Amino acid dipepetide frequency for Azospirillum baldaniorum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.638AlaAla: 19.638 ± 0.137
1.161AlaCys: 1.161 ± 0.022
7.418AlaAsp: 7.418 ± 0.068
8.011AlaGlu: 8.011 ± 0.076
4.227AlaPhe: 4.227 ± 0.043
12.28AlaGly: 12.28 ± 0.125
2.306AlaHis: 2.306 ± 0.039
5.168AlaIle: 5.168 ± 0.049
3.481AlaLys: 3.481 ± 0.053
14.926AlaLeu: 14.926 ± 0.118
3.467AlaMet: 3.467 ± 0.042
2.773AlaAsn: 2.773 ± 0.043
6.468AlaPro: 6.468 ± 0.076
3.967AlaGln: 3.967 ± 0.042
9.359AlaArg: 9.359 ± 0.087
5.844AlaSer: 5.844 ± 0.055
6.285AlaThr: 6.285 ± 0.09
10.658AlaVal: 10.658 ± 0.073
1.515AlaTrp: 1.515 ± 0.033
2.34AlaTyr: 2.34 ± 0.035
0.0AlaXaa: 0.0 ± 0.0
Cys
1.08CysAla: 1.08 ± 0.023
0.132CysCys: 0.132 ± 0.009
0.493CysAsp: 0.493 ± 0.014
0.364CysGlu: 0.364 ± 0.013
0.304CysPhe: 0.304 ± 0.013
0.982CysGly: 0.982 ± 0.021
0.255CysHis: 0.255 ± 0.011
0.348CysIle: 0.348 ± 0.014
0.174CysLys: 0.174 ± 0.01
0.793CysLeu: 0.793 ± 0.02
0.173CysMet: 0.173 ± 0.009
0.199CysAsn: 0.199 ± 0.01
0.525CysPro: 0.525 ± 0.018
0.224CysGln: 0.224 ± 0.01
0.839CysArg: 0.839 ± 0.022
0.433CysSer: 0.433 ± 0.016
0.429CysThr: 0.429 ± 0.014
0.624CysVal: 0.624 ± 0.017
0.144CysTrp: 0.144 ± 0.008
0.18CysTyr: 0.18 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
7.187AspAla: 7.187 ± 0.075
0.463AspCys: 0.463 ± 0.015
2.979AspAsp: 2.979 ± 0.05
3.155AspGlu: 3.155 ± 0.042
1.826AspPhe: 1.826 ± 0.03
6.091AspGly: 6.091 ± 0.076
1.355AspHis: 1.355 ± 0.026
2.484AspIle: 2.484 ± 0.035
1.283AspLys: 1.283 ± 0.026
6.149AspLeu: 6.149 ± 0.057
1.106AspMet: 1.106 ± 0.023
1.113AspAsn: 1.113 ± 0.03
3.749AspPro: 3.749 ± 0.044
1.563AspGln: 1.563 ± 0.026
5.27AspArg: 5.27 ± 0.057
2.446AspSer: 2.446 ± 0.041
2.737AspThr: 2.737 ± 0.057
3.96AspVal: 3.96 ± 0.04
0.887AspTrp: 0.887 ± 0.02
1.207AspTyr: 1.207 ± 0.026
0.0AspXaa: 0.0 ± 0.001
Glu
7.667GluAla: 7.667 ± 0.071
0.309GluCys: 0.309 ± 0.012
2.625GluAsp: 2.625 ± 0.036
3.35GluGlu: 3.35 ± 0.046
1.458GluPhe: 1.458 ± 0.026
4.228GluGly: 4.228 ± 0.051
1.133GluHis: 1.133 ± 0.024
2.542GluIle: 2.542 ± 0.037
1.674GluLys: 1.674 ± 0.034
4.972GluLeu: 4.972 ± 0.058
1.301GluMet: 1.301 ± 0.026
1.198GluAsn: 1.198 ± 0.022
2.864GluPro: 2.864 ± 0.04
2.012GluGln: 2.012 ± 0.035
5.792GluArg: 5.792 ± 0.063
2.315GluSer: 2.315 ± 0.035
3.073GluThr: 3.073 ± 0.04
3.819GluVal: 3.819 ± 0.047
0.629GluTrp: 0.629 ± 0.017
0.786GluTyr: 0.786 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
4.194PheAla: 4.194 ± 0.054
0.348PheCys: 0.348 ± 0.012
2.264PheAsp: 2.264 ± 0.03
1.749PheGlu: 1.749 ± 0.03
1.163PhePhe: 1.163 ± 0.026
3.323PheGly: 3.323 ± 0.044
0.769PheHis: 0.769 ± 0.02
1.289PheIle: 1.289 ± 0.028
0.824PheLys: 0.824 ± 0.022
3.335PheLeu: 3.335 ± 0.045
0.65PheMet: 0.65 ± 0.02
0.914PheAsn: 0.914 ± 0.022
1.627PhePro: 1.627 ± 0.027
1.024PheGln: 1.024 ± 0.021
2.349PheArg: 2.349 ± 0.029
1.709PheSer: 1.709 ± 0.029
1.971PheThr: 1.971 ± 0.039
2.474PheVal: 2.474 ± 0.033
0.48PheTrp: 0.48 ± 0.018
0.777PheTyr: 0.777 ± 0.021
0.0PheXaa: 0.0 ± 0.0
Gly
10.52GlyAla: 10.52 ± 0.096
0.95GlyCys: 0.95 ± 0.025
4.862GlyAsp: 4.862 ± 0.076
4.565GlyGlu: 4.565 ± 0.056
3.35GlyPhe: 3.35 ± 0.038
8.832GlyGly: 8.832 ± 0.136
2.037GlyHis: 2.037 ± 0.034
4.042GlyIle: 4.042 ± 0.047
2.778GlyLys: 2.778 ± 0.042
9.531GlyLeu: 9.531 ± 0.082
2.426GlyMet: 2.426 ± 0.037
2.359GlyAsn: 2.359 ± 0.074
4.133GlyPro: 4.133 ± 0.053
3.001GlyGln: 3.001 ± 0.045
7.449GlyArg: 7.449 ± 0.083
4.644GlySer: 4.644 ± 0.08
5.425GlyThr: 5.425 ± 0.095
6.826GlyVal: 6.826 ± 0.066
1.519GlyTrp: 1.519 ± 0.029
2.098GlyTyr: 2.098 ± 0.032
0.0GlyXaa: 0.0 ± 0.0
His
2.489HisAla: 2.489 ± 0.036
0.237HisCys: 0.237 ± 0.009
1.18HisAsp: 1.18 ± 0.023
0.953HisGlu: 0.953 ± 0.023
0.749HisPhe: 0.749 ± 0.018
2.122HisGly: 2.122 ± 0.036
0.695HisHis: 0.695 ± 0.02
0.817HisIle: 0.817 ± 0.022
0.486HisLys: 0.486 ± 0.019
2.176HisLeu: 2.176 ± 0.034
0.441HisMet: 0.441 ± 0.015
0.441HisAsn: 0.441 ± 0.014
1.604HisPro: 1.604 ± 0.033
0.628HisGln: 0.628 ± 0.02
2.102HisArg: 2.102 ± 0.043
0.93HisSer: 0.93 ± 0.021
0.935HisThr: 0.935 ± 0.02
1.401HisVal: 1.401 ± 0.027
0.321HisTrp: 0.321 ± 0.011
0.465HisTyr: 0.465 ± 0.015
0.0HisXaa: 0.0 ± 0.0
Ile
6.147IleAla: 6.147 ± 0.057
0.354IleCys: 0.354 ± 0.013
3.007IleAsp: 3.007 ± 0.039
2.519IleGlu: 2.519 ± 0.037
1.166IlePhe: 1.166 ± 0.029
4.427IleGly: 4.427 ± 0.051
0.888IleHis: 0.888 ± 0.024
1.54IleIle: 1.54 ± 0.033
1.005IleLys: 1.005 ± 0.025
4.125IleLeu: 4.125 ± 0.045
0.74IleMet: 0.74 ± 0.02
1.127IleAsn: 1.127 ± 0.025
2.208IlePro: 2.208 ± 0.033
1.194IleGln: 1.194 ± 0.022
3.027IleArg: 3.027 ± 0.044
1.89IleSer: 1.89 ± 0.034
2.311IleThr: 2.311 ± 0.042
3.437IleVal: 3.437 ± 0.047
0.408IleTrp: 0.408 ± 0.014
0.778IleTyr: 0.778 ± 0.02
0.0IleXaa: 0.0 ± 0.0
Lys
3.762LysAla: 3.762 ± 0.059
0.12LysCys: 0.12 ± 0.007
1.544LysAsp: 1.544 ± 0.032
1.406LysGlu: 1.406 ± 0.029
0.634LysPhe: 0.634 ± 0.017
2.351LysGly: 2.351 ± 0.035
0.493LysHis: 0.493 ± 0.014
1.187LysIle: 1.187 ± 0.026
0.926LysLys: 0.926 ± 0.027
2.63LysLeu: 2.63 ± 0.043
0.592LysMet: 0.592 ± 0.015
0.656LysAsn: 0.656 ± 0.017
1.936LysPro: 1.936 ± 0.035
0.776LysGln: 0.776 ± 0.023
2.117LysArg: 2.117 ± 0.033
1.341LysSer: 1.341 ± 0.03
1.62LysThr: 1.62 ± 0.028
1.975LysVal: 1.975 ± 0.038
0.25LysTrp: 0.25 ± 0.011
0.458LysTyr: 0.458 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
14.04LeuAla: 14.04 ± 0.094
0.999LeuCys: 0.999 ± 0.022
6.397LeuAsp: 6.397 ± 0.064
5.261LeuGlu: 5.261 ± 0.057
3.717LeuPhe: 3.717 ± 0.041
8.638LeuGly: 8.638 ± 0.068
2.117LeuHis: 2.117 ± 0.04
4.159LeuIle: 4.159 ± 0.048
3.029LeuLys: 3.029 ± 0.039
10.672LeuLeu: 10.672 ± 0.106
2.281LeuMet: 2.281 ± 0.039
2.5LeuAsn: 2.5 ± 0.032
6.252LeuPro: 6.252 ± 0.06
2.589LeuGln: 2.589 ± 0.037
8.259LeuArg: 8.259 ± 0.086
6.44LeuSer: 6.44 ± 0.059
6.2LeuThr: 6.2 ± 0.086
7.642LeuVal: 7.642 ± 0.062
1.285LeuTrp: 1.285 ± 0.024
1.98LeuTyr: 1.98 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
3.276MetAla: 3.276 ± 0.037
0.133MetCys: 0.133 ± 0.008
1.284MetAsp: 1.284 ± 0.028
1.175MetGlu: 1.175 ± 0.022
0.578MetPhe: 0.578 ± 0.017
1.813MetGly: 1.813 ± 0.029
0.404MetHis: 0.404 ± 0.012
1.048MetIle: 1.048 ± 0.025
0.746MetLys: 0.746 ± 0.02
2.306MetLeu: 2.306 ± 0.036
0.63MetMet: 0.63 ± 0.019
0.628MetAsn: 0.628 ± 0.017
1.524MetPro: 1.524 ± 0.027
0.665MetGln: 0.665 ± 0.019
1.666MetArg: 1.666 ± 0.029
1.442MetSer: 1.442 ± 0.024
1.835MetThr: 1.835 ± 0.03
1.764MetVal: 1.764 ± 0.033
0.192MetTrp: 0.192 ± 0.008
0.248MetTyr: 0.248 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.124AsnAla: 3.124 ± 0.042
0.204AsnCys: 0.204 ± 0.01
1.38AsnAsp: 1.38 ± 0.047
1.01AsnGlu: 1.01 ± 0.023
0.724AsnPhe: 0.724 ± 0.018
2.505AsnGly: 2.505 ± 0.061
0.493AsnHis: 0.493 ± 0.014
1.046AsnIle: 1.046 ± 0.024
0.558AsnLys: 0.558 ± 0.017
2.493AsnLeu: 2.493 ± 0.043
0.467AsnMet: 0.467 ± 0.016
0.647AsnAsn: 0.647 ± 0.023
1.819AsnPro: 1.819 ± 0.03
0.71AsnGln: 0.71 ± 0.02
1.918AsnArg: 1.918 ± 0.033
1.098AsnSer: 1.098 ± 0.032
1.241AsnThr: 1.241 ± 0.033
1.687AsnVal: 1.687 ± 0.037
0.339AsnTrp: 0.339 ± 0.015
0.512AsnTyr: 0.512 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
7.756ProAla: 7.756 ± 0.079
0.436ProCys: 0.436 ± 0.016
4.175ProAsp: 4.175 ± 0.051
3.686ProGlu: 3.686 ± 0.054
1.979ProPhe: 1.979 ± 0.03
5.278ProGly: 5.278 ± 0.064
1.151ProHis: 1.151 ± 0.026
1.987ProIle: 1.987 ± 0.033
1.495ProLys: 1.495 ± 0.031
5.407ProLeu: 5.407 ± 0.055
1.322ProMet: 1.322 ± 0.026
1.308ProAsn: 1.308 ± 0.026
3.821ProPro: 3.821 ± 0.059
1.659ProGln: 1.659 ± 0.029
3.701ProArg: 3.701 ± 0.053
3.07ProSer: 3.07 ± 0.044
2.801ProThr: 2.801 ± 0.046
4.918ProVal: 4.918 ± 0.047
0.8ProTrp: 0.8 ± 0.022
1.129ProTyr: 1.129 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
4.209GlnAla: 4.209 ± 0.047
0.189GlnCys: 0.189 ± 0.009
1.483GlnAsp: 1.483 ± 0.027
1.488GlnGlu: 1.488 ± 0.031
0.9GlnPhe: 0.9 ± 0.022
2.561GlnGly: 2.561 ± 0.04
0.646GlnHis: 0.646 ± 0.02
1.441GlnIle: 1.441 ± 0.028
0.851GlnLys: 0.851 ± 0.02
2.543GlnLeu: 2.543 ± 0.033
0.753GlnMet: 0.753 ± 0.019
0.735GlnAsn: 0.735 ± 0.019
2.061GlnPro: 2.061 ± 0.038
1.156GlnGln: 1.156 ± 0.03
2.68GlnArg: 2.68 ± 0.041
1.564GlnSer: 1.564 ± 0.032
1.744GlnThr: 1.744 ± 0.032
2.165GlnVal: 2.165 ± 0.028
0.371GlnTrp: 0.371 ± 0.013
0.51GlnTyr: 0.51 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
9.085ArgAla: 9.085 ± 0.09
0.763ArgCys: 0.763 ± 0.02
4.311ArgAsp: 4.311 ± 0.051
3.959ArgGlu: 3.959 ± 0.048
3.073ArgPhe: 3.073 ± 0.038
5.76ArgGly: 5.76 ± 0.064
2.202ArgHis: 2.202 ± 0.039
3.803ArgIle: 3.803 ± 0.04
2.065ArgLys: 2.065 ± 0.037
9.264ArgLeu: 9.264 ± 0.087
2.055ArgMet: 2.055 ± 0.029
1.964ArgAsn: 1.964 ± 0.031
4.705ArgPro: 4.705 ± 0.071
2.735ArgGln: 2.735 ± 0.04
8.098ArgArg: 8.098 ± 0.106
4.029ArgSer: 4.029 ± 0.048
3.909ArgThr: 3.909 ± 0.042
5.467ArgVal: 5.467 ± 0.052
1.213ArgTrp: 1.213 ± 0.025
1.634ArgTyr: 1.634 ± 0.029
0.0ArgXaa: 0.0 ± 0.0
Ser
6.193SerAla: 6.193 ± 0.064
0.459SerCys: 0.459 ± 0.017
2.617SerAsp: 2.617 ± 0.035
2.167SerGlu: 2.167 ± 0.028
1.962SerPhe: 1.962 ± 0.031
5.596SerGly: 5.596 ± 0.07
1.047SerHis: 1.047 ± 0.023
2.212SerIle: 2.212 ± 0.045
1.259SerLys: 1.259 ± 0.028
5.271SerLeu: 5.271 ± 0.057
1.195SerMet: 1.195 ± 0.028
1.241SerAsn: 1.241 ± 0.033
2.929SerPro: 2.929 ± 0.039
1.424SerGln: 1.424 ± 0.024
3.539SerArg: 3.539 ± 0.044
2.708SerSer: 2.708 ± 0.055
2.595SerThr: 2.595 ± 0.051
3.954SerVal: 3.954 ± 0.045
0.753SerTrp: 0.753 ± 0.019
1.122SerTyr: 1.122 ± 0.024
0.0SerXaa: 0.0 ± 0.0
Thr
7.442ThrAla: 7.442 ± 0.096
0.389ThrCys: 0.389 ± 0.012
3.02ThrAsp: 3.02 ± 0.046
2.603ThrGlu: 2.603 ± 0.042
1.685ThrPhe: 1.685 ± 0.032
5.522ThrGly: 5.522 ± 0.085
0.98ThrHis: 0.98 ± 0.021
2.553ThrIle: 2.553 ± 0.045
1.207ThrLys: 1.207 ± 0.026
6.342ThrLeu: 6.342 ± 0.086
1.19ThrMet: 1.19 ± 0.026
1.313ThrAsn: 1.313 ± 0.041
3.577ThrPro: 3.577 ± 0.054
1.378ThrGln: 1.378 ± 0.03
3.37ThrArg: 3.37 ± 0.041
2.51ThrSer: 2.51 ± 0.052
2.992ThrThr: 2.992 ± 0.074
5.325ThrVal: 5.325 ± 0.088
0.585ThrTrp: 0.585 ± 0.018
1.031ThrTyr: 1.031 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
9.862ValAla: 9.862 ± 0.077
0.706ValCys: 0.706 ± 0.017
4.008ValAsp: 4.008 ± 0.041
4.683ValGlu: 4.683 ± 0.047
2.543ValPhe: 2.543 ± 0.036
6.123ValGly: 6.123 ± 0.069
1.467ValHis: 1.467 ± 0.028
3.337ValIle: 3.337 ± 0.044
2.042ValLys: 2.042 ± 0.035
7.997ValLeu: 7.997 ± 0.067
1.843ValMet: 1.843 ± 0.036
1.958ValAsn: 1.958 ± 0.031
4.363ValPro: 4.363 ± 0.052
2.251ValGln: 2.251 ± 0.032
5.619ValArg: 5.619 ± 0.053
4.075ValSer: 4.075 ± 0.05
5.021ValThr: 5.021 ± 0.092
6.336ValVal: 6.336 ± 0.06
0.992ValTrp: 0.992 ± 0.024
1.446ValTyr: 1.446 ± 0.029
0.0ValXaa: 0.0 ± 0.0
Trp
1.3TrpAla: 1.3 ± 0.028
0.139TrpCys: 0.139 ± 0.007
0.679TrpAsp: 0.679 ± 0.019
0.591TrpGlu: 0.591 ± 0.018
0.511TrpPhe: 0.511 ± 0.017
0.931TrpGly: 0.931 ± 0.022
0.322TrpHis: 0.322 ± 0.011
0.585TrpIle: 0.585 ± 0.016
0.406TrpLys: 0.406 ± 0.014
1.593TrpLeu: 1.593 ± 0.028
0.357TrpMet: 0.357 ± 0.013
0.416TrpAsn: 0.416 ± 0.015
0.702TrpPro: 0.702 ± 0.018
0.485TrpGln: 0.485 ± 0.015
1.25TrpArg: 1.25 ± 0.025
0.787TrpSer: 0.787 ± 0.021
0.821TrpThr: 0.821 ± 0.021
0.839TrpVal: 0.839 ± 0.021
0.235TrpTrp: 0.235 ± 0.011
0.287TrpTyr: 0.287 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.321TyrAla: 2.321 ± 0.034
0.204TyrCys: 0.204 ± 0.01
1.286TyrAsp: 1.286 ± 0.026
1.054TyrGlu: 1.054 ± 0.025
0.682TyrPhe: 0.682 ± 0.021
1.984TyrGly: 1.984 ± 0.037
0.412TyrHis: 0.412 ± 0.016
0.71TyrIle: 0.71 ± 0.018
0.485TyrLys: 0.485 ± 0.015
1.931TyrLeu: 1.931 ± 0.03
0.367TyrMet: 0.367 ± 0.013
0.485TyrAsn: 0.485 ± 0.017
1.011TyrPro: 1.011 ± 0.022
0.61TyrGln: 0.61 ± 0.019
1.691TyrArg: 1.691 ± 0.032
0.968TyrSer: 0.968 ± 0.02
1.065TyrThr: 1.065 ± 0.033
1.4TyrVal: 1.4 ± 0.027
0.32TyrTrp: 0.32 ± 0.012
0.467TyrTyr: 0.467 ± 0.017
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.001
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7541 proteins (2208573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski