Amino acid dipepetide frequency for Aurantimonas manganoxydans (strain ATCC BAA-1229 / DSM 21871 / SI85-9A1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.834AlaAla: 18.834 ± 0.183	1.1AlaCys: 1.1 ± 0.035	7.744AlaAsp: 7.744 ± 0.095	8.476AlaGlu: 8.476 ± 0.083	4.589AlaPhe: 4.589 ± 0.059	12.041AlaGly: 12.041 ± 0.117	2.157AlaHis: 2.157 ± 0.047	7.074AlaIle: 7.074 ± 0.085	3.583AlaLys: 3.583 ± 0.061	12.772AlaLeu: 12.772 ± 0.132	3.906AlaMet: 3.906 ± 0.067	2.719AlaAsn: 2.719 ± 0.05	5.941AlaPro: 5.941 ± 0.074	3.27AlaGln: 3.27 ± 0.055	9.294AlaArg: 9.294 ± 0.095	6.824AlaSer: 6.824 ± 0.088	6.585AlaThr: 6.585 ± 0.082	9.154AlaVal: 9.154 ± 0.102	1.325AlaTrp: 1.325 ± 0.037	2.56AlaTyr: 2.56 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.951CysAla: 0.951 ± 0.032	0.126CysCys: 0.126 ± 0.01	0.575CysAsp: 0.575 ± 0.023	0.487CysGlu: 0.487 ± 0.022	0.318CysPhe: 0.318 ± 0.019	0.961CysGly: 0.961 ± 0.031	0.265CysHis: 0.265 ± 0.014	0.375CysIle: 0.375 ± 0.016	0.15CysLys: 0.15 ± 0.013	0.819CysLeu: 0.819 ± 0.028	0.16CysMet: 0.16 ± 0.012	0.193CysAsn: 0.193 ± 0.013	0.453CysPro: 0.453 ± 0.023	0.213CysGln: 0.213 ± 0.014	0.833CysArg: 0.833 ± 0.03	0.451CysSer: 0.451 ± 0.02	0.397CysThr: 0.397 ± 0.02	0.591CysVal: 0.591 ± 0.022	0.117CysTrp: 0.117 ± 0.01	0.167CysTyr: 0.167 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.967AspAla: 7.967 ± 0.092	0.511AspCys: 0.511 ± 0.018	3.59AspAsp: 3.59 ± 0.076	3.746AspGlu: 3.746 ± 0.065	2.267AspPhe: 2.267 ± 0.045	6.006AspGly: 6.006 ± 0.093	1.317AspHis: 1.317 ± 0.039	3.1AspIle: 3.1 ± 0.051	1.52AspLys: 1.52 ± 0.032	6.131AspLeu: 6.131 ± 0.067	1.45AspMet: 1.45 ± 0.035	1.271AspAsn: 1.271 ± 0.039	3.685AspPro: 3.685 ± 0.063	1.573AspGln: 1.573 ± 0.042	5.165AspArg: 5.165 ± 0.069	2.109AspSer: 2.109 ± 0.045	2.781AspThr: 2.781 ± 0.062	4.273AspVal: 4.273 ± 0.059	0.922AspTrp: 0.922 ± 0.03	1.436AspTyr: 1.436 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	8.471GluAla: 8.471 ± 0.094	0.358GluCys: 0.358 ± 0.017	3.037GluAsp: 3.037 ± 0.059	3.29GluGlu: 3.29 ± 0.061	1.747GluPhe: 1.747 ± 0.038	4.542GluGly: 4.542 ± 0.078	1.146GluHis: 1.146 ± 0.033	3.634GluIle: 3.634 ± 0.056	2.002GluLys: 2.002 ± 0.05	5.026GluLeu: 5.026 ± 0.069	1.656GluMet: 1.656 ± 0.04	1.542GluAsn: 1.542 ± 0.035	2.964GluPro: 2.964 ± 0.065	1.789GluGln: 1.789 ± 0.042	5.492GluArg: 5.492 ± 0.078	2.392GluSer: 2.392 ± 0.042	4.137GluThr: 4.137 ± 0.066	3.538GluVal: 3.538 ± 0.06	0.676GluTrp: 0.676 ± 0.023	0.978GluTyr: 0.978 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.935PheAla: 4.935 ± 0.072	0.396PheCys: 0.396 ± 0.018	2.735PheAsp: 2.735 ± 0.051	2.171PheGlu: 2.171 ± 0.045	1.436PhePhe: 1.436 ± 0.041	3.775PheGly: 3.775 ± 0.064	0.715PheHis: 0.715 ± 0.024	1.564PheIle: 1.564 ± 0.043	0.809PheLys: 0.809 ± 0.025	3.353PheLeu: 3.353 ± 0.071	0.818PheMet: 0.818 ± 0.031	0.852PheAsn: 0.852 ± 0.023	1.582PhePro: 1.582 ± 0.041	0.985PheGln: 0.985 ± 0.028	2.387PheArg: 2.387 ± 0.05	2.08PheSer: 2.08 ± 0.046	1.876PheThr: 1.876 ± 0.039	3.075PheVal: 3.075 ± 0.046	0.494PheTrp: 0.494 ± 0.018	0.867PheTyr: 0.867 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.91GlyAla: 9.91 ± 0.108	0.914GlyCys: 0.914 ± 0.031	5.174GlyAsp: 5.174 ± 0.084	5.434GlyGlu: 5.434 ± 0.075	3.746GlyPhe: 3.746 ± 0.055	7.849GlyGly: 7.849 ± 0.109	2.027GlyHis: 2.027 ± 0.04	4.735GlyIle: 4.735 ± 0.071	2.733GlyLys: 2.733 ± 0.056	9.104GlyLeu: 9.104 ± 0.098	2.423GlyMet: 2.423 ± 0.045	2.084GlyAsn: 2.084 ± 0.06	3.773GlyPro: 3.773 ± 0.063	2.747GlyGln: 2.747 ± 0.051	7.122GlyArg: 7.122 ± 0.085	4.946GlySer: 4.946 ± 0.068	4.935GlyThr: 4.935 ± 0.069	6.269GlyVal: 6.269 ± 0.076	1.321GlyTrp: 1.321 ± 0.034	2.162GlyTyr: 2.162 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.288HisAla: 2.288 ± 0.047	0.257HisCys: 0.257 ± 0.015	1.222HisAsp: 1.222 ± 0.039	1.029HisGlu: 1.029 ± 0.033	0.785HisPhe: 0.785 ± 0.023	2.014HisGly: 2.014 ± 0.046	0.597HisHis: 0.597 ± 0.027	0.756HisIle: 0.756 ± 0.026	0.399HisLys: 0.399 ± 0.018	2.051HisLeu: 2.051 ± 0.046	0.471HisMet: 0.471 ± 0.019	0.395HisAsn: 0.395 ± 0.019	1.291HisPro: 1.291 ± 0.034	0.555HisGln: 0.555 ± 0.021	1.605HisArg: 1.605 ± 0.042	0.956HisSer: 0.956 ± 0.027	0.757HisThr: 0.757 ± 0.026	1.526HisVal: 1.526 ± 0.036	0.287HisTrp: 0.287 ± 0.017	0.473HisTyr: 0.473 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.787IleAla: 7.787 ± 0.074	0.527IleCys: 0.527 ± 0.023	3.753IleAsp: 3.753 ± 0.058	3.326IleGlu: 3.326 ± 0.055	1.809IlePhe: 1.809 ± 0.051	5.251IleGly: 5.251 ± 0.066	0.893IleHis: 0.893 ± 0.032	2.099IleIle: 2.099 ± 0.047	1.134IleLys: 1.134 ± 0.031	4.665IleLeu: 4.665 ± 0.067	0.966IleMet: 0.966 ± 0.03	1.161IleAsn: 1.161 ± 0.03	2.215IlePro: 2.215 ± 0.056	1.136IleGln: 1.136 ± 0.034	3.369IleArg: 3.369 ± 0.058	2.61IleSer: 2.61 ± 0.047	2.407IleThr: 2.407 ± 0.051	4.583IleVal: 4.583 ± 0.068	0.542IleTrp: 0.542 ± 0.022	1.019IleTyr: 1.019 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.807LysAla: 3.807 ± 0.061	0.13LysCys: 0.13 ± 0.01	1.529LysAsp: 1.529 ± 0.04	1.285LysGlu: 1.285 ± 0.035	0.716LysPhe: 0.716 ± 0.025	2.36LysGly: 2.36 ± 0.047	0.486LysHis: 0.486 ± 0.021	1.488LysIle: 1.488 ± 0.041	0.941LysLys: 0.941 ± 0.036	2.67LysLeu: 2.67 ± 0.059	0.666LysMet: 0.666 ± 0.028	0.718LysAsn: 0.718 ± 0.025	1.82LysPro: 1.82 ± 0.042	0.783LysGln: 0.783 ± 0.027	2.239LysArg: 2.239 ± 0.047	1.551LysSer: 1.551 ± 0.039	1.709LysThr: 1.709 ± 0.042	2.028LysVal: 2.028 ± 0.045	0.258LysTrp: 0.258 ± 0.017	0.487LysTyr: 0.487 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	13.754LeuAla: 13.754 ± 0.149	0.853LeuCys: 0.853 ± 0.024	6.211LeuAsp: 6.211 ± 0.094	4.914LeuGlu: 4.914 ± 0.066	3.629LeuPhe: 3.629 ± 0.067	8.093LeuGly: 8.093 ± 0.103	1.775LeuHis: 1.775 ± 0.046	4.661LeuIle: 4.661 ± 0.073	3.165LeuLys: 3.165 ± 0.061	8.618LeuLeu: 8.618 ± 0.126	2.227LeuMet: 2.227 ± 0.049	2.173LeuAsn: 2.173 ± 0.041	5.238LeuPro: 5.238 ± 0.062	2.541LeuGln: 2.541 ± 0.048	6.504LeuArg: 6.504 ± 0.082	6.132LeuSer: 6.132 ± 0.077	5.53LeuThr: 5.53 ± 0.076	7.733LeuVal: 7.733 ± 0.099	1.026LeuTrp: 1.026 ± 0.034	1.934LeuTyr: 1.934 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.269MetAla: 3.269 ± 0.052	0.145MetCys: 0.145 ± 0.011	1.226MetAsp: 1.226 ± 0.033	1.22MetGlu: 1.22 ± 0.033	0.693MetPhe: 0.693 ± 0.027	1.911MetGly: 1.911 ± 0.048	0.398MetHis: 0.398 ± 0.018	1.442MetIle: 1.442 ± 0.035	0.877MetLys: 0.877 ± 0.029	2.422MetLeu: 2.422 ± 0.046	0.701MetMet: 0.701 ± 0.028	0.708MetAsn: 0.708 ± 0.023	1.701MetPro: 1.701 ± 0.038	0.866MetGln: 0.866 ± 0.028	1.967MetArg: 1.967 ± 0.043	1.681MetSer: 1.681 ± 0.036	1.95MetThr: 1.95 ± 0.039	1.734MetVal: 1.734 ± 0.035	0.21MetTrp: 0.21 ± 0.014	0.279MetTyr: 0.279 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.948AsnAla: 2.948 ± 0.042	0.214AsnCys: 0.214 ± 0.014	1.36AsnAsp: 1.36 ± 0.04	1.206AsnGlu: 1.206 ± 0.033	0.877AsnPhe: 0.877 ± 0.027	2.31AsnGly: 2.31 ± 0.052	0.461AsnHis: 0.461 ± 0.018	1.149AsnIle: 1.149 ± 0.032	0.512AsnLys: 0.512 ± 0.023	2.219AsnLeu: 2.219 ± 0.046	0.557AsnMet: 0.557 ± 0.023	0.576AsnAsn: 0.576 ± 0.03	1.554AsnPro: 1.554 ± 0.037	0.67AsnGln: 0.67 ± 0.026	1.848AsnArg: 1.848 ± 0.038	1.103AsnSer: 1.103 ± 0.033	1.117AsnThr: 1.117 ± 0.032	1.757AsnVal: 1.757 ± 0.037	0.368AsnTrp: 0.368 ± 0.016	0.586AsnTyr: 0.586 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.895ProAla: 6.895 ± 0.103	0.367ProCys: 0.367 ± 0.019	3.927ProAsp: 3.927 ± 0.063	3.629ProGlu: 3.629 ± 0.06	1.984ProPhe: 1.984 ± 0.043	4.71ProGly: 4.71 ± 0.073	1.026ProHis: 1.026 ± 0.027	2.404ProIle: 2.404 ± 0.046	1.416ProLys: 1.416 ± 0.038	4.544ProLeu: 4.544 ± 0.071	1.282ProMet: 1.282 ± 0.035	1.234ProAsn: 1.234 ± 0.033	2.384ProPro: 2.384 ± 0.048	1.668ProGln: 1.668 ± 0.037	3.156ProArg: 3.156 ± 0.049	2.909ProSer: 2.909 ± 0.044	2.517ProThr: 2.517 ± 0.044	4.411ProVal: 4.411 ± 0.061	0.622ProTrp: 0.622 ± 0.021	1.113ProTyr: 1.113 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.698GlnAla: 3.698 ± 0.062	0.193GlnCys: 0.193 ± 0.013	1.447GlnAsp: 1.447 ± 0.04	1.451GlnGlu: 1.451 ± 0.041	0.951GlnPhe: 0.951 ± 0.029	2.124GlnGly: 2.124 ± 0.043	0.582GlnHis: 0.582 ± 0.022	1.757GlnIle: 1.757 ± 0.038	0.917GlnLys: 0.917 ± 0.029	2.428GlnLeu: 2.428 ± 0.046	0.911GlnMet: 0.911 ± 0.031	0.78GlnAsn: 0.78 ± 0.027	1.673GlnPro: 1.673 ± 0.04	0.992GlnGln: 0.992 ± 0.035	2.477GlnArg: 2.477 ± 0.05	1.699GlnSer: 1.699 ± 0.041	1.778GlnThr: 1.778 ± 0.037	1.92GlnVal: 1.92 ± 0.039	0.31GlnTrp: 0.31 ± 0.016	0.511GlnTyr: 0.511 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	7.979ArgAla: 7.979 ± 0.097	0.62ArgCys: 0.62 ± 0.025	4.484ArgAsp: 4.484 ± 0.069	4.426ArgGlu: 4.426 ± 0.061	3.13ArgPhe: 3.13 ± 0.055	5.303ArgGly: 5.303 ± 0.068	1.884ArgHis: 1.884 ± 0.047	4.227ArgIle: 4.227 ± 0.063	2.108ArgLys: 2.108 ± 0.054	8.246ArgLeu: 8.246 ± 0.1	2.042ArgMet: 2.042 ± 0.042	1.887ArgAsn: 1.887 ± 0.04	4.205ArgPro: 4.205 ± 0.071	2.811ArgGln: 2.811 ± 0.061	7.248ArgArg: 7.248 ± 0.116	4.405ArgSer: 4.405 ± 0.065	3.817ArgThr: 3.817 ± 0.059	4.76ArgVal: 4.76 ± 0.061	0.966ArgTrp: 0.966 ± 0.03	1.676ArgTyr: 1.676 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.26SerAla: 6.26 ± 0.077	0.481SerCys: 0.481 ± 0.023	3.23SerAsp: 3.23 ± 0.051	2.987SerGlu: 2.987 ± 0.047	2.275SerPhe: 2.275 ± 0.041	5.714SerGly: 5.714 ± 0.083	1.03SerHis: 1.03 ± 0.028	2.644SerIle: 2.644 ± 0.042	1.334SerLys: 1.334 ± 0.037	5.354SerLeu: 5.354 ± 0.071	1.311SerMet: 1.311 ± 0.029	1.293SerAsn: 1.293 ± 0.034	2.782SerPro: 2.782 ± 0.049	1.672SerGln: 1.672 ± 0.033	3.97SerArg: 3.97 ± 0.069	2.959SerSer: 2.959 ± 0.063	2.5SerThr: 2.5 ± 0.05	4.001SerVal: 4.001 ± 0.055	0.66SerTrp: 0.66 ± 0.024	1.247SerTyr: 1.247 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.775ThrAla: 6.775 ± 0.083	0.41ThrCys: 0.41 ± 0.019	3.02ThrAsp: 3.02 ± 0.051	2.801ThrGlu: 2.801 ± 0.052	1.825ThrPhe: 1.825 ± 0.041	5.546ThrGly: 5.546 ± 0.064	0.928ThrHis: 0.928 ± 0.031	3.222ThrIle: 3.222 ± 0.053	1.263ThrLys: 1.263 ± 0.034	5.659ThrLeu: 5.659 ± 0.067	1.31ThrMet: 1.31 ± 0.033	1.206ThrAsn: 1.206 ± 0.033	3.247ThrPro: 3.247 ± 0.047	1.3ThrGln: 1.3 ± 0.034	3.629ThrArg: 3.629 ± 0.065	2.746ThrSer: 2.746 ± 0.048	2.881ThrThr: 2.881 ± 0.055	4.527ThrVal: 4.527 ± 0.07	0.513ThrTrp: 0.513 ± 0.019	1.117ThrTyr: 1.117 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	9.945ValAla: 9.945 ± 0.098	0.669ValCys: 0.669 ± 0.025	4.472ValAsp: 4.472 ± 0.066	4.774ValGlu: 4.774 ± 0.066	2.813ValPhe: 2.813 ± 0.05	6.002ValGly: 6.002 ± 0.079	1.32ValHis: 1.32 ± 0.035	3.565ValIle: 3.565 ± 0.066	1.916ValLys: 1.916 ± 0.04	7.029ValLeu: 7.029 ± 0.092	1.818ValMet: 1.818 ± 0.042	1.73ValAsn: 1.73 ± 0.04	3.924ValPro: 3.924 ± 0.058	1.853ValGln: 1.853 ± 0.041	5.055ValArg: 5.055 ± 0.063	4.336ValSer: 4.336 ± 0.064	4.559ValThr: 4.559 ± 0.061	6.057ValVal: 6.057 ± 0.078	0.926ValTrp: 0.926 ± 0.03	1.439ValTyr: 1.439 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.078TrpAla: 1.078 ± 0.028	0.133TrpCys: 0.133 ± 0.01	0.602TrpAsp: 0.602 ± 0.024	0.531TrpGlu: 0.531 ± 0.02	0.526TrpPhe: 0.526 ± 0.021	0.788TrpGly: 0.788 ± 0.025	0.284TrpHis: 0.284 ± 0.014	0.596TrpIle: 0.596 ± 0.024	0.366TrpLys: 0.366 ± 0.018	1.423TrpLeu: 1.423 ± 0.034	0.34TrpMet: 0.34 ± 0.018	0.381TrpAsn: 0.381 ± 0.018	0.685TrpPro: 0.685 ± 0.025	0.538TrpGln: 0.538 ± 0.022	1.105TrpArg: 1.105 ± 0.032	0.771TrpSer: 0.771 ± 0.026	0.727TrpThr: 0.727 ± 0.025	0.727TrpVal: 0.727 ± 0.027	0.213TrpTrp: 0.213 ± 0.014	0.255TrpTyr: 0.255 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.397TyrAla: 2.397 ± 0.05	0.2TyrCys: 0.2 ± 0.013	1.479TyrAsp: 1.479 ± 0.038	1.236TyrGlu: 1.236 ± 0.037	0.787TyrPhe: 0.787 ± 0.028	2.106TyrGly: 2.106 ± 0.042	0.423TyrHis: 0.423 ± 0.021	0.757TyrIle: 0.757 ± 0.024	0.528TyrLys: 0.528 ± 0.018	2.18TyrLeu: 2.18 ± 0.045	0.384TyrMet: 0.384 ± 0.018	0.488TyrAsn: 0.488 ± 0.023	1.078TyrPro: 1.078 ± 0.031	0.634TyrGln: 0.634 ± 0.022	1.759TyrArg: 1.759 ± 0.045	1.043TyrSer: 1.043 ± 0.032	0.97TyrThr: 0.97 ± 0.027	1.539TyrVal: 1.539 ± 0.039	0.314TyrTrp: 0.314 ± 0.017	0.54TyrTyr: 0.54 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3625 proteins (1230513 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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