Amino acid dipepetide frequency for Capybara microvirus Cap1_SP_52

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.232AlaAla: 2.232 ± 1.062
0.558AlaCys: 0.558 ± 0.929
2.232AlaAsp: 2.232 ± 1.062
1.116AlaGlu: 1.116 ± 1.161
2.232AlaPhe: 2.232 ± 0.982
2.79AlaGly: 2.79 ± 1.365
1.116AlaHis: 1.116 ± 0.978
2.79AlaIle: 2.79 ± 1.096
2.232AlaLys: 2.232 ± 0.373
5.58AlaLeu: 5.58 ± 0.95
1.674AlaMet: 1.674 ± 1.05
6.138AlaAsn: 6.138 ± 1.455
2.79AlaPro: 2.79 ± 0.97
3.348AlaGln: 3.348 ± 2.758
2.79AlaArg: 2.79 ± 1.559
5.022AlaSer: 5.022 ± 1.183
3.906AlaThr: 3.906 ± 1.68
2.232AlaVal: 2.232 ± 0.624
0.0AlaTrp: 0.0 ± 0.0
2.79AlaTyr: 2.79 ± 0.522
0.0AlaXaa: 0.0 ± 0.0
Cys
0.558CysAla: 0.558 ± 0.495
0.0CysCys: 0.0 ± 0.0
1.116CysAsp: 1.116 ± 0.978
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.116CysGly: 1.116 ± 0.463
0.558CysHis: 0.558 ± 0.368
1.674CysIle: 1.674 ± 0.886
0.558CysLys: 0.558 ± 0.495
1.674CysLeu: 1.674 ± 0.886
0.0CysMet: 0.0 ± 0.0
0.558CysAsn: 0.558 ± 0.368
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.558CysSer: 0.558 ± 0.929
1.116CysThr: 1.116 ± 0.463
1.116CysVal: 1.116 ± 0.788
0.0CysTrp: 0.0 ± 0.0
1.116CysTyr: 1.116 ± 0.634
0.0CysXaa: 0.0 ± 0.0
Asp
3.348AspAla: 3.348 ± 1.157
0.0AspCys: 0.0 ± 0.0
3.348AspAsp: 3.348 ± 2.533
1.674AspGlu: 1.674 ± 0.83
3.348AspPhe: 3.348 ± 1.348
2.232AspGly: 2.232 ± 0.982
0.0AspHis: 0.0 ± 0.0
5.58AspIle: 5.58 ± 2.089
3.906AspLys: 3.906 ± 1.544
7.812AspLeu: 7.812 ± 1.802
1.116AspMet: 1.116 ± 0.531
5.022AspAsn: 5.022 ± 1.039
1.116AspPro: 1.116 ± 0.558
1.116AspGln: 1.116 ± 0.735
1.116AspArg: 1.116 ± 1.161
6.138AspSer: 6.138 ± 1.432
4.464AspThr: 4.464 ± 1.207
2.232AspVal: 2.232 ± 0.982
0.558AspTrp: 0.558 ± 0.495
6.138AspTyr: 6.138 ± 0.885
0.0AspXaa: 0.0 ± 0.0
Glu
2.232GluAla: 2.232 ± 2.322
0.0GluCys: 0.0 ± 0.0
2.232GluAsp: 2.232 ± 1.577
0.0GluGlu: 0.0 ± 0.0
4.464GluPhe: 4.464 ± 1.963
1.116GluGly: 1.116 ± 0.531
0.558GluHis: 0.558 ± 0.368
2.79GluIle: 2.79 ± 1.423
2.232GluLys: 2.232 ± 0.373
4.464GluLeu: 4.464 ± 1.595
0.0GluMet: 0.0 ± 0.0
4.464GluAsn: 4.464 ± 1.248
1.116GluPro: 1.116 ± 0.735
5.022GluGln: 5.022 ± 1.464
2.232GluArg: 2.232 ± 0.926
3.906GluSer: 3.906 ± 2.499
6.696GluThr: 6.696 ± 2.476
2.79GluVal: 2.79 ± 1.324
0.0GluTrp: 0.0 ± 0.0
3.348GluTyr: 3.348 ± 0.947
0.0GluXaa: 0.0 ± 0.0
Phe
4.464PheAla: 4.464 ± 1.963
0.558PheCys: 0.558 ± 0.495
7.254PheAsp: 7.254 ± 1.844
3.348PheGlu: 3.348 ± 1.568
5.58PhePhe: 5.58 ± 0.831
3.348PheGly: 3.348 ± 2.205
1.674PheHis: 1.674 ± 1.091
1.116PheIle: 1.116 ± 0.872
4.464PheLys: 4.464 ± 0.747
4.464PheLeu: 4.464 ± 0.88
0.0PheMet: 0.0 ± 0.0
5.022PheAsn: 5.022 ± 1.458
2.232PhePro: 2.232 ± 1.47
1.116PheGln: 1.116 ± 0.634
4.464PheArg: 4.464 ± 1.682
3.906PheSer: 3.906 ± 1.627
1.116PheThr: 1.116 ± 0.463
2.232PheVal: 2.232 ± 1.168
1.116PheTrp: 1.116 ± 0.991
2.232PheTyr: 2.232 ± 1.981
0.0PheXaa: 0.0 ± 0.0
Gly
1.116GlyAla: 1.116 ± 0.531
0.558GlyCys: 0.558 ± 0.368
1.116GlyAsp: 1.116 ± 0.735
3.906GlyGlu: 3.906 ± 1.775
3.348GlyPhe: 3.348 ± 1.662
2.232GlyGly: 2.232 ± 1.612
0.558GlyHis: 0.558 ± 0.495
5.58GlyIle: 5.58 ± 1.389
2.232GlyLys: 2.232 ± 0.624
2.79GlyLeu: 2.79 ± 0.706
1.116GlyMet: 1.116 ± 0.531
2.232GlyAsn: 2.232 ± 1.025
1.116GlyPro: 1.116 ± 0.558
1.674GlyGln: 1.674 ± 1.026
1.116GlyArg: 1.116 ± 0.463
3.348GlySer: 3.348 ± 1.662
3.348GlyThr: 3.348 ± 0.897
1.674GlyVal: 1.674 ± 1.103
0.0GlyTrp: 0.0 ± 0.0
6.138GlyTyr: 6.138 ± 2.307
0.0GlyXaa: 0.0 ± 0.0
His
2.232HisAla: 2.232 ± 0.982
1.116HisCys: 1.116 ± 0.991
0.558HisAsp: 0.558 ± 0.368
1.116HisGlu: 1.116 ± 0.978
0.558HisPhe: 0.558 ± 0.368
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.232HisIle: 2.232 ± 0.926
1.116HisLys: 1.116 ± 0.463
1.674HisLeu: 1.674 ± 0.705
0.0HisMet: 0.0 ± 0.0
2.232HisAsn: 2.232 ± 1.025
1.674HisPro: 1.674 ± 1.155
0.0HisGln: 0.0 ± 0.0
1.116HisArg: 1.116 ± 0.634
2.79HisSer: 2.79 ± 1.086
0.558HisThr: 0.558 ± 0.495
1.116HisVal: 1.116 ± 0.463
0.0HisTrp: 0.0 ± 0.0
1.116HisTyr: 1.116 ± 0.991
0.0HisXaa: 0.0 ± 0.0
Ile
1.674IleAla: 1.674 ± 1.596
0.0IleCys: 0.0 ± 0.0
3.906IleAsp: 3.906 ± 1.079
5.58IleGlu: 5.58 ± 2.052
2.79IlePhe: 2.79 ± 1.324
5.022IleGly: 5.022 ± 1.734
0.0IleHis: 0.0 ± 0.0
5.022IleIle: 5.022 ± 2.603
5.022IleLys: 5.022 ± 1.101
2.232IleLeu: 2.232 ± 1.562
1.674IleMet: 1.674 ± 0.682
7.254IleAsn: 7.254 ± 1.193
2.232IlePro: 2.232 ± 0.926
2.79IleGln: 2.79 ± 1.53
3.348IleArg: 3.348 ± 1.607
5.022IleSer: 5.022 ± 0.762
2.232IleThr: 2.232 ± 0.83
1.674IleVal: 1.674 ± 0.963
0.558IleTrp: 0.558 ± 0.495
4.464IleTyr: 4.464 ± 1.476
0.0IleXaa: 0.0 ± 0.0
Lys
3.348LysAla: 3.348 ± 1.348
1.674LysCys: 1.674 ± 0.674
5.58LysAsp: 5.58 ± 1.045
2.79LysGlu: 2.79 ± 1.231
2.79LysPhe: 2.79 ± 1.429
3.348LysGly: 3.348 ± 1.152
1.674LysHis: 1.674 ± 1.155
3.906LysIle: 3.906 ± 0.605
3.906LysLys: 3.906 ± 1.783
7.254LysLeu: 7.254 ± 2.139
0.558LysMet: 0.558 ± 0.581
1.674LysAsn: 1.674 ± 1.096
1.674LysPro: 1.674 ± 0.886
2.79LysGln: 2.79 ± 1.225
1.116LysArg: 1.116 ± 0.833
3.348LysSer: 3.348 ± 1.326
4.464LysThr: 4.464 ± 0.864
2.79LysVal: 2.79 ± 0.522
0.0LysTrp: 0.0 ± 0.0
1.674LysTyr: 1.674 ± 0.83
0.0LysXaa: 0.0 ± 0.0
Leu
7.812LeuAla: 7.812 ± 2.513
1.116LeuCys: 1.116 ± 0.788
6.138LeuAsp: 6.138 ± 2.106
5.022LeuGlu: 5.022 ± 1.782
5.58LeuPhe: 5.58 ± 1.182
6.138LeuGly: 6.138 ± 0.915
0.558LeuHis: 0.558 ± 0.632
4.464LeuIle: 4.464 ± 1.308
6.696LeuLys: 6.696 ± 2.179
8.371LeuLeu: 8.371 ± 1.179
1.116LeuMet: 1.116 ± 1.198
4.464LeuAsn: 4.464 ± 1.257
5.58LeuPro: 5.58 ± 1.138
3.906LeuGln: 3.906 ± 1.127
3.348LeuArg: 3.348 ± 0.653
9.487LeuSer: 9.487 ± 1.424
3.906LeuThr: 3.906 ± 0.583
3.906LeuVal: 3.906 ± 1.28
0.0LeuTrp: 0.0 ± 0.0
5.58LeuTyr: 5.58 ± 2.09
0.0LeuXaa: 0.0 ± 0.0
Met
1.116MetAla: 1.116 ± 0.531
0.558MetCys: 0.558 ± 0.368
0.0MetAsp: 0.0 ± 0.0
0.558MetGlu: 0.558 ± 0.368
1.116MetPhe: 1.116 ± 0.558
0.558MetGly: 0.558 ± 0.581
0.558MetHis: 0.558 ± 0.368
0.0MetIle: 0.0 ± 0.0
2.232MetLys: 2.232 ± 1.895
2.79MetLeu: 2.79 ± 0.818
1.116MetMet: 1.116 ± 0.531
0.558MetAsn: 0.558 ± 0.581
1.674MetPro: 1.674 ± 1.103
2.232MetGln: 2.232 ± 1.612
1.674MetArg: 1.674 ± 0.881
1.116MetSer: 1.116 ± 0.463
0.0MetThr: 0.0 ± 0.0
0.558MetVal: 0.558 ± 0.632
0.0MetTrp: 0.0 ± 0.0
1.116MetTyr: 1.116 ± 0.788
0.0MetXaa: 0.0 ± 0.0
Asn
5.022AsnAla: 5.022 ± 1.821
1.116AsnCys: 1.116 ± 0.634
3.348AsnAsp: 3.348 ± 0.653
5.022AsnGlu: 5.022 ± 1.469
6.696AsnPhe: 6.696 ± 1.642
3.348AsnGly: 3.348 ± 0.629
1.674AsnHis: 1.674 ± 0.674
6.696AsnIle: 6.696 ± 1.712
2.79AsnLys: 2.79 ± 1.464
8.371AsnLeu: 8.371 ± 1.587
1.116AsnMet: 1.116 ± 0.463
5.022AsnAsn: 5.022 ± 1.623
3.906AsnPro: 3.906 ± 2.014
4.464AsnGln: 4.464 ± 2.879
3.348AsnArg: 3.348 ± 1.94
5.022AsnSer: 5.022 ± 1.804
3.906AsnThr: 3.906 ± 1.584
5.58AsnVal: 5.58 ± 0.957
0.558AsnTrp: 0.558 ± 0.368
6.138AsnTyr: 6.138 ± 2.453
0.0AsnXaa: 0.0 ± 0.0
Pro
2.232ProAla: 2.232 ± 0.991
0.558ProCys: 0.558 ± 0.929
2.79ProAsp: 2.79 ± 1.137
2.232ProGlu: 2.232 ± 0.991
2.232ProPhe: 2.232 ± 1.003
1.674ProGly: 1.674 ± 0.674
1.116ProHis: 1.116 ± 0.463
3.348ProIle: 3.348 ± 1.671
4.464ProLys: 4.464 ± 2.243
3.348ProLeu: 3.348 ± 0.653
1.116ProMet: 1.116 ± 0.558
4.464ProAsn: 4.464 ± 1.504
0.558ProPro: 0.558 ± 0.495
4.464ProGln: 4.464 ± 0.747
1.116ProArg: 1.116 ± 0.735
2.232ProSer: 2.232 ± 1.47
0.558ProThr: 0.558 ± 0.368
0.558ProVal: 0.558 ± 0.368
0.0ProTrp: 0.0 ± 0.0
3.348ProTyr: 3.348 ± 0.653
0.0ProXaa: 0.0 ± 0.0
Gln
2.232GlnAla: 2.232 ± 0.8
1.116GlnCys: 1.116 ± 0.463
2.79GlnAsp: 2.79 ± 1.052
1.116GlnGlu: 1.116 ± 0.531
5.022GlnPhe: 5.022 ± 2.337
0.558GlnGly: 0.558 ± 0.581
1.116GlnHis: 1.116 ± 0.531
1.674GlnIle: 1.674 ± 1.026
1.116GlnLys: 1.116 ± 0.463
3.906GlnLeu: 3.906 ± 0.863
1.116GlnMet: 1.116 ± 0.558
5.022GlnAsn: 5.022 ± 0.852
1.116GlnPro: 1.116 ± 0.463
2.79GlnGln: 2.79 ± 0.818
2.232GlnArg: 2.232 ± 0.8
5.022GlnSer: 5.022 ± 1.673
3.906GlnThr: 3.906 ± 1.232
5.022GlnVal: 5.022 ± 1.393
1.674GlnTrp: 1.674 ± 1.05
1.674GlnTyr: 1.674 ± 1.103
0.0GlnXaa: 0.0 ± 0.0
Arg
0.558ArgAla: 0.558 ± 0.368
0.0ArgCys: 0.0 ± 0.0
3.348ArgAsp: 3.348 ± 1.335
5.022ArgGlu: 5.022 ± 2.276
2.232ArgPhe: 2.232 ± 1.316
1.116ArgGly: 1.116 ± 0.833
1.116ArgHis: 1.116 ± 0.531
2.232ArgIle: 2.232 ± 0.991
2.232ArgLys: 2.232 ± 1.043
3.348ArgLeu: 3.348 ± 0.629
0.558ArgMet: 0.558 ± 0.581
5.58ArgAsn: 5.58 ± 1.344
3.906ArgPro: 3.906 ± 0.583
3.348ArgGln: 3.348 ± 1.232
1.674ArgArg: 1.674 ± 1.091
1.674ArgSer: 1.674 ± 1.34
2.79ArgThr: 2.79 ± 0.522
2.232ArgVal: 2.232 ± 1.052
0.558ArgTrp: 0.558 ± 0.495
2.79ArgTyr: 2.79 ± 1.318
0.0ArgXaa: 0.0 ± 0.0
Ser
5.022SerAla: 5.022 ± 1.734
1.674SerCys: 1.674 ± 0.886
3.906SerAsp: 3.906 ± 0.922
2.79SerGlu: 2.79 ± 0.754
5.58SerPhe: 5.58 ± 1.961
2.232SerGly: 2.232 ± 0.991
2.79SerHis: 2.79 ± 1.096
5.022SerIle: 5.022 ± 1.678
3.348SerLys: 3.348 ± 1.435
7.812SerLeu: 7.812 ± 1.661
2.232SerMet: 2.232 ± 1.047
7.254SerAsn: 7.254 ± 2.674
3.906SerPro: 3.906 ± 0.863
3.906SerGln: 3.906 ± 1.706
3.348SerArg: 3.348 ± 1.545
7.254SerSer: 7.254 ± 2.082
2.232SerThr: 2.232 ± 1.062
3.348SerVal: 3.348 ± 1.038
0.558SerTrp: 0.558 ± 0.368
3.906SerTyr: 3.906 ± 1.319
0.0SerXaa: 0.0 ± 0.0
Thr
4.464ThrAla: 4.464 ± 1.629
0.0ThrCys: 0.0 ± 0.0
2.79ThrAsp: 2.79 ± 0.97
3.348ThrGlu: 3.348 ± 1.592
0.558ThrPhe: 0.558 ± 0.368
1.116ThrGly: 1.116 ± 0.735
1.116ThrHis: 1.116 ± 0.463
3.906ThrIle: 3.906 ± 0.857
2.232ThrLys: 2.232 ± 1.225
5.58ThrLeu: 5.58 ± 1.788
1.116ThrMet: 1.116 ± 0.558
5.022ThrAsn: 5.022 ± 2.796
2.232ThrPro: 2.232 ± 0.991
3.906ThrGln: 3.906 ± 1.013
3.348ThrArg: 3.348 ± 1.251
3.348ThrSer: 3.348 ± 1.261
6.138ThrThr: 6.138 ± 1.696
1.116ThrVal: 1.116 ± 0.463
1.674ThrTrp: 1.674 ± 1.05
2.232ThrTyr: 2.232 ± 1.358
0.0ThrXaa: 0.0 ± 0.0
Val
1.674ValAla: 1.674 ± 0.674
0.558ValCys: 0.558 ± 0.495
3.906ValAsp: 3.906 ± 1.234
2.232ValGlu: 2.232 ± 0.373
2.232ValPhe: 2.232 ± 0.855
3.906ValGly: 3.906 ± 0.94
1.116ValHis: 1.116 ± 0.991
2.232ValIle: 2.232 ± 2.03
2.232ValLys: 2.232 ± 0.8
2.232ValLeu: 2.232 ± 0.768
2.232ValMet: 2.232 ± 0.926
6.138ValAsn: 6.138 ± 1.88
3.348ValPro: 3.348 ± 1.348
0.558ValGln: 0.558 ± 0.368
2.79ValArg: 2.79 ± 0.973
3.348ValSer: 3.348 ± 0.629
2.232ValThr: 2.232 ± 0.768
1.116ValVal: 1.116 ± 0.872
0.0ValTrp: 0.0 ± 0.0
0.558ValTyr: 0.558 ± 0.368
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.558TrpCys: 0.558 ± 0.495
1.116TrpAsp: 1.116 ± 0.872
0.558TrpGlu: 0.558 ± 0.368
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.558TrpHis: 0.558 ± 0.495
0.558TrpIle: 0.558 ± 0.368
0.0TrpLys: 0.0 ± 0.0
1.116TrpLeu: 1.116 ± 0.991
0.0TrpMet: 0.0 ± 0.0
1.116TrpAsn: 1.116 ± 1.161
0.558TrpPro: 0.558 ± 0.495
1.116TrpGln: 1.116 ± 0.558
0.0TrpArg: 0.0 ± 0.0
1.116TrpSer: 1.116 ± 0.531
0.0TrpThr: 0.0 ± 0.0
0.558TrpVal: 0.558 ± 0.368
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.232TyrAla: 2.232 ± 0.373
0.0TyrCys: 0.0 ± 0.0
2.79TyrAsp: 2.79 ± 1.324
2.232TyrGlu: 2.232 ± 0.926
3.348TyrPhe: 3.348 ± 1.299
3.348TyrGly: 3.348 ± 1.348
3.348TyrHis: 3.348 ± 1.39
1.674TyrIle: 1.674 ± 0.677
3.348TyrLys: 3.348 ± 1.568
8.371TyrLeu: 8.371 ± 1.763
1.116TyrMet: 1.116 ± 0.667
3.906TyrAsn: 3.906 ± 0.57
1.674TyrPro: 1.674 ± 0.677
1.674TyrGln: 1.674 ± 0.886
6.138TyrArg: 6.138 ± 2.239
4.464TyrSer: 4.464 ± 1.15
1.674TyrThr: 1.674 ± 0.705
2.79TyrVal: 2.79 ± 0.754
1.674TyrTrp: 1.674 ± 0.83
2.232TyrTyr: 2.232 ± 0.624
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1793 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski