Amino acid dipepetide frequency for Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Sporotrichum thermophile)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.318AlaAla: 13.318 ± 0.097
1.066AlaCys: 1.066 ± 0.019
5.034AlaAsp: 5.034 ± 0.04
6.248AlaGlu: 6.248 ± 0.063
3.037AlaPhe: 3.037 ± 0.033
7.388AlaGly: 7.388 ± 0.048
1.915AlaHis: 1.915 ± 0.022
3.816AlaIle: 3.816 ± 0.037
4.167AlaLys: 4.167 ± 0.041
8.314AlaLeu: 8.314 ± 0.047
1.917AlaMet: 1.917 ± 0.025
2.933AlaAsn: 2.933 ± 0.028
6.038AlaPro: 6.038 ± 0.069
3.679AlaGln: 3.679 ± 0.039
6.462AlaArg: 6.462 ± 0.043
7.749AlaSer: 7.749 ± 0.052
5.692AlaThr: 5.692 ± 0.045
6.241AlaVal: 6.241 ± 0.041
1.231AlaTrp: 1.231 ± 0.018
2.137AlaTyr: 2.137 ± 0.026
0.0AlaXaa: 0.0 ± 0.0
Cys
0.95CysAla: 0.95 ± 0.016
0.239CysCys: 0.239 ± 0.009
0.584CysAsp: 0.584 ± 0.013
0.55CysGlu: 0.55 ± 0.012
0.486CysPhe: 0.486 ± 0.011
0.945CysGly: 0.945 ± 0.019
0.293CysHis: 0.293 ± 0.009
0.556CysIle: 0.556 ± 0.012
0.435CysLys: 0.435 ± 0.011
1.155CysLeu: 1.155 ± 0.019
0.23CysMet: 0.23 ± 0.007
0.373CysAsn: 0.373 ± 0.01
0.677CysPro: 0.677 ± 0.014
0.388CysGln: 0.388 ± 0.011
0.812CysArg: 0.812 ± 0.014
0.818CysSer: 0.818 ± 0.018
0.599CysThr: 0.599 ± 0.011
0.746CysVal: 0.746 ± 0.015
0.193CysTrp: 0.193 ± 0.008
0.321CysTyr: 0.321 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.234AspAla: 5.234 ± 0.039
0.596AspCys: 0.596 ± 0.012
4.789AspAsp: 4.789 ± 0.063
4.68AspGlu: 4.68 ± 0.04
2.027AspPhe: 2.027 ± 0.024
4.751AspGly: 4.751 ± 0.041
1.168AspHis: 1.168 ± 0.019
2.462AspIle: 2.462 ± 0.025
2.353AspLys: 2.353 ± 0.031
4.834AspLeu: 4.834 ± 0.039
1.201AspMet: 1.201 ± 0.016
1.709AspAsn: 1.709 ± 0.024
3.589AspPro: 3.589 ± 0.026
1.724AspGln: 1.724 ± 0.022
3.486AspArg: 3.486 ± 0.045
3.755AspSer: 3.755 ± 0.034
2.603AspThr: 2.603 ± 0.027
3.635AspVal: 3.635 ± 0.032
0.847AspTrp: 0.847 ± 0.014
1.465AspTyr: 1.465 ± 0.021
0.0AspXaa: 0.0 ± 0.0
Glu
6.172GluAla: 6.172 ± 0.058
0.59GluCys: 0.59 ± 0.015
4.206GluAsp: 4.206 ± 0.042
6.431GluGlu: 6.431 ± 0.08
1.827GluPhe: 1.827 ± 0.024
4.311GluGly: 4.311 ± 0.041
1.383GluHis: 1.383 ± 0.017
2.585GluIle: 2.585 ± 0.028
3.54GluLys: 3.54 ± 0.04
5.307GluLeu: 5.307 ± 0.044
1.412GluMet: 1.412 ± 0.02
1.955GluAsn: 1.955 ± 0.021
3.219GluPro: 3.219 ± 0.062
2.602GluGln: 2.602 ± 0.031
4.565GluArg: 4.565 ± 0.043
3.949GluSer: 3.949 ± 0.041
3.42GluThr: 3.42 ± 0.032
3.682GluVal: 3.682 ± 0.033
0.88GluTrp: 0.88 ± 0.016
1.585GluTyr: 1.585 ± 0.019
0.0GluXaa: 0.0 ± 0.0
Phe
3.049PheAla: 3.049 ± 0.031
0.49PheCys: 0.49 ± 0.012
2.11PheAsp: 2.11 ± 0.024
1.976PheGlu: 1.976 ± 0.019
1.446PhePhe: 1.446 ± 0.023
2.746PheGly: 2.746 ± 0.033
0.784PheHis: 0.784 ± 0.014
1.433PheIle: 1.433 ± 0.021
1.268PheLys: 1.268 ± 0.018
3.234PheLeu: 3.234 ± 0.036
0.642PheMet: 0.642 ± 0.013
1.165PheAsn: 1.165 ± 0.018
1.918PhePro: 1.918 ± 0.027
1.173PheGln: 1.173 ± 0.018
2.088PheArg: 2.088 ± 0.023
2.637PheSer: 2.637 ± 0.029
1.873PheThr: 1.873 ± 0.024
2.321PheVal: 2.321 ± 0.025
0.567PheTrp: 0.567 ± 0.012
0.992PheTyr: 0.992 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
6.612GlyAla: 6.612 ± 0.055
0.86GlyCys: 0.86 ± 0.015
4.11GlyAsp: 4.11 ± 0.038
4.335GlyGlu: 4.335 ± 0.035
2.655GlyPhe: 2.655 ± 0.032
8.192GlyGly: 8.192 ± 0.082
1.71GlyHis: 1.71 ± 0.02
3.132GlyIle: 3.132 ± 0.029
3.464GlyLys: 3.464 ± 0.037
6.122GlyLeu: 6.122 ± 0.043
1.545GlyMet: 1.545 ± 0.019
2.497GlyAsn: 2.497 ± 0.025
4.053GlyPro: 4.053 ± 0.038
2.648GlyGln: 2.648 ± 0.028
5.113GlyArg: 5.113 ± 0.04
6.334GlySer: 6.334 ± 0.051
4.23GlyThr: 4.23 ± 0.038
4.61GlyVal: 4.61 ± 0.037
1.182GlyTrp: 1.182 ± 0.018
2.052GlyTyr: 2.052 ± 0.027
0.0GlyXaa: 0.0 ± 0.0
His
1.96HisAla: 1.96 ± 0.023
0.291HisCys: 0.291 ± 0.008
1.263HisAsp: 1.263 ± 0.017
1.204HisGlu: 1.204 ± 0.019
0.823HisPhe: 0.823 ± 0.014
1.814HisGly: 1.814 ± 0.024
1.042HisHis: 1.042 ± 0.024
0.996HisIle: 0.996 ± 0.015
0.815HisLys: 0.815 ± 0.013
2.106HisLeu: 2.106 ± 0.023
0.436HisMet: 0.436 ± 0.01
0.739HisAsn: 0.739 ± 0.013
1.78HisPro: 1.78 ± 0.023
1.039HisGln: 1.039 ± 0.019
1.62HisArg: 1.62 ± 0.024
1.621HisSer: 1.621 ± 0.023
1.118HisThr: 1.118 ± 0.017
1.39HisVal: 1.39 ± 0.018
0.32HisTrp: 0.32 ± 0.008
0.669HisTyr: 0.669 ± 0.011
0.0HisXaa: 0.0 ± 0.0
Ile
3.706IleAla: 3.706 ± 0.034
0.592IleCys: 0.592 ± 0.012
2.377IleAsp: 2.377 ± 0.024
2.489IleGlu: 2.489 ± 0.028
1.554IlePhe: 1.554 ± 0.024
2.695IleGly: 2.695 ± 0.031
0.98IleHis: 0.98 ± 0.016
1.951IleIle: 1.951 ± 0.028
1.876IleLys: 1.876 ± 0.024
3.831IleLeu: 3.831 ± 0.041
0.837IleMet: 0.837 ± 0.015
1.444IleAsn: 1.444 ± 0.021
2.643IlePro: 2.643 ± 0.024
1.485IleGln: 1.485 ± 0.02
2.721IleArg: 2.721 ± 0.025
2.991IleSer: 2.991 ± 0.03
2.377IleThr: 2.377 ± 0.029
2.759IleVal: 2.759 ± 0.028
0.599IleTrp: 0.599 ± 0.012
1.161IleTyr: 1.161 ± 0.019
0.0IleXaa: 0.0 ± 0.0
Lys
4.25LysAla: 4.25 ± 0.04
0.412LysCys: 0.412 ± 0.01
2.441LysAsp: 2.441 ± 0.026
3.302LysGlu: 3.302 ± 0.036
1.249LysPhe: 1.249 ± 0.019
2.996LysGly: 2.996 ± 0.033
1.013LysHis: 1.013 ± 0.015
1.875LysIle: 1.875 ± 0.025
3.29LysLys: 3.29 ± 0.063
3.702LysLeu: 3.702 ± 0.037
0.905LysMet: 0.905 ± 0.016
1.45LysAsn: 1.45 ± 0.022
2.765LysPro: 2.765 ± 0.029
1.718LysGln: 1.718 ± 0.021
3.459LysArg: 3.459 ± 0.034
2.912LysSer: 2.912 ± 0.031
2.616LysThr: 2.616 ± 0.026
2.588LysVal: 2.588 ± 0.027
0.602LysTrp: 0.602 ± 0.013
1.208LysTyr: 1.208 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
8.732LeuAla: 8.732 ± 0.055
1.09LeuCys: 1.09 ± 0.018
5.085LeuAsp: 5.085 ± 0.036
5.422LeuGlu: 5.422 ± 0.05
3.081LeuPhe: 3.081 ± 0.033
6.092LeuGly: 6.092 ± 0.044
2.003LeuHis: 2.003 ± 0.02
3.3LeuIle: 3.3 ± 0.032
3.718LeuLys: 3.718 ± 0.037
8.267LeuLeu: 8.267 ± 0.066
1.615LeuMet: 1.615 ± 0.02
2.701LeuAsn: 2.701 ± 0.029
5.718LeuPro: 5.718 ± 0.041
3.393LeuGln: 3.393 ± 0.032
6.518LeuArg: 6.518 ± 0.052
6.742LeuSer: 6.742 ± 0.047
4.49LeuThr: 4.49 ± 0.032
5.629LeuVal: 5.629 ± 0.043
1.165LeuTrp: 1.165 ± 0.019
2.132LeuTyr: 2.132 ± 0.028
0.0LeuXaa: 0.0 ± 0.0
Met
2.284MetAla: 2.284 ± 0.024
0.213MetCys: 0.213 ± 0.007
1.122MetAsp: 1.122 ± 0.016
1.151MetGlu: 1.151 ± 0.018
0.651MetPhe: 0.651 ± 0.013
1.376MetGly: 1.376 ± 0.018
0.417MetHis: 0.417 ± 0.01
0.781MetIle: 0.781 ± 0.016
0.789MetLys: 0.789 ± 0.014
1.754MetLeu: 1.754 ± 0.021
0.526MetMet: 0.526 ± 0.013
0.615MetAsn: 0.615 ± 0.012
1.24MetPro: 1.24 ± 0.016
0.738MetGln: 0.738 ± 0.014
1.314MetArg: 1.314 ± 0.016
1.582MetSer: 1.582 ± 0.02
1.191MetThr: 1.191 ± 0.018
1.247MetVal: 1.247 ± 0.018
0.237MetTrp: 0.237 ± 0.007
0.47MetTyr: 0.47 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
2.828AsnAla: 2.828 ± 0.025
0.358AsnCys: 0.358 ± 0.009
1.696AsnAsp: 1.696 ± 0.022
1.695AsnGlu: 1.695 ± 0.019
1.127AsnPhe: 1.127 ± 0.017
2.847AsnGly: 2.847 ± 0.029
0.765AsnHis: 0.765 ± 0.014
1.551AsnIle: 1.551 ± 0.019
1.417AsnLys: 1.417 ± 0.019
2.874AsnLeu: 2.874 ± 0.029
0.675AsnMet: 0.675 ± 0.014
1.635AsnAsn: 1.635 ± 0.041
2.408AsnPro: 2.408 ± 0.028
1.135AsnGln: 1.135 ± 0.017
1.953AsnArg: 1.953 ± 0.023
2.26AsnSer: 2.26 ± 0.028
1.83AsnThr: 1.83 ± 0.023
1.958AsnVal: 1.958 ± 0.022
0.47AsnTrp: 0.47 ± 0.01
0.885AsnTyr: 0.885 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
7.092ProAla: 7.092 ± 0.074
0.546ProCys: 0.546 ± 0.014
3.596ProAsp: 3.596 ± 0.029
4.104ProGlu: 4.104 ± 0.05
1.997ProPhe: 1.997 ± 0.024
4.903ProGly: 4.903 ± 0.041
1.387ProHis: 1.387 ± 0.02
2.216ProIle: 2.216 ± 0.026
2.552ProLys: 2.552 ± 0.025
4.965ProLeu: 4.965 ± 0.039
1.002ProMet: 1.002 ± 0.018
2.056ProAsn: 2.056 ± 0.021
7.055ProPro: 7.055 ± 0.104
2.583ProGln: 2.583 ± 0.037
4.164ProArg: 4.164 ± 0.035
6.394ProSer: 6.394 ± 0.058
4.149ProThr: 4.149 ± 0.04
3.941ProVal: 3.941 ± 0.037
0.753ProTrp: 0.753 ± 0.015
1.495ProTyr: 1.495 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
3.651GlnAla: 3.651 ± 0.036
0.379GlnCys: 0.379 ± 0.01
1.872GlnAsp: 1.872 ± 0.019
2.371GlnGlu: 2.371 ± 0.03
1.158GlnPhe: 1.158 ± 0.016
2.44GlnGly: 2.44 ± 0.028
1.139GlnHis: 1.139 ± 0.023
1.522GlnIle: 1.522 ± 0.022
1.738GlnLys: 1.738 ± 0.022
3.279GlnLeu: 3.279 ± 0.031
0.778GlnMet: 0.778 ± 0.015
1.234GlnAsn: 1.234 ± 0.02
2.898GlnPro: 2.898 ± 0.043
3.598GlnGln: 3.598 ± 0.089
2.789GlnArg: 2.789 ± 0.026
2.699GlnSer: 2.699 ± 0.031
2.128GlnThr: 2.128 ± 0.023
2.049GlnVal: 2.049 ± 0.021
0.514GlnTrp: 0.514 ± 0.013
1.01GlnTyr: 1.01 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
6.178ArgAla: 6.178 ± 0.043
0.767ArgCys: 0.767 ± 0.015
3.876ArgAsp: 3.876 ± 0.044
4.65ArgGlu: 4.65 ± 0.043
2.275ArgPhe: 2.275 ± 0.028
4.59ArgGly: 4.59 ± 0.041
1.763ArgHis: 1.763 ± 0.023
2.853ArgIle: 2.853 ± 0.026
3.47ArgLys: 3.47 ± 0.035
6.115ArgLeu: 6.115 ± 0.048
1.397ArgMet: 1.397 ± 0.016
2.185ArgAsn: 2.185 ± 0.027
4.369ArgPro: 4.369 ± 0.043
2.85ArgGln: 2.85 ± 0.029
6.563ArgArg: 6.563 ± 0.06
5.116ArgSer: 5.116 ± 0.051
3.488ArgThr: 3.488 ± 0.033
3.828ArgVal: 3.828 ± 0.034
1.025ArgTrp: 1.025 ± 0.015
1.721ArgTyr: 1.721 ± 0.024
0.0ArgXaa: 0.0 ± 0.0
Ser
7.337SerAla: 7.337 ± 0.054
0.802SerCys: 0.802 ± 0.015
3.938SerAsp: 3.938 ± 0.035
3.878SerGlu: 3.878 ± 0.041
2.635SerPhe: 2.635 ± 0.03
5.951SerGly: 5.951 ± 0.039
1.748SerHis: 1.748 ± 0.023
3.109SerIle: 3.109 ± 0.03
3.147SerLys: 3.147 ± 0.034
6.615SerLeu: 6.615 ± 0.049
1.44SerMet: 1.44 ± 0.021
2.469SerAsn: 2.469 ± 0.027
5.978SerPro: 5.978 ± 0.059
2.967SerGln: 2.967 ± 0.033
5.361SerArg: 5.361 ± 0.055
9.249SerSer: 9.249 ± 0.096
5.036SerThr: 5.036 ± 0.039
4.303SerVal: 4.303 ± 0.037
1.007SerTrp: 1.007 ± 0.015
1.794SerTyr: 1.794 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
5.856ThrAla: 5.856 ± 0.043
0.678ThrCys: 0.678 ± 0.015
2.665ThrAsp: 2.665 ± 0.027
2.936ThrGlu: 2.936 ± 0.03
1.96ThrPhe: 1.96 ± 0.025
4.329ThrGly: 4.329 ± 0.041
1.153ThrHis: 1.153 ± 0.017
2.574ThrIle: 2.574 ± 0.027
2.338ThrLys: 2.338 ± 0.027
4.785ThrLeu: 4.785 ± 0.039
1.024ThrMet: 1.024 ± 0.018
1.796ThrAsn: 1.796 ± 0.023
4.556ThrPro: 4.556 ± 0.046
1.859ThrGln: 1.859 ± 0.02
3.334ThrArg: 3.334 ± 0.026
4.825ThrSer: 4.825 ± 0.047
4.766ThrThr: 4.766 ± 0.062
3.717ThrVal: 3.717 ± 0.036
0.761ThrTrp: 0.761 ± 0.014
1.401ThrTyr: 1.401 ± 0.019
0.0ThrXaa: 0.0 ± 0.0
Val
5.85ValAla: 5.85 ± 0.044
0.828ValCys: 0.828 ± 0.017
3.704ValAsp: 3.704 ± 0.031
3.897ValGlu: 3.897 ± 0.035
2.362ValPhe: 2.362 ± 0.024
4.184ValGly: 4.184 ± 0.037
1.339ValHis: 1.339 ± 0.018
2.586ValIle: 2.586 ± 0.03
2.694ValLys: 2.694 ± 0.028
5.807ValLeu: 5.807 ± 0.05
1.24ValMet: 1.24 ± 0.018
1.928ValAsn: 1.928 ± 0.023
3.993ValPro: 3.993 ± 0.036
2.168ValGln: 2.168 ± 0.025
4.042ValArg: 4.042 ± 0.037
4.462ValSer: 4.462 ± 0.036
3.457ValThr: 3.457 ± 0.035
4.67ValVal: 4.67 ± 0.044
0.887ValTrp: 0.887 ± 0.018
1.678ValTyr: 1.678 ± 0.023
0.0ValXaa: 0.0 ± 0.0
Trp
1.223TrpAla: 1.223 ± 0.019
0.184TrpCys: 0.184 ± 0.006
0.899TrpAsp: 0.899 ± 0.016
0.877TrpGlu: 0.877 ± 0.015
0.505TrpPhe: 0.505 ± 0.011
0.91TrpGly: 0.91 ± 0.015
0.34TrpHis: 0.34 ± 0.01
0.607TrpIle: 0.607 ± 0.011
0.714TrpLys: 0.714 ± 0.013
1.314TrpLeu: 1.314 ± 0.021
0.326TrpMet: 0.326 ± 0.009
0.54TrpAsn: 0.54 ± 0.011
0.608TrpPro: 0.608 ± 0.013
0.518TrpGln: 0.518 ± 0.011
1.029TrpArg: 1.029 ± 0.017
0.94TrpSer: 0.94 ± 0.015
0.847TrpThr: 0.847 ± 0.017
0.865TrpVal: 0.865 ± 0.015
0.282TrpTrp: 0.282 ± 0.009
0.398TrpTyr: 0.398 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.1TyrAla: 2.1 ± 0.024
0.371TyrCys: 0.371 ± 0.009
1.542TyrAsp: 1.542 ± 0.019
1.423TyrGlu: 1.423 ± 0.02
1.053TyrPhe: 1.053 ± 0.02
1.995TyrGly: 1.995 ± 0.026
0.703TyrHis: 0.703 ± 0.014
1.165TyrIle: 1.165 ± 0.017
0.967TyrLys: 0.967 ± 0.017
2.513TyrLeu: 2.513 ± 0.028
0.549TyrMet: 0.549 ± 0.012
0.947TyrAsn: 0.947 ± 0.015
1.448TyrPro: 1.448 ± 0.023
0.981TyrGln: 0.981 ± 0.016
1.687TyrArg: 1.687 ± 0.021
1.729TyrSer: 1.729 ± 0.02
1.402TyrThr: 1.402 ± 0.021
1.596TyrVal: 1.596 ± 0.022
0.402TyrTrp: 0.402 ± 0.01
0.913TyrTyr: 0.913 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9079 proteins (4302111 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski