Amino acid dipepetide frequency for Capybara microvirus Cap1_SP_216

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.712AlaAla: 0.712 ± 0.794
2.135AlaCys: 2.135 ± 1.306
4.27AlaAsp: 4.27 ± 1.5
4.27AlaGlu: 4.27 ± 1.212
2.135AlaPhe: 2.135 ± 1.452
4.27AlaGly: 4.27 ± 2.904
0.712AlaHis: 0.712 ± 0.794
3.559AlaIle: 3.559 ± 1.477
2.847AlaLys: 2.847 ± 0.837
5.694AlaLeu: 5.694 ± 2.067
0.712AlaMet: 0.712 ± 1.176
5.694AlaAsn: 5.694 ± 3.659
2.135AlaPro: 2.135 ± 1.384
2.847AlaGln: 2.847 ± 2.224
2.847AlaArg: 2.847 ± 1.115
2.135AlaSer: 2.135 ± 1.919
4.982AlaThr: 4.982 ± 2.794
5.694AlaVal: 5.694 ± 2.079
0.712AlaTrp: 0.712 ± 0.461
2.847AlaTyr: 2.847 ± 1.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.423CysAsp: 1.423 ± 0.923
0.0CysGlu: 0.0 ± 0.0
1.423CysPhe: 1.423 ± 1.278
2.135CysGly: 2.135 ± 1.552
0.0CysHis: 0.0 ± 0.0
0.712CysIle: 0.712 ± 1.176
2.847CysLys: 2.847 ± 1.341
0.712CysLeu: 0.712 ± 0.639
1.423CysMet: 1.423 ± 0.714
0.712CysAsn: 0.712 ± 1.176
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.712CysArg: 0.712 ± 0.639
0.712CysSer: 0.712 ± 0.639
0.0CysThr: 0.0 ± 0.0
0.712CysVal: 0.712 ± 1.176
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.135AspAla: 2.135 ± 0.926
0.712AspCys: 0.712 ± 0.639
4.982AspAsp: 4.982 ± 2.866
6.406AspGlu: 6.406 ± 1.47
4.982AspPhe: 4.982 ± 1.855
1.423AspGly: 1.423 ± 1.247
0.712AspHis: 0.712 ± 0.461
1.423AspIle: 1.423 ± 1.028
3.559AspLys: 3.559 ± 3.229
9.253AspLeu: 9.253 ± 2.103
1.423AspMet: 1.423 ± 0.858
4.27AspAsn: 4.27 ± 0.867
2.135AspPro: 2.135 ± 1.917
1.423AspGln: 1.423 ± 0.923
2.847AspArg: 2.847 ± 0.931
1.423AspSer: 1.423 ± 0.919
3.559AspThr: 3.559 ± 1.231
6.406AspVal: 6.406 ± 1.586
0.712AspTrp: 0.712 ± 1.176
4.982AspTyr: 4.982 ± 0.792
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
5.694GluAsp: 5.694 ± 1.459
2.847GluGlu: 2.847 ± 1.101
3.559GluPhe: 3.559 ± 1.139
1.423GluGly: 1.423 ± 0.729
0.712GluHis: 0.712 ± 0.639
2.847GluIle: 2.847 ± 0.989
9.253GluLys: 9.253 ± 3.139
5.694GluLeu: 5.694 ± 3.268
2.847GluMet: 2.847 ± 1.322
6.406GluAsn: 6.406 ± 2.972
2.135GluPro: 2.135 ± 1.676
3.559GluGln: 3.559 ± 1.507
3.559GluArg: 3.559 ± 0.976
2.135GluSer: 2.135 ± 1.698
3.559GluThr: 3.559 ± 1.217
4.982GluVal: 4.982 ± 2.395
1.423GluTrp: 1.423 ± 0.714
3.559GluTyr: 3.559 ± 1.286
0.0GluXaa: 0.0 ± 0.0
Phe
3.559PheAla: 3.559 ± 1.139
0.712PheCys: 0.712 ± 0.639
2.847PheAsp: 2.847 ± 1.846
4.982PheGlu: 4.982 ± 2.384
3.559PhePhe: 3.559 ± 2.131
3.559PheGly: 3.559 ± 1.205
1.423PheHis: 1.423 ± 0.714
3.559PheIle: 3.559 ± 1.963
2.135PheLys: 2.135 ± 1.602
2.135PheLeu: 2.135 ± 1.018
2.135PheMet: 2.135 ± 1.321
3.559PheAsn: 3.559 ± 1.696
2.135PhePro: 2.135 ± 1.076
1.423PheGln: 1.423 ± 0.923
1.423PheArg: 1.423 ± 0.843
3.559PheSer: 3.559 ± 1.583
2.847PheThr: 2.847 ± 0.973
2.847PheVal: 2.847 ± 1.283
2.135PheTrp: 2.135 ± 1.018
2.847PheTyr: 2.847 ± 1.671
0.0PheXaa: 0.0 ± 0.0
Gly
1.423GlyAla: 1.423 ± 0.923
2.135GlyCys: 2.135 ± 1.018
4.982GlyAsp: 4.982 ± 1.709
4.27GlyGlu: 4.27 ± 1.35
4.982GlyPhe: 4.982 ± 1.478
2.135GlyGly: 2.135 ± 1.384
1.423GlyHis: 1.423 ± 1.028
4.982GlyIle: 4.982 ± 1.248
2.847GlyLys: 2.847 ± 1.269
12.1GlyLeu: 12.1 ± 2.793
1.423GlyMet: 1.423 ± 0.729
4.27GlyAsn: 4.27 ± 1.462
0.712GlyPro: 0.712 ± 0.461
0.712GlyGln: 0.712 ± 0.461
1.423GlyArg: 1.423 ± 0.714
4.982GlySer: 4.982 ± 1.848
4.27GlyThr: 4.27 ± 1.398
4.27GlyVal: 4.27 ± 1.006
0.712GlyTrp: 0.712 ± 0.461
2.847GlyTyr: 2.847 ± 1.884
0.0GlyXaa: 0.0 ± 0.0
His
1.423HisAla: 1.423 ± 1.247
0.0HisCys: 0.0 ± 0.0
2.135HisAsp: 2.135 ± 2.309
0.712HisGlu: 0.712 ± 0.639
1.423HisPhe: 1.423 ± 1.028
2.135HisGly: 2.135 ± 0.926
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.135HisLys: 2.135 ± 0.802
2.847HisLeu: 2.847 ± 1.427
1.423HisMet: 1.423 ± 1.39
2.847HisAsn: 2.847 ± 0.989
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.712HisSer: 0.712 ± 0.461
2.847HisThr: 2.847 ± 1.41
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.712HisTyr: 0.712 ± 0.639
0.0HisXaa: 0.0 ± 0.0
Ile
4.982IleAla: 4.982 ± 3.739
0.712IleCys: 0.712 ± 1.176
3.559IleAsp: 3.559 ± 1.467
1.423IleGlu: 1.423 ± 1.622
3.559IlePhe: 3.559 ± 1.206
4.982IleGly: 4.982 ± 1.992
1.423IleHis: 1.423 ± 2.351
1.423IleIle: 1.423 ± 1.22
6.406IleLys: 6.406 ± 3.654
3.559IleLeu: 3.559 ± 2.1
1.423IleMet: 1.423 ± 0.923
2.847IleAsn: 2.847 ± 0.837
2.847IlePro: 2.847 ± 0.973
2.847IleGln: 2.847 ± 0.837
2.135IleArg: 2.135 ± 1.676
2.847IleSer: 2.847 ± 1.339
2.135IleThr: 2.135 ± 1.018
2.135IleVal: 2.135 ± 1.128
1.423IleTrp: 1.423 ± 0.729
4.27IleTyr: 4.27 ± 1.517
0.0IleXaa: 0.0 ± 0.0
Lys
4.982LysAla: 4.982 ± 2.693
0.712LysCys: 0.712 ± 1.176
2.847LysAsp: 2.847 ± 1.427
4.27LysGlu: 4.27 ± 2.386
0.712LysPhe: 0.712 ± 0.461
4.27LysGly: 4.27 ± 2.873
2.135LysHis: 2.135 ± 1.384
5.694LysIle: 5.694 ± 3.11
3.559LysLys: 3.559 ± 1.189
7.829LysLeu: 7.829 ± 0.787
2.847LysMet: 2.847 ± 1.414
4.27LysAsn: 4.27 ± 2.513
0.712LysPro: 0.712 ± 0.461
2.135LysGln: 2.135 ± 1.257
3.559LysArg: 3.559 ± 1.662
1.423LysSer: 1.423 ± 1.165
1.423LysThr: 1.423 ± 1.39
5.694LysVal: 5.694 ± 1.084
0.712LysTrp: 0.712 ± 0.461
3.559LysTyr: 3.559 ± 1.916
0.0LysXaa: 0.0 ± 0.0
Leu
6.406LeuAla: 6.406 ± 1.859
1.423LeuCys: 1.423 ± 2.351
4.982LeuAsp: 4.982 ± 2.414
6.406LeuGlu: 6.406 ± 2.819
4.27LeuPhe: 4.27 ± 1.552
5.694LeuGly: 5.694 ± 2.096
2.135LeuHis: 2.135 ± 1.54
4.982LeuIle: 4.982 ± 1.429
4.982LeuLys: 4.982 ± 2.549
2.847LeuLeu: 2.847 ± 1.884
0.712LeuMet: 0.712 ± 0.639
9.964LeuAsn: 9.964 ± 3.024
4.982LeuPro: 4.982 ± 2.72
4.982LeuGln: 4.982 ± 1.956
4.27LeuArg: 4.27 ± 2.141
7.829LeuSer: 7.829 ± 2.536
3.559LeuThr: 3.559 ± 1.231
4.982LeuVal: 4.982 ± 2.403
0.0LeuTrp: 0.0 ± 0.0
0.712LeuTyr: 0.712 ± 1.176
0.0LeuXaa: 0.0 ± 0.0
Met
2.847MetAla: 2.847 ± 1.121
0.712MetCys: 0.712 ± 0.461
1.423MetAsp: 1.423 ± 1.028
0.712MetGlu: 0.712 ± 0.639
1.423MetPhe: 1.423 ± 1.051
0.712MetGly: 0.712 ± 0.461
0.0MetHis: 0.0 ± 0.0
0.712MetIle: 0.712 ± 0.461
0.712MetLys: 0.712 ± 1.176
0.0MetLeu: 0.0 ± 0.0
0.712MetMet: 0.712 ± 0.461
2.847MetAsn: 2.847 ± 1.269
0.712MetPro: 0.712 ± 0.794
0.0MetGln: 0.0 ± 0.0
2.847MetArg: 2.847 ± 1.297
3.559MetSer: 3.559 ± 1.895
0.712MetThr: 0.712 ± 0.794
1.423MetVal: 1.423 ± 0.834
0.0MetTrp: 0.0 ± 0.0
2.135MetTyr: 2.135 ± 1.384
0.0MetXaa: 0.0 ± 0.0
Asn
5.694AsnAla: 5.694 ± 2.801
2.847AsnCys: 2.847 ± 1.364
3.559AsnAsp: 3.559 ± 1.318
5.694AsnGlu: 5.694 ± 1.345
7.829AsnPhe: 7.829 ± 0.787
5.694AsnGly: 5.694 ± 2.888
1.423AsnHis: 1.423 ± 0.729
3.559AsnIle: 3.559 ± 1.507
2.847AsnLys: 2.847 ± 2.61
5.694AsnLeu: 5.694 ± 3.594
0.712AsnMet: 0.712 ± 0.461
0.712AsnAsn: 0.712 ± 0.461
3.559AsnPro: 3.559 ± 1.73
1.423AsnGln: 1.423 ± 0.923
2.847AsnArg: 2.847 ± 0.931
4.982AsnSer: 4.982 ± 1.911
4.27AsnThr: 4.27 ± 1.517
4.27AsnVal: 4.27 ± 1.398
0.712AsnTrp: 0.712 ± 0.639
3.559AsnTyr: 3.559 ± 1.835
0.0AsnXaa: 0.0 ± 0.0
Pro
0.712ProAla: 0.712 ± 0.461
0.712ProCys: 0.712 ± 0.639
3.559ProAsp: 3.559 ± 1.72
2.135ProGlu: 2.135 ± 1.384
1.423ProPhe: 1.423 ± 0.919
1.423ProGly: 1.423 ± 0.923
2.135ProHis: 2.135 ± 1.274
2.847ProIle: 2.847 ± 1.341
2.135ProLys: 2.135 ± 0.926
4.982ProLeu: 4.982 ± 2.578
2.135ProMet: 2.135 ± 1.018
2.135ProAsn: 2.135 ± 1.274
1.423ProPro: 1.423 ± 0.834
0.712ProGln: 0.712 ± 0.461
2.847ProArg: 2.847 ± 0.837
0.712ProSer: 0.712 ± 0.639
1.423ProThr: 1.423 ± 0.729
0.712ProVal: 0.712 ± 0.461
0.712ProTrp: 0.712 ± 0.461
2.135ProTyr: 2.135 ± 1.415
0.0ProXaa: 0.0 ± 0.0
Gln
4.27GlnAla: 4.27 ± 4.022
0.712GlnCys: 0.712 ± 0.461
0.0GlnAsp: 0.0 ± 0.0
0.712GlnGlu: 0.712 ± 0.461
0.0GlnPhe: 0.0 ± 0.0
7.117GlnGly: 7.117 ± 2.161
0.712GlnHis: 0.712 ± 0.794
1.423GlnIle: 1.423 ± 0.729
4.982GlnLys: 4.982 ± 1.558
2.847GlnLeu: 2.847 ± 0.837
0.0GlnMet: 0.0 ± 0.0
2.135GlnAsn: 2.135 ± 0.977
0.712GlnPro: 0.712 ± 0.639
2.135GlnGln: 2.135 ± 1.452
2.135GlnArg: 2.135 ± 0.926
1.423GlnSer: 1.423 ± 0.923
2.847GlnThr: 2.847 ± 1.341
1.423GlnVal: 1.423 ± 0.923
0.712GlnTrp: 0.712 ± 0.461
0.712GlnTyr: 0.712 ± 0.461
0.0GlnXaa: 0.0 ± 0.0
Arg
1.423ArgAla: 1.423 ± 0.843
0.0ArgCys: 0.0 ± 0.0
2.135ArgAsp: 2.135 ± 1.384
5.694ArgGlu: 5.694 ± 1.524
4.982ArgPhe: 4.982 ± 2.665
2.135ArgGly: 2.135 ± 1.384
1.423ArgHis: 1.423 ± 0.923
2.847ArgIle: 2.847 ± 1.542
2.847ArgLys: 2.847 ± 1.41
4.27ArgLeu: 4.27 ± 2.291
0.0ArgMet: 0.0 ± 0.0
0.712ArgAsn: 0.712 ± 1.176
4.982ArgPro: 4.982 ± 1.733
1.423ArgGln: 1.423 ± 0.714
2.135ArgArg: 2.135 ± 1.257
2.847ArgSer: 2.847 ± 1.542
0.712ArgThr: 0.712 ± 0.639
1.423ArgVal: 1.423 ± 1.165
0.0ArgTrp: 0.0 ± 0.0
2.135ArgTyr: 2.135 ± 1.018
0.0ArgXaa: 0.0 ± 0.0
Ser
4.982SerAla: 4.982 ± 2.887
0.0SerCys: 0.0 ± 0.0
4.27SerAsp: 4.27 ± 1.991
2.135SerGlu: 2.135 ± 1.076
0.0SerPhe: 0.0 ± 0.0
6.406SerGly: 6.406 ± 3.536
1.423SerHis: 1.423 ± 0.919
6.406SerIle: 6.406 ± 3.833
4.27SerLys: 4.27 ± 0.91
4.982SerLeu: 4.982 ± 1.742
2.135SerMet: 2.135 ± 0.926
4.982SerAsn: 4.982 ± 2.18
3.559SerPro: 3.559 ± 1.963
5.694SerGln: 5.694 ± 3.116
2.135SerArg: 2.135 ± 1.274
8.541SerSer: 8.541 ± 1.988
2.135SerThr: 2.135 ± 1.018
2.135SerVal: 2.135 ± 0.977
0.0SerTrp: 0.0 ± 0.0
2.135SerTyr: 2.135 ± 1.388
0.0SerXaa: 0.0 ± 0.0
Thr
4.27ThrAla: 4.27 ± 2.003
0.0ThrCys: 0.0 ± 0.0
2.847ThrAsp: 2.847 ± 1.341
5.694ThrGlu: 5.694 ± 1.825
2.847ThrPhe: 2.847 ± 1.41
2.135ThrGly: 2.135 ± 0.697
0.0ThrHis: 0.0 ± 0.0
3.559ThrIle: 3.559 ± 1.867
0.712ThrLys: 0.712 ± 0.639
3.559ThrLeu: 3.559 ± 1.158
0.0ThrMet: 0.0 ± 0.0
4.982ThrAsn: 4.982 ± 2.109
1.423ThrPro: 1.423 ± 0.729
0.712ThrGln: 0.712 ± 0.794
2.135ThrArg: 2.135 ± 1.274
7.829ThrSer: 7.829 ± 2.504
1.423ThrThr: 1.423 ± 0.729
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
4.27ThrTyr: 4.27 ± 1.35
0.0ThrXaa: 0.0 ± 0.0
Val
7.117ValAla: 7.117 ± 3.576
0.0ValCys: 0.0 ± 0.0
4.982ValAsp: 4.982 ± 1.609
4.27ValGlu: 4.27 ± 2.505
1.423ValPhe: 1.423 ± 1.028
3.559ValGly: 3.559 ± 1.73
1.423ValHis: 1.423 ± 1.051
2.847ValIle: 2.847 ± 1.041
2.847ValLys: 2.847 ± 1.427
2.847ValLeu: 2.847 ± 1.751
1.423ValMet: 1.423 ± 0.729
2.135ValAsn: 2.135 ± 1.018
2.135ValPro: 2.135 ± 0.802
2.135ValGln: 2.135 ± 0.926
2.135ValArg: 2.135 ± 1.023
5.694ValSer: 5.694 ± 1.793
1.423ValThr: 1.423 ± 1.278
3.559ValVal: 3.559 ± 0.676
0.712ValTrp: 0.712 ± 1.166
2.847ValTyr: 2.847 ± 1.427
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.712TrpAsp: 0.712 ± 0.461
0.712TrpGlu: 0.712 ± 0.461
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.712TrpHis: 0.712 ± 0.461
0.712TrpIle: 0.712 ± 0.461
0.712TrpLys: 0.712 ± 0.639
1.423TrpLeu: 1.423 ± 1.028
0.0TrpMet: 0.0 ± 0.0
0.712TrpAsn: 0.712 ± 0.794
0.712TrpPro: 0.712 ± 0.461
0.0TrpGln: 0.0 ± 0.0
1.423TrpArg: 1.423 ± 0.714
2.135TrpSer: 2.135 ± 1.089
0.712TrpThr: 0.712 ± 0.461
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.712TrpTyr: 0.712 ± 0.461
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.27TyrAla: 4.27 ± 1.398
0.0TyrCys: 0.0 ± 0.0
3.559TyrAsp: 3.559 ± 1.951
2.847TyrGlu: 2.847 ± 1.341
2.847TyrPhe: 2.847 ± 1.115
5.694TyrGly: 5.694 ± 2.354
1.423TyrHis: 1.423 ± 1.278
2.847TyrIle: 2.847 ± 1.18
1.423TyrLys: 1.423 ± 0.729
2.847TyrLeu: 2.847 ± 1.283
0.0TyrMet: 0.0 ± 0.0
5.694TyrAsn: 5.694 ± 1.486
0.0TyrPro: 0.0 ± 0.0
2.847TyrGln: 2.847 ± 1.804
0.712TyrArg: 0.712 ± 0.461
2.847TyrSer: 2.847 ± 1.115
3.559TyrThr: 3.559 ± 0.789
2.847TyrVal: 2.847 ± 0.931
0.712TyrTrp: 0.712 ± 0.461
1.423TyrTyr: 1.423 ± 0.834
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1406 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski