Amino acid dipepetide frequency for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.501AlaAla: 7.501 ± 0.034	1.391AlaCys: 1.391 ± 0.008	3.02AlaAsp: 3.02 ± 0.012	5.091AlaGlu: 5.091 ± 0.02	2.497AlaPhe: 2.497 ± 0.011	5.071AlaGly: 5.071 ± 0.023	1.6AlaHis: 1.6 ± 0.008	2.517AlaIle: 2.517 ± 0.009	3.354AlaLys: 3.354 ± 0.015	7.41AlaLeu: 7.41 ± 0.022	1.39AlaMet: 1.39 ± 0.008	1.919AlaAsn: 1.919 ± 0.009	4.764AlaPro: 4.764 ± 0.028	3.528AlaGln: 3.528 ± 0.016	3.985AlaArg: 3.985 ± 0.015	6.225AlaSer: 6.225 ± 0.021	3.56AlaThr: 3.56 ± 0.014	4.791AlaVal: 4.791 ± 0.016	0.813AlaTrp: 0.813 ± 0.007	1.44AlaTyr: 1.44 ± 0.008	0.005AlaXaa: 0.005 ± 0.0
Cys	1.247CysAla: 1.247 ± 0.008	0.587CysCys: 0.587 ± 0.006	0.977CysAsp: 0.977 ± 0.008	1.241CysGlu: 1.241 ± 0.009	0.769CysPhe: 0.769 ± 0.007	1.66CysGly: 1.66 ± 0.015	0.637CysHis: 0.637 ± 0.006	0.866CysIle: 0.866 ± 0.007	1.068CysLys: 1.068 ± 0.007	2.122CysLeu: 2.122 ± 0.01	0.383CysMet: 0.383 ± 0.003	0.732CysAsn: 0.732 ± 0.007	1.424CysPro: 1.424 ± 0.011	1.052CysGln: 1.052 ± 0.009	1.292CysArg: 1.292 ± 0.008	1.953CysSer: 1.953 ± 0.011	1.034CysThr: 1.034 ± 0.007	1.253CysVal: 1.253 ± 0.008	0.28CysTrp: 0.28 ± 0.003	0.518CysTyr: 0.518 ± 0.005	0.002CysXaa: 0.002 ± 0.0
Asp	2.93AspAla: 2.93 ± 0.011	1.021AspCys: 1.021 ± 0.008	2.7AspAsp: 2.7 ± 0.014	3.507AspGlu: 3.507 ± 0.014	2.07AspPhe: 2.07 ± 0.009	3.337AspGly: 3.337 ± 0.016	1.134AspHis: 1.134 ± 0.007	2.416AspIle: 2.416 ± 0.012	2.461AspLys: 2.461 ± 0.01	5.082AspLeu: 5.082 ± 0.016	1.05AspMet: 1.05 ± 0.006	1.534AspAsn: 1.534 ± 0.008	3.023AspPro: 3.023 ± 0.012	1.87AspGln: 1.87 ± 0.008	2.476AspArg: 2.476 ± 0.012	4.348AspSer: 4.348 ± 0.017	2.404AspThr: 2.404 ± 0.01	3.075AspVal: 3.075 ± 0.016	0.62AspTrp: 0.62 ± 0.005	1.39AspTyr: 1.39 ± 0.009	0.004AspXaa: 0.004 ± 0.0
Glu	5.534GluAla: 5.534 ± 0.021	1.407GluCys: 1.407 ± 0.015	4.542GluAsp: 4.542 ± 0.016	8.25GluGlu: 8.25 ± 0.035	1.979GluPhe: 1.979 ± 0.01	4.393GluGly: 4.393 ± 0.018	1.53GluHis: 1.53 ± 0.009	3.052GluIle: 3.052 ± 0.013	5.535GluLys: 5.535 ± 0.028	6.705GluLeu: 6.705 ± 0.026	1.66GluMet: 1.66 ± 0.008	3.106GluAsn: 3.106 ± 0.014	3.506GluPro: 3.506 ± 0.016	3.34GluGln: 3.34 ± 0.017	4.325GluArg: 4.325 ± 0.02	4.601GluSer: 4.601 ± 0.018	3.455GluThr: 3.455 ± 0.015	4.264GluVal: 4.264 ± 0.018	0.679GluTrp: 0.679 ± 0.005	1.478GluTyr: 1.478 ± 0.008	0.005GluXaa: 0.005 ± 0.0
Phe	1.891PheAla: 1.891 ± 0.01	0.858PheCys: 0.858 ± 0.006	1.581PheAsp: 1.581 ± 0.008	1.942PheGlu: 1.942 ± 0.009	1.389PhePhe: 1.389 ± 0.008	2.085PheGly: 2.085 ± 0.012	1.006PheHis: 1.006 ± 0.007	1.583PheIle: 1.583 ± 0.009	1.673PheLys: 1.673 ± 0.008	3.775PheLeu: 3.775 ± 0.015	0.704PheMet: 0.704 ± 0.004	1.215PheAsn: 1.215 ± 0.007	1.973PhePro: 1.973 ± 0.009	1.756PheGln: 1.756 ± 0.008	1.899PheArg: 1.899 ± 0.01	3.312PheSer: 3.312 ± 0.013	1.874PheThr: 1.874 ± 0.01	1.949PheVal: 1.949 ± 0.009	0.44PheTrp: 0.44 ± 0.004	1.054PheTyr: 1.054 ± 0.007	0.004PheXaa: 0.004 ± 0.0
Gly	4.872GlyAla: 4.872 ± 0.022	1.261GlyCys: 1.261 ± 0.009	3.191GlyAsp: 3.191 ± 0.014	4.286GlyGlu: 4.286 ± 0.022	2.259GlyPhe: 2.259 ± 0.011	5.329GlyGly: 5.329 ± 0.024	1.77GlyHis: 1.77 ± 0.01	2.5GlyIle: 2.5 ± 0.011	3.69GlyLys: 3.69 ± 0.018	5.932GlyLeu: 5.932 ± 0.022	1.248GlyMet: 1.248 ± 0.007	2.22GlyAsn: 2.22 ± 0.01	4.741GlyPro: 4.741 ± 0.038	2.905GlyGln: 2.905 ± 0.011	4.088GlyArg: 4.088 ± 0.016	6.096GlySer: 6.096 ± 0.023	3.6GlyThr: 3.6 ± 0.013	3.49GlyVal: 3.49 ± 0.014	0.78GlyTrp: 0.78 ± 0.006	1.576GlyTyr: 1.576 ± 0.01	0.006GlyXaa: 0.006 ± 0.0
His	1.345HisAla: 1.345 ± 0.007	0.7HisCys: 0.7 ± 0.006	0.892HisAsp: 0.892 ± 0.005	1.344HisGlu: 1.344 ± 0.007	1.018HisPhe: 1.018 ± 0.006	1.572HisGly: 1.572 ± 0.009	0.915HisHis: 0.915 ± 0.007	1.173HisIle: 1.173 ± 0.007	1.252HisLys: 1.252 ± 0.008	2.971HisLeu: 2.971 ± 0.012	0.555HisMet: 0.555 ± 0.005	0.806HisAsn: 0.806 ± 0.006	1.725HisPro: 1.725 ± 0.01	1.421HisGln: 1.421 ± 0.01	1.661HisArg: 1.661 ± 0.008	2.345HisSer: 2.345 ± 0.011	1.508HisThr: 1.508 ± 0.011	1.531HisVal: 1.531 ± 0.008	0.343HisTrp: 0.343 ± 0.004	0.754HisTyr: 0.754 ± 0.006	0.003HisXaa: 0.003 ± 0.0
Ile	2.373IleAla: 2.373 ± 0.01	0.937IleCys: 0.937 ± 0.006	1.896IleAsp: 1.896 ± 0.012	2.493IleGlu: 2.493 ± 0.013	1.64IlePhe: 1.64 ± 0.01	1.987IleGly: 1.987 ± 0.01	1.287IleHis: 1.287 ± 0.01	2.056IleIle: 2.056 ± 0.012	2.477IleLys: 2.477 ± 0.012	4.142IleLeu: 4.142 ± 0.016	0.869IleMet: 0.869 ± 0.007	1.653IleAsn: 1.653 ± 0.009	2.501IlePro: 2.501 ± 0.011	2.223IleGln: 2.223 ± 0.012	2.257IleArg: 2.257 ± 0.01	3.47IleSer: 3.47 ± 0.014	2.338IleThr: 2.338 ± 0.012	2.205IleVal: 2.205 ± 0.011	0.457IleTrp: 0.457 ± 0.004	1.206IleTyr: 1.206 ± 0.007	0.003IleXaa: 0.003 ± 0.0
Lys	3.947LysAla: 3.947 ± 0.016	1.069LysCys: 1.069 ± 0.007	3.119LysAsp: 3.119 ± 0.014	5.236LysGlu: 5.236 ± 0.025	1.614LysPhe: 1.614 ± 0.008	3.167LysGly: 3.167 ± 0.02	1.382LysHis: 1.382 ± 0.009	2.588LysIle: 2.588 ± 0.011	4.598LysLys: 4.598 ± 0.022	5.147LysLeu: 5.147 ± 0.019	1.384LysMet: 1.384 ± 0.01	2.282LysAsn: 2.282 ± 0.012	3.144LysPro: 3.144 ± 0.017	2.714LysGln: 2.714 ± 0.015	3.341LysArg: 3.341 ± 0.013	3.947LysSer: 3.947 ± 0.017	3.052LysThr: 3.052 ± 0.012	3.38LysVal: 3.38 ± 0.013	0.573LysTrp: 0.573 ± 0.005	1.437LysTyr: 1.437 ± 0.008	0.005LysXaa: 0.005 ± 0.0
Leu	6.878LeuAla: 6.878 ± 0.022	2.151LeuCys: 2.151 ± 0.011	4.74LeuAsp: 4.74 ± 0.015	7.501LeuGlu: 7.501 ± 0.028	3.157LeuPhe: 3.157 ± 0.016	5.961LeuGly: 5.961 ± 0.02	2.767LeuHis: 2.767 ± 0.01	3.588LeuIle: 3.588 ± 0.016	5.796LeuLys: 5.796 ± 0.026	10.738LeuLeu: 10.738 ± 0.035	1.913LeuMet: 1.913 ± 0.008	3.363LeuAsn: 3.363 ± 0.012	6.351LeuPro: 6.351 ± 0.022	6.138LeuGln: 6.138 ± 0.024	6.132LeuArg: 6.132 ± 0.019	8.069LeuSer: 8.069 ± 0.021	4.95LeuThr: 4.95 ± 0.015	5.349LeuVal: 5.349 ± 0.018	1.112LeuTrp: 1.112 ± 0.007	2.362LeuTyr: 2.362 ± 0.011	0.008LeuXaa: 0.008 ± 0.001
Met	1.819MetAla: 1.819 ± 0.009	0.362MetCys: 0.362 ± 0.004	1.201MetAsp: 1.201 ± 0.007	1.832MetGlu: 1.832 ± 0.008	0.659MetPhe: 0.659 ± 0.005	1.219MetGly: 1.219 ± 0.008	0.453MetHis: 0.453 ± 0.004	0.742MetIle: 0.742 ± 0.005	1.37MetLys: 1.37 ± 0.007	1.868MetLeu: 1.868 ± 0.009	0.53MetMet: 0.53 ± 0.006	0.827MetAsn: 0.827 ± 0.006	1.073MetPro: 1.073 ± 0.011	0.958MetGln: 0.958 ± 0.007	1.013MetArg: 1.013 ± 0.006	1.481MetSer: 1.481 ± 0.007	1.047MetThr: 1.047 ± 0.006	1.294MetVal: 1.294 ± 0.007	0.221MetTrp: 0.221 ± 0.003	0.5MetTyr: 0.5 ± 0.004	0.001MetXaa: 0.001 ± 0.0
Asn	1.939AsnAla: 1.939 ± 0.009	0.756AsnCys: 0.756 ± 0.006	1.429AsnAsp: 1.429 ± 0.008	2.14AsnGlu: 2.14 ± 0.012	1.33AsnPhe: 1.33 ± 0.007	2.296AsnGly: 2.296 ± 0.012	0.896AsnHis: 0.896 ± 0.006	1.899AsnIle: 1.899 ± 0.009	2.088AsnLys: 2.088 ± 0.01	3.553AsnLeu: 3.553 ± 0.012	0.847AsnMet: 0.847 ± 0.006	1.389AsnAsn: 1.389 ± 0.009	2.085AsnPro: 2.085 ± 0.01	1.637AsnGln: 1.637 ± 0.008	1.757AsnArg: 1.757 ± 0.009	3.087AsnSer: 3.087 ± 0.013	1.887AsnThr: 1.887 ± 0.008	2.054AsnVal: 2.054 ± 0.009	0.42AsnTrp: 0.42 ± 0.004	0.988AsnTyr: 0.988 ± 0.007	0.003AsnXaa: 0.003 ± 0.0
Pro	5.664ProAla: 5.664 ± 0.031	1.143ProCys: 1.143 ± 0.01	2.874ProAsp: 2.874 ± 0.015	4.705ProGlu: 4.705 ± 0.022	1.906ProPhe: 1.906 ± 0.009	5.825ProGly: 5.825 ± 0.048	1.495ProHis: 1.495 ± 0.009	1.762ProIle: 1.762 ± 0.009	2.796ProLys: 2.796 ± 0.018	5.5ProLeu: 5.5 ± 0.019	1.013ProMet: 1.013 ± 0.006	1.755ProAsn: 1.755 ± 0.009	7.067ProPro: 7.067 ± 0.062	3.107ProGln: 3.107 ± 0.015	3.758ProArg: 3.758 ± 0.02	6.3ProSer: 6.3 ± 0.028	3.213ProThr: 3.213 ± 0.017	4.008ProVal: 4.008 ± 0.015	0.703ProTrp: 0.703 ± 0.006	1.467ProTyr: 1.467 ± 0.011	0.007ProXaa: 0.007 ± 0.001
Gln	3.787GlnAla: 3.787 ± 0.016	0.912GlnCys: 0.912 ± 0.008	2.422GlnAsp: 2.422 ± 0.01	4.138GlnGlu: 4.138 ± 0.022	1.33GlnPhe: 1.33 ± 0.006	2.992GlnGly: 2.992 ± 0.015	1.371GlnHis: 1.371 ± 0.008	1.929GlnIle: 1.929 ± 0.009	3.072GlnLys: 3.072 ± 0.015	5.061GlnLeu: 5.061 ± 0.023	1.133GlnMet: 1.133 ± 0.007	1.822GlnAsn: 1.822 ± 0.011	3.067GlnPro: 3.067 ± 0.017	3.429GlnGln: 3.429 ± 0.029	3.215GlnArg: 3.215 ± 0.016	3.337GlnSer: 3.337 ± 0.013	2.361GlnThr: 2.361 ± 0.011	2.887GlnVal: 2.887 ± 0.012	0.526GlnTrp: 0.526 ± 0.005	1.11GlnTyr: 1.11 ± 0.006	0.004GlnXaa: 0.004 ± 0.0
Arg	4.204ArgAla: 4.204 ± 0.017	1.242ArgCys: 1.242 ± 0.01	2.839ArgAsp: 2.839 ± 0.013	4.312ArgGlu: 4.312 ± 0.019	1.786ArgPhe: 1.786 ± 0.008	3.931ArgGly: 3.931 ± 0.022	1.583ArgHis: 1.583 ± 0.009	2.325ArgIle: 2.325 ± 0.011	3.717ArgLys: 3.717 ± 0.014	5.692ArgLeu: 5.692 ± 0.02	1.162ArgMet: 1.162 ± 0.007	2.027ArgAsn: 2.027 ± 0.009	3.637ArgPro: 3.637 ± 0.017	2.806ArgGln: 2.806 ± 0.012	4.759ArgArg: 4.759 ± 0.022	4.556ArgSer: 4.556 ± 0.023	2.878ArgThr: 2.878 ± 0.012	3.197ArgVal: 3.197 ± 0.011	0.709ArgTrp: 0.709 ± 0.006	1.348ArgTyr: 1.348 ± 0.007	0.004ArgXaa: 0.004 ± 0.0
Ser	5.721SerAla: 5.721 ± 0.021	1.801SerCys: 1.801 ± 0.012	3.969SerAsp: 3.969 ± 0.017	5.465SerGlu: 5.465 ± 0.021	2.923SerPhe: 2.923 ± 0.012	5.881SerGly: 5.881 ± 0.02	2.155SerHis: 2.155 ± 0.011	3.001SerIle: 3.001 ± 0.011	4.136SerLys: 4.136 ± 0.017	8.448SerLeu: 8.448 ± 0.022	1.546SerMet: 1.546 ± 0.007	2.594SerAsn: 2.594 ± 0.012	6.652SerPro: 6.652 ± 0.034	4.101SerGln: 4.101 ± 0.015	4.83SerArg: 4.83 ± 0.023	10.029SerSer: 10.029 ± 0.045	4.519SerThr: 4.519 ± 0.016	4.951SerVal: 4.951 ± 0.017	1.061SerTrp: 1.061 ± 0.007	1.955SerTyr: 1.955 ± 0.011	0.007SerXaa: 0.007 ± 0.001
Thr	3.841ThrAla: 3.841 ± 0.013	1.226ThrCys: 1.226 ± 0.009	2.382ThrAsp: 2.382 ± 0.01	3.555ThrGlu: 3.555 ± 0.014	1.96ThrPhe: 1.96 ± 0.009	3.518ThrGly: 3.518 ± 0.015	1.27ThrHis: 1.27 ± 0.008	2.117ThrIle: 2.117 ± 0.01	2.575ThrLys: 2.575 ± 0.011	5.159ThrLeu: 5.159 ± 0.016	1.012ThrMet: 1.012 ± 0.006	1.623ThrAsn: 1.623 ± 0.008	3.726ThrPro: 3.726 ± 0.016	2.343ThrGln: 2.343 ± 0.011	2.521ThrArg: 2.521 ± 0.011	4.766ThrSer: 4.766 ± 0.019	2.859ThrThr: 2.859 ± 0.016	3.715ThrVal: 3.715 ± 0.016	0.662ThrTrp: 0.662 ± 0.005	1.296ThrTyr: 1.296 ± 0.007	0.005ThrXaa: 0.005 ± 0.0
Val	4.279ValAla: 4.279 ± 0.016	1.398ValCys: 1.398 ± 0.008	2.894ValAsp: 2.894 ± 0.013	3.873ValGlu: 3.873 ± 0.014	2.21ValPhe: 2.21 ± 0.011	3.329ValGly: 3.329 ± 0.013	1.575ValHis: 1.575 ± 0.008	2.656ValIle: 2.656 ± 0.012	3.349ValLys: 3.349 ± 0.013	6.069ValLeu: 6.069 ± 0.018	1.232ValMet: 1.232 ± 0.007	2.143ValAsn: 2.143 ± 0.01	3.82ValPro: 3.82 ± 0.016	2.834ValGln: 2.834 ± 0.012	3.099ValArg: 3.099 ± 0.013	4.899ValSer: 4.899 ± 0.017	3.625ValThr: 3.625 ± 0.015	3.787ValVal: 3.787 ± 0.017	0.677ValTrp: 0.677 ± 0.005	1.506ValTyr: 1.506 ± 0.009	0.005ValXaa: 0.005 ± 0.001
Trp	0.805TrpAla: 0.805 ± 0.006	0.241TrpCys: 0.241 ± 0.003	0.622TrpAsp: 0.622 ± 0.005	0.813TrpGlu: 0.813 ± 0.006	0.4TrpPhe: 0.4 ± 0.004	0.746TrpGly: 0.746 ± 0.007	0.295TrpHis: 0.295 ± 0.004	0.478TrpIle: 0.478 ± 0.004	0.759TrpLys: 0.759 ± 0.005	1.167TrpLeu: 1.167 ± 0.007	0.298TrpMet: 0.298 ± 0.003	0.497TrpAsn: 0.497 ± 0.005	0.553TrpPro: 0.553 ± 0.005	0.532TrpGln: 0.532 ± 0.004	0.758TrpArg: 0.758 ± 0.006	0.847TrpSer: 0.847 ± 0.006	0.642TrpThr: 0.642 ± 0.006	0.647TrpVal: 0.647 ± 0.005	0.185TrpTrp: 0.185 ± 0.003	0.297TrpTyr: 0.297 ± 0.003	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.287TyrAla: 1.287 ± 0.007	0.635TyrCys: 0.635 ± 0.006	1.16TyrAsp: 1.16 ± 0.007	1.617TyrGlu: 1.617 ± 0.009	1.064TyrPhe: 1.064 ± 0.007	1.535TyrGly: 1.535 ± 0.009	0.711TyrHis: 0.711 ± 0.005	1.218TyrIle: 1.218 ± 0.008	1.354TyrLys: 1.354 ± 0.01	2.474TyrLeu: 2.474 ± 0.011	0.539TyrMet: 0.539 ± 0.004	0.971TyrAsn: 0.971 ± 0.006	1.226TyrPro: 1.226 ± 0.009	1.205TyrGln: 1.205 ± 0.006	1.545TyrArg: 1.545 ± 0.009	2.072TyrSer: 2.072 ± 0.009	1.32TyrThr: 1.32 ± 0.007	1.428TyrVal: 1.428 ± 0.009	0.322TyrTrp: 0.322 ± 0.005	0.858TyrTyr: 0.858 ± 0.006	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.006XaaAla: 0.006 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.004XaaAsp: 0.004 ± 0.0	0.006XaaGlu: 0.006 ± 0.0	0.004XaaPhe: 0.004 ± 0.0	0.008XaaGly: 0.008 ± 0.001	0.003XaaHis: 0.003 ± 0.0	0.003XaaIle: 0.003 ± 0.0	0.005XaaLys: 0.005 ± 0.0	0.008XaaLeu: 0.008 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.006XaaPro: 0.006 ± 0.0	0.004XaaGln: 0.004 ± 0.0	0.005XaaArg: 0.005 ± 0.0	0.005XaaSer: 0.005 ± 0.0	0.004XaaThr: 0.004 ± 0.0	0.005XaaVal: 0.005 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 45130 proteins (31182114 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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