Amino acid dipepetide frequency for Fulvimarina endophytica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.648AlaAla: 15.648 ± 0.156	1.042AlaCys: 1.042 ± 0.03	7.232AlaAsp: 7.232 ± 0.088	8.222AlaGlu: 8.222 ± 0.092	4.862AlaPhe: 4.862 ± 0.066	11.443AlaGly: 11.443 ± 0.161	2.025AlaHis: 2.025 ± 0.043	7.217AlaIle: 7.217 ± 0.081	3.795AlaLys: 3.795 ± 0.074	12.62AlaLeu: 12.62 ± 0.123	3.61AlaMet: 3.61 ± 0.059	2.921AlaAsn: 2.921 ± 0.053	5.295AlaPro: 5.295 ± 0.079	3.295AlaGln: 3.295 ± 0.059	8.974AlaArg: 8.974 ± 0.11	7.651AlaSer: 7.651 ± 0.088	5.641AlaThr: 5.641 ± 0.085	8.386AlaVal: 8.386 ± 0.084	1.254AlaTrp: 1.254 ± 0.032	2.581AlaTyr: 2.581 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.887CysAla: 0.887 ± 0.029	0.08CysCys: 0.08 ± 0.008	0.529CysAsp: 0.529 ± 0.02	0.542CysGlu: 0.542 ± 0.022	0.286CysPhe: 0.286 ± 0.016	0.93CysGly: 0.93 ± 0.03	0.2CysHis: 0.2 ± 0.014	0.327CysIle: 0.327 ± 0.016	0.155CysLys: 0.155 ± 0.011	0.837CysLeu: 0.837 ± 0.027	0.129CysMet: 0.129 ± 0.011	0.159CysAsn: 0.159 ± 0.012	0.402CysPro: 0.402 ± 0.018	0.193CysGln: 0.193 ± 0.011	0.613CysArg: 0.613 ± 0.023	0.391CysSer: 0.391 ± 0.018	0.35CysThr: 0.35 ± 0.019	0.534CysVal: 0.534 ± 0.021	0.087CysTrp: 0.087 ± 0.009	0.17CysTyr: 0.17 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.286AspAla: 7.286 ± 0.103	0.478AspCys: 0.478 ± 0.02	3.367AspAsp: 3.367 ± 0.071	4.329AspGlu: 4.329 ± 0.076	2.195AspPhe: 2.195 ± 0.049	5.736AspGly: 5.736 ± 0.089	1.36AspHis: 1.36 ± 0.039	3.06AspIle: 3.06 ± 0.062	1.547AspLys: 1.547 ± 0.039	6.698AspLeu: 6.698 ± 0.085	1.35AspMet: 1.35 ± 0.035	1.176AspAsn: 1.176 ± 0.032	3.646AspPro: 3.646 ± 0.06	1.709AspGln: 1.709 ± 0.037	5.154AspArg: 5.154 ± 0.078	1.848AspSer: 1.848 ± 0.037	2.549AspThr: 2.549 ± 0.058	4.167AspVal: 4.167 ± 0.067	0.955AspTrp: 0.955 ± 0.026	1.549AspTyr: 1.549 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	9.221GluAla: 9.221 ± 0.12	0.335GluCys: 0.335 ± 0.018	3.697GluAsp: 3.697 ± 0.065	4.067GluGlu: 4.067 ± 0.063	1.798GluPhe: 1.798 ± 0.039	5.139GluGly: 5.139 ± 0.064	1.111GluHis: 1.111 ± 0.032	4.041GluIle: 4.041 ± 0.066	2.268GluLys: 2.268 ± 0.056	5.023GluLeu: 5.023 ± 0.072	1.597GluMet: 1.597 ± 0.037	1.818GluAsn: 1.818 ± 0.041	3.145GluPro: 3.145 ± 0.048	1.653GluGln: 1.653 ± 0.043	6.104GluArg: 6.104 ± 0.086	2.537GluSer: 2.537 ± 0.05	4.834GluThr: 4.834 ± 0.073	3.884GluVal: 3.884 ± 0.056	0.74GluTrp: 0.74 ± 0.027	0.917GluTyr: 0.917 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.841PheAla: 4.841 ± 0.074	0.389PheCys: 0.389 ± 0.019	2.806PheAsp: 2.806 ± 0.051	2.578PheGlu: 2.578 ± 0.053	1.47PhePhe: 1.47 ± 0.042	3.904PheGly: 3.904 ± 0.063	0.674PheHis: 0.674 ± 0.028	1.517PheIle: 1.517 ± 0.039	0.941PheLys: 0.941 ± 0.027	3.669PheLeu: 3.669 ± 0.08	0.835PheMet: 0.835 ± 0.025	0.871PheAsn: 0.871 ± 0.027	1.505PhePro: 1.505 ± 0.039	1.022PheGln: 1.022 ± 0.033	2.229PheArg: 2.229 ± 0.045	2.39PheSer: 2.39 ± 0.051	1.857PheThr: 1.857 ± 0.042	3.197PheVal: 3.197 ± 0.053	0.518PheTrp: 0.518 ± 0.028	0.879PheTyr: 0.879 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.771GlyAla: 9.771 ± 0.136	0.777GlyCys: 0.777 ± 0.028	4.927GlyAsp: 4.927 ± 0.078	6.145GlyGlu: 6.145 ± 0.08	3.8GlyPhe: 3.8 ± 0.066	7.83GlyGly: 7.83 ± 0.159	1.865GlyHis: 1.865 ± 0.047	4.698GlyIle: 4.698 ± 0.071	2.864GlyLys: 2.864 ± 0.058	9.084GlyLeu: 9.084 ± 0.098	2.279GlyMet: 2.279 ± 0.046	2.064GlyAsn: 2.064 ± 0.058	3.736GlyPro: 3.736 ± 0.061	2.585GlyGln: 2.585 ± 0.054	6.884GlyArg: 6.884 ± 0.079	5.468GlySer: 5.468 ± 0.11	5.064GlyThr: 5.064 ± 0.089	5.723GlyVal: 5.723 ± 0.076	1.261GlyTrp: 1.261 ± 0.033	2.198GlyTyr: 2.198 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.139HisAla: 2.139 ± 0.043	0.206HisCys: 0.206 ± 0.014	1.17HisAsp: 1.17 ± 0.038	1.113HisGlu: 1.113 ± 0.034	0.759HisPhe: 0.759 ± 0.026	1.824HisGly: 1.824 ± 0.047	0.531HisHis: 0.531 ± 0.026	0.738HisIle: 0.738 ± 0.025	0.402HisLys: 0.402 ± 0.02	2.03HisLeu: 2.03 ± 0.045	0.453HisMet: 0.453 ± 0.021	0.358HisAsn: 0.358 ± 0.015	1.211HisPro: 1.211 ± 0.03	0.511HisGln: 0.511 ± 0.021	1.434HisArg: 1.434 ± 0.032	0.923HisSer: 0.923 ± 0.028	0.717HisThr: 0.717 ± 0.023	1.406HisVal: 1.406 ± 0.036	0.249HisTrp: 0.249 ± 0.015	0.48HisTyr: 0.48 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.716IleAla: 7.716 ± 0.082	0.481IleCys: 0.481 ± 0.019	3.818IleAsp: 3.818 ± 0.052	4.247IleGlu: 4.247 ± 0.067	1.763IlePhe: 1.763 ± 0.048	5.384IleGly: 5.384 ± 0.078	0.871IleHis: 0.871 ± 0.025	1.928IleIle: 1.928 ± 0.045	1.135IleLys: 1.135 ± 0.034	4.922IleLeu: 4.922 ± 0.082	0.923IleMet: 0.923 ± 0.027	1.152IleAsn: 1.152 ± 0.034	2.165IlePro: 2.165 ± 0.042	1.167IleGln: 1.167 ± 0.033	3.29IleArg: 3.29 ± 0.054	2.703IleSer: 2.703 ± 0.049	2.354IleThr: 2.354 ± 0.047	4.734IleVal: 4.734 ± 0.06	0.536IleTrp: 0.536 ± 0.025	1.043IleTyr: 1.043 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	4.202LysAla: 4.202 ± 0.08	0.126LysCys: 0.126 ± 0.011	1.658LysAsp: 1.658 ± 0.043	1.517LysGlu: 1.517 ± 0.037	0.719LysPhe: 0.719 ± 0.026	2.558LysGly: 2.558 ± 0.045	0.495LysHis: 0.495 ± 0.021	1.56LysIle: 1.56 ± 0.035	1.027LysLys: 1.027 ± 0.034	2.815LysLeu: 2.815 ± 0.054	0.652LysMet: 0.652 ± 0.025	0.753LysAsn: 0.753 ± 0.024	1.914LysPro: 1.914 ± 0.051	0.812LysGln: 0.812 ± 0.025	2.488LysArg: 2.488 ± 0.047	1.809LysSer: 1.809 ± 0.044	1.945LysThr: 1.945 ± 0.037	2.155LysVal: 2.155 ± 0.05	0.299LysTrp: 0.299 ± 0.016	0.449LysTyr: 0.449 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.306LeuAla: 13.306 ± 0.144	0.828LeuCys: 0.828 ± 0.027	6.297LeuAsp: 6.297 ± 0.08	5.199LeuGlu: 5.199 ± 0.071	3.854LeuPhe: 3.854 ± 0.069	8.307LeuGly: 8.307 ± 0.092	1.599LeuHis: 1.599 ± 0.036	4.581LeuIle: 4.581 ± 0.076	3.548LeuLys: 3.548 ± 0.061	8.936LeuLeu: 8.936 ± 0.116	2.061LeuMet: 2.061 ± 0.043	2.375LeuAsn: 2.375 ± 0.048	5.061LeuPro: 5.061 ± 0.074	2.47LeuGln: 2.47 ± 0.043	6.39LeuArg: 6.39 ± 0.085	7.172LeuSer: 7.172 ± 0.083	5.567LeuThr: 5.567 ± 0.074	7.788LeuVal: 7.788 ± 0.09	0.974LeuTrp: 0.974 ± 0.029	1.98LeuTyr: 1.98 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.078MetAla: 3.078 ± 0.051	0.129MetCys: 0.129 ± 0.01	1.22MetAsp: 1.22 ± 0.032	1.189MetGlu: 1.189 ± 0.03	0.689MetPhe: 0.689 ± 0.026	1.792MetGly: 1.792 ± 0.044	0.362MetHis: 0.362 ± 0.017	1.427MetIle: 1.427 ± 0.041	0.938MetLys: 0.938 ± 0.033	2.201MetLeu: 2.201 ± 0.046	0.652MetMet: 0.652 ± 0.027	0.749MetAsn: 0.749 ± 0.023	1.506MetPro: 1.506 ± 0.037	0.718MetGln: 0.718 ± 0.027	1.939MetArg: 1.939 ± 0.035	1.725MetSer: 1.725 ± 0.036	1.882MetThr: 1.882 ± 0.04	1.579MetVal: 1.579 ± 0.038	0.168MetTrp: 0.168 ± 0.011	0.243MetTyr: 0.243 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.206AsnAla: 3.206 ± 0.058	0.194AsnCys: 0.194 ± 0.013	1.45AsnAsp: 1.45 ± 0.043	1.444AsnGlu: 1.444 ± 0.032	0.888AsnPhe: 0.888 ± 0.028	2.486AsnGly: 2.486 ± 0.062	0.452AsnHis: 0.452 ± 0.02	1.18AsnIle: 1.18 ± 0.033	0.537AsnLys: 0.537 ± 0.021	2.447AsnLeu: 2.447 ± 0.052	0.543AsnMet: 0.543 ± 0.02	0.575AsnAsn: 0.575 ± 0.027	1.62AsnPro: 1.62 ± 0.036	0.718AsnGln: 0.718 ± 0.029	1.834AsnArg: 1.834 ± 0.039	1.17AsnSer: 1.17 ± 0.036	1.175AsnThr: 1.175 ± 0.038	1.783AsnVal: 1.783 ± 0.043	0.35AsnTrp: 0.35 ± 0.017	0.598AsnTyr: 0.598 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.841ProAla: 5.841 ± 0.081	0.313ProCys: 0.313 ± 0.016	3.626ProAsp: 3.626 ± 0.062	3.596ProGlu: 3.596 ± 0.053	2.187ProPhe: 2.187 ± 0.047	4.303ProGly: 4.303 ± 0.059	0.992ProHis: 0.992 ± 0.032	2.576ProIle: 2.576 ± 0.05	1.669ProLys: 1.669 ± 0.04	4.332ProLeu: 4.332 ± 0.063	1.155ProMet: 1.155 ± 0.032	1.403ProAsn: 1.403 ± 0.03	2.112ProPro: 2.112 ± 0.051	1.555ProGln: 1.555 ± 0.036	2.889ProArg: 2.889 ± 0.056	3.168ProSer: 3.168 ± 0.049	2.275ProThr: 2.275 ± 0.047	4.14ProVal: 4.14 ± 0.051	0.518ProTrp: 0.518 ± 0.019	1.069ProTyr: 1.069 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.567GlnAla: 3.567 ± 0.069	0.181GlnCys: 0.181 ± 0.014	1.45GlnAsp: 1.45 ± 0.036	1.452GlnGlu: 1.452 ± 0.042	0.913GlnPhe: 0.913 ± 0.028	2.037GlnGly: 2.037 ± 0.044	0.477GlnHis: 0.477 ± 0.022	1.775GlnIle: 1.775 ± 0.038	0.937GlnLys: 0.937 ± 0.029	2.321GlnLeu: 2.321 ± 0.044	0.812GlnMet: 0.812 ± 0.025	0.862GlnAsn: 0.862 ± 0.029	1.474GlnPro: 1.474 ± 0.036	0.845GlnGln: 0.845 ± 0.038	2.121GlnArg: 2.121 ± 0.048	1.93GlnSer: 1.93 ± 0.043	1.877GlnThr: 1.877 ± 0.044	1.854GlnVal: 1.854 ± 0.041	0.319GlnTrp: 0.319 ± 0.016	0.516GlnTyr: 0.516 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	7.768ArgAla: 7.768 ± 0.097	0.484ArgCys: 0.484 ± 0.02	4.252ArgAsp: 4.252 ± 0.066	4.922ArgGlu: 4.922 ± 0.072	3.25ArgPhe: 3.25 ± 0.058	5.011ArgGly: 5.011 ± 0.07	1.665ArgHis: 1.665 ± 0.036	4.342ArgIle: 4.342 ± 0.062	2.248ArgLys: 2.248 ± 0.049	8.188ArgLeu: 8.188 ± 0.091	2.035ArgMet: 2.035 ± 0.039	1.854ArgAsn: 1.854 ± 0.041	3.759ArgPro: 3.759 ± 0.055	2.541ArgGln: 2.541 ± 0.045	6.261ArgArg: 6.261 ± 0.094	4.606ArgSer: 4.606 ± 0.074	3.873ArgThr: 3.873 ± 0.057	4.511ArgVal: 4.511 ± 0.057	0.867ArgTrp: 0.867 ± 0.027	1.69ArgTyr: 1.69 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	6.893SerAla: 6.893 ± 0.092	0.397SerCys: 0.397 ± 0.019	3.477SerAsp: 3.477 ± 0.059	3.726SerGlu: 3.726 ± 0.059	2.44SerPhe: 2.44 ± 0.054	6.256SerGly: 6.256 ± 0.097	1.06SerHis: 1.06 ± 0.033	3.074SerIle: 3.074 ± 0.061	1.589SerLys: 1.589 ± 0.04	5.755SerLeu: 5.755 ± 0.081	1.364SerMet: 1.364 ± 0.031	1.488SerAsn: 1.488 ± 0.039	2.865SerPro: 2.865 ± 0.053	1.758SerGln: 1.758 ± 0.035	4.201SerArg: 4.201 ± 0.066	3.465SerSer: 3.465 ± 0.076	2.679SerThr: 2.679 ± 0.06	4.299SerVal: 4.299 ± 0.081	0.655SerTrp: 0.655 ± 0.023	1.247SerTyr: 1.247 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	6.207ThrAla: 6.207 ± 0.08	0.384ThrCys: 0.384 ± 0.02	2.874ThrAsp: 2.874 ± 0.051	2.897ThrGlu: 2.897 ± 0.053	2.017ThrPhe: 2.017 ± 0.041	5.56ThrGly: 5.56 ± 0.093	0.936ThrHis: 0.936 ± 0.028	3.34ThrIle: 3.34 ± 0.059	1.498ThrLys: 1.498 ± 0.041	5.564ThrLeu: 5.564 ± 0.075	1.2ThrMet: 1.2 ± 0.034	1.357ThrAsn: 1.357 ± 0.042	2.967ThrPro: 2.967 ± 0.054	1.364ThrGln: 1.364 ± 0.035	3.506ThrArg: 3.506 ± 0.052	2.984ThrSer: 2.984 ± 0.06	2.742ThrThr: 2.742 ± 0.057	4.428ThrVal: 4.428 ± 0.065	0.573ThrTrp: 0.573 ± 0.024	1.184ThrTyr: 1.184 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	8.661ValAla: 8.661 ± 0.098	0.648ValCys: 0.648 ± 0.025	4.229ValAsp: 4.229 ± 0.06	4.857ValGlu: 4.857 ± 0.063	2.926ValPhe: 2.926 ± 0.051	5.607ValGly: 5.607 ± 0.066	1.289ValHis: 1.289 ± 0.034	3.549ValIle: 3.549 ± 0.069	2.006ValLys: 2.006 ± 0.047	7.364ValLeu: 7.364 ± 0.093	1.814ValMet: 1.814 ± 0.039	1.822ValAsn: 1.822 ± 0.045	3.701ValPro: 3.701 ± 0.058	1.721ValGln: 1.721 ± 0.037	4.94ValArg: 4.94 ± 0.062	4.816ValSer: 4.816 ± 0.078	4.493ValThr: 4.493 ± 0.062	5.932ValVal: 5.932 ± 0.09	0.813ValTrp: 0.813 ± 0.027	1.474ValTyr: 1.474 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.043TrpAla: 1.043 ± 0.03	0.127TrpCys: 0.127 ± 0.01	0.551TrpAsp: 0.551 ± 0.022	0.525TrpGlu: 0.525 ± 0.023	0.491TrpPhe: 0.491 ± 0.021	0.758TrpGly: 0.758 ± 0.024	0.265TrpHis: 0.265 ± 0.013	0.622TrpIle: 0.622 ± 0.026	0.352TrpLys: 0.352 ± 0.016	1.368TrpLeu: 1.368 ± 0.035	0.353TrpMet: 0.353 ± 0.016	0.397TrpAsn: 0.397 ± 0.019	0.624TrpPro: 0.624 ± 0.024	0.448TrpGln: 0.448 ± 0.02	1.055TrpArg: 1.055 ± 0.031	0.822TrpSer: 0.822 ± 0.029	0.772TrpThr: 0.772 ± 0.03	0.638TrpVal: 0.638 ± 0.024	0.198TrpTrp: 0.198 ± 0.014	0.252TrpTyr: 0.252 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.433TyrAla: 2.433 ± 0.051	0.202TyrCys: 0.202 ± 0.011	1.532TyrAsp: 1.532 ± 0.038	1.36TyrGlu: 1.36 ± 0.039	0.784TyrPhe: 0.784 ± 0.025	2.158TyrGly: 2.158 ± 0.042	0.426TyrHis: 0.426 ± 0.019	0.777TyrIle: 0.777 ± 0.028	0.499TyrLys: 0.499 ± 0.021	2.12TyrLeu: 2.12 ± 0.042	0.371TyrMet: 0.371 ± 0.019	0.493TyrAsn: 0.493 ± 0.021	1.008TyrPro: 1.008 ± 0.028	0.636TyrGln: 0.636 ± 0.024	1.822TyrArg: 1.822 ± 0.036	1.11TyrSer: 1.11 ± 0.031	0.935TyrThr: 0.935 ± 0.032	1.524TyrVal: 1.524 ± 0.034	0.329TyrTrp: 0.329 ± 0.016	0.543TyrTyr: 0.543 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3833 proteins (1255505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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