Amino acid dipepetide frequency for Verticillium dahliae chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.356AlaAla: 8.356 ± 1.412
1.078AlaCys: 1.078 ± 0.091
5.391AlaAsp: 5.391 ± 0.754
4.852AlaGlu: 4.852 ± 0.691
1.348AlaPhe: 1.348 ± 0.209
4.852AlaGly: 4.852 ± 0.705
1.078AlaHis: 1.078 ± 0.367
5.93AlaIle: 5.93 ± 0.855
5.121AlaLys: 5.121 ± 0.945
7.278AlaLeu: 7.278 ± 0.567
2.426AlaMet: 2.426 ± 0.624
3.504AlaAsn: 3.504 ± 1.074
4.582AlaPro: 4.582 ± 1.375
1.887AlaGln: 1.887 ± 0.32
6.739AlaArg: 6.739 ± 1.605
5.66AlaSer: 5.66 ± 1.228
4.043AlaThr: 4.043 ± 0.24
5.121AlaVal: 5.121 ± 1.339
1.617AlaTrp: 1.617 ± 0.277
1.887AlaTyr: 1.887 ± 0.739
0.0AlaXaa: 0.0 ± 0.0
Cys
0.809CysAla: 0.809 ± 0.438
0.27CysCys: 0.27 ± 0.242
0.539CysAsp: 0.539 ± 0.296
0.539CysGlu: 0.539 ± 0.296
0.27CysPhe: 0.27 ± 0.216
1.348CysGly: 1.348 ± 0.87
0.27CysHis: 0.27 ± 0.216
0.0CysIle: 0.0 ± 0.0
0.809CysLys: 0.809 ± 0.435
1.348CysLeu: 1.348 ± 0.87
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.809CysPro: 0.809 ± 0.435
1.078CysGln: 1.078 ± 0.484
0.809CysArg: 0.809 ± 0.77
0.809CysSer: 0.809 ± 0.476
0.809CysThr: 0.809 ± 0.496
2.426CysVal: 2.426 ± 1.183
0.539CysTrp: 0.539 ± 0.345
0.809CysTyr: 0.809 ± 0.389
0.0CysXaa: 0.0 ± 0.0
Asp
5.391AspAla: 5.391 ± 0.95
0.809AspCys: 0.809 ± 0.452
4.852AspAsp: 4.852 ± 0.741
3.504AspGlu: 3.504 ± 0.402
4.313AspPhe: 4.313 ± 2.045
2.426AspGly: 2.426 ± 0.641
1.617AspHis: 1.617 ± 0.535
2.695AspIle: 2.695 ± 0.764
3.235AspLys: 3.235 ± 0.879
6.469AspLeu: 6.469 ± 0.557
2.426AspMet: 2.426 ± 0.982
2.426AspAsn: 2.426 ± 0.464
1.078AspPro: 1.078 ± 0.348
1.348AspGln: 1.348 ± 0.533
4.313AspArg: 4.313 ± 0.739
5.93AspSer: 5.93 ± 0.884
3.504AspThr: 3.504 ± 1.267
5.391AspVal: 5.391 ± 0.455
1.617AspTrp: 1.617 ± 0.876
4.313AspTyr: 4.313 ± 1.44
0.0AspXaa: 0.0 ± 0.0
Glu
7.008GluAla: 7.008 ± 2.078
0.27GluCys: 0.27 ± 0.216
5.66GluAsp: 5.66 ± 0.275
4.043GluGlu: 4.043 ± 0.43
1.887GluPhe: 1.887 ± 0.352
4.043GluGly: 4.043 ± 0.845
1.078GluHis: 1.078 ± 0.335
2.426GluIle: 2.426 ± 0.344
1.348GluLys: 1.348 ± 0.617
9.164GluLeu: 9.164 ± 1.281
2.965GluMet: 2.965 ± 0.841
0.809GluAsn: 0.809 ± 0.414
2.965GluPro: 2.965 ± 0.956
2.156GluGln: 2.156 ± 0.352
3.774GluArg: 3.774 ± 1.133
4.313GluSer: 4.313 ± 1.026
3.774GluThr: 3.774 ± 0.711
3.504GluVal: 3.504 ± 0.509
0.539GluTrp: 0.539 ± 0.462
1.348GluTyr: 1.348 ± 0.408
0.0GluXaa: 0.0 ± 0.0
Phe
1.887PheAla: 1.887 ± 0.646
1.348PheCys: 1.348 ± 0.875
3.235PheAsp: 3.235 ± 0.606
1.617PheGlu: 1.617 ± 0.675
1.887PhePhe: 1.887 ± 0.693
1.887PheGly: 1.887 ± 0.831
0.539PheHis: 0.539 ± 0.272
0.27PheIle: 0.27 ± 0.231
1.348PheLys: 1.348 ± 0.471
0.539PheLeu: 0.539 ± 0.462
2.156PheMet: 2.156 ± 0.573
2.156PheAsn: 2.156 ± 0.768
0.809PhePro: 0.809 ± 0.183
0.27PheGln: 0.27 ± 0.216
2.426PheArg: 2.426 ± 0.762
2.156PheSer: 2.156 ± 0.548
1.887PheThr: 1.887 ± 0.352
2.156PheVal: 2.156 ± 1.065
0.27PheTrp: 0.27 ± 0.257
0.809PheTyr: 0.809 ± 0.183
0.0PheXaa: 0.0 ± 0.0
Gly
4.582GlyAla: 4.582 ± 0.812
1.078GlyCys: 1.078 ± 0.091
5.66GlyAsp: 5.66 ± 1.031
4.043GlyGlu: 4.043 ± 0.24
2.156GlyPhe: 2.156 ± 0.275
6.199GlyGly: 6.199 ± 1.368
1.617GlyHis: 1.617 ± 0.394
2.965GlyIle: 2.965 ± 0.956
4.313GlyLys: 4.313 ± 0.837
7.547GlyLeu: 7.547 ± 1.649
2.156GlyMet: 2.156 ± 1.14
2.156GlyAsn: 2.156 ± 0.599
2.695GlyPro: 2.695 ± 0.909
2.156GlyGln: 2.156 ± 0.754
7.008GlyArg: 7.008 ± 1.063
5.93GlySer: 5.93 ± 1.091
3.774GlyThr: 3.774 ± 0.959
3.235GlyVal: 3.235 ± 0.52
1.887GlyTrp: 1.887 ± 0.797
1.617GlyTyr: 1.617 ± 0.852
0.0GlyXaa: 0.0 ± 0.0
His
1.887HisAla: 1.887 ± 0.967
0.0HisCys: 0.0 ± 0.0
1.348HisAsp: 1.348 ± 0.776
1.617HisGlu: 1.617 ± 0.475
0.539HisPhe: 0.539 ± 0.462
2.156HisGly: 2.156 ± 0.944
0.27HisHis: 0.27 ± 0.231
1.348HisIle: 1.348 ± 0.209
0.809HisLys: 0.809 ± 0.438
1.617HisLeu: 1.617 ± 0.277
0.27HisMet: 0.27 ± 0.257
0.809HisAsn: 0.809 ± 0.694
0.27HisPro: 0.27 ± 0.257
0.539HisGln: 0.539 ± 0.432
1.078HisArg: 1.078 ± 0.689
2.156HisSer: 2.156 ± 0.709
1.078HisThr: 1.078 ± 0.335
2.156HisVal: 2.156 ± 0.669
0.809HisTrp: 0.809 ± 0.438
1.348HisTyr: 1.348 ± 0.549
0.0HisXaa: 0.0 ± 0.0
Ile
2.965IleAla: 2.965 ± 0.478
1.078IleCys: 1.078 ± 0.462
3.235IleAsp: 3.235 ± 0.554
2.156IleGlu: 2.156 ± 0.795
0.539IlePhe: 0.539 ± 0.257
3.774IleGly: 3.774 ± 0.617
0.539IleHis: 0.539 ± 0.462
3.504IleIle: 3.504 ± 0.296
2.156IleLys: 2.156 ± 0.728
3.504IleLeu: 3.504 ± 0.806
1.078IleMet: 1.078 ± 0.652
2.156IleAsn: 2.156 ± 1.197
2.965IlePro: 2.965 ± 0.436
0.809IleGln: 0.809 ± 0.383
3.235IleArg: 3.235 ± 0.678
2.965IleSer: 2.965 ± 0.961
3.235IleThr: 3.235 ± 0.688
2.965IleVal: 2.965 ± 1.505
0.809IleTrp: 0.809 ± 0.435
1.078IleTyr: 1.078 ± 0.865
0.0IleXaa: 0.0 ± 0.0
Lys
3.774LysAla: 3.774 ± 1.016
0.809LysCys: 0.809 ± 0.77
4.313LysAsp: 4.313 ± 0.581
3.235LysGlu: 3.235 ± 0.489
1.078LysPhe: 1.078 ± 0.091
3.774LysGly: 3.774 ± 0.461
1.078LysHis: 1.078 ± 0.294
2.426LysIle: 2.426 ± 1.317
1.348LysLys: 1.348 ± 0.563
5.66LysLeu: 5.66 ± 1.433
2.695LysMet: 2.695 ± 0.756
0.809LysAsn: 0.809 ± 0.308
1.348LysPro: 1.348 ± 0.471
2.156LysGln: 2.156 ± 0.89
4.043LysArg: 4.043 ± 0.748
2.426LysSer: 2.426 ± 1.118
3.235LysThr: 3.235 ± 1.151
3.235LysVal: 3.235 ± 1.032
0.27LysTrp: 0.27 ± 0.242
2.695LysTyr: 2.695 ± 0.815
0.0LysXaa: 0.0 ± 0.0
Leu
6.469LeuAla: 6.469 ± 0.669
1.078LeuCys: 1.078 ± 0.631
7.278LeuAsp: 7.278 ± 1.78
6.199LeuGlu: 6.199 ± 1.026
3.774LeuPhe: 3.774 ± 1.124
6.469LeuGly: 6.469 ± 1.482
2.965LeuHis: 2.965 ± 0.867
4.043LeuIle: 4.043 ± 0.833
4.313LeuLys: 4.313 ± 0.981
5.66LeuLeu: 5.66 ± 1.385
3.504LeuMet: 3.504 ± 0.562
2.156LeuAsn: 2.156 ± 0.977
2.156LeuPro: 2.156 ± 0.258
1.078LeuGln: 1.078 ± 0.513
6.199LeuArg: 6.199 ± 0.687
5.121LeuSer: 5.121 ± 0.731
7.547LeuThr: 7.547 ± 2.092
8.086LeuVal: 8.086 ± 1.517
2.156LeuTrp: 2.156 ± 1.038
2.695LeuTyr: 2.695 ± 0.66
0.0LeuXaa: 0.0 ± 0.0
Met
4.582MetAla: 4.582 ± 0.637
1.078MetCys: 1.078 ± 0.453
3.774MetAsp: 3.774 ± 1.291
1.078MetGlu: 1.078 ± 0.406
1.348MetPhe: 1.348 ± 0.319
3.235MetGly: 3.235 ± 0.443
1.078MetHis: 1.078 ± 0.338
1.887MetIle: 1.887 ± 0.592
1.078MetLys: 1.078 ± 0.462
0.809MetLeu: 0.809 ± 0.183
0.809MetMet: 0.809 ± 0.249
0.27MetAsn: 0.27 ± 0.231
1.617MetPro: 1.617 ± 0.365
0.809MetGln: 0.809 ± 0.183
3.504MetArg: 3.504 ± 0.473
2.965MetSer: 2.965 ± 0.723
0.539MetThr: 0.539 ± 0.462
2.426MetVal: 2.426 ± 0.464
0.27MetTrp: 0.27 ± 0.257
1.078MetTyr: 1.078 ± 0.544
0.0MetXaa: 0.0 ± 0.0
Asn
2.426AsnAla: 2.426 ± 0.502
0.539AsnCys: 0.539 ± 0.296
2.156AsnAsp: 2.156 ± 0.427
1.078AsnGlu: 1.078 ± 0.652
0.539AsnPhe: 0.539 ± 0.227
2.695AsnGly: 2.695 ± 0.679
1.078AsnHis: 1.078 ± 0.544
1.348AsnIle: 1.348 ± 0.549
1.887AsnLys: 1.887 ± 0.595
3.235AsnLeu: 3.235 ± 0.871
1.348AsnMet: 1.348 ± 0.687
1.078AsnAsn: 1.078 ± 0.338
0.539AsnPro: 0.539 ± 0.272
2.156AsnGln: 2.156 ± 0.731
1.348AsnArg: 1.348 ± 0.548
1.617AsnSer: 1.617 ± 0.416
1.887AsnThr: 1.887 ± 0.646
1.617AsnVal: 1.617 ± 0.535
0.809AsnTrp: 0.809 ± 0.183
1.348AsnTyr: 1.348 ± 0.464
0.0AsnXaa: 0.0 ± 0.0
Pro
4.043ProAla: 4.043 ± 0.925
0.539ProCys: 0.539 ± 0.257
3.504ProAsp: 3.504 ± 1.056
2.426ProGlu: 2.426 ± 0.617
0.539ProPhe: 0.539 ± 0.244
2.156ProGly: 2.156 ± 0.696
1.348ProHis: 1.348 ± 0.549
1.348ProIle: 1.348 ± 0.319
2.156ProLys: 2.156 ± 0.659
1.617ProLeu: 1.617 ± 0.434
0.539ProMet: 0.539 ± 0.244
1.617ProAsn: 1.617 ± 0.95
2.156ProPro: 2.156 ± 0.866
2.156ProGln: 2.156 ± 0.574
3.504ProArg: 3.504 ± 1.078
4.852ProSer: 4.852 ± 1.196
1.078ProThr: 1.078 ± 0.379
3.235ProVal: 3.235 ± 0.652
1.078ProTrp: 1.078 ± 0.091
0.809ProTyr: 0.809 ± 0.308
0.0ProXaa: 0.0 ± 0.0
Gln
1.617GlnAla: 1.617 ± 0.557
0.809GlnCys: 0.809 ± 0.558
1.078GlnAsp: 1.078 ± 0.335
1.887GlnGlu: 1.887 ± 0.35
0.809GlnPhe: 0.809 ± 0.459
3.504GlnGly: 3.504 ± 1.178
0.539GlnHis: 0.539 ± 0.257
1.078GlnIle: 1.078 ± 0.406
0.809GlnLys: 0.809 ± 0.408
3.235GlnLeu: 3.235 ± 0.811
1.078GlnMet: 1.078 ± 0.294
0.539GlnAsn: 0.539 ± 0.257
1.887GlnPro: 1.887 ± 0.629
1.348GlnGln: 1.348 ± 0.482
2.426GlnArg: 2.426 ± 0.476
2.426GlnSer: 2.426 ± 0.973
2.156GlnThr: 2.156 ± 0.709
1.887GlnVal: 1.887 ± 0.355
0.27GlnTrp: 0.27 ± 0.257
1.078GlnTyr: 1.078 ± 0.641
0.0GlnXaa: 0.0 ± 0.0
Arg
4.582ArgAla: 4.582 ± 1.211
0.539ArgCys: 0.539 ± 0.244
2.695ArgAsp: 2.695 ± 0.355
8.895ArgGlu: 8.895 ± 1.487
1.348ArgPhe: 1.348 ± 0.549
5.391ArgGly: 5.391 ± 0.983
2.426ArgHis: 2.426 ± 1.139
1.887ArgIle: 1.887 ± 0.825
4.043ArgLys: 4.043 ± 0.614
9.164ArgLeu: 9.164 ± 1.318
0.809ArgMet: 0.809 ± 0.258
2.156ArgAsn: 2.156 ± 0.521
4.043ArgPro: 4.043 ± 1.185
2.695ArgGln: 2.695 ± 1.041
7.008ArgArg: 7.008 ± 1.963
3.504ArgSer: 3.504 ± 0.395
3.774ArgThr: 3.774 ± 1.342
5.66ArgVal: 5.66 ± 0.857
0.539ArgTrp: 0.539 ± 0.257
3.504ArgTyr: 3.504 ± 1.178
0.0ArgXaa: 0.0 ± 0.0
Ser
5.93SerAla: 5.93 ± 1.131
0.809SerCys: 0.809 ± 0.408
3.504SerAsp: 3.504 ± 1.204
3.504SerGlu: 3.504 ± 0.799
2.965SerPhe: 2.965 ± 0.516
5.66SerGly: 5.66 ± 0.961
1.078SerHis: 1.078 ± 0.498
2.156SerIle: 2.156 ± 0.696
4.582SerLys: 4.582 ± 0.882
6.739SerLeu: 6.739 ± 0.673
4.043SerMet: 4.043 ± 0.698
1.617SerAsn: 1.617 ± 0.778
3.235SerPro: 3.235 ± 0.87
2.965SerGln: 2.965 ± 0.181
5.391SerArg: 5.391 ± 0.985
7.278SerSer: 7.278 ± 0.467
2.695SerThr: 2.695 ± 0.951
5.391SerVal: 5.391 ± 2.042
1.078SerTrp: 1.078 ± 0.379
1.617SerTyr: 1.617 ± 0.394
0.0SerXaa: 0.0 ± 0.0
Thr
5.93ThrAla: 5.93 ± 1.067
0.809ThrCys: 0.809 ± 0.459
1.078ThrAsp: 1.078 ± 0.338
3.774ThrGlu: 3.774 ± 0.599
2.156ThrPhe: 2.156 ± 0.648
2.965ThrGly: 2.965 ± 1.063
1.348ThrHis: 1.348 ± 0.408
1.617ThrIle: 1.617 ± 0.552
4.313ThrLys: 4.313 ± 0.785
4.313ThrLeu: 4.313 ± 0.857
2.156ThrMet: 2.156 ± 0.944
1.078ThrAsn: 1.078 ± 0.488
2.426ThrPro: 2.426 ± 1.022
1.348ThrGln: 1.348 ± 0.719
5.121ThrArg: 5.121 ± 0.413
4.582ThrSer: 4.582 ± 1.017
4.582ThrThr: 4.582 ± 0.355
3.774ThrVal: 3.774 ± 0.617
1.348ThrTrp: 1.348 ± 0.593
1.887ThrTyr: 1.887 ± 0.32
0.0ThrXaa: 0.0 ± 0.0
Val
6.739ValAla: 6.739 ± 1.899
0.809ValCys: 0.809 ± 0.183
4.852ValAsp: 4.852 ± 0.862
4.852ValGlu: 4.852 ± 0.564
1.078ValPhe: 1.078 ± 0.652
7.008ValGly: 7.008 ± 0.917
0.809ValHis: 0.809 ± 0.414
4.582ValIle: 4.582 ± 0.812
4.043ValLys: 4.043 ± 0.808
7.278ValLeu: 7.278 ± 1.306
2.156ValMet: 2.156 ± 0.779
2.965ValAsn: 2.965 ± 1.196
4.582ValPro: 4.582 ± 0.568
2.156ValGln: 2.156 ± 0.568
3.235ValArg: 3.235 ± 0.606
4.582ValSer: 4.582 ± 0.775
3.235ValThr: 3.235 ± 0.768
4.852ValVal: 4.852 ± 1.318
1.617ValTrp: 1.617 ± 0.29
1.887ValTyr: 1.887 ± 0.355
0.0ValXaa: 0.0 ± 0.0
Trp
1.078TrpAla: 1.078 ± 0.419
0.539TrpCys: 0.539 ± 0.272
0.809TrpAsp: 0.809 ± 0.558
2.156TrpGlu: 2.156 ± 0.427
0.539TrpPhe: 0.539 ± 0.462
1.078TrpGly: 1.078 ± 0.714
0.809TrpHis: 0.809 ± 0.537
1.348TrpIle: 1.348 ± 0.634
0.809TrpLys: 0.809 ± 0.694
1.617TrpLeu: 1.617 ± 0.344
0.27TrpMet: 0.27 ± 0.231
0.27TrpAsn: 0.27 ± 0.231
0.0TrpPro: 0.0 ± 0.0
0.27TrpGln: 0.27 ± 0.231
1.078TrpArg: 1.078 ± 0.367
0.809TrpSer: 0.809 ± 0.308
1.078TrpThr: 1.078 ± 0.513
2.695TrpVal: 2.695 ± 0.918
0.27TrpTrp: 0.27 ± 0.216
0.27TrpTyr: 0.27 ± 0.257
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.965TyrAla: 2.965 ± 1.105
0.0TyrCys: 0.0 ± 0.0
2.695TyrAsp: 2.695 ± 1.403
1.617TyrGlu: 1.617 ± 0.56
0.539TyrPhe: 0.539 ± 0.257
2.156TyrGly: 2.156 ± 0.728
0.539TyrHis: 0.539 ± 0.227
1.887TyrIle: 1.887 ± 0.752
1.887TyrLys: 1.887 ± 0.639
2.156TyrLeu: 2.156 ± 0.347
1.078TyrMet: 1.078 ± 0.091
2.156TyrAsn: 2.156 ± 0.635
0.539TyrPro: 0.539 ± 0.244
1.078TyrGln: 1.078 ± 0.338
2.426TyrArg: 2.426 ± 0.882
2.156TyrSer: 2.156 ± 0.269
2.695TyrThr: 2.695 ± 1.113
3.504TyrVal: 3.504 ± 0.75
0.0TyrTrp: 0.0 ± 0.0
0.809TyrTyr: 0.809 ± 0.435
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3711 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski