Amino acid dipepetide frequency for Porcine torque teno virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.834AlaAla: 6.834 ± 9.826
0.0AlaCys: 0.0 ± 0.0
3.417AlaAsp: 3.417 ± 4.382
3.417AlaGlu: 3.417 ± 4.382
3.417AlaPhe: 3.417 ± 1.743
4.556AlaGly: 4.556 ± 0.874
3.417AlaHis: 3.417 ± 2.759
5.695AlaIle: 5.695 ± 3.234
4.556AlaLys: 4.556 ± 4.257
2.278AlaLeu: 2.278 ± 3.275
0.0AlaMet: 0.0 ± 0.0
1.139AlaAsn: 1.139 ± 0.581
3.417AlaPro: 3.417 ± 0.819
4.556AlaGln: 4.556 ± 3.807
2.278AlaArg: 2.278 ± 1.162
3.417AlaSer: 3.417 ± 1.743
5.695AlaThr: 5.695 ± 3.234
1.139AlaVal: 1.139 ± 0.581
0.0AlaTrp: 0.0 ± 0.0
4.556AlaTyr: 4.556 ± 2.275
0.0AlaXaa: 0.0 ± 0.0
Cys
2.278CysAla: 2.278 ± 3.275
0.0CysCys: 0.0 ± 0.0
2.278CysAsp: 2.278 ± 1.162
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.278CysGly: 2.278 ± 3.275
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.417CysLys: 3.417 ± 2.759
3.417CysLeu: 3.417 ± 2.759
0.0CysMet: 0.0 ± 0.0
1.139CysAsn: 1.139 ± 0.581
2.278CysPro: 2.278 ± 1.162
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.139CysThr: 1.139 ± 0.581
1.139CysVal: 1.139 ± 0.581
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
11.39AspAla: 11.39 ± 13.526
2.278AspCys: 2.278 ± 1.162
1.139AspAsp: 1.139 ± 0.581
2.278AspGlu: 2.278 ± 1.162
0.0AspPhe: 0.0 ± 0.0
5.695AspGly: 5.695 ± 5.137
1.139AspHis: 1.139 ± 0.581
4.556AspIle: 4.556 ± 2.275
1.139AspLys: 1.139 ± 1.583
1.139AspLeu: 1.139 ± 0.581
2.278AspMet: 2.278 ± 0.955
2.278AspAsn: 2.278 ± 1.162
7.973AspPro: 7.973 ± 2.103
4.556AspGln: 4.556 ± 2.323
2.278AspArg: 2.278 ± 3.275
1.139AspSer: 1.139 ± 0.581
2.278AspThr: 2.278 ± 1.162
1.139AspVal: 1.139 ± 0.581
1.139AspTrp: 1.139 ± 0.581
2.278AspTyr: 2.278 ± 1.162
0.0AspXaa: 0.0 ± 0.0
Glu
2.278GluAla: 2.278 ± 1.162
1.139GluCys: 1.139 ± 0.581
2.278GluAsp: 2.278 ± 3.275
6.834GluGlu: 6.834 ± 1.524
1.139GluPhe: 1.139 ± 0.581
6.834GluGly: 6.834 ± 2.665
0.0GluHis: 0.0 ± 0.0
1.139GluIle: 1.139 ± 1.583
9.112GluLys: 9.112 ± 3.396
4.556GluLeu: 4.556 ± 2.323
1.139GluMet: 1.139 ± 0.581
2.278GluAsn: 2.278 ± 3.167
3.417GluPro: 3.417 ± 1.743
2.278GluGln: 2.278 ± 1.119
6.834GluArg: 6.834 ± 4.556
1.139GluSer: 1.139 ± 0.581
3.417GluThr: 3.417 ± 1.743
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.139GluTyr: 1.139 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
2.278PheAla: 2.278 ± 1.162
2.278PheCys: 2.278 ± 3.275
2.278PheAsp: 2.278 ± 3.275
1.139PheGlu: 1.139 ± 0.581
2.278PhePhe: 2.278 ± 1.162
1.139PheGly: 1.139 ± 0.581
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
2.278PheLys: 2.278 ± 1.162
1.139PheLeu: 1.139 ± 0.581
1.139PheMet: 1.139 ± 1.583
1.139PheAsn: 1.139 ± 0.581
1.139PhePro: 1.139 ± 0.581
2.278PheGln: 2.278 ± 1.162
5.695PheArg: 5.695 ± 2.904
1.139PheSer: 1.139 ± 1.583
1.139PheThr: 1.139 ± 0.581
2.278PheVal: 2.278 ± 1.162
2.278PheTrp: 2.278 ± 1.162
3.417PheTyr: 3.417 ± 1.743
0.0PheXaa: 0.0 ± 0.0
Gly
2.278GlyAla: 2.278 ± 1.162
3.417GlyCys: 3.417 ± 2.759
9.112GlyAsp: 9.112 ± 5.907
2.278GlyGlu: 2.278 ± 1.119
1.139GlyPhe: 1.139 ± 0.581
13.667GlyGly: 13.667 ± 9.675
3.417GlyHis: 3.417 ± 0.819
5.695GlyIle: 5.695 ± 1.847
2.278GlyLys: 2.278 ± 1.119
5.695GlyLeu: 5.695 ± 1.847
1.139GlyMet: 1.139 ± 0.581
2.278GlyAsn: 2.278 ± 1.162
1.139GlyPro: 1.139 ± 0.581
3.417GlyGln: 3.417 ± 1.743
1.139GlyArg: 1.139 ± 0.581
5.695GlySer: 5.695 ± 2.904
3.417GlyThr: 3.417 ± 2.759
4.556GlyVal: 4.556 ± 0.874
4.556GlyTrp: 4.556 ± 2.323
2.278GlyTyr: 2.278 ± 1.162
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.139HisAsp: 1.139 ± 0.581
4.556HisGlu: 4.556 ± 3.807
0.0HisPhe: 0.0 ± 0.0
5.695HisGly: 5.695 ± 1.847
1.139HisHis: 1.139 ± 0.581
2.278HisIle: 2.278 ± 1.119
2.278HisLys: 2.278 ± 1.162
3.417HisLeu: 3.417 ± 2.759
1.139HisMet: 1.139 ± 1.583
0.0HisAsn: 0.0 ± 0.0
2.278HisPro: 2.278 ± 1.162
0.0HisGln: 0.0 ± 0.0
1.139HisArg: 1.139 ± 0.581
1.139HisSer: 1.139 ± 0.581
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.139HisTrp: 1.139 ± 0.581
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.278IleAla: 2.278 ± 3.275
0.0IleCys: 0.0 ± 0.0
5.695IleAsp: 5.695 ± 3.234
2.278IleGlu: 2.278 ± 1.162
1.139IlePhe: 1.139 ± 0.581
5.695IleGly: 5.695 ± 1.847
0.0IleHis: 0.0 ± 0.0
1.139IleIle: 1.139 ± 1.583
1.139IleLys: 1.139 ± 0.581
2.278IleLeu: 2.278 ± 1.119
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
4.556IlePro: 4.556 ± 2.323
4.556IleGln: 4.556 ± 2.237
3.417IleArg: 3.417 ± 2.68
2.278IleSer: 2.278 ± 1.162
1.139IleThr: 1.139 ± 0.581
3.417IleVal: 3.417 ± 1.743
1.139IleTrp: 1.139 ± 0.581
1.139IleTyr: 1.139 ± 0.581
0.0IleXaa: 0.0 ± 0.0
Lys
3.417LysAla: 3.417 ± 1.743
2.278LysCys: 2.278 ± 3.275
5.695LysAsp: 5.695 ± 1.847
2.278LysGlu: 2.278 ± 1.119
4.556LysPhe: 4.556 ± 0.874
0.0LysGly: 0.0 ± 0.0
5.695LysHis: 5.695 ± 3.234
2.278LysIle: 2.278 ± 1.162
9.112LysLys: 9.112 ± 3.396
7.973LysLeu: 7.973 ± 2.257
0.0LysMet: 0.0 ± 0.0
2.278LysAsn: 2.278 ± 3.167
3.417LysPro: 3.417 ± 1.743
3.417LysGln: 3.417 ± 0.819
3.417LysArg: 3.417 ± 1.743
2.278LysSer: 2.278 ± 1.119
4.556LysThr: 4.556 ± 0.874
2.278LysVal: 2.278 ± 1.162
0.0LysTrp: 0.0 ± 0.0
4.556LysTyr: 4.556 ± 0.874
0.0LysXaa: 0.0 ± 0.0
Leu
4.556LeuAla: 4.556 ± 3.807
1.139LeuCys: 1.139 ± 0.581
1.139LeuAsp: 1.139 ± 0.581
4.556LeuGlu: 4.556 ± 2.275
5.695LeuPhe: 5.695 ± 1.847
4.556LeuGly: 4.556 ± 2.323
1.139LeuHis: 1.139 ± 1.583
4.556LeuIle: 4.556 ± 2.323
9.112LeuLys: 9.112 ± 2.808
9.112LeuLeu: 9.112 ± 1.473
1.139LeuMet: 1.139 ± 1.048
5.695LeuAsn: 5.695 ± 1.873
2.278LeuPro: 2.278 ± 1.162
3.417LeuGln: 3.417 ± 1.743
4.556LeuArg: 4.556 ± 0.874
9.112LeuSer: 9.112 ± 2.808
5.695LeuThr: 5.695 ± 6.029
1.139LeuVal: 1.139 ± 0.581
0.0LeuTrp: 0.0 ± 0.0
2.278LeuTyr: 2.278 ± 1.119
0.0LeuXaa: 0.0 ± 0.0
Met
1.139MetAla: 1.139 ± 0.581
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
4.556MetGlu: 4.556 ± 3.807
0.0MetPhe: 0.0 ± 0.0
1.139MetGly: 1.139 ± 0.581
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
3.417MetLys: 3.417 ± 1.743
2.278MetLeu: 2.278 ± 1.162
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.139MetPro: 1.139 ± 0.581
1.139MetGln: 1.139 ± 1.583
1.139MetArg: 1.139 ± 0.581
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.139MetVal: 1.139 ± 0.581
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.417AsnAla: 3.417 ± 0.819
0.0AsnCys: 0.0 ± 0.0
1.139AsnAsp: 1.139 ± 0.581
2.278AsnGlu: 2.278 ± 1.119
1.139AsnPhe: 1.139 ± 0.581
1.139AsnGly: 1.139 ± 0.581
0.0AsnHis: 0.0 ± 0.0
2.278AsnIle: 2.278 ± 1.119
1.139AsnLys: 1.139 ± 1.583
4.556AsnLeu: 4.556 ± 0.874
1.139AsnMet: 1.139 ± 0.581
0.0AsnAsn: 0.0 ± 0.0
3.417AsnPro: 3.417 ± 1.743
2.278AsnGln: 2.278 ± 1.162
2.278AsnArg: 2.278 ± 1.119
0.0AsnSer: 0.0 ± 0.0
4.556AsnThr: 4.556 ± 0.874
3.417AsnVal: 3.417 ± 0.819
4.556AsnTrp: 4.556 ± 2.323
1.139AsnTyr: 1.139 ± 0.581
0.0AsnXaa: 0.0 ± 0.0
Pro
2.278ProAla: 2.278 ± 1.119
2.278ProCys: 2.278 ± 1.162
1.139ProAsp: 1.139 ± 0.581
2.278ProGlu: 2.278 ± 1.162
2.278ProPhe: 2.278 ± 1.162
4.556ProGly: 4.556 ± 2.323
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
5.695ProLys: 5.695 ± 1.847
6.834ProLeu: 6.834 ± 3.485
1.139ProMet: 1.139 ± 0.581
1.139ProAsn: 1.139 ± 0.581
6.834ProPro: 6.834 ± 1.725
1.139ProGln: 1.139 ± 1.583
1.139ProArg: 1.139 ± 0.581
4.556ProSer: 4.556 ± 0.874
4.556ProThr: 4.556 ± 0.874
2.278ProVal: 2.278 ± 1.162
4.556ProTrp: 4.556 ± 0.874
3.417ProTyr: 3.417 ± 1.743
0.0ProXaa: 0.0 ± 0.0
Gln
3.417GlnAla: 3.417 ± 4.75
0.0GlnCys: 0.0 ± 0.0
4.556GlnAsp: 4.556 ± 2.323
3.417GlnGlu: 3.417 ± 0.819
1.139GlnPhe: 1.139 ± 0.581
2.278GlnGly: 2.278 ± 1.162
3.417GlnHis: 3.417 ± 1.743
0.0GlnIle: 0.0 ± 0.0
3.417GlnLys: 3.417 ± 1.743
1.139GlnLeu: 1.139 ± 1.583
2.278GlnMet: 2.278 ± 1.162
6.834GlnAsn: 6.834 ± 1.725
1.139GlnPro: 1.139 ± 0.581
0.0GlnGln: 0.0 ± 0.0
4.556GlnArg: 4.556 ± 2.275
2.278GlnSer: 2.278 ± 1.162
2.278GlnThr: 2.278 ± 1.162
0.0GlnVal: 0.0 ± 0.0
5.695GlnTrp: 5.695 ± 1.238
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.417ArgAla: 3.417 ± 2.68
0.0ArgCys: 0.0 ± 0.0
4.556ArgAsp: 4.556 ± 2.237
4.556ArgGlu: 4.556 ± 2.237
2.278ArgPhe: 2.278 ± 1.162
2.278ArgGly: 2.278 ± 1.162
4.556ArgHis: 4.556 ± 2.275
1.139ArgIle: 1.139 ± 0.581
2.278ArgLys: 2.278 ± 1.162
6.834ArgLeu: 6.834 ± 1.725
2.278ArgMet: 2.278 ± 1.647
2.278ArgAsn: 2.278 ± 1.119
3.417ArgPro: 3.417 ± 1.743
1.139ArgGln: 1.139 ± 0.581
29.613ArgArg: 29.613 ± 7.95
1.139ArgSer: 1.139 ± 0.581
4.556ArgThr: 4.556 ± 2.323
1.139ArgVal: 1.139 ± 0.581
5.695ArgTrp: 5.695 ± 1.847
6.834ArgTyr: 6.834 ± 1.725
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
4.556SerAsp: 4.556 ± 0.874
2.278SerGlu: 2.278 ± 1.162
0.0SerPhe: 0.0 ± 0.0
3.417SerGly: 3.417 ± 1.743
1.139SerHis: 1.139 ± 0.581
1.139SerIle: 1.139 ± 0.581
4.556SerLys: 4.556 ± 2.323
5.695SerLeu: 5.695 ± 1.873
0.0SerMet: 0.0 ± 0.0
4.556SerAsn: 4.556 ± 2.323
0.0SerPro: 0.0 ± 0.0
4.556SerGln: 4.556 ± 2.323
4.556SerArg: 4.556 ± 0.874
4.556SerSer: 4.556 ± 2.323
2.278SerThr: 2.278 ± 1.162
2.278SerVal: 2.278 ± 1.162
0.0SerTrp: 0.0 ± 0.0
1.139SerTyr: 1.139 ± 0.581
0.0SerXaa: 0.0 ± 0.0
Thr
4.556ThrAla: 4.556 ± 0.874
2.278ThrCys: 2.278 ± 1.162
3.417ThrAsp: 3.417 ± 2.759
5.695ThrGlu: 5.695 ± 2.904
2.278ThrPhe: 2.278 ± 3.275
6.834ThrGly: 6.834 ± 2.665
0.0ThrHis: 0.0 ± 0.0
2.278ThrIle: 2.278 ± 1.162
3.417ThrLys: 3.417 ± 0.819
3.417ThrLeu: 3.417 ± 1.743
1.139ThrMet: 1.139 ± 0.581
4.556ThrAsn: 4.556 ± 2.323
3.417ThrPro: 3.417 ± 2.68
5.695ThrGln: 5.695 ± 2.904
1.139ThrArg: 1.139 ± 0.581
2.278ThrSer: 2.278 ± 1.162
3.417ThrThr: 3.417 ± 0.819
4.556ThrVal: 4.556 ± 3.807
1.139ThrTrp: 1.139 ± 0.581
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.417ValAla: 3.417 ± 2.759
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.139ValGlu: 1.139 ± 0.581
0.0ValPhe: 0.0 ± 0.0
2.278ValGly: 2.278 ± 1.162
0.0ValHis: 0.0 ± 0.0
5.695ValIle: 5.695 ± 1.238
1.139ValLys: 1.139 ± 0.581
4.556ValLeu: 4.556 ± 2.323
0.0ValMet: 0.0 ± 0.0
1.139ValAsn: 1.139 ± 0.581
1.139ValPro: 1.139 ± 1.583
2.278ValGln: 2.278 ± 1.162
3.417ValArg: 3.417 ± 1.743
1.139ValSer: 1.139 ± 0.581
5.695ValThr: 5.695 ± 1.238
2.278ValVal: 2.278 ± 1.162
0.0ValTrp: 0.0 ± 0.0
1.139ValTyr: 1.139 ± 0.581
0.0ValXaa: 0.0 ± 0.0
Trp
1.139TrpAla: 1.139 ± 0.581
0.0TrpCys: 0.0 ± 0.0
2.278TrpAsp: 2.278 ± 1.162
0.0TrpGlu: 0.0 ± 0.0
2.278TrpPhe: 2.278 ± 1.162
3.417TrpGly: 3.417 ± 1.743
0.0TrpHis: 0.0 ± 0.0
2.278TrpIle: 2.278 ± 1.119
0.0TrpLys: 0.0 ± 0.0
4.556TrpLeu: 4.556 ± 2.275
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
4.556TrpPro: 4.556 ± 2.323
0.0TrpGln: 0.0 ± 0.0
5.695TrpArg: 5.695 ± 2.904
2.278TrpSer: 2.278 ± 1.162
4.556TrpThr: 4.556 ± 0.874
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.417TyrAla: 3.417 ± 1.743
2.278TyrCys: 2.278 ± 3.275
2.278TyrAsp: 2.278 ± 1.162
1.139TyrGlu: 1.139 ± 0.581
5.695TyrPhe: 5.695 ± 1.238
1.139TyrGly: 1.139 ± 0.581
2.278TyrHis: 2.278 ± 1.162
1.139TyrIle: 1.139 ± 0.581
0.0TyrLys: 0.0 ± 0.0
1.139TyrLeu: 1.139 ± 1.583
0.0TyrMet: 0.0 ± 0.0
1.139TyrAsn: 1.139 ± 0.581
1.139TyrPro: 1.139 ± 0.581
1.139TyrGln: 1.139 ± 0.581
5.695TyrArg: 5.695 ± 1.238
1.139TyrSer: 1.139 ± 0.581
1.139TyrThr: 1.139 ± 0.581
2.278TyrVal: 2.278 ± 1.162
1.139TyrTrp: 1.139 ± 0.581
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (879 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski