Amino acid dipepetide frequency for Peanut bud necrosis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.391AlaAla: 2.391 ± 1.329
1.594AlaCys: 1.594 ± 0.351
2.989AlaAsp: 2.989 ± 0.999
2.192AlaGlu: 2.192 ± 1.016
2.192AlaPhe: 2.192 ± 0.992
1.992AlaGly: 1.992 ± 0.458
0.797AlaHis: 0.797 ± 0.359
2.789AlaIle: 2.789 ± 0.336
3.786AlaLys: 3.786 ± 0.798
2.789AlaLeu: 2.789 ± 0.456
1.594AlaMet: 1.594 ± 0.931
2.391AlaAsn: 2.391 ± 0.777
1.793AlaPro: 1.793 ± 0.612
0.398AlaGln: 0.398 ± 0.18
1.594AlaArg: 1.594 ± 1.081
3.985AlaSer: 3.985 ± 1.547
2.192AlaThr: 2.192 ± 0.36
2.989AlaVal: 2.989 ± 0.56
0.398AlaTrp: 0.398 ± 0.233
1.793AlaTyr: 1.793 ± 0.515
0.0AlaXaa: 0.0 ± 0.0
Cys
1.395CysAla: 1.395 ± 0.327
0.398CysCys: 0.398 ± 0.352
0.797CysAsp: 0.797 ± 0.611
1.395CysGlu: 1.395 ± 0.223
1.395CysPhe: 1.395 ± 0.382
0.996CysGly: 0.996 ± 0.991
0.398CysHis: 0.398 ± 0.352
1.992CysIle: 1.992 ± 0.488
1.992CysLys: 1.992 ± 0.954
2.192CysLeu: 2.192 ± 0.487
0.797CysMet: 0.797 ± 0.476
0.797CysAsn: 0.797 ± 0.635
0.598CysPro: 0.598 ± 0.349
0.199CysGln: 0.199 ± 0.236
1.395CysArg: 1.395 ± 0.327
1.992CysSer: 1.992 ± 1.154
0.996CysThr: 0.996 ± 0.869
1.992CysVal: 1.992 ± 1.554
0.199CysTrp: 0.199 ± 0.116
0.797CysTyr: 0.797 ± 0.435
0.0CysXaa: 0.0 ± 0.0
Asp
2.192AspAla: 2.192 ± 0.261
1.992AspCys: 1.992 ± 0.521
3.188AspAsp: 3.188 ± 0.703
3.985AspGlu: 3.985 ± 0.63
3.786AspPhe: 3.786 ± 1.191
1.793AspGly: 1.793 ± 0.701
0.398AspHis: 0.398 ± 0.18
6.575AspIle: 6.575 ± 0.693
3.786AspLys: 3.786 ± 1.849
5.38AspLeu: 5.38 ± 0.91
1.594AspMet: 1.594 ± 0.518
2.989AspAsn: 2.989 ± 0.729
1.594AspPro: 1.594 ± 0.606
2.391AspGln: 2.391 ± 0.76
2.391AspArg: 2.391 ± 0.917
3.786AspSer: 3.786 ± 1.116
3.387AspThr: 3.387 ± 1.339
4.184AspVal: 4.184 ± 0.733
0.598AspTrp: 0.598 ± 0.296
2.789AspTyr: 2.789 ± 0.381
0.0AspXaa: 0.0 ± 0.0
Glu
2.989GluAla: 2.989 ± 0.865
1.793GluCys: 1.793 ± 0.303
3.188GluAsp: 3.188 ± 0.43
5.38GluGlu: 5.38 ± 1.173
3.188GluPhe: 3.188 ± 0.432
2.391GluGly: 2.391 ± 0.792
0.996GluHis: 0.996 ± 0.799
4.981GluIle: 4.981 ± 1.202
6.376GluLys: 6.376 ± 0.49
6.177GluLeu: 6.177 ± 1.021
3.387GluMet: 3.387 ± 0.58
4.383GluAsn: 4.383 ± 0.571
0.598GluPro: 0.598 ± 0.402
1.395GluGln: 1.395 ± 0.614
2.192GluArg: 2.192 ± 0.819
5.38GluSer: 5.38 ± 0.942
2.789GluThr: 2.789 ± 0.89
3.387GluVal: 3.387 ± 0.534
0.398GluTrp: 0.398 ± 0.18
2.59GluTyr: 2.59 ± 1.026
0.0GluXaa: 0.0 ± 0.0
Phe
2.59PheAla: 2.59 ± 0.505
1.793PheCys: 1.793 ± 0.758
2.59PheAsp: 2.59 ± 0.64
1.793PheGlu: 1.793 ± 0.597
2.391PhePhe: 2.391 ± 1.078
1.594PheGly: 1.594 ± 0.372
0.797PheHis: 0.797 ± 0.456
3.188PheIle: 3.188 ± 0.553
6.177PheLys: 6.177 ± 1.056
5.18PheLeu: 5.18 ± 1.027
1.594PheMet: 1.594 ± 0.434
2.789PheAsn: 2.789 ± 0.608
1.992PhePro: 1.992 ± 0.447
1.594PheGln: 1.594 ± 0.68
1.594PheArg: 1.594 ± 0.732
4.583PheSer: 4.583 ± 0.842
1.992PheThr: 1.992 ± 0.473
1.992PheVal: 1.992 ± 0.521
0.0PheTrp: 0.0 ± 0.0
1.594PheTyr: 1.594 ± 0.634
0.0PheXaa: 0.0 ± 0.0
Gly
1.395GlyAla: 1.395 ± 0.733
1.594GlyCys: 1.594 ± 0.967
2.391GlyAsp: 2.391 ± 0.72
2.391GlyGlu: 2.391 ± 0.963
1.594GlyPhe: 1.594 ± 0.592
1.195GlyGly: 1.195 ± 0.615
0.797GlyHis: 0.797 ± 0.359
3.586GlyIle: 3.586 ± 0.676
3.387GlyLys: 3.387 ± 0.73
3.786GlyLeu: 3.786 ± 0.765
0.797GlyMet: 0.797 ± 0.259
3.985GlyAsn: 3.985 ± 0.642
1.395GlyPro: 1.395 ± 0.745
0.996GlyGln: 0.996 ± 0.354
0.797GlyArg: 0.797 ± 0.705
3.387GlySer: 3.387 ± 0.464
1.793GlyThr: 1.793 ± 1.054
3.188GlyVal: 3.188 ± 0.657
0.398GlyTrp: 0.398 ± 0.352
1.992GlyTyr: 1.992 ± 0.702
0.0GlyXaa: 0.0 ± 0.0
His
0.598HisAla: 0.598 ± 0.349
0.797HisCys: 0.797 ± 0.359
1.395HisAsp: 1.395 ± 0.341
0.797HisGlu: 0.797 ± 0.705
2.391HisPhe: 2.391 ± 0.599
0.398HisGly: 0.398 ± 0.352
0.398HisHis: 0.398 ± 0.18
0.797HisIle: 0.797 ± 0.837
0.996HisLys: 0.996 ± 0.582
1.793HisLeu: 1.793 ± 0.536
0.199HisMet: 0.199 ± 0.116
1.195HisAsn: 1.195 ± 0.587
0.996HisPro: 0.996 ± 0.354
0.398HisGln: 0.398 ± 0.352
0.199HisArg: 0.199 ± 0.116
1.992HisSer: 1.992 ± 0.652
0.996HisThr: 0.996 ± 0.234
0.996HisVal: 0.996 ± 0.354
0.199HisTrp: 0.199 ± 0.116
0.598HisTyr: 0.598 ± 0.318
0.0HisXaa: 0.0 ± 0.0
Ile
3.188IleAla: 3.188 ± 0.776
1.992IleCys: 1.992 ± 0.805
5.778IleAsp: 5.778 ± 0.863
5.18IleGlu: 5.18 ± 1.149
3.188IlePhe: 3.188 ± 0.883
2.391IleGly: 2.391 ± 0.64
1.793IleHis: 1.793 ± 0.536
5.778IleIle: 5.778 ± 0.572
10.56IleLys: 10.56 ± 0.98
6.177IleLeu: 6.177 ± 0.646
2.192IleMet: 2.192 ± 0.81
6.376IleAsn: 6.376 ± 1.207
3.786IlePro: 3.786 ± 0.932
4.981IleGln: 4.981 ± 0.873
1.395IleArg: 1.395 ± 0.758
5.977IleSer: 5.977 ± 0.878
4.583IleThr: 4.583 ± 1.316
3.387IleVal: 3.387 ± 0.861
0.996IleTrp: 0.996 ± 0.401
2.391IleTyr: 2.391 ± 0.76
0.0IleXaa: 0.0 ± 0.0
Lys
5.38LysAla: 5.38 ± 1.246
1.793LysCys: 1.793 ± 0.699
4.184LysAsp: 4.184 ± 0.964
6.177LysGlu: 6.177 ± 1.142
3.387LysPhe: 3.387 ± 0.526
4.583LysGly: 4.583 ± 0.874
1.594LysHis: 1.594 ± 0.518
7.173LysIle: 7.173 ± 0.835
8.169LysLys: 8.169 ± 0.876
7.372LysLeu: 7.372 ± 1.81
3.586LysMet: 3.586 ± 0.481
4.981LysAsn: 4.981 ± 1.284
2.391LysPro: 2.391 ± 0.761
3.188LysGln: 3.188 ± 1.573
3.188LysArg: 3.188 ± 0.915
8.767LysSer: 8.767 ± 2.259
6.575LysThr: 6.575 ± 2.295
4.383LysVal: 4.383 ± 0.905
0.797LysTrp: 0.797 ± 0.259
3.387LysTyr: 3.387 ± 0.738
0.0LysXaa: 0.0 ± 0.0
Leu
4.782LeuAla: 4.782 ± 0.778
1.195LeuCys: 1.195 ± 0.343
4.383LeuAsp: 4.383 ± 0.638
6.974LeuGlu: 6.974 ± 0.9
3.985LeuPhe: 3.985 ± 1.05
4.583LeuGly: 4.583 ± 0.889
1.793LeuHis: 1.793 ± 0.793
6.177LeuIle: 6.177 ± 1.34
7.97LeuLys: 7.97 ± 1.229
7.97LeuLeu: 7.97 ± 0.945
4.583LeuMet: 4.583 ± 1.665
6.177LeuAsn: 6.177 ± 0.913
2.192LeuPro: 2.192 ± 1.107
1.793LeuGln: 1.793 ± 0.84
2.391LeuArg: 2.391 ± 0.627
10.56LeuSer: 10.56 ± 1.16
5.18LeuThr: 5.18 ± 0.429
4.583LeuVal: 4.583 ± 2.29
0.598LeuTrp: 0.598 ± 0.707
3.786LeuTyr: 3.786 ± 0.948
0.0LeuXaa: 0.0 ± 0.0
Met
0.598MetAla: 0.598 ± 0.276
0.398MetCys: 0.398 ± 0.289
2.192MetAsp: 2.192 ± 0.595
1.793MetGlu: 1.793 ± 0.409
0.598MetPhe: 0.598 ± 0.296
0.996MetGly: 0.996 ± 0.453
0.797MetHis: 0.797 ± 0.837
3.586MetIle: 3.586 ± 0.33
3.387MetLys: 3.387 ± 1.713
1.195MetLeu: 1.195 ± 0.515
1.992MetMet: 1.992 ± 0.68
2.391MetAsn: 2.391 ± 1.174
1.195MetPro: 1.195 ± 0.306
0.797MetGln: 0.797 ± 0.355
0.996MetArg: 0.996 ± 0.582
5.18MetSer: 5.18 ± 0.85
1.793MetThr: 1.793 ± 0.415
1.992MetVal: 1.992 ± 0.475
0.0MetTrp: 0.0 ± 0.0
1.195MetTyr: 1.195 ± 0.551
0.0MetXaa: 0.0 ± 0.0
Asn
1.992AsnAla: 1.992 ± 0.644
0.996AsnCys: 0.996 ± 0.385
4.583AsnAsp: 4.583 ± 0.559
3.786AsnGlu: 3.786 ± 0.734
3.985AsnPhe: 3.985 ± 0.512
2.59AsnGly: 2.59 ± 0.617
0.598AsnHis: 0.598 ± 0.759
6.177AsnIle: 6.177 ± 1.993
3.985AsnLys: 3.985 ± 0.737
7.77AsnLeu: 7.77 ± 1.279
0.598AsnMet: 0.598 ± 0.349
3.387AsnAsn: 3.387 ± 1.404
1.793AsnPro: 1.793 ± 0.381
3.188AsnGln: 3.188 ± 0.3
1.992AsnArg: 1.992 ± 1.062
3.786AsnSer: 3.786 ± 0.372
4.184AsnThr: 4.184 ± 0.824
3.586AsnVal: 3.586 ± 1.04
0.996AsnTrp: 0.996 ± 0.706
3.188AsnTyr: 3.188 ± 1.154
0.0AsnXaa: 0.0 ± 0.0
Pro
1.395ProAla: 1.395 ± 0.323
0.0ProCys: 0.0 ± 0.0
1.793ProAsp: 1.793 ± 0.718
1.594ProGlu: 1.594 ± 0.656
1.793ProPhe: 1.793 ± 0.536
1.594ProGly: 1.594 ± 0.908
0.0ProHis: 0.0 ± 0.0
3.985ProIle: 3.985 ± 0.795
3.188ProLys: 3.188 ± 0.871
2.391ProLeu: 2.391 ± 0.943
0.996ProMet: 0.996 ± 0.401
2.391ProAsn: 2.391 ± 0.448
0.398ProPro: 0.398 ± 0.471
0.598ProGln: 0.598 ± 0.19
0.398ProArg: 0.398 ± 0.471
2.989ProSer: 2.989 ± 0.447
1.594ProThr: 1.594 ± 1.057
1.594ProVal: 1.594 ± 0.535
0.0ProTrp: 0.0 ± 0.0
1.195ProTyr: 1.195 ± 0.38
0.0ProXaa: 0.0 ± 0.0
Gln
0.398GlnAla: 0.398 ± 0.395
0.598GlnCys: 0.598 ± 0.566
2.192GlnAsp: 2.192 ± 0.363
1.793GlnGlu: 1.793 ± 0.381
0.797GlnPhe: 0.797 ± 0.435
0.598GlnGly: 0.598 ± 0.349
0.398GlnHis: 0.398 ± 0.352
3.387GlnIle: 3.387 ± 0.515
2.789GlnLys: 2.789 ± 0.335
2.192GlnLeu: 2.192 ± 0.36
0.996GlnMet: 0.996 ± 0.453
1.992GlnAsn: 1.992 ± 0.226
0.797GlnPro: 0.797 ± 0.259
0.398GlnGln: 0.398 ± 0.471
0.996GlnArg: 0.996 ± 0.582
4.184GlnSer: 4.184 ± 1.242
1.395GlnThr: 1.395 ± 0.223
2.192GlnVal: 2.192 ± 0.988
0.199GlnTrp: 0.199 ± 0.389
1.395GlnTyr: 1.395 ± 0.296
0.0GlnXaa: 0.0 ± 0.0
Arg
1.195ArgAla: 1.195 ± 0.321
0.0ArgCys: 0.0 ± 0.0
0.996ArgAsp: 0.996 ± 0.453
1.793ArgGlu: 1.793 ± 0.597
0.797ArgPhe: 0.797 ± 0.355
0.797ArgGly: 0.797 ± 0.466
1.395ArgHis: 1.395 ± 0.568
2.192ArgIle: 2.192 ± 0.438
3.387ArgLys: 3.387 ± 0.886
3.786ArgLeu: 3.786 ± 0.628
0.598ArgMet: 0.598 ± 0.488
2.192ArgAsn: 2.192 ± 0.791
0.996ArgPro: 0.996 ± 0.433
1.395ArgGln: 1.395 ± 0.535
0.996ArgArg: 0.996 ± 0.262
3.387ArgSer: 3.387 ± 0.459
1.793ArgThr: 1.793 ± 0.808
1.395ArgVal: 1.395 ± 0.629
0.598ArgTrp: 0.598 ± 0.349
1.594ArgTyr: 1.594 ± 0.488
0.0ArgXaa: 0.0 ± 0.0
Ser
4.981SerAla: 4.981 ± 1.358
1.395SerCys: 1.395 ± 1.058
4.981SerAsp: 4.981 ± 0.772
6.575SerGlu: 6.575 ± 1.15
4.184SerPhe: 4.184 ± 1.564
4.583SerGly: 4.583 ± 0.51
1.793SerHis: 1.793 ± 0.303
8.767SerIle: 8.767 ± 0.588
6.376SerLys: 6.376 ± 0.983
11.357SerLeu: 11.357 ± 0.604
3.188SerMet: 3.188 ± 1.094
5.977SerAsn: 5.977 ± 1.459
2.391SerPro: 2.391 ± 1.331
2.192SerGln: 2.192 ± 0.285
3.387SerArg: 3.387 ± 1.061
9.165SerSer: 9.165 ± 1.619
4.583SerThr: 4.583 ± 0.968
5.778SerVal: 5.778 ± 0.562
0.598SerTrp: 0.598 ± 0.566
3.188SerTyr: 3.188 ± 0.906
0.0SerXaa: 0.0 ± 0.0
Thr
1.195ThrAla: 1.195 ± 0.449
2.192ThrCys: 2.192 ± 0.417
2.789ThrAsp: 2.789 ± 0.886
4.184ThrGlu: 4.184 ± 0.92
3.586ThrPhe: 3.586 ± 0.86
2.59ThrGly: 2.59 ± 0.434
1.195ThrHis: 1.195 ± 0.349
3.985ThrIle: 3.985 ± 0.57
3.786ThrLys: 3.786 ± 1.175
4.583ThrLeu: 4.583 ± 1.337
0.797ThrMet: 0.797 ± 0.389
4.583ThrAsn: 4.583 ± 0.864
1.594ThrPro: 1.594 ± 0.715
1.195ThrGln: 1.195 ± 0.263
0.996ThrArg: 0.996 ± 0.234
5.579ThrSer: 5.579 ± 0.864
2.789ThrThr: 2.789 ± 0.88
3.188ThrVal: 3.188 ± 1.43
0.398ThrTrp: 0.398 ± 0.395
2.192ThrTyr: 2.192 ± 0.636
0.0ThrXaa: 0.0 ± 0.0
Val
2.59ValAla: 2.59 ± 0.715
1.195ValCys: 1.195 ± 0.343
5.18ValAsp: 5.18 ± 1.663
3.985ValGlu: 3.985 ± 0.728
2.391ValPhe: 2.391 ± 0.461
2.391ValGly: 2.391 ± 1.177
1.395ValHis: 1.395 ± 0.629
3.387ValIle: 3.387 ± 1.022
5.579ValLys: 5.579 ± 2.75
4.981ValLeu: 4.981 ± 0.542
1.395ValMet: 1.395 ± 0.521
1.793ValAsn: 1.793 ± 0.33
2.59ValPro: 2.59 ± 1.154
0.598ValGln: 0.598 ± 0.19
2.59ValArg: 2.59 ± 0.813
6.376ValSer: 6.376 ± 1.188
2.391ValThr: 2.391 ± 0.965
2.59ValVal: 2.59 ± 1.305
0.199ValTrp: 0.199 ± 0.116
2.391ValTyr: 2.391 ± 0.47
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.199TrpAsp: 0.199 ± 0.236
0.598TrpGlu: 0.598 ± 0.352
0.398TrpPhe: 0.398 ± 0.18
0.199TrpGly: 0.199 ± 0.236
0.0TrpHis: 0.0 ± 0.0
0.598TrpIle: 0.598 ± 0.707
0.996TrpLys: 0.996 ± 0.262
0.797TrpLeu: 0.797 ± 0.259
0.398TrpMet: 0.398 ± 0.233
0.398TrpAsn: 0.398 ± 0.289
0.199TrpPro: 0.199 ± 0.236
0.0TrpGln: 0.0 ± 0.0
0.398TrpArg: 0.398 ± 0.406
1.195TrpSer: 1.195 ± 0.306
0.598TrpThr: 0.598 ± 0.296
0.398TrpVal: 0.398 ± 0.642
0.199TrpTrp: 0.199 ± 0.236
0.398TrpTyr: 0.398 ± 0.406
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.395TyrAla: 1.395 ± 0.521
0.996TyrCys: 0.996 ± 0.351
2.989TyrAsp: 2.989 ± 0.455
1.594TyrGlu: 1.594 ± 0.269
1.793TyrPhe: 1.793 ± 0.473
2.59TyrGly: 2.59 ± 1.203
0.797TyrHis: 0.797 ± 0.389
3.188TyrIle: 3.188 ± 0.815
4.383TyrLys: 4.383 ± 1.475
3.786TyrLeu: 3.786 ± 0.844
1.594TyrMet: 1.594 ± 0.578
1.992TyrAsn: 1.992 ± 0.461
0.598TyrPro: 0.598 ± 0.19
1.992TyrGln: 1.992 ± 0.845
1.395TyrArg: 1.395 ± 0.223
3.188TyrSer: 3.188 ± 0.413
1.793TyrThr: 1.793 ± 0.57
2.192TyrVal: 2.192 ± 0.394
0.199TyrTrp: 0.199 ± 0.389
1.992TyrTyr: 1.992 ± 0.652
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (5020 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski