Amino acid dipepetide frequency for Swingsia samuiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.442AlaAla: 9.442 ± 0.173
1.076AlaCys: 1.076 ± 0.037
4.648AlaAsp: 4.648 ± 0.09
5.428AlaGlu: 5.428 ± 0.104
3.535AlaPhe: 3.535 ± 0.08
7.497AlaGly: 7.497 ± 0.115
2.393AlaHis: 2.393 ± 0.058
5.588AlaIle: 5.588 ± 0.099
3.78AlaLys: 3.78 ± 0.079
11.268AlaLeu: 11.268 ± 0.164
2.388AlaMet: 2.388 ± 0.068
2.771AlaAsn: 2.771 ± 0.071
4.35AlaPro: 4.35 ± 0.093
4.356AlaGln: 4.356 ± 0.1
5.855AlaArg: 5.855 ± 0.114
6.109AlaSer: 6.109 ± 0.1
4.655AlaThr: 4.655 ± 0.093
6.089AlaVal: 6.089 ± 0.121
1.206AlaTrp: 1.206 ± 0.046
2.231AlaTyr: 2.231 ± 0.056
0.0AlaXaa: 0.0 ± 0.0
Cys
0.915CysAla: 0.915 ± 0.036
0.137CysCys: 0.137 ± 0.014
0.496CysAsp: 0.496 ± 0.031
0.377CysGlu: 0.377 ± 0.024
0.397CysPhe: 0.397 ± 0.025
0.843CysGly: 0.843 ± 0.035
0.282CysHis: 0.282 ± 0.024
0.574CysIle: 0.574 ± 0.031
0.226CysLys: 0.226 ± 0.018
0.869CysLeu: 0.869 ± 0.037
0.163CysMet: 0.163 ± 0.016
0.272CysAsn: 0.272 ± 0.021
0.429CysPro: 0.429 ± 0.029
0.29CysGln: 0.29 ± 0.022
0.508CysArg: 0.508 ± 0.026
0.672CysSer: 0.672 ± 0.03
0.405CysThr: 0.405 ± 0.025
0.661CysVal: 0.661 ± 0.032
0.128CysTrp: 0.128 ± 0.014
0.168CysTyr: 0.168 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
5.051AspAla: 5.051 ± 0.111
0.405AspCys: 0.405 ± 0.026
2.615AspAsp: 2.615 ± 0.074
3.225AspGlu: 3.225 ± 0.084
2.133AspPhe: 2.133 ± 0.065
4.165AspGly: 4.165 ± 0.088
1.405AspHis: 1.405 ± 0.043
3.733AspIle: 3.733 ± 0.084
1.988AspLys: 1.988 ± 0.056
5.631AspLeu: 5.631 ± 0.097
1.316AspMet: 1.316 ± 0.042
1.693AspAsn: 1.693 ± 0.056
2.935AspPro: 2.935 ± 0.074
2.09AspGln: 2.09 ± 0.057
3.272AspArg: 3.272 ± 0.071
2.29AspSer: 2.29 ± 0.064
2.66AspThr: 2.66 ± 0.078
3.892AspVal: 3.892 ± 0.078
0.812AspTrp: 0.812 ± 0.037
1.513AspTyr: 1.513 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
5.848GluAla: 5.848 ± 0.121
0.394GluCys: 0.394 ± 0.027
3.012GluAsp: 3.012 ± 0.074
3.878GluGlu: 3.878 ± 0.098
1.647GluPhe: 1.647 ± 0.049
3.903GluGly: 3.903 ± 0.072
1.428GluHis: 1.428 ± 0.047
3.609GluIle: 3.609 ± 0.07
3.62GluLys: 3.62 ± 0.096
5.061GluLeu: 5.061 ± 0.108
1.441GluMet: 1.441 ± 0.042
2.693GluAsn: 2.693 ± 0.071
1.989GluPro: 1.989 ± 0.058
2.524GluGln: 2.524 ± 0.063
4.19GluArg: 4.19 ± 0.098
2.637GluSer: 2.637 ± 0.068
3.356GluThr: 3.356 ± 0.074
3.538GluVal: 3.538 ± 0.074
0.826GluTrp: 0.826 ± 0.041
1.162GluTyr: 1.162 ± 0.044
0.0GluXaa: 0.0 ± 0.0
Phe
3.406PheAla: 3.406 ± 0.072
0.49PheCys: 0.49 ± 0.027
2.235PheAsp: 2.235 ± 0.062
1.933PheGlu: 1.933 ± 0.063
1.713PhePhe: 1.713 ± 0.058
3.162PheGly: 3.162 ± 0.074
0.896PheHis: 0.896 ± 0.034
2.318PheIle: 2.318 ± 0.074
1.392PheLys: 1.392 ± 0.048
4.04PheLeu: 4.04 ± 0.092
0.841PheMet: 0.841 ± 0.035
1.408PheAsn: 1.408 ± 0.052
1.747PhePro: 1.747 ± 0.058
1.334PheGln: 1.334 ± 0.05
1.876PheArg: 1.876 ± 0.055
3.356PheSer: 3.356 ± 0.076
1.964PheThr: 1.964 ± 0.053
2.501PheVal: 2.501 ± 0.066
0.545PheTrp: 0.545 ± 0.035
0.989PheTyr: 0.989 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
6.891GlyAla: 6.891 ± 0.125
0.782GlyCys: 0.782 ± 0.034
3.667GlyAsp: 3.667 ± 0.069
3.945GlyGlu: 3.945 ± 0.08
3.274GlyPhe: 3.274 ± 0.067
6.303GlyGly: 6.303 ± 0.147
2.09GlyHis: 2.09 ± 0.063
4.898GlyIle: 4.898 ± 0.108
3.689GlyLys: 3.689 ± 0.079
7.582GlyLeu: 7.582 ± 0.115
2.075GlyMet: 2.075 ± 0.064
2.585GlyAsn: 2.585 ± 0.08
2.695GlyPro: 2.695 ± 0.065
2.89GlyGln: 2.89 ± 0.069
4.71GlyArg: 4.71 ± 0.099
4.907GlySer: 4.907 ± 0.103
4.199GlyThr: 4.199 ± 0.091
5.727GlyVal: 5.727 ± 0.109
1.252GlyTrp: 1.252 ± 0.05
2.226GlyTyr: 2.226 ± 0.061
0.0GlyXaa: 0.0 ± 0.0
His
2.306HisAla: 2.306 ± 0.061
0.221HisCys: 0.221 ± 0.021
1.374HisAsp: 1.374 ± 0.04
1.312HisGlu: 1.312 ± 0.051
1.107HisPhe: 1.107 ± 0.041
1.982HisGly: 1.982 ± 0.06
0.905HisHis: 0.905 ± 0.04
1.759HisIle: 1.759 ± 0.054
1.018HisLys: 1.018 ± 0.041
2.568HisLeu: 2.568 ± 0.076
0.556HisMet: 0.556 ± 0.028
0.963HisAsn: 0.963 ± 0.04
1.51HisPro: 1.51 ± 0.052
0.879HisGln: 0.879 ± 0.032
1.347HisArg: 1.347 ± 0.053
1.602HisSer: 1.602 ± 0.056
1.313HisThr: 1.313 ± 0.046
1.725HisVal: 1.725 ± 0.05
0.4HisTrp: 0.4 ± 0.025
0.818HisTyr: 0.818 ± 0.046
0.0HisXaa: 0.0 ± 0.0
Ile
6.358IleAla: 6.358 ± 0.107
0.637IleCys: 0.637 ± 0.032
3.617IleAsp: 3.617 ± 0.083
3.689IleGlu: 3.689 ± 0.078
2.217IlePhe: 2.217 ± 0.065
4.945IleGly: 4.945 ± 0.105
1.382IleHis: 1.382 ± 0.047
4.072IleIle: 4.072 ± 0.095
2.522IleLys: 2.522 ± 0.07
6.176IleLeu: 6.176 ± 0.117
1.244IleMet: 1.244 ± 0.045
2.27IleAsn: 2.27 ± 0.074
3.431IlePro: 3.431 ± 0.065
2.197IleGln: 2.197 ± 0.062
3.512IleArg: 3.512 ± 0.063
4.744IleSer: 4.744 ± 0.099
3.75IleThr: 3.75 ± 0.075
4.147IleVal: 4.147 ± 0.083
0.701IleTrp: 0.701 ± 0.033
1.267IleTyr: 1.267 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
4.486LysAla: 4.486 ± 0.08
0.211LysCys: 0.211 ± 0.017
2.522LysAsp: 2.522 ± 0.07
3.032LysGlu: 3.032 ± 0.079
1.122LysPhe: 1.122 ± 0.042
3.11LysGly: 3.11 ± 0.065
1.012LysHis: 1.012 ± 0.04
2.983LysIle: 2.983 ± 0.07
2.78LysLys: 2.78 ± 0.091
3.965LysLeu: 3.965 ± 0.084
1.151LysMet: 1.151 ± 0.043
2.205LysAsn: 2.205 ± 0.063
2.151LysPro: 2.151 ± 0.065
1.692LysGln: 1.692 ± 0.053
2.855LysArg: 2.855 ± 0.065
2.629LysSer: 2.629 ± 0.064
2.874LysThr: 2.874 ± 0.077
2.641LysVal: 2.641 ± 0.063
0.463LysTrp: 0.463 ± 0.027
0.945LysTyr: 0.945 ± 0.045
0.0LysXaa: 0.0 ± 0.0
Leu
9.804LeuAla: 9.804 ± 0.157
0.985LeuCys: 0.985 ± 0.041
5.448LeuAsp: 5.448 ± 0.107
5.597LeuGlu: 5.597 ± 0.095
3.89LeuPhe: 3.89 ± 0.101
7.518LeuGly: 7.518 ± 0.136
2.574LeuHis: 2.574 ± 0.066
5.964LeuIle: 5.964 ± 0.115
5.129LeuLys: 5.129 ± 0.097
9.883LeuLeu: 9.883 ± 0.183
2.386LeuMet: 2.386 ± 0.072
3.805LeuAsn: 3.805 ± 0.075
5.987LeuPro: 5.987 ± 0.092
3.602LeuGln: 3.602 ± 0.081
6.2LeuArg: 6.2 ± 0.106
8.269LeuSer: 8.269 ± 0.13
5.915LeuThr: 5.915 ± 0.12
6.182LeuVal: 6.182 ± 0.105
1.215LeuTrp: 1.215 ± 0.052
2.444LeuTyr: 2.444 ± 0.068
0.0LeuXaa: 0.0 ± 0.0
Met
2.507MetAla: 2.507 ± 0.066
0.174MetCys: 0.174 ± 0.015
1.116MetAsp: 1.116 ± 0.041
1.086MetGlu: 1.086 ± 0.038
0.724MetPhe: 0.724 ± 0.031
1.785MetGly: 1.785 ± 0.052
0.515MetHis: 0.515 ± 0.03
1.481MetIle: 1.481 ± 0.053
1.167MetLys: 1.167 ± 0.037
2.331MetLeu: 2.331 ± 0.059
0.635MetMet: 0.635 ± 0.033
0.927MetAsn: 0.927 ± 0.039
1.379MetPro: 1.379 ± 0.044
0.904MetGln: 0.904 ± 0.038
1.48MetArg: 1.48 ± 0.045
1.904MetSer: 1.904 ± 0.054
1.628MetThr: 1.628 ± 0.047
1.414MetVal: 1.414 ± 0.043
0.18MetTrp: 0.18 ± 0.016
0.324MetTyr: 0.324 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.512AsnAla: 3.512 ± 0.081
0.282AsnCys: 0.282 ± 0.022
1.872AsnAsp: 1.872 ± 0.058
1.771AsnGlu: 1.771 ± 0.054
1.275AsnPhe: 1.275 ± 0.052
3.081AsnGly: 3.081 ± 0.099
0.902AsnHis: 0.902 ± 0.037
2.831AsnIle: 2.831 ± 0.078
1.516AsnLys: 1.516 ± 0.045
3.562AsnLeu: 3.562 ± 0.078
0.828AsnMet: 0.828 ± 0.034
1.754AsnAsn: 1.754 ± 0.074
2.167AsnPro: 2.167 ± 0.067
1.315AsnGln: 1.315 ± 0.055
1.977AsnArg: 1.977 ± 0.059
2.249AsnSer: 2.249 ± 0.087
2.186AsnThr: 2.186 ± 0.068
2.458AsnVal: 2.458 ± 0.07
0.542AsnTrp: 0.542 ± 0.024
0.994AsnTyr: 0.994 ± 0.051
0.0AsnXaa: 0.0 ± 0.0
Pro
4.126ProAla: 4.126 ± 0.088
0.302ProCys: 0.302 ± 0.021
3.263ProAsp: 3.263 ± 0.068
3.617ProGlu: 3.617 ± 0.08
2.122ProPhe: 2.122 ± 0.062
3.232ProGly: 3.232 ± 0.071
1.498ProHis: 1.498 ± 0.047
2.89ProIle: 2.89 ± 0.063
2.106ProLys: 2.106 ± 0.06
4.877ProLeu: 4.877 ± 0.102
1.025ProMet: 1.025 ± 0.038
1.912ProAsn: 1.912 ± 0.06
2.548ProPro: 2.548 ± 0.086
2.252ProGln: 2.252 ± 0.06
2.164ProArg: 2.164 ± 0.061
3.748ProSer: 3.748 ± 0.072
2.759ProThr: 2.759 ± 0.067
3.654ProVal: 3.654 ± 0.078
0.71ProTrp: 0.71 ± 0.035
1.365ProTyr: 1.365 ± 0.052
0.0ProXaa: 0.0 ± 0.0
Gln
4.08GlnAla: 4.08 ± 0.095
0.215GlnCys: 0.215 ± 0.016
1.878GlnAsp: 1.878 ± 0.054
2.359GlnGlu: 2.359 ± 0.069
1.26GlnPhe: 1.26 ± 0.044
2.677GlnGly: 2.677 ± 0.071
1.087GlnHis: 1.087 ± 0.039
2.565GlnIle: 2.565 ± 0.061
2.362GlnLys: 2.362 ± 0.074
3.22GlnLeu: 3.22 ± 0.079
0.968GlnMet: 0.968 ± 0.039
1.902GlnAsn: 1.902 ± 0.06
1.809GlnPro: 1.809 ± 0.057
1.654GlnGln: 1.654 ± 0.062
2.31GlnArg: 2.31 ± 0.066
2.599GlnSer: 2.599 ± 0.06
2.255GlnThr: 2.255 ± 0.061
2.299GlnVal: 2.299 ± 0.068
0.499GlnTrp: 0.499 ± 0.028
0.919GlnTyr: 0.919 ± 0.038
0.0GlnXaa: 0.0 ± 0.0
Arg
5.236ArgAla: 5.236 ± 0.111
0.426ArgCys: 0.426 ± 0.027
3.087ArgAsp: 3.087 ± 0.075
3.364ArgGlu: 3.364 ± 0.08
2.557ArgPhe: 2.557 ± 0.062
3.756ArgGly: 3.756 ± 0.08
1.545ArgHis: 1.545 ± 0.054
3.756ArgIle: 3.756 ± 0.076
2.678ArgLys: 2.678 ± 0.073
6.79ArgLeu: 6.79 ± 0.123
1.464ArgMet: 1.464 ± 0.05
2.061ArgAsn: 2.061 ± 0.06
2.761ArgPro: 2.761 ± 0.064
2.353ArgGln: 2.353 ± 0.063
3.953ArgArg: 3.953 ± 0.104
3.793ArgSer: 3.793 ± 0.083
2.803ArgThr: 2.803 ± 0.061
3.968ArgVal: 3.968 ± 0.097
0.753ArgTrp: 0.753 ± 0.039
1.687ArgTyr: 1.687 ± 0.053
0.0ArgXaa: 0.0 ± 0.0
Ser
5.947SerAla: 5.947 ± 0.101
0.553SerCys: 0.553 ± 0.031
3.599SerAsp: 3.599 ± 0.084
3.481SerGlu: 3.481 ± 0.072
2.983SerPhe: 2.983 ± 0.075
5.92SerGly: 5.92 ± 0.211
1.788SerHis: 1.788 ± 0.055
4.124SerIle: 4.124 ± 0.082
2.429SerLys: 2.429 ± 0.077
7.491SerLeu: 7.491 ± 0.122
1.466SerMet: 1.466 ± 0.047
2.312SerAsn: 2.312 ± 0.066
3.428SerPro: 3.428 ± 0.07
2.568SerGln: 2.568 ± 0.063
3.591SerArg: 3.591 ± 0.084
5.335SerSer: 5.335 ± 0.117
3.411SerThr: 3.411 ± 0.08
4.678SerVal: 4.678 ± 0.081
0.899SerTrp: 0.899 ± 0.037
1.713SerTyr: 1.713 ± 0.06
0.0SerXaa: 0.0 ± 0.0
Thr
5.116ThrAla: 5.116 ± 0.089
0.444ThrCys: 0.444 ± 0.031
2.706ThrAsp: 2.706 ± 0.061
2.712ThrGlu: 2.712 ± 0.067
2.054ThrPhe: 2.054 ± 0.054
4.57ThrGly: 4.57 ± 0.081
1.437ThrHis: 1.437 ± 0.045
3.512ThrIle: 3.512 ± 0.077
2.018ThrLys: 2.018 ± 0.054
6.542ThrLeu: 6.542 ± 0.109
1.115ThrMet: 1.115 ± 0.042
1.777ThrAsn: 1.777 ± 0.059
3.684ThrPro: 3.684 ± 0.081
2.089ThrGln: 2.089 ± 0.058
2.797ThrArg: 2.797 ± 0.067
3.678ThrSer: 3.678 ± 0.083
3.151ThrThr: 3.151 ± 0.066
3.863ThrVal: 3.863 ± 0.091
0.647ThrTrp: 0.647 ± 0.034
1.354ThrTyr: 1.354 ± 0.056
0.0ThrXaa: 0.0 ± 0.0
Val
6.41ValAla: 6.41 ± 0.113
0.696ValCys: 0.696 ± 0.033
3.51ValAsp: 3.51 ± 0.073
4.005ValGlu: 4.005 ± 0.093
2.591ValPhe: 2.591 ± 0.071
4.802ValGly: 4.802 ± 0.098
1.452ValHis: 1.452 ± 0.049
4.106ValIle: 4.106 ± 0.093
2.852ValLys: 2.852 ± 0.073
7.065ValLeu: 7.065 ± 0.116
1.754ValMet: 1.754 ± 0.057
2.22ValAsn: 2.22 ± 0.067
3.278ValPro: 3.278 ± 0.082
2.388ValGln: 2.388 ± 0.06
3.651ValArg: 3.651 ± 0.084
4.894ValSer: 4.894 ± 0.104
4.008ValThr: 4.008 ± 0.074
5.014ValVal: 5.014 ± 0.095
0.854ValTrp: 0.854 ± 0.037
1.385ValTyr: 1.385 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.991TrpAla: 0.991 ± 0.037
0.148TrpCys: 0.148 ± 0.015
0.608TrpAsp: 0.608 ± 0.037
0.617TrpGlu: 0.617 ± 0.035
0.531TrpPhe: 0.531 ± 0.032
0.918TrpGly: 0.918 ± 0.037
0.412TrpHis: 0.412 ± 0.026
0.754TrpIle: 0.754 ± 0.034
0.657TrpLys: 0.657 ± 0.028
1.612TrpLeu: 1.612 ± 0.055
0.333TrpMet: 0.333 ± 0.022
0.528TrpAsn: 0.528 ± 0.028
0.664TrpPro: 0.664 ± 0.038
0.544TrpGln: 0.544 ± 0.031
0.992TrpArg: 0.992 ± 0.04
0.844TrpSer: 0.844 ± 0.035
0.632TrpThr: 0.632 ± 0.033
0.861TrpVal: 0.861 ± 0.039
0.209TrpTrp: 0.209 ± 0.017
0.322TrpTyr: 0.322 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.237TyrAla: 2.237 ± 0.065
0.234TyrCys: 0.234 ± 0.017
1.55TyrAsp: 1.55 ± 0.047
1.33TyrGlu: 1.33 ± 0.047
1.015TyrPhe: 1.015 ± 0.045
2.22TyrGly: 2.22 ± 0.071
0.663TyrHis: 0.663 ± 0.032
1.36TyrIle: 1.36 ± 0.055
0.901TyrLys: 0.901 ± 0.039
2.264TyrLeu: 2.264 ± 0.069
0.507TyrMet: 0.507 ± 0.031
1.015TyrAsn: 1.015 ± 0.047
1.228TyrPro: 1.228 ± 0.042
0.997TyrGln: 0.997 ± 0.041
1.55TyrArg: 1.55 ± 0.051
1.458TyrSer: 1.458 ± 0.052
1.344TyrThr: 1.344 ± 0.056
1.62TyrVal: 1.62 ± 0.047
0.336TyrTrp: 0.336 ± 0.019
0.699TyrTyr: 0.699 ± 0.038
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1984 proteins (654950 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski