Amino acid dipepetide frequency for Aedes camptorhynchus reo-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.85AlaAla: 4.85 ± 1.597
0.882AlaCys: 0.882 ± 0.227
1.543AlaAsp: 1.543 ± 0.608
1.984AlaGlu: 1.984 ± 0.176
3.527AlaPhe: 3.527 ± 1.074
2.425AlaGly: 2.425 ± 0.474
1.102AlaHis: 1.102 ± 0.157
2.646AlaIle: 2.646 ± 0.653
2.205AlaLys: 2.205 ± 0.524
4.85AlaLeu: 4.85 ± 1.467
1.323AlaMet: 1.323 ± 0.503
3.748AlaAsn: 3.748 ± 0.531
1.764AlaPro: 1.764 ± 0.71
0.882AlaGln: 0.882 ± 0.307
3.748AlaArg: 3.748 ± 0.572
4.189AlaSer: 4.189 ± 0.858
4.63AlaThr: 4.63 ± 0.544
4.63AlaVal: 4.63 ± 1.392
0.882AlaTrp: 0.882 ± 0.282
3.968AlaTyr: 3.968 ± 0.589
0.0AlaXaa: 0.0 ± 0.0
Cys
0.882CysAla: 0.882 ± 0.282
0.22CysCys: 0.22 ± 0.207
0.661CysAsp: 0.661 ± 0.307
0.882CysGlu: 0.882 ± 0.342
0.22CysPhe: 0.22 ± 0.18
0.441CysGly: 0.441 ± 0.227
0.0CysHis: 0.0 ± 0.0
0.882CysIle: 0.882 ± 0.377
0.441CysLys: 0.441 ± 0.233
0.661CysLeu: 0.661 ± 0.185
0.661CysMet: 0.661 ± 0.23
0.22CysAsn: 0.22 ± 0.184
0.441CysPro: 0.441 ± 0.386
0.22CysGln: 0.22 ± 0.184
0.441CysArg: 0.441 ± 0.218
1.102CysSer: 1.102 ± 0.3
0.882CysThr: 0.882 ± 0.365
0.441CysVal: 0.441 ± 0.386
0.22CysTrp: 0.22 ± 0.207
0.661CysTyr: 0.661 ± 0.388
0.0CysXaa: 0.0 ± 0.0
Asp
3.968AspAla: 3.968 ± 0.604
0.22AspCys: 0.22 ± 0.18
3.086AspAsp: 3.086 ± 0.778
3.748AspGlu: 3.748 ± 1.004
2.205AspPhe: 2.205 ± 0.758
2.866AspGly: 2.866 ± 0.814
1.323AspHis: 1.323 ± 0.704
5.511AspIle: 5.511 ± 0.966
2.425AspLys: 2.425 ± 0.951
5.291AspLeu: 5.291 ± 0.629
1.984AspMet: 1.984 ± 0.803
2.646AspAsn: 2.646 ± 0.292
2.866AspPro: 2.866 ± 0.524
1.543AspGln: 1.543 ± 0.548
0.882AspArg: 0.882 ± 0.377
4.63AspSer: 4.63 ± 0.715
3.527AspThr: 3.527 ± 0.972
6.173AspVal: 6.173 ± 1.034
0.22AspTrp: 0.22 ± 0.184
3.086AspTyr: 3.086 ± 0.975
0.0AspXaa: 0.0 ± 0.0
Glu
1.984GluAla: 1.984 ± 0.262
0.882GluCys: 0.882 ± 0.287
1.764GluAsp: 1.764 ± 0.432
3.307GluGlu: 3.307 ± 0.409
3.086GluPhe: 3.086 ± 0.383
1.984GluGly: 1.984 ± 0.832
1.102GluHis: 1.102 ± 0.461
5.291GluIle: 5.291 ± 0.397
2.425GluLys: 2.425 ± 0.515
4.409GluLeu: 4.409 ± 0.904
2.866GluMet: 2.866 ± 0.497
3.307GluAsn: 3.307 ± 0.694
1.323GluPro: 1.323 ± 0.482
1.543GluGln: 1.543 ± 0.25
4.409GluArg: 4.409 ± 0.184
2.866GluSer: 2.866 ± 0.333
2.205GluThr: 2.205 ± 0.629
2.646GluVal: 2.646 ± 0.504
0.22GluTrp: 0.22 ± 0.207
3.307GluTyr: 3.307 ± 0.897
0.0GluXaa: 0.0 ± 0.0
Phe
1.102PheAla: 1.102 ± 0.476
0.22PheCys: 0.22 ± 0.18
4.189PheAsp: 4.189 ± 0.683
1.984PheGlu: 1.984 ± 0.339
1.984PhePhe: 1.984 ± 0.92
1.984PheGly: 1.984 ± 0.525
0.882PheHis: 0.882 ± 0.282
2.425PheIle: 2.425 ± 0.943
3.086PheLys: 3.086 ± 0.76
2.425PheLeu: 2.425 ± 0.753
1.102PheMet: 1.102 ± 0.539
2.646PheAsn: 2.646 ± 0.823
1.543PhePro: 1.543 ± 0.508
1.984PheGln: 1.984 ± 0.532
2.866PheArg: 2.866 ± 0.841
3.968PheSer: 3.968 ± 0.646
3.086PheThr: 3.086 ± 0.693
2.646PheVal: 2.646 ± 0.769
0.0PheTrp: 0.0 ± 0.0
1.102PheTyr: 1.102 ± 0.535
0.0PheXaa: 0.0 ± 0.0
Gly
3.527GlyAla: 3.527 ± 0.53
0.441GlyCys: 0.441 ± 0.233
3.086GlyAsp: 3.086 ± 0.191
1.984GlyGlu: 1.984 ± 0.329
1.764GlyPhe: 1.764 ± 0.406
2.425GlyGly: 2.425 ± 0.566
1.102GlyHis: 1.102 ± 0.517
4.409GlyIle: 4.409 ± 0.916
3.086GlyLys: 3.086 ± 0.343
3.748GlyLeu: 3.748 ± 0.629
1.543GlyMet: 1.543 ± 0.234
2.205GlyAsn: 2.205 ± 0.663
0.882GlyPro: 0.882 ± 0.579
1.543GlyGln: 1.543 ± 0.428
1.102GlyArg: 1.102 ± 0.405
5.071GlySer: 5.071 ± 0.979
2.646GlyThr: 2.646 ± 0.737
3.748GlyVal: 3.748 ± 0.735
0.882GlyTrp: 0.882 ± 0.541
1.764GlyTyr: 1.764 ± 0.495
0.0GlyXaa: 0.0 ± 0.0
His
2.205HisAla: 2.205 ± 0.569
0.22HisCys: 0.22 ± 0.18
1.102HisAsp: 1.102 ± 0.231
0.882HisGlu: 0.882 ± 0.328
1.102HisPhe: 1.102 ± 0.757
0.882HisGly: 0.882 ± 0.466
0.441HisHis: 0.441 ± 0.171
1.764HisIle: 1.764 ± 0.651
1.984HisLys: 1.984 ± 0.546
3.527HisLeu: 3.527 ± 0.888
1.323HisMet: 1.323 ± 0.751
1.764HisAsn: 1.764 ± 0.539
0.661HisPro: 0.661 ± 0.343
0.661HisGln: 0.661 ± 0.307
0.0HisArg: 0.0 ± 0.0
1.102HisSer: 1.102 ± 0.435
1.764HisThr: 1.764 ± 0.206
1.984HisVal: 1.984 ± 0.262
0.22HisTrp: 0.22 ± 0.193
1.323HisTyr: 1.323 ± 0.531
0.0HisXaa: 0.0 ± 0.0
Ile
4.63IleAla: 4.63 ± 0.715
1.323IleCys: 1.323 ± 0.404
4.85IleAsp: 4.85 ± 0.844
5.291IleGlu: 5.291 ± 1.492
2.866IlePhe: 2.866 ± 1.028
3.307IleGly: 3.307 ± 0.536
1.764IleHis: 1.764 ± 0.51
5.291IleIle: 5.291 ± 0.797
4.409IleLys: 4.409 ± 0.44
6.614IleLeu: 6.614 ± 0.942
1.323IleMet: 1.323 ± 0.37
6.393IleAsn: 6.393 ± 0.95
3.968IlePro: 3.968 ± 0.447
2.866IleGln: 2.866 ± 1.046
5.952IleArg: 5.952 ± 0.855
6.834IleSer: 6.834 ± 0.495
4.85IleThr: 4.85 ± 0.974
4.409IleVal: 4.409 ± 1.277
0.22IleTrp: 0.22 ± 0.18
3.307IleTyr: 3.307 ± 0.861
0.0IleXaa: 0.0 ± 0.0
Lys
2.866LysAla: 2.866 ± 0.931
0.441LysCys: 0.441 ± 0.233
3.748LysAsp: 3.748 ± 0.76
1.984LysGlu: 1.984 ± 0.573
3.307LysPhe: 3.307 ± 0.706
1.323LysGly: 1.323 ± 0.435
1.323LysHis: 1.323 ± 0.336
6.834LysIle: 6.834 ± 0.867
3.307LysLys: 3.307 ± 0.887
4.189LysLeu: 4.189 ± 0.942
1.323LysMet: 1.323 ± 0.338
1.764LysAsn: 1.764 ± 0.34
1.102LysPro: 1.102 ± 0.231
2.205LysGln: 2.205 ± 0.436
2.646LysArg: 2.646 ± 0.661
3.968LysSer: 3.968 ± 0.681
3.086LysThr: 3.086 ± 1.041
3.748LysVal: 3.748 ± 0.574
0.882LysTrp: 0.882 ± 0.541
2.425LysTyr: 2.425 ± 1.185
0.0LysXaa: 0.0 ± 0.0
Leu
4.63LeuAla: 4.63 ± 0.864
1.102LeuCys: 1.102 ± 0.257
4.189LeuAsp: 4.189 ± 1.629
4.189LeuGlu: 4.189 ± 0.803
1.764LeuPhe: 1.764 ± 0.747
3.968LeuGly: 3.968 ± 0.959
2.425LeuHis: 2.425 ± 0.52
7.275LeuIle: 7.275 ± 0.764
6.834LeuLys: 6.834 ± 0.884
9.7LeuLeu: 9.7 ± 1.011
2.425LeuMet: 2.425 ± 0.715
6.614LeuAsn: 6.614 ± 0.921
3.968LeuPro: 3.968 ± 0.338
2.425LeuGln: 2.425 ± 0.977
5.732LeuArg: 5.732 ± 0.704
9.48LeuSer: 9.48 ± 2.068
7.716LeuThr: 7.716 ± 1.61
3.968LeuVal: 3.968 ± 0.629
0.661LeuTrp: 0.661 ± 0.23
3.527LeuTyr: 3.527 ± 0.736
0.0LeuXaa: 0.0 ± 0.0
Met
1.543MetAla: 1.543 ± 0.332
0.0MetCys: 0.0 ± 0.0
0.661MetAsp: 0.661 ± 0.3
1.543MetGlu: 1.543 ± 0.294
1.323MetPhe: 1.323 ± 0.641
1.764MetGly: 1.764 ± 0.495
0.441MetHis: 0.441 ± 0.227
2.425MetIle: 2.425 ± 1.063
2.425MetLys: 2.425 ± 0.279
3.748MetLeu: 3.748 ± 0.718
1.543MetMet: 1.543 ± 0.69
2.425MetAsn: 2.425 ± 0.459
0.441MetPro: 0.441 ± 0.227
1.323MetGln: 1.323 ± 0.554
1.984MetArg: 1.984 ± 0.343
3.307MetSer: 3.307 ± 0.533
1.323MetThr: 1.323 ± 0.613
1.102MetVal: 1.102 ± 0.328
0.882MetTrp: 0.882 ± 0.612
1.102MetTyr: 1.102 ± 0.231
0.0MetXaa: 0.0 ± 0.0
Asn
3.086AsnAla: 3.086 ± 0.992
0.882AsnCys: 0.882 ± 0.521
4.409AsnAsp: 4.409 ± 0.244
3.086AsnGlu: 3.086 ± 1.386
2.646AsnPhe: 2.646 ± 0.359
3.307AsnGly: 3.307 ± 0.712
0.441AsnHis: 0.441 ± 0.233
5.732AsnIle: 5.732 ± 1.432
2.205AsnLys: 2.205 ± 0.512
7.716AsnLeu: 7.716 ± 1.93
1.102AsnMet: 1.102 ± 0.386
2.425AsnAsn: 2.425 ± 0.377
2.425AsnPro: 2.425 ± 0.377
1.323AsnGln: 1.323 ± 0.338
4.189AsnArg: 4.189 ± 0.72
5.291AsnSer: 5.291 ± 0.331
3.748AsnThr: 3.748 ± 0.77
3.748AsnVal: 3.748 ± 0.718
0.0AsnTrp: 0.0 ± 0.0
3.086AsnTyr: 3.086 ± 0.975
0.0AsnXaa: 0.0 ± 0.0
Pro
1.984ProAla: 1.984 ± 0.445
1.102ProCys: 1.102 ± 0.172
2.205ProAsp: 2.205 ± 0.816
2.425ProGlu: 2.425 ± 0.214
0.441ProPhe: 0.441 ± 0.361
1.984ProGly: 1.984 ± 0.775
0.661ProHis: 0.661 ± 0.185
3.527ProIle: 3.527 ± 0.626
1.102ProLys: 1.102 ± 0.157
3.307ProLeu: 3.307 ± 0.674
1.323ProMet: 1.323 ± 0.275
2.425ProAsn: 2.425 ± 0.673
0.882ProPro: 0.882 ± 0.533
0.882ProGln: 0.882 ± 0.564
1.543ProArg: 1.543 ± 0.304
3.086ProSer: 3.086 ± 0.361
2.866ProThr: 2.866 ± 0.704
3.307ProVal: 3.307 ± 1.325
0.661ProTrp: 0.661 ± 0.185
2.205ProTyr: 2.205 ± 0.462
0.0ProXaa: 0.0 ± 0.0
Gln
1.764GlnAla: 1.764 ± 0.56
0.661GlnCys: 0.661 ± 0.388
1.323GlnAsp: 1.323 ± 0.604
1.102GlnGlu: 1.102 ± 0.517
2.425GlnPhe: 2.425 ± 0.77
1.102GlnGly: 1.102 ± 0.231
1.102GlnHis: 1.102 ± 0.445
1.543GlnIle: 1.543 ± 0.304
0.882GlnLys: 0.882 ± 0.377
3.527GlnLeu: 3.527 ± 0.545
0.661GlnMet: 0.661 ± 0.393
1.984GlnAsn: 1.984 ± 1.158
0.441GlnPro: 0.441 ± 0.233
0.661GlnGln: 0.661 ± 0.385
1.764GlnArg: 1.764 ± 0.18
2.205GlnSer: 2.205 ± 0.067
2.425GlnThr: 2.425 ± 0.77
2.205GlnVal: 2.205 ± 0.42
0.22GlnTrp: 0.22 ± 0.207
0.882GlnTyr: 0.882 ± 0.282
0.0GlnXaa: 0.0 ± 0.0
Arg
2.205ArgAla: 2.205 ± 0.617
0.441ArgCys: 0.441 ± 0.227
3.527ArgAsp: 3.527 ± 0.51
2.205ArgGlu: 2.205 ± 0.572
3.968ArgPhe: 3.968 ± 0.707
1.984ArgGly: 1.984 ± 0.151
2.205ArgHis: 2.205 ± 0.356
5.291ArgIle: 5.291 ± 0.728
2.205ArgLys: 2.205 ± 0.334
5.071ArgLeu: 5.071 ± 0.679
1.764ArgMet: 1.764 ± 0.446
3.968ArgAsn: 3.968 ± 0.645
2.866ArgPro: 2.866 ± 0.308
0.661ArgGln: 0.661 ± 0.579
3.748ArgArg: 3.748 ± 0.943
5.291ArgSer: 5.291 ± 0.409
1.984ArgThr: 1.984 ± 0.525
3.307ArgVal: 3.307 ± 1.077
0.22ArgTrp: 0.22 ± 0.193
2.205ArgTyr: 2.205 ± 0.26
0.0ArgXaa: 0.0 ± 0.0
Ser
4.409SerAla: 4.409 ± 0.494
0.661SerCys: 0.661 ± 0.399
5.291SerAsp: 5.291 ± 1.275
5.511SerGlu: 5.511 ± 0.462
3.086SerPhe: 3.086 ± 0.343
4.85SerGly: 4.85 ± 0.583
3.527SerHis: 3.527 ± 0.722
7.937SerIle: 7.937 ± 1.279
4.409SerLys: 4.409 ± 0.569
7.275SerLeu: 7.275 ± 1.131
2.866SerMet: 2.866 ± 0.596
4.189SerAsn: 4.189 ± 1.374
3.307SerPro: 3.307 ± 1.03
2.205SerGln: 2.205 ± 0.694
4.189SerArg: 4.189 ± 0.496
8.157SerSer: 8.157 ± 0.801
5.732SerThr: 5.732 ± 0.415
7.275SerVal: 7.275 ± 1.073
0.661SerTrp: 0.661 ± 0.307
2.205SerTyr: 2.205 ± 0.666
0.0SerXaa: 0.0 ± 0.0
Thr
4.85ThrAla: 4.85 ± 0.828
0.22ThrCys: 0.22 ± 0.193
3.527ThrAsp: 3.527 ± 0.742
2.866ThrGlu: 2.866 ± 1.063
2.646ThrPhe: 2.646 ± 0.196
3.527ThrGly: 3.527 ± 0.418
1.764ThrHis: 1.764 ± 0.276
4.85ThrIle: 4.85 ± 0.696
3.086ThrLys: 3.086 ± 0.656
5.071ThrLeu: 5.071 ± 0.717
1.764ThrMet: 1.764 ± 0.432
3.748ThrAsn: 3.748 ± 0.895
3.968ThrPro: 3.968 ± 0.937
3.307ThrGln: 3.307 ± 0.461
2.646ThrArg: 2.646 ± 0.964
5.952ThrSer: 5.952 ± 0.83
5.291ThrThr: 5.291 ± 1.817
4.63ThrVal: 4.63 ± 1.213
0.441ThrTrp: 0.441 ± 0.218
1.764ThrTyr: 1.764 ± 0.446
0.0ThrXaa: 0.0 ± 0.0
Val
3.086ValAla: 3.086 ± 0.719
0.441ValCys: 0.441 ± 0.386
4.85ValAsp: 4.85 ± 0.77
2.866ValGlu: 2.866 ± 1.215
2.425ValPhe: 2.425 ± 0.395
2.646ValGly: 2.646 ± 0.867
1.764ValHis: 1.764 ± 0.266
4.63ValIle: 4.63 ± 0.685
3.086ValLys: 3.086 ± 0.653
5.952ValLeu: 5.952 ± 1.081
1.984ValMet: 1.984 ± 0.151
5.952ValAsn: 5.952 ± 0.808
3.968ValPro: 3.968 ± 1.187
1.102ValGln: 1.102 ± 0.414
4.85ValArg: 4.85 ± 0.537
7.275ValSer: 7.275 ± 1.635
4.63ValThr: 4.63 ± 0.669
3.748ValVal: 3.748 ± 0.364
0.441ValTrp: 0.441 ± 0.233
1.102ValTyr: 1.102 ± 0.231
0.0ValXaa: 0.0 ± 0.0
Trp
0.22TrpAla: 0.22 ± 0.184
0.22TrpCys: 0.22 ± 0.193
0.441TrpAsp: 0.441 ± 0.171
0.0TrpGlu: 0.0 ± 0.0
0.22TrpPhe: 0.22 ± 0.207
0.22TrpGly: 0.22 ± 0.207
0.441TrpHis: 0.441 ± 0.252
0.882TrpIle: 0.882 ± 0.364
0.661TrpLys: 0.661 ± 0.386
0.661TrpLeu: 0.661 ± 0.185
0.22TrpMet: 0.22 ± 0.184
0.441TrpAsn: 0.441 ± 0.369
0.22TrpPro: 0.22 ± 0.184
0.0TrpGln: 0.0 ± 0.0
0.661TrpArg: 0.661 ± 0.357
0.882TrpSer: 0.882 ± 0.307
0.22TrpThr: 0.22 ± 0.18
0.441TrpVal: 0.441 ± 0.386
0.0TrpTrp: 0.0 ± 0.0
0.882TrpTyr: 0.882 ± 0.227
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.984TyrAla: 1.984 ± 0.151
0.0TyrCys: 0.0 ± 0.0
3.968TyrAsp: 3.968 ± 0.802
3.086TyrGlu: 3.086 ± 0.426
0.22TyrPhe: 0.22 ± 0.207
3.968TyrGly: 3.968 ± 0.367
1.102TyrHis: 1.102 ± 0.591
1.323TyrIle: 1.323 ± 0.604
2.205TyrLys: 2.205 ± 0.815
4.85TyrLeu: 4.85 ± 0.354
1.984TyrMet: 1.984 ± 0.533
1.984TyrAsn: 1.984 ± 0.379
0.882TyrPro: 0.882 ± 0.464
1.543TyrGln: 1.543 ± 0.234
1.764TyrArg: 1.764 ± 0.625
3.086TyrSer: 3.086 ± 0.561
3.307TyrThr: 3.307 ± 0.977
2.646TyrVal: 2.646 ± 0.55
0.0TyrTrp: 0.0 ± 0.0
3.527TyrTyr: 3.527 ± 0.958
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski