Amino acid dipepetide frequency for Campylobacter volucris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.348AlaAla: 3.348 ± 0.105
1.097AlaCys: 1.097 ± 0.055
2.475AlaAsp: 2.475 ± 0.073
2.107AlaGlu: 2.107 ± 0.076
3.614AlaPhe: 3.614 ± 0.111
3.427AlaGly: 3.427 ± 0.096
1.154AlaHis: 1.154 ± 0.048
5.995AlaIle: 5.995 ± 0.123
7.437AlaLys: 7.437 ± 0.14
8.544AlaLeu: 8.544 ± 0.168
1.841AlaMet: 1.841 ± 0.075
4.297AlaAsn: 4.297 ± 0.093
1.605AlaPro: 1.605 ± 0.055
2.356AlaGln: 2.356 ± 0.071
2.351AlaArg: 2.351 ± 0.077
4.407AlaSer: 4.407 ± 0.1
2.581AlaThr: 2.581 ± 0.079
3.123AlaVal: 3.123 ± 0.088
0.449AlaTrp: 0.449 ± 0.035
2.94AlaTyr: 2.94 ± 0.077
0.0AlaXaa: 0.0 ± 0.0
Cys
0.986CysAla: 0.986 ± 0.045
0.14CysCys: 0.14 ± 0.02
0.844CysAsp: 0.844 ± 0.041
1.114CysGlu: 1.114 ± 0.052
0.755CysPhe: 0.755 ± 0.041
0.933CysGly: 0.933 ± 0.045
0.261CysHis: 0.261 ± 0.032
1.21CysIle: 1.21 ± 0.054
1.11CysLys: 1.11 ± 0.054
1.05CysLeu: 1.05 ± 0.047
0.283CysMet: 0.283 ± 0.023
0.512CysAsn: 0.512 ± 0.034
0.357CysPro: 0.357 ± 0.03
0.287CysGln: 0.287 ± 0.024
0.247CysArg: 0.247 ± 0.021
0.806CysSer: 0.806 ± 0.044
0.387CysThr: 0.387 ± 0.028
0.899CysVal: 0.899 ± 0.046
0.049CysTrp: 0.049 ± 0.011
0.372CysTyr: 0.372 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
2.978AspAla: 2.978 ± 0.093
0.608AspCys: 0.608 ± 0.032
3.049AspAsp: 3.049 ± 0.082
5.493AspGlu: 5.493 ± 0.1
4.318AspPhe: 4.318 ± 0.09
2.959AspGly: 2.959 ± 0.091
0.661AspHis: 0.661 ± 0.037
5.257AspIle: 5.257 ± 0.099
5.24AspLys: 5.24 ± 0.109
5.678AspLeu: 5.678 ± 0.114
1.176AspMet: 1.176 ± 0.049
2.66AspAsn: 2.66 ± 0.08
1.318AspPro: 1.318 ± 0.054
1.284AspGln: 1.284 ± 0.048
1.393AspArg: 1.393 ± 0.059
2.619AspSer: 2.619 ± 0.084
2.073AspThr: 2.073 ± 0.062
2.925AspVal: 2.925 ± 0.09
0.253AspTrp: 0.253 ± 0.025
2.413AspTyr: 2.413 ± 0.066
0.0AspXaa: 0.0 ± 0.0
Glu
3.92GluAla: 3.92 ± 0.115
0.861GluCys: 0.861 ± 0.045
3.446GluAsp: 3.446 ± 0.092
5.128GluGlu: 5.128 ± 0.145
4.613GluPhe: 4.613 ± 0.11
2.696GluGly: 2.696 ± 0.094
1.184GluHis: 1.184 ± 0.056
6.724GluIle: 6.724 ± 0.136
7.87GluLys: 7.87 ± 0.146
7.428GluLeu: 7.428 ± 0.161
1.305GluMet: 1.305 ± 0.056
6.191GluAsn: 6.191 ± 0.109
1.205GluPro: 1.205 ± 0.051
2.704GluGln: 2.704 ± 0.08
1.907GluArg: 1.907 ± 0.063
3.183GluSer: 3.183 ± 0.079
1.703GluThr: 1.703 ± 0.065
3.419GluVal: 3.419 ± 0.082
0.421GluTrp: 0.421 ± 0.033
2.662GluTyr: 2.662 ± 0.066
0.0GluXaa: 0.0 ± 0.0
Phe
3.937PheAla: 3.937 ± 0.094
1.003PheCys: 1.003 ± 0.049
3.865PheAsp: 3.865 ± 0.092
3.954PheGlu: 3.954 ± 0.09
3.631PhePhe: 3.631 ± 0.106
3.355PheGly: 3.355 ± 0.085
0.799PheHis: 0.799 ± 0.039
5.549PheIle: 5.549 ± 0.122
5.425PheLys: 5.425 ± 0.124
6.841PheLeu: 6.841 ± 0.158
1.301PheMet: 1.301 ± 0.051
3.461PheAsn: 3.461 ± 0.091
1.048PhePro: 1.048 ± 0.054
1.278PheGln: 1.278 ± 0.055
1.261PheArg: 1.261 ± 0.052
4.324PheSer: 4.324 ± 0.105
2.366PheThr: 2.366 ± 0.078
3.229PheVal: 3.229 ± 0.103
0.495PheTrp: 0.495 ± 0.033
2.823PheTyr: 2.823 ± 0.065
0.0PheXaa: 0.0 ± 0.0
Gly
4.039GlyAla: 4.039 ± 0.11
0.638GlyCys: 0.638 ± 0.037
2.536GlyAsp: 2.536 ± 0.082
3.236GlyGlu: 3.236 ± 0.095
3.478GlyPhe: 3.478 ± 0.084
3.608GlyGly: 3.608 ± 0.12
0.884GlyHis: 0.884 ± 0.047
5.017GlyIle: 5.017 ± 0.114
4.541GlyLys: 4.541 ± 0.111
5.107GlyLeu: 5.107 ± 0.111
1.286GlyMet: 1.286 ± 0.055
2.343GlyAsn: 2.343 ± 0.089
0.844GlyPro: 0.844 ± 0.045
1.329GlyGln: 1.329 ± 0.06
1.556GlyArg: 1.556 ± 0.059
3.259GlySer: 3.259 ± 0.099
2.083GlyThr: 2.083 ± 0.085
4.314GlyVal: 4.314 ± 0.118
0.366GlyTrp: 0.366 ± 0.028
2.281GlyTyr: 2.281 ± 0.078
0.0GlyXaa: 0.0 ± 0.0
His
0.895HisAla: 0.895 ± 0.039
0.227HisCys: 0.227 ± 0.022
0.691HisAsp: 0.691 ± 0.043
1.014HisGlu: 1.014 ± 0.048
1.201HisPhe: 1.201 ± 0.052
0.944HisGly: 0.944 ± 0.051
0.395HisHis: 0.395 ± 0.033
1.463HisIle: 1.463 ± 0.054
1.45HisLys: 1.45 ± 0.057
1.841HisLeu: 1.841 ± 0.072
0.323HisMet: 0.323 ± 0.027
0.848HisAsn: 0.848 ± 0.043
0.708HisPro: 0.708 ± 0.04
0.64HisGln: 0.64 ± 0.037
0.502HisArg: 0.502 ± 0.035
1.133HisSer: 1.133 ± 0.051
0.863HisThr: 0.863 ± 0.05
0.57HisVal: 0.57 ± 0.033
0.091HisTrp: 0.091 ± 0.016
0.64HisTyr: 0.64 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
6.773IleAla: 6.773 ± 0.129
1.375IleCys: 1.375 ± 0.059
5.245IleAsp: 5.245 ± 0.088
5.902IleGlu: 5.902 ± 0.119
5.474IlePhe: 5.474 ± 0.132
4.807IleGly: 4.807 ± 0.139
1.38IleHis: 1.38 ± 0.056
7.957IleIle: 7.957 ± 0.159
8.85IleLys: 8.85 ± 0.145
10.215IleLeu: 10.215 ± 0.155
1.735IleMet: 1.735 ± 0.068
5.957IleAsn: 5.957 ± 0.11
2.581IlePro: 2.581 ± 0.078
2.819IleGln: 2.819 ± 0.089
2.185IleArg: 2.185 ± 0.075
6.34IleSer: 6.34 ± 0.116
3.799IleThr: 3.799 ± 0.09
4.824IleVal: 4.824 ± 0.106
0.544IleTrp: 0.544 ± 0.035
3.655IleTyr: 3.655 ± 0.094
0.0IleXaa: 0.0 ± 0.0
Lys
6.34LysAla: 6.34 ± 0.126
0.825LysCys: 0.825 ± 0.043
6.741LysAsp: 6.741 ± 0.132
9.312LysGlu: 9.312 ± 0.163
4.573LysPhe: 4.573 ± 0.094
3.882LysGly: 3.882 ± 0.102
1.446LysHis: 1.446 ± 0.058
10.362LysIle: 10.362 ± 0.146
8.78LysLys: 8.78 ± 0.178
8.166LysLeu: 8.166 ± 0.131
2.239LysMet: 2.239 ± 0.068
8.748LysAsn: 8.748 ± 0.164
2.215LysPro: 2.215 ± 0.068
3.397LysGln: 3.397 ± 0.094
2.592LysArg: 2.592 ± 0.075
5.181LysSer: 5.181 ± 0.098
4.728LysThr: 4.728 ± 0.107
4.324LysVal: 4.324 ± 0.116
0.472LysTrp: 0.472 ± 0.036
3.344LysTyr: 3.344 ± 0.086
0.0LysXaa: 0.0 ± 0.0
Leu
7.611LeuAla: 7.611 ± 0.137
1.473LeuCys: 1.473 ± 0.058
6.11LeuAsp: 6.11 ± 0.114
7.647LeuGlu: 7.647 ± 0.154
5.434LeuPhe: 5.434 ± 0.127
5.861LeuGly: 5.861 ± 0.127
1.55LeuHis: 1.55 ± 0.06
8.223LeuIle: 8.223 ± 0.152
11.655LeuLys: 11.655 ± 0.179
9.431LeuLeu: 9.431 ± 0.152
2.285LeuMet: 2.285 ± 0.069
7.566LeuAsn: 7.566 ± 0.139
2.961LeuPro: 2.961 ± 0.094
3.706LeuGln: 3.706 ± 0.103
2.993LeuArg: 2.993 ± 0.078
7.728LeuSer: 7.728 ± 0.146
3.676LeuThr: 3.676 ± 0.089
4.894LeuVal: 4.894 ± 0.11
0.653LeuTrp: 0.653 ± 0.042
3.501LeuTyr: 3.501 ± 0.088
0.0LeuXaa: 0.0 ± 0.0
Met
1.467MetAla: 1.467 ± 0.051
0.247MetCys: 0.247 ± 0.022
1.169MetAsp: 1.169 ± 0.05
1.065MetGlu: 1.065 ± 0.051
1.046MetPhe: 1.046 ± 0.042
1.356MetGly: 1.356 ± 0.058
0.415MetHis: 0.415 ± 0.027
2.13MetIle: 2.13 ± 0.077
2.098MetLys: 2.098 ± 0.065
2.445MetLeu: 2.445 ± 0.078
0.555MetMet: 0.555 ± 0.038
1.084MetAsn: 1.084 ± 0.042
0.918MetPro: 0.918 ± 0.042
1.314MetGln: 1.314 ± 0.053
0.691MetArg: 0.691 ± 0.04
1.582MetSer: 1.582 ± 0.067
0.651MetThr: 0.651 ± 0.038
1.171MetVal: 1.171 ± 0.051
0.111MetTrp: 0.111 ± 0.015
0.563MetTyr: 0.563 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
4.418AsnAla: 4.418 ± 0.106
0.559AsnCys: 0.559 ± 0.034
3.593AsnAsp: 3.593 ± 0.084
5.009AsnGlu: 5.009 ± 0.101
4.233AsnPhe: 4.233 ± 0.107
3.151AsnGly: 3.151 ± 0.111
1.188AsnHis: 1.188 ± 0.05
6.586AsnIle: 6.586 ± 0.141
4.99AsnLys: 4.99 ± 0.112
8.17AsnLeu: 8.17 ± 0.163
1.146AsnMet: 1.146 ± 0.052
3.608AsnAsn: 3.608 ± 0.118
2.254AsnPro: 2.254 ± 0.063
2.29AsnGln: 2.29 ± 0.074
1.335AsnArg: 1.335 ± 0.05
3.954AsnSer: 3.954 ± 0.088
3.327AsnThr: 3.327 ± 0.086
2.845AsnVal: 2.845 ± 0.079
0.296AsnTrp: 0.296 ± 0.026
2.528AsnTyr: 2.528 ± 0.079
0.0AsnXaa: 0.0 ± 0.0
Pro
1.324ProAla: 1.324 ± 0.059
0.353ProCys: 0.353 ± 0.029
1.178ProAsp: 1.178 ± 0.053
1.278ProGlu: 1.278 ± 0.055
1.599ProPhe: 1.599 ± 0.065
1.052ProGly: 1.052 ± 0.049
0.525ProHis: 0.525 ± 0.035
2.122ProIle: 2.122 ± 0.073
2.645ProLys: 2.645 ± 0.083
2.944ProLeu: 2.944 ± 0.072
0.566ProMet: 0.566 ± 0.037
1.818ProAsn: 1.818 ± 0.068
0.64ProPro: 0.64 ± 0.038
1.088ProGln: 1.088 ± 0.042
0.744ProArg: 0.744 ± 0.041
1.932ProSer: 1.932 ± 0.066
1.205ProThr: 1.205 ± 0.047
1.399ProVal: 1.399 ± 0.067
0.249ProTrp: 0.249 ± 0.023
1.171ProTyr: 1.171 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
2.524GlnAla: 2.524 ± 0.067
0.276GlnCys: 0.276 ± 0.024
1.932GlnAsp: 1.932 ± 0.063
2.834GlnGlu: 2.834 ± 0.086
1.233GlnPhe: 1.233 ± 0.054
1.635GlnGly: 1.635 ± 0.068
0.351GlnHis: 0.351 ± 0.03
3.665GlnIle: 3.665 ± 0.097
4.02GlnLys: 4.02 ± 0.114
2.117GlnLeu: 2.117 ± 0.07
0.81GlnMet: 0.81 ± 0.041
3.518GlnAsn: 3.518 ± 0.109
0.47GlnPro: 0.47 ± 0.034
0.676GlnGln: 0.676 ± 0.041
1.108GlnArg: 1.108 ± 0.047
2.062GlnSer: 2.062 ± 0.061
1.741GlnThr: 1.741 ± 0.069
1.465GlnVal: 1.465 ± 0.053
0.183GlnTrp: 0.183 ± 0.019
0.895GlnTyr: 0.895 ± 0.048
0.0GlnXaa: 0.0 ± 0.0
Arg
1.979ArgAla: 1.979 ± 0.057
0.3ArgCys: 0.3 ± 0.024
1.286ArgAsp: 1.286 ± 0.052
1.837ArgGlu: 1.837 ± 0.068
1.735ArgPhe: 1.735 ± 0.064
1.395ArgGly: 1.395 ± 0.056
0.455ArgHis: 0.455 ± 0.036
2.56ArgIle: 2.56 ± 0.078
2.449ArgLys: 2.449 ± 0.073
2.985ArgLeu: 2.985 ± 0.082
0.725ArgMet: 0.725 ± 0.041
1.405ArgAsn: 1.405 ± 0.05
0.708ArgPro: 0.708 ± 0.036
0.899ArgGln: 0.899 ± 0.04
0.989ArgArg: 0.989 ± 0.043
1.495ArgSer: 1.495 ± 0.053
1.042ArgThr: 1.042 ± 0.051
1.724ArgVal: 1.724 ± 0.055
0.179ArgTrp: 0.179 ± 0.018
1.242ArgTyr: 1.242 ± 0.047
0.0ArgXaa: 0.0 ± 0.0
Ser
3.916SerAla: 3.916 ± 0.095
0.767SerCys: 0.767 ± 0.039
3.029SerAsp: 3.029 ± 0.093
3.242SerGlu: 3.242 ± 0.088
4.328SerPhe: 4.328 ± 0.115
3.816SerGly: 3.816 ± 0.099
1.069SerHis: 1.069 ± 0.052
5.723SerIle: 5.723 ± 0.115
6.301SerLys: 6.301 ± 0.107
6.958SerLeu: 6.958 ± 0.12
1.478SerMet: 1.478 ± 0.053
3.703SerAsn: 3.703 ± 0.093
1.446SerPro: 1.446 ± 0.053
2.117SerGln: 2.117 ± 0.066
1.637SerArg: 1.637 ± 0.058
4.369SerSer: 4.369 ± 0.102
2.623SerThr: 2.623 ± 0.075
3.508SerVal: 3.508 ± 0.088
0.436SerTrp: 0.436 ± 0.036
2.798SerTyr: 2.798 ± 0.086
0.0SerXaa: 0.0 ± 0.0
Thr
2.202ThrAla: 2.202 ± 0.073
0.504ThrCys: 0.504 ± 0.037
1.492ThrAsp: 1.492 ± 0.064
1.384ThrGlu: 1.384 ± 0.054
2.285ThrPhe: 2.285 ± 0.075
2.171ThrGly: 2.171 ± 0.088
1.033ThrHis: 1.033 ± 0.048
3.672ThrIle: 3.672 ± 0.092
3.912ThrLys: 3.912 ± 0.093
4.922ThrLeu: 4.922 ± 0.101
0.899ThrMet: 0.899 ± 0.04
2.579ThrAsn: 2.579 ± 0.073
1.867ThrPro: 1.867 ± 0.067
2.234ThrGln: 2.234 ± 0.081
1.195ThrArg: 1.195 ± 0.06
2.906ThrSer: 2.906 ± 0.074
2.049ThrThr: 2.049 ± 0.071
1.112ThrVal: 1.112 ± 0.051
0.33ThrTrp: 0.33 ± 0.031
1.718ThrTyr: 1.718 ± 0.06
0.0ThrXaa: 0.0 ± 0.0
Val
3.544ValAla: 3.544 ± 0.112
0.81ValCys: 0.81 ± 0.042
3.002ValAsp: 3.002 ± 0.083
3.178ValGlu: 3.178 ± 0.098
3.338ValPhe: 3.338 ± 0.093
3.144ValGly: 3.144 ± 0.091
0.731ValHis: 0.731 ± 0.051
4.43ValIle: 4.43 ± 0.105
4.59ValLys: 4.59 ± 0.118
5.721ValLeu: 5.721 ± 0.117
1.165ValMet: 1.165 ± 0.046
2.696ValAsn: 2.696 ± 0.084
1.354ValPro: 1.354 ± 0.057
1.393ValGln: 1.393 ± 0.059
1.497ValArg: 1.497 ± 0.065
3.512ValSer: 3.512 ± 0.092
1.427ValThr: 1.427 ± 0.058
3.805ValVal: 3.805 ± 0.093
0.308ValTrp: 0.308 ± 0.025
1.956ValTyr: 1.956 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
0.417TrpAla: 0.417 ± 0.034
0.111TrpCys: 0.111 ± 0.014
0.327TrpAsp: 0.327 ± 0.03
0.334TrpGlu: 0.334 ± 0.029
0.34TrpPhe: 0.34 ± 0.03
0.461TrpGly: 0.461 ± 0.035
0.159TrpHis: 0.159 ± 0.019
0.583TrpIle: 0.583 ± 0.035
0.361TrpLys: 0.361 ± 0.027
0.693TrpLeu: 0.693 ± 0.041
0.208TrpMet: 0.208 ± 0.023
0.268TrpAsn: 0.268 ± 0.024
0.096TrpPro: 0.096 ± 0.014
0.338TrpGln: 0.338 ± 0.029
0.162TrpArg: 0.162 ± 0.017
0.327TrpSer: 0.327 ± 0.028
0.244TrpThr: 0.244 ± 0.024
0.374TrpVal: 0.374 ± 0.027
0.091TrpTrp: 0.091 ± 0.014
0.276TrpTyr: 0.276 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.528TyrAla: 2.528 ± 0.083
0.427TyrCys: 0.427 ± 0.032
2.345TyrAsp: 2.345 ± 0.076
3.504TyrGlu: 3.504 ± 0.097
2.719TyrPhe: 2.719 ± 0.086
2.092TyrGly: 2.092 ± 0.087
0.797TyrHis: 0.797 ± 0.041
3.189TyrIle: 3.189 ± 0.093
3.944TyrLys: 3.944 ± 0.087
3.701TyrLeu: 3.701 ± 0.1
0.75TyrMet: 0.75 ± 0.04
2.215TyrAsn: 2.215 ± 0.078
1.237TyrPro: 1.237 ± 0.053
1.367TyrGln: 1.367 ± 0.058
1.044TyrArg: 1.044 ± 0.046
2.147TyrSer: 2.147 ± 0.074
1.896TyrThr: 1.896 ± 0.066
1.677TyrVal: 1.677 ± 0.07
0.198TyrTrp: 0.198 ± 0.022
1.573TyrTyr: 1.573 ± 0.071
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1515 proteins (470377 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski