Amino acid dipepetide frequency for Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) (Peptostreptococcus magnus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.733AlaAla: 2.733 ± 0.1
0.607AlaCys: 0.607 ± 0.039
2.872AlaAsp: 2.872 ± 0.082
2.852AlaGlu: 2.852 ± 0.084
2.319AlaPhe: 2.319 ± 0.078
3.129AlaGly: 3.129 ± 0.094
0.741AlaHis: 0.741 ± 0.032
5.329AlaIle: 5.329 ± 0.118
5.149AlaLys: 5.149 ± 0.115
4.848AlaLeu: 4.848 ± 0.104
1.605AlaMet: 1.605 ± 0.06
2.867AlaAsn: 2.867 ± 0.079
1.282AlaPro: 1.282 ± 0.052
1.419AlaGln: 1.419 ± 0.053
1.917AlaArg: 1.917 ± 0.055
2.963AlaSer: 2.963 ± 0.068
2.805AlaThr: 2.805 ± 0.083
3.464AlaVal: 3.464 ± 0.088
0.255AlaTrp: 0.255 ± 0.021
1.84AlaTyr: 1.84 ± 0.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.548CysAla: 0.548 ± 0.035
0.154CysCys: 0.154 ± 0.021
0.824CysAsp: 0.824 ± 0.044
0.721CysGlu: 0.721 ± 0.036
0.419CysPhe: 0.419 ± 0.027
0.885CysGly: 0.885 ± 0.046
0.203CysHis: 0.203 ± 0.019
0.841CysIle: 0.841 ± 0.04
0.769CysLys: 0.769 ± 0.041
0.861CysLeu: 0.861 ± 0.04
0.263CysMet: 0.263 ± 0.022
0.528CysAsn: 0.528 ± 0.03
0.382CysPro: 0.382 ± 0.031
0.238CysGln: 0.238 ± 0.021
0.236CysArg: 0.236 ± 0.021
0.63CysSer: 0.63 ± 0.033
0.382CysThr: 0.382 ± 0.03
0.739CysVal: 0.739 ± 0.039
0.072CysTrp: 0.072 ± 0.011
0.394CysTyr: 0.394 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
2.654AspAla: 2.654 ± 0.075
0.757AspCys: 0.757 ± 0.036
4.312AspAsp: 4.312 ± 0.162
5.893AspGlu: 5.893 ± 0.11
3.569AspPhe: 3.569 ± 0.087
3.718AspGly: 3.718 ± 0.129
0.781AspHis: 0.781 ± 0.04
6.106AspIle: 6.106 ± 0.13
7.088AspLys: 7.088 ± 0.161
5.878AspLeu: 5.878 ± 0.121
1.687AspMet: 1.687 ± 0.049
4.012AspAsn: 4.012 ± 0.087
1.63AspPro: 1.63 ± 0.062
1.265AspGln: 1.265 ± 0.053
2.291AspArg: 2.291 ± 0.058
3.727AspSer: 3.727 ± 0.075
2.83AspThr: 2.83 ± 0.075
4.486AspVal: 4.486 ± 0.091
0.404AspTrp: 0.404 ± 0.03
3.527AspTyr: 3.527 ± 0.082
0.0AspXaa: 0.0 ± 0.0
Glu
3.147GluAla: 3.147 ± 0.092
0.592GluCys: 0.592 ± 0.035
5.23GluAsp: 5.23 ± 0.117
5.969GluGlu: 5.969 ± 0.114
3.353GluPhe: 3.353 ± 0.087
3.454GluGly: 3.454 ± 0.111
0.945GluHis: 0.945 ± 0.044
7.442GluIle: 7.442 ± 0.126
8.883GluLys: 8.883 ± 0.158
6.21GluLeu: 6.21 ± 0.116
1.996GluMet: 1.996 ± 0.065
6.416GluAsn: 6.416 ± 0.119
1.252GluPro: 1.252 ± 0.046
2.187GluGln: 2.187 ± 0.061
2.374GluArg: 2.374 ± 0.065
3.621GluSer: 3.621 ± 0.079
3.095GluThr: 3.095 ± 0.091
4.374GluVal: 4.374 ± 0.092
0.359GluTrp: 0.359 ± 0.033
3.132GluTyr: 3.132 ± 0.084
0.0GluXaa: 0.0 ± 0.0
Phe
2.562PheAla: 2.562 ± 0.067
0.519PheCys: 0.519 ± 0.03
3.496PheAsp: 3.496 ± 0.096
3.407PheGlu: 3.407 ± 0.086
2.088PhePhe: 2.088 ± 0.058
2.758PheGly: 2.758 ± 0.07
0.521PheHis: 0.521 ± 0.031
3.921PheIle: 3.921 ± 0.077
3.876PheLys: 3.876 ± 0.098
3.98PheLeu: 3.98 ± 0.083
1.243PheMet: 1.243 ± 0.054
2.84PheAsn: 2.84 ± 0.063
1.113PhePro: 1.113 ± 0.043
0.97PheGln: 0.97 ± 0.038
1.501PheArg: 1.501 ± 0.048
3.279PheSer: 3.279 ± 0.07
2.498PheThr: 2.498 ± 0.07
3.392PheVal: 3.392 ± 0.088
0.273PheTrp: 0.273 ± 0.021
2.031PheTyr: 2.031 ± 0.068
0.0PheXaa: 0.0 ± 0.0
Gly
3.358GlyAla: 3.358 ± 0.079
0.669GlyCys: 0.669 ± 0.041
3.14GlyAsp: 3.14 ± 0.081
3.945GlyGlu: 3.945 ± 0.105
3.067GlyPhe: 3.067 ± 0.07
3.496GlyGly: 3.496 ± 0.097
0.891GlyHis: 0.891 ± 0.041
5.372GlyIle: 5.372 ± 0.122
5.654GlyLys: 5.654 ± 0.142
5.215GlyLeu: 5.215 ± 0.123
1.59GlyMet: 1.59 ± 0.059
3.0GlyAsn: 3.0 ± 0.077
1.0GlyPro: 1.0 ± 0.041
1.562GlyGln: 1.562 ± 0.06
1.848GlyArg: 1.848 ± 0.062
3.365GlySer: 3.365 ± 0.085
2.83GlyThr: 2.83 ± 0.073
3.837GlyVal: 3.837 ± 0.087
0.392GlyTrp: 0.392 ± 0.03
2.793GlyTyr: 2.793 ± 0.079
0.0GlyXaa: 0.0 ± 0.0
His
0.684HisAla: 0.684 ± 0.032
0.147HisCys: 0.147 ± 0.013
0.945HisAsp: 0.945 ± 0.04
0.93HisGlu: 0.93 ± 0.038
0.618HisPhe: 0.618 ± 0.032
0.845HisGly: 0.845 ± 0.036
0.251HisHis: 0.251 ± 0.025
1.119HisIle: 1.119 ± 0.051
1.093HisLys: 1.093 ± 0.041
1.101HisLeu: 1.101 ± 0.043
0.318HisMet: 0.318 ± 0.024
0.845HisAsn: 0.845 ± 0.038
0.578HisPro: 0.578 ± 0.036
0.357HisGln: 0.357 ± 0.024
0.523HisArg: 0.523 ± 0.032
0.764HisSer: 0.764 ± 0.038
0.734HisThr: 0.734 ± 0.039
0.774HisVal: 0.774 ± 0.038
0.084HisTrp: 0.084 ± 0.012
0.593HisTyr: 0.593 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
5.131IleAla: 5.131 ± 0.114
1.034IleCys: 1.034 ± 0.041
6.374IleAsp: 6.374 ± 0.128
6.807IleGlu: 6.807 ± 0.12
4.077IlePhe: 4.077 ± 0.082
5.426IleGly: 5.426 ± 0.123
1.054IleHis: 1.054 ± 0.042
8.288IleIle: 8.288 ± 0.14
8.635IleLys: 8.635 ± 0.103
8.435IleLeu: 8.435 ± 0.153
2.301IleMet: 2.301 ± 0.068
5.746IleAsn: 5.746 ± 0.108
2.819IlePro: 2.819 ± 0.072
2.018IleGln: 2.018 ± 0.052
3.058IleArg: 3.058 ± 0.084
6.597IleSer: 6.597 ± 0.112
4.707IleThr: 4.707 ± 0.12
5.942IleVal: 5.942 ± 0.113
0.406IleTrp: 0.406 ± 0.029
3.457IleTyr: 3.457 ± 0.087
0.0IleXaa: 0.0 ± 0.0
Lys
4.816LysAla: 4.816 ± 0.13
0.705LysCys: 0.705 ± 0.041
7.065LysAsp: 7.065 ± 0.16
8.095LysGlu: 8.095 ± 0.139
3.98LysPhe: 3.98 ± 0.081
4.327LysGly: 4.327 ± 0.11
1.136LysHis: 1.136 ± 0.046
8.93LysIle: 8.93 ± 0.132
9.8LysLys: 9.8 ± 0.179
8.449LysLeu: 8.449 ± 0.143
2.493LysMet: 2.493 ± 0.07
7.383LysAsn: 7.383 ± 0.126
2.676LysPro: 2.676 ± 0.121
2.82LysGln: 2.82 ± 0.08
3.102LysArg: 3.102 ± 0.078
6.276LysSer: 6.276 ± 0.118
4.947LysThr: 4.947 ± 0.105
5.81LysVal: 5.81 ± 0.133
0.514LysTrp: 0.514 ± 0.032
4.399LysTyr: 4.399 ± 0.082
0.0LysXaa: 0.0 ± 0.0
Leu
4.9LeuAla: 4.9 ± 0.105
0.809LeuCys: 0.809 ± 0.041
6.001LeuAsp: 6.001 ± 0.115
6.363LeuGlu: 6.363 ± 0.119
3.789LeuPhe: 3.789 ± 0.086
5.186LeuGly: 5.186 ± 0.108
1.106LeuHis: 1.106 ± 0.046
7.995LeuIle: 7.995 ± 0.152
8.779LeuLys: 8.779 ± 0.13
7.554LeuLeu: 7.554 ± 0.146
2.517LeuMet: 2.517 ± 0.068
5.763LeuAsn: 5.763 ± 0.114
2.463LeuPro: 2.463 ± 0.06
2.199LeuGln: 2.199 ± 0.054
3.068LeuArg: 3.068 ± 0.083
6.448LeuSer: 6.448 ± 0.11
4.546LeuThr: 4.546 ± 0.09
5.361LeuVal: 5.361 ± 0.106
0.444LeuTrp: 0.444 ± 0.03
3.117LeuTyr: 3.117 ± 0.079
0.0LeuXaa: 0.0 ± 0.0
Met
1.58MetAla: 1.58 ± 0.059
0.268MetCys: 0.268 ± 0.023
1.711MetAsp: 1.711 ± 0.059
1.714MetGlu: 1.714 ± 0.067
1.17MetPhe: 1.17 ± 0.056
1.607MetGly: 1.607 ± 0.054
0.276MetHis: 0.276 ± 0.019
2.423MetIle: 2.423 ± 0.073
2.726MetLys: 2.726 ± 0.082
2.207MetLeu: 2.207 ± 0.068
0.813MetMet: 0.813 ± 0.038
1.805MetAsn: 1.805 ± 0.054
0.793MetPro: 0.793 ± 0.039
0.772MetGln: 0.772 ± 0.039
0.994MetArg: 0.994 ± 0.046
1.632MetSer: 1.632 ± 0.056
1.357MetThr: 1.357 ± 0.049
1.579MetVal: 1.579 ± 0.058
0.139MetTrp: 0.139 ± 0.016
0.962MetTyr: 0.962 ± 0.045
0.0MetXaa: 0.0 ± 0.0
Asn
3.006AsnAla: 3.006 ± 0.083
0.647AsnCys: 0.647 ± 0.036
3.777AsnAsp: 3.777 ± 0.087
4.588AsnGlu: 4.588 ± 0.098
2.83AsnPhe: 2.83 ± 0.07
3.382AsnGly: 3.382 ± 0.098
0.918AsnHis: 0.918 ± 0.038
6.222AsnIle: 6.222 ± 0.117
6.468AsnLys: 6.468 ± 0.13
6.146AsnLeu: 6.146 ± 0.112
1.662AsnMet: 1.662 ± 0.055
4.198AsnAsn: 4.198 ± 0.108
2.445AsnPro: 2.445 ± 0.082
1.867AsnGln: 1.867 ± 0.065
2.173AsnArg: 2.173 ± 0.071
4.161AsnSer: 4.161 ± 0.095
3.184AsnThr: 3.184 ± 0.065
4.015AsnVal: 4.015 ± 0.09
0.379AsnTrp: 0.379 ± 0.024
2.797AsnTyr: 2.797 ± 0.077
0.0AsnXaa: 0.0 ± 0.0
Pro
1.307ProAla: 1.307 ± 0.048
0.225ProCys: 0.225 ± 0.024
1.624ProAsp: 1.624 ± 0.059
2.247ProGlu: 2.247 ± 0.1
1.257ProPhe: 1.257 ± 0.047
1.661ProGly: 1.661 ± 0.083
0.397ProHis: 0.397 ± 0.03
2.45ProIle: 2.45 ± 0.066
2.395ProLys: 2.395 ± 0.078
2.056ProLeu: 2.056 ± 0.052
0.645ProMet: 0.645 ± 0.033
1.679ProAsn: 1.679 ± 0.057
0.444ProPro: 0.444 ± 0.03
0.893ProGln: 0.893 ± 0.05
0.779ProArg: 0.779 ± 0.04
1.619ProSer: 1.619 ± 0.054
1.639ProThr: 1.639 ± 0.067
2.08ProVal: 2.08 ± 0.058
0.166ProTrp: 0.166 ± 0.018
1.086ProTyr: 1.086 ± 0.042
0.0ProXaa: 0.0 ± 0.0
Gln
1.562GlnAla: 1.562 ± 0.052
0.174GlnCys: 0.174 ± 0.019
1.605GlnAsp: 1.605 ± 0.05
2.013GlnGlu: 2.013 ± 0.063
1.029GlnPhe: 1.029 ± 0.042
1.448GlnGly: 1.448 ± 0.054
0.297GlnHis: 0.297 ± 0.023
2.462GlnIle: 2.462 ± 0.067
2.762GlnLys: 2.762 ± 0.065
2.178GlnLeu: 2.178 ± 0.072
0.846GlnMet: 0.846 ± 0.047
1.803GlnAsn: 1.803 ± 0.062
0.637GlnPro: 0.637 ± 0.037
0.814GlnGln: 0.814 ± 0.042
1.077GlnArg: 1.077 ± 0.047
1.627GlnSer: 1.627 ± 0.051
1.315GlnThr: 1.315 ± 0.049
1.506GlnVal: 1.506 ± 0.047
0.171GlnTrp: 0.171 ± 0.018
0.999GlnTyr: 0.999 ± 0.044
0.0GlnXaa: 0.0 ± 0.0
Arg
1.644ArgAla: 1.644 ± 0.058
0.32ArgCys: 0.32 ± 0.022
2.121ArgAsp: 2.121 ± 0.074
2.644ArgGlu: 2.644 ± 0.078
1.599ArgPhe: 1.599 ± 0.051
1.753ArgGly: 1.753 ± 0.068
0.449ArgHis: 0.449 ± 0.028
3.221ArgIle: 3.221 ± 0.076
3.35ArgLys: 3.35 ± 0.076
3.07ArgLeu: 3.07 ± 0.072
0.972ArgMet: 0.972 ± 0.04
2.239ArgAsn: 2.239 ± 0.071
0.828ArgPro: 0.828 ± 0.038
1.064ArgGln: 1.064 ± 0.045
1.406ArgArg: 1.406 ± 0.058
1.557ArgSer: 1.557 ± 0.047
1.582ArgThr: 1.582 ± 0.053
2.182ArgVal: 2.182 ± 0.066
0.194ArgTrp: 0.194 ± 0.019
1.525ArgTyr: 1.525 ± 0.055
0.0ArgXaa: 0.0 ± 0.0
Ser
2.981SerAla: 2.981 ± 0.077
0.674SerCys: 0.674 ± 0.034
3.98SerAsp: 3.98 ± 0.091
4.218SerGlu: 4.218 ± 0.091
3.217SerPhe: 3.217 ± 0.078
3.948SerGly: 3.948 ± 0.092
0.972SerHis: 0.972 ± 0.04
5.681SerIle: 5.681 ± 0.11
5.927SerLys: 5.927 ± 0.104
5.865SerLeu: 5.865 ± 0.115
1.679SerMet: 1.679 ± 0.058
3.894SerAsn: 3.894 ± 0.09
1.525SerPro: 1.525 ± 0.046
1.843SerGln: 1.843 ± 0.059
1.992SerArg: 1.992 ± 0.06
4.089SerSer: 4.089 ± 0.091
3.164SerThr: 3.164 ± 0.079
4.172SerVal: 4.172 ± 0.088
0.364SerTrp: 0.364 ± 0.023
2.537SerTyr: 2.537 ± 0.072
0.0SerXaa: 0.0 ± 0.0
Thr
2.596ThrAla: 2.596 ± 0.086
0.427ThrCys: 0.427 ± 0.029
3.321ThrAsp: 3.321 ± 0.085
3.254ThrGlu: 3.254 ± 0.094
2.281ThrPhe: 2.281 ± 0.069
3.308ThrGly: 3.308 ± 0.073
0.813ThrHis: 0.813 ± 0.033
4.828ThrIle: 4.828 ± 0.105
4.529ThrLys: 4.529 ± 0.119
4.291ThrLeu: 4.291 ± 0.092
1.136ThrMet: 1.136 ± 0.042
2.966ThrAsn: 2.966 ± 0.067
1.729ThrPro: 1.729 ± 0.075
1.359ThrGln: 1.359 ± 0.049
1.684ThrArg: 1.684 ± 0.049
3.035ThrSer: 3.035 ± 0.069
3.005ThrThr: 3.005 ± 0.098
3.618ThrVal: 3.618 ± 0.141
0.236ThrTrp: 0.236 ± 0.021
1.853ThrTyr: 1.853 ± 0.061
0.0ThrXaa: 0.0 ± 0.0
Val
3.392ValAla: 3.392 ± 0.081
0.85ValCys: 0.85 ± 0.046
4.757ValAsp: 4.757 ± 0.087
4.947ValGlu: 4.947 ± 0.115
3.296ValPhe: 3.296 ± 0.085
3.986ValGly: 3.986 ± 0.108
0.823ValHis: 0.823 ± 0.044
5.736ValIle: 5.736 ± 0.108
5.486ValLys: 5.486 ± 0.115
5.855ValLeu: 5.855 ± 0.103
1.602ValMet: 1.602 ± 0.056
3.754ValAsn: 3.754 ± 0.087
1.684ValPro: 1.684 ± 0.056
1.414ValGln: 1.414 ± 0.048
2.09ValArg: 2.09 ± 0.067
4.327ValSer: 4.327 ± 0.082
3.269ValThr: 3.269 ± 0.11
4.861ValVal: 4.861 ± 0.111
0.323ValTrp: 0.323 ± 0.022
2.554ValTyr: 2.554 ± 0.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.342TrpAla: 0.342 ± 0.025
0.054TrpCys: 0.054 ± 0.01
0.34TrpAsp: 0.34 ± 0.028
0.362TrpGlu: 0.362 ± 0.026
0.221TrpPhe: 0.221 ± 0.019
0.375TrpGly: 0.375 ± 0.031
0.09TrpHis: 0.09 ± 0.013
0.536TrpIle: 0.536 ± 0.031
0.471TrpLys: 0.471 ± 0.031
0.468TrpLeu: 0.468 ± 0.029
0.188TrpMet: 0.188 ± 0.018
0.32TrpAsn: 0.32 ± 0.027
0.127TrpPro: 0.127 ± 0.017
0.204TrpGln: 0.204 ± 0.022
0.176TrpArg: 0.176 ± 0.018
0.297TrpSer: 0.297 ± 0.022
0.27TrpThr: 0.27 ± 0.023
0.347TrpVal: 0.347 ± 0.026
0.047TrpTrp: 0.047 ± 0.008
0.25TrpTyr: 0.25 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.053TyrAla: 2.053 ± 0.066
0.457TyrCys: 0.457 ± 0.027
3.122TyrAsp: 3.122 ± 0.077
3.062TyrGlu: 3.062 ± 0.084
2.091TyrPhe: 2.091 ± 0.062
2.334TyrGly: 2.334 ± 0.067
0.638TyrHis: 0.638 ± 0.033
3.41TyrIle: 3.41 ± 0.081
3.883TyrLys: 3.883 ± 0.085
3.738TyrLeu: 3.738 ± 0.1
0.969TyrMet: 0.969 ± 0.04
2.808TyrAsn: 2.808 ± 0.083
1.24TyrPro: 1.24 ± 0.054
1.059TyrGln: 1.059 ± 0.047
1.429TyrArg: 1.429 ± 0.042
2.71TyrSer: 2.71 ± 0.072
2.11TyrThr: 2.11 ± 0.061
2.468TyrVal: 2.468 ± 0.068
0.263TyrTrp: 0.263 ± 0.025
1.823TyrTyr: 1.823 ± 0.062
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1813 proteins (596766 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski