Amino acid dipepetide frequency for Tessaracoccus flavus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.281AlaAla: 17.281 ± 0.229	0.898AlaCys: 0.898 ± 0.034	8.036AlaAsp: 8.036 ± 0.119	8.17AlaGlu: 8.17 ± 0.13	3.483AlaPhe: 3.483 ± 0.068	10.858AlaGly: 10.858 ± 0.138	2.401AlaHis: 2.401 ± 0.061	5.149AlaIle: 5.149 ± 0.081	3.052AlaLys: 3.052 ± 0.076	13.058AlaLeu: 13.058 ± 0.17	2.761AlaMet: 2.761 ± 0.068	2.405AlaAsn: 2.405 ± 0.056	5.657AlaPro: 5.657 ± 0.102	3.768AlaGln: 3.768 ± 0.071	8.264AlaArg: 8.264 ± 0.138	6.646AlaSer: 6.646 ± 0.092	7.241AlaThr: 7.241 ± 0.118	10.602AlaVal: 10.602 ± 0.134	1.855AlaTrp: 1.855 ± 0.048	2.331AlaTyr: 2.331 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.757CysAla: 0.757 ± 0.03	0.076CysCys: 0.076 ± 0.011	0.434CysAsp: 0.434 ± 0.02	0.388CysGlu: 0.388 ± 0.022	0.189CysPhe: 0.189 ± 0.014	0.712CysGly: 0.712 ± 0.036	0.194CysHis: 0.194 ± 0.015	0.22CysIle: 0.22 ± 0.018	0.1CysLys: 0.1 ± 0.01	0.637CysLeu: 0.637 ± 0.027	0.109CysMet: 0.109 ± 0.012	0.149CysAsn: 0.149 ± 0.012	0.46CysPro: 0.46 ± 0.027	0.198CysGln: 0.198 ± 0.016	0.532CysArg: 0.532 ± 0.027	0.396CysSer: 0.396 ± 0.022	0.418CysThr: 0.418 ± 0.022	0.538CysVal: 0.538 ± 0.024	0.093CysTrp: 0.093 ± 0.01	0.148CysTyr: 0.148 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.588AspAla: 7.588 ± 0.107	0.35AspCys: 0.35 ± 0.021	4.747AspAsp: 4.747 ± 0.098	4.744AspGlu: 4.744 ± 0.089	1.846AspPhe: 1.846 ± 0.044	6.52AspGly: 6.52 ± 0.119	1.407AspHis: 1.407 ± 0.04	2.329AspIle: 2.329 ± 0.055	1.265AspLys: 1.265 ± 0.044	6.674AspLeu: 6.674 ± 0.096	0.934AspMet: 0.934 ± 0.033	1.127AspAsn: 1.127 ± 0.038	4.365AspPro: 4.365 ± 0.077	1.896AspGln: 1.896 ± 0.054	4.218AspArg: 4.218 ± 0.075	2.698AspSer: 2.698 ± 0.051	2.947AspThr: 2.947 ± 0.08	5.597AspVal: 5.597 ± 0.08	0.997AspTrp: 0.997 ± 0.034	1.337AspTyr: 1.337 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.447GluAla: 7.447 ± 0.13	0.401GluCys: 0.401 ± 0.022	2.905GluAsp: 2.905 ± 0.061	3.386GluGlu: 3.386 ± 0.068	1.904GluPhe: 1.904 ± 0.044	4.585GluGly: 4.585 ± 0.074	1.438GluHis: 1.438 ± 0.044	2.818GluIle: 2.818 ± 0.056	1.398GluLys: 1.398 ± 0.048	6.892GluLeu: 6.892 ± 0.096	1.204GluMet: 1.204 ± 0.035	1.048GluAsn: 1.048 ± 0.037	3.307GluPro: 3.307 ± 0.082	2.25GluGln: 2.25 ± 0.055	4.956GluArg: 4.956 ± 0.089	2.962GluSer: 2.962 ± 0.065	3.039GluThr: 3.039 ± 0.062	5.172GluVal: 5.172 ± 0.081	0.861GluTrp: 0.861 ± 0.035	1.112GluTyr: 1.112 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.755PheAla: 3.755 ± 0.068	0.233PheCys: 0.233 ± 0.016	2.371PheAsp: 2.371 ± 0.049	1.787PheGlu: 1.787 ± 0.04	1.021PhePhe: 1.021 ± 0.046	3.189PheGly: 3.189 ± 0.073	0.647PheHis: 0.647 ± 0.028	1.244PheIle: 1.244 ± 0.038	0.608PheLys: 0.608 ± 0.03	2.849PheLeu: 2.849 ± 0.065	0.56PheMet: 0.56 ± 0.026	0.873PheAsn: 0.873 ± 0.039	1.394PhePro: 1.394 ± 0.035	0.757PheGln: 0.757 ± 0.029	1.799PheArg: 1.799 ± 0.042	1.808PheSer: 1.808 ± 0.046	2.035PheThr: 2.035 ± 0.06	2.78PheVal: 2.78 ± 0.053	0.466PheTrp: 0.466 ± 0.024	0.643PheTyr: 0.643 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.608GlyAla: 9.608 ± 0.114	0.72GlyCys: 0.72 ± 0.034	5.272GlyAsp: 5.272 ± 0.099	5.161GlyGlu: 5.161 ± 0.075	3.167GlyPhe: 3.167 ± 0.065	7.169GlyGly: 7.169 ± 0.15	2.003GlyHis: 2.003 ± 0.049	4.133GlyIle: 4.133 ± 0.08	2.319GlyLys: 2.319 ± 0.06	9.289GlyLeu: 9.289 ± 0.12	2.145GlyMet: 2.145 ± 0.05	1.967GlyAsn: 1.967 ± 0.067	3.873GlyPro: 3.873 ± 0.062	2.822GlyGln: 2.822 ± 0.061	6.5GlyArg: 6.5 ± 0.095	5.248GlySer: 5.248 ± 0.14	5.322GlyThr: 5.322 ± 0.147	7.725GlyVal: 7.725 ± 0.096	1.803GlyTrp: 1.803 ± 0.049	2.243GlyTyr: 2.243 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	2.212HisAla: 2.212 ± 0.048	0.171HisCys: 0.171 ± 0.014	1.394HisAsp: 1.394 ± 0.037	1.241HisGlu: 1.241 ± 0.035	0.603HisPhe: 0.603 ± 0.028	1.977HisGly: 1.977 ± 0.05	0.631HisHis: 0.631 ± 0.025	0.758HisIle: 0.758 ± 0.027	0.375HisLys: 0.375 ± 0.019	2.3HisLeu: 2.3 ± 0.05	0.385HisMet: 0.385 ± 0.023	0.471HisAsn: 0.471 ± 0.023	1.528HisPro: 1.528 ± 0.045	0.65HisGln: 0.65 ± 0.027	1.744HisArg: 1.744 ± 0.049	1.031HisSer: 1.031 ± 0.038	1.165HisThr: 1.165 ± 0.043	1.747HisVal: 1.747 ± 0.041	0.292HisTrp: 0.292 ± 0.019	0.486HisTyr: 0.486 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.844IleAla: 5.844 ± 0.088	0.32IleCys: 0.32 ± 0.018	3.337IleAsp: 3.337 ± 0.066	2.841IleGlu: 2.841 ± 0.065	1.166IlePhe: 1.166 ± 0.04	4.061IleGly: 4.061 ± 0.07	0.81IleHis: 0.81 ± 0.033	1.856IleIle: 1.856 ± 0.06	0.863IleLys: 0.863 ± 0.036	3.555IleLeu: 3.555 ± 0.08	0.71IleMet: 0.71 ± 0.025	1.131IleAsn: 1.131 ± 0.041	2.139IlePro: 2.139 ± 0.049	1.03IleGln: 1.03 ± 0.037	2.598IleArg: 2.598 ± 0.054	2.416IleSer: 2.416 ± 0.069	2.76IleThr: 2.76 ± 0.081	4.035IleVal: 4.035 ± 0.081	0.559IleTrp: 0.559 ± 0.024	0.876IleTyr: 0.876 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	2.805LysAla: 2.805 ± 0.073	0.112LysCys: 0.112 ± 0.011	1.15LysAsp: 1.15 ± 0.039	1.15LysGlu: 1.15 ± 0.046	0.655LysPhe: 0.655 ± 0.029	1.765LysGly: 1.765 ± 0.047	0.459LysHis: 0.459 ± 0.022	0.965LysIle: 0.965 ± 0.032	0.826LysLys: 0.826 ± 0.042	2.307LysLeu: 2.307 ± 0.051	0.49LysMet: 0.49 ± 0.027	0.469LysAsn: 0.469 ± 0.026	1.288LysPro: 1.288 ± 0.048	0.735LysGln: 0.735 ± 0.033	1.629LysArg: 1.629 ± 0.05	1.233LysSer: 1.233 ± 0.036	1.367LysThr: 1.367 ± 0.045	2.032LysVal: 2.032 ± 0.057	0.299LysTrp: 0.299 ± 0.016	0.489LysTyr: 0.489 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	13.939LeuAla: 13.939 ± 0.173	0.607LeuCys: 0.607 ± 0.028	6.755LeuAsp: 6.755 ± 0.084	5.215LeuGlu: 5.215 ± 0.083	2.828LeuPhe: 2.828 ± 0.062	9.534LeuGly: 9.534 ± 0.116	1.962LeuHis: 1.962 ± 0.055	4.426LeuIle: 4.426 ± 0.087	2.087LeuLys: 2.087 ± 0.056	9.968LeuLeu: 9.968 ± 0.151	1.937LeuMet: 1.937 ± 0.052	2.241LeuAsn: 2.241 ± 0.057	5.7LeuPro: 5.7 ± 0.085	2.605LeuGln: 2.605 ± 0.048	7.583LeuArg: 7.583 ± 0.114	5.961LeuSer: 5.961 ± 0.095	6.925LeuThr: 6.925 ± 0.135	8.946LeuVal: 8.946 ± 0.134	1.334LeuTrp: 1.334 ± 0.049	1.719LeuTyr: 1.719 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.651MetAla: 2.651 ± 0.067	0.127MetCys: 0.127 ± 0.013	0.987MetAsp: 0.987 ± 0.035	0.877MetGlu: 0.877 ± 0.038	0.599MetPhe: 0.599 ± 0.025	1.635MetGly: 1.635 ± 0.048	0.38MetHis: 0.38 ± 0.02	0.943MetIle: 0.943 ± 0.038	0.556MetLys: 0.556 ± 0.027	2.04MetLeu: 2.04 ± 0.06	0.415MetMet: 0.415 ± 0.024	0.577MetAsn: 0.577 ± 0.028	1.168MetPro: 1.168 ± 0.044	0.574MetGln: 0.574 ± 0.023	1.49MetArg: 1.49 ± 0.041	1.504MetSer: 1.504 ± 0.042	1.676MetThr: 1.676 ± 0.041	1.656MetVal: 1.656 ± 0.043	0.263MetTrp: 0.263 ± 0.017	0.309MetTyr: 0.309 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.426AsnAla: 2.426 ± 0.052	0.165AsnCys: 0.165 ± 0.015	1.287AsnAsp: 1.287 ± 0.043	1.067AsnGlu: 1.067 ± 0.03	0.684AsnPhe: 0.684 ± 0.027	1.909AsnGly: 1.909 ± 0.062	0.497AsnHis: 0.497 ± 0.024	0.922AsnIle: 0.922 ± 0.037	0.483AsnLys: 0.483 ± 0.028	2.186AsnLeu: 2.186 ± 0.054	0.407AsnMet: 0.407 ± 0.023	0.615AsnAsn: 0.615 ± 0.034	1.703AsnPro: 1.703 ± 0.046	0.663AsnGln: 0.663 ± 0.028	1.433AsnArg: 1.433 ± 0.045	1.134AsnSer: 1.134 ± 0.039	1.19AsnThr: 1.19 ± 0.051	1.765AsnVal: 1.765 ± 0.049	0.353AsnTrp: 0.353 ± 0.02	0.602AsnTyr: 0.602 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	6.534ProAla: 6.534 ± 0.094	0.259ProCys: 0.259 ± 0.017	4.138ProAsp: 4.138 ± 0.081	3.964ProGlu: 3.964 ± 0.072	1.515ProPhe: 1.515 ± 0.044	5.191ProGly: 5.191 ± 0.082	1.178ProHis: 1.178 ± 0.035	2.054ProIle: 2.054 ± 0.042	1.178ProLys: 1.178 ± 0.038	4.876ProLeu: 4.876 ± 0.08	1.104ProMet: 1.104 ± 0.037	1.177ProAsn: 1.177 ± 0.041	2.542ProPro: 2.542 ± 0.076	1.568ProGln: 1.568 ± 0.04	3.215ProArg: 3.215 ± 0.081	3.538ProSer: 3.538 ± 0.088	3.723ProThr: 3.723 ± 0.096	4.58ProVal: 4.58 ± 0.079	0.817ProTrp: 0.817 ± 0.038	1.062ProTyr: 1.062 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.671GlnAla: 3.671 ± 0.07	0.16GlnCys: 0.16 ± 0.014	1.325GlnAsp: 1.325 ± 0.04	1.52GlnGlu: 1.52 ± 0.041	0.908GlnPhe: 0.908 ± 0.032	2.292GlnGly: 2.292 ± 0.049	0.632GlnHis: 0.632 ± 0.029	1.389GlnIle: 1.389 ± 0.047	0.623GlnLys: 0.623 ± 0.029	3.512GlnLeu: 3.512 ± 0.067	0.632GlnMet: 0.632 ± 0.028	0.522GlnAsn: 0.522 ± 0.022	1.834GlnPro: 1.834 ± 0.05	1.284GlnGln: 1.284 ± 0.049	2.612GlnArg: 2.612 ± 0.058	1.51GlnSer: 1.51 ± 0.042	1.567GlnThr: 1.567 ± 0.045	2.616GlnVal: 2.616 ± 0.058	0.569GlnTrp: 0.569 ± 0.029	0.612GlnTyr: 0.612 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	8.088ArgAla: 8.088 ± 0.117	0.485ArgCys: 0.485 ± 0.026	4.312ArgAsp: 4.312 ± 0.08	4.294ArgGlu: 4.294 ± 0.095	2.334ArgPhe: 2.334 ± 0.054	5.196ArgGly: 5.196 ± 0.088	1.667ArgHis: 1.667 ± 0.049	3.372ArgIle: 3.372 ± 0.064	1.514ArgLys: 1.514 ± 0.052	7.412ArgLeu: 7.412 ± 0.118	1.751ArgMet: 1.751 ± 0.042	1.494ArgAsn: 1.494 ± 0.041	3.807ArgPro: 3.807 ± 0.088	2.368ArgGln: 2.368 ± 0.054	6.573ArgArg: 6.573 ± 0.142	4.034ArgSer: 4.034 ± 0.081	3.998ArgThr: 3.998 ± 0.064	5.709ArgVal: 5.709 ± 0.093	1.283ArgTrp: 1.283 ± 0.044	1.72ArgTyr: 1.72 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.575SerAla: 6.575 ± 0.089	0.407SerCys: 0.407 ± 0.021	3.284SerAsp: 3.284 ± 0.066	2.912SerGlu: 2.912 ± 0.06	1.983SerPhe: 1.983 ± 0.056	5.58SerGly: 5.58 ± 0.145	1.113SerHis: 1.113 ± 0.034	2.35SerIle: 2.35 ± 0.056	1.193SerLys: 1.193 ± 0.042	5.607SerLeu: 5.607 ± 0.095	1.358SerMet: 1.358 ± 0.047	1.197SerAsn: 1.197 ± 0.035	3.239SerPro: 3.239 ± 0.076	1.525SerGln: 1.525 ± 0.037	3.794SerArg: 3.794 ± 0.077	3.403SerSer: 3.403 ± 0.079	3.384SerThr: 3.384 ± 0.072	4.831SerVal: 4.831 ± 0.095	0.98SerTrp: 0.98 ± 0.036	1.373SerTyr: 1.373 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	7.11ThrAla: 7.11 ± 0.137	0.399ThrCys: 0.399 ± 0.024	3.71ThrAsp: 3.71 ± 0.076	3.06ThrGlu: 3.06 ± 0.054	1.995ThrPhe: 1.995 ± 0.074	5.597ThrGly: 5.597 ± 0.16	1.213ThrHis: 1.213 ± 0.04	2.762ThrIle: 2.762 ± 0.075	1.2ThrLys: 1.2 ± 0.041	6.11ThrLeu: 6.11 ± 0.136	1.298ThrMet: 1.298 ± 0.039	1.314ThrAsn: 1.314 ± 0.043	3.956ThrPro: 3.956 ± 0.082	1.659ThrGln: 1.659 ± 0.047	3.642ThrArg: 3.642 ± 0.077	3.458ThrSer: 3.458 ± 0.07	4.06ThrThr: 4.06 ± 0.111	5.921ThrVal: 5.921 ± 0.144	0.957ThrTrp: 0.957 ± 0.037	1.372ThrTyr: 1.372 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	11.531ValAla: 11.531 ± 0.146	0.593ValCys: 0.593 ± 0.03	5.987ValAsp: 5.987 ± 0.074	5.317ValGlu: 5.317 ± 0.078	2.612ValPhe: 2.612 ± 0.058	7.666ValGly: 7.666 ± 0.107	1.737ValHis: 1.737 ± 0.047	3.921ValIle: 3.921 ± 0.063	1.873ValLys: 1.873 ± 0.055	8.79ValLeu: 8.79 ± 0.108	1.625ValMet: 1.625 ± 0.046	1.86ValAsn: 1.86 ± 0.051	4.37ValPro: 4.37 ± 0.066	2.18ValGln: 2.18 ± 0.055	5.73ValArg: 5.73 ± 0.073	4.941ValSer: 4.941 ± 0.086	5.829ValThr: 5.829 ± 0.133	8.943ValVal: 8.943 ± 0.142	1.198ValTrp: 1.198 ± 0.044	1.479ValTyr: 1.479 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.819TrpAla: 1.819 ± 0.053	0.112TrpCys: 0.112 ± 0.011	0.777TrpAsp: 0.777 ± 0.03	0.759TrpGlu: 0.759 ± 0.027	0.566TrpPhe: 0.566 ± 0.027	1.179TrpGly: 1.179 ± 0.039	0.355TrpHis: 0.355 ± 0.02	0.611TrpIle: 0.611 ± 0.024	0.325TrpLys: 0.325 ± 0.019	1.882TrpLeu: 1.882 ± 0.058	0.33TrpMet: 0.33 ± 0.021	0.35TrpAsn: 0.35 ± 0.021	0.782TrpPro: 0.782 ± 0.03	0.615TrpGln: 0.615 ± 0.027	1.392TrpArg: 1.392 ± 0.046	0.964TrpSer: 0.964 ± 0.039	0.968TrpThr: 0.968 ± 0.038	1.267TrpVal: 1.267 ± 0.04	0.339TrpTrp: 0.339 ± 0.021	0.29TrpTyr: 0.29 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.271TyrAla: 2.271 ± 0.047	0.155TyrCys: 0.155 ± 0.012	1.378TyrAsp: 1.378 ± 0.043	1.233TyrGlu: 1.233 ± 0.038	0.761TyrPhe: 0.761 ± 0.028	1.875TyrGly: 1.875 ± 0.048	0.436TyrHis: 0.436 ± 0.022	0.685TyrIle: 0.685 ± 0.026	0.39TyrLys: 0.39 ± 0.022	2.327TyrLeu: 2.327 ± 0.057	0.27TyrMet: 0.27 ± 0.021	0.503TyrAsn: 0.503 ± 0.029	1.1TyrPro: 1.1 ± 0.041	0.646TyrGln: 0.646 ± 0.025	1.704TyrArg: 1.704 ± 0.046	1.204TyrSer: 1.204 ± 0.037	1.179TyrThr: 1.179 ± 0.045	1.722TyrVal: 1.722 ± 0.04	0.363TyrTrp: 0.363 ± 0.018	0.523TyrTyr: 0.523 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2784 proteins (923675 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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