Amino acid dipepetide frequency for Paenibacillus ginsengarvi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.468AlaAla: 10.468 ± 0.108	0.798AlaCys: 0.798 ± 0.02	5.079AlaAsp: 5.079 ± 0.052	6.321AlaGlu: 6.321 ± 0.071	3.572AlaPhe: 3.572 ± 0.037	7.86AlaGly: 7.86 ± 0.082	1.437AlaHis: 1.437 ± 0.027	5.463AlaIle: 5.463 ± 0.053	4.635AlaLys: 4.635 ± 0.05	8.378AlaLeu: 8.378 ± 0.071	2.402AlaMet: 2.402 ± 0.032	2.806AlaAsn: 2.806 ± 0.039	3.204AlaPro: 3.204 ± 0.043	2.633AlaGln: 2.633 ± 0.039	4.051AlaArg: 4.051 ± 0.045	5.506AlaSer: 5.506 ± 0.054	3.77AlaThr: 3.77 ± 0.05	6.837AlaVal: 6.837 ± 0.07	0.937AlaTrp: 0.937 ± 0.021	3.048AlaTyr: 3.048 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.631CysAla: 0.631 ± 0.017	0.137CysCys: 0.137 ± 0.009	0.462CysAsp: 0.462 ± 0.016	0.518CysGlu: 0.518 ± 0.016	0.322CysPhe: 0.322 ± 0.012	0.902CysGly: 0.902 ± 0.02	0.213CysHis: 0.213 ± 0.008	0.49CysIle: 0.49 ± 0.015	0.35CysLys: 0.35 ± 0.013	0.775CysLeu: 0.775 ± 0.02	0.213CysMet: 0.213 ± 0.009	0.269CysAsn: 0.269 ± 0.01	0.371CysPro: 0.371 ± 0.015	0.194CysGln: 0.194 ± 0.009	0.57CysArg: 0.57 ± 0.016	0.61CysSer: 0.61 ± 0.016	0.44CysThr: 0.44 ± 0.015	0.504CysVal: 0.504 ± 0.017	0.106CysTrp: 0.106 ± 0.007	0.321CysTyr: 0.321 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	4.139AspAla: 4.139 ± 0.048	0.491AspCys: 0.491 ± 0.015	2.585AspAsp: 2.585 ± 0.037	3.728AspGlu: 3.728 ± 0.043	2.039AspPhe: 2.039 ± 0.033	4.66AspGly: 4.66 ± 0.056	1.044AspHis: 1.044 ± 0.024	3.553AspIle: 3.553 ± 0.041	2.755AspLys: 2.755 ± 0.035	4.726AspLeu: 4.726 ± 0.054	1.495AspMet: 1.495 ± 0.023	1.746AspAsn: 1.746 ± 0.033	2.664AspPro: 2.664 ± 0.037	1.575AspGln: 1.575 ± 0.025	3.307AspArg: 3.307 ± 0.035	2.95AspSer: 2.95 ± 0.039	2.601AspThr: 2.601 ± 0.034	3.731AspVal: 3.731 ± 0.047	0.906AspTrp: 0.906 ± 0.022	2.106AspTyr: 2.106 ± 0.029	0.0AspXaa: 0.0 ± 0.0
Glu	6.457GluAla: 6.457 ± 0.066	0.444GluCys: 0.444 ± 0.014	2.667GluAsp: 2.667 ± 0.037	4.645GluGlu: 4.645 ± 0.068	1.977GluPhe: 1.977 ± 0.03	4.353GluGly: 4.353 ± 0.047	1.47GluHis: 1.47 ± 0.03	3.401GluIle: 3.401 ± 0.045	3.539GluLys: 3.539 ± 0.044	7.274GluLeu: 7.274 ± 0.063	1.856GluMet: 1.856 ± 0.029	1.982GluAsn: 1.982 ± 0.029	2.767GluPro: 2.767 ± 0.038	3.545GluGln: 3.545 ± 0.045	4.663GluArg: 4.663 ± 0.058	3.484GluSer: 3.484 ± 0.044	3.709GluThr: 3.709 ± 0.04	3.864GluVal: 3.864 ± 0.042	0.982GluTrp: 0.982 ± 0.021	1.9GluTyr: 1.9 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.715PheAla: 3.715 ± 0.043	0.397PheCys: 0.397 ± 0.014	2.498PheAsp: 2.498 ± 0.039	2.446PheGlu: 2.446 ± 0.032	1.584PhePhe: 1.584 ± 0.031	3.491PheGly: 3.491 ± 0.041	0.988PheHis: 0.988 ± 0.022	2.361PheIle: 2.361 ± 0.035	1.807PheLys: 1.807 ± 0.028	3.641PheLeu: 3.641 ± 0.053	0.989PheMet: 0.989 ± 0.022	1.325PheAsn: 1.325 ± 0.027	1.721PhePro: 1.721 ± 0.025	1.373PheGln: 1.373 ± 0.024	2.422PheArg: 2.422 ± 0.034	2.519PheSer: 2.519 ± 0.033	2.262PheThr: 2.262 ± 0.031	3.085PheVal: 3.085 ± 0.039	0.518PheTrp: 0.518 ± 0.018	1.563PheTyr: 1.563 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	6.374GlyAla: 6.374 ± 0.071	0.853GlyCys: 0.853 ± 0.019	3.879GlyAsp: 3.879 ± 0.046	4.848GlyGlu: 4.848 ± 0.043	3.242GlyPhe: 3.242 ± 0.045	6.505GlyGly: 6.505 ± 0.073	1.582GlyHis: 1.582 ± 0.026	5.232GlyIle: 5.232 ± 0.056	4.793GlyLys: 4.793 ± 0.053	7.326GlyLeu: 7.326 ± 0.057	2.335GlyMet: 2.335 ± 0.031	2.848GlyAsn: 2.848 ± 0.042	2.228GlyPro: 2.228 ± 0.034	2.775GlyGln: 2.775 ± 0.036	4.078GlyArg: 4.078 ± 0.053	5.201GlySer: 5.201 ± 0.062	4.978GlyThr: 4.978 ± 0.064	5.363GlyVal: 5.363 ± 0.047	1.235GlyTrp: 1.235 ± 0.025	3.07GlyTyr: 3.07 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	1.521HisAla: 1.521 ± 0.029	0.21HisCys: 0.21 ± 0.009	1.027HisAsp: 1.027 ± 0.023	1.181HisGlu: 1.181 ± 0.023	1.006HisPhe: 1.006 ± 0.022	1.495HisGly: 1.495 ± 0.026	0.576HisHis: 0.576 ± 0.017	1.402HisIle: 1.402 ± 0.026	0.815HisLys: 0.815 ± 0.016	2.071HisLeu: 2.071 ± 0.034	0.6HisMet: 0.6 ± 0.02	0.645HisAsn: 0.645 ± 0.018	1.223HisPro: 1.223 ± 0.022	0.665HisGln: 0.665 ± 0.018	1.24HisArg: 1.24 ± 0.026	1.173HisSer: 1.173 ± 0.022	1.121HisThr: 1.121 ± 0.024	1.403HisVal: 1.403 ± 0.028	0.309HisTrp: 0.309 ± 0.01	0.914HisTyr: 0.914 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.155IleAla: 6.155 ± 0.052	0.519IleCys: 0.519 ± 0.016	3.608IleAsp: 3.608 ± 0.041	4.026IleGlu: 4.026 ± 0.041	1.909IlePhe: 1.909 ± 0.031	5.344IleGly: 5.344 ± 0.048	1.299IleHis: 1.299 ± 0.026	2.912IleIle: 2.912 ± 0.048	2.383IleLys: 2.383 ± 0.034	4.311IleLeu: 4.311 ± 0.05	1.343IleMet: 1.343 ± 0.024	1.892IleAsn: 1.892 ± 0.031	3.008IlePro: 3.008 ± 0.043	2.036IleGln: 2.036 ± 0.03	4.366IleArg: 4.366 ± 0.049	3.634IleSer: 3.634 ± 0.044	3.342IleThr: 3.342 ± 0.043	5.244IleVal: 5.244 ± 0.059	0.715IleTrp: 0.715 ± 0.017	1.743IleTyr: 1.743 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.336LysAla: 4.336 ± 0.052	0.219LysCys: 0.219 ± 0.01	2.692LysAsp: 2.692 ± 0.042	3.747LysGlu: 3.747 ± 0.045	1.593LysPhe: 1.593 ± 0.033	3.405LysGly: 3.405 ± 0.038	1.07LysHis: 1.07 ± 0.026	2.518LysIle: 2.518 ± 0.037	2.87LysLys: 2.87 ± 0.05	5.441LysLeu: 5.441 ± 0.053	1.585LysMet: 1.585 ± 0.026	1.772LysAsn: 1.772 ± 0.029	2.616LysPro: 2.616 ± 0.034	2.367LysGln: 2.367 ± 0.033	3.128LysArg: 3.128 ± 0.043	2.805LysSer: 2.805 ± 0.035	2.931LysThr: 2.931 ± 0.038	3.132LysVal: 3.132 ± 0.039	0.72LysTrp: 0.72 ± 0.02	1.667LysTyr: 1.667 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	8.84LeuAla: 8.84 ± 0.074	0.876LeuCys: 0.876 ± 0.02	5.162LeuAsp: 5.162 ± 0.058	5.962LeuGlu: 5.962 ± 0.068	4.606LeuPhe: 4.606 ± 0.06	6.676LeuGly: 6.676 ± 0.058	2.184LeuHis: 2.184 ± 0.028	5.439LeuIle: 5.439 ± 0.058	4.643LeuLys: 4.643 ± 0.05	10.968LeuLeu: 10.968 ± 0.094	2.256LeuMet: 2.256 ± 0.031	3.496LeuAsn: 3.496 ± 0.043	4.693LeuPro: 4.693 ± 0.051	3.668LeuGln: 3.668 ± 0.045	5.566LeuArg: 5.566 ± 0.051	6.671LeuSer: 6.671 ± 0.063	5.497LeuThr: 5.497 ± 0.051	6.292LeuVal: 6.292 ± 0.065	1.067LeuTrp: 1.067 ± 0.022	3.449LeuTyr: 3.449 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.231MetAla: 2.231 ± 0.032	0.151MetCys: 0.151 ± 0.008	1.378MetAsp: 1.378 ± 0.025	1.786MetGlu: 1.786 ± 0.028	1.034MetPhe: 1.034 ± 0.018	1.546MetGly: 1.546 ± 0.025	0.473MetHis: 0.473 ± 0.014	1.679MetIle: 1.679 ± 0.028	1.821MetLys: 1.821 ± 0.029	2.83MetLeu: 2.83 ± 0.035	0.798MetMet: 0.798 ± 0.018	1.411MetAsn: 1.411 ± 0.027	1.178MetPro: 1.178 ± 0.023	1.043MetGln: 1.043 ± 0.022	1.491MetArg: 1.491 ± 0.025	1.745MetSer: 1.745 ± 0.023	1.803MetThr: 1.803 ± 0.03	1.433MetVal: 1.433 ± 0.026	0.26MetTrp: 0.26 ± 0.011	0.825MetTyr: 0.825 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.829AsnAla: 2.829 ± 0.037	0.315AsnCys: 0.315 ± 0.011	1.757AsnAsp: 1.757 ± 0.028	2.275AsnGlu: 2.275 ± 0.031	1.115AsnPhe: 1.115 ± 0.022	3.422AsnGly: 3.422 ± 0.051	0.658AsnHis: 0.658 ± 0.019	1.984AsnIle: 1.984 ± 0.031	1.986AsnLys: 1.986 ± 0.035	2.803AsnLeu: 2.803 ± 0.042	0.985AsnMet: 0.985 ± 0.021	1.358AsnAsn: 1.358 ± 0.033	1.984AsnPro: 1.984 ± 0.028	1.193AsnGln: 1.193 ± 0.026	2.318AsnArg: 2.318 ± 0.03	1.894AsnSer: 1.894 ± 0.03	1.913AsnThr: 1.913 ± 0.036	2.715AsnVal: 2.715 ± 0.045	0.601AsnTrp: 0.601 ± 0.018	1.196AsnTyr: 1.196 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	3.989ProAla: 3.989 ± 0.054	0.27ProCys: 0.27 ± 0.012	3.096ProAsp: 3.096 ± 0.038	3.447ProGlu: 3.447 ± 0.042	2.042ProPhe: 2.042 ± 0.029	3.739ProGly: 3.739 ± 0.047	0.988ProHis: 0.988 ± 0.018	2.489ProIle: 2.489 ± 0.031	1.901ProLys: 1.901 ± 0.03	4.189ProLeu: 4.189 ± 0.047	0.941ProMet: 0.941 ± 0.019	1.737ProAsn: 1.737 ± 0.032	1.604ProPro: 1.604 ± 0.027	1.436ProGln: 1.436 ± 0.027	1.606ProArg: 1.606 ± 0.025	2.709ProSer: 2.709 ± 0.037	2.004ProThr: 2.004 ± 0.03	3.626ProVal: 3.626 ± 0.038	0.525ProTrp: 0.525 ± 0.015	1.781ProTyr: 1.781 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.479GlnAla: 3.479 ± 0.049	0.196GlnCys: 0.196 ± 0.011	1.477GlnAsp: 1.477 ± 0.024	2.117GlnGlu: 2.117 ± 0.037	1.513GlnPhe: 1.513 ± 0.026	2.344GlnGly: 2.344 ± 0.038	0.738GlnHis: 0.738 ± 0.019	2.191GlnIle: 2.191 ± 0.033	1.701GlnLys: 1.701 ± 0.031	3.997GlnLeu: 3.997 ± 0.046	1.06GlnMet: 1.06 ± 0.022	1.26GlnAsn: 1.26 ± 0.023	1.659GlnPro: 1.659 ± 0.029	1.601GlnGln: 1.601 ± 0.033	1.84GlnArg: 1.84 ± 0.03	2.188GlnSer: 2.188 ± 0.033	2.246GlnThr: 2.246 ± 0.033	2.313GlnVal: 2.313 ± 0.033	0.478GlnTrp: 0.478 ± 0.015	1.31GlnTyr: 1.31 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	3.948ArgAla: 3.948 ± 0.048	0.486ArgCys: 0.486 ± 0.017	2.825ArgAsp: 2.825 ± 0.036	4.11ArgGlu: 4.11 ± 0.052	2.763ArgPhe: 2.763 ± 0.036	3.449ArgGly: 3.449 ± 0.041	1.31ArgHis: 1.31 ± 0.025	4.003ArgIle: 4.003 ± 0.042	3.187ArgLys: 3.187 ± 0.038	6.519ArgLeu: 6.519 ± 0.066	1.832ArgMet: 1.832 ± 0.025	2.055ArgAsn: 2.055 ± 0.032	2.078ArgPro: 2.078 ± 0.035	2.301ArgGln: 2.301 ± 0.034	3.346ArgArg: 3.346 ± 0.05	3.753ArgSer: 3.753 ± 0.038	3.186ArgThr: 3.186 ± 0.04	3.382ArgVal: 3.382 ± 0.045	0.809ArgTrp: 0.809 ± 0.018	2.134ArgTyr: 2.134 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.295SerAla: 5.295 ± 0.059	0.494SerCys: 0.494 ± 0.015	3.158SerAsp: 3.158 ± 0.035	3.623SerGlu: 3.623 ± 0.037	2.977SerPhe: 2.977 ± 0.037	6.213SerGly: 6.213 ± 0.065	1.195SerHis: 1.195 ± 0.022	3.845SerIle: 3.845 ± 0.053	2.856SerLys: 2.856 ± 0.039	6.08SerLeu: 6.08 ± 0.052	1.634SerMet: 1.634 ± 0.027	1.975SerAsn: 1.975 ± 0.031	2.794SerPro: 2.794 ± 0.043	1.779SerGln: 1.779 ± 0.026	3.59SerArg: 3.59 ± 0.036	3.959SerSer: 3.959 ± 0.052	2.826SerThr: 2.826 ± 0.035	4.672SerVal: 4.672 ± 0.06	0.804SerTrp: 0.804 ± 0.017	2.212SerTyr: 2.212 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.107ThrAla: 5.107 ± 0.06	0.393ThrCys: 0.393 ± 0.013	3.043ThrAsp: 3.043 ± 0.041	3.222ThrGlu: 3.222 ± 0.037	2.449ThrPhe: 2.449 ± 0.035	4.866ThrGly: 4.866 ± 0.071	0.973ThrHis: 0.973 ± 0.02	3.843ThrIle: 3.843 ± 0.042	2.425ThrLys: 2.425 ± 0.031	5.237ThrLeu: 5.237 ± 0.048	1.376ThrMet: 1.376 ± 0.022	1.981ThrAsn: 1.981 ± 0.033	2.661ThrPro: 2.661 ± 0.034	1.398ThrGln: 1.398 ± 0.026	2.427ThrArg: 2.427 ± 0.03	3.264ThrSer: 3.264 ± 0.038	2.767ThrThr: 2.767 ± 0.039	4.725ThrVal: 4.725 ± 0.058	0.716ThrTrp: 0.716 ± 0.019	1.973ThrTyr: 1.973 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	5.721ValAla: 5.721 ± 0.05	0.72ValCys: 0.72 ± 0.019	3.496ValAsp: 3.496 ± 0.043	3.929ValGlu: 3.929 ± 0.047	2.845ValPhe: 2.845 ± 0.038	4.583ValGly: 4.583 ± 0.056	1.464ValHis: 1.464 ± 0.027	4.22ValIle: 4.22 ± 0.037	3.677ValLys: 3.677 ± 0.036	6.96ValLeu: 6.96 ± 0.07	1.792ValMet: 1.792 ± 0.027	2.597ValAsn: 2.597 ± 0.037	3.428ValPro: 3.428 ± 0.04	2.715ValGln: 2.715 ± 0.036	4.328ValArg: 4.328 ± 0.049	4.94ValSer: 4.94 ± 0.056	4.672ValThr: 4.672 ± 0.065	5.001ValVal: 5.001 ± 0.054	0.929ValTrp: 0.929 ± 0.02	2.639ValTyr: 2.639 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.901TrpAla: 0.901 ± 0.019	0.103TrpCys: 0.103 ± 0.006	0.809TrpAsp: 0.809 ± 0.017	0.77TrpGlu: 0.77 ± 0.02	0.563TrpPhe: 0.563 ± 0.016	0.861TrpGly: 0.861 ± 0.021	0.303TrpHis: 0.303 ± 0.01	0.87TrpIle: 0.87 ± 0.02	0.799TrpLys: 0.799 ± 0.016	1.392TrpLeu: 1.392 ± 0.029	0.43TrpMet: 0.43 ± 0.012	0.71TrpAsn: 0.71 ± 0.019	0.422TrpPro: 0.422 ± 0.013	0.472TrpGln: 0.472 ± 0.014	0.738TrpArg: 0.738 ± 0.019	0.923TrpSer: 0.923 ± 0.023	0.809TrpThr: 0.809 ± 0.02	0.793TrpVal: 0.793 ± 0.02	0.176TrpTrp: 0.176 ± 0.009	0.483TrpTyr: 0.483 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.07TyrAla: 3.07 ± 0.037	0.328TyrCys: 0.328 ± 0.01	2.102TyrAsp: 2.102 ± 0.034	2.281TyrGlu: 2.281 ± 0.035	1.553TyrPhe: 1.553 ± 0.029	3.031TyrGly: 3.031 ± 0.037	0.63TyrHis: 0.63 ± 0.018	1.895TyrIle: 1.895 ± 0.028	1.671TyrLys: 1.671 ± 0.028	3.092TyrLeu: 3.092 ± 0.042	0.993TyrMet: 0.993 ± 0.021	1.433TyrAsn: 1.433 ± 0.027	1.813TyrPro: 1.813 ± 0.031	0.941TyrGln: 0.941 ± 0.021	2.399TyrArg: 2.399 ± 0.035	2.05TyrSer: 2.05 ± 0.028	1.971TyrThr: 1.971 ± 0.035	2.545TyrVal: 2.545 ± 0.031	0.534TyrTrp: 0.534 ± 0.014	1.475TyrTyr: 1.475 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.001

Statistics based on 6998 proteins (2380545 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---