Amino acid dipepetide frequency for Human adenovirus B serotype 3 (HAdV-3) (Human adenovirus 3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.314AlaAla: 7.314 ± 1.138
1.258AlaCys: 1.258 ± 0.444
2.517AlaAsp: 2.517 ± 0.445
3.146AlaGlu: 3.146 ± 0.597
2.517AlaPhe: 2.517 ± 0.502
3.932AlaGly: 3.932 ± 0.563
1.652AlaHis: 1.652 ± 0.324
3.225AlaIle: 3.225 ± 0.586
1.652AlaLys: 1.652 ± 0.399
6.921AlaLeu: 6.921 ± 0.901
1.73AlaMet: 1.73 ± 0.429
3.382AlaAsn: 3.382 ± 0.589
4.955AlaPro: 4.955 ± 0.663
2.123AlaGln: 2.123 ± 0.361
4.719AlaArg: 4.719 ± 0.717
5.663AlaSer: 5.663 ± 0.443
5.427AlaThr: 5.427 ± 0.654
6.37AlaVal: 6.37 ± 0.711
0.708AlaTrp: 0.708 ± 0.193
2.595AlaTyr: 2.595 ± 0.434
0.0AlaXaa: 0.0 ± 0.0
Cys
1.494CysAla: 1.494 ± 0.415
1.18CysCys: 1.18 ± 0.337
0.944CysAsp: 0.944 ± 0.258
0.865CysGlu: 0.865 ± 0.299
0.472CysPhe: 0.472 ± 0.191
1.573CysGly: 1.573 ± 0.403
0.551CysHis: 0.551 ± 0.201
1.573CysIle: 1.573 ± 0.478
0.629CysLys: 0.629 ± 0.267
1.416CysLeu: 1.416 ± 0.356
0.708CysMet: 0.708 ± 0.32
1.258CysAsn: 1.258 ± 0.364
0.865CysPro: 0.865 ± 0.304
0.236CysGln: 0.236 ± 0.163
0.786CysArg: 0.786 ± 0.258
1.101CysSer: 1.101 ± 0.317
0.944CysThr: 0.944 ± 0.323
1.101CysVal: 1.101 ± 0.338
0.472CysTrp: 0.472 ± 0.223
1.337CysTyr: 1.337 ± 0.301
0.0CysXaa: 0.0 ± 0.0
Asp
3.067AspAla: 3.067 ± 0.429
0.944AspCys: 0.944 ± 0.292
2.91AspAsp: 2.91 ± 0.597
4.247AspGlu: 4.247 ± 0.688
1.573AspPhe: 1.573 ± 0.343
3.775AspGly: 3.775 ± 0.59
1.416AspHis: 1.416 ± 0.305
2.359AspIle: 2.359 ± 0.521
1.652AspLys: 1.652 ± 0.3
5.584AspLeu: 5.584 ± 0.984
1.809AspMet: 1.809 ± 0.31
1.888AspAsn: 1.888 ± 0.376
3.618AspPro: 3.618 ± 0.498
0.944AspGln: 0.944 ± 0.262
3.539AspArg: 3.539 ± 0.725
3.696AspSer: 3.696 ± 0.701
1.966AspThr: 1.966 ± 0.49
2.674AspVal: 2.674 ± 0.451
0.786AspTrp: 0.786 ± 0.262
1.809AspTyr: 1.809 ± 0.376
0.0AspXaa: 0.0 ± 0.0
Glu
4.168GluAla: 4.168 ± 0.682
1.022GluCys: 1.022 ± 0.261
4.64GluAsp: 4.64 ± 0.655
7.707GluGlu: 7.707 ± 1.554
1.966GluPhe: 1.966 ± 0.403
4.247GluGly: 4.247 ± 0.716
1.258GluHis: 1.258 ± 0.327
2.831GluIle: 2.831 ± 0.561
2.753GluLys: 2.753 ± 0.442
5.899GluLeu: 5.899 ± 0.792
1.494GluMet: 1.494 ± 0.332
2.674GluAsn: 2.674 ± 0.444
2.517GluPro: 2.517 ± 0.471
2.753GluGln: 2.753 ± 0.425
4.09GluArg: 4.09 ± 0.821
2.281GluSer: 2.281 ± 0.483
3.775GluThr: 3.775 ± 0.539
4.326GluVal: 4.326 ± 0.652
0.551GluTrp: 0.551 ± 0.253
1.258GluTyr: 1.258 ± 0.366
0.0GluXaa: 0.0 ± 0.0
Phe
1.652PheAla: 1.652 ± 0.357
0.472PheCys: 0.472 ± 0.197
2.517PheAsp: 2.517 ± 0.421
1.573PheGlu: 1.573 ± 0.334
1.809PhePhe: 1.809 ± 0.463
1.888PheGly: 1.888 ± 0.478
1.022PheHis: 1.022 ± 0.222
1.966PheIle: 1.966 ± 0.351
1.652PheLys: 1.652 ± 0.331
3.775PheLeu: 3.775 ± 0.675
1.494PheMet: 1.494 ± 0.348
1.73PheAsn: 1.73 ± 0.34
2.281PhePro: 2.281 ± 0.309
1.809PheGln: 1.809 ± 0.284
2.045PheArg: 2.045 ± 0.322
2.989PheSer: 2.989 ± 0.399
2.281PheThr: 2.281 ± 0.345
2.517PheVal: 2.517 ± 0.432
0.079PheTrp: 0.079 ± 0.077
1.337PheTyr: 1.337 ± 0.297
0.0PheXaa: 0.0 ± 0.0
Gly
4.797GlyAla: 4.797 ± 0.684
1.416GlyCys: 1.416 ± 0.351
2.831GlyAsp: 2.831 ± 0.434
3.067GlyGlu: 3.067 ± 0.532
2.753GlyPhe: 2.753 ± 0.45
6.449GlyGly: 6.449 ± 0.886
1.888GlyHis: 1.888 ± 0.387
3.932GlyIle: 3.932 ± 0.583
1.809GlyLys: 1.809 ± 0.335
5.033GlyLeu: 5.033 ± 0.667
1.73GlyMet: 1.73 ± 0.524
2.359GlyAsn: 2.359 ± 0.528
3.225GlyPro: 3.225 ± 0.433
2.281GlyGln: 2.281 ± 0.408
5.269GlyArg: 5.269 ± 0.614
4.247GlySer: 4.247 ± 0.64
2.674GlyThr: 2.674 ± 0.504
3.932GlyVal: 3.932 ± 0.694
0.865GlyTrp: 0.865 ± 0.273
2.045GlyTyr: 2.045 ± 0.398
0.0GlyXaa: 0.0 ± 0.0
His
1.573HisAla: 1.573 ± 0.409
0.786HisCys: 0.786 ± 0.282
0.629HisAsp: 0.629 ± 0.192
1.416HisGlu: 1.416 ± 0.375
1.022HisPhe: 1.022 ± 0.301
1.809HisGly: 1.809 ± 0.231
0.786HisHis: 0.786 ± 0.214
1.18HisIle: 1.18 ± 0.305
0.786HisLys: 0.786 ± 0.272
2.123HisLeu: 2.123 ± 0.53
0.315HisMet: 0.315 ± 0.163
1.101HisAsn: 1.101 ± 0.294
2.595HisPro: 2.595 ± 0.571
0.708HisGln: 0.708 ± 0.231
2.438HisArg: 2.438 ± 0.421
1.416HisSer: 1.416 ± 0.298
1.101HisThr: 1.101 ± 0.225
1.337HisVal: 1.337 ± 0.278
0.236HisTrp: 0.236 ± 0.169
0.393HisTyr: 0.393 ± 0.153
0.0HisXaa: 0.0 ± 0.0
Ile
2.989IleAla: 2.989 ± 0.513
0.944IleCys: 0.944 ± 0.377
1.573IleAsp: 1.573 ± 0.319
1.966IleGlu: 1.966 ± 0.329
2.202IlePhe: 2.202 ± 0.474
2.438IleGly: 2.438 ± 0.475
0.944IleHis: 0.944 ± 0.257
2.91IleIle: 2.91 ± 0.763
2.202IleLys: 2.202 ± 0.475
4.719IleLeu: 4.719 ± 0.82
1.888IleMet: 1.888 ± 0.465
2.517IleAsn: 2.517 ± 0.438
3.46IlePro: 3.46 ± 0.538
2.202IleGln: 2.202 ± 0.358
2.595IleArg: 2.595 ± 0.546
3.696IleSer: 3.696 ± 0.458
3.932IleThr: 3.932 ± 0.546
3.303IleVal: 3.303 ± 0.53
0.315IleTrp: 0.315 ± 0.166
1.416IleTyr: 1.416 ± 0.331
0.0IleXaa: 0.0 ± 0.0
Lys
2.202LysAla: 2.202 ± 0.307
0.944LysCys: 0.944 ± 0.266
1.73LysAsp: 1.73 ± 0.359
2.674LysGlu: 2.674 ± 0.566
1.416LysPhe: 1.416 ± 0.339
2.438LysGly: 2.438 ± 0.548
0.708LysHis: 0.708 ± 0.249
2.595LysIle: 2.595 ± 0.444
2.831LysLys: 2.831 ± 0.506
4.168LysLeu: 4.168 ± 0.705
1.18LysMet: 1.18 ± 0.37
1.966LysAsn: 1.966 ± 0.415
2.517LysPro: 2.517 ± 0.617
1.494LysGln: 1.494 ± 0.322
2.989LysArg: 2.989 ± 0.666
2.517LysSer: 2.517 ± 0.515
2.359LysThr: 2.359 ± 0.422
2.045LysVal: 2.045 ± 0.396
0.472LysTrp: 0.472 ± 0.161
1.18LysTyr: 1.18 ± 0.305
0.0LysXaa: 0.0 ± 0.0
Leu
5.899LeuAla: 5.899 ± 0.603
1.73LeuCys: 1.73 ± 0.367
5.112LeuAsp: 5.112 ± 0.728
6.449LeuGlu: 6.449 ± 0.782
2.281LeuPhe: 2.281 ± 0.439
5.741LeuGly: 5.741 ± 0.792
2.517LeuHis: 2.517 ± 0.497
3.854LeuIle: 3.854 ± 0.6
4.168LeuLys: 4.168 ± 0.684
8.573LeuLeu: 8.573 ± 0.991
2.91LeuMet: 2.91 ± 0.388
3.854LeuAsn: 3.854 ± 0.546
6.842LeuPro: 6.842 ± 0.837
4.168LeuGln: 4.168 ± 0.598
6.921LeuArg: 6.921 ± 0.631
5.427LeuSer: 5.427 ± 0.799
5.82LeuThr: 5.82 ± 0.669
5.584LeuVal: 5.584 ± 0.584
1.573LeuTrp: 1.573 ± 0.332
3.382LeuTyr: 3.382 ± 0.627
0.0LeuXaa: 0.0 ± 0.0
Met
2.359MetAla: 2.359 ± 0.445
0.315MetCys: 0.315 ± 0.145
1.022MetAsp: 1.022 ± 0.23
1.966MetGlu: 1.966 ± 0.356
0.865MetPhe: 0.865 ± 0.263
1.652MetGly: 1.652 ± 0.327
1.258MetHis: 1.258 ± 0.409
1.101MetIle: 1.101 ± 0.334
1.18MetLys: 1.18 ± 0.306
2.753MetLeu: 2.753 ± 0.45
0.865MetMet: 0.865 ± 0.252
1.101MetAsn: 1.101 ± 0.353
1.888MetPro: 1.888 ± 0.324
1.494MetGln: 1.494 ± 0.309
2.123MetArg: 2.123 ± 0.46
1.888MetSer: 1.888 ± 0.335
1.888MetThr: 1.888 ± 0.495
1.022MetVal: 1.022 ± 0.341
0.315MetTrp: 0.315 ± 0.168
0.865MetTyr: 0.865 ± 0.231
0.0MetXaa: 0.0 ± 0.0
Asn
2.281AsnAla: 2.281 ± 0.463
0.472AsnCys: 0.472 ± 0.198
2.123AsnAsp: 2.123 ± 0.506
2.123AsnGlu: 2.123 ± 0.362
2.595AsnPhe: 2.595 ± 0.462
2.753AsnGly: 2.753 ± 0.476
0.865AsnHis: 0.865 ± 0.273
2.91AsnIle: 2.91 ± 0.634
1.652AsnLys: 1.652 ± 0.369
3.539AsnLeu: 3.539 ± 0.562
1.573AsnMet: 1.573 ± 0.516
1.966AsnAsn: 1.966 ± 0.407
3.382AsnPro: 3.382 ± 0.465
1.337AsnGln: 1.337 ± 0.304
2.517AsnArg: 2.517 ± 0.405
3.46AsnSer: 3.46 ± 0.613
2.989AsnThr: 2.989 ± 0.601
2.281AsnVal: 2.281 ± 0.48
0.786AsnTrp: 0.786 ± 0.225
2.281AsnTyr: 2.281 ± 0.465
0.0AsnXaa: 0.0 ± 0.0
Pro
5.269ProAla: 5.269 ± 0.686
0.708ProCys: 0.708 ± 0.218
4.326ProAsp: 4.326 ± 0.468
5.033ProGlu: 5.033 ± 0.65
2.595ProPhe: 2.595 ± 0.521
4.719ProGly: 4.719 ± 0.529
1.022ProHis: 1.022 ± 0.303
2.438ProIle: 2.438 ± 0.44
2.517ProLys: 2.517 ± 0.517
4.483ProLeu: 4.483 ± 0.651
1.022ProMet: 1.022 ± 0.329
2.831ProAsn: 2.831 ± 0.486
6.764ProPro: 6.764 ± 1.294
2.753ProGln: 2.753 ± 0.478
5.033ProArg: 5.033 ± 0.686
4.955ProSer: 4.955 ± 0.65
4.404ProThr: 4.404 ± 0.682
4.247ProVal: 4.247 ± 0.697
0.944ProTrp: 0.944 ± 0.306
1.888ProTyr: 1.888 ± 0.392
0.0ProXaa: 0.0 ± 0.0
Gln
3.539GlnAla: 3.539 ± 0.536
0.786GlnCys: 0.786 ± 0.269
2.202GlnAsp: 2.202 ± 0.393
3.382GlnGlu: 3.382 ± 0.496
1.101GlnPhe: 1.101 ± 0.293
1.966GlnGly: 1.966 ± 0.351
1.022GlnHis: 1.022 ± 0.213
1.258GlnIle: 1.258 ± 0.258
1.652GlnLys: 1.652 ± 0.354
4.168GlnLeu: 4.168 ± 0.509
0.944GlnMet: 0.944 ± 0.228
1.573GlnAsn: 1.573 ± 0.45
3.225GlnPro: 3.225 ± 0.382
3.146GlnGln: 3.146 ± 0.602
2.674GlnArg: 2.674 ± 0.476
3.46GlnSer: 3.46 ± 0.657
2.753GlnThr: 2.753 ± 0.512
2.202GlnVal: 2.202 ± 0.329
0.629GlnTrp: 0.629 ± 0.229
1.022GlnTyr: 1.022 ± 0.313
0.0GlnXaa: 0.0 ± 0.0
Arg
6.528ArgAla: 6.528 ± 1.076
1.573ArgCys: 1.573 ± 0.412
2.753ArgAsp: 2.753 ± 0.487
4.168ArgGlu: 4.168 ± 0.625
2.517ArgPhe: 2.517 ± 0.474
4.797ArgGly: 4.797 ± 0.649
2.281ArgHis: 2.281 ± 0.372
2.831ArgIle: 2.831 ± 0.475
2.989ArgLys: 2.989 ± 0.637
5.584ArgLeu: 5.584 ± 0.7
1.416ArgMet: 1.416 ± 0.283
3.46ArgAsn: 3.46 ± 0.492
5.112ArgPro: 5.112 ± 0.836
4.168ArgGln: 4.168 ± 0.498
7.55ArgArg: 7.55 ± 1.845
4.876ArgSer: 4.876 ± 0.665
2.989ArgThr: 2.989 ± 0.67
3.303ArgVal: 3.303 ± 0.643
1.101ArgTrp: 1.101 ± 0.213
1.494ArgTyr: 1.494 ± 0.331
0.0ArgXaa: 0.0 ± 0.0
Ser
4.64SerAla: 4.64 ± 0.529
1.416SerCys: 1.416 ± 0.338
3.067SerAsp: 3.067 ± 0.665
2.438SerGlu: 2.438 ± 0.38
2.674SerPhe: 2.674 ± 0.571
4.247SerGly: 4.247 ± 0.753
1.888SerHis: 1.888 ± 0.358
3.539SerIle: 3.539 ± 0.564
3.146SerLys: 3.146 ± 0.632
6.842SerLeu: 6.842 ± 0.752
1.888SerMet: 1.888 ± 0.407
2.91SerAsn: 2.91 ± 0.423
4.876SerPro: 4.876 ± 0.734
3.46SerGln: 3.46 ± 0.586
5.269SerArg: 5.269 ± 0.611
7.786SerSer: 7.786 ± 1.15
4.326SerThr: 4.326 ± 0.752
3.303SerVal: 3.303 ± 0.415
0.786SerTrp: 0.786 ± 0.349
2.517SerTyr: 2.517 ± 0.401
0.0SerXaa: 0.0 ± 0.0
Thr
4.168ThrAla: 4.168 ± 0.652
1.416ThrCys: 1.416 ± 0.355
2.438ThrAsp: 2.438 ± 0.543
3.696ThrGlu: 3.696 ± 0.509
2.831ThrPhe: 2.831 ± 0.56
3.382ThrGly: 3.382 ± 0.518
0.944ThrHis: 0.944 ± 0.223
3.067ThrIle: 3.067 ± 0.566
2.123ThrLys: 2.123 ± 0.492
6.449ThrLeu: 6.449 ± 0.738
1.809ThrMet: 1.809 ± 0.46
2.359ThrAsn: 2.359 ± 0.766
4.247ThrPro: 4.247 ± 0.578
1.966ThrGln: 1.966 ± 0.399
4.011ThrArg: 4.011 ± 0.745
4.168ThrSer: 4.168 ± 0.494
5.584ThrThr: 5.584 ± 0.911
4.011ThrVal: 4.011 ± 0.455
0.786ThrTrp: 0.786 ± 0.226
2.123ThrTyr: 2.123 ± 0.436
0.0ThrXaa: 0.0 ± 0.0
Val
4.876ValAla: 4.876 ± 0.544
1.101ValCys: 1.101 ± 0.395
3.775ValAsp: 3.775 ± 0.53
3.382ValGlu: 3.382 ± 0.636
1.73ValPhe: 1.73 ± 0.362
2.438ValGly: 2.438 ± 0.423
0.708ValHis: 0.708 ± 0.193
2.753ValIle: 2.753 ± 0.53
2.674ValLys: 2.674 ± 0.614
5.82ValLeu: 5.82 ± 0.692
1.809ValMet: 1.809 ± 0.426
2.989ValAsn: 2.989 ± 0.462
3.225ValPro: 3.225 ± 0.546
3.539ValGln: 3.539 ± 0.577
3.775ValArg: 3.775 ± 0.649
4.168ValSer: 4.168 ± 0.525
3.382ValThr: 3.382 ± 0.483
3.854ValVal: 3.854 ± 0.566
0.865ValTrp: 0.865 ± 0.241
2.359ValTyr: 2.359 ± 0.465
0.0ValXaa: 0.0 ± 0.0
Trp
0.629TrpAla: 0.629 ± 0.187
0.079TrpCys: 0.079 ± 0.088
1.101TrpAsp: 1.101 ± 0.405
0.708TrpGlu: 0.708 ± 0.213
0.472TrpPhe: 0.472 ± 0.167
0.786TrpGly: 0.786 ± 0.223
0.079TrpHis: 0.079 ± 0.081
0.551TrpIle: 0.551 ± 0.182
0.708TrpLys: 0.708 ± 0.248
1.101TrpLeu: 1.101 ± 0.278
0.393TrpMet: 0.393 ± 0.206
0.786TrpAsn: 0.786 ± 0.253
0.786TrpPro: 0.786 ± 0.259
0.629TrpGln: 0.629 ± 0.25
0.944TrpArg: 0.944 ± 0.265
1.337TrpSer: 1.337 ± 0.32
0.944TrpThr: 0.944 ± 0.247
0.315TrpVal: 0.315 ± 0.17
0.236TrpTrp: 0.236 ± 0.12
0.315TrpTyr: 0.315 ± 0.184
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.359TyrAla: 2.359 ± 0.459
0.944TyrCys: 0.944 ± 0.373
2.045TyrAsp: 2.045 ± 0.451
2.202TyrGlu: 2.202 ± 0.469
1.494TyrPhe: 1.494 ± 0.379
1.573TyrGly: 1.573 ± 0.414
0.944TyrHis: 0.944 ± 0.329
1.337TyrIle: 1.337 ± 0.278
1.652TyrLys: 1.652 ± 0.404
3.854TyrLeu: 3.854 ± 0.592
0.865TyrMet: 0.865 ± 0.242
1.18TyrAsn: 1.18 ± 0.343
1.573TyrPro: 1.573 ± 0.384
1.573TyrGln: 1.573 ± 0.4
2.202TyrArg: 2.202 ± 0.359
1.888TyrSer: 1.888 ± 0.389
2.045TyrThr: 2.045 ± 0.437
1.494TyrVal: 1.494 ± 0.338
0.393TyrTrp: 0.393 ± 0.141
1.258TyrTyr: 1.258 ± 0.357
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 46 proteins (12716 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski