA166 pKa = 4.27

Molecular weight:
16.59 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A1M6TLR2|A0A1M6TLR2_9CLOT Chromosomal replication initiator protein DnaA OS=Clostridium cavendishii DSM 21758 OX=1121302 GN=dnaA PE=3 SV=1
MM1 pKa = 7.14SRR3 pKa = 11.84EE4 pKa = 4.04MKK6 pKa = 10.47KK7 pKa = 10.24GGPRR11 pKa = 11.84VRR13 pKa = 11.84RR14 pKa = 11.84SKK16 pKa = 10.87RR17 pKa = 11.84KK18 pKa = 8.2VCAFCVEE25 pKa = 3.91KK26 pKa = 11.26AEE28 pKa = 4.82AIDD31 pKa = 3.83YY32 pKa = 11.15KK33 pKa = 11.19DD34 pKa = 3.31VTKK37 pKa = 10.63LRR39 pKa = 11.84KK40 pKa = 9.42YY41 pKa = 7.69VTEE44 pKa = 4.22RR45 pKa = 11.84GKK47 pKa = 10.15ILPRR51 pKa = 11.84RR52 pKa = 11.84ISGTCAKK59 pKa = 9.97HH60 pKa = 5.6QRR62 pKa = 11.84QLTDD66 pKa = 4.2AIKK69 pKa = 10.26RR70 pKa = 11.84SRR72 pKa = 11.84NIALLPFSTDD82 pKa = 2.6

Molecular weight:
9.49 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4475

0

4475

1407850

39

3646

314.6

35.65

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.277 ± 0.037

1.13 ± 0.016

5.548 ± 0.032

7.393 ± 0.044

4.579 ± 0.026

6.085 ± 0.039

1.254 ± 0.012

10.195 ± 0.051

9.441 ± 0.039

9.089 ± 0.036

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.44 ± 0.02

6.946 ± 0.04

2.629 ± 0.023

2.233 ± 0.017

3.151 ± 0.025

6.324 ± 0.033

4.943 ± 0.034

6.359 ± 0.03

0.705 ± 0.011

4.282 ± 0.025

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski