Amino acid dipepetide frequency for Bodo saltans virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.896AlaAla: 3.896 ± 0.283
0.793AlaCys: 0.793 ± 0.05
1.317AlaAsp: 1.317 ± 0.066
2.126AlaGlu: 2.126 ± 0.09
1.434AlaPhe: 1.434 ± 0.076
1.147AlaGly: 1.147 ± 0.068
2.87AlaHis: 2.87 ± 0.208
3.555AlaIle: 3.555 ± 0.291
3.281AlaLys: 3.281 ± 0.109
2.834AlaLeu: 2.834 ± 0.221
0.772AlaMet: 0.772 ± 0.047
2.534AlaAsn: 2.534 ± 0.139
0.904AlaPro: 0.904 ± 0.103
1.346AlaGln: 1.346 ± 0.072
1.286AlaArg: 1.286 ± 0.072
2.16AlaSer: 2.16 ± 0.1
1.741AlaThr: 1.741 ± 0.133
1.56AlaVal: 1.56 ± 0.143
0.269AlaTrp: 0.269 ± 0.028
1.79AlaTyr: 1.79 ± 0.079
0.0AlaXaa: 0.0 ± 0.0
Cys
1.15CysAla: 1.15 ± 0.075
0.827CysCys: 0.827 ± 0.098
1.602CysAsp: 1.602 ± 0.081
1.648CysGlu: 1.648 ± 0.081
1.32CysPhe: 1.32 ± 0.063
1.031CysGly: 1.031 ± 0.056
0.93CysHis: 0.93 ± 0.073
2.289CysIle: 2.289 ± 0.104
2.48CysLys: 2.48 ± 0.137
5.123CysLeu: 5.123 ± 0.318
0.439CysMet: 0.439 ± 0.032
1.829CysAsn: 1.829 ± 0.098
2.495CysPro: 2.495 ± 0.187
0.517CysGln: 0.517 ± 0.045
0.863CysArg: 0.863 ± 0.062
2.222CysSer: 2.222 ± 0.109
1.152CysThr: 1.152 ± 0.062
1.082CysVal: 1.082 ± 0.064
0.139CysTrp: 0.139 ± 0.02
1.09CysTyr: 1.09 ± 0.059
0.0CysXaa: 0.0 ± 0.0
Asp
1.927AspAla: 1.927 ± 0.081
1.653AspCys: 1.653 ± 0.09
5.363AspAsp: 5.363 ± 0.249
5.239AspGlu: 5.239 ± 0.17
2.994AspPhe: 2.994 ± 0.089
2.227AspGly: 2.227 ± 0.08
0.708AspHis: 0.708 ± 0.06
6.246AspIle: 6.246 ± 0.194
6.993AspLys: 6.993 ± 0.188
4.19AspLeu: 4.19 ± 0.109
1.403AspMet: 1.403 ± 0.064
6.386AspAsn: 6.386 ± 0.298
1.028AspPro: 1.028 ± 0.059
0.816AspGln: 0.816 ± 0.062
1.183AspArg: 1.183 ± 0.071
3.728AspSer: 3.728 ± 0.16
3.436AspThr: 3.436 ± 0.149
2.617AspVal: 2.617 ± 0.089
0.687AspTrp: 0.687 ± 0.048
3.007AspTyr: 3.007 ± 0.164
0.0AspXaa: 0.0 ± 0.0
Glu
1.23GluAla: 1.23 ± 0.059
4.133GluCys: 4.133 ± 0.269
2.798GluAsp: 2.798 ± 0.135
3.508GluGlu: 3.508 ± 0.155
3.167GluPhe: 3.167 ± 0.101
1.206GluGly: 1.206 ± 0.078
1.454GluHis: 1.454 ± 0.073
6.812GluIle: 6.812 ± 0.258
8.127GluLys: 8.127 ± 0.269
5.941GluLeu: 5.941 ± 0.139
1.775GluMet: 1.775 ± 0.069
10.106GluAsn: 10.106 ± 0.382
1.162GluPro: 1.162 ± 0.088
2.532GluGln: 2.532 ± 0.127
1.994GluArg: 1.994 ± 0.116
3.268GluSer: 3.268 ± 0.124
2.896GluThr: 2.896 ± 0.108
1.248GluVal: 1.248 ± 0.067
0.61GluTrp: 0.61 ± 0.043
3.746GluTyr: 3.746 ± 0.135
0.0GluXaa: 0.0 ± 0.0
Phe
2.152PheAla: 2.152 ± 0.095
1.002PheCys: 1.002 ± 0.055
3.815PheAsp: 3.815 ± 0.1
3.482PheGlu: 3.482 ± 0.103
2.012PhePhe: 2.012 ± 0.084
2.209PheGly: 2.209 ± 0.087
0.744PheHis: 0.744 ± 0.042
4.59PheIle: 4.59 ± 0.117
3.332PheLys: 3.332 ± 0.108
3.082PheLeu: 3.082 ± 0.115
1.212PheMet: 1.212 ± 0.068
3.981PheAsn: 3.981 ± 0.105
1.235PhePro: 1.235 ± 0.057
0.803PheGln: 0.803 ± 0.052
1.206PheArg: 1.206 ± 0.062
2.852PheSer: 2.852 ± 0.098
2.42PheThr: 2.42 ± 0.095
2.439PheVal: 2.439 ± 0.081
0.318PheTrp: 0.318 ± 0.035
2.508PheTyr: 2.508 ± 0.097
0.0PheXaa: 0.0 ± 0.0
Gly
1.217GlyAla: 1.217 ± 0.104
3.834GlyCys: 3.834 ± 0.277
1.87GlyAsp: 1.87 ± 0.107
2.005GlyGlu: 2.005 ± 0.091
1.723GlyPhe: 1.723 ± 0.088
1.87GlyGly: 1.87 ± 0.095
3.175GlyHis: 3.175 ± 0.229
2.816GlyIle: 2.816 ± 0.108
3.635GlyLys: 3.635 ± 0.119
2.389GlyLeu: 2.389 ± 0.099
0.757GlyMet: 0.757 ± 0.066
3.381GlyAsn: 3.381 ± 0.431
0.183GlyPro: 0.183 ± 0.028
1.418GlyGln: 1.418 ± 0.114
0.992GlyArg: 0.992 ± 0.059
2.188GlySer: 2.188 ± 0.208
2.242GlyThr: 2.242 ± 0.397
1.501GlyVal: 1.501 ± 0.078
0.3GlyTrp: 0.3 ± 0.03
2.255GlyTyr: 2.255 ± 0.163
0.0GlyXaa: 0.0 ± 0.0
His
0.656HisAla: 0.656 ± 0.037
0.602HisCys: 0.602 ± 0.113
1.188HisAsp: 1.188 ± 0.073
3.89HisGlu: 3.89 ± 0.23
0.976HisPhe: 0.976 ± 0.054
0.814HisGly: 0.814 ± 0.048
0.434HisHis: 0.434 ± 0.037
1.852HisIle: 1.852 ± 0.087
1.922HisLys: 1.922 ± 0.091
3.764HisLeu: 3.764 ± 0.231
0.511HisMet: 0.511 ± 0.053
1.803HisAsn: 1.803 ± 0.084
0.462HisPro: 0.462 ± 0.038
0.519HisGln: 0.519 ± 0.044
0.475HisArg: 0.475 ± 0.041
0.943HisSer: 0.943 ± 0.048
1.188HisThr: 1.188 ± 0.055
0.816HisVal: 0.816 ± 0.06
0.581HisTrp: 0.581 ± 0.062
0.982HisTyr: 0.982 ± 0.052
0.0HisXaa: 0.0 ± 0.0
Ile
3.557IleAla: 3.557 ± 0.124
2.47IleCys: 2.47 ± 0.083
7.189IleAsp: 7.189 ± 0.307
6.957IleGlu: 6.957 ± 0.166
4.652IlePhe: 4.652 ± 0.127
3.803IleGly: 3.803 ± 0.352
1.999IleHis: 1.999 ± 0.086
10.16IleIle: 10.16 ± 0.263
9.01IleLys: 9.01 ± 0.228
7.401IleLeu: 7.401 ± 0.197
2.532IleMet: 2.532 ± 0.089
8.55IleAsn: 8.55 ± 0.186
2.991IlePro: 2.991 ± 0.132
2.666IleGln: 2.666 ± 0.09
2.493IleArg: 2.493 ± 0.078
5.319IleSer: 5.319 ± 0.131
5.319IleThr: 5.319 ± 0.202
4.451IleVal: 4.451 ± 0.124
0.576IleTrp: 0.576 ± 0.046
4.335IleTyr: 4.335 ± 0.134
0.0IleXaa: 0.0 ± 0.0
Lys
1.772LysAla: 1.772 ± 0.083
2.712LysCys: 2.712 ± 0.133
4.779LysAsp: 4.779 ± 0.138
6.494LysGlu: 6.494 ± 0.274
4.58LysPhe: 4.58 ± 0.125
2.374LysGly: 2.374 ± 0.091
2.046LysHis: 2.046 ± 0.097
11.377LysIle: 11.377 ± 0.29
11.898LysLys: 11.898 ± 0.328
7.757LysLeu: 7.757 ± 0.195
2.578LysMet: 2.578 ± 0.092
11.072LysAsn: 11.072 ± 0.252
1.64LysPro: 1.64 ± 0.077
3.177LysGln: 3.177 ± 0.112
2.596LysArg: 2.596 ± 0.105
4.955LysSer: 4.955 ± 0.115
4.924LysThr: 4.924 ± 0.135
2.64LysVal: 2.64 ± 0.098
0.832LysTrp: 0.832 ± 0.055
9.708LysTyr: 9.708 ± 0.295
0.0LysXaa: 0.0 ± 0.0
Leu
2.234LeuAla: 2.234 ± 0.076
1.695LeuCys: 1.695 ± 0.085
3.955LeuAsp: 3.955 ± 0.152
6.641LeuGlu: 6.641 ± 0.225
4.094LeuPhe: 4.094 ± 0.105
2.356LeuGly: 2.356 ± 0.181
2.069LeuHis: 2.069 ± 0.089
6.688LeuIle: 6.688 ± 0.171
10.558LeuLys: 10.558 ± 0.304
6.151LeuLeu: 6.151 ± 0.193
1.702LeuMet: 1.702 ± 0.067
7.486LeuAsn: 7.486 ± 0.164
1.819LeuPro: 1.819 ± 0.09
3.195LeuGln: 3.195 ± 0.239
2.162LeuArg: 2.162 ± 0.09
4.955LeuSer: 4.955 ± 0.151
3.797LeuThr: 3.797 ± 0.112
2.56LeuVal: 2.56 ± 0.103
0.672LeuTrp: 0.672 ± 0.044
5.009LeuTyr: 5.009 ± 0.132
0.0LeuXaa: 0.0 ± 0.0
Met
0.664MetAla: 0.664 ± 0.046
0.457MetCys: 0.457 ± 0.034
1.224MetAsp: 1.224 ± 0.062
1.478MetGlu: 1.478 ± 0.081
1.075MetPhe: 1.075 ± 0.049
0.778MetGly: 0.778 ± 0.058
0.566MetHis: 0.566 ± 0.041
2.379MetIle: 2.379 ± 0.087
2.061MetLys: 2.061 ± 0.089
2.289MetLeu: 2.289 ± 0.076
0.726MetMet: 0.726 ± 0.052
2.134MetAsn: 2.134 ± 0.082
0.679MetPro: 0.679 ± 0.087
1.0MetGln: 1.0 ± 0.067
0.824MetArg: 0.824 ± 0.06
1.64MetSer: 1.64 ± 0.074
1.315MetThr: 1.315 ± 0.057
0.842MetVal: 0.842 ± 0.05
0.09MetTrp: 0.09 ± 0.017
1.307MetTyr: 1.307 ± 0.068
0.0MetXaa: 0.0 ± 0.0
Asn
3.508AsnAla: 3.508 ± 0.124
1.625AsnCys: 1.625 ± 0.083
7.122AsnAsp: 7.122 ± 0.179
6.993AsnGlu: 6.993 ± 0.203
3.945AsnPhe: 3.945 ± 0.136
8.946AsnGly: 8.946 ± 0.455
1.418AsnHis: 1.418 ± 0.078
10.217AsnIle: 10.217 ± 0.236
9.214AsnLys: 9.214 ± 0.232
6.386AsnLeu: 6.386 ± 0.193
2.552AsnMet: 2.552 ± 0.1
10.547AsnAsn: 10.547 ± 0.415
2.17AsnPro: 2.17 ± 0.091
2.24AsnGln: 2.24 ± 0.214
1.78AsnArg: 1.78 ± 0.082
4.668AsnSer: 4.668 ± 0.175
6.12AsnThr: 6.12 ± 0.883
3.996AsnVal: 3.996 ± 0.132
0.527AsnTrp: 0.527 ± 0.042
4.304AsnTyr: 4.304 ± 0.261
0.0AsnXaa: 0.0 ± 0.0
Pro
0.703ProAla: 0.703 ± 0.06
0.349ProCys: 0.349 ± 0.029
1.108ProAsp: 1.108 ± 0.059
1.558ProGlu: 1.558 ± 0.103
1.235ProPhe: 1.235 ± 0.055
0.535ProGly: 0.535 ± 0.04
0.411ProHis: 0.411 ± 0.035
2.16ProIle: 2.16 ± 0.082
2.539ProLys: 2.539 ± 0.133
1.718ProLeu: 1.718 ± 0.081
0.457ProMet: 0.457 ± 0.045
1.844ProAsn: 1.844 ± 0.101
0.767ProPro: 0.767 ± 0.082
0.935ProGln: 0.935 ± 0.068
0.511ProArg: 0.511 ± 0.045
1.658ProSer: 1.658 ± 0.101
1.576ProThr: 1.576 ± 0.108
1.103ProVal: 1.103 ± 0.087
1.78ProTrp: 1.78 ± 0.154
1.147ProTyr: 1.147 ± 0.065
0.0ProXaa: 0.0 ± 0.0
Gln
0.845GlnAla: 0.845 ± 0.154
0.517GlnCys: 0.517 ± 0.059
1.051GlnAsp: 1.051 ± 0.051
1.63GlnGlu: 1.63 ± 0.139
1.379GlnPhe: 1.379 ± 0.073
0.661GlnGly: 0.661 ± 0.101
0.708GlnHis: 0.708 ± 0.045
2.834GlnIle: 2.834 ± 0.114
2.942GlnLys: 2.942 ± 0.11
3.157GlnLeu: 3.157 ± 0.17
0.819GlnMet: 0.819 ± 0.058
3.4GlnAsn: 3.4 ± 0.152
0.863GlnPro: 0.863 ± 0.096
1.731GlnGln: 1.731 ± 0.148
0.855GlnArg: 0.855 ± 0.057
2.085GlnSer: 2.085 ± 0.23
1.55GlnThr: 1.55 ± 0.103
0.736GlnVal: 0.736 ± 0.065
0.253GlnTrp: 0.253 ± 0.03
2.245GlnTyr: 2.245 ± 0.093
0.0GlnXaa: 0.0 ± 0.0
Arg
0.894ArgAla: 0.894 ± 0.051
0.555ArgCys: 0.555 ± 0.044
1.519ArgAsp: 1.519 ± 0.067
2.064ArgGlu: 2.064 ± 0.089
1.157ArgPhe: 1.157 ± 0.05
0.997ArgGly: 0.997 ± 0.059
0.517ArgHis: 0.517 ± 0.039
2.361ArgIle: 2.361 ± 0.086
2.537ArgLys: 2.537 ± 0.105
1.723ArgLeu: 1.723 ± 0.081
0.674ArgMet: 0.674 ± 0.071
2.656ArgAsn: 2.656 ± 0.097
0.625ArgPro: 0.625 ± 0.041
0.984ArgGln: 0.984 ± 0.095
0.953ArgArg: 0.953 ± 0.053
1.067ArgSer: 1.067 ± 0.059
1.436ArgThr: 1.436 ± 0.077
0.94ArgVal: 0.94 ± 0.062
0.307ArgTrp: 0.307 ± 0.027
1.46ArgTyr: 1.46 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
2.188SerAla: 2.188 ± 0.109
1.064SerCys: 1.064 ± 0.055
3.883SerAsp: 3.883 ± 0.165
3.361SerGlu: 3.361 ± 0.123
2.643SerPhe: 2.643 ± 0.087
2.237SerGly: 2.237 ± 0.134
1.077SerHis: 1.077 ± 0.058
5.727SerIle: 5.727 ± 0.144
5.017SerLys: 5.017 ± 0.133
4.668SerLeu: 4.668 ± 0.193
1.392SerMet: 1.392 ± 0.112
5.585SerAsn: 5.585 ± 0.438
1.263SerPro: 1.263 ± 0.07
1.803SerGln: 1.803 ± 0.095
1.343SerArg: 1.343 ± 0.067
4.668SerSer: 4.668 ± 0.401
3.043SerThr: 3.043 ± 0.135
2.862SerVal: 2.862 ± 0.189
0.7SerTrp: 0.7 ± 0.056
3.09SerTyr: 3.09 ± 0.09
0.0SerXaa: 0.0 ± 0.0
Thr
2.028ThrAla: 2.028 ± 0.549
3.627ThrCys: 3.627 ± 0.244
3.198ThrAsp: 3.198 ± 0.127
2.96ThrGlu: 2.96 ± 0.112
2.188ThrPhe: 2.188 ± 0.073
2.397ThrGly: 2.397 ± 0.34
1.204ThrHis: 1.204 ± 0.067
4.947ThrIle: 4.947 ± 0.211
5.154ThrLys: 5.154 ± 0.187
3.673ThrLeu: 3.673 ± 0.217
0.938ThrMet: 0.938 ± 0.059
4.813ThrAsn: 4.813 ± 0.209
1.465ThrPro: 1.465 ± 0.074
1.914ThrGln: 1.914 ± 0.089
1.423ThrArg: 1.423 ± 0.085
3.304ThrSer: 3.304 ± 0.25
3.588ThrThr: 3.588 ± 0.471
2.286ThrVal: 2.286 ± 0.222
0.253ThrTrp: 0.253 ± 0.027
2.284ThrTyr: 2.284 ± 0.094
0.0ThrXaa: 0.0 ± 0.0
Val
1.612ValAla: 1.612 ± 0.093
0.84ValCys: 0.84 ± 0.052
2.379ValAsp: 2.379 ± 0.083
2.079ValGlu: 2.079 ± 0.074
1.896ValPhe: 1.896 ± 0.073
1.718ValGly: 1.718 ± 0.195
0.912ValHis: 0.912 ± 0.055
3.715ValIle: 3.715 ± 0.16
3.684ValLys: 3.684 ± 0.125
2.978ValLeu: 2.978 ± 0.112
0.899ValMet: 0.899 ± 0.048
3.575ValAsn: 3.575 ± 0.207
1.144ValPro: 1.144 ± 0.076
1.222ValGln: 1.222 ± 0.077
1.007ValArg: 1.007 ± 0.057
2.493ValSer: 2.493 ± 0.114
1.912ValThr: 1.912 ± 0.125
1.958ValVal: 1.958 ± 0.083
0.258ValTrp: 0.258 ± 0.026
2.392ValTyr: 2.392 ± 0.082
0.0ValXaa: 0.0 ± 0.0
Trp
0.23TrpAla: 0.23 ± 0.022
0.17TrpCys: 0.17 ± 0.026
1.925TrpAsp: 1.925 ± 0.148
0.313TrpGlu: 0.313 ± 0.03
0.421TrpPhe: 0.421 ± 0.036
0.232TrpGly: 0.232 ± 0.024
0.134TrpHis: 0.134 ± 0.019
0.982TrpIle: 0.982 ± 0.054
0.793TrpLys: 0.793 ± 0.044
0.499TrpLeu: 0.499 ± 0.05
0.165TrpMet: 0.165 ± 0.02
1.648TrpAsn: 1.648 ± 0.12
0.013TrpPro: 0.013 ± 0.006
0.207TrpGln: 0.207 ± 0.029
0.163TrpArg: 0.163 ± 0.022
0.411TrpSer: 0.411 ± 0.037
0.651TrpThr: 0.651 ± 0.043
0.207TrpVal: 0.207 ± 0.023
0.075TrpTrp: 0.075 ± 0.015
0.359TrpTyr: 0.359 ± 0.03
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.154TyrAla: 5.154 ± 0.338
1.302TyrCys: 1.302 ± 0.086
4.544TyrAsp: 4.544 ± 0.147
3.286TyrGlu: 3.286 ± 0.112
2.503TyrPhe: 2.503 ± 0.098
2.214TyrGly: 2.214 ± 0.086
1.005TyrHis: 1.005 ± 0.053
4.725TyrIle: 4.725 ± 0.276
4.738TyrLys: 4.738 ± 0.146
4.076TyrLeu: 4.076 ± 0.138
1.222TyrMet: 1.222 ± 0.058
4.947TyrAsn: 4.947 ± 0.161
1.183TyrPro: 1.183 ± 0.054
1.235TyrGln: 1.235 ± 0.135
1.315TyrArg: 1.315 ± 0.061
3.033TyrSer: 3.033 ± 0.122
3.338TyrThr: 3.338 ± 0.116
2.829TyrVal: 2.829 ± 0.132
0.369TyrTrp: 0.369 ± 0.034
2.826TyrTyr: 2.826 ± 0.108
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1186 proteins (387114 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski