Amino acid dipepetide frequency for Hubei polero-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.364AlaAla: 6.364 ± 1.308
0.909AlaCys: 0.909 ± 1.083
1.818AlaAsp: 1.818 ± 0.775
4.545AlaGlu: 4.545 ± 1.551
1.818AlaPhe: 1.818 ± 0.986
7.273AlaGly: 7.273 ± 0.848
0.909AlaHis: 0.909 ± 0.542
3.636AlaIle: 3.636 ± 1.103
2.727AlaLys: 2.727 ± 1.625
10.0AlaLeu: 10.0 ± 2.985
2.727AlaMet: 2.727 ± 0.784
1.818AlaAsn: 1.818 ± 0.775
6.364AlaPro: 6.364 ± 3.792
3.636AlaGln: 3.636 ± 1.103
4.545AlaArg: 4.545 ± 2.363
5.455AlaSer: 5.455 ± 2.958
5.455AlaThr: 5.455 ± 2.168
4.545AlaVal: 4.545 ± 0.321
0.909AlaTrp: 0.909 ± 0.542
2.727AlaTyr: 2.727 ± 2.394
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.818CysPhe: 1.818 ± 0.775
0.909CysGly: 0.909 ± 1.083
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.818CysLys: 1.818 ± 0.986
3.636CysLeu: 3.636 ± 1.55
0.0CysMet: 0.0 ± 0.0
1.818CysAsn: 1.818 ± 0.986
0.909CysPro: 0.909 ± 1.165
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.727CysSer: 2.727 ± 1.804
0.0CysThr: 0.0 ± 0.0
1.818CysVal: 1.818 ± 1.084
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.727AspAla: 2.727 ± 0.919
1.818AspCys: 1.818 ± 1.447
1.818AspAsp: 1.818 ± 2.166
1.818AspGlu: 1.818 ± 1.084
0.909AspPhe: 0.909 ± 1.083
5.455AspGly: 5.455 ± 1.569
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.909AspLys: 0.909 ± 0.542
4.545AspLeu: 4.545 ± 1.238
0.909AspMet: 0.909 ± 1.083
0.909AspAsn: 0.909 ± 1.165
1.818AspPro: 1.818 ± 1.447
2.727AspGln: 2.727 ± 0.919
0.909AspArg: 0.909 ± 0.542
1.818AspSer: 1.818 ± 0.986
0.909AspThr: 0.909 ± 0.542
0.909AspVal: 0.909 ± 0.542
1.818AspTrp: 1.818 ± 2.166
0.909AspTyr: 0.909 ± 0.542
0.0AspXaa: 0.0 ± 0.0
Glu
2.727GluAla: 2.727 ± 0.919
0.0GluCys: 0.0 ± 0.0
2.727GluAsp: 2.727 ± 1.084
4.545GluGlu: 4.545 ± 1.462
2.727GluPhe: 2.727 ± 0.919
1.818GluGly: 1.818 ± 1.084
2.727GluHis: 2.727 ± 1.625
2.727GluIle: 2.727 ± 0.784
2.727GluLys: 2.727 ± 1.625
2.727GluLeu: 2.727 ± 0.919
2.727GluMet: 2.727 ± 0.88
3.636GluAsn: 3.636 ± 1.103
0.909GluPro: 0.909 ± 0.542
0.0GluGln: 0.0 ± 0.0
1.818GluArg: 1.818 ± 0.775
2.727GluSer: 2.727 ± 0.784
4.545GluThr: 4.545 ± 0.321
5.455GluVal: 5.455 ± 3.608
2.727GluTrp: 2.727 ± 0.919
2.727GluTyr: 2.727 ± 0.919
0.0GluXaa: 0.0 ± 0.0
Phe
2.727PheAla: 2.727 ± 0.919
0.909PheCys: 0.909 ± 1.083
0.909PheAsp: 0.909 ± 1.083
1.818PheGlu: 1.818 ± 0.986
0.0PhePhe: 0.0 ± 0.0
2.727PheGly: 2.727 ± 0.919
0.909PheHis: 0.909 ± 0.542
2.727PheIle: 2.727 ± 1.084
3.636PheLys: 3.636 ± 1.103
3.636PheLeu: 3.636 ± 2.167
0.0PheMet: 0.0 ± 0.0
0.909PheAsn: 0.909 ± 0.542
0.909PhePro: 0.909 ± 0.542
1.818PheGln: 1.818 ± 0.775
2.727PheArg: 2.727 ± 2.09
7.273PheSer: 7.273 ± 2.803
4.545PheThr: 4.545 ± 2.0
2.727PheVal: 2.727 ± 2.275
0.0PheTrp: 0.0 ± 0.0
0.909PheTyr: 0.909 ± 0.542
0.0PheXaa: 0.0 ± 0.0
Gly
3.636GlyAla: 3.636 ± 0.424
1.818GlyCys: 1.818 ± 1.084
2.727GlyAsp: 2.727 ± 0.919
2.727GlyGlu: 2.727 ± 1.625
5.455GlyPhe: 5.455 ± 2.325
1.818GlyGly: 1.818 ± 0.986
0.0GlyHis: 0.0 ± 0.0
2.727GlyIle: 2.727 ± 1.084
8.182GlyLys: 8.182 ± 2.38
3.636GlyLeu: 3.636 ± 0.424
0.0GlyMet: 0.0 ± 0.0
3.636GlyAsn: 3.636 ± 1.972
4.545GlyPro: 4.545 ± 1.828
3.636GlyGln: 3.636 ± 1.55
4.545GlyArg: 4.545 ± 3.053
11.818GlySer: 11.818 ± 0.896
5.455GlyThr: 5.455 ± 1.305
4.545GlyVal: 4.545 ± 0.321
0.909GlyTrp: 0.909 ± 1.083
1.818GlyTyr: 1.818 ± 0.775
0.0GlyXaa: 0.0 ± 0.0
His
1.818HisAla: 1.818 ± 1.084
1.818HisCys: 1.818 ± 1.447
2.727HisAsp: 2.727 ± 0.919
0.909HisGlu: 0.909 ± 1.165
1.818HisPhe: 1.818 ± 1.084
0.909HisGly: 0.909 ± 0.542
0.0HisHis: 0.0 ± 0.0
0.909HisIle: 0.909 ± 0.542
0.0HisLys: 0.0 ± 0.0
0.909HisLeu: 0.909 ± 0.542
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.727HisSer: 2.727 ± 1.625
0.909HisThr: 0.909 ± 1.083
0.909HisVal: 0.909 ± 0.542
0.909HisTrp: 0.909 ± 0.542
0.909HisTyr: 0.909 ± 1.165
0.0HisXaa: 0.0 ± 0.0
Ile
3.636IleAla: 3.636 ± 1.75
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
3.636IleGlu: 3.636 ± 2.167
0.909IlePhe: 0.909 ± 0.542
1.818IleGly: 1.818 ± 0.775
0.0IleHis: 0.0 ± 0.0
0.909IleIle: 0.909 ± 1.165
0.0IleLys: 0.0 ± 0.0
6.364IleLeu: 6.364 ± 2.802
0.909IleMet: 0.909 ± 0.542
3.636IleAsn: 3.636 ± 0.424
3.636IlePro: 3.636 ± 2.167
2.727IleGln: 2.727 ± 1.625
1.818IleArg: 1.818 ± 1.447
1.818IleSer: 1.818 ± 2.33
1.818IleThr: 1.818 ± 2.33
0.909IleVal: 0.909 ± 0.542
0.909IleTrp: 0.909 ± 0.542
1.818IleTyr: 1.818 ± 0.775
0.0IleXaa: 0.0 ± 0.0
Lys
7.273LysAla: 7.273 ± 3.315
1.818LysCys: 1.818 ± 0.775
0.909LysAsp: 0.909 ± 1.165
0.909LysGlu: 0.909 ± 0.542
2.727LysPhe: 2.727 ± 1.084
3.636LysGly: 3.636 ± 4.66
0.909LysHis: 0.909 ± 0.542
3.636LysIle: 3.636 ± 1.401
2.727LysLys: 2.727 ± 1.084
2.727LysLeu: 2.727 ± 0.919
1.818LysMet: 1.818 ± 0.789
4.545LysAsn: 4.545 ± 2.709
3.636LysPro: 3.636 ± 1.103
1.818LysGln: 1.818 ± 1.084
1.818LysArg: 1.818 ± 0.775
4.545LysSer: 4.545 ± 1.462
2.727LysThr: 2.727 ± 1.084
0.909LysVal: 0.909 ± 1.083
0.0LysTrp: 0.0 ± 0.0
0.909LysTyr: 0.909 ± 0.542
0.0LysXaa: 0.0 ± 0.0
Leu
9.091LeuAla: 9.091 ± 1.232
1.818LeuCys: 1.818 ± 1.084
3.636LeuAsp: 3.636 ± 0.424
8.182LeuGlu: 8.182 ± 2.965
7.273LeuPhe: 7.273 ± 3.081
5.455LeuGly: 5.455 ± 2.045
0.0LeuHis: 0.0 ± 0.0
6.364LeuIle: 6.364 ± 1.308
3.636LeuLys: 3.636 ± 1.95
6.364LeuLeu: 6.364 ± 1.836
0.0LeuMet: 0.0 ± 0.0
3.636LeuAsn: 3.636 ± 2.873
4.545LeuPro: 4.545 ± 2.557
0.909LeuGln: 0.909 ± 1.083
6.364LeuArg: 6.364 ± 1.324
8.182LeuSer: 8.182 ± 2.552
6.364LeuThr: 6.364 ± 0.483
5.455LeuVal: 5.455 ± 3.608
6.364LeuTrp: 6.364 ± 2.558
2.727LeuTyr: 2.727 ± 1.804
0.0LeuXaa: 0.0 ± 0.0
Met
1.818MetAla: 1.818 ± 0.775
0.0MetCys: 0.0 ± 0.0
0.909MetAsp: 0.909 ± 0.542
1.818MetGlu: 1.818 ± 1.447
0.0MetPhe: 0.0 ± 0.0
0.909MetGly: 0.909 ± 1.083
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
4.545MetLeu: 4.545 ± 1.462
0.0MetMet: 0.0 ± 0.0
1.818MetAsn: 1.818 ± 0.986
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.909MetArg: 0.909 ± 0.542
0.909MetSer: 0.909 ± 1.083
1.818MetThr: 1.818 ± 1.084
0.909MetVal: 0.909 ± 1.165
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.636AsnAla: 3.636 ± 0.424
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.818AsnGlu: 1.818 ± 2.166
2.727AsnPhe: 2.727 ± 1.084
6.364AsnGly: 6.364 ± 2.962
0.0AsnHis: 0.0 ± 0.0
2.727AsnIle: 2.727 ± 0.784
1.818AsnLys: 1.818 ± 1.447
3.636AsnLeu: 3.636 ± 0.424
0.909AsnMet: 0.909 ± 1.165
0.909AsnAsn: 0.909 ± 1.165
2.727AsnPro: 2.727 ± 0.919
0.909AsnGln: 0.909 ± 1.083
1.818AsnArg: 1.818 ± 0.775
3.636AsnSer: 3.636 ± 2.873
4.545AsnThr: 4.545 ± 0.321
2.727AsnVal: 2.727 ± 0.784
2.727AsnTrp: 2.727 ± 0.784
2.727AsnTyr: 2.727 ± 0.784
0.0AsnXaa: 0.0 ± 0.0
Pro
2.727ProAla: 2.727 ± 1.084
0.909ProCys: 0.909 ± 0.542
0.909ProAsp: 0.909 ± 1.083
0.909ProGlu: 0.909 ± 1.083
0.0ProPhe: 0.0 ± 0.0
6.364ProGly: 6.364 ± 1.836
0.909ProHis: 0.909 ± 1.165
0.909ProIle: 0.909 ± 0.542
4.545ProLys: 4.545 ± 1.828
3.636ProLeu: 3.636 ± 1.103
0.0ProMet: 0.0 ± 0.0
2.727ProAsn: 2.727 ± 1.625
2.727ProPro: 2.727 ± 1.625
2.727ProGln: 2.727 ± 0.919
3.636ProArg: 3.636 ± 2.167
11.818ProSer: 11.818 ± 3.229
5.455ProThr: 5.455 ± 2.045
3.636ProVal: 3.636 ± 1.55
0.0ProTrp: 0.0 ± 0.0
0.909ProTyr: 0.909 ± 0.542
0.0ProXaa: 0.0 ± 0.0
Gln
1.818GlnAla: 1.818 ± 1.084
0.909GlnCys: 0.909 ± 1.083
0.909GlnAsp: 0.909 ± 1.083
0.909GlnGlu: 0.909 ± 0.542
0.909GlnPhe: 0.909 ± 1.165
2.727GlnGly: 2.727 ± 1.625
0.909GlnHis: 0.909 ± 0.542
0.909GlnIle: 0.909 ± 1.083
0.909GlnLys: 0.909 ± 1.083
4.545GlnLeu: 4.545 ± 1.462
1.818GlnMet: 1.818 ± 0.986
3.636GlnAsn: 3.636 ± 3.257
5.455GlnPro: 5.455 ± 0.783
1.818GlnGln: 1.818 ± 0.986
4.545GlnArg: 4.545 ± 3.078
1.818GlnSer: 1.818 ± 1.084
0.909GlnThr: 0.909 ± 0.542
0.909GlnVal: 0.909 ± 1.083
0.909GlnTrp: 0.909 ± 1.083
0.909GlnTyr: 0.909 ± 0.542
0.0GlnXaa: 0.0 ± 0.0
Arg
3.636ArgAla: 3.636 ± 1.55
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
1.818ArgGlu: 1.818 ± 0.775
0.0ArgPhe: 0.0 ± 0.0
6.364ArgGly: 6.364 ± 5.322
1.818ArgHis: 1.818 ± 0.775
1.818ArgIle: 1.818 ± 1.447
4.545ArgLys: 4.545 ± 2.709
6.364ArgLeu: 6.364 ± 2.576
0.0ArgMet: 0.0 ± 0.0
3.636ArgAsn: 3.636 ± 1.95
1.818ArgPro: 1.818 ± 0.775
3.636ArgGln: 3.636 ± 0.424
14.545ArgArg: 14.545 ± 12.924
1.818ArgSer: 1.818 ± 1.084
2.727ArgThr: 2.727 ± 2.09
5.455ArgVal: 5.455 ± 3.116
1.818ArgTrp: 1.818 ± 1.084
1.818ArgTyr: 1.818 ± 0.775
0.0ArgXaa: 0.0 ± 0.0
Ser
6.364SerAla: 6.364 ± 2.558
0.909SerCys: 0.909 ± 1.165
2.727SerAsp: 2.727 ± 0.919
4.545SerGlu: 4.545 ± 0.321
3.636SerPhe: 3.636 ± 1.401
10.0SerGly: 10.0 ± 2.024
2.727SerHis: 2.727 ± 0.784
3.636SerIle: 3.636 ± 1.972
5.455SerLys: 5.455 ± 1.305
10.909SerLeu: 10.909 ± 1.942
0.909SerMet: 0.909 ± 0.493
1.818SerAsn: 1.818 ± 2.166
3.636SerPro: 3.636 ± 2.167
2.727SerGln: 2.727 ± 1.625
4.545SerArg: 4.545 ± 0.321
10.0SerSer: 10.0 ± 2.481
10.0SerThr: 10.0 ± 1.502
8.182SerVal: 8.182 ± 2.353
0.0SerTrp: 0.0 ± 0.0
1.818SerTyr: 1.818 ± 0.775
0.0SerXaa: 0.0 ± 0.0
Thr
8.182ThrAla: 8.182 ± 3.251
0.909ThrCys: 0.909 ± 0.542
5.455ThrAsp: 5.455 ± 2.287
2.727ThrGlu: 2.727 ± 1.084
4.545ThrPhe: 4.545 ± 4.599
4.545ThrGly: 4.545 ± 2.709
1.818ThrHis: 1.818 ± 1.084
1.818ThrIle: 1.818 ± 0.986
0.909ThrLys: 0.909 ± 1.165
3.636ThrLeu: 3.636 ± 1.103
0.0ThrMet: 0.0 ± 0.0
3.636ThrAsn: 3.636 ± 1.55
6.364ThrPro: 6.364 ± 3.792
4.545ThrGln: 4.545 ± 4.393
1.818ThrArg: 1.818 ± 0.775
5.455ThrSer: 5.455 ± 0.783
5.455ThrThr: 5.455 ± 0.783
4.545ThrVal: 4.545 ± 1.568
0.0ThrTrp: 0.0 ± 0.0
1.818ThrTyr: 1.818 ± 1.084
0.0ThrXaa: 0.0 ± 0.0
Val
6.364ValAla: 6.364 ± 0.483
0.0ValCys: 0.0 ± 0.0
0.909ValAsp: 0.909 ± 1.083
6.364ValGlu: 6.364 ± 0.483
3.636ValPhe: 3.636 ± 1.401
1.818ValGly: 1.818 ± 0.986
1.818ValHis: 1.818 ± 0.986
1.818ValIle: 1.818 ± 1.084
2.727ValLys: 2.727 ± 1.625
8.182ValLeu: 8.182 ± 4.087
0.909ValMet: 0.909 ± 1.083
2.727ValAsn: 2.727 ± 0.919
4.545ValPro: 4.545 ± 2.557
2.727ValGln: 2.727 ± 3.249
5.455ValArg: 5.455 ± 2.287
6.364ValSer: 6.364 ± 1.836
2.727ValThr: 2.727 ± 0.919
10.0ValVal: 10.0 ± 2.834
0.0ValTrp: 0.0 ± 0.0
2.727ValTyr: 2.727 ± 1.625
0.0ValXaa: 0.0 ± 0.0
Trp
1.818TrpAla: 1.818 ± 0.775
0.0TrpCys: 0.0 ± 0.0
0.909TrpAsp: 0.909 ± 0.542
0.909TrpGlu: 0.909 ± 1.083
0.909TrpPhe: 0.909 ± 0.542
1.818TrpGly: 1.818 ± 1.084
0.909TrpHis: 0.909 ± 1.165
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.818TrpLeu: 1.818 ± 2.166
1.818TrpMet: 1.818 ± 0.775
0.0TrpAsn: 0.0 ± 0.0
0.909TrpPro: 0.909 ± 0.542
0.909TrpGln: 0.909 ± 0.542
1.818TrpArg: 1.818 ± 0.775
1.818TrpSer: 1.818 ± 0.775
0.909TrpThr: 0.909 ± 0.542
2.727TrpVal: 2.727 ± 1.625
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.818TyrAla: 1.818 ± 1.084
0.909TyrCys: 0.909 ± 0.542
3.636TyrAsp: 3.636 ± 2.167
1.818TyrGlu: 1.818 ± 1.447
0.0TyrPhe: 0.0 ± 0.0
0.909TyrGly: 0.909 ± 1.083
1.818TyrHis: 1.818 ± 1.447
0.0TyrIle: 0.0 ± 0.0
3.636TyrLys: 3.636 ± 2.894
4.545TyrLeu: 4.545 ± 1.462
0.0TyrMet: 0.0 ± 0.0
0.909TyrAsn: 0.909 ± 1.083
0.0TyrPro: 0.0 ± 0.0
0.909TyrGln: 0.909 ± 1.083
0.0TyrArg: 0.0 ± 0.0
1.818TyrSer: 1.818 ± 1.084
0.909TyrThr: 0.909 ± 0.542
4.545TyrVal: 4.545 ± 2.709
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1101 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski