Amino acid dipepetide frequency for Beihai picorna-like virus 117

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.217AlaAla: 6.217 ± 3.87
0.311AlaCys: 0.311 ± 0.412
3.73AlaAsp: 3.73 ± 1.033
3.108AlaGlu: 3.108 ± 0.77
1.865AlaPhe: 1.865 ± 0.53
4.663AlaGly: 4.663 ± 2.039
0.311AlaHis: 0.311 ± 0.157
2.798AlaIle: 2.798 ± 1.417
4.352AlaLys: 4.352 ± 2.833
4.352AlaLeu: 4.352 ± 0.585
1.243AlaMet: 1.243 ± 0.282
4.974AlaAsn: 4.974 ± 1.751
3.419AlaPro: 3.419 ± 1.898
3.419AlaGln: 3.419 ± 3.986
1.243AlaArg: 1.243 ± 0.601
5.284AlaSer: 5.284 ± 1.712
5.595AlaThr: 5.595 ± 1.47
4.352AlaVal: 4.352 ± 1.732
0.933AlaTrp: 0.933 ± 0.245
2.176AlaTyr: 2.176 ± 2.561
0.0AlaXaa: 0.0 ± 0.0
Cys
0.933CysAla: 0.933 ± 0.472
0.0CysCys: 0.0 ± 0.0
0.311CysAsp: 0.311 ± 0.157
0.933CysGlu: 0.933 ± 0.472
0.311CysPhe: 0.311 ± 0.412
1.243CysGly: 1.243 ± 0.282
0.311CysHis: 0.311 ± 0.157
0.622CysIle: 0.622 ± 0.3
0.622CysLys: 0.622 ± 0.315
0.933CysLeu: 0.933 ± 0.704
0.0CysMet: 0.0 ± 0.0
0.311CysAsn: 0.311 ± 0.157
1.554CysPro: 1.554 ± 1.001
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.865CysSer: 1.865 ± 0.49
2.798CysThr: 2.798 ± 0.959
0.622CysVal: 0.622 ± 0.315
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.73AspAla: 3.73 ± 1.421
0.933AspCys: 0.933 ± 0.472
5.284AspAsp: 5.284 ± 1.036
6.217AspGlu: 6.217 ± 2.671
2.176AspPhe: 2.176 ± 1.102
2.798AspGly: 2.798 ± 0.341
0.622AspHis: 0.622 ± 0.315
4.352AspIle: 4.352 ± 1.038
3.108AspLys: 3.108 ± 0.249
2.487AspLeu: 2.487 ± 0.563
0.622AspMet: 0.622 ± 0.811
2.798AspAsn: 2.798 ± 0.341
2.487AspPro: 2.487 ± 1.202
0.622AspGln: 0.622 ± 0.315
2.487AspArg: 2.487 ± 0.762
3.108AspSer: 3.108 ± 2.002
1.865AspThr: 1.865 ± 0.945
3.73AspVal: 3.73 ± 1.89
0.311AspTrp: 0.311 ± 0.412
2.487AspTyr: 2.487 ± 0.762
0.0AspXaa: 0.0 ± 0.0
Glu
3.108GluAla: 3.108 ± 1.231
1.554GluCys: 1.554 ± 1.001
2.487GluAsp: 2.487 ± 0.762
1.865GluGlu: 1.865 ± 0.517
3.419GluPhe: 3.419 ± 0.779
2.798GluGly: 2.798 ± 0.533
1.554GluHis: 1.554 ± 0.787
2.798GluIle: 2.798 ± 1.117
3.73GluLys: 3.73 ± 1.197
3.419GluLeu: 3.419 ± 0.241
1.865GluMet: 1.865 ± 0.945
2.798GluAsn: 2.798 ± 1.278
2.487GluPro: 2.487 ± 0.563
2.798GluGln: 2.798 ± 0.533
4.663GluArg: 4.663 ± 2.498
3.108GluSer: 3.108 ± 1.502
4.352GluThr: 4.352 ± 1.008
4.041GluVal: 4.041 ± 0.933
0.311GluTrp: 0.311 ± 0.157
1.865GluTyr: 1.865 ± 0.517
0.0GluXaa: 0.0 ± 0.0
Phe
1.243PheAla: 1.243 ± 0.63
0.311PheCys: 0.311 ± 0.412
4.352PheAsp: 4.352 ± 0.585
3.73PheGlu: 3.73 ± 1.344
1.243PhePhe: 1.243 ± 0.63
1.243PheGly: 1.243 ± 0.726
2.487PheHis: 2.487 ± 1.202
2.798PheIle: 2.798 ± 0.656
2.487PheLys: 2.487 ± 1.451
3.419PheLeu: 3.419 ± 0.779
0.622PheMet: 0.622 ± 0.315
3.108PheAsn: 3.108 ± 1.102
1.554PhePro: 1.554 ± 0.385
1.865PheGln: 1.865 ± 0.765
3.108PheArg: 3.108 ± 0.582
2.487PheSer: 2.487 ± 0.808
2.487PheThr: 2.487 ± 1.26
0.622PheVal: 0.622 ± 0.315
0.311PheTrp: 0.311 ± 0.157
1.243PheTyr: 1.243 ± 0.601
0.0PheXaa: 0.0 ± 0.0
Gly
0.933GlyAla: 0.933 ± 0.851
0.622GlyCys: 0.622 ± 0.315
2.487GlyAsp: 2.487 ± 1.26
2.487GlyGlu: 2.487 ± 0.762
1.865GlyPhe: 1.865 ± 0.759
3.73GlyGly: 3.73 ± 3.403
1.554GlyHis: 1.554 ± 0.385
4.352GlyIle: 4.352 ± 1.132
3.73GlyLys: 3.73 ± 1.421
4.974GlyLeu: 4.974 ± 2.734
1.554GlyMet: 1.554 ± 0.525
3.73GlyAsn: 3.73 ± 2.439
1.865GlyPro: 1.865 ± 0.49
4.041GlyGln: 4.041 ± 0.11
4.352GlyArg: 4.352 ± 2.599
3.73GlySer: 3.73 ± 1.89
3.73GlyThr: 3.73 ± 2.177
4.663GlyVal: 4.663 ± 0.206
0.311GlyTrp: 0.311 ± 0.412
2.487GlyTyr: 2.487 ± 0.563
0.0GlyXaa: 0.0 ± 0.0
His
2.176HisAla: 2.176 ± 0.82
0.622HisCys: 0.622 ± 0.315
0.933HisAsp: 0.933 ± 0.472
0.622HisGlu: 0.622 ± 0.3
0.622HisPhe: 0.622 ± 0.315
1.554HisGly: 1.554 ± 0.787
1.554HisHis: 1.554 ± 0.385
1.865HisIle: 1.865 ± 0.945
2.487HisLys: 2.487 ± 0.563
2.176HisLeu: 2.176 ± 1.102
0.311HisMet: 0.311 ± 0.287
2.487HisAsn: 2.487 ± 0.808
1.865HisPro: 1.865 ± 0.517
1.554HisGln: 1.554 ± 0.385
1.243HisArg: 1.243 ± 0.282
1.243HisSer: 1.243 ± 0.282
1.554HisThr: 1.554 ± 0.385
1.243HisVal: 1.243 ± 0.282
0.0HisTrp: 0.0 ± 0.0
2.176HisTyr: 2.176 ± 0.831
0.0HisXaa: 0.0 ± 0.0
Ile
4.352IleAla: 4.352 ± 1.038
1.554IleCys: 1.554 ± 0.385
1.865IleAsp: 1.865 ± 0.53
1.865IleGlu: 1.865 ± 0.765
1.554IlePhe: 1.554 ± 0.787
3.73IleGly: 3.73 ± 0.857
1.554IleHis: 1.554 ± 0.787
3.108IleIle: 3.108 ± 0.249
3.73IleLys: 3.73 ± 1.889
4.352IleLeu: 4.352 ± 1.319
2.176IleMet: 2.176 ± 0.659
2.798IleAsn: 2.798 ± 1.417
2.798IlePro: 2.798 ± 1.025
3.108IleGln: 3.108 ± 0.249
1.243IleArg: 1.243 ± 0.63
5.284IleSer: 5.284 ± 1.489
6.839IleThr: 6.839 ± 1.558
4.663IleVal: 4.663 ± 1.057
0.311IleTrp: 0.311 ± 0.412
2.176IleTyr: 2.176 ± 0.659
0.0IleXaa: 0.0 ± 0.0
Lys
4.041LysAla: 4.041 ± 0.11
0.622LysCys: 0.622 ± 0.315
3.108LysAsp: 3.108 ± 0.249
4.041LysGlu: 4.041 ± 0.11
2.487LysPhe: 2.487 ± 1.26
4.041LysGly: 4.041 ± 1.59
1.865LysHis: 1.865 ± 0.945
5.595LysIle: 5.595 ± 1.918
4.974LysLys: 4.974 ± 1.968
4.352LysLeu: 4.352 ± 0.585
0.622LysMet: 0.622 ± 0.315
2.176LysAsn: 2.176 ± 1.88
4.352LysPro: 4.352 ± 0.049
3.73LysGln: 3.73 ± 0.321
3.73LysArg: 3.73 ± 0.845
3.73LysSer: 3.73 ± 1.197
4.974LysThr: 4.974 ± 0.883
3.108LysVal: 3.108 ± 0.249
0.0LysTrp: 0.0 ± 0.0
2.176LysTyr: 2.176 ± 0.61
0.0LysXaa: 0.0 ± 0.0
Leu
5.284LeuAla: 5.284 ± 0.52
1.554LeuCys: 1.554 ± 0.385
3.108LeuAsp: 3.108 ± 0.741
4.352LeuGlu: 4.352 ± 0.511
2.798LeuPhe: 2.798 ± 0.656
3.419LeuGly: 3.419 ± 1.491
3.419LeuHis: 3.419 ± 0.897
3.419LeuIle: 3.419 ± 1.266
4.663LeuLys: 4.663 ± 1.888
5.595LeuLeu: 5.595 ± 0.585
2.176LeuMet: 2.176 ± 2.404
4.041LeuAsn: 4.041 ± 2.06
2.487LeuPro: 2.487 ± 0.563
3.73LeuGln: 3.73 ± 2.031
3.108LeuArg: 3.108 ± 1.575
8.393LeuSer: 8.393 ± 2.255
8.082LeuThr: 8.082 ± 0.221
5.284LeuVal: 5.284 ± 1.573
0.622LeuTrp: 0.622 ± 0.315
4.041LeuTyr: 4.041 ± 0.11
0.0LeuXaa: 0.0 ± 0.0
Met
2.176MetAla: 2.176 ± 0.61
0.311MetCys: 0.311 ± 0.157
0.0MetAsp: 0.0 ± 0.0
1.865MetGlu: 1.865 ± 0.53
0.622MetPhe: 0.622 ± 0.3
2.176MetGly: 2.176 ± 1.466
0.0MetHis: 0.0 ± 0.0
0.311MetIle: 0.311 ± 0.157
1.243MetLys: 1.243 ± 0.726
2.176MetLeu: 2.176 ± 2.404
0.622MetMet: 0.622 ± 0.811
1.243MetAsn: 1.243 ± 0.723
1.243MetPro: 1.243 ± 0.63
2.176MetGln: 2.176 ± 0.482
0.622MetArg: 0.622 ± 0.3
2.798MetSer: 2.798 ± 1.417
1.554MetThr: 1.554 ± 0.615
0.933MetVal: 0.933 ± 0.245
0.0MetTrp: 0.0 ± 0.0
0.622MetTyr: 0.622 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
3.108AsnAla: 3.108 ± 2.718
0.622AsnCys: 0.622 ± 0.315
1.554AsnAsp: 1.554 ± 0.615
4.041AsnGlu: 4.041 ± 1.001
3.73AsnPhe: 3.73 ± 0.799
5.284AsnGly: 5.284 ± 1.036
0.622AsnHis: 0.622 ± 0.315
1.243AsnIle: 1.243 ± 0.63
4.352AsnLys: 4.352 ± 0.511
5.906AsnLeu: 5.906 ± 0.522
1.554AsnMet: 1.554 ± 0.91
1.554AsnAsn: 1.554 ± 0.787
2.798AsnPro: 2.798 ± 1.593
2.487AsnGln: 2.487 ± 3.298
1.243AsnArg: 1.243 ± 0.723
3.108AsnSer: 3.108 ± 2.152
5.284AsnThr: 5.284 ± 1.792
2.798AsnVal: 2.798 ± 0.959
0.622AsnTrp: 0.622 ± 0.315
0.622AsnTyr: 0.622 ± 0.315
0.0AsnXaa: 0.0 ± 0.0
Pro
2.487ProAla: 2.487 ± 0.563
1.243ProCys: 1.243 ± 0.282
1.243ProAsp: 1.243 ± 0.282
4.352ProGlu: 4.352 ± 2.152
0.933ProPhe: 0.933 ± 0.245
1.554ProGly: 1.554 ± 1.001
1.554ProHis: 1.554 ± 0.385
6.217ProIle: 6.217 ± 1.833
0.622ProLys: 0.622 ± 0.315
4.041ProLeu: 4.041 ± 1.199
1.243ProMet: 1.243 ± 1.34
1.865ProAsn: 1.865 ± 0.765
3.419ProPro: 3.419 ± 1.266
1.865ProGln: 1.865 ± 0.945
1.243ProArg: 1.243 ± 0.723
5.595ProSer: 5.595 ± 1.281
6.217ProThr: 6.217 ± 1.408
3.419ProVal: 3.419 ± 1.003
0.311ProTrp: 0.311 ± 0.157
1.243ProTyr: 1.243 ± 0.601
0.0ProXaa: 0.0 ± 0.0
Gln
2.487GlnAla: 2.487 ± 2.306
0.0GlnCys: 0.0 ± 0.0
1.243GlnAsp: 1.243 ± 0.282
1.243GlnGlu: 1.243 ± 0.726
3.419GlnPhe: 3.419 ± 0.241
1.865GlnGly: 1.865 ± 0.517
2.176GlnHis: 2.176 ± 0.659
1.865GlnIle: 1.865 ± 0.53
4.041GlnLys: 4.041 ± 1.21
5.284GlnLeu: 5.284 ± 1.792
0.933GlnMet: 0.933 ± 1.7
3.73GlnAsn: 3.73 ± 1.53
1.243GlnPro: 1.243 ± 0.601
2.176GlnGln: 2.176 ± 0.831
2.487GlnArg: 2.487 ± 0.483
3.73GlnSer: 3.73 ± 1.517
4.352GlnThr: 4.352 ± 1.948
3.73GlnVal: 3.73 ± 0.321
0.622GlnTrp: 0.622 ± 0.315
1.554GlnTyr: 1.554 ± 0.727
0.0GlnXaa: 0.0 ± 0.0
Arg
2.176ArgAla: 2.176 ± 1.055
0.933ArgCys: 0.933 ± 0.245
3.108ArgAsp: 3.108 ± 0.741
3.108ArgGlu: 3.108 ± 1.112
2.798ArgPhe: 2.798 ± 0.735
1.865ArgGly: 1.865 ± 0.901
1.554ArgHis: 1.554 ± 0.385
2.487ArgIle: 2.487 ± 0.563
3.108ArgLys: 3.108 ± 1.112
3.73ArgLeu: 3.73 ± 0.799
1.554ArgMet: 1.554 ± 0.385
2.798ArgAsn: 2.798 ± 1.336
1.865ArgPro: 1.865 ± 0.517
2.798ArgGln: 2.798 ± 0.959
4.352ArgArg: 4.352 ± 1.246
3.419ArgSer: 3.419 ± 0.425
3.108ArgThr: 3.108 ± 0.582
2.176ArgVal: 2.176 ± 0.82
0.622ArgTrp: 0.622 ± 0.825
2.487ArgTyr: 2.487 ± 0.483
0.0ArgXaa: 0.0 ± 0.0
Ser
5.595SerAla: 5.595 ± 2.555
0.311SerCys: 0.311 ± 0.157
5.284SerAsp: 5.284 ± 1.868
3.108SerGlu: 3.108 ± 1.102
4.041SerPhe: 4.041 ± 1.286
4.041SerGly: 4.041 ± 1.368
0.933SerHis: 0.933 ± 0.472
5.595SerIle: 5.595 ± 1.087
4.352SerLys: 4.352 ± 0.954
6.839SerLeu: 6.839 ± 0.941
1.243SerMet: 1.243 ± 0.726
2.487SerAsn: 2.487 ± 0.897
4.663SerPro: 4.663 ± 1.888
2.176SerGln: 2.176 ± 1.055
3.419SerArg: 3.419 ± 1.204
6.839SerSer: 6.839 ± 1.185
5.595SerThr: 5.595 ± 2.159
4.041SerVal: 4.041 ± 0.652
0.311SerTrp: 0.311 ± 0.157
3.419SerTyr: 3.419 ± 0.897
0.0SerXaa: 0.0 ± 0.0
Thr
8.704ThrAla: 8.704 ± 2.802
0.622ThrCys: 0.622 ± 0.315
3.419ThrAsp: 3.419 ± 0.779
3.108ThrGlu: 3.108 ± 1.502
3.73ThrPhe: 3.73 ± 2.028
5.906ThrGly: 5.906 ± 3.113
2.176ThrHis: 2.176 ± 0.61
4.663ThrIle: 4.663 ± 1.823
4.041ThrLys: 4.041 ± 0.981
6.217ThrLeu: 6.217 ± 1.54
0.933ThrMet: 0.933 ± 0.472
4.352ThrAsn: 4.352 ± 0.511
5.284ThrPro: 5.284 ± 1.243
4.974ThrGln: 4.974 ± 1.751
5.595ThrArg: 5.595 ± 0.585
5.906ThrSer: 5.906 ± 0.835
4.352ThrThr: 4.352 ± 1.732
5.595ThrVal: 5.595 ± 1.55
0.311ThrTrp: 0.311 ± 0.157
3.73ThrTyr: 3.73 ± 0.98
0.0ThrXaa: 0.0 ± 0.0
Val
2.798ValAla: 2.798 ± 0.74
0.933ValCys: 0.933 ± 0.245
5.284ValAsp: 5.284 ± 1.243
2.798ValGlu: 2.798 ± 0.656
2.798ValPhe: 2.798 ± 1.117
3.108ValGly: 3.108 ± 0.741
2.798ValHis: 2.798 ± 1.417
2.798ValIle: 2.798 ± 0.656
5.906ValLys: 5.906 ± 1.337
4.663ValLeu: 4.663 ± 1.888
2.176ValMet: 2.176 ± 0.557
2.798ValAsn: 2.798 ± 0.341
3.419ValPro: 3.419 ± 1.204
2.487ValGln: 2.487 ± 1.26
2.798ValArg: 2.798 ± 1.417
2.798ValSer: 2.798 ± 0.74
4.974ValThr: 4.974 ± 1.224
4.041ValVal: 4.041 ± 0.981
0.0ValTrp: 0.0 ± 0.0
1.554ValTyr: 1.554 ± 0.385
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.622TrpAsp: 0.622 ± 0.315
0.622TrpGlu: 0.622 ± 0.315
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.311TrpHis: 0.311 ± 0.157
0.0TrpIle: 0.0 ± 0.0
0.311TrpLys: 0.311 ± 0.157
0.622TrpLeu: 0.622 ± 0.315
0.311TrpMet: 0.311 ± 0.157
0.933TrpAsn: 0.933 ± 0.245
0.311TrpPro: 0.311 ± 0.412
0.622TrpGln: 0.622 ± 0.825
0.622TrpArg: 0.622 ± 0.825
0.311TrpSer: 0.311 ± 0.157
0.311TrpThr: 0.311 ± 0.157
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.311TrpTyr: 0.311 ± 0.412
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.798TyrAla: 2.798 ± 1.417
0.311TyrCys: 0.311 ± 0.412
2.798TyrAsp: 2.798 ± 0.341
1.554TyrGlu: 1.554 ± 0.525
0.311TyrPhe: 0.311 ± 0.412
2.176TyrGly: 2.176 ± 0.82
1.243TyrHis: 1.243 ± 0.282
2.176TyrIle: 2.176 ± 0.482
1.865TyrLys: 1.865 ± 0.517
4.041TyrLeu: 4.041 ± 1.368
0.622TyrMet: 0.622 ± 0.315
1.554TyrAsn: 1.554 ± 0.385
1.554TyrPro: 1.554 ± 0.525
1.554TyrGln: 1.554 ± 0.727
2.487TyrArg: 2.487 ± 0.808
1.554TyrSer: 1.554 ± 0.615
5.595TyrThr: 5.595 ± 1.013
1.865TyrVal: 1.865 ± 0.517
0.311TyrTrp: 0.311 ± 0.412
0.933TyrTyr: 0.933 ± 0.245
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3218 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski